FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0940, 684 aa 1>>>pF1KSDA0940 684 - 684 aa - 684 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.4478+/-0.00048; mu= -20.3285+/- 0.030 mean_var=630.8030+/-132.386, 0's: 0 Z-trim(124.5): 43 B-trim: 384 in 1/56 Lambda= 0.051065 statistics sampled from 46383 (46432) to 46383 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.801), E-opt: 0.2 (0.544), width: 16 Scan time: 14.380 The best scores are: opt bits E(85289) NP_001171608 (OMIM: 610606) cytoplasmic polyadenyl ( 684) 4791 368.1 6.4e-101 XP_005269687 (OMIM: 610606) PREDICTED: cytoplasmic ( 684) 4791 368.1 6.4e-101 XP_011537817 (OMIM: 610606) PREDICTED: cytoplasmic ( 692) 4762 365.9 2.8e-100 XP_011537825 (OMIM: 610606) PREDICTED: cytoplasmic ( 395) 2692 213.2 1.5e-54 XP_011537822 (OMIM: 610606) PREDICTED: cytoplasmic ( 598) 2693 213.4 1.9e-54 NP_001170855 (OMIM: 610605) cytoplasmic polyadenyl ( 999) 2644 210.0 3.5e-53 NP_872587 (OMIM: 610605) cytoplasmic polyadenylati ( 996) 2642 209.9 3.8e-53 XP_011537824 (OMIM: 610606) PREDICTED: cytoplasmic ( 418) 2556 203.2 1.6e-51 XP_011537821 (OMIM: 610606) PREDICTED: cytoplasmic ( 621) 2556 203.4 2.2e-51 XP_011537820 (OMIM: 610606) PREDICTED: cytoplasmic ( 640) 2556 203.4 2.2e-51 NP_055727 (OMIM: 610606) cytoplasmic polyadenylati ( 698) 2556 203.4 2.4e-51 XP_011537816 (OMIM: 610606) PREDICTED: cytoplasmic ( 707) 2556 203.4 2.4e-51 XP_011537819 (OMIM: 610606) PREDICTED: cytoplasmic ( 665) 2555 203.3 2.4e-51 XP_006717778 (OMIM: 610606) PREDICTED: cytoplasmic ( 715) 2556 203.4 2.4e-51 XP_006717777 (OMIM: 610606) PREDICTED: cytoplasmic ( 715) 2556 203.4 2.4e-51 NP_001170854 (OMIM: 610605) cytoplasmic polyadenyl (1004) 2443 195.2 1e-48 NP_872291 (OMIM: 610605) cytoplasmic polyadenylati (1026) 2357 188.9 8.2e-47 XP_005266051 (OMIM: 610607) PREDICTED: cytoplasmic ( 721) 2325 186.4 3.2e-46 XP_011512079 (OMIM: 610605) PREDICTED: cytoplasmic (1029) 2330 186.9 3.3e-46 NP_001170852 (OMIM: 610605) cytoplasmic polyadenyl (1007) 2320 186.2 5.4e-46 NP_085130 (OMIM: 610607) cytoplasmic polyadenylati ( 729) 2309 185.2 7.4e-46 NP_001170853 (OMIM: 610605) cytoplasmic polyadenyl (1034) 2180 175.9 7e-43 XP_005248192 (OMIM: 610605) PREDICTED: cytoplasmic (1037) 2141 173.0 5.1e-42 XP_016871416 (OMIM: 610606) PREDICTED: cytoplasmic ( 314) 2109 170.2 1.1e-41 NP_001295121 (OMIM: 610607) cytoplasmic polyadenyl ( 339) 2093 169.0 2.6e-41 XP_016863223 (OMIM: 610605) PREDICTED: cytoplasmic ( 463) 2066 167.2 1.3e-40 XP_016863222 (OMIM: 610605) PREDICTED: cytoplasmic ( 463) 2066 167.2 1.3e-40 NP_001295122 (OMIM: 610607) cytoplasmic polyadenyl ( 322) 1970 159.9 1.3e-38 NP_001295118 (OMIM: 610607) cytoplasmic polyadenyl ( 712) 1981 161.1 1.4e-38 NP_001295120 (OMIM: 610607) cytoplasmic polyadenyl ( 704) 1979 160.9 1.5e-38 NP_001275749 (OMIM: 607342) cytoplasmic polyadenyl ( 335) 744 69.6 2.1e-11 NP_001275748 (OMIM: 607342) cytoplasmic polyadenyl ( 486) 744 69.8 2.8e-11 NP_001073002 (OMIM: 607342) cytoplasmic polyadenyl ( 486) 744 69.8 2.8e-11 NP_001073003 (OMIM: 607342) cytoplasmic polyadenyl ( 486) 744 69.8 2.8e-11 NP_085097 (OMIM: 607342) cytoplasmic polyadenylati ( 561) 744 69.8 3.1e-11 NP_001073001 (OMIM: 607342) cytoplasmic polyadenyl ( 491) 609 59.8 2.8e-08 XP_011512081 (OMIM: 610605) PREDICTED: cytoplasmic ( 666) 472 49.9 3.8e-05 >>NP_001171608 (OMIM: 610606) cytoplasmic polyadenylatio (684 aa) initn: 4791 init1: 4791 opt: 4791 Z-score: 1932.8 bits: 368.1 E(85289): 6.4e-101 Smith-Waterman score: 4791; 100.0% identity (100.0% similar) in 684 aa overlap (1-684:1-684) 10 20 30 40 50 60 pF1KSD MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD HEPLKGRMGINFHHPGTDNIMALNSRSSLFPFEDAFLDDSHGDQALSSGLSSPTRCQNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HEPLKGRMGINFHHPGTDNIMALNSRSSLFPFEDAFLDDSHGDQALSSGLSSPTRCQNGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRA 610 620 630 640 650 660 670 680 pF1KSD GREFHKPLVKEGGDRPRHVPFRWS :::::::::::::::::::::::: NP_001 GREFHKPLVKEGGDRPRHVPFRWS 670 680 >>XP_005269687 (OMIM: 610606) PREDICTED: cytoplasmic pol (684 aa) initn: 4791 init1: 4791 opt: 4791 Z-score: 1932.8 bits: 368.1 E(85289): 6.4e-101 Smith-Waterman score: 4791; 100.0% identity (100.0% similar) in 684 aa overlap (1-684:1-684) 10 20 30 40 50 60 pF1KSD MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD HEPLKGRMGINFHHPGTDNIMALNSRSSLFPFEDAFLDDSHGDQALSSGLSSPTRCQNGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HEPLKGRMGINFHHPGTDNIMALNSRSSLFPFEDAFLDDSHGDQALSSGLSSPTRCQNGE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD LQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRA 610 620 630 640 650 660 670 680 pF1KSD GREFHKPLVKEGGDRPRHVPFRWS :::::::::::::::::::::::: XP_005 GREFHKPLVKEGGDRPRHVPFRWS 670 680 >>XP_011537817 (OMIM: 610606) PREDICTED: cytoplasmic pol (692 aa) initn: 2691 init1: 2691 opt: 4762 Z-score: 1921.2 bits: 365.9 E(85289): 2.8e-100 Smith-Waterman score: 4762; 98.7% identity (98.8% similar) in 692 aa overlap (1-684:1-692) 10 20 30 40 50 60 pF1KSD MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 310 320 330 340 350 360 370 380 390 400 410 pF1KSD HEPLKGRMGINFHHPGTDNIMALNSRS--------SLFPFEDAFLDDSHGDQALSSGLSS ::::::::::::::::::::::::.:: ::::::::::::::::::::::::: XP_011 HEPLKGRMGINFHHPGTDNIMALNTRSYGRRRGRSSLFPFEDAFLDDSHGDQALSSGLSS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD PTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGY 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD AFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLD 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD PRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIA 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD AISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYC 610 620 630 640 650 660 660 670 680 pF1KSD WASIHSRAGREFHKPLVKEGGDRPRHVPFRWS :::::::::::::::::::::::::::::::: XP_011 WASIHSRAGREFHKPLVKEGGDRPRHVPFRWS 670 680 690 >>XP_011537825 (OMIM: 610606) PREDICTED: cytoplasmic pol (395 aa) initn: 3033 init1: 2692 opt: 2692 Z-score: 1100.3 bits: 213.2 E(85289): 1.5e-54 Smith-Waterman score: 2692; 99.0% identity (100.0% similar) in 390 aa overlap (1-390:1-390) 10 20 30 40 50 60 pF1KSD MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD HEPLKGRMGINFHHPGTDNIMALNSRSSLFPFEDAFLDDSHGDQALSSGLSSPTRCQNGE ::::::::::::::::::::::::...::. XP_011 HEPLKGRMGINFHHPGTDNIMALNKQQSLYDSTSV 370 380 390 >>XP_011537822 (OMIM: 610606) PREDICTED: cytoplasmic pol (598 aa) initn: 2686 init1: 2686 opt: 2693 Z-score: 1098.3 bits: 213.4 E(85289): 1.9e-54 Smith-Waterman score: 4009; 87.4% identity (87.4% similar) in 684 aa overlap (1-684:1-598) 10 20 30 40 50 60 pF1KSD MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD HEPLKGRMGINFHHPGTDNIMALNSRSSLFPFEDAFLDDSHGDQALSSGLSSPTRCQNGE ::::::::::::::::::::::::: XP_011 HEPLKGRMGINFHHPGTDNIMALNS----------------------------------- 370 380 430 440 450 460 470 480 pF1KSD RVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEE ::::::::: XP_011 ---------------------------------------------------YAFLLFQEE 390 490 500 510 520 530 540 pF1KSD SSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVG 400 410 420 430 440 450 550 560 570 580 590 600 pF1KSD GVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQ 460 470 480 490 500 510 610 620 630 640 650 660 pF1KSD LQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRA 520 530 540 550 560 570 670 680 pF1KSD GREFHKPLVKEGGDRPRHVPFRWS :::::::::::::::::::::::: XP_011 GREFHKPLVKEGGDRPRHVPFRWS 580 590 >>NP_001170855 (OMIM: 610605) cytoplasmic polyadenylatio (999 aa) initn: 2508 init1: 1835 opt: 2644 Z-score: 1075.8 bits: 210.0 E(85289): 3.5e-53 Smith-Waterman score: 2700; 62.8% identity (77.3% similar) in 678 aa overlap (42-684:370-999) 20 30 40 50 60 70 pF1KSD TQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVP-ALSPAAAPPAPNGPDK : .: : . ..: ... :. :: :. : NP_001 SSLQSPDLPHPGGGGGGGGGGPPGGGGGGGSASPPPLPGFGTPWSVQTASPPPQPQQPPP 340 350 360 370 380 390 80 90 100 110 120 pF1KSD MQ-MESPLLPGLSFHQPPQQPPPPQEPAAPGAS-LSPSFGSTWSTGT----TNAVEDSFF : ...: : :::::: :: : ::.: .:. :: : .. . :..:. NP_001 TQPQQQP--P------PPQQPPQPQ-PQPPGSSATTPGGGSGGSLSAMPPPSPDSENGFY 400 410 420 430 440 450 130 140 150 160 170 pF1KSD QGITPVNGTMLFQNF----PHHVN----PVFGGTFSPQIGLAQTQHHQQPPPPA---PAP :. . .: .: :: . :. :: . : .. ::::: : NP_001 PGLPSSMNPAFFPSFSPVSPHGCTGLSVPTSGGGGGGFGGPFSATAVPPPPPPAMNIPQQ 460 470 480 490 500 510 180 190 200 210 220 pF1KSD QPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAY--------GHQPIMTSKPSSSSA :: :: : : ::.::::.:: : ...::::. :::.. ..: NP_001 QPPPPAAPQQ---PQSRRSPVSP-QLQQQHQAAAAAFLQQRNSYNHHQPLLKQSP----- 520 530 540 550 560 230 240 250 260 270 280 pF1KSD VAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSP :..::: ..:.. : ::... ::: ::. : ..:.:. NP_001 ----------------WSNHQS--SGWGTGSMSWGAMH-GRDHRRT-----G-NMGIPGT 570 580 590 290 300 310 320 330 340 pF1KSD LNPISPLKKPFSSNVIAPPKFPRAAP-LTSKSWMEDNAFRTDNGNN-LLPFQ---DRSRP .: :::::::::.:::::::: :..: :: :::.:::.:::::..: :::.: :::: NP_001 MNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQVRMDRSRM 600 610 620 630 640 650 350 360 370 380 390 400 pF1KSD YDTFNLHSLENSLMDMIRTDHEPLKGRMGINFHHPGTDNIMALNSRSSLFPFEDAFLDDS ::..:.:::::::.:..:..:.:::::. .. ::::::.. ::.::::::..:..:::. NP_001 YDSLNMHSLENSLIDIMRAEHDPLKGRL--SYPHPGTDNLLMLNGRSSLFPIDDGLLDDG 660 670 680 690 700 710 410 420 430 440 450 pF1KSD HGDQALSSGLSSPTRC----QNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVD :.::. . :.::: : :::::.::.::::::::::::::::::::::::::::::: NP_001 HSDQV--GVLNSPT-CYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVD 720 730 740 750 760 770 460 470 480 490 500 510 pF1KSD WPHKAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPW ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_001 WPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPW 780 790 800 810 820 830 520 530 540 550 560 570 pF1KSD NLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYP 840 850 860 870 880 890 580 590 600 610 620 630 pF1KSD KGAGRVAFSNQQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAP :::::::::::::::::::::::::::.:::::::::::::::::::::::.:::::::: NP_001 KGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAP 900 910 920 930 940 950 640 650 660 670 680 pF1KSD FFCANVTCLQYYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS ::::::::::::::.:::.:::::::::::::::::.::::.. :::. NP_001 FFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN 960 970 980 990 >>NP_872587 (OMIM: 610605) cytoplasmic polyadenylation e (996 aa) initn: 2383 init1: 1845 opt: 2642 Z-score: 1075.0 bits: 209.9 E(85289): 3.8e-53 Smith-Waterman score: 2716; 63.1% identity (77.6% similar) in 675 aa overlap (42-684:370-996) 20 30 40 50 60 70 pF1KSD TQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVP-ALSPAAAPPAPNGPDK : .: : . ..: ... :. :: :. : NP_872 SSLQSPDLPHPGGGGGGGGGGPPGGGGGGGSASPPPLPGFGTPWSVQTASPPPQPQQPPP 340 350 360 370 380 390 80 90 100 110 120 pF1KSD MQ-MESPLLPGLSFHQPPQQPPPPQEPAAPGAS-LSPSFGSTWSTGT----TNAVEDSFF : ...: : :::::: :: : ::.: .:. :: : .. . :..:. NP_872 TQPQQQP--P------PPQQPPQPQ-PQPPGSSATTPGGGSGGSLSAMPPPSPDSENGFY 400 410 420 430 440 450 130 140 150 160 170 pF1KSD QGITPVNGTMLFQNF----PHHVN----PVFGGTFSPQIGLAQTQHHQQPPPPA---PAP :. . .: .: :: . :. :: . : .. ::::: : NP_872 PGLPSSMNPAFFPSFSPVSPHGCTGLSVPTSGGGGGGFGGPFSATAVPPPPPPAMNIPQQ 460 470 480 490 500 510 180 190 200 210 220 pF1KSD QPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAY--------GHQPIMTSKPSSSSA :: :: : : ::.::::.:: : ...::::. :::.. ..: NP_872 QPPPPAAPQQ---PQSRRSPVSP-QLQQQHQAAAAAFLQQRNSYNHHQPLLKQSP----- 520 530 540 550 560 230 240 250 260 270 280 pF1KSD VAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSP :..::: ..:.. : ::... ::: ::. : ..:.:. NP_872 ----------------WSNHQS--SGWGTGSMSWGAMH-GRDHRRT-----G-NMGIPGT 570 580 590 290 300 310 320 330 340 pF1KSD LNPISPLKKPFSSNVIAPPKFPRAAP-LTSKSWMEDNAFRTDNGNN-LLPFQDRSRPYDT .: :::::::::.:::::::: :..: :: :::.:::.:::::..: :::.::::: ::. NP_872 MNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQDRSRMYDS 600 610 620 630 640 650 350 360 370 380 390 400 pF1KSD FNLHSLENSLMDMIRTDHEPLKGRMGINFHHPGTDNIMALNSRSSLFPFEDAFLDDSHGD .:.:::::::.:..:..:.:::::. .. ::::::.. ::.::::::..:..:::.:.: NP_872 LNMHSLENSLIDIMRAEHDPLKGRL--SYPHPGTDNLLMLNGRSSLFPIDDGLLDDGHSD 660 670 680 690 700 710 410 420 430 440 450 pF1KSD QALSSGLSSPTRC----QNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPH :. . :.::: : :::::.::.:::::::::::::::::::::::::::::::::: NP_872 QV--GVLNSPT-CYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPH 720 730 740 750 760 770 460 470 480 490 500 510 pF1KSD KAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLS :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: NP_872 KAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLS 780 790 800 810 820 830 520 530 540 550 560 570 pF1KSD DSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_872 DSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGA 840 850 860 870 880 890 580 590 600 610 620 630 pF1KSD GRVAFSNQQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFC ::::::::::::::::::::::::.:::::::::::::::::::::::.::::::::::: NP_872 GRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFC 900 910 920 930 940 950 640 650 660 670 680 pF1KSD ANVTCLQYYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS :::::::::::.:::.:::::::::::::::::.::::.. :::. NP_872 ANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN 960 970 980 990 >>XP_011537824 (OMIM: 610606) PREDICTED: cytoplasmic pol (418 aa) initn: 2689 init1: 2551 opt: 2556 Z-score: 1045.8 bits: 203.2 E(85289): 1.6e-51 Smith-Waterman score: 2636; 93.5% identity (94.4% similar) in 413 aa overlap (1-390:1-413) 10 20 30 40 50 60 pF1KSD MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 310 320 330 340 350 360 370 380 390 pF1KSD HEPLKG-----------------------RMGINFHHPGTDNIMALNSRSSLFPFEDAFL :::::: ::::::::::::::::::...::. XP_011 HEPLKGKHYPPSGPPMSFADIMWRNHFAGRMGINFHHPGTDNIMALNKQQSLYDSTSV 370 380 390 400 410 400 410 420 430 440 450 pF1KSD DDSHGDQALSSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDW >>XP_011537821 (OMIM: 610606) PREDICTED: cytoplasmic pol (621 aa) initn: 4046 init1: 2551 opt: 2556 Z-score: 1043.5 bits: 203.4 E(85289): 2.2e-51 Smith-Waterman score: 3954; 86.3% identity (88.7% similar) in 684 aa overlap (1-684:1-621) 10 20 30 40 50 60 pF1KSD MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD HEPLKGRMGINFHHPGTDNIMALNSRSSLFPFEDAFLDDSHGDQALSSGLSSPTRCQNGE ::::::. :.: . :. : : . XP_011 HEPLKGK-----HYPPSGPPMS---------FADIMW----------------------- 370 380 430 440 450 460 470 480 pF1KSD RVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEE :. :.: :.: ... : . . . . ..::::::::: XP_011 ------RNHFAG----------------RMG---INFHHPG-TDNIMALNSYAFLLFQEE 390 400 410 490 500 510 520 530 540 pF1KSD SSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVG 420 430 440 450 460 470 550 560 570 580 590 600 pF1KSD GVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQ 480 490 500 510 520 530 610 620 630 640 650 660 pF1KSD LQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRA 540 550 560 570 580 590 670 680 pF1KSD GREFHKPLVKEGGDRPRHVPFRWS :::::::::::::::::::::::: XP_011 GREFHKPLVKEGGDRPRHVPFRWS 600 610 620 >>XP_011537820 (OMIM: 610606) PREDICTED: cytoplasmic pol (640 aa) initn: 4067 init1: 2551 opt: 2556 Z-score: 1043.4 bits: 203.4 E(85289): 2.2e-51 Smith-Waterman score: 4127; 95.0% identity (95.2% similar) in 640 aa overlap (1-609:1-640) 10 20 30 40 50 60 pF1KSD MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MQDDLLMDKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPAPQPAQPAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTD 310 320 330 340 350 360 370 380 pF1KSD HEPLKG-----------------------RMGINFHHPGTDNIMALNSRS--------SL :::::: ::::::::::::::::::.:: :: XP_011 HEPLKGKHYPPSGPPMSFADIMWRNHFAGRMGINFHHPGTDNIMALNTRSYGRRRGRSSL 370 380 390 400 410 420 390 400 410 420 430 440 pF1KSD FPFEDAFLDDSHGDQALSSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FPFEDAFLDDSHGDQALSSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRR 430 440 450 460 470 480 450 460 470 480 490 500 pF1KSD FGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDK 490 500 510 520 530 540 510 520 530 540 550 560 pF1KSD PVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDT 550 560 570 580 590 600 570 580 590 600 610 620 pF1KSD DPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTR :::::::::::::::::::::::::::::::::::::::: XP_011 DPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHNDIDKR 610 620 630 640 630 640 650 660 670 680 pF1KSD CGGKFAPFFCANVTCLQYYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS 684 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:19:47 2016 done: Thu Nov 3 04:19:49 2016 Total Scan time: 14.380 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]