FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0948, 521 aa 1>>>pF1KSDA0948 521 - 521 aa - 521 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4856+/-0.000327; mu= 18.4745+/- 0.021 mean_var=82.1642+/-15.870, 0's: 0 Z-trim(116.6): 17 B-trim: 47 in 2/54 Lambda= 0.141492 statistics sampled from 27801 (27817) to 27801 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.326), width: 16 Scan time: 9.830 The best scores are: opt bits E(85289) NP_112162 (OMIM: 611325) protein TBRG4 isoform 2 [ ( 521) 3434 710.7 2.6e-204 NP_954573 (OMIM: 611325) protein TBRG4 isoform 2 [ ( 521) 3434 710.7 2.6e-204 NP_004740 (OMIM: 611325) protein TBRG4 isoform 1 [ ( 631) 1873 392.1 2.6e-108 NP_001248763 (OMIM: 611325) protein TBRG4 isoform ( 642) 1873 392.1 2.6e-108 XP_011514063 (OMIM: 606965) PREDICTED: fas-activat ( 494) 267 64.2 1e-09 XP_011514064 (OMIM: 606965) PREDICTED: fas-activat ( 462) 236 57.9 7.9e-08 XP_016867194 (OMIM: 606965) PREDICTED: fas-activat ( 353) 207 51.9 3.9e-06 >>NP_112162 (OMIM: 611325) protein TBRG4 isoform 2 [Homo (521 aa) initn: 3434 init1: 3434 opt: 3434 Z-score: 3788.9 bits: 710.7 E(85289): 2.6e-204 Smith-Waterman score: 3434; 100.0% identity (100.0% similar) in 521 aa overlap (1-521:1-521) 10 20 30 40 50 60 pF1KSD MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RLEDKHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 RLEDKHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 DLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 PLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 DGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIV 430 440 450 460 470 480 490 500 510 520 pF1KSD AAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK ::::::::::::::::::::::::::::::::::::::::: NP_112 AAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 490 500 510 520 >>NP_954573 (OMIM: 611325) protein TBRG4 isoform 2 [Homo (521 aa) initn: 3434 init1: 3434 opt: 3434 Z-score: 3788.9 bits: 710.7 E(85289): 2.6e-204 Smith-Waterman score: 3434; 100.0% identity (100.0% similar) in 521 aa overlap (1-521:1-521) 10 20 30 40 50 60 pF1KSD MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 LIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 YKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVGHLSEPLMN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RLEDKHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 RLEDKHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD DLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 DLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEYSG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 PLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_954 DGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIV 430 440 450 460 470 480 490 500 510 520 pF1KSD AAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK ::::::::::::::::::::::::::::::::::::::::: NP_954 AAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 490 500 510 520 >>NP_004740 (OMIM: 611325) protein TBRG4 isoform 1 [Homo (631 aa) initn: 1846 init1: 1846 opt: 1873 Z-score: 2065.7 bits: 392.1 E(85289): 2.6e-108 Smith-Waterman score: 2693; 80.1% identity (80.1% similar) in 553 aa overlap (79-521:79-631) 50 60 70 80 90 100 pF1KSD HLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLS :::::::::::::::::::::::::::::: NP_004 HLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLS 50 60 70 80 90 100 110 120 130 140 150 160 pF1KSD HLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 HLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSV 110 120 130 140 150 160 170 180 190 200 210 220 pF1KSD EQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVM 170 180 190 200 210 220 230 240 pF1KSD MKVGHLSEPLMNRLEDK------------------------------------------- ::::::::::::::::: NP_004 MKVGHLSEPLMNRLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPF 230 240 250 260 270 280 pF1KSD ------------------------------------------------------------ NP_004 SLTKDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLP 290 300 310 320 330 340 250 260 270 280 290 pF1KSD -------HVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPAL ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LFEAFAQHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPAL 350 360 370 380 390 400 300 310 320 330 340 350 pF1KSD QVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEY 410 420 430 440 450 460 360 370 380 390 400 410 pF1KSD SGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLL 470 480 490 500 510 520 420 430 440 450 460 470 pF1KSD DSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRH 530 540 550 560 570 580 480 490 500 510 520 pF1KSD IVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK ::::::::::::::::::::::::::::::::::::::::::: NP_004 IVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 590 600 610 620 630 >-- initn: 511 init1: 511 opt: 511 Z-score: 563.1 bits: 114.1 E(85289): 1.3e-24 Smith-Waterman score: 511; 100.0% identity (100.0% similar) in 78 aa overlap (1-78:1-78) 10 20 30 40 50 60 pF1KSD MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISHLPGSLMEPVEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL :::::::::::::::::: NP_004 ERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSHLLSEKPEDKGL 70 80 90 100 110 120 >>NP_001248763 (OMIM: 611325) protein TBRG4 isoform 3 [H (642 aa) initn: 1846 init1: 1846 opt: 1873 Z-score: 2065.5 bits: 392.1 E(85289): 2.6e-108 Smith-Waterman score: 2693; 80.1% identity (80.1% similar) in 553 aa overlap (79-521:90-642) 50 60 70 80 90 100 pF1KSD HLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLS :::::::::::::::::::::::::::::: NP_001 HLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD HLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KSD EQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVM 180 190 200 210 220 230 230 240 pF1KSD MKVGHLSEPLMNRLEDK------------------------------------------- ::::::::::::::::: NP_001 MKVGHLSEPLMNRLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPF 240 250 260 270 280 290 pF1KSD ------------------------------------------------------------ NP_001 SLTKDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLP 300 310 320 330 340 350 250 260 270 280 290 pF1KSD -------HVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPAL ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFEAFAQHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPAL 360 370 380 390 400 410 300 310 320 330 340 350 pF1KSD QVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATALLEYPEY 420 430 440 450 460 470 360 370 380 390 400 410 pF1KSD SGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLL 480 490 500 510 520 530 420 430 440 450 460 470 pF1KSD DSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRH 540 550 560 570 580 590 480 490 500 510 520 pF1KSD IVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK ::::::::::::::::::::::::::::::::::::::::::: NP_001 IVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK 600 610 620 630 640 >-- initn: 511 init1: 511 opt: 511 Z-score: 563.0 bits: 114.1 E(85289): 1.3e-24 Smith-Waterman score: 511; 100.0% identity (100.0% similar) in 78 aa overlap (1-78:12-89) 10 20 30 40 pF1KSD MAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISH ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEVSGGARCDIMAAHLVKRCTCLLREAARQAPAMAPVGRLRLAWVAHKTLTSSATSPISH 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD LPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSH ::::::::::::::::::::::::::::: NP_001 LPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHDLDSNQAAMVLIRLSH 70 80 90 100 110 120 >>XP_011514063 (OMIM: 606965) PREDICTED: fas-activated s (494 aa) initn: 55 init1: 55 opt: 267 Z-score: 295.4 bits: 64.2 E(85289): 1e-09 Smith-Waterman score: 267; 25.9% identity (53.6% similar) in 390 aa overlap (72-447:85-462) 50 60 70 80 90 100 pF1KSD SATSPISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHD-LDSNQA ...:...: : :::. :: . . . ... XP_011 IPPVQPCCLGPSKWGDRPVGGGPSAGPVQGLQRLLEQAKSPGELLRWLGQNPSKVRAHHY 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD AMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPK ...: ::..::. .:. .... ...: :. . : :. : ::.:. XP_011 SVALRRLGQLLGSRPRPPP--VEQVTLQDLSQLIIRNCPSFDIHTIHVCLHLAVLLGFPS 120 130 140 150 160 170 170 180 190 200 210 pF1KSD ASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELL----AELLTHLERRWT . . ..::: : :. : : .. : ..: .:.. : . XP_011 DGPLVCALEQERRLRLPPKPPPPLQPLLRGGQGLEAALSCPRFLRYPRQHLISSLAEARP 180 190 200 210 220 230 220 230 240 250 260 270 pF1KSD EIEDSHTLVTVMMKVGH--LSEP-LMNRLEDKHVLNRAQDITLPHLCSVLLAFARLNFHP : :..: . ..... : :: :.. . :....: .. . ...: :.:::. : XP_011 EELTPHVMVLLAQHLARHRLREPQLLEAIAHFLVVQETQ-LSSKVVQKLVLPFGRLNYLP 240 250 260 270 280 290 280 290 300 310 320 330 pF1KSD DQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGK :.::. ... :. : :. : :... .:: :. :. :. : : :....: XP_011 -LEQQFMPCLERILARE-AGVAPLATVNILMSLCQLRCLPFRALHFVFSPGF-INYISGT 300 310 320 330 340 340 350 360 370 380 pF1KSD SQKDQNTFQKLLHINATAL-LEYPEYSGPLLPASA---VAPGPSALDR-KVTPLQKEL-Q . .. : . ::. :: : : :: :: . : : :: . .:.. XP_011 PHA--LIVRRYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVA 350 360 370 380 390 400 390 400 410 420 430 440 pF1KSD ETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPG : :. ::: .: .... :. : . .:.: :::: : : : .: : : XP_011 EGLRQLLGE-EKYRQDLTVPPGYCTDFLLCASSSGAVLPVRT-QDPFLPYPP--RSCPQG 410 420 430 440 450 460 450 460 470 480 490 500 pF1KSD SKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYL XP_011 QAASSATTRDPAQSYPSRNWSPREACPSSRAT 470 480 490 >>XP_011514064 (OMIM: 606965) PREDICTED: fas-activated s (462 aa) initn: 55 init1: 55 opt: 236 Z-score: 261.6 bits: 57.9 E(85289): 7.9e-08 Smith-Waterman score: 236; 25.1% identity (53.3% similar) in 390 aa overlap (72-447:85-457) 50 60 70 80 90 100 pF1KSD SATSPISHLPGSLMEPVEKERASTPYIEKQVDHLIKKATRPEELLELLGGSHD-LDSNQA ...:...: : :::. :: . . . ... XP_011 IPPVQPCCLGPSKWGDRPVGGGPSAGPVQGLQRLLEQAKSPGELLRWLGQNPSKVRAHHY 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD AMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPK ...: ::..::. .:. .... ...: :. . : :. : ::.:. XP_011 SVALRRLGQLLGSRPRPPP--VEQVTLQDLSQLIIRNCPSFDIHTIHVCLHLAVLLGFPS 120 130 140 150 160 170 170 180 190 200 210 pF1KSD ASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELL----AELLTHLERRWT . . ..::: : :. : : .. : ..: .:.. : . XP_011 DGPLVCALEQERRLRLPPKPPPPLQPLLRGGQGLEAALSCPRFLRYPRQHLISSLAEARP 180 190 200 210 220 230 220 230 240 250 260 270 pF1KSD EIEDSHTLVTVMMKVGH--LSEP-LMNRLEDKHVLNRAQDITLPHLCSVLLAFARLNFHP : :..: . ..... : :: :.. . :....: .. . ...: :.:::. : XP_011 EELTPHVMVLLAQHLARHRLREPQLLEAIAHFLVVQETQ-LSSKVVQKLVLPFGRLNYLP 240 250 260 270 280 290 280 290 300 310 320 330 pF1KSD DQEDQFFSLVHEKLGSELPGLEPALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGK :.::. ... :. : :. : :... .:: :. :. :. : : :....: XP_011 -LEQQFMPCLERILARE-AGVAPLATVNILMSLCQLRCLPFRALHFVFSPGF-INYISGT 300 310 320 330 340 340 350 360 370 380 pF1KSD SQKDQNTFQKLLHINATAL-LEYPEYSGPLLPASA---VAPGPSALDR-KVTPLQKEL-Q . .. : . ::. :: : : :: :: . : : :: . .:.. XP_011 PHA--LIVRRYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVA 350 360 370 380 390 400 390 400 410 420 430 440 pF1KSD ETLKGLLGSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPG : :. ::: .: .... :. . : . : .: : :: : ...: :: XP_011 EGLRQLLGE-EKYRQDLTVPPGYCT---ATLRGTG--VPERP--APAQELPE-AEAPGPG 410 420 430 440 450 450 460 470 480 490 500 pF1KSD SKRLAFLRWEFPNFNSRSKDLLGRFVLARRHIVAAGFLIVDVPFYEWLELKSEWQKGAYL XP_011 PALGA 460 >>XP_016867194 (OMIM: 606965) PREDICTED: fas-activated s (353 aa) initn: 55 init1: 55 opt: 207 Z-score: 231.2 bits: 51.9 E(85289): 3.9e-06 Smith-Waterman score: 207; 26.5% identity (51.7% similar) in 302 aa overlap (159-447:30-321) 130 140 150 160 170 180 pF1KSD QLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEVRWRMRKLKYKHLAFLA :. . . ..::: : :. : : XP_016 MRRPRGEPGPRAPRPTEGATCAGPGESCFPSDGPLVCALEQERRLRLPPKPPPPLQPLL 10 20 30 40 50 190 200 210 220 230 240 pF1KSD ESCATLSQEQHSQELL----AELLTHLERRWTEIEDSHTLVTVMMKVGH--LSEP-LMNR .. : ..: .:.. : . : :..: . ..... : :: :.. XP_016 RGGQGLEAALSCPRFLRYPRQHLISSLAEARPEELTPHVMVLLAQHLARHRLREPQLLEA 60 70 80 90 100 110 250 260 270 280 290 300 pF1KSD LEDKHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSLVHEKLGSELPGLEPALQVD . :....: .. . ...: :.:::. : :.::. ... :. : :. : :. XP_016 IAHFLVVQETQ-LSSKVVQKLVLPFGRLNYLP-LEQQFMPCLERILARE-AGVAPLATVN 120 130 140 150 160 170 310 320 330 340 350 360 pF1KSD LVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNTFQKLLHINATAL-LEYPEYSG .. .:: :. :. :. : : :....: . .. : . ::. :: : : : XP_016 ILMSLCQLRCLPFRALHFVFSPGF-INYISGTPHA--LIVRRYLSLLDTAVELELPGYRG 180 190 200 210 220 230 370 380 390 400 410 pF1KSD PLLPASA---VAPGPSALDR-KVTPLQKEL-QETLKGLLGSADKGSLEVATQYGWVLDAE : :: . : : :: . .:.. : :. ::: .: .... :. : XP_016 PRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGE-EKYRQDLTVPPGYCTDFL 240 250 260 270 280 290 420 430 440 450 460 470 pF1KSD VLLDSDGEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLA . .:.: :::: : : : .: : : XP_016 LCASSSGAVLPVRT-QDPFLPYPP--RSCPQGQAASSATTRDPAQSYPSRNWSPREACPS 300 310 320 330 340 480 490 500 510 520 pF1KSD RRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELAK XP_016 SRAT 350 521 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:21:05 2016 done: Thu Nov 3 04:21:07 2016 Total Scan time: 9.830 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]