FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0955, 431 aa 1>>>pF1KSDA0955 431 - 431 aa - 431 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9467+/-0.000393; mu= 13.8669+/- 0.024 mean_var=77.1778+/-15.374, 0's: 0 Z-trim(113.2): 69 B-trim: 199 in 2/53 Lambda= 0.145992 statistics sampled from 22343 (22412) to 22343 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.263), width: 16 Scan time: 8.930 The best scores are: opt bits E(85289) XP_006723167 (OMIM: 609051) PREDICTED: caspase rec ( 431) 2872 614.7 1.5e-175 XP_016881975 (OMIM: 609051) PREDICTED: caspase rec ( 455) 2872 614.7 1.6e-175 XP_011524950 (OMIM: 609051) PREDICTED: caspase rec ( 463) 2872 614.7 1.6e-175 XP_006723164 (OMIM: 609051) PREDICTED: caspase rec ( 432) 2860 612.1 8.6e-175 XP_006723165 (OMIM: 609051) PREDICTED: caspase rec ( 432) 2860 612.1 8.6e-175 XP_006723161 (OMIM: 609051) PREDICTED: caspase rec ( 456) 2860 612.1 9e-175 XP_006723162 (OMIM: 609051) PREDICTED: caspase rec ( 456) 2860 612.1 9e-175 XP_011524949 (OMIM: 609051) PREDICTED: caspase rec ( 464) 2860 612.1 9.1e-175 XP_011524948 (OMIM: 609051) PREDICTED: caspase rec ( 464) 2860 612.1 9.1e-175 XP_016881973 (OMIM: 609051) PREDICTED: caspase rec ( 486) 2698 578.0 1.8e-164 XP_016881971 (OMIM: 609051) PREDICTED: caspase rec ( 536) 2698 578.0 1.9e-164 XP_006723157 (OMIM: 609051) PREDICTED: caspase rec ( 536) 2698 578.0 1.9e-164 XP_016881977 (OMIM: 609051) PREDICTED: caspase rec ( 425) 2686 575.5 9.1e-164 XP_016881976 (OMIM: 609051) PREDICTED: caspase rec ( 425) 2686 575.5 9.1e-164 XP_016881978 (OMIM: 609051) PREDICTED: caspase rec ( 425) 2686 575.5 9.1e-164 NP_055774 (OMIM: 609051) caspase recruitment domai ( 487) 2686 575.5 1e-163 XP_006723159 (OMIM: 609051) PREDICTED: caspase rec ( 487) 2686 575.5 1e-163 XP_006723158 (OMIM: 609051) PREDICTED: caspase rec ( 487) 2686 575.5 1e-163 NP_001171830 (OMIM: 609051) caspase recruitment do ( 487) 2686 575.5 1e-163 XP_016881972 (OMIM: 609051) PREDICTED: caspase rec ( 487) 2686 575.5 1e-163 XP_006723160 (OMIM: 609051) PREDICTED: caspase rec ( 487) 2686 575.5 1e-163 XP_006723155 (OMIM: 609051) PREDICTED: caspase rec ( 537) 2686 575.5 1.1e-163 XP_011524943 (OMIM: 609051) PREDICTED: caspase rec ( 537) 2686 575.5 1.1e-163 NP_001171829 (OMIM: 609051) caspase recruitment do ( 537) 2686 575.5 1.1e-163 XP_011524946 (OMIM: 609051) PREDICTED: caspase rec ( 537) 2686 575.5 1.1e-163 XP_011524944 (OMIM: 609051) PREDICTED: caspase rec ( 537) 2686 575.5 1.1e-163 XP_006723154 (OMIM: 609051) PREDICTED: caspase rec ( 537) 2686 575.5 1.1e-163 XP_011524945 (OMIM: 609051) PREDICTED: caspase rec ( 537) 2686 575.5 1.1e-163 XP_006723156 (OMIM: 609051) PREDICTED: caspase rec ( 537) 2686 575.5 1.1e-163 XP_016881974 (OMIM: 609051) PREDICTED: caspase rec ( 464) 2142 460.9 3e-129 XP_006723172 (OMIM: 609051) PREDICTED: caspase rec ( 286) 1905 410.9 2.1e-114 XP_016881987 (OMIM: 609051) PREDICTED: caspase rec ( 286) 1905 410.9 2.1e-114 XP_011524955 (OMIM: 609051) PREDICTED: caspase rec ( 318) 1905 410.9 2.3e-114 XP_016881986 (OMIM: 609051) PREDICTED: caspase rec ( 287) 1893 408.4 1.2e-113 XP_016881985 (OMIM: 609051) PREDICTED: caspase rec ( 287) 1893 408.4 1.2e-113 XP_016881984 (OMIM: 609051) PREDICTED: caspase rec ( 311) 1893 408.4 1.3e-113 XP_016881988 (OMIM: 609051) PREDICTED: caspase rec ( 281) 1731 374.2 2.3e-103 XP_016881982 (OMIM: 609051) PREDICTED: caspase rec ( 342) 1719 371.8 1.5e-102 XP_016881981 (OMIM: 609051) PREDICTED: caspase rec ( 342) 1719 371.8 1.5e-102 XP_016881983 (OMIM: 609051) PREDICTED: caspase rec ( 342) 1719 371.8 1.5e-102 XP_016881980 (OMIM: 609051) PREDICTED: caspase rec ( 388) 1719 371.8 1.7e-102 XP_016881979 (OMIM: 609051) PREDICTED: caspase rec ( 392) 1719 371.8 1.7e-102 XP_006723169 (OMIM: 609051) PREDICTED: caspase rec ( 392) 1719 371.8 1.7e-102 NP_001171831 (OMIM: 609051) caspase recruitment do ( 392) 1719 371.8 1.7e-102 NP_001171832 (OMIM: 609051) caspase recruitment do ( 392) 1719 371.8 1.7e-102 XP_011524952 (OMIM: 609051) PREDICTED: caspase rec ( 392) 1719 371.8 1.7e-102 XP_006723170 (OMIM: 609051) PREDICTED: caspase rec ( 350) 1441 313.2 6.7e-85 NP_127499 (OMIM: 606579,606636,615225) NACHT, LRR (1443) 945 209.0 6.4e-53 NP_127497 (OMIM: 606579,606636,615225) NACHT, LRR (1473) 945 209.0 6.5e-53 NP_001028225 (OMIM: 606579,606636,615225) NACHT, L (1375) 924 204.6 1.3e-51 >>XP_006723167 (OMIM: 609051) PREDICTED: caspase recruit (431 aa) initn: 2872 init1: 2872 opt: 2872 Z-score: 3272.7 bits: 614.7 E(85289): 1.5e-175 Smith-Waterman score: 2872; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:1-431) 10 20 30 40 50 60 pF1KSD MMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIVSSYASKVCFEIEEDYKNRQFLGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIVSSYASKVCFEIEEDYKNRQFLGPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLVRDEVTVTIAFGSWSQHLALDLQHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLVRDEVTVTIAFGSWSQHLALDLQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQGEVDVSWFLVAHFKNEGMVLEHPARVEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQGEVDVSWFLVAHFKNEGMVLEHPARVEP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD FYAVLESPSFSLMGILLRIASGTRLSIPITSNTLIYYHPHPEDIKFHLYLVPSDALLTKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FYAVLESPSFSLMGILLRIASGTRLSIPITSNTLIYYHPHPEDIKFHLYLVPSDALLTKA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD IDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSANLKVMPKELKLSYRSPGEIQHFSKFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSANLKVMPKELKLSYRSPGEIQHFSKFY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVAASAPPPFSGAAFVKENHRQLQARMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVAASAPPPFSGAAFVKENHRQLQARMG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLALDVLFRSISERDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLALDVLFRSISERDP 370 380 390 400 410 420 430 pF1KSD YLVSYLRQQNL ::::::::::: XP_006 YLVSYLRQQNL 430 >>XP_016881975 (OMIM: 609051) PREDICTED: caspase recruit (455 aa) initn: 2872 init1: 2872 opt: 2872 Z-score: 3272.4 bits: 614.7 E(85289): 1.6e-175 Smith-Waterman score: 2872; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:25-455) 10 20 30 pF1KSD MMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIV :::::::::::::::::::::::::::::::::::: XP_016 MIRYTGSYPVFLRPFVTSHIFSKKMMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD SSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD RDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQGEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQGEVD 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD VSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLIY 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD YHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSANL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD KVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVAA 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD SAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEAL 370 380 390 400 410 420 400 410 420 430 pF1KSD LSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL ::::::::::::::::::::::::::::::::::: XP_016 LSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL 430 440 450 >>XP_011524950 (OMIM: 609051) PREDICTED: caspase recruit (463 aa) initn: 2872 init1: 2872 opt: 2872 Z-score: 3272.3 bits: 614.7 E(85289): 1.6e-175 Smith-Waterman score: 2872; 100.0% identity (100.0% similar) in 431 aa overlap (1-431:33-463) 10 20 30 pF1KSD MMRQRQSHYCSVLFLSVNYLGGTFPGDICS :::::::::::::::::::::::::::::: XP_011 IHKKQRHAGYTGSYPVFLRPFVTSHIFSKKMMRQRQSHYCSVLFLSVNYLGGTFPGDICS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD EENQIVSSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EENQIVSSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSAT 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD GLGFLVRDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLGFLVRDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFIS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD LQGEVDVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQGEVDVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPIT 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD SNTLIYYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNTLIYYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYIV 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD SNSANLKVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SNSANLKVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPVD 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD LQLVAASAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQLVAASAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQ 370 380 390 400 410 420 400 410 420 430 pF1KSD SKNEALLSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL ::::::::::::::::::::::::::::::::::::::::: XP_011 SKNEALLSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL 430 440 450 460 >>XP_006723164 (OMIM: 609051) PREDICTED: caspase recruit (432 aa) initn: 2858 init1: 1823 opt: 2860 Z-score: 3259.1 bits: 612.1 E(85289): 8.6e-175 Smith-Waterman score: 2860; 99.8% identity (99.8% similar) in 432 aa overlap (1-431:1-432) 10 20 30 40 50 60 pF1KSD MMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIVSSYASKVCFEIEEDYKNRQFLGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIVSSYASKVCFEIEEDYKNRQFLGPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLVRDEVTVTIAFGSWSQHLALDLQHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLVRDEVTVTIAFGSWSQHLALDLQHH 70 80 90 100 110 120 130 140 150 160 170 pF1KSD EQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQ-GEVDVSWFLVAHFKNEGMVLEHPARVE :::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::: XP_006 EQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQAGEVDVSWFLVAHFKNEGMVLEHPARVE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD PFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLIYYHPHPEDIKFHLYLVPSDALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLIYYHPHPEDIKFHLYLVPSDALLTK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD AIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSANLKVMPKELKLSYRSPGEIQHFSKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSANLKVMPKELKLSYRSPGEIQHFSKF 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD YAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVAASAPPPFSGAAFVKENHRQLQARM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVAASAPPPFSGAAFVKENHRQLQARM 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD GDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLALDVLFRSISERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLALDVLFRSISERD 370 380 390 400 410 420 420 430 pF1KSD PYLVSYLRQQNL :::::::::::: XP_006 PYLVSYLRQQNL 430 >>XP_006723165 (OMIM: 609051) PREDICTED: caspase recruit (432 aa) initn: 2858 init1: 1823 opt: 2860 Z-score: 3259.1 bits: 612.1 E(85289): 8.6e-175 Smith-Waterman score: 2860; 99.8% identity (99.8% similar) in 432 aa overlap (1-431:1-432) 10 20 30 40 50 60 pF1KSD MMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIVSSYASKVCFEIEEDYKNRQFLGPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIVSSYASKVCFEIEEDYKNRQFLGPE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLVRDEVTVTIAFGSWSQHLALDLQHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLVRDEVTVTIAFGSWSQHLALDLQHH 70 80 90 100 110 120 130 140 150 160 170 pF1KSD EQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQ-GEVDVSWFLVAHFKNEGMVLEHPARVE :::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::: XP_006 EQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQAGEVDVSWFLVAHFKNEGMVLEHPARVE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KSD PFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLIYYHPHPEDIKFHLYLVPSDALLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLIYYHPHPEDIKFHLYLVPSDALLTK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KSD AIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSANLKVMPKELKLSYRSPGEIQHFSKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSANLKVMPKELKLSYRSPGEIQHFSKF 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD YAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVAASAPPPFSGAAFVKENHRQLQARM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVAASAPPPFSGAAFVKENHRQLQARM 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD GDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLALDVLFRSISERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLALDVLFRSISERD 370 380 390 400 410 420 420 430 pF1KSD PYLVSYLRQQNL :::::::::::: XP_006 PYLVSYLRQQNL 430 >>XP_006723161 (OMIM: 609051) PREDICTED: caspase recruit (456 aa) initn: 2858 init1: 1823 opt: 2860 Z-score: 3258.7 bits: 612.1 E(85289): 9e-175 Smith-Waterman score: 2860; 99.8% identity (99.8% similar) in 432 aa overlap (1-431:25-456) 10 20 30 pF1KSD MMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIV :::::::::::::::::::::::::::::::::::: XP_006 MIRYTGSYPVFLRPFVTSHIFSKKMMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD SSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD RDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQ-GEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_006 RDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQAGEV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD DVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLI 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD YYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSAN 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD LKVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVA 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD ASAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEA 370 380 390 400 410 420 400 410 420 430 pF1KSD LLSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL :::::::::::::::::::::::::::::::::::: XP_006 LLSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL 430 440 450 >>XP_006723162 (OMIM: 609051) PREDICTED: caspase recruit (456 aa) initn: 2858 init1: 1823 opt: 2860 Z-score: 3258.7 bits: 612.1 E(85289): 9e-175 Smith-Waterman score: 2860; 99.8% identity (99.8% similar) in 432 aa overlap (1-431:25-456) 10 20 30 pF1KSD MMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIV :::::::::::::::::::::::::::::::::::: XP_006 MIRYTGSYPVFLRPFVTSHIFSKKMMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIV 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD SSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD RDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQ-GEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_006 RDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQAGEV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD DVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLI 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD YYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSAN 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD LKVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVA 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD ASAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEA 370 380 390 400 410 420 400 410 420 430 pF1KSD LLSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL :::::::::::::::::::::::::::::::::::: XP_006 LLSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL 430 440 450 >>XP_011524949 (OMIM: 609051) PREDICTED: caspase recruit (464 aa) initn: 2858 init1: 1823 opt: 2860 Z-score: 3258.6 bits: 612.1 E(85289): 9.1e-175 Smith-Waterman score: 2860; 99.8% identity (99.8% similar) in 432 aa overlap (1-431:33-464) 10 20 30 pF1KSD MMRQRQSHYCSVLFLSVNYLGGTFPGDICS :::::::::::::::::::::::::::::: XP_011 IHKKQRHAGYTGSYPVFLRPFVTSHIFSKKMMRQRQSHYCSVLFLSVNYLGGTFPGDICS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD EENQIVSSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EENQIVSSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSAT 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD GLGFLVRDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLGFLVRDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFIS 130 140 150 160 170 180 160 170 180 190 200 pF1KSD LQ-GEVDVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPI :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQAGEVDVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPI 190 200 210 220 230 240 210 220 230 240 250 260 pF1KSD TSNTLIYYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSNTLIYYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYI 250 260 270 280 290 300 270 280 290 300 310 320 pF1KSD VSNSANLKVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSNSANLKVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPV 310 320 330 340 350 360 330 340 350 360 370 380 pF1KSD DLQLVAASAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLQLVAASAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTR 370 380 390 400 410 420 390 400 410 420 430 pF1KSD QSKNEALLSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL :::::::::::::::::::::::::::::::::::::::::: XP_011 QSKNEALLSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL 430 440 450 460 >>XP_011524948 (OMIM: 609051) PREDICTED: caspase recruit (464 aa) initn: 2858 init1: 1823 opt: 2860 Z-score: 3258.6 bits: 612.1 E(85289): 9.1e-175 Smith-Waterman score: 2860; 99.8% identity (99.8% similar) in 432 aa overlap (1-431:33-464) 10 20 30 pF1KSD MMRQRQSHYCSVLFLSVNYLGGTFPGDICS :::::::::::::::::::::::::::::: XP_011 IHKKQRHAGYTGSYPVFLRPFVTSHIFSKKMMRQRQSHYCSVLFLSVNYLGGTFPGDICS 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD EENQIVSSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EENQIVSSYASKVCFEIEEDYKNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSAT 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD GLGFLVRDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLGFLVRDEVTVTIAFGSWSQHLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFIS 130 140 150 160 170 180 160 170 180 190 200 pF1KSD LQ-GEVDVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPI :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQAGEVDVSWFLVAHFKNEGMVLEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPI 190 200 210 220 230 240 210 220 230 240 250 260 pF1KSD TSNTLIYYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSNTLIYYHPHPEDIKFHLYLVPSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYI 250 260 270 280 290 300 270 280 290 300 310 320 pF1KSD VSNSANLKVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSNSANLKVMPKELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPV 310 320 330 340 350 360 330 340 350 360 370 380 pF1KSD DLQLVAASAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DLQLVAASAPPPFSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTR 370 380 390 400 410 420 390 400 410 420 430 pF1KSD QSKNEALLSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL :::::::::::::::::::::::::::::::::::::::::: XP_011 QSKNEALLSMVEKKGDLALDVLFRSISERDPYLVSYLRQQNL 430 440 450 460 >>XP_016881973 (OMIM: 609051) PREDICTED: caspase recruit (486 aa) initn: 2697 init1: 2697 opt: 2698 Z-score: 3073.9 bits: 578.0 E(85289): 1.8e-164 Smith-Waterman score: 2698; 99.3% identity (99.3% similar) in 410 aa overlap (22-431:77-486) 10 20 30 40 50 pF1KSD MMRQRQSHYCSVLFLSVNYLGGTFPGDICSEENQIVSSYASKVCFEIEEDY : :::::::::::::::::::::::::: XP_016 AEPLLFRAVPECQLSGGDIPSVSEEQESSEGQDSGDICSEENQIVSSYASKVCFEIEEDY 50 60 70 80 90 100 60 70 80 90 100 110 pF1KSD KNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLVRDEVTVTIAFGSWSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNRQFLGPEGNVDVELIDKSTNRYSVWFPTAGWYLWSATGLGFLVRDEVTVTIAFGSWSQ 110 120 130 140 150 160 120 130 140 150 160 170 pF1KSD HLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQGEVDVSWFLVAHFKNEGMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLALDLQHHEQWLVGGPLFDVTAEPEEAVAEIHLPHFISLQGEVDVSWFLVAHFKNEGMV 170 180 190 200 210 220 180 190 200 210 220 230 pF1KSD LEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLIYYHPHPEDIKFHLYLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEHPARVEPFYAVLESPSFSLMGILLRIASGTRLSIPITSNTLIYYHPHPEDIKFHLYLV 230 240 250 260 270 280 240 250 260 270 280 290 pF1KSD PSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSANLKVMPKELKLSYRSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSDALLTKAIDDEEDRFHGVRLQTSPPMEPLNFGSSYIVSNSANLKVMPKELKLSYRSPG 290 300 310 320 330 340 300 310 320 330 340 350 pF1KSD EIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVAASAPPPFSGAAFVKEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIQHFSKFYAGQMKEPIQLEITEKRHGTLVWDTEVKPVDLQLVAASAPPPFSGAAFVKEN 350 360 370 380 390 400 360 370 380 390 400 410 pF1KSD HRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLALDVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLALDVL 410 420 430 440 450 460 420 430 pF1KSD FRSISERDPYLVSYLRQQNL :::::::::::::::::::: XP_016 FRSISERDPYLVSYLRQQNL 470 480 431 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:23:02 2016 done: Thu Nov 3 04:23:03 2016 Total Scan time: 8.930 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]