Result of FASTA (omim) for pF1KSDA0957
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0957, 692 aa
  1>>>pF1KSDA0957 692 - 692 aa - 692 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.8574+/-0.000455; mu= 4.2472+/- 0.028
 mean_var=254.7418+/-53.246, 0's: 0 Z-trim(119.6): 674  B-trim: 1017 in 1/52
 Lambda= 0.080357
 statistics sampled from 33001 (33805) to 33001 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.396), width:  16
 Scan time:  9.610

The best scores are:                                      opt bits E(85289)
NP_001229742 (OMIM: 610583) ankyrin repeat domain- ( 692) 4525 538.4 3.4e-152
XP_016865987 (OMIM: 610583) PREDICTED: ankyrin rep ( 687) 4476 532.7 1.7e-150
XP_016865982 (OMIM: 610583) PREDICTED: ankyrin rep ( 717) 4064 485.0 4.3e-136
XP_016865984 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 4029 480.9  7e-135
XP_016865986 (OMIM: 610583) PREDICTED: ankyrin rep ( 689) 3980 475.2 3.5e-133
XP_016865994 (OMIM: 610583) PREDICTED: ankyrin rep ( 659) 3784 452.5 2.4e-126
XP_011533901 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 3757 449.4 2.2e-125
XP_016865991 (OMIM: 610583) PREDICTED: ankyrin rep ( 661) 3586 429.5 1.9e-119
XP_011533898 (OMIM: 610583) PREDICTED: ankyrin rep ( 719) 3568 427.5 8.7e-119
XP_016865983 (OMIM: 610583) PREDICTED: ankyrin rep ( 714) 3519 421.8 4.5e-117
XP_016865993 (OMIM: 610583) PREDICTED: ankyrin rep ( 659) 3505 420.1 1.3e-116
XP_016865985 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 3433 411.8 4.4e-114
XP_011533900 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 3433 411.8 4.4e-114
XP_016865988 (OMIM: 610583) PREDICTED: ankyrin rep ( 684) 3410 409.1 2.8e-113
XP_016865998 (OMIM: 610583) PREDICTED: ankyrin rep ( 626) 3372 404.7 5.5e-112
XP_016866000 (OMIM: 610583) PREDICTED: ankyrin rep ( 593) 3328 399.6 1.8e-110
XP_016865999 (OMIM: 610583) PREDICTED: ankyrin rep ( 593) 3328 399.6 1.8e-110
XP_016865992 (OMIM: 610583) PREDICTED: ankyrin rep ( 661) 3314 398.0  6e-110
XP_011533899 (OMIM: 610583) PREDICTED: ankyrin rep ( 719) 3296 396.0 2.7e-109
XP_016865996 (OMIM: 610583) PREDICTED: ankyrin rep ( 656) 3239 389.3 2.5e-107
NP_001229740 (OMIM: 610583) ankyrin repeat domain- ( 727) 3229 388.2  6e-107
NP_001229738 (OMIM: 610583) ankyrin repeat domain- ( 727) 3229 388.2  6e-107
XP_005248738 (OMIM: 610583) PREDICTED: ankyrin rep ( 727) 3229 388.2  6e-107
XP_005248736 (OMIM: 610583) PREDICTED: ankyrin rep ( 752) 3208 385.8 3.3e-106
XP_016865990 (OMIM: 610583) PREDICTED: ankyrin rep ( 661) 3162 380.4 1.2e-104
XP_005248737 (OMIM: 610583) PREDICTED: ankyrin rep ( 747) 3159 380.1 1.7e-104
XP_016865995 (OMIM: 610583) PREDICTED: ankyrin rep ( 656) 3113 374.7 6.2e-103
XP_016865997 (OMIM: 610583) PREDICTED: ankyrin rep ( 628) 3083 371.2 6.7e-102
XP_005248740 (OMIM: 610583) PREDICTED: ankyrin rep ( 686) 3067 369.4 2.6e-101
XP_016865989 (OMIM: 610583) PREDICTED: ankyrin rep ( 681) 3018 363.7 1.3e-99
XP_016866002 (OMIM: 610583) PREDICTED: ankyrin rep ( 567) 2986 359.9 1.5e-98
XP_016866001 (OMIM: 610583) PREDICTED: ankyrin rep ( 567) 2986 359.9 1.5e-98
XP_005248741 (OMIM: 610583) PREDICTED: ankyrin rep ( 592) 2911 351.2 6.5e-96
XP_016866003 (OMIM: 610583) PREDICTED: ankyrin rep ( 534) 2901 350.0 1.3e-95
XP_016866004 (OMIM: 610583) PREDICTED: ankyrin rep ( 493) 2851 344.2   7e-94
XP_005248739 (OMIM: 610583) PREDICTED: ankyrin rep ( 726) 2842 343.3 1.9e-93
XP_011533902 (OMIM: 610583) PREDICTED: ankyrin rep ( 663) 2793 337.6 9.2e-92
NP_001229743 (OMIM: 610583) ankyrin repeat domain- ( 663) 2793 337.6 9.2e-92
NP_055757 (OMIM: 610583) ankyrin repeat domain-con ( 722) 1746 216.3 3.4e-55
XP_016863596 (OMIM: 106410,600919) PREDICTED: anky (1797)  466 68.3   3e-10
XP_016863595 (OMIM: 106410,600919) PREDICTED: anky (1806)  466 68.3   3e-10
XP_016863591 (OMIM: 106410,600919) PREDICTED: anky (1838)  466 68.3 3.1e-10
XP_016863589 (OMIM: 106410,600919) PREDICTED: anky (1846)  466 68.3 3.1e-10
XP_016863586 (OMIM: 106410,600919) PREDICTED: anky (1858)  466 68.3 3.1e-10
XP_016863580 (OMIM: 106410,600919) PREDICTED: anky (1879)  466 68.3 3.1e-10
XP_011517331 (OMIM: 607001,610253) PREDICTED: hist ( 775)  451 66.2 5.5e-10
NP_065210 (OMIM: 182900,612641) ankyrin-1 isoform  (1719)  456 67.1 6.5e-10
XP_011542807 (OMIM: 182900,612641) PREDICTED: anky (1751)  456 67.1 6.6e-10
XP_011542806 (OMIM: 182900,612641) PREDICTED: anky (1752)  456 67.1 6.6e-10
XP_016868818 (OMIM: 182900,612641) PREDICTED: anky (1759)  456 67.1 6.6e-10


>>NP_001229742 (OMIM: 610583) ankyrin repeat domain-cont  (692 aa)
 initn: 4525 init1: 4525 opt: 4525  Z-score: 2853.4  bits: 538.4 E(85289): 3.4e-152
Smith-Waterman score: 4525; 99.9% identity (100.0% similar) in 692 aa overlap (1-692:1-692)

               10        20        30        40        50        60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
       :::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
              610       620       630       640       650       660

              670       680       690  
pF1KSD QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
       ::::::::::::::::::::::::::::::::
NP_001 QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
              670       680       690  

>>XP_016865987 (OMIM: 610583) PREDICTED: ankyrin repeat   (687 aa)
 initn: 3274 init1: 3274 opt: 4476  Z-score: 2822.7  bits: 532.7 E(85289): 1.7e-150
Smith-Waterman score: 4476; 99.1% identity (99.3% similar) in 692 aa overlap (1-692:1-687)

               10        20        30        40        50        60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
       :::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD KLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
       ::::::::::::::::::     :::::::::::::::::::::::::::::::::::::
XP_016 KLSGDSRACRAKSTPSTC-----VDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
              490            500       510       520       530     

              550       560       570       580       590       600
pF1KSD QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
         540       550       560       570       580       590     

              610       620       630       640       650       660
pF1KSD PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
         600       610       620       630       640       650     

              670       680       690  
pF1KSD QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
       ::::::::::::::::::::::::::::::::
XP_016 QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
         660       670       680       

>>XP_016865982 (OMIM: 610583) PREDICTED: ankyrin repeat   (717 aa)
 initn: 4064 init1: 4064 opt: 4064  Z-score: 2564.3  bits: 485.0 E(85289): 4.3e-136
Smith-Waterman score: 4064; 99.4% identity (99.8% similar) in 622 aa overlap (71-692:96-717)

               50        60        70        80        90       100
pF1KSD HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA
                                     . .:::::::::::::::::::::::::::
XP_016 AVATVKAMKEDKNKKNHRGKVRKDPRRSEREKEGDQTALHRATVVGNTEIIAALIHEGCA
          70        80        90       100       110       120     

              110       120       130       140       150       160
pF1KSD LDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
       :::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 LDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
         130       140       150       160       170       180     

              170       180       190       200       210       220
pF1KSD LLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHK
         190       200       210       220       230       240     

              230       240       250       260       270       280
pF1KSD KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVA
         250       260       270       280       290       300     

              290       300       310       320       330       340
pF1KSD RKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRN
         310       320       330       340       350       360     

              350       360       370       380       390       400
pF1KSD RHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAE
         370       380       390       400       410       420     

              410       420       430       440       450       460
pF1KSD LGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQ
         430       440       450       460       470       480     

              470       480       490       500       510       520
pF1KSD ISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSS
         490       500       510       520       530       540     

              530       540       550       560       570       580
pF1KSD PPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVN
         550       560       570       580       590       600     

              590       600       610       620       630       640
pF1KSD RGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAV
         610       620       630       640       650       660     

              650       660       670       680       690  
pF1KSD STQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
         670       680       690       700       710       

>>XP_016865984 (OMIM: 610583) PREDICTED: ankyrin repeat   (694 aa)
 initn: 4055 init1: 2842 opt: 4029  Z-score: 2542.6  bits: 480.9 E(85289): 7e-135
Smith-Waterman score: 4149; 90.5% identity (90.6% similar) in 727 aa overlap (1-692:1-694)

               10        20        30        40        50        60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
       :::::::.::::::::::::::::::::::::::::::::::::::::::::::::    
XP_016 SQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDT----
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
                                    :::::::::::::::::::::::::::::::
XP_016 -----------------------------ALHVAAALNHKKVAKILLEAGADTTIVNNAG
                                     180       190       200       

              250       260                                        
pF1KSD QTPLETARYHNNPEVALLLTKAPQ-----------------------------------G
       ::::::::::::::::::::::::                                   :
XP_016 QTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKG
       210       220       230       240       250       260       

         270       280       290       300       310       320     
pF1KSD SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
       270       280       290       300       310       320       

         330       340       350       360       370       380     
pF1KSD HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
       330       340       350       360       370       380       

         390       400       410       420       430       440     
pF1KSD LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
       390       400       410       420       430       440       

         450       460       470       480       490       500     
pF1KSD QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
       450       460       470       480       490       500       

         510       520       530       540       550       560     
pF1KSD QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
       510       520       530       540       550       560       

         570       580       590       600       610       620     
pF1KSD NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
       570       580       590       600       610       620       

         630       640       650       660       670       680     
pF1KSD TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
       630       640       650       660       670       680       

         690  
pF1KSD TRVQKEN
       :::::::
XP_016 TRVQKEN
       690    

>>XP_016865986 (OMIM: 610583) PREDICTED: ankyrin repeat   (689 aa)
 initn: 2804 init1: 1591 opt: 3980  Z-score: 2511.9  bits: 475.2 E(85289): 3.5e-133
Smith-Waterman score: 4100; 89.8% identity (90.0% similar) in 727 aa overlap (1-692:1-689)

               10        20        30        40        50        60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
       :::::::.::::::::::::::::::::::::::::::::::::::::::::::::    
XP_016 SQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDT----
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
                                    :::::::::::::::::::::::::::::::
XP_016 -----------------------------ALHVAAALNHKKVAKILLEAGADTTIVNNAG
                                     180       190       200       

              250       260                                        
pF1KSD QTPLETARYHNNPEVALLLTKAPQ-----------------------------------G
       ::::::::::::::::::::::::                                   :
XP_016 QTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKG
       210       220       230       240       250       260       

         270       280       290       300       310       320     
pF1KSD SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
       270       280       290       300       310       320       

         330       340       350       360       370       380     
pF1KSD HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
       330       340       350       360       370       380       

         390       400       410       420       430       440     
pF1KSD LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
       390       400       410       420       430       440       

         450       460       470       480       490       500     
pF1KSD QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
       :::::::::::::::::::::::::::::::::::::::::::::::::::::     ::
XP_016 QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTC-----VD
       450       460       470       480       490       500       

         510       520       530       540       550       560     
pF1KSD QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
            510       520       530       540       550       560  

         570       580       590       600       610       620     
pF1KSD NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
            570       580       590       600       610       620  

         630       640       650       660       670       680     
pF1KSD TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
            630       640       650       660       670       680  

         690  
pF1KSD TRVQKEN
       :::::::
XP_016 TRVQKEN
              

>>XP_016865994 (OMIM: 610583) PREDICTED: ankyrin repeat   (659 aa)
 initn: 3756 init1: 3756 opt: 3784  Z-score: 2389.4  bits: 452.5 E(85289): 2.4e-126
Smith-Waterman score: 4237; 95.2% identity (95.2% similar) in 692 aa overlap (1-692:1-659)

               10        20        30        40        50        60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
       ::::::::::::::::::::::::::::::::::::::::::::::              
XP_016 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDK--------------
               70        80        90       100                    

              130       140       150       160       170       180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
                          :::::::::::::::::::::::::::::::::::::::::
XP_016 -------------------AGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
                           110       120       130       140       

              190       200       210       220       230       240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
       150       160       170       180       190       200       

              250       260       270       280       290       300
pF1KSD QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
       210       220       230       240       250       260       

              310       320       330       340       350       360
pF1KSD DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
       270       280       290       300       310       320       

              370       380       390       400       410       420
pF1KSD LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
       330       340       350       360       370       380       

              430       440       450       460       470       480
pF1KSD HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
       390       400       410       420       430       440       

              490       500       510       520       530       540
pF1KSD KLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
       450       460       470       480       490       500       

              550       560       570       580       590       600
pF1KSD QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
       510       520       530       540       550       560       

              610       620       630       640       650       660
pF1KSD PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
       570       580       590       600       610       620       

              670       680       690  
pF1KSD QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
       ::::::::::::::::::::::::::::::::
XP_016 QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
       630       640       650         

>>XP_011533901 (OMIM: 610583) PREDICTED: ankyrin repeat   (694 aa)
 initn: 3783 init1: 2842 opt: 3757  Z-score: 2372.2  bits: 449.4 E(85289): 2.2e-125
Smith-Waterman score: 4157; 90.6% identity (90.6% similar) in 727 aa overlap (1-692:1-694)

               10        20        30        40        50        60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
       ::::::::::::::::::::::::::::::::::::::::::::::              
XP_011 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDK--------------
               70        80        90       100                    

              130       140       150       160       170       180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
                          :::::::::::::::::::::::::::::::::::::::::
XP_011 -------------------AGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
                           110       120       130       140       

              190       200       210       220       230       240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
       150       160       170       180       190       200       

              250       260                                        
pF1KSD QTPLETARYHNNPEVALLLTKAPQ-----------------------------------G
       ::::::::::::::::::::::::                                   :
XP_011 QTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKG
       210       220       230       240       250       260       

         270       280       290       300       310       320     
pF1KSD SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
       270       280       290       300       310       320       

         330       340       350       360       370       380     
pF1KSD HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
       330       340       350       360       370       380       

         390       400       410       420       430       440     
pF1KSD LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
       390       400       410       420       430       440       

         450       460       470       480       490       500     
pF1KSD QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
       450       460       470       480       490       500       

         510       520       530       540       550       560     
pF1KSD QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
       510       520       530       540       550       560       

         570       580       590       600       610       620     
pF1KSD NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
       570       580       590       600       610       620       

         630       640       650       660       670       680     
pF1KSD TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
       630       640       650       660       670       680       

         690  
pF1KSD TRVQKEN
       :::::::
XP_011 TRVQKEN
       690    

>>XP_016865991 (OMIM: 610583) PREDICTED: ankyrin repeat   (661 aa)
 initn: 3591 init1: 2842 opt: 3586  Z-score: 2265.3  bits: 429.5 E(85289): 1.9e-119
Smith-Waterman score: 3844; 86.0% identity (86.1% similar) in 727 aa overlap (1-692:1-661)

               10        20        30        40        50        60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
       ::::::::::::::::::::::::::::::::::::::::                    
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTK--------------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
                    :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -------------GDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
                            50        60        70        80       

              130       140       150       160       170       180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
       :::::::.::::::::::::::::::::::::::::::::::::::::::::::::    
XP_016 SQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDT----
        90       100       110       120       130       140       

              190       200       210       220       230       240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
                                    :::::::::::::::::::::::::::::::
XP_016 -----------------------------ALHVAAALNHKKVAKILLEAGADTTIVNNAG
                                        150       160       170    

              250       260                                        
pF1KSD QTPLETARYHNNPEVALLLTKAPQ-----------------------------------G
       ::::::::::::::::::::::::                                   :
XP_016 QTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKG
          180       190       200       210       220       230    

         270       280       290       300       310       320     
pF1KSD SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
          240       250       260       270       280       290    

         330       340       350       360       370       380     
pF1KSD HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
          300       310       320       330       340       350    

         390       400       410       420       430       440     
pF1KSD LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
          360       370       380       390       400       410    

         450       460       470       480       490       500     
pF1KSD QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
          420       430       440       450       460       470    

         510       520       530       540       550       560     
pF1KSD QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
          480       490       500       510       520       530    

         570       580       590       600       610       620     
pF1KSD NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
          540       550       560       570       580       590    

         630       640       650       660       670       680     
pF1KSD TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
          600       610       620       630       640       650    

         690  
pF1KSD TRVQKEN
       :::::::
XP_016 TRVQKEN
          660 

>>XP_011533898 (OMIM: 610583) PREDICTED: ankyrin repeat   (719 aa)
 initn: 3594 init1: 2842 opt: 3568  Z-score: 2253.6  bits: 427.5 E(85289): 8.7e-119
Smith-Waterman score: 3688; 89.0% identity (89.5% similar) in 657 aa overlap (71-692:96-719)

               50        60        70        80        90       100
pF1KSD HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA
                                     . .:::::::::::::::::::::::::::
XP_011 AVATVKAMKEDKNKKNHRGKVRKDPRRSEREKEGDQTALHRATVVGNTEIIAALIHEGCA
          70        80        90       100       110       120     

              110       120       130       140       150       160
pF1KSD LDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
       :::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_011 LDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
         130       140       150       160       170       180     

              170       180       190       200       210       220
pF1KSD LLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHK
       ::::::::::::::::                                 :::::::::::
XP_011 LLAGSRADLKNNAGDT---------------------------------ALHVAAALNHK
         190       200                                        210  

              230       240       250       260                    
pF1KSD KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQ----------------
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_011 KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRER
            220       230       240       250       260       270  

                             270       280       290       300     
pF1KSD -------------------GSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRK
                          :::::::::::::::::::::::::::::::::::::::::
XP_011 LKEERRAQSVPRDEVAQSKGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRK
            280       290       300       310       320       330  

         310       320       330       340       350       360     
pF1KSD SRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGK
            340       350       360       370       380       390  

         370       380       390       400       410       420     
pF1KSD DGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRV
            400       410       420       430       440       450  

         430       440       450       460       470       480     
pF1KSD LDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGD
            460       470       480       490       500       510  

         490       500       510       520       530       540     
pF1KSD SRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSS
            520       530       540       550       560       570  

         550       560       570       580       590       600     
pF1KSD SDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASS
            580       590       600       610       620       630  

         610       620       630       640       650       660     
pF1KSD TCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQ
            640       650       660       670       680       690  

         670       680       690  
pF1KSD DKATLKEHIKSLEEELAKLRTRVQKEN
       :::::::::::::::::::::::::::
XP_011 DKATLKEHIKSLEEELAKLRTRVQKEN
            700       710         

>>XP_016865983 (OMIM: 610583) PREDICTED: ankyrin repeat   (714 aa)
 initn: 2343 init1: 1591 opt: 3519  Z-score: 2222.9  bits: 421.8 E(85289): 4.5e-117
Smith-Waterman score: 3639; 88.3% identity (88.7% similar) in 657 aa overlap (71-692:96-714)

               50        60        70        80        90       100
pF1KSD HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA
                                     . .:::::::::::::::::::::::::::
XP_016 AVATVKAMKEDKNKKNHRGKVRKDPRRSEREKEGDQTALHRATVVGNTEIIAALIHEGCA
          70        80        90       100       110       120     

              110       120       130       140       150       160
pF1KSD LDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
       :::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 LDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
         130       140       150       160       170       180     

              170       180       190       200       210       220
pF1KSD LLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHK
       ::::::::::::::::                                 :::::::::::
XP_016 LLAGSRADLKNNAGDT---------------------------------ALHVAAALNHK
         190       200                                        210  

              230       240       250       260                    
pF1KSD KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQ----------------
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_016 KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRER
            220       230       240       250       260       270  

                             270       280       290       300     
pF1KSD -------------------GSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRK
                          :::::::::::::::::::::::::::::::::::::::::
XP_016 LKEERRAQSVPRDEVAQSKGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRK
            280       290       300       310       320       330  

         310       320       330       340       350       360     
pF1KSD SRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGK
            340       350       360       370       380       390  

         370       380       390       400       410       420     
pF1KSD DGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRV
            400       410       420       430       440       450  

         430       440       450       460       470       480     
pF1KSD LDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGD
            460       470       480       490       500       510  

         490       500       510       520       530       540     
pF1KSD SRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSS
       :::::::::::::     ::::::::::::::::::::::::::::::::::::::::::
XP_016 SRACRAKSTPSTC-----VDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSS
            520            530       540       550       560       

         550       560       570       580       590       600     
pF1KSD SDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASS
       570       580       590       600       610       620       

         610       620       630       640       650       660     
pF1KSD TCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQ
       630       640       650       660       670       680       

         670       680       690  
pF1KSD DKATLKEHIKSLEEELAKLRTRVQKEN
       :::::::::::::::::::::::::::
XP_016 DKATLKEHIKSLEEELAKLRTRVQKEN
       690       700       710    




692 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 04:24:12 2016 done: Thu Nov  3 04:24:13 2016
 Total Scan time:  9.610 Total Display time:  0.160

Function used was FASTA [36.3.4 Apr, 2011]
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