FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0958, 424 aa 1>>>pF1KSDA0958 424 - 424 aa - 424 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7516+/-0.000373; mu= 20.8961+/- 0.023 mean_var=69.9391+/-14.259, 0's: 0 Z-trim(114.1): 26 B-trim: 0 in 0/50 Lambda= 0.153361 statistics sampled from 23696 (23719) to 23696 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.278), width: 16 Scan time: 9.050 The best scores are: opt bits E(85289) NP_056042 (OMIM: 610249) GDP-fucose protein O-fuco ( 424) 2940 659.6 4.1e-189 NP_598368 (OMIM: 610249) GDP-fucose protein O-fuco ( 429) 2624 589.7 4.6e-168 XP_006724044 (OMIM: 610249) PREDICTED: GDP-fucose ( 449) 1749 396.1 9.1e-110 XP_011527807 (OMIM: 610249) PREDICTED: GDP-fucose ( 488) 1413 321.8 2.3e-87 XP_011527812 (OMIM: 610249) PREDICTED: GDP-fucose ( 267) 1404 319.6 5.9e-87 XP_011527808 (OMIM: 610249) PREDICTED: GDP-fucose ( 474) 1404 319.8 9e-87 XP_011527806 (OMIM: 610249) PREDICTED: GDP-fucose ( 494) 1404 319.9 9.3e-87 XP_016883795 (OMIM: 610249) PREDICTED: GDP-fucose ( 419) 1253 286.4 9.4e-77 XP_011527809 (OMIM: 610249) PREDICTED: GDP-fucose ( 439) 1253 286.4 9.7e-77 XP_016883798 (OMIM: 610249) PREDICTED: GDP-fucose ( 214) 1137 260.4 3.1e-69 XP_011527815 (OMIM: 610249) PREDICTED: GDP-fucose ( 212) 879 203.4 4.6e-52 XP_016883797 (OMIM: 610249) PREDICTED: GDP-fucose ( 225) 879 203.4 4.8e-52 XP_011527813 (OMIM: 610249) PREDICTED: GDP-fucose ( 251) 879 203.4 5.3e-52 XP_011527814 (OMIM: 610249) PREDICTED: GDP-fucose ( 251) 879 203.4 5.3e-52 XP_016883796 (OMIM: 610249) PREDICTED: GDP-fucose ( 280) 879 203.5 5.7e-52 XP_011527811 (OMIM: 610249) PREDICTED: GDP-fucose ( 301) 879 203.5 6e-52 XP_011527810 (OMIM: 610249) PREDICTED: GDP-fucose ( 344) 879 203.6 6.6e-52 >>NP_056042 (OMIM: 610249) GDP-fucose protein O-fucosylt (424 aa) initn: 2940 init1: 2940 opt: 2940 Z-score: 3516.1 bits: 659.6 E(85289): 4.1e-189 Smith-Waterman score: 2940; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424) 10 20 30 40 50 60 pF1KSD MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EYEQFIAESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCIDQLLYSQDKHEYYRGWFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EYEQFIAESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCIDQLLYSQDKHEYYRGWFW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LYKDGGVAIIDQWICAHARCLPTSLSAESGSGGFQRFFCPKYSVSEQMVACVHSGHFHTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LYKDGGVAIIDQWICAHARCLPTSLSAESGSGGFQRFFCPKYSVSEQMVACVHSGHFHTV 370 380 390 400 410 420 pF1KSD CLLV :::: NP_056 CLLV >>NP_598368 (OMIM: 610249) GDP-fucose protein O-fucosylt (429 aa) initn: 2620 init1: 2620 opt: 2624 Z-score: 3138.2 bits: 589.7 E(85289): 4.6e-168 Smith-Waterman score: 2624; 98.2% identity (99.0% similar) in 390 aa overlap (1-389:1-390) 10 20 30 40 50 60 pF1KSD MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EYEQFIAESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCIDQLLYSQDKHEYYRGWFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 EYEQFIAESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCIDQLLYSQDKHEYYRGWFW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 GYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 VFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 GHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELE 310 320 330 340 350 360 370 380 390 400 410 pF1KSD LYKDGGVAIIDQWICAHARC-LPTSLSAESGSGGFQRFFCPKYSVSEQMVACVHSGHFHT ::::::::::::::::::: . ::.:. : NP_598 LYKDGGVAIIDQWICAHARFFIGTSVSTFSFRIHEEREILGLDPKTTYNRFCGDQEKACE 370 380 390 400 410 420 >>XP_006724044 (OMIM: 610249) PREDICTED: GDP-fucose prot (449 aa) initn: 2606 init1: 1745 opt: 1749 Z-score: 2091.7 bits: 396.1 E(85289): 9.1e-110 Smith-Waterman score: 2574; 93.4% identity (94.1% similar) in 410 aa overlap (1-389:1-410) 10 20 30 40 50 60 pF1KSD MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI 70 80 90 100 110 120 130 140 150 160 pF1KSD EYEQFIA--------------------ESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERP ::::::: ::::::::::::::::::::::::::::::::: XP_006 EYEQFIAGRRTACGVCFVVSQCSARDKESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERP 130 140 150 160 170 180 170 180 190 200 210 220 pF1KSD CIDQLLYSQDKHEYYRGWFWGYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CIDQLLYSQDKHEYYRGWFWGYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRA 190 200 210 220 230 240 230 240 250 260 270 280 pF1KSD ENLLHDHYGGKEYWDTRRSMVFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ENLLHDHYGGKEYWDTRRSMVFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KSD GSALGGPYLGVHLRRKDFIWGHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSALGGPYLGVHLRRKDFIWGHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYE 310 320 330 340 350 360 350 360 370 380 390 pF1KSD ELKKLLPEMVRFEPTWEELELYKDGGVAIIDQWICAHARC-LPTSLSAESGSGGFQRFFC ::::::::::::::::::::::::::::::::::::::: . ::.:. : XP_006 ELKKLLPEMVRFEPTWEELELYKDGGVAIIDQWICAHARFFIGTSVSTFSFRIHEEREIL 370 380 390 400 410 420 400 410 420 pF1KSD PKYSVSEQMVACVHSGHFHTVCLLV XP_006 GLDPKTTYNRFCGDQEKACEQPTHWKITY 430 440 >>XP_011527807 (OMIM: 610249) PREDICTED: GDP-fucose prot (488 aa) initn: 2274 init1: 1413 opt: 1413 Z-score: 1689.4 bits: 321.8 E(85289): 2.3e-87 Smith-Waterman score: 2258; 84.2% identity (84.2% similar) in 412 aa overlap (34-380:34-445) 10 20 30 40 50 60 pF1KSD LSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRRDVY :::::::::::::::::::::::::::::: XP_011 LSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRRDVY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVIEYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVIEYE 70 80 90 100 110 120 130 140 150 160 pF1KSD QFIA--------------------ESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCID :::: :::::::::::::::::::::::::::::::::::: XP_011 QFIAGRRTACGVCFVVSQCSARDKESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCID 130 140 150 160 170 180 170 pF1KSD QLLYSQDKHEYYR---------------------------------------------GW ::::::::::::: :: XP_011 QLLYSQDKHEYYRDGGLVSPKCRLPLKALTLPGLLWKSCQLTASMCPVPGQLALKHGRGW 190 200 210 220 230 240 180 190 200 210 220 230 pF1KSD FWGYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FWGYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRR 250 260 270 280 290 300 240 250 260 270 280 290 pF1KSD SMVFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMVFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDF 310 320 330 340 350 360 300 310 320 330 340 350 pF1KSD IWGHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IWGHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEE 370 380 390 400 410 420 360 370 380 390 400 410 pF1KSD LELYKDGGVAIIDQWICAHARCLPTSLSAESGSGGFQRFFCPKYSVSEQMVACVHSGHFH :::::::::::::::::::::: XP_011 LELYKDGGVAIIDQWICAHARCGLGILTATLAVLSPQPRKPAVGRLRTELSASCPQLREA 430 440 450 460 470 480 >-- initn: 225 init1: 225 opt: 225 Z-score: 268.9 bits: 59.0 E(85289): 3.1e-08 Smith-Waterman score: 225; 100.0% identity (100.0% similar) in 33 aa overlap (1-33:1-33) 10 20 30 40 50 60 pF1KSD MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR ::::::::::::::::::::::::::::::::: XP_011 MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI XP_011 DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI 70 80 90 100 110 120 >>XP_011527812 (OMIM: 610249) PREDICTED: GDP-fucose prot (267 aa) initn: 1400 init1: 1400 opt: 1404 Z-score: 1682.1 bits: 319.6 E(85289): 5.9e-87 Smith-Waterman score: 1404; 96.7% identity (98.1% similar) in 215 aa overlap (176-389:14-228) 150 160 170 180 190 200 pF1KSD GWKEGTWEEKVDERPCIDQLLYSQDKHEYYRGWFWGYEETRGLNVSCLSVQGSASIVAPL :::::::::::::::::::::::::::::: XP_011 MCPVPGQLALKHGRGWFWGYEETRGLNVSCLSVQGSASIVAPL 10 20 30 40 210 220 230 240 250 260 pF1KSD LLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSMVFARHLREVGDEFRSRHLNSTDDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSMVFARHLREVGDEFRSRHLNSTDDAD 50 60 70 80 90 100 270 280 290 300 310 320 pF1KSD RIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIWGHRQDVPSLEGAVRKIRSLMKTHRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIWGHRQDVPSLEGAVRKIRSLMKTHRL 110 120 130 140 150 160 330 340 350 360 370 380 pF1KSD DKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELELYKDGGVAIIDQWICAHARC-LPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::: . :: XP_011 DKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELELYKDGGVAIIDQWICAHARFFIGTS 170 180 190 200 210 220 390 400 410 420 pF1KSD LSAESGSGGFQRFFCPKYSVSEQMVACVHSGHFHTVCLLV .:. : XP_011 VSTFSFRIHEEREILGLDPKTTYNRFCGDQEKACEQPTHWKITY 230 240 250 260 >>XP_011527808 (OMIM: 610249) PREDICTED: GDP-fucose prot (474 aa) initn: 1400 init1: 1400 opt: 1404 Z-score: 1678.8 bits: 319.8 E(85289): 9e-87 Smith-Waterman score: 2448; 87.7% identity (88.4% similar) in 422 aa overlap (14-389:14-435) 10 20 30 40 50 60 pF1KSD MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI 70 80 90 100 110 120 130 140 150 160 170 pF1KSD EYEQFIAESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCIDQLLYSQDKHEYYR---- :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EYEQFIAESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCIDQLLYSQDKHEYYRDGGL 130 140 150 160 170 180 180 190 pF1KSD -----------------------------------------GWFWGYEETRGLNVSCLSV ::::::::::::::::::: XP_011 VSPKCRLPLKALTLPGLLWKSCQLTASMCPVPGQLALKHGRGWFWGYEETRGLNVSCLSV 190 200 210 220 230 240 200 210 220 230 240 250 pF1KSD QGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSMVFARHLREVGDEFRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSMVFARHLREVGDEFRS 250 260 270 280 290 300 260 270 280 290 300 310 pF1KSD RHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIWGHRQDVPSLEGAVRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIWGHRQDVPSLEGAVRK 310 320 330 340 350 360 320 330 340 350 360 370 pF1KSD IRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELELYKDGGVAIIDQWIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELELYKDGGVAIIDQWIC 370 380 390 400 410 420 380 390 400 410 420 pF1KSD AHARC-LPTSLSAESGSGGFQRFFCPKYSVSEQMVACVHSGHFHTVCLLV :::: . ::.:. : XP_011 AHARFFIGTSVSTFSFRIHEEREILGLDPKTTYNRFCGDQEKACEQPTHWKITY 430 440 450 460 470 >>XP_011527806 (OMIM: 610249) PREDICTED: GDP-fucose prot (494 aa) initn: 2261 init1: 1400 opt: 1404 Z-score: 1678.6 bits: 319.9 E(85289): 9.3e-87 Smith-Waterman score: 2249; 82.9% identity (83.6% similar) in 422 aa overlap (34-389:34-455) 10 20 30 40 50 60 pF1KSD LSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRRDVY :::::::::::::::::::::::::::::: XP_011 LSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRRDVY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD IRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVIEYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVIEYE 70 80 90 100 110 120 130 140 150 160 pF1KSD QFIA--------------------ESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCID :::: :::::::::::::::::::::::::::::::::::: XP_011 QFIAGRRTACGVCFVVSQCSARDKESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCID 130 140 150 160 170 180 170 pF1KSD QLLYSQDKHEYYR---------------------------------------------GW ::::::::::::: :: XP_011 QLLYSQDKHEYYRDGGLVSPKCRLPLKALTLPGLLWKSCQLTASMCPVPGQLALKHGRGW 190 200 210 220 230 240 180 190 200 210 220 230 pF1KSD FWGYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FWGYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRR 250 260 270 280 290 300 240 250 260 270 280 290 pF1KSD SMVFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMVFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDF 310 320 330 340 350 360 300 310 320 330 340 350 pF1KSD IWGHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IWGHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEE 370 380 390 400 410 420 360 370 380 390 400 410 pF1KSD LELYKDGGVAIIDQWICAHARC-LPTSLSAESGSGGFQRFFCPKYSVSEQMVACVHSGHF ::::::::::::::::::::: . ::.:. : XP_011 LELYKDGGVAIIDQWICAHARFFIGTSVSTFSFRIHEEREILGLDPKTTYNRFCGDQEKA 430 440 450 460 470 480 420 pF1KSD HTVCLLV XP_011 CEQPTHWKITY 490 >-- initn: 225 init1: 225 opt: 225 Z-score: 268.8 bits: 59.0 E(85289): 3.1e-08 Smith-Waterman score: 225; 100.0% identity (100.0% similar) in 33 aa overlap (1-33:1-33) 10 20 30 40 50 60 pF1KSD MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR ::::::::::::::::::::::::::::::::: XP_011 MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI XP_011 DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI 70 80 90 100 110 120 >>XP_016883795 (OMIM: 610249) PREDICTED: GDP-fucose prot (419 aa) initn: 2462 init1: 1249 opt: 1253 Z-score: 1499.0 bits: 286.4 E(85289): 9.4e-77 Smith-Waterman score: 2442; 93.8% identity (95.1% similar) in 390 aa overlap (1-389:1-380) 10 20 30 40 50 60 pF1KSD MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EYEQFIAESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCIDQLLYSQDKHEYYRGWFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::: . XP_016 EYEQFIAESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCIDQLLYSQDKHEYYRCLL- 130 140 150 160 170 190 200 210 220 230 240 pF1KSD GYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSM : : . ::::::::::::::::::::::::::::::::::::::::::::: XP_016 -----RLLPLP----QGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSM 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD VFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIW 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD GHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELE 300 310 320 330 340 350 370 380 390 400 410 pF1KSD LYKDGGVAIIDQWICAHARC-LPTSLSAESGSGGFQRFFCPKYSVSEQMVACVHSGHFHT ::::::::::::::::::: . ::.:. : XP_016 LYKDGGVAIIDQWICAHARFFIGTSVSTFSFRIHEEREILGLDPKTTYNRFCGDQEKACE 360 370 380 390 400 410 >>XP_011527809 (OMIM: 610249) PREDICTED: GDP-fucose prot (439 aa) initn: 2448 init1: 1249 opt: 1253 Z-score: 1498.7 bits: 286.4 E(85289): 9.7e-77 Smith-Waterman score: 2392; 89.3% identity (90.5% similar) in 410 aa overlap (1-389:1-400) 10 20 30 40 50 60 pF1KSD MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI 70 80 90 100 110 120 130 140 150 160 pF1KSD EYEQFIA--------------------ESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERP ::::::: ::::::::::::::::::::::::::::::::: XP_011 EYEQFIAGRRTACGVCFVVSQCSARDKESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERP 130 140 150 160 170 180 170 180 190 200 210 220 pF1KSD CIDQLLYSQDKHEYYRGWFWGYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRA :::::::::::::::: . : : . ::::::::::::::::::::::::: XP_011 CIDQLLYSQDKHEYYRCLL------RLLPLP----QGSASIVAPLLLRNTSARSVMLDRA 190 200 210 220 230 230 240 250 260 270 280 pF1KSD ENLLHDHYGGKEYWDTRRSMVFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENLLHDHYGGKEYWDTRRSMVFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKL 240 250 260 270 280 290 290 300 310 320 330 340 pF1KSD GSALGGPYLGVHLRRKDFIWGHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSALGGPYLGVHLRRKDFIWGHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYE 300 310 320 330 340 350 350 360 370 380 390 pF1KSD ELKKLLPEMVRFEPTWEELELYKDGGVAIIDQWICAHARC-LPTSLSAESGSGGFQRFFC ::::::::::::::::::::::::::::::::::::::: . ::.:. : XP_011 ELKKLLPEMVRFEPTWEELELYKDGGVAIIDQWICAHARFFIGTSVSTFSFRIHEEREIL 360 370 380 390 400 410 400 410 420 pF1KSD PKYSVSEQMVACVHSGHFHTVCLLV XP_011 GLDPKTTYNRFCGDQEKACEQPTHWKITY 420 430 >>XP_016883798 (OMIM: 610249) PREDICTED: GDP-fucose prot (214 aa) initn: 1133 init1: 1133 opt: 1137 Z-score: 1364.1 bits: 260.4 E(85289): 3.1e-69 Smith-Waterman score: 1137; 96.0% identity (97.7% similar) in 175 aa overlap (216-389:1-175) 190 200 210 220 230 240 pF1KSD RGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSMVFARH :::::::::::::::::::::::::::::: XP_016 MLDRAENLLHDHYGGKEYWDTRRSMVFARH 10 20 30 250 260 270 280 290 300 pF1KSD LREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIWGHRQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIWGHRQD 40 50 60 70 80 90 310 320 330 340 350 360 pF1KSD VPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELELYKDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELELYKDG 100 110 120 130 140 150 370 380 390 400 410 420 pF1KSD GVAIIDQWICAHARC-LPTSLSAESGSGGFQRFFCPKYSVSEQMVACVHSGHFHTVCLLV :::::::::::::: . ::.:. : XP_016 GVAIIDQWICAHARFFIGTSVSTFSFRIHEEREILGLDPKTTYNRFCGDQEKACEQPTHW 160 170 180 190 200 210 424 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:24:50 2016 done: Thu Nov 3 04:24:51 2016 Total Scan time: 9.050 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]