FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0959, 768 aa 1>>>pF1KSDA0959 768 - 768 aa - 768 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8898+/-0.000445; mu= 1.7349+/- 0.028 mean_var=154.1050+/-31.028, 0's: 0 Z-trim(114.6): 155 B-trim: 99 in 1/57 Lambda= 0.103316 statistics sampled from 24362 (24545) to 24362 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.288), width: 16 Scan time: 10.090 The best scores are: opt bits E(85289) NP_001284600 (OMIM: 605667) ral guanine nucleotide ( 768) 5021 761.1 0 XP_011507641 (OMIM: 605667) PREDICTED: ral guanine ( 803) 4960 752.0 2.2e-216 NP_055964 (OMIM: 605667) ral guanine nucleotide di ( 803) 4960 752.0 2.2e-216 NP_001284599 (OMIM: 605667) ral guanine nucleotide ( 766) 4710 714.8 3.4e-205 NP_001284598 (OMIM: 605667) ral guanine nucleotide ( 766) 4710 714.8 3.4e-205 XP_016856245 (OMIM: 605667) PREDICTED: ral guanine ( 683) 3845 585.8 2e-166 XP_011507643 (OMIM: 605667) PREDICTED: ral guanine ( 718) 3784 576.7 1.1e-163 XP_011507644 (OMIM: 605667) PREDICTED: ral guanine ( 620) 3767 574.2 5.7e-163 NP_001284601 (OMIM: 605667) ral guanine nucleotide ( 739) 2779 427.0 1.4e-118 NP_001035827 (OMIM: 601619) ral guanine nucleotide ( 859) 1750 273.6 2.5e-72 NP_001258703 (OMIM: 601619) ral guanine nucleotide ( 885) 1750 273.6 2.5e-72 NP_001258705 (OMIM: 601619) ral guanine nucleotide ( 902) 1750 273.6 2.6e-72 NP_001258704 (OMIM: 601619) ral guanine nucleotide ( 913) 1750 273.6 2.6e-72 NP_006257 (OMIM: 601619) ral guanine nucleotide di ( 914) 1750 273.6 2.6e-72 NP_001030300 (OMIM: 616743) ral guanine nucleotide ( 710) 598 101.9 1e-20 NP_001155088 (OMIM: 616743) ral guanine nucleotide ( 716) 598 101.9 1e-20 XP_011513087 (OMIM: 602306) PREDICTED: ral guanine ( 496) 570 97.6 1.3e-19 NP_001230667 (OMIM: 602306) ral guanine nucleotide ( 695) 570 97.7 1.8e-19 NP_004752 (OMIM: 602306) ral guanine nucleotide di ( 777) 570 97.7 2e-19 NP_705843 (OMIM: 612214) ral-GDS-related protein i ( 473) 520 90.2 2.2e-17 NP_001316353 (OMIM: 612214) ral-GDS-related protei ( 580) 520 90.2 2.6e-17 XP_011513083 (OMIM: 602306) PREDICTED: ral guanine ( 670) 403 72.8 5.4e-12 NP_722522 (OMIM: 606600) ras-specific guanine nucl ( 489) 309 58.7 6.6e-08 XP_016877948 (OMIM: 606600) PREDICTED: ras-specifi (1185) 316 59.9 7.3e-08 XP_011520169 (OMIM: 606600) PREDICTED: ras-specifi (1198) 316 59.9 7.3e-08 XP_016877947 (OMIM: 606600) PREDICTED: ras-specifi (1245) 315 59.7 8.4e-08 XP_016877946 (OMIM: 606600) PREDICTED: ras-specifi (1248) 315 59.7 8.5e-08 XP_011520168 (OMIM: 606600) PREDICTED: ras-specifi (1261) 315 59.7 8.5e-08 NP_001177659 (OMIM: 614444) ras-specific guanine n ( 305) 301 57.5 9.8e-08 XP_016870839 (OMIM: 614444) PREDICTED: ras-specifi ( 384) 301 57.5 1.2e-07 XP_011517540 (OMIM: 614444) PREDICTED: ras-specifi ( 474) 301 57.5 1.5e-07 NP_001139120 (OMIM: 606600) ras-specific guanine n (1257) 309 58.9 1.6e-07 XP_016877945 (OMIM: 606600) PREDICTED: ras-specifi (1260) 309 58.9 1.6e-07 NP_001309253 (OMIM: 614444) ras-specific guanine n ( 514) 301 57.6 1.6e-07 XP_011517538 (OMIM: 614444) PREDICTED: ras-specifi ( 515) 301 57.6 1.6e-07 XP_016877944 (OMIM: 606600) PREDICTED: ras-specifi (1270) 309 58.9 1.6e-07 NP_002882 (OMIM: 606600) ras-specific guanine nucl (1273) 309 58.9 1.6e-07 XP_016870837 (OMIM: 614444) PREDICTED: ras-specifi ( 527) 301 57.6 1.6e-07 NP_001177657 (OMIM: 614444) ras-specific guanine n ( 529) 301 57.6 1.6e-07 NP_001309249 (OMIM: 614444) ras-specific guanine n ( 537) 301 57.6 1.7e-07 NP_001177658 (OMIM: 614444) ras-specific guanine n ( 537) 301 57.6 1.7e-07 XP_016870835 (OMIM: 614444) PREDICTED: ras-specifi ( 549) 301 57.6 1.7e-07 NP_055451 (OMIM: 614444) ras-specific guanine nucl ( 557) 301 57.6 1.7e-07 XP_016870836 (OMIM: 614444) PREDICTED: ras-specifi ( 557) 301 57.6 1.7e-07 XP_016870834 (OMIM: 614444) PREDICTED: ras-specifi ( 569) 301 57.6 1.7e-07 NP_001309251 (OMIM: 614444) ras-specific guanine n ( 576) 301 57.6 1.8e-07 NP_001309250 (OMIM: 614444) ras-specific guanine n ( 584) 301 57.6 1.8e-07 XP_011517535 (OMIM: 614444) PREDICTED: ras-specifi ( 585) 301 57.6 1.8e-07 XP_011517534 (OMIM: 614444) PREDICTED: ras-specifi ( 590) 301 57.6 1.8e-07 XP_011517533 (OMIM: 614444) PREDICTED: ras-specifi ( 591) 301 57.6 1.8e-07 >>NP_001284600 (OMIM: 605667) ral guanine nucleotide dis (768 aa) initn: 5021 init1: 5021 opt: 5021 Z-score: 4055.4 bits: 761.1 E(85289): 0 Smith-Waterman score: 5021; 100.0% identity (100.0% similar) in 768 aa overlap (1-768:1-768) 10 20 30 40 50 60 pF1KSD MKLLWQAKMSSIQDWGEEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKLLWQAKMSSIQDWGEEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD YETCKIRTIKAGTLEKLVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YETCKIRTIKAGTLEKLVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TSPNCEEDGSQSSSESKMVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPNCEEDGSQSSSESKMVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GSDPERRAQNLLEQFQKQEVETDNGLPNTISFSLEEEEELEGGESAEFTCFSEDLVAEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSDPERRAQNLLEQFQKQEVETDNGLPNTISFSLEEEEELEGGESAEFTCFSEDLVAEQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TYMDAQLFKKVVPHHCLGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVSTILGGKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TYMDAQLFKKVVPHHCLGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVSTILGGKEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLMFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLMFEE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LSDIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSDIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GTFLTDLTMLDTALQDYIEGGLINFEKRRREFEVIAQIKLLQSACNSYCMTPDQKFIQWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTFLTDLTMLDTALQDYIEGGLINFEKRRREFEVIAQIKLLQSACNSYCMTPDQKFIQWF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QRQQLLTEEESYALSCEIEAAADASTTSPKPRKSMVKRLSLLFLGSDMITSPTPTKEQPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRQQLLTEEESYALSCEIEAAADASTTSPKPRKSMVKRLSLLFLGSDMITSPTPTKEQPK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD STASGSSGESMDSVSVSSCESNHSEAEEGSITPMDTPDEPQKKLSESSSSCSSIHSMDTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STASGSSGESMDSVSVSSCESNHSEAEEGSITPMDTPDEPQKKLSESSSSCSSIHSMDTN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD SSGMSSLINPLSSPPSCNNNPKIHKRSVSVTSITSTVLPPVYNQQNEDTCIIRISVEDNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGMSSLINPLSSPPSCNNNPKIHKRSVSVTSITSTVLPPVYNQQNEDTCIIRISVEDNN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GNMYKSIMLTSQDKTPAVIQRAMLKHNLDSDPAEEYELVQVISEDKELVIPDSANVFYAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNMYKSIMLTSQDKTPAVIQRAMLKHNLDSDPAEEYELVQVISEDKELVIPDSANVFYAM 670 680 690 700 710 720 730 740 750 760 pF1KSD NSQVNFDFILRKKNSMEEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSQVNFDFILRKKNSMEEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL 730 740 750 760 >>XP_011507641 (OMIM: 605667) PREDICTED: ral guanine nuc (803 aa) initn: 4959 init1: 4959 opt: 4960 Z-score: 4005.9 bits: 752.0 E(85289): 2.2e-216 Smith-Waterman score: 4960; 99.0% identity (99.5% similar) in 768 aa overlap (4-768:36-803) 10 20 30 pF1KSD MKLLWQA---KMSSIQDWGEEVEEGAVYHVTLK .:.. . ::::::::::::::::::::: XP_011 VGEPTQEVSKFKLSTKVESTGHWLVEDHVRIWEVLKTEESSIQDWGEEVEEGAVYHVTLK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD RVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDF 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD TYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSESKMVIRNAIASILRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSESKMVIRNAIASILRA 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD WLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQKQEVETDNGLPNTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQKQEVETDNGLPNTI 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD SFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHCLGCIWSRRDKKENK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHCLGCIWSRRDKKENK 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD HLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRA 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD IVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRELLMKEGTSKFANLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRELLMKEGTSKFANLD 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD SSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEGGLINFEKRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEGGLINFEKRRR 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD EFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSCEIEAAADASTTSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSCEIEAAADASTTSPK 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD PRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSVSSCESNHSEAEEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSVSSCESNHSEAEEGS 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD ITPMDTPDEPQKKLSESSSSCSSIHSMDTNSSGMSSLINPLSSPPSCNNNPKIHKRSVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITPMDTPDEPQKKLSESSSSCSSIHSMDTNSSGMSSLINPLSSPPSCNNNPKIHKRSVSV 610 620 630 640 650 660 640 650 660 670 680 690 pF1KSD TSITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMLKHNLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMLKHNLDS 670 680 690 700 710 720 700 710 720 730 740 750 pF1KSD DPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSMEEQVKLRSRTSLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSMEEQVKLRSRTSLTL 730 740 750 760 770 780 760 pF1KSD PRTAKRGCWSNRHSKITL :::::::::::::::::: XP_011 PRTAKRGCWSNRHSKITL 790 800 >>NP_055964 (OMIM: 605667) ral guanine nucleotide dissoc (803 aa) initn: 4959 init1: 4959 opt: 4960 Z-score: 4005.9 bits: 752.0 E(85289): 2.2e-216 Smith-Waterman score: 4960; 99.0% identity (99.5% similar) in 768 aa overlap (4-768:36-803) 10 20 30 pF1KSD MKLLWQA---KMSSIQDWGEEVEEGAVYHVTLK .:.. . ::::::::::::::::::::: NP_055 VGEPTQEVSKFKLSTKVESTGHWLVEDHVRIWEVLKTEESSIQDWGEEVEEGAVYHVTLK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD RVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDF 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD TYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSESKMVIRNAIASILRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSESKMVIRNAIASILRA 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD WLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQKQEVETDNGLPNTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 WLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQKQEVETDNGLPNTI 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD SFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHCLGCIWSRRDKKENK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHCLGCIWSRRDKKENK 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD HLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRA 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD IVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRELLMKEGTSKFANLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRELLMKEGTSKFANLD 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD SSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEGGLINFEKRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEGGLINFEKRRR 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD EFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSCEIEAAADASTTSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSCEIEAAADASTTSPK 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD PRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSVSSCESNHSEAEEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSVSSCESNHSEAEEGS 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD ITPMDTPDEPQKKLSESSSSCSSIHSMDTNSSGMSSLINPLSSPPSCNNNPKIHKRSVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ITPMDTPDEPQKKLSESSSSCSSIHSMDTNSSGMSSLINPLSSPPSCNNNPKIHKRSVSV 610 620 630 640 650 660 640 650 660 670 680 690 pF1KSD TSITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMLKHNLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TSITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMLKHNLDS 670 680 690 700 710 720 700 710 720 730 740 750 pF1KSD DPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSMEEQVKLRSRTSLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSMEEQVKLRSRTSLTL 730 740 750 760 770 780 760 pF1KSD PRTAKRGCWSNRHSKITL :::::::::::::::::: NP_055 PRTAKRGCWSNRHSKITL 790 800 >>NP_001284599 (OMIM: 605667) ral guanine nucleotide dis (766 aa) initn: 4710 init1: 4710 opt: 4710 Z-score: 3804.9 bits: 714.8 E(85289): 3.4e-205 Smith-Waterman score: 4710; 100.0% identity (100.0% similar) in 722 aa overlap (47-768:45-766) 20 30 40 50 60 70 pF1KSD EEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEK :::::::::::::::::::::::::::::: NP_001 KFKLSTKVESTGHWLVEDHVRIWEVLKTEEVEGDQLPPGHTVSQYETCKIRTIKAGTLEK 20 30 40 50 60 70 80 90 100 110 120 130 pF1KSD LVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSES 80 90 100 110 120 130 140 150 160 170 180 190 pF1KSD KMVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQ 140 150 160 170 180 190 200 210 220 230 240 250 pF1KSD KQEVETDNGLPNTISFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQEVETDNGLPNTISFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHC 200 210 220 230 240 250 260 270 280 290 300 310 pF1KSD LGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIA 260 270 280 290 300 310 320 330 340 350 360 370 pF1KSD HECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRE 320 330 340 350 360 370 380 390 400 410 420 430 pF1KSD LLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQD 380 390 400 410 420 430 440 450 460 470 480 490 pF1KSD YIEGGLINFEKRRREFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIEGGLINFEKRRREFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSC 440 450 460 470 480 490 500 510 520 530 540 550 pF1KSD EIEAAADASTTSPKPRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIEAAADASTTSPKPRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSV 500 510 520 530 540 550 560 570 580 590 600 610 pF1KSD SSCESNHSEAEEGSITPMDTPDEPQKKLSESSSSCSSIHSMDTNSSGMSSLINPLSSPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSCESNHSEAEEGSITPMDTPDEPQKKLSESSSSCSSIHSMDTNSSGMSSLINPLSSPPS 560 570 580 590 600 610 620 630 640 650 660 670 pF1KSD CNNNPKIHKRSVSVTSITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNNNPKIHKRSVSVTSITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTP 620 630 640 650 660 670 680 690 700 710 720 730 pF1KSD AVIQRAMLKHNLDSDPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVIQRAMLKHNLDSDPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSM 680 690 700 710 720 730 740 750 760 pF1KSD EEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL :::::::::::::::::::::::::::::::: NP_001 EEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL 740 750 760 >>NP_001284598 (OMIM: 605667) ral guanine nucleotide dis (766 aa) initn: 4710 init1: 4710 opt: 4710 Z-score: 3804.9 bits: 714.8 E(85289): 3.4e-205 Smith-Waterman score: 4710; 100.0% identity (100.0% similar) in 722 aa overlap (47-768:45-766) 20 30 40 50 60 70 pF1KSD EEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEK :::::::::::::::::::::::::::::: NP_001 KFKLSTKVESTGHWLVEDHVRIWEVLKTEEVEGDQLPPGHTVSQYETCKIRTIKAGTLEK 20 30 40 50 60 70 80 90 100 110 120 130 pF1KSD LVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSES 80 90 100 110 120 130 140 150 160 170 180 190 pF1KSD KMVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQ 140 150 160 170 180 190 200 210 220 230 240 250 pF1KSD KQEVETDNGLPNTISFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQEVETDNGLPNTISFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHC 200 210 220 230 240 250 260 270 280 290 300 310 pF1KSD LGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIA 260 270 280 290 300 310 320 330 340 350 360 370 pF1KSD HECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRE 320 330 340 350 360 370 380 390 400 410 420 430 pF1KSD LLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQD 380 390 400 410 420 430 440 450 460 470 480 490 pF1KSD YIEGGLINFEKRRREFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIEGGLINFEKRRREFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSC 440 450 460 470 480 490 500 510 520 530 540 550 pF1KSD EIEAAADASTTSPKPRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIEAAADASTTSPKPRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSV 500 510 520 530 540 550 560 570 580 590 600 610 pF1KSD SSCESNHSEAEEGSITPMDTPDEPQKKLSESSSSCSSIHSMDTNSSGMSSLINPLSSPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSCESNHSEAEEGSITPMDTPDEPQKKLSESSSSCSSIHSMDTNSSGMSSLINPLSSPPS 560 570 580 590 600 610 620 630 640 650 660 670 pF1KSD CNNNPKIHKRSVSVTSITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNNNPKIHKRSVSVTSITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTP 620 630 640 650 660 670 680 690 700 710 720 730 pF1KSD AVIQRAMLKHNLDSDPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVIQRAMLKHNLDSDPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSM 680 690 700 710 720 730 740 750 760 pF1KSD EEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL :::::::::::::::::::::::::::::::: NP_001 EEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL 740 750 760 >>XP_016856245 (OMIM: 605667) PREDICTED: ral guanine nuc (683 aa) initn: 3836 init1: 3836 opt: 3845 Z-score: 3108.9 bits: 585.8 E(85289): 2e-166 Smith-Waterman score: 4289; 88.9% identity (88.9% similar) in 768 aa overlap (1-768:1-683) 10 20 30 40 50 60 pF1KSD MKLLWQAKMSSIQDWGEEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKLLWQAKMSSIQDWGEEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD YETCKIRTIKAGTLEKLVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YETCKIRTIKAGTLEKLVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TSPNCEEDGSQSSSESKMVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSPNCEEDGSQSSSESKMVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GSDPERRAQNLLEQFQKQEVETDNGLPNTISFSLEEEEELEGGESAEFTCFSEDLVAEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSDPERRAQNLLEQFQKQEVETDNGLPNTISFSLEEEEELEGGESAEFTCFSEDLVAEQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TYMDAQLFKKVVPHHCLGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVSTILGGKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYMDAQLFKKVVPHHCLGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVSTILGGKEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLMFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLMFEE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LSDIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSDIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GTFLTDLTMLDTALQDYIEGGLINFEKRRREFEVIAQIKLLQSACNSYCMTPDQKFIQWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTFLTDLTMLDTALQDYIEGGLINFEKRRREFEVIAQIKLLQSACNSYCMTPDQKFIQWF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD QRQQLLTEEESYALSCEIEAAADASTTSPKPRKSMVKRLSLLFLGSDMITSPTPTKEQPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRQQLLTEEESYALSCEIEAAADASTTSPKPRKSMVKRLSLLFLGSDMITSPTPTKEQPK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD STASGSSGESMDSVSVSSCESNHSEAEEGSITPMDTPDEPQKKLSESSSSCSSIHSMDTN :::::::::::::::::::::::::::::::::::::::::::: XP_016 STASGSSGESMDSVSVSSCESNHSEAEEGSITPMDTPDEPQKKL---------------- 550 560 570 580 610 620 630 640 650 660 pF1KSD SSGMSSLINPLSSPPSCNNNPKIHKRSVSVTSITSTVLPPVYNQQNEDTCIIRISVEDNN XP_016 ------------------------------------------------------------ 670 680 690 700 710 720 pF1KSD GNMYKSIMLTSQDKTPAVIQRAMLKHNLDSDPAEEYELVQVISEDKELVIPDSANVFYAM ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ---------TSQDKTPAVIQRAMLKHNLDSDPAEEYELVQVISEDKELVIPDSANVFYAM 590 600 610 620 630 730 740 750 760 pF1KSD NSQVNFDFILRKKNSMEEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSQVNFDFILRKKNSMEEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL 640 650 660 670 680 >>XP_011507643 (OMIM: 605667) PREDICTED: ral guanine nuc (718 aa) initn: 3773 init1: 3773 opt: 3784 Z-score: 3059.4 bits: 576.7 E(85289): 1.1e-163 Smith-Waterman score: 4228; 87.9% identity (88.4% similar) in 768 aa overlap (4-768:36-718) 10 20 30 pF1KSD MKLLWQA---KMSSIQDWGEEVEEGAVYHVTLK .:.. . ::::::::::::::::::::: XP_011 VGEPTQEVSKFKLSTKVESTGHWLVEDHVRIWEVLKTEESSIQDWGEEVEEGAVYHVTLK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD RVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDF 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD TYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSESKMVIRNAIASILRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSESKMVIRNAIASILRA 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD WLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQKQEVETDNGLPNTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQKQEVETDNGLPNTI 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD SFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHCLGCIWSRRDKKENK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHCLGCIWSRRDKKENK 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD HLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRA 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD IVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRELLMKEGTSKFANLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRELLMKEGTSKFANLD 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD SSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEGGLINFEKRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEGGLINFEKRRR 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD EFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSCEIEAAADASTTSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSCEIEAAADASTTSPK 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD PRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSVSSCESNHSEAEEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSVSSCESNHSEAEEGS 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD ITPMDTPDEPQKKLSESSSSCSSIHSMDTNSSGMSSLINPLSSPPSCNNNPKIHKRSVSV :::::::::::::: XP_011 ITPMDTPDEPQKKL---------------------------------------------- 610 640 650 660 670 680 690 pF1KSD TSITSTVLPPVYNQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMLKHNLDS ::::::::::::::::::::: XP_011 ---------------------------------------TSQDKTPAVIQRAMLKHNLDS 620 630 640 700 710 720 730 740 750 pF1KSD DPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSMEEQVKLRSRTSLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPAEEYELVQVISEDKELVIPDSANVFYAMNSQVNFDFILRKKNSMEEQVKLRSRTSLTL 650 660 670 680 690 700 760 pF1KSD PRTAKRGCWSNRHSKITL :::::::::::::::::: XP_011 PRTAKRGCWSNRHSKITL 710 >>XP_011507644 (OMIM: 605667) PREDICTED: ral guanine nuc (620 aa) initn: 3766 init1: 3766 opt: 3767 Z-score: 3046.8 bits: 574.2 E(85289): 5.7e-163 Smith-Waterman score: 3767; 98.6% identity (99.3% similar) in 583 aa overlap (4-583:36-618) 10 20 30 pF1KSD MKLLWQA---KMSSIQDWGEEVEEGAVYHVTLK .:.. . ::::::::::::::::::::: XP_011 VGEPTQEVSKFKLSTKVESTGHWLVEDHVRIWEVLKTEESSIQDWGEEVEEGAVYHVTLK 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD RVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVQIQQAANKGARWLGVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDF 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD TYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSESKMVIRNAIASILRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYISIFLSTYRGFASTKEVLELLLDRYGNLTSPNCEEDGSQSSSESKMVIRNAIASILRA 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD WLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQKQEVETDNGLPNTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WLDQCAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQKQEVETDNGLPNTI 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD SFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHCLGCIWSRRDKKENK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFSLEEEEELEGGESAEFTCFSEDLVAEQLTYMDAQLFKKVVPHHCLGCIWSRRDKKENK 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD HLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLAPTIRATISQFNTLTKCVVSTILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRA 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD IVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRELLMKEGTSKFANLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVSALQSNSIYRLKKTWAAVPRDRMLMFEELSDIFSDHNNHLTSRELLMKEGTSKFANLD 370 380 390 400 410 420 400 410 420 430 440 450 pF1KSD SSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEGGLINFEKRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSVKENQKRTQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEGGLINFEKRRR 430 440 450 460 470 480 460 470 480 490 500 510 pF1KSD EFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSCEIEAAADASTTSPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFEVIAQIKLLQSACNSYCMTPDQKFIQWFQRQQLLTEEESYALSCEIEAAADASTTSPK 490 500 510 520 530 540 520 530 540 550 560 570 pF1KSD PRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSVSSCESNHSEAEEGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRKSMVKRLSLLFLGSDMITSPTPTKEQPKSTASGSSGESMDSVSVSSCESNHSEAEEGS 550 560 570 580 590 600 580 590 600 610 620 630 pF1KSD ITPMDTPDEPQKKLSESSSSCSSIHSMDTNSSGMSSLINPLSSPPSCNNNPKIHKRSVSV ::::::::::::: XP_011 ITPMDTPDEPQKKAL 610 620 >>NP_001284601 (OMIM: 605667) ral guanine nucleotide dis (739 aa) initn: 2740 init1: 2710 opt: 2779 Z-score: 2249.6 bits: 427.0 E(85289): 1.4e-118 Smith-Waterman score: 4767; 96.2% identity (96.2% similar) in 768 aa overlap (1-768:1-739) 10 20 30 40 50 60 pF1KSD MKLLWQAKMSSIQDWGEEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKLLWQAKMSSIQDWGEEVEEGAVYHVTLKRVQIQQAANKGARWLGVEGDQLPPGHTVSQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD YETCKIRTIKAGTLEKLVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YETCKIRTIKAGTLEKLVENLLTAFGDNDFTYISIFLSTYRGFASTKEVLELLLDRYGNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TSPNCEEDGSQSSSESKMVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPNCEEDGSQSSSESKMVIRNAIASILRAWLDQCAEDFREPPHFPCLQKLLDYLTRMMP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GSDPERRAQNLLEQFQKQEVETDNGLPNTISFSLEEEEELEGGESAEFTCFSEDLVAEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSDPERRAQNLLEQFQKQEVETDNGLPNTISFSLEEEEELEGGESAEFTCFSEDLVAEQL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TYMDAQLFKKVVPHHCLGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVSTILGGKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TYMDAQLFKKVVPHHCLGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVSTILGGKEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLMFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRDRMLMFEE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LSDIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVMQGTVPYL ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSDIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMG--------- 370 380 390 400 410 430 440 450 460 470 480 pF1KSD GTFLTDLTMLDTALQDYIEGGLINFEKRRREFEVIAQIKLLQSACNSYCMTPDQKFIQWF :::::::::::::::::::::::::::::::::::::::: NP_001 --------------------GLINFEKRRREFEVIAQIKLLQSACNSYCMTPDQKFIQWF 420 430 440 450 490 500 510 520 530 540 pF1KSD QRQQLLTEEESYALSCEIEAAADASTTSPKPRKSMVKRLSLLFLGSDMITSPTPTKEQPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRQQLLTEEESYALSCEIEAAADASTTSPKPRKSMVKRLSLLFLGSDMITSPTPTKEQPK 460 470 480 490 500 510 550 560 570 580 590 600 pF1KSD STASGSSGESMDSVSVSSCESNHSEAEEGSITPMDTPDEPQKKLSESSSSCSSIHSMDTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STASGSSGESMDSVSVSSCESNHSEAEEGSITPMDTPDEPQKKLSESSSSCSSIHSMDTN 520 530 540 550 560 570 610 620 630 640 650 660 pF1KSD SSGMSSLINPLSSPPSCNNNPKIHKRSVSVTSITSTVLPPVYNQQNEDTCIIRISVEDNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGMSSLINPLSSPPSCNNNPKIHKRSVSVTSITSTVLPPVYNQQNEDTCIIRISVEDNN 580 590 600 610 620 630 670 680 690 700 710 720 pF1KSD GNMYKSIMLTSQDKTPAVIQRAMLKHNLDSDPAEEYELVQVISEDKELVIPDSANVFYAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNMYKSIMLTSQDKTPAVIQRAMLKHNLDSDPAEEYELVQVISEDKELVIPDSANVFYAM 640 650 660 670 680 690 730 740 750 760 pF1KSD NSQVNFDFILRKKNSMEEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSQVNFDFILRKKNSMEEQVKLRSRTSLTLPRTAKRGCWSNRHSKITL 700 710 720 730 >>NP_001035827 (OMIM: 601619) ral guanine nucleotide dis (859 aa) initn: 1881 init1: 751 opt: 1750 Z-score: 1419.6 bits: 273.6 E(85289): 2.5e-72 Smith-Waterman score: 1934; 44.7% identity (66.8% similar) in 805 aa overlap (76-757:68-851) 50 60 70 80 90 100 pF1KSD GVEGDQLPPGHTVSQYETCKIRTIKAGTLEKLVENLLTAFGDNDFTYISIFLSTYRGFAS ::::.:. :: .:..:..::: :::.:.. NP_001 GQRWLGYENESALNLYETCKVRTVKAGTLEKLVEHLVPAFQGSDLSYVTIFLCTYRAFTT 40 50 60 70 80 90 110 120 130 140 150 pF1KSD TKEVLELLLDRYGN---LTS--------PNCEEDGSQSSSESKMVIRNAIASILRAWLDQ :..::.::. ::: ::. : .:::. ... ..:::.::: .:::: NP_001 TQQVLDLLFKRYGRCDALTASSRYGCILPYSDEDGGPQDQ-----LKNAISSILGTWLDQ 100 110 120 130 140 150 160 170 180 190 200 pF1KSD CAEDFREPPHFPCLQKLLDYLTRMMPGSDPERRAQNLLEQFQKQE-VETDN--------- .::: .:: ::::..:. :. ::::: ::::. :: :....: .:.. NP_001 YSEDFCQPPDFPCLKQLVAYVQLNMPGSDLERRAHLLLAQLEHSEPIEAEPEALSPVPAL 160 170 180 190 200 210 pF1KSD --------------------------------------------------------GLPN :: . NP_001 KPTPELELALTPARAPSPVPAPAPEPEPAPTPAPGSELEVAPAPAPELQQAPEPAVGLES 220 230 240 250 260 270 210 220 230 pF1KSD TISFSLEEEE------------ELE--------------------GGESAE---FTCFSE . . .:: : ::: .: : : . : NP_001 APAPALELEPAPEQDPAPSQTLELEPAPAPVPSLQPSWPSPVVAENGLSEEKPHLLVFPP 280 290 300 310 320 330 240 250 260 270 280 290 pF1KSD DLVAEQLTYMDAQLFKKVVPHHCLGCIWSRRDKKENKHLAPTIRATISQFNTLTKCVVST ::::::.: :::.:::::::.:::: :::.:::: ..:::::::::..:::....::..: NP_001 DLVAEQFTLMDAELFKKVVPYHCLGSIWSQRDKKGKEHLAPTIRATVTQFNSVANCVITT 340 350 360 370 380 390 300 310 320 330 340 350 pF1KSD ILGGKELKTQQRAKIIEKWINIAHECRLLKNFSSLRAIVSALQSNSIYRLKKTWAAVPRD ::.. :. .::...:.::..:.:::.::::::: ::.::::::::.:::::: : :: NP_001 CLGNRSTKAPDRARVVEHWIEVARECRILKNFSSLYAILSALQSNSIHRLKKTWEDVSRD 400 410 420 430 440 450 360 370 380 390 400 410 pF1KSD RMLMFEELSDIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKRTQRRLQLQKDMGVM . .:..::.::::.::. :::::.::::::::.:. : ::.:.: :. :.. NP_001 SFRIFQKLSEIFSDENNYSLSRELLIKEGTSKFATLE----MNPKRAQKR---PKETGII 460 470 480 490 500 420 430 440 450 460 470 pF1KSD QGTVPYLGTFLTDLTMLDTALQDYIEGGLINFEKRRREFEVIAQIKLLQSACNSYCMTPD ::::::::::::::.:::::..::. : ::::::::.::::::::::::::::.: ..:: NP_001 QGTVPYLGTFLTDLVMLDTAMKDYLYGRLINFEKRRKEFEVIAQIKLLQSACNNYSIAPD 510 520 530 540 550 560 480 490 500 510 520 530 pF1KSD QKFIQWFQRQQLLTEEESYALSCEIEAAADASTTSPKPRKS--MVKRLSLLFLGSDMIT- ..: ::. . :.: ::: ::::.: ....... . .:. .::: : : .. NP_001 EQFGAWFRAVERLSETESYNLSCELEPPSESASNTLRTKKNTAIVKRWSDRQAPSTELST 570 580 590 600 610 620 540 550 560 570 580 pF1KSD ---SPTPTKEQPKSTASGSSGESMDSVSVSSCESNHSEAEEGSITPM-DTPDEPQKKLSE : . . .: . :::. :..:: : :. :..:: .:. . ..:: .::. : NP_001 SGSSHSKSCDQLRCGPYLSSGDIADALSVHSAGSSSSDVEEINISFVPESPDGQEKKFWE 630 640 650 660 670 680 590 600 610 620 630 640 pF1KSD SSSSCSSIHSMDTNSSGMSSLINPLSSPPSCNNNP----KIHKRSVSVTSITSTVLPPVY :.:. : ..::.:: . :: : ...: . :::::: .:..:: .: NP_001 SASQSSP------ETSGISSASSSTSSS-SASTTPVAATRTHKRSVSGLCNSSSALP-LY 690 700 710 720 730 650 660 670 680 690 700 pF1KSD NQQNEDTCIIRISVEDNNGNMYKSIMLTSQDKTPAVIQRAMLKHNLDSDPAEEYELVQVI ::: : ::::.:.. .::::::::..:::::.::::..:: ::::. . :.:::.:.. NP_001 NQQVGDCCIIRVSLDVDNGNMYKSILVTSQDKAPAVIRKAMDKHNLEEEEPEDYELLQIL 740 750 760 770 780 790 710 720 730 740 750 760 pF1KSD SEDKELVIPDSANVFYAMNSQVNFDFILRKKNSMEEQVKLRSRTSLTLPRTAKRGCWSNR :.:..: ::..::::::::: .:.::.:.:. .. . ::.. .: :::: ..: NP_001 SDDRKLKIPENANVFYAMNSTANYDFVLKKR-TFTKGVKVKHGASSTLPRMKQKGLKIAK 800 810 820 830 840 850 pF1KSD HSKITL NP_001 GIF 768 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:52:49 2016 done: Thu Nov 3 18:52:51 2016 Total Scan time: 10.090 Total Display time: 0.220 Function used was FASTA [36.3.4 Apr, 2011]