FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0965, 464 aa 1>>>pF1KSDA0965 464 - 464 aa - 464 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.3367+/-0.000611; mu= -27.3706+/- 0.037 mean_var=905.4502+/-203.021, 0's: 0 Z-trim(113.6): 684 B-trim: 0 in 0/59 Lambda= 0.042623 statistics sampled from 22398 (23082) to 22398 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.271), width: 16 Scan time: 8.370 The best scores are: opt bits E(85289) XP_006719121 (OMIM: 615836) PREDICTED: serine/thre ( 464) 3101 207.4 6.8e-53 NP_055815 (OMIM: 615836) serine/threonine-protein ( 464) 3101 207.4 6.8e-53 XP_016874525 (OMIM: 615836) PREDICTED: serine/thre ( 464) 3101 207.4 6.8e-53 XP_006719122 (OMIM: 615836) PREDICTED: serine/thre ( 412) 2781 187.6 5.3e-47 XP_006715052 (OMIM: 606964) PREDICTED: serine/thre ( 465) 2707 183.2 1.3e-45 NP_001292031 (OMIM: 606964) serine/threonine-prote ( 465) 2707 183.2 1.3e-45 XP_006715051 (OMIM: 606964) PREDICTED: serine/thre ( 465) 2707 183.2 1.3e-45 NP_009202 (OMIM: 606964) serine/threonine-protein ( 465) 2707 183.2 1.3e-45 XP_016865715 (OMIM: 606964) PREDICTED: serine/thre ( 439) 2511 171.1 5.5e-42 XP_011518915 (OMIM: 615836) PREDICTED: serine/thre ( 371) 2462 168.0 4e-41 XP_005253399 (OMIM: 615836) PREDICTED: serine/thre ( 423) 2462 168.0 4.3e-41 XP_016866970 (OMIM: 603473) PREDICTED: serine/thre ( 850) 792 65.7 5.4e-10 XP_016866969 (OMIM: 603473) PREDICTED: serine/thre ( 883) 792 65.8 5.6e-10 XP_016866968 (OMIM: 603473) PREDICTED: serine/thre ( 993) 792 65.8 6e-10 XP_011534554 (OMIM: 603473) PREDICTED: serine/thre (1001) 792 65.8 6e-10 XP_016866967 (OMIM: 603473) PREDICTED: serine/thre (1025) 792 65.9 6.1e-10 XP_016866966 (OMIM: 603473) PREDICTED: serine/thre (1034) 792 65.9 6.1e-10 XP_016866965 (OMIM: 603473) PREDICTED: serine/thre (1058) 792 65.9 6.2e-10 NP_004681 (OMIM: 603473) serine/threonine-protein (1130) 792 65.9 6.5e-10 XP_016866963 (OMIM: 603473) PREDICTED: serine/thre (1163) 792 65.9 6.6e-10 XP_016866964 (OMIM: 603473) PREDICTED: serine/thre (1163) 792 65.9 6.6e-10 XP_006715666 (OMIM: 603473) PREDICTED: serine/thre ( 886) 787 65.5 6.9e-10 XP_016876031 (OMIM: 604861) PREDICTED: serine/thre ( 906) 787 65.5 7e-10 XP_016876030 (OMIM: 604861) PREDICTED: serine/thre ( 981) 787 65.5 7.3e-10 XP_011533344 (OMIM: 604861) PREDICTED: serine/thre (1001) 787 65.5 7.4e-10 NP_055387 (OMIM: 604861) serine/threonine-protein (1088) 787 65.6 7.8e-10 XP_005266399 (OMIM: 604861) PREDICTED: serine/thre (1088) 787 65.6 7.8e-10 XP_016873487 (OMIM: 613991) PREDICTED: serine/thre (1081) 629 55.9 6.6e-07 XP_011543463 (OMIM: 613991) PREDICTED: serine/thre (1135) 629 55.9 6.8e-07 XP_016873486 (OMIM: 613991) PREDICTED: serine/thre (1139) 629 55.9 6.8e-07 NP_001275693 (OMIM: 160900,605377) myotonin-protei ( 655) 620 55.0 7.1e-07 XP_011543461 (OMIM: 613991) PREDICTED: serine/thre (1481) 629 56.0 7.9e-07 XP_011543460 (OMIM: 613991) PREDICTED: serine/thre (1495) 629 56.0 8e-07 XP_011543459 (OMIM: 613991) PREDICTED: serine/thre (1530) 629 56.1 8.1e-07 NP_059995 (OMIM: 613991) serine/threonine-protein (1551) 629 56.1 8.2e-07 XP_011543458 (OMIM: 613991) PREDICTED: serine/thre (1562) 629 56.1 8.2e-07 XP_016873485 (OMIM: 613991) PREDICTED: serine/thre (1568) 629 56.1 8.2e-07 XP_011543457 (OMIM: 613991) PREDICTED: serine/thre (1569) 629 56.1 8.2e-07 NP_001275695 (OMIM: 160900,605377) myotonin-protei ( 530) 612 54.4 8.8e-07 NP_001075029 (OMIM: 160900,605377) myotonin-protei ( 624) 612 54.5 9.7e-07 NP_001075031 (OMIM: 160900,605377) myotonin-protei ( 625) 612 54.5 9.7e-07 NP_004400 (OMIM: 160900,605377) myotonin-protein k ( 629) 612 54.5 9.7e-07 NP_001075032 (OMIM: 160900,605377) myotonin-protei ( 639) 612 54.5 9.8e-07 NP_005397 (OMIM: 601702) rho-associated protein ki (1354) 606 54.6 2e-06 XP_011535689 (OMIM: 614062) PREDICTED: serine/thre (1460) 602 54.4 2.5e-06 XP_016858071 (OMIM: 603412) PREDICTED: serine/thre (1589) 603 54.5 2.5e-06 XP_005268287 (OMIM: 614062) PREDICTED: serine/thre (1490) 602 54.4 2.5e-06 NP_055641 (OMIM: 603412) serine/threonine-protein (1638) 603 54.5 2.6e-06 NP_003598 (OMIM: 603412) serine/threonine-protein (1719) 603 54.5 2.6e-06 XP_005273381 (OMIM: 603412) PREDICTED: serine/thre (1732) 603 54.5 2.6e-06 >>XP_006719121 (OMIM: 615836) PREDICTED: serine/threonin (464 aa) initn: 3101 init1: 3101 opt: 3101 Z-score: 1070.6 bits: 207.4 E(85289): 6.8e-53 Smith-Waterman score: 3101; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464) 10 20 30 40 50 60 pF1KSD MAMTAGTTTTFPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAMTAGTTTTFPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLAD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD AHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDIL 370 380 390 400 410 420 430 440 450 460 pF1KSD QPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL :::::::::::::::::::::::::::::::::::::::::::: XP_006 QPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL 430 440 450 460 >>NP_055815 (OMIM: 615836) serine/threonine-protein kina (464 aa) initn: 3101 init1: 3101 opt: 3101 Z-score: 1070.6 bits: 207.4 E(85289): 6.8e-53 Smith-Waterman score: 3101; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464) 10 20 30 40 50 60 pF1KSD MAMTAGTTTTFPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAMTAGTTTTFPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLAD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD AHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDIL 370 380 390 400 410 420 430 440 450 460 pF1KSD QPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL :::::::::::::::::::::::::::::::::::::::::::: NP_055 QPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL 430 440 450 460 >>XP_016874525 (OMIM: 615836) PREDICTED: serine/threonin (464 aa) initn: 3101 init1: 3101 opt: 3101 Z-score: 1070.6 bits: 207.4 E(85289): 6.8e-53 Smith-Waterman score: 3101; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464) 10 20 30 40 50 60 pF1KSD MAMTAGTTTTFPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAMTAGTTTTFPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLAD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD AHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD FCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDIL 370 380 390 400 410 420 430 440 450 460 pF1KSD QPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL :::::::::::::::::::::::::::::::::::::::::::: XP_016 QPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL 430 440 450 460 >>XP_006719122 (OMIM: 615836) PREDICTED: serine/threonin (412 aa) initn: 2781 init1: 2781 opt: 2781 Z-score: 964.8 bits: 187.6 E(85289): 5.3e-47 Smith-Waterman score: 2781; 100.0% identity (100.0% similar) in 412 aa overlap (53-464:1-412) 30 40 50 60 70 80 pF1KSD VAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARKETEFLRLKR :::::::::::::::::::::::::::::: XP_006 MEEEGLADEEKKLRRSQHARKETEFLRLKR 10 20 30 90 100 110 120 130 140 pF1KSD TRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVAHIRAERDIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVAHIRAERDIL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KSD VEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAID 100 110 120 130 140 150 210 220 230 240 250 260 pF1KSD AIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQN 160 170 180 190 200 210 270 280 290 300 310 320 pF1KSD MNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPP 220 230 240 250 260 270 330 340 350 360 370 380 pF1KSD FCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNSGVEEIKGHPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNSGVEEIKGHPF 280 290 300 310 320 330 390 400 410 420 430 440 pF1KSD FEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDILQPVPNTTEPDYKSKDWVFLNYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDILQPVPNTTEPDYKSKDWVFLNYT 340 350 360 370 380 390 450 460 pF1KSD YKRFEGLTQRGSIPTYMKAGKL :::::::::::::::::::::: XP_006 YKRFEGLTQRGSIPTYMKAGKL 400 410 >>XP_006715052 (OMIM: 606964) PREDICTED: serine/threonin (465 aa) initn: 2683 init1: 2493 opt: 2707 Z-score: 939.6 bits: 183.2 E(85289): 1.3e-45 Smith-Waterman score: 2707; 86.9% identity (94.4% similar) in 466 aa overlap (1-463:1-465) 10 20 30 40 50 60 pF1KSD MAMTAGTTTTFPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLAD :::: :.: :::::.::::..:.:::::::::: :::::: :::::: .:::::: : XP_006 MAMT-GSTPCSSMSNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKD 10 20 30 40 50 70 80 90 100 110 120 pF1KSD EEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKI :::.:::: ::::::::::::::::::.::::::::::::::::::::::::::.::::: XP_006 EEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD LRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLM :::.::::::::.:::::::::::::. :::::::::::: ::::::::::::::::::: XP_006 LRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLM 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD KKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKK ::::::::::::::.:::::::.:::::::::::::::::::.::::::::::::::::: XP_006 KKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD AHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGY ::::::::::.:. ::::.::::::::::::::.::::::.::::::::::::::::::: XP_006 AHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGY 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILR ::::::::::::::::::::::::::::::::.:::::::::.::::::::::::::::: XP_006 NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD FCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDIL :: . :.::: ::::::.. ::::::::::::::::: :::::::::::::.::::::: XP_006 FCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESDIL 360 370 380 390 400 410 430 440 450 460 pF1KSD QPVPNTT---EPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL .:. :. : :::.:::::.::::::::::: ::.::.::::.: XP_006 KPTVATSNHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK 420 430 440 450 460 >>NP_001292031 (OMIM: 606964) serine/threonine-protein k (465 aa) initn: 2683 init1: 2493 opt: 2707 Z-score: 939.6 bits: 183.2 E(85289): 1.3e-45 Smith-Waterman score: 2707; 86.9% identity (94.4% similar) in 466 aa overlap (1-463:1-465) 10 20 30 40 50 60 pF1KSD MAMTAGTTTTFPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLAD :::: :.: :::::.::::..:.:::::::::: :::::: :::::: .:::::: : NP_001 MAMT-GSTPCSSMSNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKD 10 20 30 40 50 70 80 90 100 110 120 pF1KSD EEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKI :::.:::: ::::::::::::::::::.::::::::::::::::::::::::::.::::: NP_001 EEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD LRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLM :::.::::::::.:::::::::::::. :::::::::::: ::::::::::::::::::: NP_001 LRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLM 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD KKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKK ::::::::::::::.:::::::.:::::::::::::::::::.::::::::::::::::: NP_001 KKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD AHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGY ::::::::::.:. ::::.::::::::::::::.::::::.::::::::::::::::::: NP_001 AHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGY 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILR ::::::::::::::::::::::::::::::::.:::::::::.::::::::::::::::: NP_001 NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD FCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDIL :: . :.::: ::::::.. ::::::::::::::::: :::::::::::::.::::::: NP_001 FCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESDIL 360 370 380 390 400 410 430 440 450 460 pF1KSD QPVPNTT---EPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL .:. :. : :::.:::::.::::::::::: ::.::.::::.: NP_001 KPTVATSNHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK 420 430 440 450 460 >>XP_006715051 (OMIM: 606964) PREDICTED: serine/threonin (465 aa) initn: 2683 init1: 2493 opt: 2707 Z-score: 939.6 bits: 183.2 E(85289): 1.3e-45 Smith-Waterman score: 2707; 86.9% identity (94.4% similar) in 466 aa overlap (1-463:1-465) 10 20 30 40 50 60 pF1KSD MAMTAGTTTTFPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLAD :::: :.: :::::.::::..:.:::::::::: :::::: :::::: .:::::: : XP_006 MAMT-GSTPCSSMSNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKD 10 20 30 40 50 70 80 90 100 110 120 pF1KSD EEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKI :::.:::: ::::::::::::::::::.::::::::::::::::::::::::::.::::: XP_006 EEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD LRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLM :::.::::::::.:::::::::::::. :::::::::::: ::::::::::::::::::: XP_006 LRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLM 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD KKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKK ::::::::::::::.:::::::.:::::::::::::::::::.::::::::::::::::: XP_006 KKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD AHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGY ::::::::::.:. ::::.::::::::::::::.::::::.::::::::::::::::::: XP_006 AHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGY 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILR ::::::::::::::::::::::::::::::::.:::::::::.::::::::::::::::: XP_006 NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD FCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDIL :: . :.::: ::::::.. ::::::::::::::::: :::::::::::::.::::::: XP_006 FCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESDIL 360 370 380 390 400 410 430 440 450 460 pF1KSD QPVPNTT---EPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL .:. :. : :::.:::::.::::::::::: ::.::.::::.: XP_006 KPTVATSNHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK 420 430 440 450 460 >>NP_009202 (OMIM: 606964) serine/threonine-protein kina (465 aa) initn: 2683 init1: 2493 opt: 2707 Z-score: 939.6 bits: 183.2 E(85289): 1.3e-45 Smith-Waterman score: 2707; 86.9% identity (94.4% similar) in 466 aa overlap (1-463:1-465) 10 20 30 40 50 60 pF1KSD MAMTAGTTTTFPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLAD :::: :.: :::::.::::..:.:::::::::: :::::: :::::: .:::::: : NP_009 MAMT-GSTPCSSMSNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKD 10 20 30 40 50 70 80 90 100 110 120 pF1KSD EEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKI :::.:::: ::::::::::::::::::.::::::::::::::::::::::::::.::::: NP_009 EEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD LRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLM :::.::::::::.:::::::::::::. :::::::::::: ::::::::::::::::::: NP_009 LRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLM 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD KKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKK ::::::::::::::.:::::::.:::::::::::::::::::.::::::::::::::::: NP_009 KKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD AHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGY ::::::::::.:. ::::.::::::::::::::.::::::.::::::::::::::::::: NP_009 AHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGY 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILR ::::::::::::::::::::::::::::::::.:::::::::.::::::::::::::::: NP_009 NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD FCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDIL :: . :.::: ::::::.. ::::::::::::::::: :::::::::::::.::::::: NP_009 FCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESDIL 360 370 380 390 400 410 430 440 450 460 pF1KSD QPVPNTT---EPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL .:. :. : :::.:::::.::::::::::: ::.::.::::.: NP_009 KPTVATSNHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK 420 430 440 450 460 >>XP_016865715 (OMIM: 606964) PREDICTED: serine/threonin (439 aa) initn: 2490 init1: 2490 opt: 2511 Z-score: 874.8 bits: 171.1 E(85289): 5.5e-42 Smith-Waterman score: 2511; 88.9% identity (95.5% similar) in 422 aa overlap (1-422:1-421) 10 20 30 40 50 60 pF1KSD MAMTAGTTTTFPMSNHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLAD :::: :.: :::::.::::..:.:::::::::: :::::: :::::: .:::::: : XP_016 MAMT-GSTPCSSMSNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKD 10 20 30 40 50 70 80 90 100 110 120 pF1KSD EEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKI :::.:::: ::::::::::::::::::.::::::::::::::::::::::::::.::::: XP_016 EEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KSD LRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLM :::.::::::::.:::::::::::::. :::::::::::: ::::::::::::::::::: XP_016 LRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLM 120 130 140 150 160 170 190 200 210 220 230 240 pF1KSD KKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKK ::::::::::::::.:::::::.:::::::::::::::::::.::::::::::::::::: XP_016 KKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KSD AHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGY ::::::::::.:. ::::.::::::::::::::.::::::.::::::::::::::::::: XP_016 AHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGY 240 250 260 270 280 290 310 320 330 340 350 360 pF1KSD NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILR ::::::::::::::::::::::::::::::::.:::::::::.::::::::::::::::: XP_016 NKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILR 300 310 320 330 340 350 370 380 390 400 410 420 pF1KSD FCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDIL :: . :.::: ::::::.. ::::::::::::::::: :::::::::::::.::::::: XP_016 FCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESDIL 360 370 380 390 400 410 430 440 450 460 pF1KSD QPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL .: XP_016 KPTDAFLGDTPPHPKGSPAT 420 430 >>XP_011518915 (OMIM: 615836) PREDICTED: serine/threonin (371 aa) initn: 2462 init1: 2462 opt: 2462 Z-score: 859.3 bits: 168.0 E(85289): 4e-41 Smith-Waterman score: 2462; 100.0% identity (100.0% similar) in 362 aa overlap (103-464:10-371) 80 90 100 110 120 130 pF1KSD KETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQV :::::::::::::::::::::::::::::: XP_011 MEEEGLADEEVRLVQKKDTGHIYAMKILRKSDMLEKEQV 10 20 30 140 150 160 170 180 190 pF1KSD AHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQF 40 50 60 70 80 90 200 210 220 230 240 250 pF1KSD YISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTH 100 110 120 130 140 150 260 270 280 290 300 310 pF1KSD NPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVI 160 170 180 190 200 210 320 330 340 350 360 370 pF1KSD MYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYEMLIGYPPFCSETPQETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNS 220 230 240 250 260 270 380 390 400 410 420 430 pF1KSD GVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDILQPVPNTTEPDYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVEEIKGHPFFEGVDWEHIRERPAAIPIEIKSIDDTSNFDDFPESDILQPVPNTTEPDYK 280 290 300 310 320 330 440 450 460 pF1KSD SKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL :::::::::::::::::::::::::::::::: XP_011 SKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL 340 350 360 370 464 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:28:07 2016 done: Thu Nov 3 04:28:08 2016 Total Scan time: 8.370 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]