FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0975, 1504 aa 1>>>pF1KSDA0975 1504 - 1504 aa - 1504 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.5182+/-0.00122; mu= -3.3658+/- 0.074 mean_var=365.3297+/-74.290, 0's: 0 Z-trim(112.1): 32 B-trim: 0 in 0/54 Lambda= 0.067101 statistics sampled from 12867 (12887) to 12867 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.396), width: 16 Scan time: 6.460 The best scores are: opt bits E(32554) CCDS33767.1 NISCH gene_id:11188|Hs108|chr3 (1504) 9993 982.8 0 CCDS63651.1 NISCH gene_id:11188|Hs108|chr3 ( 515) 3292 333.8 8.4e-91 CCDS63652.1 NISCH gene_id:11188|Hs108|chr3 ( 583) 3284 333.1 1.6e-90 >>CCDS33767.1 NISCH gene_id:11188|Hs108|chr3 (1504 aa) initn: 9993 init1: 9993 opt: 9993 Z-score: 5243.1 bits: 982.8 E(32554): 0 Smith-Waterman score: 9993; 99.8% identity (99.9% similar) in 1504 aa overlap (1-1504:1-1504) 10 20 30 40 50 60 pF1KSD MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSIS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: CCDS33 TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSVS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 AAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD SDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD DFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD VLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD FYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 FYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD VKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCT 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD QPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 QPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD GSAQGSFADGQPAERRASNDQRPQEVPAEALAPAPVEVPAPAPAAASASGPAKTPAPAEA :: ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: CCDS33 GSPQGSFADGQPAERRASNDQRPQEVPAEALAPAPAEVPAPAPAAASASGPAKTPAPAEA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD STSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 STSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AIIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 AIIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD EPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTR 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD DSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD SEEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SEEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD FLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 FLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGH 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KSD DLMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DLMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPV 1450 1460 1470 1480 1490 1500 pF1KSD ELTG :::: CCDS33 ELTG >>CCDS63651.1 NISCH gene_id:11188|Hs108|chr3 (515 aa) initn: 3390 init1: 3292 opt: 3292 Z-score: 1743.7 bits: 333.8 E(32554): 8.4e-91 Smith-Waterman score: 3292; 99.6% identity (100.0% similar) in 512 aa overlap (1-512:1-512) 10 20 30 40 50 60 pF1KSD MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSIS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: CCDS63 TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSVS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGC :::::::::::::::::::::::::::::::. CCDS63 AAPCIRPSSSPPTVAPASASLPQPILSNQGILGDE 490 500 510 550 560 570 580 590 600 pF1KSD SDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQ >>CCDS63652.1 NISCH gene_id:11188|Hs108|chr3 (583 aa) initn: 3284 init1: 3284 opt: 3284 Z-score: 1738.8 bits: 333.1 E(32554): 1.6e-90 Smith-Waterman score: 3284; 99.8% identity (100.0% similar) in 510 aa overlap (1-510:1-510) 10 20 30 40 50 60 pF1KSD MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSIS ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: CCDS63 TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSVS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGC :::::::::::::::::::::::::::::: CCDS63 AAPCIRPSSSPPTVAPASASLPQPILSNQGNRVCILLLVEPHSPAWAPWLGWGWGRGAST 490 500 510 520 530 540 1504 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:54:21 2016 done: Thu Nov 3 18:54:23 2016 Total Scan time: 6.460 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]