Result of FASTA (omim) for pF1KSDA0979
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0979, 1447 aa
  1>>>pF1KSDA0979 1447 - 1447 aa - 1447 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.7827+/-0.000518; mu= -1.1423+/- 0.032
 mean_var=376.1771+/-75.109, 0's: 0 Z-trim(117.3): 28  B-trim: 0 in 0/59
 Lambda= 0.066127
 statistics sampled from 29114 (29132) to 29114 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.342), width:  16
 Scan time: 16.000

The best scores are:                                      opt bits E(85289)
XP_016875939 (OMIM: 605333) PREDICTED: sister chro (1447) 9484 920.8       0
NP_055847 (OMIM: 605333) sister chromatid cohesion (1447) 9484 920.8       0
XP_016875937 (OMIM: 605333) PREDICTED: sister chro (1448) 9472 919.6       0
XP_005266355 (OMIM: 605333) PREDICTED: sister chro (1448) 9472 919.6       0
XP_016875938 (OMIM: 605333) PREDICTED: sister chro (1448) 9472 919.6       0
XP_011533302 (OMIM: 605333) PREDICTED: sister chro (1445) 9458 918.3       0
XP_011533301 (OMIM: 605333) PREDICTED: sister chro (1446) 9446 917.2       0
XP_016875940 (OMIM: 605333) PREDICTED: sister chro (1446) 9446 917.2       0
XP_016875941 (OMIM: 605333) PREDICTED: sister chro (1411) 8898 864.9       0
XP_016875942 (OMIM: 605333) PREDICTED: sister chro (1409) 8872 862.4       0
XP_011533304 (OMIM: 605333) PREDICTED: sister chro (1172) 7643 745.1 7.5e-214
XP_011511974 (OMIM: 613200) PREDICTED: sister chro (1337) 6089 596.9 3.5e-169
NP_001093869 (OMIM: 613200) sister chromatid cohes (1337) 6089 596.9 3.5e-169
XP_016863417 (OMIM: 613200) PREDICTED: sister chro (1337) 6089 596.9 3.5e-169
NP_001093870 (OMIM: 613200) sister chromatid cohes ( 600) 3186 319.6 4.6e-86


>>XP_016875939 (OMIM: 605333) PREDICTED: sister chromati  (1447 aa)
 initn: 9484 init1: 9484 opt: 9484  Z-score: 4908.4  bits: 920.8 E(85289):    0
Smith-Waterman score: 9484; 100.0% identity (100.0% similar) in 1447 aa overlap (1-1447:1-1447)

               10        20        30        40        50        60
pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KSD TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR
             1390      1400      1410      1420      1430      1440

              
pF1KSD SAKRERR
       :::::::
XP_016 SAKRERR
              

>>NP_055847 (OMIM: 605333) sister chromatid cohesion pro  (1447 aa)
 initn: 9484 init1: 9484 opt: 9484  Z-score: 4908.4  bits: 920.8 E(85289):    0
Smith-Waterman score: 9484; 100.0% identity (100.0% similar) in 1447 aa overlap (1-1447:1-1447)

               10        20        30        40        50        60
pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KSD TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR
             1390      1400      1410      1420      1430      1440

              
pF1KSD SAKRERR
       :::::::
NP_055 SAKRERR
              

>>XP_016875937 (OMIM: 605333) PREDICTED: sister chromati  (1448 aa)
 initn: 8892 init1: 8892 opt: 9472  Z-score: 4902.2  bits: 919.6 E(85289):    0
Smith-Waterman score: 9472; 99.9% identity (99.9% similar) in 1448 aa overlap (1-1447:1-1448)

               10        20        30        40        50        60
pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
             1270      1280      1290      1300      1310      1320

             1330      1340      1350       1360      1370         
pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQ-RAESPESSAIESTQSTPQKGRGRPS
       :::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQSRAESPESSAIESTQSTPQKGRGRPS
             1330      1340      1350      1360      1370      1380

    1380      1390      1400      1410      1420      1430         
pF1KSD KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR
             1390      1400      1410      1420      1430      1440

    1440       
pF1KSD RSAKRERR
       ::::::::
XP_016 RSAKRERR
               

>>XP_005266355 (OMIM: 605333) PREDICTED: sister chromati  (1448 aa)
 initn: 8892 init1: 8892 opt: 9472  Z-score: 4902.2  bits: 919.6 E(85289):    0
Smith-Waterman score: 9472; 99.9% identity (99.9% similar) in 1448 aa overlap (1-1447:1-1448)

               10        20        30        40        50        60
pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
             1270      1280      1290      1300      1310      1320

             1330      1340      1350       1360      1370         
pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQ-RAESPESSAIESTQSTPQKGRGRPS
       :::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_005 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQSRAESPESSAIESTQSTPQKGRGRPS
             1330      1340      1350      1360      1370      1380

    1380      1390      1400      1410      1420      1430         
pF1KSD KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR
             1390      1400      1410      1420      1430      1440

    1440       
pF1KSD RSAKRERR
       ::::::::
XP_005 RSAKRERR
               

>>XP_016875938 (OMIM: 605333) PREDICTED: sister chromati  (1448 aa)
 initn: 8892 init1: 8892 opt: 9472  Z-score: 4902.2  bits: 919.6 E(85289):    0
Smith-Waterman score: 9472; 99.9% identity (99.9% similar) in 1448 aa overlap (1-1447:1-1448)

               10        20        30        40        50        60
pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
             1270      1280      1290      1300      1310      1320

             1330      1340      1350       1360      1370         
pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQ-RAESPESSAIESTQSTPQKGRGRPS
       :::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQSRAESPESSAIESTQSTPQKGRGRPS
             1330      1340      1350      1360      1370      1380

    1380      1390      1400      1410      1420      1430         
pF1KSD KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR
             1390      1400      1410      1420      1430      1440

    1440       
pF1KSD RSAKRERR
       ::::::::
XP_016 RSAKRERR
               

>>XP_011533302 (OMIM: 605333) PREDICTED: sister chromati  (1445 aa)
 initn: 7949 init1: 7949 opt: 9458  Z-score: 4895.0  bits: 918.3 E(85289):    0
Smith-Waterman score: 9458; 99.9% identity (99.9% similar) in 1447 aa overlap (1-1447:1-1445)

               10        20        30        40        50        60
pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
       ::::::  ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDDSDL--SELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
               1210      1220      1230      1240      1250        

             1270      1280      1290      1300      1310      1320
pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
     1260      1270      1280      1290      1300      1310        

             1330      1340      1350      1360      1370      1380
pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK
     1320      1330      1340      1350      1360      1370        

             1390      1400      1410      1420      1430      1440
pF1KSD TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR
     1380      1390      1400      1410      1420      1430        

              
pF1KSD SAKRERR
       :::::::
XP_011 SAKRERR
     1440     

>>XP_011533301 (OMIM: 605333) PREDICTED: sister chromati  (1446 aa)
 initn: 7942 init1: 7942 opt: 9446  Z-score: 4888.8  bits: 917.2 E(85289):    0
Smith-Waterman score: 9446; 99.8% identity (99.8% similar) in 1448 aa overlap (1-1447:1-1446)

               10        20        30        40        50        60
pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
       ::::::  ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDDSDL--SELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
               1210      1220      1230      1240      1250        

             1270      1280      1290      1300      1310      1320
pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
     1260      1270      1280      1290      1300      1310        

             1330      1340      1350       1360      1370         
pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQ-RAESPESSAIESTQSTPQKGRGRPS
       :::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_011 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQSRAESPESSAIESTQSTPQKGRGRPS
     1320      1330      1340      1350      1360      1370        

    1380      1390      1400      1410      1420      1430         
pF1KSD KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR
     1380      1390      1400      1410      1420      1430        

    1440       
pF1KSD RSAKRERR
       ::::::::
XP_011 RSAKRERR
     1440      

>>XP_016875940 (OMIM: 605333) PREDICTED: sister chromati  (1446 aa)
 initn: 7942 init1: 7942 opt: 9446  Z-score: 4888.8  bits: 917.2 E(85289):    0
Smith-Waterman score: 9446; 99.8% identity (99.8% similar) in 1448 aa overlap (1-1447:1-1446)

               10        20        30        40        50        60
pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
       ::::::  ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDDSDL--SELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
               1210      1220      1230      1240      1250        

             1270      1280      1290      1300      1310      1320
pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
     1260      1270      1280      1290      1300      1310        

             1330      1340      1350       1360      1370         
pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQ-RAESPESSAIESTQSTPQKGRGRPS
       :::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQSRAESPESSAIESTQSTPQKGRGRPS
     1320      1330      1340      1350      1360      1370        

    1380      1390      1400      1410      1420      1430         
pF1KSD KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR
     1380      1390      1400      1410      1420      1430        

    1440       
pF1KSD RSAKRERR
       ::::::::
XP_016 RSAKRERR
     1440      

>>XP_016875941 (OMIM: 605333) PREDICTED: sister chromati  (1411 aa)
 initn: 8892 init1: 8892 opt: 8898  Z-score: 4606.4  bits: 864.9 E(85289):    0
Smith-Waterman score: 9159; 97.4% identity (97.4% similar) in 1447 aa overlap (1-1447:1-1411)

               10        20        30        40        50        60
pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK
       ::::::::::::::::::::::::::::::::::                          
XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQS-------------------------
             1330      1340      1350                              

             1390      1400      1410      1420      1430      1440
pF1KSD TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR
                  :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -----------RVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR
                   1360      1370      1380      1390      1400    

              
pF1KSD SAKRERR
       :::::::
XP_016 SAKRERR
         1410 

>>XP_016875942 (OMIM: 605333) PREDICTED: sister chromati  (1409 aa)
 initn: 8112 init1: 7942 opt: 8872  Z-score: 4593.0  bits: 862.4 E(85289):    0
Smith-Waterman score: 9133; 97.3% identity (97.3% similar) in 1447 aa overlap (1-1447:1-1409)

               10        20        30        40        50        60
pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
       ::::::  ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDDSDL--SELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
               1210      1220      1230      1240      1250        

             1270      1280      1290      1300      1310      1320
pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
     1260      1270      1280      1290      1300      1310        

             1330      1340      1350      1360      1370      1380
pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK
       ::::::::::::::::::::::::::::::::::                          
XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQS-------------------------
     1320      1330      1340      1350                            

             1390      1400      1410      1420      1430      1440
pF1KSD TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR
                  :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -----------RVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR
                     1360      1370      1380      1390      1400  

              
pF1KSD SAKRERR
       :::::::
XP_016 SAKRERR
              




1447 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 18:55:16 2016 done: Thu Nov  3 18:55:18 2016
 Total Scan time: 16.000 Total Display time:  0.950

Function used was FASTA [36.3.4 Apr, 2011]
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