FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0979, 1447 aa 1>>>pF1KSDA0979 1447 - 1447 aa - 1447 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.7827+/-0.000518; mu= -1.1423+/- 0.032 mean_var=376.1771+/-75.109, 0's: 0 Z-trim(117.3): 28 B-trim: 0 in 0/59 Lambda= 0.066127 statistics sampled from 29114 (29132) to 29114 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.342), width: 16 Scan time: 16.000 The best scores are: opt bits E(85289) XP_016875939 (OMIM: 605333) PREDICTED: sister chro (1447) 9484 920.8 0 NP_055847 (OMIM: 605333) sister chromatid cohesion (1447) 9484 920.8 0 XP_016875937 (OMIM: 605333) PREDICTED: sister chro (1448) 9472 919.6 0 XP_005266355 (OMIM: 605333) PREDICTED: sister chro (1448) 9472 919.6 0 XP_016875938 (OMIM: 605333) PREDICTED: sister chro (1448) 9472 919.6 0 XP_011533302 (OMIM: 605333) PREDICTED: sister chro (1445) 9458 918.3 0 XP_011533301 (OMIM: 605333) PREDICTED: sister chro (1446) 9446 917.2 0 XP_016875940 (OMIM: 605333) PREDICTED: sister chro (1446) 9446 917.2 0 XP_016875941 (OMIM: 605333) PREDICTED: sister chro (1411) 8898 864.9 0 XP_016875942 (OMIM: 605333) PREDICTED: sister chro (1409) 8872 862.4 0 XP_011533304 (OMIM: 605333) PREDICTED: sister chro (1172) 7643 745.1 7.5e-214 XP_011511974 (OMIM: 613200) PREDICTED: sister chro (1337) 6089 596.9 3.5e-169 NP_001093869 (OMIM: 613200) sister chromatid cohes (1337) 6089 596.9 3.5e-169 XP_016863417 (OMIM: 613200) PREDICTED: sister chro (1337) 6089 596.9 3.5e-169 NP_001093870 (OMIM: 613200) sister chromatid cohes ( 600) 3186 319.6 4.6e-86 >>XP_016875939 (OMIM: 605333) PREDICTED: sister chromati (1447 aa) initn: 9484 init1: 9484 opt: 9484 Z-score: 4908.4 bits: 920.8 E(85289): 0 Smith-Waterman score: 9484; 100.0% identity (100.0% similar) in 1447 aa overlap (1-1447:1-1447) 10 20 30 40 50 60 pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR 1390 1400 1410 1420 1430 1440 pF1KSD SAKRERR ::::::: XP_016 SAKRERR >>NP_055847 (OMIM: 605333) sister chromatid cohesion pro (1447 aa) initn: 9484 init1: 9484 opt: 9484 Z-score: 4908.4 bits: 920.8 E(85289): 0 Smith-Waterman score: 9484; 100.0% identity (100.0% similar) in 1447 aa overlap (1-1447:1-1447) 10 20 30 40 50 60 pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR 1390 1400 1410 1420 1430 1440 pF1KSD SAKRERR ::::::: NP_055 SAKRERR >>XP_016875937 (OMIM: 605333) PREDICTED: sister chromati (1448 aa) initn: 8892 init1: 8892 opt: 9472 Z-score: 4902.2 bits: 919.6 E(85289): 0 Smith-Waterman score: 9472; 99.9% identity (99.9% similar) in 1448 aa overlap (1-1447:1-1448) 10 20 30 40 50 60 pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQ-RAESPESSAIESTQSTPQKGRGRPS :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQSRAESPESSAIESTQSTPQKGRGRPS 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KSD KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR 1390 1400 1410 1420 1430 1440 1440 pF1KSD RSAKRERR :::::::: XP_016 RSAKRERR >>XP_005266355 (OMIM: 605333) PREDICTED: sister chromati (1448 aa) initn: 8892 init1: 8892 opt: 9472 Z-score: 4902.2 bits: 919.6 E(85289): 0 Smith-Waterman score: 9472; 99.9% identity (99.9% similar) in 1448 aa overlap (1-1447:1-1448) 10 20 30 40 50 60 pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQ-RAESPESSAIESTQSTPQKGRGRPS :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_005 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQSRAESPESSAIESTQSTPQKGRGRPS 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KSD KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR 1390 1400 1410 1420 1430 1440 1440 pF1KSD RSAKRERR :::::::: XP_005 RSAKRERR >>XP_016875938 (OMIM: 605333) PREDICTED: sister chromati (1448 aa) initn: 8892 init1: 8892 opt: 9472 Z-score: 4902.2 bits: 919.6 E(85289): 0 Smith-Waterman score: 9472; 99.9% identity (99.9% similar) in 1448 aa overlap (1-1447:1-1448) 10 20 30 40 50 60 pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQ-RAESPESSAIESTQSTPQKGRGRPS :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQSRAESPESSAIESTQSTPQKGRGRPS 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KSD KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR 1390 1400 1410 1420 1430 1440 1440 pF1KSD RSAKRERR :::::::: XP_016 RSAKRERR >>XP_011533302 (OMIM: 605333) PREDICTED: sister chromati (1445 aa) initn: 7949 init1: 7949 opt: 9458 Z-score: 4895.0 bits: 918.3 E(85289): 0 Smith-Waterman score: 9458; 99.9% identity (99.9% similar) in 1447 aa overlap (1-1447:1-1445) 10 20 30 40 50 60 pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDDSDL--SELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1260 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 1380 pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK 1320 1330 1340 1350 1360 1370 1390 1400 1410 1420 1430 1440 pF1KSD TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR 1380 1390 1400 1410 1420 1430 pF1KSD SAKRERR ::::::: XP_011 SAKRERR 1440 >>XP_011533301 (OMIM: 605333) PREDICTED: sister chromati (1446 aa) initn: 7942 init1: 7942 opt: 9446 Z-score: 4888.8 bits: 917.2 E(85289): 0 Smith-Waterman score: 9446; 99.8% identity (99.8% similar) in 1448 aa overlap (1-1447:1-1446) 10 20 30 40 50 60 pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDDSDL--SELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1260 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQ-RAESPESSAIESTQSTPQKGRGRPS :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_011 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQSRAESPESSAIESTQSTPQKGRGRPS 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KSD KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR 1380 1390 1400 1410 1420 1430 1440 pF1KSD RSAKRERR :::::::: XP_011 RSAKRERR 1440 >>XP_016875940 (OMIM: 605333) PREDICTED: sister chromati (1446 aa) initn: 7942 init1: 7942 opt: 9446 Z-score: 4888.8 bits: 917.2 E(85289): 0 Smith-Waterman score: 9446; 99.8% identity (99.8% similar) in 1448 aa overlap (1-1447:1-1446) 10 20 30 40 50 60 pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDDSDL--SELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1260 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQ-RAESPESSAIESTQSTPQKGRGRPS :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQSRAESPESSAIESTQSTPQKGRGRPS 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KSD KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRR 1380 1390 1400 1410 1420 1430 1440 pF1KSD RSAKRERR :::::::: XP_016 RSAKRERR 1440 >>XP_016875941 (OMIM: 605333) PREDICTED: sister chromati (1411 aa) initn: 8892 init1: 8892 opt: 8898 Z-score: 4606.4 bits: 864.9 E(85289): 0 Smith-Waterman score: 9159; 97.4% identity (97.4% similar) in 1447 aa overlap (1-1447:1-1411) 10 20 30 40 50 60 pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK :::::::::::::::::::::::::::::::::: XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQS------------------------- 1330 1340 1350 1390 1400 1410 1420 1430 1440 pF1KSD TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -----------RVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR 1360 1370 1380 1390 1400 pF1KSD SAKRERR ::::::: XP_016 SAKRERR 1410 >>XP_016875942 (OMIM: 605333) PREDICTED: sister chromati (1409 aa) initn: 8112 init1: 7942 opt: 8872 Z-score: 4593.0 bits: 862.4 E(85289): 0 Smith-Waterman score: 9133; 97.3% identity (97.3% similar) in 1447 aa overlap (1-1447:1-1409) 10 20 30 40 50 60 pF1KSD MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDDSDL--SELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1210 1220 1230 1240 1250 1270 1280 1290 1300 1310 1320 pF1KSD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1260 1270 1280 1290 1300 1310 1330 1340 1350 1360 1370 1380 pF1KSD PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK :::::::::::::::::::::::::::::::::: XP_016 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQS------------------------- 1320 1330 1340 1350 1390 1400 1410 1420 1430 1440 pF1KSD TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -----------RVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR 1360 1370 1380 1390 1400 pF1KSD SAKRERR ::::::: XP_016 SAKRERR 1447 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:55:16 2016 done: Thu Nov 3 18:55:18 2016 Total Scan time: 16.000 Total Display time: 0.950 Function used was FASTA [36.3.4 Apr, 2011]