FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0980, 1382 aa 1>>>pF1KSDA0980 1382 - 1382 aa - 1382 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.2380+/-0.000524; mu= -2.6333+/- 0.033 mean_var=429.0287+/-89.227, 0's: 0 Z-trim(119.6): 109 B-trim: 1210 in 3/52 Lambda= 0.061920 statistics sampled from 33780 (33902) to 33780 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.397), width: 16 Scan time: 20.350 The best scores are: opt bits E(85289) NP_079452 (OMIM: 609580) ninein-like protein isofo (1382) 9058 825.2 0 XP_011527492 (OMIM: 609580) PREDICTED: ninein-like (1387) 9038 823.4 0 XP_016883223 (OMIM: 609580) PREDICTED: ninein-like ( 896) 5812 535.0 9.3e-151 XP_011527489 (OMIM: 609580) PREDICTED: ninein-like (1465) 4971 460.1 5.4e-128 NP_001305155 (OMIM: 609580) ninein-like protein is (1033) 4837 448.0 1.7e-124 XP_011527495 (OMIM: 609580) PREDICTED: ninein-like (1038) 4817 446.2 5.9e-124 XP_011527496 (OMIM: 609580) PREDICTED: ninein-like (1020) 4249 395.4 1.1e-108 XP_011527494 (OMIM: 609580) PREDICTED: ninein-like (1082) 4249 395.5 1.1e-108 XP_016883222 (OMIM: 609580) PREDICTED: ninein-like (1290) 4249 395.5 1.3e-108 XP_011527493 (OMIM: 609580) PREDICTED: ninein-like (1295) 4249 395.5 1.3e-108 XP_011527491 (OMIM: 609580) PREDICTED: ninein-like (1454) 4249 395.6 1.4e-108 XP_011527490 (OMIM: 609580) PREDICTED: ninein-like (1454) 4249 395.6 1.4e-108 XP_011527488 (OMIM: 609580) PREDICTED: ninein-like (1470) 4249 395.6 1.4e-108 XP_016883221 (OMIM: 609580) PREDICTED: ninein-like (1470) 4249 395.6 1.4e-108 XP_011527500 (OMIM: 609580) PREDICTED: ninein-like ( 811) 4232 393.8 2.7e-108 XP_016883224 (OMIM: 609580) PREDICTED: ninein-like ( 829) 4232 393.8 2.7e-108 XP_011527499 (OMIM: 609580) PREDICTED: ninein-like ( 829) 4232 393.8 2.7e-108 XP_011527497 (OMIM: 609580) PREDICTED: ninein-like ( 963) 4232 393.9 3e-108 NP_057434 (OMIM: 608684,614851) ninein isoform 6 [ (1377) 1220 125.0 3.8e-27 XP_011535124 (OMIM: 608684,614851) PREDICTED: nine (1450) 1214 124.5 5.8e-27 NP_891989 (OMIM: 608684,614851) ninein isoform 1 [ (2046) 1175 121.1 8.2e-26 NP_891991 (OMIM: 608684,614851) ninein isoform 5 [ (2090) 1175 121.2 8.3e-26 NP_065972 (OMIM: 608684,614851) ninein isoform 2 [ (2133) 1175 121.2 8.5e-26 XP_011535121 (OMIM: 608684,614851) PREDICTED: nine (2076) 1173 121.0 9.4e-26 XP_011535125 (OMIM: 608684,614851) PREDICTED: nine (2096) 1173 121.0 9.5e-26 XP_011535119 (OMIM: 608684,614851) PREDICTED: nine (2163) 1173 121.0 9.7e-26 XP_016858403 (OMIM: 615776) PREDICTED: rootletin i (1894) 349 47.3 0.0013 XP_006711121 (OMIM: 615776) PREDICTED: rootletin i (1945) 349 47.3 0.0013 XP_011540772 (OMIM: 615776) PREDICTED: rootletin i (1958) 349 47.3 0.0013 XP_016858402 (OMIM: 615776) PREDICTED: rootletin i (2012) 349 47.3 0.0013 NP_055490 (OMIM: 615776) rootletin [Homo sapiens] (2017) 349 47.3 0.0013 XP_011540770 (OMIM: 615776) PREDICTED: rootletin i (2019) 349 47.3 0.0013 XP_016873319 (OMIM: 164009,612376) PREDICTED: nucl (2101) 320 44.8 0.0082 NP_001273490 (OMIM: 164009,612376) nuclear mitotic (2101) 320 44.8 0.0082 XP_011543368 (OMIM: 164009,612376) PREDICTED: nucl (2101) 320 44.8 0.0082 XP_016873320 (OMIM: 164009,612376) PREDICTED: nucl (2101) 320 44.8 0.0082 XP_011543367 (OMIM: 164009,612376) PREDICTED: nucl (2119) 320 44.8 0.0083 >>NP_079452 (OMIM: 609580) ninein-like protein isoform 1 (1382 aa) initn: 9058 init1: 9058 opt: 9058 Z-score: 4392.3 bits: 825.2 E(85289): 0 Smith-Waterman score: 9058; 100.0% identity (100.0% similar) in 1382 aa overlap (1-1382:1-1382) 10 20 30 40 50 60 pF1KSD MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFAR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 VNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 ATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 EDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 LFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQSLDFSVDEKVNLLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 SLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQSLDFSVDEKVNLLELT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD WALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 WALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD MDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 AEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD LAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 LAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 GPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD MEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 MEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQRSEQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 GLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQRSEQLE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD LERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLVAGSGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 LERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLVAGSGQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD EGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAPAPASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 EGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAPAPASH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD GPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 GPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD PLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 PLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRG 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD SLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 SLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD NDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 NDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNR 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD QNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 QNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD LRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 LRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVA 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD ELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 ELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQF 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD EKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_079 EKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAAL 1330 1340 1350 1360 1370 1380 pF1KSD SV :: NP_079 SV >>XP_011527492 (OMIM: 609580) PREDICTED: ninein-like pro (1387 aa) initn: 6789 init1: 6789 opt: 9038 Z-score: 4382.7 bits: 823.4 E(85289): 0 Smith-Waterman score: 9038; 99.6% identity (99.6% similar) in 1387 aa overlap (1-1382:1-1387) 10 20 30 40 50 60 pF1KSD MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFAR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTS 250 260 270 280 290 300 310 320 330 340 350 pF1KSD SLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQ-----SLDFSVDEKVN :::::::::::::::::::::::::::::::::::::::::::: ::::::::::: XP_011 SLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQACCFQSLDFSVDEKVN 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD LLELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD EFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWD 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD VGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD QSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRR 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD QLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD KERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCC 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD TQALCGLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQALCGLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQR 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD SEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLV 790 800 810 820 830 840 840 850 860 870 880 890 pF1KSD AGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAP 850 860 870 880 890 900 900 910 920 930 940 950 pF1KSD APASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQP 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KSD RMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVE 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KSD VARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKH 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KSD VDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEM 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KSD EVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQS 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KSD DQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVP 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KSD QDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDK 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KSD LKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRI 1330 1340 1350 1360 1370 1380 1380 pF1KSD APAALSV ::::::: XP_011 APAALSV >>XP_016883223 (OMIM: 609580) PREDICTED: ninein-like pro (896 aa) initn: 5812 init1: 5812 opt: 5812 Z-score: 2827.5 bits: 535.0 E(85289): 9.3e-151 Smith-Waterman score: 5812; 99.9% identity (100.0% similar) in 888 aa overlap (495-1382:9-896) 470 480 490 500 510 520 pF1KSD AHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKD .::::::::::::::::::::::::::::: XP_016 MTHGLSEHRENSRLQKEIVEVVEKLSDSERLALKLQKD 10 20 30 530 540 550 560 570 580 pF1KSD LEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRH 40 50 60 70 80 90 590 600 610 620 630 640 pF1KSD SPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYE 100 110 120 130 140 150 650 660 670 680 690 700 pF1KSD REIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGP 160 170 180 190 200 210 710 720 730 740 750 760 pF1KSD EPEQMGLAPCCTQALCGLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPEQMGLAPCCTQALCGLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEP 220 230 240 250 260 270 770 780 790 800 810 820 pF1KSD PQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEA 280 290 300 310 320 330 830 840 850 860 870 880 pF1KSD EMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQD 340 350 360 370 380 390 890 900 910 920 930 940 pF1KSD TEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLL 400 410 420 430 440 450 950 960 970 980 990 1000 pF1KSD GTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGA 460 470 480 490 500 510 1010 1020 1030 1040 1050 1060 pF1KSD LEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLH 520 530 540 550 560 570 1070 1080 1090 1100 1110 1120 pF1KSD LEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVL 580 590 600 610 620 630 1130 1140 1150 1160 1170 1180 pF1KSD KKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSL 640 650 660 670 680 690 1190 1200 1210 1220 1230 1240 pF1KSD EEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQ 700 710 720 730 740 750 1250 1260 1270 1280 1290 1300 pF1KSD AQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKN 760 770 780 790 800 810 1310 1320 1330 1340 1350 1360 pF1KSD MEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEK 820 830 840 850 860 870 1370 1380 pF1KSD VRALNKLVSRIAPAALSV :::::::::::::::::: XP_016 VRALNKLVSRIAPAALSV 880 890 >>XP_011527489 (OMIM: 609580) PREDICTED: ninein-like pro (1465 aa) initn: 4919 init1: 4833 opt: 4971 Z-score: 2418.9 bits: 460.1 E(85289): 5.4e-128 Smith-Waterman score: 8708; 95.3% identity (95.3% similar) in 1414 aa overlap (1-1347:17-1430) 10 20 30 40 pF1KSD MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQ :::::::::::::::::::::::::::::::::::::::::::: XP_011 MKKKLKRPLNCAACYGMDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD LPVLLQTLLGNDHFARVNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPVLLQTLLGNDHFARVNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVN 70 80 90 100 110 120 110 120 130 140 150 160 pF1KSD GSKWYGRRSRPELCDAATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSKWYGRRSRPELCDAATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEA 130 140 150 160 170 180 170 180 190 200 210 220 pF1KSD QNELFEAQGQLQTWDSEDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QNELFEAQGQLQTWDSEDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVV 190 200 210 220 230 240 230 240 250 260 270 280 pF1KSD CQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KSD HYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQ 310 320 330 340 350 360 350 360 370 380 390 400 pF1KSD SLDFSVDEKVNLLELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLDFSVDEKVNLLELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKAR 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD QDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQ 430 440 450 460 470 480 470 480 490 500 510 520 pF1KSD AHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKD 490 500 510 520 530 540 530 540 550 560 570 580 pF1KSD LEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRH 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD SPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYE 610 620 630 640 650 660 650 660 670 680 690 700 pF1KSD REIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGP 670 680 690 700 710 720 710 720 730 pF1KSD EPEQMGLAPCCTQALCGLALRHHSHLQQIRR----------------------------- ::::::::::::::::::::::::::::::: XP_011 EPEQMGLAPCCTQALCGLALRHHSHLQQIRRGSAWSSQTGCCSAGTHCPVESIGPGLEED 730 740 750 760 770 780 740 750 pF1KSD --------------------------------------EAEAELSGELSGLGALPARRDL :::::::::::::::::::::: XP_011 GPSHHTGQATPSLTESHLSGRMRWLTPVISTLGGQGGREAEAELSGELSGLGALPARRDL 790 800 810 820 830 840 760 770 780 790 800 810 pF1KSD TLELEEPPQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLELEEPPQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRV 850 860 870 880 890 900 820 830 840 850 860 870 pF1KSD DGPSLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGPSLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGP 910 920 930 940 950 960 880 890 900 910 920 930 pF1KSD RRRQAQDTEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRRQAQDTEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPG 970 980 990 1000 1010 1020 940 950 960 970 980 990 pF1KSD ARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQ 1030 1040 1050 1060 1070 1080 1000 1010 1020 1030 1040 1050 pF1KSD QARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDD 1090 1100 1110 1120 1130 1140 1060 1070 1080 1090 1100 1110 pF1KSD METKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 METKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQ 1150 1160 1170 1180 1190 1200 1120 1130 1140 1150 1160 1170 pF1KSD RKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTI 1210 1220 1230 1240 1250 1260 1180 1190 1200 1210 1220 1230 pF1KSD QMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAH 1270 1280 1290 1300 1310 1320 1240 1250 1260 1270 1280 1290 pF1KSD LRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEE 1330 1340 1350 1360 1370 1380 1300 1310 1320 1330 1340 1350 pF1KSD AEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQ :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQ 1390 1400 1410 1420 1430 1440 1360 1370 1380 pF1KSD SRLLEEKVRALNKLVSRIAPAALSV XP_011 SRLLEEKVRALNKLVSRIAPAALSV 1450 1460 >>NP_001305155 (OMIM: 609580) ninein-like protein isofor (1033 aa) initn: 4898 init1: 4829 opt: 4837 Z-score: 2356.1 bits: 448.0 E(85289): 1.7e-124 Smith-Waterman score: 5987; 74.7% identity (74.7% similar) in 1382 aa overlap (1-1382:1-1033) 10 20 30 40 50 60 pF1KSD MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFAR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQSLDFSVDEKVNLLELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQSLDFSVDEKVNLLELT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD WALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD MDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD LAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD MEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD GLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQRSEQLE :::::::::::::: NP_001 GLALRHHSHLQQIR---------------------------------------------- 730 790 800 810 820 830 840 pF1KSD LERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLVAGSGQ NP_001 ------------------------------------------------------------ 850 860 870 880 890 900 pF1KSD EGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAPAPASH NP_001 ------------------------------------------------------------ 910 920 930 940 950 960 pF1KSD GPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEP NP_001 ------------------------------------------------------------ 970 980 990 1000 1010 1020 pF1KSD PLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRG NP_001 ------------------------------------------------------------ 1030 1040 1050 1060 1070 1080 pF1KSD SLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRE NP_001 ------------------------------------------------------------ 1090 1100 1110 1120 1130 1140 pF1KSD NDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNR ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---LEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNR 740 750 760 770 780 790 1150 1160 1170 1180 1190 1200 pF1KSD QNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQK 800 810 820 830 840 850 1210 1220 1230 1240 1250 1260 pF1KSD LRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVA 860 870 880 890 900 910 1270 1280 1290 1300 1310 1320 pF1KSD ELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQF 920 930 940 950 960 970 1330 1340 1350 1360 1370 1380 pF1KSD EKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAAL 980 990 1000 1010 1020 1030 pF1KSD SV :: NP_001 SV >>XP_011527495 (OMIM: 609580) PREDICTED: ninein-like pro (1038 aa) initn: 4894 init1: 2559 opt: 4817 Z-score: 2346.4 bits: 446.2 E(85289): 5.9e-124 Smith-Waterman score: 5967; 74.5% identity (74.5% similar) in 1387 aa overlap (1-1382:1-1038) 10 20 30 40 50 60 pF1KSD MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFAR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD VNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD ATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTS 250 260 270 280 290 300 310 320 330 340 350 pF1KSD SLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQ-----SLDFSVDEKVN :::::::::::::::::::::::::::::::::::::::::::: ::::::::::: XP_011 SLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQACCFQSLDFSVDEKVN 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD LLELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD EFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWD 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD VGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEP 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD QSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRR 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD QLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD KERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCC 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD TQALCGLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQR ::::::::::::::::::: XP_011 TQALCGLALRHHSHLQQIR----------------------------------------- 730 780 790 800 810 820 830 pF1KSD SEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLV XP_011 ------------------------------------------------------------ 840 850 860 870 880 890 pF1KSD AGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAP XP_011 ------------------------------------------------------------ 900 910 920 930 940 950 pF1KSD APASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQP XP_011 ------------------------------------------------------------ 960 970 980 990 1000 1010 pF1KSD RMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVE XP_011 ------------------------------------------------------------ 1020 1030 1040 1050 1060 1070 pF1KSD VARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKH XP_011 ------------------------------------------------------------ 1080 1090 1100 1110 1120 1130 pF1KSD VDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEM :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 --------LEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEM 740 750 760 770 780 790 1140 1150 1160 1170 1180 1190 pF1KSD EVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQS 800 810 820 830 840 850 1200 1210 1220 1230 1240 1250 pF1KSD DQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVP 860 870 880 890 900 910 1260 1270 1280 1290 1300 1310 pF1KSD QDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDK 920 930 940 950 960 970 1320 1330 1340 1350 1360 1370 pF1KSD LKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRI 980 990 1000 1010 1020 1030 1380 pF1KSD APAALSV ::::::: XP_011 APAALSV >>XP_011527496 (OMIM: 609580) PREDICTED: ninein-like pro (1020 aa) initn: 4232 init1: 4232 opt: 4249 Z-score: 2072.2 bits: 395.4 E(85289): 1.1e-108 Smith-Waterman score: 6040; 93.4% identity (93.4% similar) in 1012 aa overlap (438-1382:9-1020) 410 420 430 440 450 460 pF1KSD ERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHR :::::::::::::::::::::::::::::: XP_011 MGVMSRFLHLEQGYRERLSLLRSEVEAERELFWEQAHR 10 20 30 470 480 490 500 510 520 pF1KSD QRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEF 40 50 60 70 80 90 530 540 550 560 570 580 pF1KSD VLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPS 100 110 120 130 140 150 590 600 610 620 630 640 pF1KSD WSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREI 160 170 180 190 200 210 650 660 670 680 690 700 pF1KSD AALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPE 220 230 240 250 260 270 710 720 730 pF1KSD QMGLAPCCTQALCGLALRHHSHLQQIRR-------------------------------- :::::::::::::::::::::::::::: XP_011 QMGLAPCCTQALCGLALRHHSHLQQIRRGSAWSSQTGCCSAGTHCPVESIGPGLEEDGPS 280 290 300 310 320 330 740 750 760 pF1KSD -----------------------------------EAEAELSGELSGLGALPARRDLTLE ::::::::::::::::::::::::: XP_011 HHTGQATPSLTESHLSGRMRWLTPVISTLGGQGGREAEAELSGELSGLGALPARRDLTLE 340 350 360 370 380 390 770 780 790 800 810 820 pF1KSD LEEPPQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEEPPQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGP 400 410 420 430 440 450 830 840 850 860 870 880 pF1KSD SLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRR 460 470 480 490 500 510 890 900 910 920 930 940 pF1KSD QAQDTEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QAQDTEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARE 520 530 540 550 560 570 950 960 970 980 990 1000 pF1KSD LPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQAR 580 590 600 610 620 630 1010 1020 1030 1040 1050 1060 pF1KSD AEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMET 640 650 660 670 680 690 1070 1080 1090 1100 1110 1120 pF1KSD KLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKE 700 710 720 730 740 750 1130 1140 1150 1160 1170 1180 pF1KSD IEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQML 760 770 780 790 800 810 1190 1200 1210 1220 1230 1240 pF1KSD TQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRL 820 830 840 850 860 870 1250 1260 1270 1280 1290 1300 pF1KSD RQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEM 880 890 900 910 920 930 1310 1320 1330 1340 1350 1360 pF1KSD ILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRL 940 950 960 970 980 990 1370 1380 pF1KSD LEEKVRALNKLVSRIAPAALSV :::::::::::::::::::::: XP_011 LEEKVRALNKLVSRIAPAALSV 1000 1010 1020 >>XP_011527494 (OMIM: 609580) PREDICTED: ninein-like pro (1082 aa) initn: 4232 init1: 4232 opt: 4249 Z-score: 2071.9 bits: 395.5 E(85289): 1.1e-108 Smith-Waterman score: 6492; 93.8% identity (93.8% similar) in 1082 aa overlap (368-1382:1-1082) 340 350 360 370 380 390 pF1KSD NGREILQSLDFSVDEKVNLLELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLA :::::::::::::::::::::::::::::: XP_011 MTVDSAVQQAALACYHQELSYQQGQVEQLA 10 20 30 400 410 420 430 440 450 pF1KSD RERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAE 40 50 60 70 80 90 460 470 480 490 500 510 pF1KSD RELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERL 100 110 120 130 140 150 520 530 540 550 560 570 pF1KSD ALKLQKDLEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALKLQKDLEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWA 160 170 180 190 200 210 580 590 600 610 620 630 pF1KSD RLPKNRHSPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLPKNRHSPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLE 220 230 240 250 260 270 640 650 660 670 680 690 pF1KSD TKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQL 280 290 300 310 320 330 700 710 720 730 pF1KSD QDTARGPEPEQMGLAPCCTQALCGLALRHHSHLQQIRR---------------------- :::::::::::::::::::::::::::::::::::::: XP_011 QDTARGPEPEQMGLAPCCTQALCGLALRHHSHLQQIRRGSAWSSQTGCCSAGTHCPVESI 340 350 360 370 380 390 740 750 pF1KSD ---------------------------------------------EAEAELSGELSGLGA ::::::::::::::: XP_011 GPGLEEDGPSHHTGQATPSLTESHLSGRMRWLTPVISTLGGQGGREAEAELSGELSGLGA 400 410 420 430 440 450 760 770 780 790 800 810 pF1KSD LPARRDLTLELEEPPQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPARRDLTLELEEPPQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELE 460 470 480 490 500 510 820 830 840 850 860 870 pF1KSD LARGKRVDGPSLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LARGKRVDGPSLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESE 520 530 540 550 560 570 880 890 900 910 920 930 pF1KSD EAAGAGPRRRQAQDTEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAAGAGPRRRQAQDTEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASA 580 590 600 610 620 630 940 950 960 970 980 990 pF1KSD AGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGT 640 650 660 670 680 690 1000 1010 1020 1030 1040 1050 pF1KSD QEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIA 700 710 720 730 740 750 1060 1070 1080 1090 1100 1110 pF1KSD LEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAA 760 770 780 790 800 810 1120 1130 1140 1150 1160 1170 pF1KSD ESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQN 820 830 840 850 860 870 1180 1190 1200 1210 1220 1230 pF1KSD EEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQ 880 890 900 910 920 930 1240 1250 1260 1270 1280 1290 pF1KSD DQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKA 940 950 960 970 980 990 1300 1310 1320 1330 1340 1350 pF1KSD TEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEK 1000 1010 1020 1030 1040 1050 1360 1370 1380 pF1KSD QRGAEKQSRLLEEKVRALNKLVSRIAPAALSV :::::::::::::::::::::::::::::::: XP_011 QRGAEKQSRLLEEKVRALNKLVSRIAPAALSV 1060 1070 1080 >>XP_016883222 (OMIM: 609580) PREDICTED: ninein-like pro (1290 aa) initn: 4232 init1: 4232 opt: 4249 Z-score: 2071.0 bits: 395.5 E(85289): 1.3e-108 Smith-Waterman score: 7797; 94.7% identity (94.8% similar) in 1278 aa overlap (172-1382:13-1290) 150 160 170 180 190 200 pF1KSD RSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDSEDFGSPQKSCSPSFDTPESQI .::::::::::::::::::::::::::::: XP_016 MMPARVKKGAPQKGQLQTWDSEDFGSPQKSCSPSFDTPESQI 10 20 30 40 210 220 230 240 250 260 pF1KSD RGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLG 50 60 70 80 90 100 270 280 290 300 310 320 pF1KSD LFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGF 110 120 130 140 150 160 330 340 350 360 370 380 pF1KSD AFPDQVLAMWTQEGIQNGREILQSLDFSVDEKVNLLELTWALDNELMTVDSAVQQAALAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFPDQVLAMWTQEGIQNGREILQSLDFSVDEKVNLLELTWALDNELMTVDSAVQQAALAC 170 180 190 200 210 220 390 400 410 420 430 440 pF1KSD YHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQ 230 240 250 260 270 280 450 460 470 480 490 500 pF1KSD GYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQ 290 300 310 320 330 340 510 520 530 540 550 560 pF1KSD KEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDL 350 360 370 380 390 400 570 580 590 600 610 620 pF1KSD QDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELM 410 420 430 440 450 460 630 640 650 660 670 680 pF1KSD MEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQKADLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQKADLEE 470 480 490 500 510 520 690 700 710 720 730 pF1KSD LHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALCGLALRHHSHLQQIRR------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALCGLALRHHSHLQQIRRGSAWSS 530 540 550 560 570 580 pF1KSD ------------------------------------------------------------ XP_016 QTGCCSAGTHCPVESIGPGLEEDGPSHHTGQATPSLTESHLSGRMRWLTPVISTLGGQGG 590 600 610 620 630 640 740 750 760 770 780 790 pF1KSD -EAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQRSEQLELERALKLQPCASEK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQRSEQLELERALKLQPCASEK 650 660 670 680 690 700 800 810 820 830 840 850 pF1KSD RAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCG 710 720 730 740 750 760 860 870 880 890 900 910 pF1KSD ERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAPAPASHGPSERWSRMQPCGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAPAPASHGPSERWSRMQPCGV 770 780 790 800 810 820 920 930 940 950 960 970 pF1KSD DGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAER 830 840 850 860 870 880 980 990 1000 1010 1020 1030 pF1KSD LQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGS 890 900 910 920 930 940 1040 1050 1060 1070 1080 1090 pF1KSD WQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENT 950 960 970 980 990 1000 1100 1110 1120 1130 1140 1150 pF1KSD LLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNV 1010 1020 1030 1040 1050 1060 1160 1170 1180 1190 1200 1210 pF1KSD RVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQS 1070 1080 1090 1100 1110 1120 1220 1230 1240 1250 1260 1270 pF1KSD LQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQAR 1130 1140 1150 1160 1170 1180 1280 1290 1300 1310 1320 1330 pF1KSD RRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELY 1190 1200 1210 1220 1230 1240 1340 1350 1360 1370 1380 pF1KSD VENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV 1250 1260 1270 1280 1290 >>XP_011527493 (OMIM: 609580) PREDICTED: ninein-like pro (1295 aa) initn: 5416 init1: 4232 opt: 4249 Z-score: 2071.0 bits: 395.5 E(85289): 1.3e-108 Smith-Waterman score: 7777; 94.3% identity (94.4% similar) in 1283 aa overlap (172-1382:13-1295) 150 160 170 180 190 200 pF1KSD RSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDSEDFGSPQKSCSPSFDTPESQI .::::::::::::::::::::::::::::: XP_011 MMPARVKKGAPQKGQLQTWDSEDFGSPQKSCSPSFDTPESQI 10 20 30 40 210 220 230 240 250 260 pF1KSD RGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLG 50 60 70 80 90 100 270 280 290 300 310 320 pF1KSD LFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGF 110 120 130 140 150 160 330 340 350 360 370 pF1KSD AFPDQVLAMWTQEGIQNGREILQ-----SLDFSVDEKVNLLELTWALDNELMTVDSAVQQ ::::::::::::::::::::::: :::::::::::::::::::::::::::::::: XP_011 AFPDQVLAMWTQEGIQNGREILQACCFQSLDFSVDEKVNLLELTWALDNELMTVDSAVQQ 170 180 190 200 210 220 380 390 400 410 420 430 pF1KSD AALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKI 230 240 250 260 270 280 440 450 460 470 480 490 pF1KSD KHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKE 290 300 310 320 330 340 500 510 520 530 540 550 pF1KSD NSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAELLAQEERFAAVLKEYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAELLAQEERFAAVLKEYEL 350 360 370 380 390 400 560 570 580 590 600 610 pF1KSD KCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGLGPAGISFLGNSAPVSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGLGPAGISFLGNSAPVSI 410 420 430 440 450 460 620 630 640 650 660 670 pF1KSD ETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQK 470 480 490 500 510 520 680 690 700 710 720 730 pF1KSD ADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALCGLALRHHSHLQQIRR- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALCGLALRHHSHLQQIRRG 530 540 550 560 570 580 pF1KSD ------------------------------------------------------------ XP_011 SAWSSQTGCCSAGTHCPVESIGPGLEEDGPSHHTGQATPSLTESHLSGRMRWLTPVISTL 590 600 610 620 630 640 740 750 760 770 780 pF1KSD ------EAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQRSEQLELERALKLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGQGGREAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQRSEQLELERALKLQP 650 660 670 680 690 700 790 800 810 820 830 840 pF1KSD CASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLVAGSGQEGTRGLLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLVAGSGQEGTRGLLPL 710 720 730 740 750 760 850 860 870 880 890 900 pF1KSD RPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAPAPASHGPSERWSRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAPAPASHGPSERWSRM 770 780 790 800 810 820 910 920 930 940 950 960 pF1KSD QPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCR 830 840 850 860 870 880 970 980 990 1000 1010 1020 pF1KSD GQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLA 890 900 910 920 930 940 1030 1040 1050 1060 1070 1080 pF1KSD DPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRL 950 960 970 980 990 1000 1090 1100 1110 1120 1130 1140 pF1KSD SEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQL 1010 1020 1030 1040 1050 1060 1150 1160 1170 1180 1190 1200 pF1KSD SQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLN 1070 1080 1090 1100 1110 1120 1210 1220 1230 1240 1250 1260 pF1KSD QEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQ 1130 1140 1150 1160 1170 1180 1270 1280 1290 1300 1310 1320 pF1KSD GEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLL 1190 1200 1210 1220 1230 1240 1330 1340 1350 1360 1370 1380 pF1KSD LKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV 1250 1260 1270 1280 1290 1382 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:31:58 2016 done: Thu Nov 3 04:32:01 2016 Total Scan time: 20.350 Total Display time: 0.590 Function used was FASTA [36.3.4 Apr, 2011]