FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0992, 672 aa 1>>>pF1KSDA0992 672 - 672 aa - 672 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 16.3611+/-0.000536; mu= -31.0693+/- 0.033 mean_var=753.6036+/-158.423, 0's: 0 Z-trim(124.1): 135 B-trim: 2090 in 1/56 Lambda= 0.046720 statistics sampled from 44989 (45163) to 44989 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.788), E-opt: 0.2 (0.53), width: 16 Scan time: 14.100 The best scores are: opt bits E(85289) NP_001159582 (OMIM: 606856,608092) palladin isofor ( 672) 4603 325.7 3.5e-88 XP_011530071 (OMIM: 606856,608092) PREDICTED: pall (1451) 4603 326.0 6.2e-88 XP_016863399 (OMIM: 606856,608092) PREDICTED: pall (1398) 4239 301.4 1.5e-80 NP_001159581 (OMIM: 606856,608092) palladin isofor ( 777) 3423 246.2 3.4e-64 XP_011530076 (OMIM: 606856,608092) PREDICTED: pall (1227) 3423 246.4 4.8e-64 NP_057165 (OMIM: 606856,608092) palladin isoform 2 (1106) 3059 221.8 1.1e-56 XP_011530077 (OMIM: 606856,608092) PREDICTED: pall (1018) 3046 220.9 1.9e-56 XP_005262923 (OMIM: 606856,608092) PREDICTED: pall (1018) 3046 220.9 1.9e-56 XP_005262918 (OMIM: 606856,608092) PREDICTED: pall (1400) 3046 221.0 2.4e-56 XP_011530070 (OMIM: 606856,608092) PREDICTED: pall (1468) 3046 221.0 2.5e-56 XP_011530075 (OMIM: 606856,608092) PREDICTED: pall (1244) 2953 214.7 1.7e-54 XP_011530072 (OMIM: 606856,608092) PREDICTED: pall (1415) 2682 196.5 5.8e-49 NP_001159580 (OMIM: 606856,608092) palladin isofor (1123) 2589 190.1 3.7e-47 XP_011530073 (OMIM: 606856,608092) PREDICTED: pall (1377) 2444 180.4 3.8e-44 XP_011530074 (OMIM: 606856,608092) PREDICTED: pall (1344) 2420 178.8 1.2e-43 NP_001243197 (OMIM: 608517,615248) myopalladin iso (1026) 1876 142.0 1e-32 NP_115967 (OMIM: 608517,615248) myopalladin isofor (1320) 1876 142.1 1.2e-32 XP_016872323 (OMIM: 608517,615248) PREDICTED: myop (1320) 1876 142.1 1.2e-32 NP_001243196 (OMIM: 608517,615248) myopalladin iso (1320) 1876 142.1 1.2e-32 XP_016872322 (OMIM: 608517,615248) PREDICTED: myop (1346) 1876 142.1 1.3e-32 NP_001129412 (OMIM: 159000,182920,604103,609200) m ( 314) 958 79.8 1.8e-14 NP_001287840 (OMIM: 159000,182920,604103,609200) m ( 383) 961 80.0 1.8e-14 NP_006781 (OMIM: 159000,182920,604103,609200) myot ( 498) 961 80.1 2.2e-14 XP_016865549 (OMIM: 159000,182920,604103,609200) P ( 303) 948 79.1 2.7e-14 XP_016865550 (OMIM: 159000,182920,604103,609200) P ( 303) 948 79.1 2.7e-14 XP_016865551 (OMIM: 159000,182920,604103,609200) P ( 303) 948 79.1 2.7e-14 NP_596870 (OMIM: 188840,600334,603689,604145,60880 (5604) 469 47.8 0.0013 NP_003310 (OMIM: 188840,600334,603689,604145,60880 (26926) 469 48.3 0.0044 XP_016860312 (OMIM: 188840,600334,603689,604145,60 (26973) 469 48.3 0.0044 NP_597676 (OMIM: 188840,600334,603689,604145,60880 (27051) 469 48.3 0.0044 NP_597681 (OMIM: 188840,600334,603689,604145,60880 (27118) 469 48.3 0.0044 XP_016860311 (OMIM: 188840,600334,603689,604145,60 (33101) 469 48.4 0.0052 NP_596869 (OMIM: 188840,600334,603689,604145,60880 (33423) 469 48.4 0.0052 XP_016860310 (OMIM: 188840,600334,603689,604145,60 (34087) 469 48.4 0.0053 XP_016860309 (OMIM: 188840,600334,603689,604145,60 (34088) 469 48.4 0.0053 NP_001243779 (OMIM: 188840,600334,603689,604145,60 (34350) 469 48.4 0.0053 XP_016860308 (OMIM: 188840,600334,603689,604145,60 (35622) 469 48.4 0.0055 NP_001254479 (OMIM: 188840,600334,603689,604145,60 (35991) 469 48.4 0.0055 >>NP_001159582 (OMIM: 606856,608092) palladin isoform 4 (672 aa) initn: 4603 init1: 4603 opt: 4603 Z-score: 1704.2 bits: 325.7 E(85289): 3.5e-88 Smith-Waterman score: 4603; 99.9% identity (100.0% similar) in 672 aa overlap (1-672:1-672) 10 20 30 40 50 60 pF1KSD MSALASRSAPAMQSSGSFNYARPKQFIAAQNLGPASGHGTPASSPSSSSLPSPMSPTPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSALASRSAPAMQSSGSFNYARPKQFIAAQNLGPASGHGTPASSPSSSSLPSPMSPTPRQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FGRAPVPPFAQPFGAEPEAPWGSSSPSPPPPPPPVFSPTAAFPVPDVFPLPPPPPPLPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGRAPVPPFAQPFGAEPEAPWGSSSPSPPPPPPPVFSPTAAFPVPDVFPLPPPPPPLPSP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GQASHCSSPATRFGHGQTPAAFLSALLPSQPPPAAVNALGLPKGVTPAGFPKKASRTARI :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_001 GQASHCSSPATRFGHSQTPAAFLSALLPSQPPPAAVNALGLPKGVTPAGFPKKASRTARI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHL 610 620 630 640 650 660 670 pF1KSD TLNTALVESEDL :::::::::::: NP_001 TLNTALVESEDL 670 >>XP_011530071 (OMIM: 606856,608092) PREDICTED: palladin (1451 aa) initn: 4603 init1: 4603 opt: 4603 Z-score: 1699.6 bits: 326.0 E(85289): 6.2e-88 Smith-Waterman score: 4603; 99.9% identity (100.0% similar) in 672 aa overlap (1-672:780-1451) 10 20 30 pF1KSD MSALASRSAPAMQSSGSFNYARPKQFIAAQ :::::::::::::::::::::::::::::: XP_011 PRSAPPSPPFPPPPAFPELAACTPPASPEPMSALASRSAPAMQSSGSFNYARPKQFIAAQ 750 760 770 780 790 800 40 50 60 70 80 90 pF1KSD NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP 810 820 830 840 850 860 100 110 120 130 140 150 pF1KSD PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHGQTPAAFLSALLPSQ :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_011 PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHSQTPAAFLSALLPSQ 870 880 890 900 910 920 160 170 180 190 200 210 pF1KSD PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN 930 940 950 960 970 980 220 230 240 250 260 270 pF1KSD GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPV 990 1000 1010 1020 1030 1040 280 290 300 310 320 330 pF1KSD DESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQI 1050 1060 1070 1080 1090 1100 340 350 360 370 380 390 pF1KSD SPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRS 1110 1120 1130 1140 1150 1160 400 410 420 430 440 450 pF1KSD PRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGL 1170 1180 1190 1200 1210 1220 460 470 480 490 500 510 pF1KSD PTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSL 1230 1240 1250 1260 1270 1280 520 530 540 550 560 570 pF1KSD ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRV 1290 1300 1310 1320 1330 1340 580 590 600 610 620 630 pF1KSD SMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKV 1350 1360 1370 1380 1390 1400 640 650 660 670 pF1KSD RPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL :::::::::::::::::::::::::::::::::::::::::: XP_011 RPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL 1410 1420 1430 1440 1450 >>XP_016863399 (OMIM: 606856,608092) PREDICTED: palladin (1398 aa) initn: 4684 init1: 4239 opt: 4239 Z-score: 1567.3 bits: 301.4 E(85289): 1.5e-80 Smith-Waterman score: 4239; 99.4% identity (99.7% similar) in 619 aa overlap (1-619:780-1398) 10 20 30 pF1KSD MSALASRSAPAMQSSGSFNYARPKQFIAAQ :::::::::::::::::::::::::::::: XP_016 PRSAPPSPPFPPPPAFPELAACTPPASPEPMSALASRSAPAMQSSGSFNYARPKQFIAAQ 750 760 770 780 790 800 40 50 60 70 80 90 pF1KSD NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP 810 820 830 840 850 860 100 110 120 130 140 150 pF1KSD PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHGQTPAAFLSALLPSQ :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_016 PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHSQTPAAFLSALLPSQ 870 880 890 900 910 920 160 170 180 190 200 210 pF1KSD PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN 930 940 950 960 970 980 220 230 240 250 260 270 pF1KSD GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPV 990 1000 1010 1020 1030 1040 280 290 300 310 320 330 pF1KSD DESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQI 1050 1060 1070 1080 1090 1100 340 350 360 370 380 390 pF1KSD SPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRS 1110 1120 1130 1140 1150 1160 400 410 420 430 440 450 pF1KSD PRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGL 1170 1180 1190 1200 1210 1220 460 470 480 490 500 510 pF1KSD PTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSL 1230 1240 1250 1260 1270 1280 520 530 540 550 560 570 pF1KSD ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRV 1290 1300 1310 1320 1330 1340 580 590 600 610 620 630 pF1KSD SMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKV ::::::::::::::::::::::::::::::::::::::::::::: . : XP_016 SMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISRH 1350 1360 1370 1380 1390 640 650 660 670 pF1KSD RPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL >>NP_001159581 (OMIM: 606856,608092) palladin isoform 3 (777 aa) initn: 3409 init1: 3409 opt: 3423 Z-score: 1273.5 bits: 246.2 E(85289): 3.4e-64 Smith-Waterman score: 3439; 93.5% identity (95.1% similar) in 555 aa overlap (118-672:233-777) 90 100 110 120 130 140 pF1KSD PPPPPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHGQTPAAFLSALL :: : . .. :. :::..:: NP_001 QQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLS--- 210 220 230 240 250 150 160 170 180 190 200 pF1KSD PSQPPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDL :.. :: :. :: ::::::::::::::::::::::::::::::::::::::: NP_001 PTKEPPPL---LAKPK----LGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDL 260 270 280 290 300 310 210 220 230 240 250 260 pF1KSD LNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLER 320 330 340 350 360 370 270 280 290 300 310 320 pF1KSD SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDG 380 390 400 410 420 430 330 340 350 360 370 380 pF1KSD KQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQR 440 450 460 470 480 490 390 400 410 420 430 440 pF1KSD GRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKV 500 510 520 530 540 550 450 460 470 480 490 500 pF1KSD SGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNS 560 570 580 590 600 610 510 520 530 540 550 560 pF1KSD FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 620 630 640 650 660 670 570 580 590 600 610 620 pF1KSD DRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKP 680 690 700 710 720 730 630 640 650 660 670 pF1KSD KKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL ::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL 740 750 760 770 >>XP_011530076 (OMIM: 606856,608092) PREDICTED: palladin (1227 aa) initn: 3409 init1: 3409 opt: 3423 Z-score: 1270.8 bits: 246.4 E(85289): 4.8e-64 Smith-Waterman score: 3439; 93.5% identity (95.1% similar) in 555 aa overlap (118-672:683-1227) 90 100 110 120 130 140 pF1KSD PPPPPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHGQTPAAFLSALL :: : . .. :. :::..:: XP_011 QQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLS--- 660 670 680 690 700 150 160 170 180 190 200 pF1KSD PSQPPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDL :.. :: :. :: ::::::::::::::::::::::::::::::::::::::: XP_011 PTKEPPPL---LAKPK----LGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDL 710 720 730 740 750 760 210 220 230 240 250 260 pF1KSD LNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLER 770 780 790 800 810 820 270 280 290 300 310 320 pF1KSD SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDG 830 840 850 860 870 880 330 340 350 360 370 380 pF1KSD KQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQR 890 900 910 920 930 940 390 400 410 420 430 440 pF1KSD GRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKV 950 960 970 980 990 1000 450 460 470 480 490 500 pF1KSD SGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNS 1010 1020 1030 1040 1050 1060 510 520 530 540 550 560 pF1KSD FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 1070 1080 1090 1100 1110 1120 570 580 590 600 610 620 pF1KSD DRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKP 1130 1140 1150 1160 1170 1180 630 640 650 660 670 pF1KSD KKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL ::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL 1190 1200 1210 1220 >>NP_057165 (OMIM: 606856,608092) palladin isoform 2 [Ho (1106 aa) initn: 3695 init1: 3045 opt: 3059 Z-score: 1138.8 bits: 221.8 E(85289): 1.1e-56 Smith-Waterman score: 3075; 92.2% identity (94.2% similar) in 502 aa overlap (118-619:615-1106) 90 100 110 120 130 140 pF1KSD PPPPPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHGQTPAAFLSALL :: : . .. :. :::..:: NP_057 QQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLS--- 590 600 610 620 630 640 150 160 170 180 190 200 pF1KSD PSQPPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDL :.. :: :. :: ::::::::::::::::::::::::::::::::::::::: NP_057 PTKEPPPL---LAKPK----LGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDL 650 660 670 680 690 210 220 230 240 250 260 pF1KSD LNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLER 700 710 720 730 740 750 270 280 290 300 310 320 pF1KSD SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDG 760 770 780 790 800 810 330 340 350 360 370 380 pF1KSD KQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQR 820 830 840 850 860 870 390 400 410 420 430 440 pF1KSD GRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 GRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKV 880 890 900 910 920 930 450 460 470 480 490 500 pF1KSD SGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNS 940 950 960 970 980 990 510 520 530 540 550 560 pF1KSD FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHST 1000 1010 1020 1030 1040 1050 570 580 590 600 610 620 pF1KSD DRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKP :::::::::::::::::::::::::::::::::::::::::::::::: . : NP_057 DRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISRH 1060 1070 1080 1090 1100 630 640 650 660 670 pF1KSD KKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL >>XP_011530077 (OMIM: 606856,608092) PREDICTED: palladin (1018 aa) initn: 2916 init1: 2916 opt: 3046 Z-score: 1134.6 bits: 220.9 E(85289): 1.9e-56 Smith-Waterman score: 4559; 97.4% identity (97.5% similar) in 689 aa overlap (1-672:330-1018) 10 20 30 pF1KSD MSALASRSAPAMQSSGSFNYARPKQFIAAQ :::::::::::::::::::::::::::::: XP_011 PRSAPPSPPFPPPPAFPELAACTPPASPEPMSALASRSAPAMQSSGSFNYARPKQFIAAQ 300 310 320 330 340 350 40 50 60 70 80 90 pF1KSD NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP 360 370 380 390 400 410 100 110 120 130 140 150 pF1KSD PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHGQTPAAFLSALLPSQ :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_011 PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHSQTPAAFLSALLPSQ 420 430 440 450 460 470 160 170 180 190 200 210 pF1KSD PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN 480 490 500 510 520 530 220 230 240 250 pF1KSD GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQ-----------------EYKVSSC :::::::::::::::::::::::::::::::::::: ::::::: XP_011 GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQDIGSPHASVGSPLDGQKEYKVSSC 540 550 560 570 580 590 260 270 280 290 300 310 pF1KSD EQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRV 600 610 620 630 640 650 320 330 340 350 360 370 pF1KSD AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRI 660 670 680 690 700 710 380 390 400 410 420 430 pF1KSD SCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL 720 730 740 750 760 770 440 450 460 470 480 490 pF1KSD TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 780 790 800 810 820 830 500 510 520 530 540 550 pF1KSD IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ 840 850 860 870 880 890 560 570 580 590 600 610 pF1KSD IFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLD 900 910 920 930 940 950 620 630 640 650 660 670 pF1KSD VYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL 960 970 980 990 1000 1010 >>XP_005262923 (OMIM: 606856,608092) PREDICTED: palladin (1018 aa) initn: 2916 init1: 2916 opt: 3046 Z-score: 1134.6 bits: 220.9 E(85289): 1.9e-56 Smith-Waterman score: 4559; 97.4% identity (97.5% similar) in 689 aa overlap (1-672:330-1018) 10 20 30 pF1KSD MSALASRSAPAMQSSGSFNYARPKQFIAAQ :::::::::::::::::::::::::::::: XP_005 PRSAPPSPPFPPPPAFPELAACTPPASPEPMSALASRSAPAMQSSGSFNYARPKQFIAAQ 300 310 320 330 340 350 40 50 60 70 80 90 pF1KSD NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP 360 370 380 390 400 410 100 110 120 130 140 150 pF1KSD PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHGQTPAAFLSALLPSQ :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_005 PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHSQTPAAFLSALLPSQ 420 430 440 450 460 470 160 170 180 190 200 210 pF1KSD PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN 480 490 500 510 520 530 220 230 240 250 pF1KSD GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQ-----------------EYKVSSC :::::::::::::::::::::::::::::::::::: ::::::: XP_005 GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQDIGSPHASVGSPLDGQKEYKVSSC 540 550 560 570 580 590 260 270 280 290 300 310 pF1KSD EQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRV 600 610 620 630 640 650 320 330 340 350 360 370 pF1KSD AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRI 660 670 680 690 700 710 380 390 400 410 420 430 pF1KSD SCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL 720 730 740 750 760 770 440 450 460 470 480 490 pF1KSD TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 780 790 800 810 820 830 500 510 520 530 540 550 pF1KSD IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ 840 850 860 870 880 890 560 570 580 590 600 610 pF1KSD IFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLD 900 910 920 930 940 950 620 630 640 650 660 670 pF1KSD VYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL 960 970 980 990 1000 1010 >>XP_005262918 (OMIM: 606856,608092) PREDICTED: palladin (1400 aa) initn: 2916 init1: 2916 opt: 3046 Z-score: 1132.7 bits: 221.0 E(85289): 2.4e-56 Smith-Waterman score: 4559; 97.4% identity (97.5% similar) in 689 aa overlap (1-672:712-1400) 10 20 30 pF1KSD MSALASRSAPAMQSSGSFNYARPKQFIAAQ :::::::::::::::::::::::::::::: XP_005 PRSAPPSPPFPPPPAFPELAACTPPASPEPMSALASRSAPAMQSSGSFNYARPKQFIAAQ 690 700 710 720 730 740 40 50 60 70 80 90 pF1KSD NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP 750 760 770 780 790 800 100 110 120 130 140 150 pF1KSD PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHGQTPAAFLSALLPSQ :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_005 PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHSQTPAAFLSALLPSQ 810 820 830 840 850 860 160 170 180 190 200 210 pF1KSD PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN 870 880 890 900 910 920 220 230 240 250 pF1KSD GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQ-----------------EYKVSSC :::::::::::::::::::::::::::::::::::: ::::::: XP_005 GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQDIGSPHASVGSPLDGQKEYKVSSC 930 940 950 960 970 980 260 270 280 290 300 310 pF1KSD EQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRV 990 1000 1010 1020 1030 1040 320 330 340 350 360 370 pF1KSD AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRI 1050 1060 1070 1080 1090 1100 380 390 400 410 420 430 pF1KSD SCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL 1110 1120 1130 1140 1150 1160 440 450 460 470 480 490 pF1KSD TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 1170 1180 1190 1200 1210 1220 500 510 520 530 540 550 pF1KSD IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ 1230 1240 1250 1260 1270 1280 560 570 580 590 600 610 pF1KSD IFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLD 1290 1300 1310 1320 1330 1340 620 630 640 650 660 670 pF1KSD VYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL 1350 1360 1370 1380 1390 1400 >>XP_011530070 (OMIM: 606856,608092) PREDICTED: palladin (1468 aa) initn: 2916 init1: 2916 opt: 3046 Z-score: 1132.4 bits: 221.0 E(85289): 2.5e-56 Smith-Waterman score: 4559; 97.4% identity (97.5% similar) in 689 aa overlap (1-672:780-1468) 10 20 30 pF1KSD MSALASRSAPAMQSSGSFNYARPKQFIAAQ :::::::::::::::::::::::::::::: XP_011 PRSAPPSPPFPPPPAFPELAACTPPASPEPMSALASRSAPAMQSSGSFNYARPKQFIAAQ 750 760 770 780 790 800 40 50 60 70 80 90 pF1KSD NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPP 810 820 830 840 850 860 100 110 120 130 140 150 pF1KSD PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHGQTPAAFLSALLPSQ :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_011 PPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHSQTPAAFLSALLPSQ 870 880 890 900 910 920 160 170 180 190 200 210 pF1KSD PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN 930 940 950 960 970 980 220 230 240 250 pF1KSD GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQ-----------------EYKVSSC :::::::::::::::::::::::::::::::::::: ::::::: XP_011 GQPRLTYEERMARRLLGADSATVFNIQEPEEETANQDIGSPHASVGSPLDGQKEYKVSSC 990 1000 1010 1020 1030 1040 260 270 280 290 300 310 pF1KSD EQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRV 1050 1060 1070 1080 1090 1100 320 330 340 350 360 370 pF1KSD AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRI 1110 1120 1130 1140 1150 1160 380 390 400 410 420 430 pF1KSD SCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL 1170 1180 1190 1200 1210 1220 440 450 460 470 480 490 pF1KSD TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 1230 1240 1250 1260 1270 1280 500 510 520 530 540 550 pF1KSD IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ 1290 1300 1310 1320 1330 1340 560 570 580 590 600 610 pF1KSD IFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLD 1350 1360 1370 1380 1390 1400 620 630 640 650 660 670 pF1KSD VYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL 1410 1420 1430 1440 1450 1460 672 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:34:23 2016 done: Thu Nov 3 04:34:25 2016 Total Scan time: 14.100 Total Display time: 0.180 Function used was FASTA [36.3.4 Apr, 2011]