FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA0997, 644 aa 1>>>pF1KSDA0997 644 - 644 aa - 644 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5722+/-0.00055; mu= 13.3681+/- 0.034 mean_var=814.8333+/-228.061, 0's: 0 Z-trim(115.2): 84 B-trim: 1383 in 1/53 Lambda= 0.044930 statistics sampled from 25499 (25576) to 25499 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.3), width: 16 Scan time: 11.460 The best scores are: opt bits E(85289) NP_055765 (OMIM: 616578) zinc finger and BTB domai ( 644) 4407 302.9 2.4e-81 XP_011534870 (OMIM: 616578) PREDICTED: zinc finger ( 644) 4407 302.9 2.4e-81 NP_001116801 (OMIM: 616578) zinc finger and BTB do ( 713) 4327 297.8 9e-80 XP_011534868 (OMIM: 616578) PREDICTED: zinc finger ( 713) 4327 297.8 9e-80 XP_016876583 (OMIM: 616578) PREDICTED: zinc finger ( 713) 4327 297.8 9e-80 XP_005267467 (OMIM: 616578) PREDICTED: zinc finger ( 713) 4327 297.8 9e-80 XP_016876584 (OMIM: 616578) PREDICTED: zinc finger ( 713) 4327 297.8 9e-80 NP_003434 (OMIM: 604084) zinc finger and BTB domai ( 803) 426 45.0 0.0012 NP_001274532 (OMIM: 604084) zinc finger and BTB do ( 810) 426 45.0 0.0012 >>NP_055765 (OMIM: 616578) zinc finger and BTB domain-co (644 aa) initn: 4407 init1: 4407 opt: 4407 Z-score: 1581.4 bits: 302.9 E(85289): 2.4e-81 Smith-Waterman score: 4407; 99.8% identity (100.0% similar) in 644 aa overlap (1-644:1-644) 10 20 30 40 50 60 pF1KSD MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QLGNFPEPLFDVCKKSSVSKLSNPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: NP_055 QLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH 550 560 570 580 590 600 610 620 630 640 pF1KSD TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMASGEIGPSKPVEK :::::::::::::::::::::::::::::::::::::::::::: NP_055 TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMASGEIGPSKPVEK 610 620 630 640 >>XP_011534870 (OMIM: 616578) PREDICTED: zinc finger and (644 aa) initn: 4407 init1: 4407 opt: 4407 Z-score: 1581.4 bits: 302.9 E(85289): 2.4e-81 Smith-Waterman score: 4407; 99.8% identity (100.0% similar) in 644 aa overlap (1-644:1-644) 10 20 30 40 50 60 pF1KSD MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QLGNFPEPLFDVCKKSSVSKLSNPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_011 QLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH 550 560 570 580 590 600 610 620 630 640 pF1KSD TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMASGEIGPSKPVEK :::::::::::::::::::::::::::::::::::::::::::: XP_011 TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMASGEIGPSKPVEK 610 620 630 640 >>NP_001116801 (OMIM: 616578) zinc finger and BTB domain (713 aa) initn: 4327 init1: 4327 opt: 4327 Z-score: 1553.1 bits: 297.8 E(85289): 9e-80 Smith-Waterman score: 4327; 99.8% identity (100.0% similar) in 632 aa overlap (1-632:1-632) 10 20 30 40 50 60 pF1KSD MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QLGNFPEPLFDVCKKSSVSKLSNPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: NP_001 QLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH 550 560 570 580 590 600 610 620 630 640 pF1KSD TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMASGEIGPSKPVEK :::::::::::::::::::::::::::::::: NP_001 TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSAG 610 620 630 640 650 660 NP_001 ETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT 670 680 690 700 710 >>XP_011534868 (OMIM: 616578) PREDICTED: zinc finger and (713 aa) initn: 4327 init1: 4327 opt: 4327 Z-score: 1553.1 bits: 297.8 E(85289): 9e-80 Smith-Waterman score: 4327; 99.8% identity (100.0% similar) in 632 aa overlap (1-632:1-632) 10 20 30 40 50 60 pF1KSD MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QLGNFPEPLFDVCKKSSVSKLSNPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_011 QLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH 550 560 570 580 590 600 610 620 630 640 pF1KSD TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMASGEIGPSKPVEK :::::::::::::::::::::::::::::::: XP_011 TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSAG 610 620 630 640 650 660 XP_011 ETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT 670 680 690 700 710 >>XP_016876583 (OMIM: 616578) PREDICTED: zinc finger and (713 aa) initn: 4327 init1: 4327 opt: 4327 Z-score: 1553.1 bits: 297.8 E(85289): 9e-80 Smith-Waterman score: 4327; 99.8% identity (100.0% similar) in 632 aa overlap (1-632:1-632) 10 20 30 40 50 60 pF1KSD MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QLGNFPEPLFDVCKKSSVSKLSNPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_016 QLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH 550 560 570 580 590 600 610 620 630 640 pF1KSD TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMASGEIGPSKPVEK :::::::::::::::::::::::::::::::: XP_016 TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSAG 610 620 630 640 650 660 XP_016 ETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT 670 680 690 700 710 >>XP_005267467 (OMIM: 616578) PREDICTED: zinc finger and (713 aa) initn: 4327 init1: 4327 opt: 4327 Z-score: 1553.1 bits: 297.8 E(85289): 9e-80 Smith-Waterman score: 4327; 99.8% identity (100.0% similar) in 632 aa overlap (1-632:1-632) 10 20 30 40 50 60 pF1KSD MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QLGNFPEPLFDVCKKSSVSKLSNPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_005 QLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH 550 560 570 580 590 600 610 620 630 640 pF1KSD TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMASGEIGPSKPVEK :::::::::::::::::::::::::::::::: XP_005 TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSAG 610 620 630 640 650 660 XP_005 ETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT 670 680 690 700 710 >>XP_016876584 (OMIM: 616578) PREDICTED: zinc finger and (713 aa) initn: 4327 init1: 4327 opt: 4327 Z-score: 1553.1 bits: 297.8 E(85289): 9e-80 Smith-Waterman score: 4327; 99.8% identity (100.0% similar) in 632 aa overlap (1-632:1-632) 10 20 30 40 50 60 pF1KSD MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDAD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QLGNFPEPLFDVCKKSSVSKLSNPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_016 QLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAEN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVH 550 560 570 580 590 600 610 620 630 640 pF1KSD TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMASGEIGPSKPVEK :::::::::::::::::::::::::::::::: XP_016 TKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSAG 610 620 630 640 650 660 XP_016 ETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT 670 680 690 700 710 >>NP_003434 (OMIM: 604084) zinc finger and BTB domain-co (803 aa) initn: 571 init1: 250 opt: 426 Z-score: 186.2 bits: 45.0 E(85289): 0.0012 Smith-Waterman score: 486; 23.8% identity (51.2% similar) in 689 aa overlap (1-636:1-645) 10 20 30 40 50 60 pF1KSD MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST : :.::..::.:::.::. :.:::: ...: ..:.:::::::::: ::.:.:.. :... NP_003 MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFVD-QKDV 10 20 30 40 50 70 80 90 100 110 pF1KSD AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNV-PDC--LEDIQ ..:..:: : . .:.::: .:. .: . .. .. ..::. .. : :... NP_003 VHLDISN----AAGLGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITACHALKSLA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD DADCSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADE . : . . . ... ..: : :. :: . .: :: : .:. : NP_003 EPATSPGGNAEALATEGGDK-----RAKEEKVATS--TLSRLEQAGRSTPIGP-SRDLKE 120 130 140 150 160 180 190 200 210 220 230 pF1KSD ESLQLGNFPEPLFDVCKKSSVSKLSNPKE-RVSRRFGRSFTCDSCGFGFSCEKLLDEHVL : .. . .:... . : : . . : . . ... : :. .. . NP_003 ERGGQAQSAASGAEQTEKADAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD TCTNRHLYQNTRSYHRIVDIRDGKDSNIKAEFGE--KDSSKTFSAQTDKYRGDTSQAADD ... .. .. .. . . :. . . : :: ... . :: ::. . :.: NP_003 RKGEEEQKEQEEQEEEGAGPAEVKEEGSQLENGEAPEENENEESAGTDSGQELGSEARGL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KSD SASTTGSRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNE ..: :.: : . . . . .. . : . . : : : : :. ..:.. NP_003 RSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIHTGE-KPFSC-----RECSK 290 300 310 320 330 340 360 370 380 390 400 410 pF1KSD STDND---ELEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNS . .. . ... . :. : :: :: : : ... ...: .: NP_003 AFSDPAACKAHEKTHSPLKPYGCEE---CGKSYR--LISLLNLHKKRHSGEARYR----- 350 360 370 380 390 420 430 440 450 460 pF1KSD SPVQEDAENASCELCG-LTITEEDLSSHYLAKHIENICACGKCGQILV----KGRQLQEH :: :: : : .:. : :.. :. : ::. . : :.:. : NP_003 -----------CEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETH 400 410 420 430 440 470 480 490 500 510 pF1KSD ----AQRCGEPQ-DLTMNGLGNTEE--KMDLEENPDEQSEIRDMFVEMLDDFRDNHYQIN ..: :. : .: .:: . :. . ..: . : .:. . : : .:. NP_003 DTDKEHKC--PHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKR--HLRIH 450 460 470 480 490 520 530 540 550 pF1KSD SIQKKQLFKH-------------------SACPFRCPNCGQRFETENLVVEHMSS----- : .: . : . : .: ::. : . .. :. . NP_003 SGEKPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEK 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ---C--LDQDMFKSAIMEENERDHR--RKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVC : . . .:. . .. : : : : :..:.:.: . : .: .:: :: ..: NP_003 PYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLC 560 570 580 590 600 610 610 620 630 640 pF1KSD QTCGKQFLRERQLRLH-NDMHKGMASGEIGPSKPVEK . ::. : : .:: : . .:.: :. .: NP_003 DKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGSEVSVVTVDDMVTLATEALAATAVT 620 630 640 650 660 670 >>NP_001274532 (OMIM: 604084) zinc finger and BTB domain (810 aa) initn: 571 init1: 250 opt: 426 Z-score: 186.2 bits: 45.0 E(85289): 0.0012 Smith-Waterman score: 486; 23.8% identity (51.2% similar) in 689 aa overlap (1-636:1-645) 10 20 30 40 50 60 pF1KSD MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST : :.::..::.:::.::. :.:::: ...: ..:.:::::::::: ::.:.:.. :... NP_001 MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFVD-QKDV 10 20 30 40 50 70 80 90 100 110 pF1KSD AQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNV-PDC--LEDIQ ..:..:: : . .:.::: .:. .: . .. .. ..::. .. : :... NP_001 VHLDISN----AAGLGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITACHALKSLA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD DADCSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADE . : . . . ... ..: : :. :: . .: :: : .:. : NP_001 EPATSPGGNAEALATEGGDK-----RAKEEKVATS--TLSRLEQAGRSTPIGP-SRDLKE 120 130 140 150 160 180 190 200 210 220 230 pF1KSD ESLQLGNFPEPLFDVCKKSSVSKLSNPKE-RVSRRFGRSFTCDSCGFGFSCEKLLDEHVL : .. . .:... . : : . . : . . ... : :. .. . NP_001 ERGGQAQSAASGAEQTEKADAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD TCTNRHLYQNTRSYHRIVDIRDGKDSNIKAEFGE--KDSSKTFSAQTDKYRGDTSQAADD ... .. .. .. . . :. . . : :: ... . :: ::. . :.: NP_001 RKGEEEQKEQEEQEEEGAGPAEVKEEGSQLENGEAPEENENEESAGTDSGQELGSEARGL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KSD SASTTGSRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNE ..: :.: : . . . . .. . : . . : : : : :. ..:.. NP_001 RSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIHTGE-KPFSC-----RECSK 290 300 310 320 330 340 360 370 380 390 400 410 pF1KSD STDND---ELEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNS . .. . ... . :. : :: :: : : ... ...: .: NP_001 AFSDPAACKAHEKTHSPLKPYGCEE---CGKSYR--LISLLNLHKKRHSGEARYR----- 350 360 370 380 390 420 430 440 450 460 pF1KSD SPVQEDAENASCELCG-LTITEEDLSSHYLAKHIENICACGKCGQILV----KGRQLQEH :: :: : : .:. : :.. :. : ::. . : :.:. : NP_001 -----------CEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETH 400 410 420 430 440 470 480 490 500 510 pF1KSD ----AQRCGEPQ-DLTMNGLGNTEE--KMDLEENPDEQSEIRDMFVEMLDDFRDNHYQIN ..: :. : .: .:: . :. . ..: . : .:. . : : .:. NP_001 DTDKEHKC--PHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKR--HLRIH 450 460 470 480 490 520 530 540 550 pF1KSD SIQKKQLFKH-------------------SACPFRCPNCGQRFETENLVVEHMSS----- : .: . : . : .: ::. : . .. :. . NP_001 SGEKPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEK 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ---C--LDQDMFKSAIMEENERDHR--RKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVC : . . .:. . .. : : : : :..:.:.: . : .: .:: :: ..: NP_001 PYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLC 560 570 580 590 600 610 610 620 630 640 pF1KSD QTCGKQFLRERQLRLH-NDMHKGMASGEIGPSKPVEK . ::. : : .:: : . .:.: :. .: NP_001 DKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGSEVSVVTVDDMVTLATEALAATAVT 620 630 640 650 660 670 644 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:35:05 2016 done: Thu Nov 3 04:35:06 2016 Total Scan time: 11.460 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]