FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1020, 615 aa 1>>>pF1KSDA1020 615 - 615 aa - 615 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.8970+/-0.000425; mu= 1.6404+/- 0.026 mean_var=486.1957+/-100.866, 0's: 0 Z-trim(123.0): 1665 B-trim: 0 in 0/58 Lambda= 0.058166 statistics sampled from 39970 (42052) to 39970 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.493), width: 16 Scan time: 14.050 The best scores are: opt bits E(85289) XP_011528310 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 4248 371.4 5.1e-102 XP_011528311 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 4248 371.4 5.1e-102 XP_011528309 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 4248 371.4 5.1e-102 NP_055909 (OMIM: 607712) hypermethylated in cancer ( 615) 4248 371.4 5.1e-102 XP_011528312 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 4248 371.4 5.1e-102 XP_016884158 (OMIM: 607712) PREDICTED: hypermethyl ( 597) 4107 359.5 1.8e-98 NP_001091672 (OMIM: 603825) hypermethylated in can ( 733) 1561 146.0 4.3e-34 NP_006488 (OMIM: 603825) hypermethylated in cancer ( 714) 1560 145.9 4.5e-34 NP_001273626 (OMIM: 194552) zinc finger protein 79 ( 474) 517 58.1 7.9e-08 NP_001273625 (OMIM: 194552) zinc finger protein 79 ( 474) 517 58.1 7.9e-08 XP_006717342 (OMIM: 194552) PREDICTED: zinc finger ( 474) 517 58.1 7.9e-08 NP_001309189 (OMIM: 194552) zinc finger protein 79 ( 474) 517 58.1 7.9e-08 NP_009066 (OMIM: 194552) zinc finger protein 79 is ( 498) 517 58.2 8.1e-08 XP_005259469 (OMIM: 604749) PREDICTED: zinc finger ( 734) 511 57.9 1.4e-07 NP_004225 (OMIM: 604749) zinc finger protein 235 [ ( 738) 511 57.9 1.4e-07 NP_068735 (OMIM: 194544) zinc finger protein 70 [H ( 446) 496 56.3 2.6e-07 NP_001276331 (OMIM: 604077) zinc finger protein 13 ( 616) 498 56.7 2.8e-07 XP_016882731 (OMIM: 604077) PREDICTED: zinc finger ( 621) 498 56.7 2.8e-07 XP_016882730 (OMIM: 604077) PREDICTED: zinc finger ( 628) 498 56.7 2.8e-07 NP_001276330 (OMIM: 604077) zinc finger protein 13 ( 658) 498 56.7 2.9e-07 XP_016882729 (OMIM: 604077) PREDICTED: zinc finger ( 658) 498 56.7 2.9e-07 NP_003427 (OMIM: 604077) zinc finger protein 135 i ( 670) 498 56.8 2.9e-07 XP_005259268 (OMIM: 604077) PREDICTED: zinc finger ( 670) 498 56.8 2.9e-07 XP_006723426 (OMIM: 604077) PREDICTED: zinc finger ( 670) 498 56.8 2.9e-07 XP_006723425 (OMIM: 604077) PREDICTED: zinc finger ( 670) 498 56.8 2.9e-07 NP_009065 (OMIM: 604077) zinc finger protein 135 i ( 682) 498 56.8 2.9e-07 NP_001273627 (OMIM: 194552) zinc finger protein 79 ( 364) 488 55.5 3.6e-07 XP_016881656 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_016881650 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_016881651 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_011525949 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_011525950 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_016881654 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_005259773 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_016881647 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_016881645 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_016881648 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_016881653 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_011525952 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 NP_006622 (OMIM: 604751) zinc finger protein 266 [ ( 549) 485 55.5 5.5e-07 XP_016881652 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 NP_001258243 (OMIM: 604751) zinc finger protein 26 ( 549) 485 55.5 5.5e-07 XP_006722690 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_016881649 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_016881655 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_016881646 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_006722693 (OMIM: 604751) PREDICTED: zinc finger ( 549) 485 55.5 5.5e-07 XP_016881644 (OMIM: 604751) PREDICTED: zinc finger ( 616) 485 55.6 5.9e-07 XP_016881643 (OMIM: 604751) PREDICTED: zinc finger ( 616) 485 55.6 5.9e-07 XP_006722686 (OMIM: 604751) PREDICTED: zinc finger ( 616) 485 55.6 5.9e-07 >>XP_011528310 (OMIM: 607712) PREDICTED: hypermethylated (615 aa) initn: 4248 init1: 4248 opt: 4248 Z-score: 1952.5 bits: 371.4 E(85289): 5.1e-102 Smith-Waterman score: 4248; 99.8% identity (100.0% similar) in 615 aa overlap (1-615:1-615) 10 20 30 40 50 60 pF1KSD MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYRGLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: XP_011 TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYQGLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ 550 560 570 580 590 600 610 pF1KSD QRNLISHLRMHTSPS ::::::::::::::: XP_011 QRNLISHLRMHTSPS 610 >>XP_011528311 (OMIM: 607712) PREDICTED: hypermethylated (615 aa) initn: 4248 init1: 4248 opt: 4248 Z-score: 1952.5 bits: 371.4 E(85289): 5.1e-102 Smith-Waterman score: 4248; 99.8% identity (100.0% similar) in 615 aa overlap (1-615:1-615) 10 20 30 40 50 60 pF1KSD MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYRGLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: XP_011 TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYQGLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ 550 560 570 580 590 600 610 pF1KSD QRNLISHLRMHTSPS ::::::::::::::: XP_011 QRNLISHLRMHTSPS 610 >>XP_011528309 (OMIM: 607712) PREDICTED: hypermethylated (615 aa) initn: 4248 init1: 4248 opt: 4248 Z-score: 1952.5 bits: 371.4 E(85289): 5.1e-102 Smith-Waterman score: 4248; 99.8% identity (100.0% similar) in 615 aa overlap (1-615:1-615) 10 20 30 40 50 60 pF1KSD MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYRGLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: XP_011 TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYQGLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ 550 560 570 580 590 600 610 pF1KSD QRNLISHLRMHTSPS ::::::::::::::: XP_011 QRNLISHLRMHTSPS 610 >>NP_055909 (OMIM: 607712) hypermethylated in cancer 2 p (615 aa) initn: 4248 init1: 4248 opt: 4248 Z-score: 1952.5 bits: 371.4 E(85289): 5.1e-102 Smith-Waterman score: 4248; 99.8% identity (100.0% similar) in 615 aa overlap (1-615:1-615) 10 20 30 40 50 60 pF1KSD MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYRGLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: NP_055 TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYQGLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ 550 560 570 580 590 600 610 pF1KSD QRNLISHLRMHTSPS ::::::::::::::: NP_055 QRNLISHLRMHTSPS 610 >>XP_011528312 (OMIM: 607712) PREDICTED: hypermethylated (615 aa) initn: 4248 init1: 4248 opt: 4248 Z-score: 1952.5 bits: 371.4 E(85289): 5.1e-102 Smith-Waterman score: 4248; 99.8% identity (100.0% similar) in 615 aa overlap (1-615:1-615) 10 20 30 40 50 60 pF1KSD MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYRGLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: XP_011 TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYQGLVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ 550 560 570 580 590 600 610 pF1KSD QRNLISHLRMHTSPS ::::::::::::::: XP_011 QRNLISHLRMHTSPS 610 >>XP_016884158 (OMIM: 607712) PREDICTED: hypermethylated (597 aa) initn: 4107 init1: 4107 opt: 4107 Z-score: 1888.7 bits: 359.5 E(85289): 1.8e-98 Smith-Waterman score: 4107; 99.8% identity (100.0% similar) in 597 aa overlap (19-615:1-597) 10 20 30 40 50 60 pF1KSD MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH :::::::::::::::::::::::::::::::::::::::::: XP_016 MGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH 10 20 30 40 70 80 90 100 110 120 pF1KSD KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLL 50 60 70 80 90 100 130 140 150 160 170 180 pF1KSD TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYRGLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: XP_016 TAASYLQLPELAALCRRKLKRAGKPFGSGRAGSTGMGRPPRSQRLSTASVIQARYQGLVD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KSD GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSSTNGSSGG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KSD CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELGG 230 240 250 260 270 280 310 320 330 340 350 360 pF1KSD TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERREAGPKGP 290 300 310 320 330 340 370 380 390 400 410 420 pF1KSD CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGSEGGSGH 350 360 370 380 390 400 430 440 450 460 470 480 pF1KSD ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETG 410 420 430 440 450 460 490 500 510 520 530 540 pF1KSD SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGK 470 480 490 500 510 520 550 560 570 580 590 600 pF1KSD MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQ 530 540 550 560 570 580 610 pF1KSD QRNLISHLRMHTSPS ::::::::::::::: XP_016 QRNLISHLRMHTSPS 590 >>NP_001091672 (OMIM: 603825) hypermethylated in cancer (733 aa) initn: 1386 init1: 741 opt: 1561 Z-score: 733.1 bits: 146.0 E(85289): 4.3e-34 Smith-Waterman score: 1628; 47.8% identity (65.1% similar) in 636 aa overlap (14-611:16-613) 10 20 30 40 50 pF1KSD MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFR ::. : :: :.::.:::::::.::::::::::::.:.:..:: NP_001 MTFPEADILLKSGECAGQ-TMLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFR 10 20 30 40 50 60 70 80 90 100 110 pF1KSD AHKNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQ-------- :::::::::: :.::::.::::.::: :::: .::. .:::::::.: . . NP_001 AHKNVLAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVA 60 70 80 90 100 110 120 130 140 150 160 pF1KSD P-AEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPF-----GSGRAGSTGMGRPPRSQR : :::.....:.::::::.:.:.:::...::: :: :.: .: . .::: :. : NP_001 PGAEPSLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLR 120 130 140 150 160 170 170 180 190 200 210 220 pF1KSD LSTASVIQARYRGLVDGRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGE .: :::: : . : : : .: . . : .. . . :: NP_001 AATP-VIQACYPSPV----GPPPPPAAEPPSGPEAAV-----NTHCAELYASGPGPA--- 180 190 200 210 220 230 240 250 260 270 280 pF1KSD AGLGGCSSSTNGSSGGCEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAA :.: :.: : :::::::::: : : :.. . :: NP_001 AAL--CASERR-----CSPLCGLDLSKKSPPGSAAPERP---------LAERE--LPPRP 230 240 250 260 290 300 310 320 330 pF1KSD SAPPVANSASYSE----LGGTPDEPMD-LEGAE---DNHLSLLEAPGGQPRKSLRHSTRK ..:: :. :.:.: : . : :.. :: : : . .:: .: . NP_001 DSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLL 270 280 290 300 310 320 340 350 360 370 380 390 pF1KSD KEWGKKEPVAGSPFERREAGPKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCK .: :.:: :: . : : . :.:. : .: .. .. :. : : : :: . NP_001 YRWMKHEPGLGSYGD--ELGRERGSPSERCE---ERGGDAAVSPGGPPLGLAPPPRYPGS 330 340 350 360 370 380 400 410 420 430 440 pF1KSD EEEENGKDASEDSAQSGSEGGSGHASAHYMYRQEGY--------ETVSYGDNLYVCIPCA . .. ..: .:. : ::.. . . ::: : :.::::::::::. NP_001 LDGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCG 390 400 410 420 430 440 450 460 470 480 490 500 pF1KSD KGFPSSEQLNAHVETHTEEE--LFIKEEGAYETGSGGAEEEAE-----DLSAPSAAYTAE ::::::::::::::.:.::: :. . :.: :...:.: : : . . .: NP_001 KGFPSSEQLNAHVEAHVEEEEALYGRAEAA-EVAAGAAGLGPPFGGGGDKVAGAPGGLGE 450 460 470 480 490 500 510 520 530 540 550 560 pF1KSD P-RPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKP ::..:. :.:.:::::::::::::::::::.::.:::: ::::::::::::::::::: NP_001 LLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKP 510 520 530 540 550 560 570 580 590 600 610 pF1KSD FACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS :::: ::::::::::::::::.::::::::::.:::::.::::::::..:: NP_001 FACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAA 570 580 590 600 610 620 NP_001 GALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTHFLH 630 640 650 660 670 680 >>NP_006488 (OMIM: 603825) hypermethylated in cancer 1 p (714 aa) initn: 1386 init1: 741 opt: 1560 Z-score: 732.8 bits: 145.9 E(85289): 4.5e-34 Smith-Waterman score: 1627; 47.9% identity (65.3% similar) in 631 aa overlap (19-611:1-594) 10 20 30 40 50 60 pF1KSD MVSGPLALRWCAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAH : :: :.::.:::::::.::::::::::::.:.:..:::: NP_006 MLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAH 10 20 30 40 70 80 90 100 110 pF1KSD KNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQ--------P- :::::::: :.::::.::::.::: :::: .::. .:::::::.: . . : NP_006 KNVLAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPG 50 60 70 80 90 100 120 130 140 150 160 pF1KSD AEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPF-----GSGRAGSTGMGRPPRSQRLS :::.....:.::::::.:.:.:::...::: :: :.: .: . .::: :. : . NP_006 AEPSLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAA 110 120 130 140 150 160 170 180 190 200 210 220 pF1KSD TASVIQARYRGLVDGRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAG : :::: : . : : : .: . .. : .. . . :: :. NP_006 TP-VIQACYPSPV----GPPPPPAAEPPSGPE-----AAVNTHCAELYASGPGPA---AA 170 180 190 200 230 240 250 260 270 280 pF1KSD LGGCSSSTNGSSGGCEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASA : :.: : :::::::::: : : :.. . :: .. NP_006 L--CASERR-----CSPLCGLDLSKKSPPGSAAPERP---------LAERE--LPPRPDS 210 220 230 240 250 290 300 310 320 330 pF1KSD PPVANSASYSE----LGGTPDEPMD-LEGAE---DNHLSLLEAPGGQPRKSLRHSTRKKE :: :. :.:.: : . : :.. :: : : . .:: .: . . NP_006 PPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPDGPSLLYR 260 270 280 290 300 310 340 350 360 370 380 390 pF1KSD WGKKEPVAGSPFERREAGPKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEE : :.:: :: . : : . :.:. : .: .. .. :. : : : :: . . NP_006 WMKHEPGLGSYGD--ELGRERGSPSERCE---ERGGDAAVSPGGPPLGLAPPPRYPGSLD 320 330 340 350 360 400 410 420 430 440 450 pF1KSD EENGKDASEDSAQSGSEGGSGHASAHYMYRQEGY--------ETVSYGDNLYVCIPCAKG .. ..: .:. : ::.. . . ::: : :.::::::::::.:: NP_006 GPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKG 370 380 390 400 410 420 460 470 480 490 500 pF1KSD FPSSEQLNAHVETHTEEE--LFIKEEGAYETGSGGAEEEAE-----DLSAPSAAYTAEP- ::::::::::::.:.::: :. . :.: :...:.: : : . . .: NP_006 FPSSEQLNAHVEAHVEEEEALYGRAEAA-EVAAGAAGLGPPFGGGGDKVAGAPGGLGELL 430 440 450 460 470 480 510 520 530 540 550 560 pF1KSD RPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFA ::..:. :.:.:::::::::::::::::::.::.:::: ::::::::::::::::::::: NP_006 RPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFA 490 500 510 520 530 540 570 580 590 600 610 pF1KSD CDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS :: ::::::::::::::::.::::::::::.:::::.::::::::..:: NP_006 CDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAAGA 550 560 570 580 590 600 NP_006 LAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKAAAAELLAQTTHFLHDP 610 620 630 640 650 660 >>NP_001273626 (OMIM: 194552) zinc finger protein 79 iso (474 aa) initn: 407 init1: 407 opt: 517 Z-score: 261.6 bits: 58.1 E(85289): 7.9e-08 Smith-Waterman score: 531; 29.7% identity (55.0% similar) in 367 aa overlap (270-612:3-360) 240 250 260 270 280 290 pF1KSD GCEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELG :. :. . .:: .:. . . . : NP_001 MAAGLLTAGPRGSTFFSSVTVAFAQERWRCLV 10 20 30 300 310 320 330 340 pF1KSD GTPDEPMDLEG--AEDNHLSLLEAPGGQPRKSLRHSTRKKEW---GK--KEP------VA .:: . . :: ... : :: : .:: . . :. : :. . : .. NP_001 STPRDRFK-EGIPGKSRSLVLLGLPVSQPGMNSQLEQREGAWMLEGEDLRSPSPGWKIIS 40 50 60 70 80 90 350 360 370 380 390 pF1KSD GSPFER--REAGPKGPC----PGEEGEGVGDRVPNGILASGAGPSG--PYGEPPYPCKEE ::: :. ::. . :: ::. .:..: . : .:. : : :. . NP_001 GSPPEQALSEASFQDPCVEMPPGDSDHGTSDLEKSFNLRPVLSPQQRVPVEARPRKCETH 100 110 120 130 140 150 400 410 420 430 440 450 pF1KSD EENGKDA---SEDSAQSGSEGGSGHASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSE :. :.. . :. . . :.: . : .. :.. : : :.:.: .: NP_001 TESFKNSEILKPHRAKPYACNECGKAFS-YCSSLSQHQKSHTGEKPYECSECGKAFSQSS 160 170 180 190 200 210 460 470 480 490 500 510 pF1KSD QLNAHVETHTEEELFIKEEGAYETGSGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYK .: : . :: :. . : : : . .:. . ..:.: .:..:: :::... NP_001 SLIQHQRIHTGEKPYKCSE------CGRAFSQNANLTKHQRTHTGE-KPYRCSECEKAFS 220 230 240 250 260 520 530 540 550 560 570 pF1KSD DPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYR : ..: ::.. : .:. :. ::: : . ...: :.:.: : ::. :.::: :. NP_001 DCSALVQHQRIHTGEKPYECSDCGKAFRHSANLTNHQRTHTGEKPYKCSECGKAFSYCAA 270 280 290 300 310 320 580 590 600 610 pF1KSD LTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS . .:.:.:.:::::.: :: :.:. :: .: : :: NP_001 FIQHQRIHTGEKPYRCAACGKAFSQSANLTNHQRTHTGEKPYKCSECGKAFSQSTNLIIH 330 340 350 360 370 380 NP_001 QKTHTGEKPYKCNECGKFFSESSALIRHHIIHTGEKPYECNECGKAFNQSSSLSQHQRIH 390 400 410 420 430 440 >-- initn: 334 init1: 334 opt: 377 Z-score: 198.1 bits: 46.4 E(85289): 0.00027 Smith-Waterman score: 377; 41.3% identity (70.6% similar) in 109 aa overlap (503-611:363-471) 480 490 500 510 520 530 pF1KSD EEGAYETGSGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRP .:.::: : :.... ..: :.::: .: NP_001 GEKPYRCAACGKAFSQSANLTNHQRTHTGEKPYKCSECGKAFSQSTNLIIHQKTHTGEKP 340 350 360 370 380 390 540 550 560 570 580 590 pF1KSD FPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQ . :: :::.:.. ... :: : : ::. :.::: :... :..:.:.:.: :::::. NP_001 YKCNECGKFFSESSALIRHHIIHTGEKPYECNECGKAFNQSSSLSQHQRIHTGVKPYECS 400 410 420 430 440 450 600 610 pF1KSD LCGGKFTQQRNLISHLRMHTSPS :: : . .. : :.: NP_001 ECGKAFRCSSAFVRHQRLHAGE 460 470 >>NP_001273625 (OMIM: 194552) zinc finger protein 79 iso (474 aa) initn: 407 init1: 407 opt: 517 Z-score: 261.6 bits: 58.1 E(85289): 7.9e-08 Smith-Waterman score: 531; 29.7% identity (55.0% similar) in 367 aa overlap (270-612:3-360) 240 250 260 270 280 290 pF1KSD GCEQELGLDLSKKSPPLPPATPGPHLTPDDAAQLSDSQHGSPPAASAPPVANSASYSELG :. :. . .:: .:. . . . : NP_001 MAAGLLTAGPRGSTFFSSVTVAFAQERWRCLV 10 20 30 300 310 320 330 340 pF1KSD GTPDEPMDLEG--AEDNHLSLLEAPGGQPRKSLRHSTRKKEW---GK--KEP------VA .:: . . :: ... : :: : .:: . . :. : :. . : .. NP_001 STPRDRFK-EGIPGKSRSLVLLGLPVSQPGMNSQLEQREGAWMLEGEDLRSPSPGWKIIS 40 50 60 70 80 90 350 360 370 380 390 pF1KSD GSPFER--REAGPKGPC----PGEEGEGVGDRVPNGILASGAGPSG--PYGEPPYPCKEE ::: :. ::. . :: ::. .:..: . : .:. : : :. . NP_001 GSPPEQALSEASFQDPCVEMPPGDSDHGTSDLEKSFNLRPVLSPQQRVPVEARPRKCETH 100 110 120 130 140 150 400 410 420 430 440 450 pF1KSD EENGKDA---SEDSAQSGSEGGSGHASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSE :. :.. . :. . . :.: . : .. :.. : : :.:.: .: NP_001 TESFKNSEILKPHRAKPYACNECGKAFS-YCSSLSQHQKSHTGEKPYECSECGKAFSQSS 160 170 180 190 200 210 460 470 480 490 500 510 pF1KSD QLNAHVETHTEEELFIKEEGAYETGSGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYK .: : . :: :. . : : : . .:. . ..:.: .:..:: :::... NP_001 SLIQHQRIHTGEKPYKCSE------CGRAFSQNANLTKHQRTHTGE-KPYRCSECEKAFS 220 230 240 250 260 520 530 540 550 560 570 pF1KSD DPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYR : ..: ::.. : .:. :. ::: : . ...: :.:.: : ::. :.::: :. NP_001 DCSALVQHQRIHTGEKPYECSDCGKAFRHSANLTNHQRTHTGEKPYKCSECGKAFSYCAA 270 280 290 300 310 320 580 590 600 610 pF1KSD LTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLRMHTSPS . .:.:.:.:::::.: :: :.:. :: .: : :: NP_001 FIQHQRIHTGEKPYRCAACGKAFSQSANLTNHQRTHTGEKPYKCSECGKAFSQSTNLIIH 330 340 350 360 370 380 NP_001 QKTHTGEKPYKCNECGKFFSESSALIRHHIIHTGEKPYECNECGKAFNQSSSLSQHQRIH 390 400 410 420 430 440 >-- initn: 334 init1: 334 opt: 377 Z-score: 198.1 bits: 46.4 E(85289): 0.00027 Smith-Waterman score: 377; 41.3% identity (70.6% similar) in 109 aa overlap (503-611:363-471) 480 490 500 510 520 530 pF1KSD EEGAYETGSGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWLTRP .:.::: : :.... ..: :.::: .: NP_001 GEKPYRCAACGKAFSQSANLTNHQRTHTGEKPYKCSECGKAFSQSTNLIIHQKTHTGEKP 340 350 360 370 380 390 540 550 560 570 580 590 pF1KSD FPCNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQ . :: :::.:.. ... :: : : ::. :.::: :... :..:.:.:.: :::::. NP_001 YKCNECGKFFSESSALIRHHIIHTGEKPYECNECGKAFNQSSSLSQHQRIHTGVKPYECS 400 410 420 430 440 450 600 610 pF1KSD LCGGKFTQQRNLISHLRMHTSPS :: : . .. : :.: NP_001 ECGKAFRCSSAFVRHQRLHAGE 460 470 615 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:37:51 2016 done: Thu Nov 3 04:37:53 2016 Total Scan time: 14.050 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]