FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1028, 502 aa 1>>>pF1KSDA1028 502 - 502 aa - 502 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.0973+/-0.00108; mu= -10.9858+/- 0.064 mean_var=503.6406+/-112.661, 0's: 0 Z-trim(115.0): 230 B-trim: 0 in 0/52 Lambda= 0.057150 statistics sampled from 15289 (15530) to 15289 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.477), width: 16 Scan time: 3.690 The best scores are: opt bits E(32554) CCDS5085.1 CDK19 gene_id:23097|Hs108|chr6 ( 502) 3442 298.3 1.3e-80 CCDS75503.1 CDK19 gene_id:23097|Hs108|chr6 ( 442) 3042 265.3 9.9e-71 CCDS9317.1 CDK8 gene_id:1024|Hs108|chr13 ( 464) 2453 216.8 4.2e-56 >>CCDS5085.1 CDK19 gene_id:23097|Hs108|chr6 (502 aa) initn: 3442 init1: 3442 opt: 3442 Z-score: 1560.9 bits: 298.3 E(32554): 1.3e-80 Smith-Waterman score: 3442; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502) 10 20 30 40 50 60 pF1KSD MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS50 AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST 430 440 450 460 470 480 490 500 pF1KSD LGYSSSSQQSSQYHPSHQAHRY :::::::::::::::::::::: CCDS50 LGYSSSSQQSSQYHPSHQAHRY 490 500 >>CCDS75503.1 CDK19 gene_id:23097|Hs108|chr6 (442 aa) initn: 3042 init1: 3042 opt: 3042 Z-score: 1383.3 bits: 265.3 E(32554): 9.9e-71 Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 442 aa overlap (61-502:1-442) 40 50 60 70 80 90 pF1KSD TYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSD :::::::::::::::::::::::::::::: CCDS75 MSACREIALLRELKHPNVIALQKVFLSHSD 10 20 30 100 110 120 130 140 150 pF1KSD RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 40 50 60 70 80 90 160 170 180 190 200 210 pF1KSD DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 100 110 120 130 140 150 220 230 240 250 260 270 pF1KSD YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA 280 290 300 310 320 330 400 410 420 430 440 450 pF1KSD APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG 340 350 360 370 380 390 460 470 480 490 500 pF1KSD GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY 400 410 420 430 440 >>CCDS9317.1 CDK8 gene_id:1024|Hs108|chr13 (464 aa) initn: 2629 init1: 2400 opt: 2453 Z-score: 1120.6 bits: 216.8 E(32554): 4.2e-56 Smith-Waterman score: 2585; 77.7% identity (87.1% similar) in 502 aa overlap (1-502:1-464) 10 20 30 40 50 60 pF1KSD MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS ::::::.::..:::::::::::::::::::::::::::.::::::.:.:::::::::::: CCDS93 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP :::::::::::::::::::.::::::::.::::::::::::::::::::::::::::::: CCDS93 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF .::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH ::::::.:::::::::.:::::::::::::.::::. ::.:::::.::.: ::::::::: CCDS93 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN :::::::.: :::::::::: ::::::::.::::: :::::: ::::::::::::::::. CCDS93 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG :..:..::::..:::: :....:::: : : CCDS93 EEEPDDKGDKKNQQQQ-----------------------QGNNHTNGT-GHPG------- 370 380 430 440 450 460 470 480 pF1KSD AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST .:::: .: :: :: :. : ..::: .: ::::.:. . : . ..:: ::. CCDS93 -----NQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSS 390 400 410 420 430 440 490 500 pF1KSD LGYSSSSQQSSQYHPSHQAHRY .:::..::: :: :::.::: CCDS93 MGYSATSQQPPQY--SHQTHRY 450 460 502 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 00:16:09 2016 done: Fri Nov 4 00:16:10 2016 Total Scan time: 3.690 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]