Result of FASTA (omim) for
pF1KSDA1028
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1028, 502 aa
1>>>pF1KSDA1028 502 - 502 aa - 502 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.0405+/-0.000464; mu= -20.9340+/- 0.029
mean_var=714.3167+/-160.518, 0's: 0 Z-trim(122.9): 396 B-trim: 2641 in 1/58
Lambda= 0.047988
statistics sampled from 41185 (41719) to 41185 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.489), width: 16
Scan time: 11.610
The best scores are: opt bits E(85289)
NP_055891 (OMIM: 614720) cyclin-dependent kinase 1 ( 502) 3442 253.5 1e-66
NP_001287893 (OMIM: 614720) cyclin-dependent kinas ( 442) 3042 225.8 2.1e-58
NP_001287892 (OMIM: 614720) cyclin-dependent kinas ( 442) 3042 225.8 2.1e-58
XP_016866076 (OMIM: 614720) PREDICTED: cyclin-depe ( 442) 2989 222.1 2.6e-57
NP_001305297 (OMIM: 603184) cyclin-dependent kinas ( 463) 2465 185.8 2.3e-46
NP_001251 (OMIM: 603184) cyclin-dependent kinase 8 ( 464) 2453 185.0 4.1e-46
XP_005266928 (OMIM: 614720) PREDICTED: cyclin-depe ( 378) 2417 182.4 2e-45
XP_011533933 (OMIM: 614720) PREDICTED: cyclin-depe ( 515) 2412 182.2 3.1e-45
XP_016866077 (OMIM: 614720) PREDICTED: cyclin-depe ( 329) 2273 172.4 1.8e-42
XP_005266273 (OMIM: 603184) PREDICTED: cyclin-depe ( 404) 2078 159.0 2.4e-38
NP_001287889 (OMIM: 614720) cyclin-dependent kinas ( 458) 2004 153.9 9.1e-37
XP_011533932 (OMIM: 614720) PREDICTED: cyclin-depe ( 555) 2004 154.0 1e-36
XP_016875806 (OMIM: 603184) PREDICTED: cyclin-depe ( 338) 1646 129.0 2.2e-29
XP_011533934 (OMIM: 614720) PREDICTED: cyclin-depe ( 256) 1579 124.2 4.5e-28
XP_016875807 (OMIM: 603184) PREDICTED: cyclin-depe ( 290) 1340 107.7 4.6e-23
XP_011533167 (OMIM: 603184) PREDICTED: cyclin-depe ( 291) 1328 106.9 8.3e-23
NP_001333430 (OMIM: 603184) cyclin-dependent kinas ( 291) 1328 106.9 8.3e-23
XP_011533166 (OMIM: 603184) PREDICTED: cyclin-depe ( 291) 1328 106.9 8.3e-23
XP_011521707 (OMIM: 603464) PREDICTED: cyclin-depe ( 392) 521 51.2 6.6e-06
XP_011521709 (OMIM: 603464) PREDICTED: cyclin-depe ( 375) 514 50.7 9e-06
XP_011521710 (OMIM: 603464) PREDICTED: cyclin-depe ( 369) 493 49.2 2.4e-05
XP_011521719 (OMIM: 603464) PREDICTED: cyclin-depe ( 261) 483 48.3 3.1e-05
XP_011521708 (OMIM: 603464) PREDICTED: cyclin-depe ( 386) 485 48.7 3.7e-05
XP_016879295 (OMIM: 603464) PREDICTED: cyclin-depe ( 355) 472 47.7 6.5e-05
NP_112557 (OMIM: 603309) cyclin-dependent kinase 1 (1452) 482 49.1 0.0001
NP_003709 (OMIM: 603309) cyclin-dependent kinase 1 (1512) 482 49.1 0.00011
XP_011521717 (OMIM: 603464) PREDICTED: cyclin-depe ( 321) 455 46.5 0.00014
XP_011521715 (OMIM: 603464) PREDICTED: cyclin-depe ( 321) 455 46.5 0.00014
XP_011521713 (OMIM: 603464) PREDICTED: cyclin-depe ( 321) 455 46.5 0.00014
XP_011521718 (OMIM: 603464) PREDICTED: cyclin-depe ( 321) 455 46.5 0.00014
XP_011521714 (OMIM: 603464) PREDICTED: cyclin-depe ( 321) 455 46.5 0.00014
XP_011521712 (OMIM: 603464) PREDICTED: cyclin-depe ( 321) 455 46.5 0.00014
XP_011521716 (OMIM: 603464) PREDICTED: cyclin-depe ( 321) 455 46.5 0.00014
XP_005257515 (OMIM: 615514) PREDICTED: cyclin-depe (1256) 463 47.7 0.00024
XP_016880242 (OMIM: 615514) PREDICTED: cyclin-depe (1261) 463 47.7 0.00024
XP_016880240 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 463 47.7 0.00024
XP_016880241 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 463 47.7 0.00024
XP_016880239 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 463 47.7 0.00024
XP_011523209 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 463 47.7 0.00024
XP_011523196 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 463 47.7 0.00025
XP_011523202 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 463 47.7 0.00025
XP_011523198 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 463 47.7 0.00025
XP_011523205 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 463 47.7 0.00025
XP_016880237 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 463 47.7 0.00025
XP_011523208 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 463 47.7 0.00025
XP_011523203 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 463 47.7 0.00025
XP_011523197 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 463 47.7 0.00025
XP_011523195 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 463 47.7 0.00025
XP_011523200 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 463 47.7 0.00025
XP_016880238 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 463 47.7 0.00025
>>NP_055891 (OMIM: 614720) cyclin-dependent kinase 19 is (502 aa)
initn: 3442 init1: 3442 opt: 3442 Z-score: 1318.6 bits: 253.5 E(85289): 1e-66
Smith-Waterman score: 3442; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)
10 20 30 40 50 60
pF1KSD MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST
430 440 450 460 470 480
490 500
pF1KSD LGYSSSSQQSSQYHPSHQAHRY
::::::::::::::::::::::
NP_055 LGYSSSSQQSSQYHPSHQAHRY
490 500
>>NP_001287893 (OMIM: 614720) cyclin-dependent kinase 19 (442 aa)
initn: 3042 init1: 3042 opt: 3042 Z-score: 1169.6 bits: 225.8 E(85289): 2.1e-58
Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 442 aa overlap (61-502:1-442)
40 50 60 70 80 90
pF1KSD TYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSD
::::::::::::::::::::::::::::::
NP_001 MSACREIALLRELKHPNVIALQKVFLSHSD
10 20 30
100 110 120 130 140 150
pF1KSD RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KSD DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
100 110 120 130 140 150
220 230 240 250 260 270
pF1KSD YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KSD RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL
220 230 240 250 260 270
340 350 360 370 380 390
pF1KSD QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KSD APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG
340 350 360 370 380 390
460 470 480 490 500
pF1KSD GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
400 410 420 430 440
>>NP_001287892 (OMIM: 614720) cyclin-dependent kinase 19 (442 aa)
initn: 3042 init1: 3042 opt: 3042 Z-score: 1169.6 bits: 225.8 E(85289): 2.1e-58
Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 442 aa overlap (61-502:1-442)
40 50 60 70 80 90
pF1KSD TYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSD
::::::::::::::::::::::::::::::
NP_001 MSACREIALLRELKHPNVIALQKVFLSHSD
10 20 30
100 110 120 130 140 150
pF1KSD RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KSD DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
100 110 120 130 140 150
220 230 240 250 260 270
pF1KSD YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KSD RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL
220 230 240 250 260 270
340 350 360 370 380 390
pF1KSD QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KSD APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG
340 350 360 370 380 390
460 470 480 490 500
pF1KSD GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
400 410 420 430 440
>>XP_016866076 (OMIM: 614720) PREDICTED: cyclin-dependen (442 aa)
initn: 2989 init1: 2989 opt: 2989 Z-score: 1149.8 bits: 222.1 E(85289): 2.6e-57
Smith-Waterman score: 2989; 100.0% identity (100.0% similar) in 434 aa overlap (69-502:9-442)
40 50 60 70 80 90
pF1KSD RRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFD
::::::::::::::::::::::::::::::
XP_016 MKILKGNQLLRELKHPNVIALQKVFLSHSDRKVWLLFD
10 20 30
100 110 120 130 140 150
pF1KSD YAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANIL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KSD VMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIW
100 110 120 130 140 150
220 230 240 250 260 270
pF1KSD AIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPT
160 170 180 190 200 210
280 290 300 310 320 330
pF1KSD LQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQED
220 230 240 250 260 270
340 350 360 370 380 390
pF1KSD PLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPP
280 290 300 310 320 330
400 410 420 430 440 450
pF1KSD QQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDY
340 350 360 370 380 390
460 470 480 490 500
pF1KSD QHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
400 410 420 430 440
>>NP_001305297 (OMIM: 603184) cyclin-dependent kinase 8 (463 aa)
initn: 2609 init1: 2416 opt: 2465 Z-score: 953.5 bits: 185.8 E(85289): 2.3e-46
Smith-Waterman score: 2591; 78.1% identity (86.5% similar) in 503 aa overlap (1-502:1-463)
10 20 30 40 50 60
pF1KSD MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
::::::.::..:::::::::::::::::::::::::::.::::::.:.::::::::::::
NP_001 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
:::::::::::::::::::.::::::::.:::::::::::::::::::::::::::::::
NP_001 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
.::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
::::::.:::::::::.:::::::::::::.::::. ::.:::::.::.: :::::::::
NP_001 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
:::::::.: :::::::::: ::::::::.::::: :::::: ::::::::::::::::.
NP_001 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
310 320 330 340 350 360
370 380 390 400 410
pF1KSD EDDPEEKGDKNQQQQQ-NQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGT
:..:..:::::::::: :.: :::: : :
NP_001 EEEPDDKGDKNQQQQQGNNH-------------------------TNGT-GHPG------
370 380
420 430 440 450 460 470
pF1KSD GAGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQS
.:::: .: :: :: :. : ..::: .: ::::.:. . : . ..:: ::
NP_001 ------NQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQS
390 400 410 420 430 440
480 490 500
pF1KSD TLGYSSSSQQSSQYHPSHQAHRY
..:::..::: :: :::.:::
NP_001 SMGYSATSQQPPQY--SHQTHRY
450 460
>>NP_001251 (OMIM: 603184) cyclin-dependent kinase 8 iso (464 aa)
initn: 2629 init1: 2400 opt: 2453 Z-score: 949.0 bits: 185.0 E(85289): 4.1e-46
Smith-Waterman score: 2585; 77.7% identity (87.1% similar) in 502 aa overlap (1-502:1-464)
10 20 30 40 50 60
pF1KSD MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
::::::.::..:::::::::::::::::::::::::::.::::::.:.::::::::::::
NP_001 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
:::::::::::::::::::.::::::::.:::::::::::::::::::::::::::::::
NP_001 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
.::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
::::::.:::::::::.:::::::::::::.::::. ::.:::::.::.: :::::::::
NP_001 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
:::::::.: :::::::::: ::::::::.::::: :::::: ::::::::::::::::.
NP_001 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG
:..:..::::..:::: :....:::: : :
NP_001 EEEPDDKGDKKNQQQQ-----------------------QGNNHTNGT-GHPG-------
370 380
430 440 450 460 470 480
pF1KSD AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST
.:::: .: :: :: :. : ..::: .: ::::.:. . : . ..:: ::.
NP_001 -----NQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSS
390 400 410 420 430 440
490 500
pF1KSD LGYSSSSQQSSQYHPSHQAHRY
.:::..::: :: :::.:::
NP_001 MGYSATSQQPPQY--SHQTHRY
450 460
>>XP_005266928 (OMIM: 614720) PREDICTED: cyclin-dependen (378 aa)
initn: 2417 init1: 2417 opt: 2417 Z-score: 936.6 bits: 182.4 E(85289): 2e-45
Smith-Waterman score: 2417; 100.0% identity (100.0% similar) in 351 aa overlap (152-502:28-378)
130 140 150 160 170 180
pF1KSD QLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFN
::::::::::::::::::::::::::::::
XP_005 MDFVFNPLWKYLCLLAGKCIVLLVRPKLKPANILVMGEGPERGRVKIADMGFARLFN
10 20 30 40 50
190 200 210 220 230 240
pF1KSD SPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDI
60 70 80 90 100 110
250 260 270 280 290 300
pF1KSD KTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHK
120 130 140 150 160 170
310 320 330 340 350 360
pF1KSD VKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNE
180 190 200 210 220 230
370 380 390 400 410 420
pF1KSD DDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTGA
240 250 260 270 280 290
430 440 450 460 470 480
pF1KSD GLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTL
300 310 320 330 340 350
490 500
pF1KSD GYSSSSQQSSQYHPSHQAHRY
:::::::::::::::::::::
XP_005 GYSSSSQQSSQYHPSHQAHRY
360 370
>>XP_011533933 (OMIM: 614720) PREDICTED: cyclin-dependen (515 aa)
initn: 2556 init1: 2412 opt: 2412 Z-score: 933.1 bits: 182.2 E(85289): 3.1e-45
Smith-Waterman score: 2412; 100.0% identity (100.0% similar) in 350 aa overlap (153-502:166-515)
130 140 150 160 170 180
pF1KSD LPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNS
::::::::::::::::::::::::::::::
XP_011 LFSRRKDEKEYALKQIEGTGISMSACREIAKPANILVMGEGPERGRVKIADMGFARLFNS
140 150 160 170 180 190
190 200 210 220 230 240
pF1KSD PLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIK
200 210 220 230 240 250
250 260 270 280 290 300
pF1KSD TSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKV
260 270 280 290 300 310
310 320 330 340 350 360
pF1KSD KPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNED
320 330 340 350 360 370
370 380 390 400 410 420
pF1KSD DPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTGAG
380 390 400 410 420 430
430 440 450 460 470 480
pF1KSD LQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLG
440 450 460 470 480 490
490 500
pF1KSD YSSSSQQSSQYHPSHQAHRY
::::::::::::::::::::
XP_011 YSSSSQQSSQYHPSHQAHRY
500 510
>>XP_016866077 (OMIM: 614720) PREDICTED: cyclin-dependen (329 aa)
initn: 2273 init1: 2273 opt: 2273 Z-score: 883.4 bits: 172.4 E(85289): 1.8e-42
Smith-Waterman score: 2273; 100.0% identity (100.0% similar) in 329 aa overlap (174-502:1-329)
150 160 170 180 190 200
pF1KSD ANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPE
::::::::::::::::::::::::::::::
XP_016 MGFARLFNSPLKPLADLDPVVVTFWYRAPE
10 20 30
210 220 230 240 250 260
pF1KSD LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPA
40 50 60 70 80 90
270 280 290 300 310 320
pF1KSD DKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKR
100 110 120 130 140 150
330 340 350 360 370 380
pF1KSD ITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPT
160 170 180 190 200 210
390 400 410 420 430 440
pF1KSD APPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLG
220 230 240 250 260 270
450 460 470 480 490 500
pF1KSD PSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
280 290 300 310 320
>>XP_005266273 (OMIM: 603184) PREDICTED: cyclin-dependen (404 aa)
initn: 2254 init1: 2025 opt: 2078 Z-score: 809.4 bits: 159.0 E(85289): 2.4e-38
Smith-Waterman score: 2210; 76.0% identity (85.3% similar) in 442 aa overlap (61-502:1-404)
40 50 60 70 80 90
pF1KSD TYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSD
:::::::::::::::::::.::::::::.:
XP_005 MSACREIALLRELKHPNVISLQKVFLSHAD
10 20 30
100 110 120 130 140 150
pF1KSD RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR
::::::::::::::::::::::::::::::.::::.::::::::::::::::::::::::
XP_005 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KSD DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
100 110 120 130 140 150
220 230 240 250 260 270
pF1KSD YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI
::::::::::::::::::::::::::::::::::::.:::::::::.:::::::::::::
XP_005 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KSD RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL
.::::. ::.:::::.::.: ::::::::::::::::.: :::::::::: ::::::::.
XP_005 KKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAM
220 230 240 250 260 270
340 350 360 370 380 390
pF1KSD QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA
::::: :::::: ::::::::::::::::.:..:..::::..::::
XP_005 QDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQ--------------
280 290 300 310
400 410 420 430 440 450
pF1KSD APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG
:....:::: : : .:::: .: :: :: :. : ..::
XP_005 ---------QGNNHTNGT--------GHPG-----NQDSSHTQGPPLKKVRVVPPTTTSG
320 330 340 350
460 470 480 490 500
pF1KSD GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
: .: ::::.:. . : . ..:: ::..:::..::: :: :::.:::
XP_005 GLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQY--SHQTHRY
360 370 380 390 400
502 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:16:10 2016 done: Fri Nov 4 00:16:12 2016
Total Scan time: 11.610 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]