FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1029, 903 aa 1>>>pF1KSDA1029 903 - 903 aa - 903 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 17.0198+/-0.000498; mu= -30.7199+/- 0.031 mean_var=871.7178+/-181.062, 0's: 0 Z-trim(124.7): 87 B-trim: 0 in 0/62 Lambda= 0.043440 statistics sampled from 46805 (46916) to 46805 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.55), width: 16 Scan time: 18.220 The best scores are: opt bits E(85289) XP_005268427 (OMIM: 608155) PREDICTED: synaptopodi ( 903) 6166 402.4 5e-111 NP_009217 (OMIM: 608155) synaptopodin isoform A [H ( 903) 6166 402.4 5e-111 XP_005268428 (OMIM: 608155) PREDICTED: synaptopodi ( 903) 6166 402.4 5e-111 XP_006714818 (OMIM: 608155) PREDICTED: synaptopodi (1147) 6166 402.5 6e-111 XP_016864497 (OMIM: 608155) PREDICTED: synaptopodi (1147) 6166 402.5 6e-111 XP_016864496 (OMIM: 608155) PREDICTED: synaptopodi (1147) 6166 402.5 6e-111 NP_001103444 (OMIM: 608155) synaptopodin isoform B ( 685) 4507 298.3 8.1e-80 XP_011535854 (OMIM: 608155) PREDICTED: synaptopodi ( 929) 4507 298.5 1e-79 NP_001159680 (OMIM: 608155) synaptopodin isoform C ( 929) 4507 298.5 1e-79 NP_001159681 (OMIM: 608155) synaptopodin isoform C ( 929) 4507 298.5 1e-79 XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078) 466 45.5 0.0032 XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082) 466 45.5 0.0032 XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082) 466 45.5 0.0032 XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082) 466 45.5 0.0032 >>XP_005268427 (OMIM: 608155) PREDICTED: synaptopodin is (903 aa) initn: 6166 init1: 6166 opt: 6166 Z-score: 2114.2 bits: 402.4 E(85289): 5e-111 Smith-Waterman score: 6166; 100.0% identity (100.0% similar) in 903 aa overlap (1-903:1-903) 10 20 30 40 50 60 pF1KSD MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD PLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD RPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD PLPAPPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRGWNGSLRLKRGSLPAEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLPAPPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRGWNGSLRLKRGSLPAEAS 850 860 870 880 890 900 pF1KSD CTT ::: XP_005 CTT >>NP_009217 (OMIM: 608155) synaptopodin isoform A [Homo (903 aa) initn: 6166 init1: 6166 opt: 6166 Z-score: 2114.2 bits: 402.4 E(85289): 5e-111 Smith-Waterman score: 6166; 100.0% identity (100.0% similar) in 903 aa overlap (1-903:1-903) 10 20 30 40 50 60 pF1KSD MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD PLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 PLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD RPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 RPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD PLPAPPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRGWNGSLRLKRGSLPAEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 PLPAPPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRGWNGSLRLKRGSLPAEAS 850 860 870 880 890 900 pF1KSD CTT ::: NP_009 CTT >>XP_005268428 (OMIM: 608155) PREDICTED: synaptopodin is (903 aa) initn: 6166 init1: 6166 opt: 6166 Z-score: 2114.2 bits: 402.4 E(85289): 5e-111 Smith-Waterman score: 6166; 100.0% identity (100.0% similar) in 903 aa overlap (1-903:1-903) 10 20 30 40 50 60 pF1KSD MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD PLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD RPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD PLPAPPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRGWNGSLRLKRGSLPAEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLPAPPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRGWNGSLRLKRGSLPAEAS 850 860 870 880 890 900 pF1KSD CTT ::: XP_005 CTT >>XP_006714818 (OMIM: 608155) PREDICTED: synaptopodin is (1147 aa) initn: 6166 init1: 6166 opt: 6166 Z-score: 2112.9 bits: 402.5 E(85289): 6e-111 Smith-Waterman score: 6166; 100.0% identity (100.0% similar) in 903 aa overlap (1-903:245-1147) 10 20 30 pF1KSD MEGYSEEASLLRHLEKVASEEEEVPLVVYL :::::::::::::::::::::::::::::: XP_006 LSLSSTSLPEPGPPRHPSPQSPDRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYL 220 230 240 250 260 270 40 50 60 70 80 90 pF1KSD KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN 280 290 300 310 320 330 100 110 120 130 140 150 pF1KSD PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV 340 350 360 370 380 390 160 170 180 190 200 210 pF1KSD RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS 400 410 420 430 440 450 220 230 240 250 260 270 pF1KSD GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP 460 470 480 490 500 510 280 290 300 310 320 330 pF1KSD APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL 520 530 540 550 560 570 340 350 360 370 380 390 pF1KSD ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT 580 590 600 610 620 630 400 410 420 430 440 450 pF1KSD PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP 640 650 660 670 680 690 460 470 480 490 500 510 pF1KSD EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS 700 710 720 730 740 750 520 530 540 550 560 570 pF1KSD PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS 760 770 780 790 800 810 580 590 600 610 620 630 pF1KSD LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD 820 830 840 850 860 870 640 650 660 670 680 690 pF1KSD SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTP 880 890 900 910 920 930 700 710 720 730 740 750 pF1KSD GASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPS 940 950 960 970 980 990 760 770 780 790 800 810 pF1KSD RQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARP 1000 1010 1020 1030 1040 1050 820 830 840 850 860 870 pF1KSD GSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAK 1060 1070 1080 1090 1100 1110 880 890 900 pF1KSD SPGILGYNICPRGWNGSLRLKRGSLPAEASCTT ::::::::::::::::::::::::::::::::: XP_006 SPGILGYNICPRGWNGSLRLKRGSLPAEASCTT 1120 1130 1140 >>XP_016864497 (OMIM: 608155) PREDICTED: synaptopodin is (1147 aa) initn: 6166 init1: 6166 opt: 6166 Z-score: 2112.9 bits: 402.5 E(85289): 6e-111 Smith-Waterman score: 6166; 100.0% identity (100.0% similar) in 903 aa overlap (1-903:245-1147) 10 20 30 pF1KSD MEGYSEEASLLRHLEKVASEEEEVPLVVYL :::::::::::::::::::::::::::::: XP_016 LSLSSTSLPEPGPPRHPSPQSPDRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYL 220 230 240 250 260 270 40 50 60 70 80 90 pF1KSD KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN 280 290 300 310 320 330 100 110 120 130 140 150 pF1KSD PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV 340 350 360 370 380 390 160 170 180 190 200 210 pF1KSD RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS 400 410 420 430 440 450 220 230 240 250 260 270 pF1KSD GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP 460 470 480 490 500 510 280 290 300 310 320 330 pF1KSD APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL 520 530 540 550 560 570 340 350 360 370 380 390 pF1KSD ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT 580 590 600 610 620 630 400 410 420 430 440 450 pF1KSD PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP 640 650 660 670 680 690 460 470 480 490 500 510 pF1KSD EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS 700 710 720 730 740 750 520 530 540 550 560 570 pF1KSD PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS 760 770 780 790 800 810 580 590 600 610 620 630 pF1KSD LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD 820 830 840 850 860 870 640 650 660 670 680 690 pF1KSD SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTP 880 890 900 910 920 930 700 710 720 730 740 750 pF1KSD GASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPS 940 950 960 970 980 990 760 770 780 790 800 810 pF1KSD RQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARP 1000 1010 1020 1030 1040 1050 820 830 840 850 860 870 pF1KSD GSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAK 1060 1070 1080 1090 1100 1110 880 890 900 pF1KSD SPGILGYNICPRGWNGSLRLKRGSLPAEASCTT ::::::::::::::::::::::::::::::::: XP_016 SPGILGYNICPRGWNGSLRLKRGSLPAEASCTT 1120 1130 1140 >>XP_016864496 (OMIM: 608155) PREDICTED: synaptopodin is (1147 aa) initn: 6166 init1: 6166 opt: 6166 Z-score: 2112.9 bits: 402.5 E(85289): 6e-111 Smith-Waterman score: 6166; 100.0% identity (100.0% similar) in 903 aa overlap (1-903:245-1147) 10 20 30 pF1KSD MEGYSEEASLLRHLEKVASEEEEVPLVVYL :::::::::::::::::::::::::::::: XP_016 LSLSSTSLPEPGPPRHPSPQSPDRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYL 220 230 240 250 260 270 40 50 60 70 80 90 pF1KSD KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN 280 290 300 310 320 330 100 110 120 130 140 150 pF1KSD PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV 340 350 360 370 380 390 160 170 180 190 200 210 pF1KSD RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS 400 410 420 430 440 450 220 230 240 250 260 270 pF1KSD GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP 460 470 480 490 500 510 280 290 300 310 320 330 pF1KSD APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL 520 530 540 550 560 570 340 350 360 370 380 390 pF1KSD ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT 580 590 600 610 620 630 400 410 420 430 440 450 pF1KSD PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP 640 650 660 670 680 690 460 470 480 490 500 510 pF1KSD EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS 700 710 720 730 740 750 520 530 540 550 560 570 pF1KSD PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS 760 770 780 790 800 810 580 590 600 610 620 630 pF1KSD LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD 820 830 840 850 860 870 640 650 660 670 680 690 pF1KSD SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTP 880 890 900 910 920 930 700 710 720 730 740 750 pF1KSD GASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPS 940 950 960 970 980 990 760 770 780 790 800 810 pF1KSD RQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARP 1000 1010 1020 1030 1040 1050 820 830 840 850 860 870 pF1KSD GSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAK 1060 1070 1080 1090 1100 1110 880 890 900 pF1KSD SPGILGYNICPRGWNGSLRLKRGSLPAEASCTT ::::::::::::::::::::::::::::::::: XP_016 SPGILGYNICPRGWNGSLRLKRGSLPAEASCTT 1120 1130 1140 >>NP_001103444 (OMIM: 608155) synaptopodin isoform B [Ho (685 aa) initn: 4506 init1: 4506 opt: 4507 Z-score: 1553.9 bits: 298.3 E(85289): 8.1e-80 Smith-Waterman score: 4507; 99.3% identity (99.6% similar) in 682 aa overlap (1-682:1-682) 10 20 30 40 50 60 pF1KSD MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP :::::::::::::::: . :. NP_001 APRPSFSTRNAGIEAQVWKPSFCFK 670 680 >>XP_011535854 (OMIM: 608155) PREDICTED: synaptopodin is (929 aa) initn: 4506 init1: 4506 opt: 4507 Z-score: 1552.2 bits: 298.5 E(85289): 1e-79 Smith-Waterman score: 4507; 99.3% identity (99.6% similar) in 682 aa overlap (1-682:245-926) 10 20 30 pF1KSD MEGYSEEASLLRHLEKVASEEEEVPLVVYL :::::::::::::::::::::::::::::: XP_011 LSLSSTSLPEPGPPRHPSPQSPDRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYL 220 230 240 250 260 270 40 50 60 70 80 90 pF1KSD KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN 280 290 300 310 320 330 100 110 120 130 140 150 pF1KSD PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV 340 350 360 370 380 390 160 170 180 190 200 210 pF1KSD RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS 400 410 420 430 440 450 220 230 240 250 260 270 pF1KSD GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP 460 470 480 490 500 510 280 290 300 310 320 330 pF1KSD APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL 520 530 540 550 560 570 340 350 360 370 380 390 pF1KSD ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT 580 590 600 610 620 630 400 410 420 430 440 450 pF1KSD PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP 640 650 660 670 680 690 460 470 480 490 500 510 pF1KSD EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS 700 710 720 730 740 750 520 530 540 550 560 570 pF1KSD PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS 760 770 780 790 800 810 580 590 600 610 620 630 pF1KSD LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD 820 830 840 850 860 870 640 650 660 670 680 690 pF1KSD SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTP :::::::::::::::::::::::::::::::::::::::::::::: . :. XP_011 SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPSFCFK 880 890 900 910 920 700 710 720 730 740 750 pF1KSD GASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPS >>NP_001159680 (OMIM: 608155) synaptopodin isoform C [Ho (929 aa) initn: 4506 init1: 4506 opt: 4507 Z-score: 1552.2 bits: 298.5 E(85289): 1e-79 Smith-Waterman score: 4507; 99.3% identity (99.6% similar) in 682 aa overlap (1-682:245-926) 10 20 30 pF1KSD MEGYSEEASLLRHLEKVASEEEEVPLVVYL :::::::::::::::::::::::::::::: NP_001 LSLSSTSLPEPGPPRHPSPQSPDRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYL 220 230 240 250 260 270 40 50 60 70 80 90 pF1KSD KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN 280 290 300 310 320 330 100 110 120 130 140 150 pF1KSD PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV 340 350 360 370 380 390 160 170 180 190 200 210 pF1KSD RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS 400 410 420 430 440 450 220 230 240 250 260 270 pF1KSD GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP 460 470 480 490 500 510 280 290 300 310 320 330 pF1KSD APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL 520 530 540 550 560 570 340 350 360 370 380 390 pF1KSD ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT 580 590 600 610 620 630 400 410 420 430 440 450 pF1KSD PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP 640 650 660 670 680 690 460 470 480 490 500 510 pF1KSD EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS 700 710 720 730 740 750 520 530 540 550 560 570 pF1KSD PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS 760 770 780 790 800 810 580 590 600 610 620 630 pF1KSD LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD 820 830 840 850 860 870 640 650 660 670 680 690 pF1KSD SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTP :::::::::::::::::::::::::::::::::::::::::::::: . :. NP_001 SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPSFCFK 880 890 900 910 920 700 710 720 730 740 750 pF1KSD GASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPS >>NP_001159681 (OMIM: 608155) synaptopodin isoform C [Ho (929 aa) initn: 4506 init1: 4506 opt: 4507 Z-score: 1552.2 bits: 298.5 E(85289): 1e-79 Smith-Waterman score: 4507; 99.3% identity (99.6% similar) in 682 aa overlap (1-682:245-926) 10 20 30 pF1KSD MEGYSEEASLLRHLEKVASEEEEVPLVVYL :::::::::::::::::::::::::::::: NP_001 LSLSSTSLPEPGPPRHPSPQSPDRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYL 220 230 240 250 260 270 40 50 60 70 80 90 pF1KSD KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHN 280 290 300 310 320 330 100 110 120 130 140 150 pF1KSD PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEV 340 350 360 370 380 390 160 170 180 190 200 210 pF1KSD RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMS 400 410 420 430 440 450 220 230 240 250 260 270 pF1KSD GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP 460 470 480 490 500 510 280 290 300 310 320 330 pF1KSD APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL 520 530 540 550 560 570 340 350 360 370 380 390 pF1KSD ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT 580 590 600 610 620 630 400 410 420 430 440 450 pF1KSD PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVP 640 650 660 670 680 690 460 470 480 490 500 510 pF1KSD EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPS 700 710 720 730 740 750 520 530 540 550 560 570 pF1KSD PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS 760 770 780 790 800 810 580 590 600 610 620 630 pF1KSD LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQD 820 830 840 850 860 870 640 650 660 670 680 690 pF1KSD SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTP :::::::::::::::::::::::::::::::::::::::::::::: . :. NP_001 SLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPSFCFK 880 890 900 910 920 700 710 720 730 740 750 pF1KSD GASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPS 903 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:40:22 2016 done: Thu Nov 3 04:40:25 2016 Total Scan time: 18.220 Total Display time: 0.280 Function used was FASTA [36.3.4 Apr, 2011]