FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1034, 733 aa 1>>>pF1KSDA1034 733 - 733 aa - 733 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7418+/-0.00033; mu= 6.1652+/- 0.021 mean_var=181.7820+/-36.462, 0's: 0 Z-trim(121.5): 29 B-trim: 0 in 0/57 Lambda= 0.095126 statistics sampled from 38262 (38292) to 38262 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.449), width: 16 Scan time: 12.020 The best scores are: opt bits E(85289) XP_011509142 (OMIM: 608148,612313) PREDICTED: DNA- ( 733) 4855 678.6 2.5e-194 NP_001165988 (OMIM: 608148,612313) DNA-binding pro ( 733) 4855 678.6 2.5e-194 XP_006712435 (OMIM: 608148,612313) PREDICTED: DNA- ( 733) 4855 678.6 2.5e-194 NP_056080 (OMIM: 608148,612313) DNA-binding protei ( 733) 4855 678.6 2.5e-194 NP_001165980 (OMIM: 608148,612313) DNA-binding pro ( 733) 4855 678.6 2.5e-194 XP_005246453 (OMIM: 608148,612313) PREDICTED: DNA- ( 675) 4452 623.2 1e-177 XP_016859145 (OMIM: 608148,612313) PREDICTED: DNA- ( 675) 4452 623.2 1e-177 NP_001124482 (OMIM: 602075) DNA-binding protein SA ( 763) 2371 337.7 1.1e-91 NP_002962 (OMIM: 602075) DNA-binding protein SATB1 ( 763) 2371 337.7 1.1e-91 NP_001309803 (OMIM: 602075) DNA-binding protein SA ( 763) 2371 337.7 1.1e-91 NP_001309804 (OMIM: 602075) DNA-binding protein SA ( 763) 2371 337.7 1.1e-91 NP_001309801 (OMIM: 602075) DNA-binding protein SA ( 763) 2371 337.7 1.1e-91 NP_001309802 (OMIM: 602075) DNA-binding protein SA ( 763) 2371 337.7 1.1e-91 NP_001309805 (OMIM: 602075) DNA-binding protein SA ( 691) 2350 334.8 7.3e-91 NP_001182399 (OMIM: 602075) DNA-binding protein SA ( 795) 2312 329.6 3e-89 XP_011532291 (OMIM: 602075) PREDICTED: DNA-binding ( 795) 2312 329.6 3e-89 NP_001309800 (OMIM: 602075) DNA-binding protein SA ( 795) 2312 329.6 3e-89 XP_011532290 (OMIM: 602075) PREDICTED: DNA-binding ( 795) 2312 329.6 3e-89 XP_011532292 (OMIM: 602075) PREDICTED: DNA-binding ( 534) 1962 281.4 6.3e-75 >>XP_011509142 (OMIM: 608148,612313) PREDICTED: DNA-bind (733 aa) initn: 4855 init1: 4855 opt: 4855 Z-score: 3609.8 bits: 678.6 E(85289): 2.5e-194 Smith-Waterman score: 4855; 100.0% identity (100.0% similar) in 733 aa overlap (1-733:1-733) 10 20 30 40 50 60 pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA 670 680 690 700 710 720 730 pF1KSD DKSKAAPAEIDQR ::::::::::::: XP_011 DKSKAAPAEIDQR 730 >>NP_001165988 (OMIM: 608148,612313) DNA-binding protein (733 aa) initn: 4855 init1: 4855 opt: 4855 Z-score: 3609.8 bits: 678.6 E(85289): 2.5e-194 Smith-Waterman score: 4855; 100.0% identity (100.0% similar) in 733 aa overlap (1-733:1-733) 10 20 30 40 50 60 pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA 670 680 690 700 710 720 730 pF1KSD DKSKAAPAEIDQR ::::::::::::: NP_001 DKSKAAPAEIDQR 730 >>XP_006712435 (OMIM: 608148,612313) PREDICTED: DNA-bind (733 aa) initn: 4855 init1: 4855 opt: 4855 Z-score: 3609.8 bits: 678.6 E(85289): 2.5e-194 Smith-Waterman score: 4855; 100.0% identity (100.0% similar) in 733 aa overlap (1-733:1-733) 10 20 30 40 50 60 pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA 670 680 690 700 710 720 730 pF1KSD DKSKAAPAEIDQR ::::::::::::: XP_006 DKSKAAPAEIDQR 730 >>NP_056080 (OMIM: 608148,612313) DNA-binding protein SA (733 aa) initn: 4855 init1: 4855 opt: 4855 Z-score: 3609.8 bits: 678.6 E(85289): 2.5e-194 Smith-Waterman score: 4855; 100.0% identity (100.0% similar) in 733 aa overlap (1-733:1-733) 10 20 30 40 50 60 pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA 670 680 690 700 710 720 730 pF1KSD DKSKAAPAEIDQR ::::::::::::: NP_056 DKSKAAPAEIDQR 730 >>NP_001165980 (OMIM: 608148,612313) DNA-binding protein (733 aa) initn: 4855 init1: 4855 opt: 4855 Z-score: 3609.8 bits: 678.6 E(85289): 2.5e-194 Smith-Waterman score: 4855; 100.0% identity (100.0% similar) in 733 aa overlap (1-733:1-733) 10 20 30 40 50 60 pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVGGLMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLALGYSHSSAAQAQGIIKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLEDLPAEQWNHATVRNALK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGRWYKKYKKIKVERVERE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPHSQIHHSTPIRNQVPALQPIMSPGLLSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLNHPPIPRAVKPEPTNSSVEV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEILRKEEDPRTASQSLLVNLRAMQN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSSSRTPQAKTSTPTTDLPIKVDGAN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWLCELLRWKENPSPENRTLWENLCT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRRFLNLPQHERDVIYEEESRHHHSERMQHVVQLPPEPVQVLHRQQSQPAKESSPPREEA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPPPPPTEDSCAKKPRSRTKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTII 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFFQNQRYHVKHHGKLKEHLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENA 670 680 690 700 710 720 730 pF1KSD DKSKAAPAEIDQR ::::::::::::: NP_001 DKSKAAPAEIDQR 730 >>XP_005246453 (OMIM: 608148,612313) PREDICTED: DNA-bind (675 aa) initn: 4452 init1: 4452 opt: 4452 Z-score: 3311.5 bits: 623.2 E(85289): 1e-177 Smith-Waterman score: 4452; 100.0% identity (100.0% similar) in 675 aa overlap (59-733:1-675) 30 40 50 60 70 80 pF1KSD VKVARLEQNGSPMGARGRPNGAVAKAVGGLMIPVFCVVEQLDGSLEYDNREEHAEFVLVR :::::::::::::::::::::::::::::: XP_005 MIPVFCVVEQLDGSLEYDNREEHAEFVLVR 10 20 30 90 100 110 120 130 140 pF1KSD KDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYH 40 50 60 70 80 90 150 160 170 180 190 200 pF1KSD VVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNS 100 110 120 130 140 150 210 220 230 240 250 260 pF1KSD TYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTN 160 170 180 190 200 210 270 280 290 300 310 320 pF1KSD EQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLA 220 230 240 250 260 270 330 340 350 360 370 380 pF1KSD HQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFN 280 290 300 310 320 330 390 400 410 420 430 440 pF1KSD RTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMV 340 350 360 370 380 390 450 460 470 480 490 500 pF1KSD SSASSSPSSSRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSASSSPSSSRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKV 400 410 420 430 440 450 510 520 530 540 550 560 pF1KSD AANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERM 460 470 480 490 500 510 570 580 590 600 610 620 pF1KSD QHVVQLPPEPVQVLHRQQSQPAKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QHVVQLPPEPVQVLHRQQSQPAKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGI 520 530 540 550 560 570 630 640 650 660 670 680 pF1KSD LQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAE 580 590 600 610 620 630 690 700 710 720 730 pF1KSD YKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR ::::::::::::::::::::::::::::::::::::::::::::: XP_005 YKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR 640 650 660 670 >>XP_016859145 (OMIM: 608148,612313) PREDICTED: DNA-bind (675 aa) initn: 4452 init1: 4452 opt: 4452 Z-score: 3311.5 bits: 623.2 E(85289): 1e-177 Smith-Waterman score: 4452; 100.0% identity (100.0% similar) in 675 aa overlap (59-733:1-675) 30 40 50 60 70 80 pF1KSD VKVARLEQNGSPMGARGRPNGAVAKAVGGLMIPVFCVVEQLDGSLEYDNREEHAEFVLVR :::::::::::::::::::::::::::::: XP_016 MIPVFCVVEQLDGSLEYDNREEHAEFVLVR 10 20 30 90 100 110 120 130 140 pF1KSD KDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDVLFSQLVETALLALGYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYH 40 50 60 70 80 90 150 160 170 180 190 200 pF1KSD VVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVTLKIQLQSCSKLEDLPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNS 100 110 120 130 140 150 210 220 230 240 250 260 pF1KSD TYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYYANVSATKCQEFGRWYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTN 160 170 180 190 200 210 270 280 290 300 310 320 pF1KSD EQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQSPHSQIHHSTPIRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLA 220 230 240 250 260 270 330 340 350 360 370 380 pF1KSD HQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HQHPQAINQQFLNHPPIPRAVKPEPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFN 280 290 300 310 320 330 390 400 410 420 430 440 pF1KSD RTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RTQGLLSEILRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMV 340 350 360 370 380 390 450 460 470 480 490 500 pF1KSD SSASSSPSSSRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSASSSPSSSRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKV 400 410 420 430 440 450 510 520 530 540 550 560 pF1KSD AANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AANKSQGWLCELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESRHHHSERM 460 470 480 490 500 510 570 580 590 600 610 620 pF1KSD QHVVQLPPEPVQVLHRQQSQPAKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHVVQLPPEPVQVLHRQQSQPAKESSPPREEAPPPPPPTEDSCAKKPRSRTKISLEALGI 520 530 540 550 560 570 630 640 650 660 670 680 pF1KSD LQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKEHLGSAVDVAE 580 590 600 610 620 630 690 700 710 720 730 pF1KSD YKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR ::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR 640 650 660 670 >>NP_001124482 (OMIM: 602075) DNA-binding protein SATB1 (763 aa) initn: 2339 init1: 1042 opt: 2371 Z-score: 1767.2 bits: 337.7 E(85289): 1.1e-91 Smith-Waterman score: 2873; 62.1% identity (80.4% similar) in 760 aa overlap (1-718:1-748) 10 20 30 40 50 pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVG---- :.. .:. .. . .. : :::: .:.:::::::::.: ::: ... :: : NP_001 MDHLNEATQGKEHSEMSNNVSDPKGPP-AKIARLEQNGSPLG-RGRLGSTGAKMQGVPLK 10 20 30 40 50 60 70 80 90 100 pF1KSD ------------GLMIPVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLAL : :.:::::::. ....::: .::::::::::::.::.::.: :::.: NP_001 HSGHLMKTNLRKGTMLPVFCVVEHYENAIEYDCKEEHAEFVLVRKDMLFNQLIEMALLSL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD GYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLED ::::::::::.:.:..:.:::.::::::::::::::::::::::::::::::.:: :::: NP_001 GYSHSSAAQAKGLIQVGKWNPVPLSYVTDAPDATVADMLQDVYHVVTLKIQLHSCPKLED 120 130 140 150 160 170 170 180 190 200 210 220 pF1KSD LPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGR :: :::.:.:::::::.:::.::::.::::::::::::::::::::::::::.::::::: NP_001 LPPEQWSHTTVRNALKDLLKDMNQSSLAKECPLSQSMISSIVNSTYYANVSAAKCQEFGR 180 190 200 210 220 230 230 240 250 260 270 280 pF1KSD WYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPH-SQIHH-STP- :::..:: : :: ..::. :.:. . :..: :.: :: : .:. : : : NP_001 WYKHFKKTKDMMVEMDSLSE---LSQQGANHVNFGQQPVPGNTAEQPPSPAQLSHGSQPS 240 250 260 270 280 290 290 300 310 320 330 340 pF1KSD IRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLN .:. .: :.: ::.: .::::: ::..::.:.::: ::.::::.: ..:::.:: NP_001 VRTPLPNLHP----GLVSTPISPQLVNQQLVMAQLLNQQYAVNRLLAQQ---SLNQQYLN 300 310 320 330 340 350 360 370 380 390 pF1KSD HPP-IPRAV-KP--EPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEI ::: . :.. :: . .....::: .::: ::::::::..:::::::::::::::::::: NP_001 HPPPVSRSMNKPLEQQVSTNTEVSSEIYQWVRDELKRAGISQAVFARVAFNRTQGLLSEI 350 360 370 380 390 400 400 410 420 430 440 450 pF1KSD LRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSS :::::::.:::::::::::::::::.:::.:::::::::::::.: .: . : NP_001 LRKEEDPKTASQSLLVNLRAMQNFLQLPEAERDRIYQDERERSLNAASAMGPAPLISTPP 410 420 430 440 450 460 460 470 480 490 500 510 pF1KSD SRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWL :: ::.::.: .:. : .. ..::.:.::::::::::::::::::::::::.:::::: NP_001 SRPPQVKTATIATERNGKPENNTMNINASIYDEIQQEMKRAKVSQALFAKVAATKSQGWL 470 480 490 500 510 520 520 530 540 550 560 570 pF1KSD CELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESR--HHHSERMQHVVQLP ::::::::.:::::::::::: :::::.::: :::.:::.:: :::..: :....: NP_001 CELLRWKEDPSPENRTLWENLSMIRRFLSLPQPERDAIYEQESNAVHHHGDRPPHIIHVP 530 540 550 560 570 580 580 590 600 610 pF1KSD PEPVQVLHRQQSQPAKESS---PPREEAPP---P--PP--PTEDSCA-------KKPRSR : .: ..::.: .... ::. . : : :: :: : : .: : : NP_001 AEQIQQQQQQQQQQQQQQQAPPPPQPQQQPQTGPRLPPRQPTVASPAESDEENRQKTRPR 590 600 610 620 630 640 620 630 640 650 660 670 pF1KSD TKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKE ::::.::::::::::.:::::::.:::.::::::::::.:::::::::::..:::::::. NP_001 TKISVEALGILQSFIQDVGLYPDEEAIQTLSAQLDLPKYTIIKFFQNQRYYLKHHGKLKD 650 660 670 680 690 700 680 690 700 710 720 730 pF1KSD HLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR . : :::::::.:::: . ::. ...... ...:. ::: NP_001 NSGLEVDVAEYKEEELLKDLEESVQDKNTNTLFSVKLEEELSVEGNTDINTDLKD 710 720 730 740 750 760 >>NP_002962 (OMIM: 602075) DNA-binding protein SATB1 iso (763 aa) initn: 2339 init1: 1042 opt: 2371 Z-score: 1767.2 bits: 337.7 E(85289): 1.1e-91 Smith-Waterman score: 2873; 62.1% identity (80.4% similar) in 760 aa overlap (1-718:1-748) 10 20 30 40 50 pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVG---- :.. .:. .. . .. : :::: .:.:::::::::.: ::: ... :: : NP_002 MDHLNEATQGKEHSEMSNNVSDPKGPP-AKIARLEQNGSPLG-RGRLGSTGAKMQGVPLK 10 20 30 40 50 60 70 80 90 100 pF1KSD ------------GLMIPVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLAL : :.:::::::. ....::: .::::::::::::.::.::.: :::.: NP_002 HSGHLMKTNLRKGTMLPVFCVVEHYENAIEYDCKEEHAEFVLVRKDMLFNQLIEMALLSL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD GYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLED ::::::::::.:.:..:.:::.::::::::::::::::::::::::::::::.:: :::: NP_002 GYSHSSAAQAKGLIQVGKWNPVPLSYVTDAPDATVADMLQDVYHVVTLKIQLHSCPKLED 120 130 140 150 160 170 170 180 190 200 210 220 pF1KSD LPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGR :: :::.:.:::::::.:::.::::.::::::::::::::::::::::::::.::::::: NP_002 LPPEQWSHTTVRNALKDLLKDMNQSSLAKECPLSQSMISSIVNSTYYANVSAAKCQEFGR 180 190 200 210 220 230 230 240 250 260 270 280 pF1KSD WYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPH-SQIHH-STP- :::..:: : :: ..::. :.:. . :..: :.: :: : .:. : : : NP_002 WYKHFKKTKDMMVEMDSLSE---LSQQGANHVNFGQQPVPGNTAEQPPSPAQLSHGSQPS 240 250 260 270 280 290 290 300 310 320 330 340 pF1KSD IRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLN .:. .: :.: ::.: .::::: ::..::.:.::: ::.::::.: ..:::.:: NP_002 VRTPLPNLHP----GLVSTPISPQLVNQQLVMAQLLNQQYAVNRLLAQQ---SLNQQYLN 300 310 320 330 340 350 360 370 380 390 pF1KSD HPP-IPRAV-KP--EPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEI ::: . :.. :: . .....::: .::: ::::::::..:::::::::::::::::::: NP_002 HPPPVSRSMNKPLEQQVSTNTEVSSEIYQWVRDELKRAGISQAVFARVAFNRTQGLLSEI 350 360 370 380 390 400 400 410 420 430 440 450 pF1KSD LRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSS :::::::.:::::::::::::::::.:::.:::::::::::::.: .: . : NP_002 LRKEEDPKTASQSLLVNLRAMQNFLQLPEAERDRIYQDERERSLNAASAMGPAPLISTPP 410 420 430 440 450 460 460 470 480 490 500 510 pF1KSD SRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWL :: ::.::.: .:. : .. ..::.:.::::::::::::::::::::::::.:::::: NP_002 SRPPQVKTATIATERNGKPENNTMNINASIYDEIQQEMKRAKVSQALFAKVAATKSQGWL 470 480 490 500 510 520 520 530 540 550 560 570 pF1KSD CELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESR--HHHSERMQHVVQLP ::::::::.:::::::::::: :::::.::: :::.:::.:: :::..: :....: NP_002 CELLRWKEDPSPENRTLWENLSMIRRFLSLPQPERDAIYEQESNAVHHHGDRPPHIIHVP 530 540 550 560 570 580 580 590 600 610 pF1KSD PEPVQVLHRQQSQPAKESS---PPREEAPP---P--PP--PTEDSCA-------KKPRSR : .: ..::.: .... ::. . : : :: :: : : .: : : NP_002 AEQIQQQQQQQQQQQQQQQAPPPPQPQQQPQTGPRLPPRQPTVASPAESDEENRQKTRPR 590 600 610 620 630 640 620 630 640 650 660 670 pF1KSD TKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKE ::::.::::::::::.:::::::.:::.::::::::::.:::::::::::..:::::::. NP_002 TKISVEALGILQSFIQDVGLYPDEEAIQTLSAQLDLPKYTIIKFFQNQRYYLKHHGKLKD 650 660 670 680 690 700 680 690 700 710 720 730 pF1KSD HLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR . : :::::::.:::: . ::. ...... ...:. ::: NP_002 NSGLEVDVAEYKEEELLKDLEESVQDKNTNTLFSVKLEEELSVEGNTDINTDLKD 710 720 730 740 750 760 >>NP_001309803 (OMIM: 602075) DNA-binding protein SATB1 (763 aa) initn: 2339 init1: 1042 opt: 2371 Z-score: 1767.2 bits: 337.7 E(85289): 1.1e-91 Smith-Waterman score: 2873; 62.1% identity (80.4% similar) in 760 aa overlap (1-718:1-748) 10 20 30 40 50 pF1KSD MERRSESPCLRDSPDRRSGSPDVKGPPPVKVARLEQNGSPMGARGRPNGAVAKAVG---- :.. .:. .. . .. : :::: .:.:::::::::.: ::: ... :: : NP_001 MDHLNEATQGKEHSEMSNNVSDPKGPP-AKIARLEQNGSPLG-RGRLGSTGAKMQGVPLK 10 20 30 40 50 60 70 80 90 100 pF1KSD ------------GLMIPVFCVVEQLDGSLEYDNREEHAEFVLVRKDVLFSQLVETALLAL : :.:::::::. ....::: .::::::::::::.::.::.: :::.: NP_001 HSGHLMKTNLRKGTMLPVFCVVEHYENAIEYDCKEEHAEFVLVRKDMLFNQLIEMALLSL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KSD GYSHSSAAQAQGIIKLGRWNPLPLSYVTDAPDATVADMLQDVYHVVTLKIQLQSCSKLED ::::::::::.:.:..:.:::.::::::::::::::::::::::::::::::.:: :::: NP_001 GYSHSSAAQAKGLIQVGKWNPVPLSYVTDAPDATVADMLQDVYHVVTLKIQLHSCPKLED 120 130 140 150 160 170 170 180 190 200 210 220 pF1KSD LPAEQWNHATVRNALKELLKEMNQSTLAKECPLSQSMISSIVNSTYYANVSATKCQEFGR :: :::.:.:::::::.:::.::::.::::::::::::::::::::::::::.::::::: NP_001 LPPEQWSHTTVRNALKDLLKDMNQSSLAKECPLSQSMISSIVNSTYYANVSAAKCQEFGR 180 190 200 210 220 230 230 240 250 260 270 280 pF1KSD WYKKYKKIKVERVERENLSDYCVLGQRPMHLPNMNQLASLGKTNEQSPH-SQIHH-STP- :::..:: : :: ..::. :.:. . :..: :.: :: : .:. : : : NP_001 WYKHFKKTKDMMVEMDSLSE---LSQQGANHVNFGQQPVPGNTAEQPPSPAQLSHGSQPS 240 250 260 270 280 290 290 300 310 320 330 340 pF1KSD IRNQVPALQPIMSPGLLSPQLSPQLVRQQIAMAHLINQQIAVSRLLAHQHPQAINQQFLN .:. .: :.: ::.: .::::: ::..::.:.::: ::.::::.: ..:::.:: NP_001 VRTPLPNLHP----GLVSTPISPQLVNQQLVMAQLLNQQYAVNRLLAQQ---SLNQQYLN 300 310 320 330 340 350 360 370 380 390 pF1KSD HPP-IPRAV-KP--EPTNSSVEVSPDIYQQVRDELKRASVSQAVFARVAFNRTQGLLSEI ::: . :.. :: . .....::: .::: ::::::::..:::::::::::::::::::: NP_001 HPPPVSRSMNKPLEQQVSTNTEVSSEIYQWVRDELKRAGISQAVFARVAFNRTQGLLSEI 350 360 370 380 390 400 400 410 420 430 440 450 pF1KSD LRKEEDPRTASQSLLVNLRAMQNFLNLPEVERDRIYQDERERSMNPNVSMVSSASSSPSS :::::::.:::::::::::::::::.:::.:::::::::::::.: .: . : NP_001 LRKEEDPKTASQSLLVNLRAMQNFLQLPEAERDRIYQDERERSLNAASAMGPAPLISTPP 410 420 430 440 450 460 460 470 480 490 500 510 pF1KSD SRTPQAKTSTPTTDLPIKVDGANINITAAIYDEIQQEMKRAKVSQALFAKVAANKSQGWL :: ::.::.: .:. : .. ..::.:.::::::::::::::::::::::::.:::::: NP_001 SRPPQVKTATIATERNGKPENNTMNINASIYDEIQQEMKRAKVSQALFAKVAATKSQGWL 470 480 490 500 510 520 520 530 540 550 560 570 pF1KSD CELLRWKENPSPENRTLWENLCTIRRFLNLPQHERDVIYEEESR--HHHSERMQHVVQLP ::::::::.:::::::::::: :::::.::: :::.:::.:: :::..: :....: NP_001 CELLRWKEDPSPENRTLWENLSMIRRFLSLPQPERDAIYEQESNAVHHHGDRPPHIIHVP 530 540 550 560 570 580 580 590 600 610 pF1KSD PEPVQVLHRQQSQPAKESS---PPREEAPP---P--PP--PTEDSCA-------KKPRSR : .: ..::.: .... ::. . : : :: :: : : .: : : NP_001 AEQIQQQQQQQQQQQQQQQAPPPPQPQQQPQTGPRLPPRQPTVASPAESDEENRQKTRPR 590 600 610 620 630 640 620 630 640 650 660 670 pF1KSD TKISLEALGILQSFIHDVGLYPDQEAIHTLSAQLDLPKHTIIKFFQNQRYHVKHHGKLKE ::::.::::::::::.:::::::.:::.::::::::::.:::::::::::..:::::::. NP_001 TKISVEALGILQSFIQDVGLYPDEEAIQTLSAQLDLPKYTIIKFFQNQRYYLKHHGKLKD 650 660 670 680 690 700 680 690 700 710 720 730 pF1KSD HLGSAVDVAEYKDEELLTESEENDSEEGSEEMYKVEAEEENADKSKAAPAEIDQR . : :::::::.:::: . ::. ...... ...:. ::: NP_001 NSGLEVDVAEYKEEELLKDLEESVQDKNTNTLFSVKLEEELSVEGNTDINTDLKD 710 720 730 740 750 760 733 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:41:09 2016 done: Thu Nov 3 04:41:11 2016 Total Scan time: 12.020 Total Display time: 0.220 Function used was FASTA [36.3.4 Apr, 2011]