FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1048, 863 aa
1>>>pF1KSDA1048 863 - 863 aa - 863 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.9102+/-0.00128; mu= -24.2044+/- 0.077
mean_var=753.0222+/-161.394, 0's: 0 Z-trim(115.7): 72 B-trim: 0 in 0/54
Lambda= 0.046738
statistics sampled from 16210 (16267) to 16210 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.5), width: 16
Scan time: 4.670
The best scores are: opt bits E(32554)
CCDS1893.2 AAK1 gene_id:22848|Hs108|chr2 ( 961) 5554 390.3 9e-108
CCDS34019.1 BMP2K gene_id:55589|Hs108|chr4 ( 662) 2144 160.2 1.1e-38
CCDS47083.1 BMP2K gene_id:55589|Hs108|chr4 (1161) 2149 160.7 1.3e-38
>>CCDS1893.2 AAK1 gene_id:22848|Hs108|chr2 (961 aa)
initn: 5772 init1: 5554 opt: 5554 Z-score: 2048.4 bits: 390.3 E(32554): 9e-108
Smith-Waterman score: 5554; 98.9% identity (99.6% similar) in 833 aa overlap (1-833:1-833)
10 20 30 40 50 60
pF1KSD MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 FLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 EVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 NILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIIT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 TKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD RPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 RPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD ETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 ETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD QAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 QAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQ
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
CCDS18 AQQQPAGTFYQQQQAQTQQFQAVHPATQKPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD QQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 QQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 PKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFSKLTAEELLNKDFAKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 AEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFSKLTAEELLNKDFAKLG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD EGKHPEKLGGSAESLIPGFQSTQGDAFATTSFSAGTAEKRKGGQTVDSGLPLLSVSDPFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS18 EGKHPEKLGGSAESLIPGFQSTQGDAFATTSFSAGTAEKRKGGQTVDSGLPLLSVSDPFI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIGKVIISVSSVMHDMCACF
:::::::::::::::::::::::::::::::::::::::::: :. ..: :..
CCDS18 PLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIEKADVAVESLIPGLEPPV
790 800 810 820 830 840
850 860
pF1KSD KNDKYLVNQSLGNSPATPEAKAI
CCDS18 PQRLPSQTESVTSNRTDSLTGEDSLLDCSLLSNPTTDLLEEFAPTAISAPVHKAAEDSNL
850 860 870 880 890 900
>>CCDS34019.1 BMP2K gene_id:55589|Hs108|chr4 (662 aa)
initn: 1743 init1: 1535 opt: 2144 Z-score: 807.9 bits: 160.2 E(32554): 1.1e-38
Smith-Waterman score: 2264; 52.7% identity (69.7% similar) in 732 aa overlap (1-723:1-652)
10 20 30 40 50
pF1KSD MKKFFDSRREQGGSGLGS--GSSGGGGSTSGLGSG--YIG-RVFGIGRQQVTVDEVLAEG
:::: . .:::: :. :..::.:. .: ::: .: :::..::.:::..: ::::
CCDS34 MKKFSRMPKSEGGSGGGAAGGGAGGAGAGAGCGSGGSSVGVRVFAVGRHQVTLEESLAEG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD GFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVS
::. :::::: .:..::::::.::: ::.:::::: ::..::::::::::.: ..:..:
CCDS34 GFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSIS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD SGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHR
. .::::::::..::.::::: ::..::::::: ::::::::::::::::::::::::::
CCDS34 D-NVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHR
130 140 150 160 170
180 190 200 210 220 230
pF1KSD DLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYS
:::::::::.: :.::::::::::::: ::: .:::.::.:::::::::::::::.:::.
CCDS34 DLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD GKIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLE
:: ::::::::::::::::::.::::::::::::::::::::::::::...:::::.:::
CCDS34 GKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD PDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTD
:::..::::.:::::.::. ::.::. :..:: ::. ::::. ::::::.:.: :::.::
CCDS34 PDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIPSALPEPMTASEAAARKSQIKARITD
300 310 320 330 340 350
360 370 380 390 400 410
pF1KSD PIPTTETSIAPRQRPKAGQ-TQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLAS
: :::::::::::::.. : .:..: :: . :: : . : :. : :
CCDS34 TIGPTETSIAPRQRPKANSATTATPSVLTIQSSATPVKVLA----PGEFGNHRPKGALRP
360 370 380 390 400 410
420 430 440 450 460 470
pF1KSD VPQPK---PQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQ
:. :.::.:: :: . :: . . . . : :::: .:
CCDS34 GNGPEILLGQGPPQQP--------PQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQ---QQ
420 430 440 450 460
480 490 500 510 520 530
pF1KSD QQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNF
:::::: ::: :::: : :: . : ...:.:.
CCDS34 QQQQQQQQQQQQQ------QQQQQQQQQHHHHH-------------------HHHLLQDA
470 480 490
540 550 560 570 580 590
pF1KSD YQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEP
:.:: :. ::::. :::. : . ::::. . : : .
CCDS34 YMQQYQHATQQQQM-----------------LQQQFLMHSVYQPQPSASQYPTMMPQYQ-
500 510 520 530 540
600 610 620 630 640 650
pF1KSD AIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASK
:: .:: .: : .:. .: .::. .: . : . ..::.
CCDS34 --QAFFQQQMLAQHQP-----SQQQASPEYLTSPQE--------FSPALVSYTSSLPAQV
550 560 570 580
660 670 680 690 700 710
pF1KSD STQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFSKLTAEEL
.: . ..: . ..:.. . . :.:.:. :: . : :::: .::::::: :::
CCDS34 GTIM------DSSYSANRSVADKEAIANFTNQKNISNPPDMSGWNPFGEDNFSKLTEEEL
590 600 610 620 630 640
720 730 740 750 760 770
pF1KSD LNKDFAKLGEGKHPEKLGGSAESLIPGFQSTQGDAFATTSFSAGTAEKRKGGQTVDSGLP
:...: : .:
CCDS34 LDREFDLLRSSKGHLKAYFASQ
650 660
>>CCDS47083.1 BMP2K gene_id:55589|Hs108|chr4 (1161 aa)
initn: 1743 init1: 1535 opt: 2149 Z-score: 806.4 bits: 160.7 E(32554): 1.3e-38
Smith-Waterman score: 2286; 50.5% identity (68.7% similar) in 780 aa overlap (1-767:1-700)
10 20 30 40 50
pF1KSD MKKFFDSRREQGGSGLGS--GSSGGGGSTSGLGSG--YIG-RVFGIGRQQVTVDEVLAEG
:::: . .:::: :. :..::.:. .: ::: .: :::..::.:::..: ::::
CCDS47 MKKFSRMPKSEGGSGGGAAGGGAGGAGAGAGCGSGGSSVGVRVFAVGRHQVTLEESLAEG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD GFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVS
::. :::::: .:..::::::.::: ::.:::::: ::..::::::::::.: ..:..:
CCDS47 GFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSIS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD SGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHR
. .::::::::..::.::::: ::..::::::: ::::::::::::::::::::::::::
CCDS47 D-NVWEVLILMEYCRAGQVVNQMNKKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHR
130 140 150 160 170
180 190 200 210 220 230
pF1KSD DLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYS
:::::::::.: :.::::::::::::: ::: .:::.::.:::::::::::::::.:::.
CCDS47 DLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD GKIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLE
:: ::::::::::::::::::.::::::::::::::::::::::::::...:::::.:::
CCDS47 GKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD PDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTD
:::..::::.:::::.::. ::.::. :..:: ::. ::::. ::::::.:.: :::.::
CCDS47 PDPEHRPDIFQVSYFAFKFAKKDCPVSNINNSSIPSALPEPMTASEAAARKSQIKARITD
300 310 320 330 340 350
360 370 380 390 400 410
pF1KSD PIPTTETSIAPRQRPKAGQ-TQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLAS
: :::::::::::::.. : .:..: :: . :: : . : :. : :
CCDS47 TIGPTETSIAPRQRPKANSATTATPSVLTIQSSATPVKVLA----PGEFGNHRPKGALRP
360 370 380 390 400 410
420 430 440 450 460 470
pF1KSD VPQPK---PQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQ
:. :.::.:: :: . :: . . . . : :::: .:
CCDS47 GNGPEILLGQGPPQQP--------PQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQ---QQ
420 430 440 450 460
480 490 500 510 520 530
pF1KSD QQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNF
:::::: ::: :::: : :: . : ...:.:.
CCDS47 QQQQQQQQQQQQQ------QQQQQQQQQHHHHH-------------------HHHLLQDA
470 480 490
540 550 560 570 580 590
pF1KSD YQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEP
:.:: :. ::::. :::. : . ::::. . : : .
CCDS47 YMQQYQHATQQQQM-----------------LQQQFLMHSVYQPQPSASQYPTMMPQYQ-
500 510 520 530 540
600 610 620 630 640 650
pF1KSD AIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASK
:: .:: .: : .:. .: .::. .: . : . ..::.
CCDS47 --QAFFQQQMLAQHQP-----SQQQASPEYLTSPQE--------FSPALVSYTSSLPAQV
550 560 570 580
660 670 680 690 700 710
pF1KSD STQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFSKLTAEEL
.: . ..: . ..:.. . . :.:.:. :: . : :::: .::::::: :::
CCDS47 GTIM------DSSYSANRSVADKEAIANFTNQKNISNPPDMSGWNPFGEDNFSKLTEEEL
590 600 610 620 630 640
720 730 740 750 760
pF1KSD LNKDFAKLGEGKHPEKLGG--SAESLIPGFQSTQGDAFATTSF--SAGTAEKRKGGQTVD
:...: : .. :. .. ...:: . : :... : .:. ::. ....
CCDS47 LDREFDLLRSNRLEERASSDKNVDSLSAPHNHPPEDPFGSVPFISHSGSPEKKAEHSSIN
650 660 670 680 690 700
770 780 790 800 810 820
pF1KSD SGLPLLSVSDPFIPLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIGKVII
CCDS47 QENGTANPIKNGKTSPASKDQRTGKKTSVQGQVQKGNDESESDFESDPPSPKSSEEEEQD
710 720 730 740 750 760
863 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 04:43:49 2016 done: Thu Nov 3 04:43:49 2016
Total Scan time: 4.670 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]