FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1048, 863 aa 1>>>pF1KSDA1048 863 - 863 aa - 863 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 17.9252+/-0.00056; mu= -34.3986+/- 0.035 mean_var=968.1331+/-204.567, 0's: 0 Z-trim(123.8): 100 B-trim: 0 in 0/58 Lambda= 0.041220 statistics sampled from 44082 (44214) to 44082 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.518), width: 16 Scan time: 13.810 The best scores are: opt bits E(85289) NP_055726 (OMIM: 616405) AP2-associated protein ki ( 961) 5559 346.7 2.9e-94 XP_016863483 (OMIM: 602052) PREDICTED: cyclin-G-as (1197) 666 55.9 1.4e-06 XP_005272327 (OMIM: 602052) PREDICTED: cyclin-G-as (1236) 666 55.9 1.4e-06 XP_011511733 (OMIM: 602052) PREDICTED: cyclin-G-as (1272) 666 55.9 1.4e-06 XP_005272325 (OMIM: 602052) PREDICTED: cyclin-G-as (1300) 666 55.9 1.4e-06 XP_011511730 (OMIM: 602052) PREDICTED: cyclin-G-as (1306) 666 55.9 1.4e-06 NP_005246 (OMIM: 602052) cyclin-G-associated kinas (1311) 666 55.9 1.4e-06 XP_011511728 (OMIM: 602052) PREDICTED: cyclin-G-as (1344) 666 55.9 1.5e-06 XP_011511727 (OMIM: 602052) PREDICTED: cyclin-G-as (1355) 666 55.9 1.5e-06 XP_011511731 (OMIM: 602052) PREDICTED: cyclin-G-as (1293) 536 48.2 0.0003 XP_011511734 (OMIM: 602052) PREDICTED: cyclin-G-as (1267) 534 48.0 0.00033 NP_001305063 (OMIM: 602052) cyclin-G-associated ki (1232) 476 44.6 0.0035 XP_011511732 (OMIM: 602052) PREDICTED: cyclin-G-as (1276) 476 44.6 0.0036 XP_016863482 (OMIM: 602052) PREDICTED: cyclin-G-as (1219) 459 43.6 0.007 XP_011511736 (OMIM: 602052) PREDICTED: cyclin-G-as (1219) 459 43.6 0.007 >>NP_055726 (OMIM: 616405) AP2-associated protein kinase (961 aa) initn: 5777 init1: 5559 opt: 5559 Z-score: 1813.2 bits: 346.7 E(85289): 2.9e-94 Smith-Waterman score: 5559; 99.0% identity (99.6% similar) in 833 aa overlap (1-833:1-833) 10 20 30 40 50 60 pF1KSD MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 FLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIIT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD TKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD QAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD QQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD PKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFSKLTAEELLNKDFAKLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFSKLTAEELLNKDFAKLG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EGKHPEKLGGSAESLIPGFQSTQGDAFATTSFSAGTAEKRKGGQTVDSGLPLLSVSDPFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EGKHPEKLGGSAESLIPGFQSTQGDAFATTSFSAGTAEKRKGGQTVDSGLPLLSVSDPFI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIGKVIISVSSVMHDMCACF :::::::::::::::::::::::::::::::::::::::::: :. ..: :.. NP_055 PLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIEKADVAVESLIPGLEPPV 790 800 810 820 830 840 850 860 pF1KSD KNDKYLVNQSLGNSPATPEAKAI NP_055 PQRLPSQTESVTSNRTDSLTGEDSLLDCSLLSNPTTDLLEEFAPTAISAPVHKAAEDSNL 850 860 870 880 890 900 >>XP_016863483 (OMIM: 602052) PREDICTED: cyclin-G-associ (1197 aa) initn: 640 init1: 213 opt: 666 Z-score: 239.4 bits: 55.9 E(85289): 1.4e-06 Smith-Waterman score: 666; 37.8% identity (67.4% similar) in 344 aa overlap (17-349:13-348) 10 20 30 40 50 60 pF1KSD MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV : :: ::... . : ..:.. .:. .. : .::::::::.: XP_016 MSLLQSALDFLAGPGSLGGASGRDQ--SDFVGQTVELGELRLRVRRVLAEGGFAFV 10 20 30 40 50 70 80 90 100 110 pF1KSD FLVR-TSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDS-SINNVSS-- . .. ...: . ::::.. :.:. .. .:. .:. :::: ::: . .. ::.. : XP_016 YEAQDVGSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD GDVWEVLILMDFCRGGQVVNLMNQRLQTG-FTENEVLQIFCDTCEAVARLHQCKTPIIHR :.. : :.: ..:.: :.:..... . : .. . ::.:: .::.:: ..:. : ::::: XP_016 GQA-EFLLLTELCKG-QLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD DLKVENILLHDRGHYVLCDFGSATNKFQNPQ----TEGVNAVEDEIKKYTTLSYRAPEMV ::::::.:: ..: ::::::::. . :. .. ::.:: . :: ::.::.. XP_016 DLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEII 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD NLYSGKIITTKADIWALGCLLYKLCYFTLPFGE-SQVAICDGNFTIPDNSRYSQDMHCLI .:::. : : :::::::.:: ::. :: . ... : .:...:: .. .: :: XP_016 DLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLI 240 250 260 270 280 290 300 310 320 330 340 pF1KSD RYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQ-NSPIPAKLPEPVKASEAAAKKTQP : ::. .:..: .: .: . :.. ::. .::: : . . :. .. : XP_016 RAMLQVNPEERLSIAEVVH----QLQEIAAARNVNPKSPITELLEQNGGYGSATLSRGPP 300 310 320 330 340 350 360 370 380 390 400 pF1KSD KARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQP XP_016 PPVGPAGSGYSGGLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDL 350 360 370 380 390 400 >>XP_005272327 (OMIM: 602052) PREDICTED: cyclin-G-associ (1236 aa) initn: 588 init1: 213 opt: 666 Z-score: 239.2 bits: 55.9 E(85289): 1.4e-06 Smith-Waterman score: 666; 37.8% identity (67.4% similar) in 344 aa overlap (17-349:13-348) 10 20 30 40 50 60 pF1KSD MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV : :: ::... . : ..:.. .:. .. : .::::::::.: XP_005 MSLLQSALDFLAGPGSLGGASGRDQ--SDFVGQTVELGELRLRVRRVLAEGGFAFV 10 20 30 40 50 70 80 90 100 110 pF1KSD FLVR-TSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDS-SINNVSS-- . .. ...: . ::::.. :.:. .. .:. .:. :::: ::: . .. ::.. : XP_005 YEAQDVGSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD GDVWEVLILMDFCRGGQVVNLMNQRLQTG-FTENEVLQIFCDTCEAVARLHQCKTPIIHR :.. : :.: ..:.: :.:..... . : .. . ::.:: .::.:: ..:. : ::::: XP_005 GQA-EFLLLTELCKG-QLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD DLKVENILLHDRGHYVLCDFGSATNKFQNPQ----TEGVNAVEDEIKKYTTLSYRAPEMV ::::::.:: ..: ::::::::. . :. .. ::.:: . :: ::.::.. XP_005 DLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEII 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD NLYSGKIITTKADIWALGCLLYKLCYFTLPFGE-SQVAICDGNFTIPDNSRYSQDMHCLI .:::. : : :::::::.:: ::. :: . ... : .:...:: .. .: :: XP_005 DLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLI 240 250 260 270 280 290 300 310 320 330 340 pF1KSD RYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQ-NSPIPAKLPEPVKASEAAAKKTQP : ::. .:..: .: .: . :.. ::. .::: : . . :. .. : XP_005 RAMLQVNPEERLSIAEVVH----QLQEIAAARNVNPKSPITELLEQNGGYGSATLSRGPP 300 310 320 330 340 350 360 370 380 390 400 pF1KSD KARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQP XP_005 PPVGPAGSGYSGGLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDL 350 360 370 380 390 400 >>XP_011511733 (OMIM: 602052) PREDICTED: cyclin-G-associ (1272 aa) initn: 640 init1: 213 opt: 666 Z-score: 239.0 bits: 55.9 E(85289): 1.4e-06 Smith-Waterman score: 666; 37.8% identity (67.4% similar) in 344 aa overlap (17-349:13-348) 10 20 30 40 50 60 pF1KSD MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV : :: ::... . : ..:.. .:. .. : .::::::::.: XP_011 MSLLQSALDFLAGPGSLGGASGRDQ--SDFVGQTVELGELRLRVRRVLAEGGFAFV 10 20 30 40 50 70 80 90 100 110 pF1KSD FLVR-TSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDS-SINNVSS-- . .. ...: . ::::.. :.:. .. .:. .:. :::: ::: . .. ::.. : XP_011 YEAQDVGSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD GDVWEVLILMDFCRGGQVVNLMNQRLQTG-FTENEVLQIFCDTCEAVARLHQCKTPIIHR :.. : :.: ..:.: :.:..... . : .. . ::.:: .::.:: ..:. : ::::: XP_011 GQA-EFLLLTELCKG-QLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD DLKVENILLHDRGHYVLCDFGSATNKFQNPQ----TEGVNAVEDEIKKYTTLSYRAPEMV ::::::.:: ..: ::::::::. . :. .. ::.:: . :: ::.::.. XP_011 DLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEII 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD NLYSGKIITTKADIWALGCLLYKLCYFTLPFGE-SQVAICDGNFTIPDNSRYSQDMHCLI .:::. : : :::::::.:: ::. :: . ... : .:...:: .. .: :: XP_011 DLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLI 240 250 260 270 280 290 300 310 320 330 340 pF1KSD RYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQ-NSPIPAKLPEPVKASEAAAKKTQP : ::. .:..: .: .: . :.. ::. .::: : . . :. .. : XP_011 RAMLQVNPEERLSIAEVVH----QLQEIAAARNVNPKSPITELLEQNGGYGSATLSRGPP 300 310 320 330 340 350 360 370 380 390 400 pF1KSD KARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQP XP_011 PPVGPAGSGYSGGLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDL 350 360 370 380 390 400 >>XP_005272325 (OMIM: 602052) PREDICTED: cyclin-G-associ (1300 aa) initn: 657 init1: 213 opt: 666 Z-score: 238.9 bits: 55.9 E(85289): 1.4e-06 Smith-Waterman score: 666; 37.8% identity (67.4% similar) in 344 aa overlap (17-349:13-348) 10 20 30 40 50 60 pF1KSD MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV : :: ::... . : ..:.. .:. .. : .::::::::.: XP_005 MSLLQSALDFLAGPGSLGGASGRDQ--SDFVGQTVELGELRLRVRRVLAEGGFAFV 10 20 30 40 50 70 80 90 100 110 pF1KSD FLVR-TSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDS-SINNVSS-- . .. ...: . ::::.. :.:. .. .:. .:. :::: ::: . .. ::.. : XP_005 YEAQDVGSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD GDVWEVLILMDFCRGGQVVNLMNQRLQTG-FTENEVLQIFCDTCEAVARLHQCKTPIIHR :.. : :.: ..:.: :.:..... . : .. . ::.:: .::.:: ..:. : ::::: XP_005 GQA-EFLLLTELCKG-QLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD DLKVENILLHDRGHYVLCDFGSATNKFQNPQ----TEGVNAVEDEIKKYTTLSYRAPEMV ::::::.:: ..: ::::::::. . :. .. ::.:: . :: ::.::.. XP_005 DLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEII 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD NLYSGKIITTKADIWALGCLLYKLCYFTLPFGE-SQVAICDGNFTIPDNSRYSQDMHCLI .:::. : : :::::::.:: ::. :: . ... : .:...:: .. .: :: XP_005 DLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLI 240 250 260 270 280 290 300 310 320 330 340 pF1KSD RYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQ-NSPIPAKLPEPVKASEAAAKKTQP : ::. .:..: .: .: . :.. ::. .::: : . . :. .. : XP_005 RAMLQVNPEERLSIAEVVH----QLQEIAAARNVNPKSPITELLEQNGGYGSATLSRGPP 300 310 320 330 340 350 360 370 380 390 400 pF1KSD KARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQP XP_005 PPVGPAGSGYSGGLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDL 350 360 370 380 390 400 >>XP_011511730 (OMIM: 602052) PREDICTED: cyclin-G-associ (1306 aa) initn: 621 init1: 213 opt: 666 Z-score: 238.9 bits: 55.9 E(85289): 1.4e-06 Smith-Waterman score: 666; 37.8% identity (67.4% similar) in 344 aa overlap (17-349:13-348) 10 20 30 40 50 60 pF1KSD MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV : :: ::... . : ..:.. .:. .. : .::::::::.: XP_011 MSLLQSALDFLAGPGSLGGASGRDQ--SDFVGQTVELGELRLRVRRVLAEGGFAFV 10 20 30 40 50 70 80 90 100 110 pF1KSD FLVR-TSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDS-SINNVSS-- . .. ...: . ::::.. :.:. .. .:. .:. :::: ::: . .. ::.. : XP_011 YEAQDVGSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD GDVWEVLILMDFCRGGQVVNLMNQRLQTG-FTENEVLQIFCDTCEAVARLHQCKTPIIHR :.. : :.: ..:.: :.:..... . : .. . ::.:: .::.:: ..:. : ::::: XP_011 GQA-EFLLLTELCKG-QLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD DLKVENILLHDRGHYVLCDFGSATNKFQNPQ----TEGVNAVEDEIKKYTTLSYRAPEMV ::::::.:: ..: ::::::::. . :. .. ::.:: . :: ::.::.. XP_011 DLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEII 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD NLYSGKIITTKADIWALGCLLYKLCYFTLPFGE-SQVAICDGNFTIPDNSRYSQDMHCLI .:::. : : :::::::.:: ::. :: . ... : .:...:: .. .: :: XP_011 DLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLI 240 250 260 270 280 290 300 310 320 330 340 pF1KSD RYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQ-NSPIPAKLPEPVKASEAAAKKTQP : ::. .:..: .: .: . :.. ::. .::: : . . :. .. : XP_011 RAMLQVNPEERLSIAEVVH----QLQEIAAARNVNPKSPITELLEQNGGYGSATLSRGPP 300 310 320 330 340 350 360 370 380 390 400 pF1KSD KARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQP XP_011 PPVGPAGSGYSGGLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDL 350 360 370 380 390 400 >>NP_005246 (OMIM: 602052) cyclin-G-associated kinase is (1311 aa) initn: 621 init1: 213 opt: 666 Z-score: 238.9 bits: 55.9 E(85289): 1.4e-06 Smith-Waterman score: 666; 37.8% identity (67.4% similar) in 344 aa overlap (17-349:13-348) 10 20 30 40 50 60 pF1KSD MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV : :: ::... . : ..:.. .:. .. : .::::::::.: NP_005 MSLLQSALDFLAGPGSLGGASGRDQ--SDFVGQTVELGELRLRVRRVLAEGGFAFV 10 20 30 40 50 70 80 90 100 110 pF1KSD FLVR-TSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDS-SINNVSS-- . .. ...: . ::::.. :.:. .. .:. .:. :::: ::: . .. ::.. : NP_005 YEAQDVGSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD GDVWEVLILMDFCRGGQVVNLMNQRLQTG-FTENEVLQIFCDTCEAVARLHQCKTPIIHR :.. : :.: ..:.: :.:..... . : .. . ::.:: .::.:: ..:. : ::::: NP_005 GQA-EFLLLTELCKG-QLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD DLKVENILLHDRGHYVLCDFGSATNKFQNPQ----TEGVNAVEDEIKKYTTLSYRAPEMV ::::::.:: ..: ::::::::. . :. .. ::.:: . :: ::.::.. NP_005 DLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEII 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD NLYSGKIITTKADIWALGCLLYKLCYFTLPFGE-SQVAICDGNFTIPDNSRYSQDMHCLI .:::. : : :::::::.:: ::. :: . ... : .:...:: .. .: :: NP_005 DLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLI 240 250 260 270 280 290 300 310 320 330 340 pF1KSD RYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQ-NSPIPAKLPEPVKASEAAAKKTQP : ::. .:..: .: .: . :.. ::. .::: : . . :. .. : NP_005 RAMLQVNPEERLSIAEVVH----QLQEIAAARNVNPKSPITELLEQNGGYGSATLSRGPP 300 310 320 330 340 350 360 370 380 390 400 pF1KSD KARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQP NP_005 PPVGPAGSGYSGGLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDL 350 360 370 380 390 400 >>XP_011511728 (OMIM: 602052) PREDICTED: cyclin-G-associ (1344 aa) initn: 657 init1: 213 opt: 666 Z-score: 238.7 bits: 55.9 E(85289): 1.5e-06 Smith-Waterman score: 666; 37.8% identity (67.4% similar) in 344 aa overlap (17-349:13-348) 10 20 30 40 50 60 pF1KSD MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV : :: ::... . : ..:.. .:. .. : .::::::::.: XP_011 MSLLQSALDFLAGPGSLGGASGRDQ--SDFVGQTVELGELRLRVRRVLAEGGFAFV 10 20 30 40 50 70 80 90 100 110 pF1KSD FLVR-TSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDS-SINNVSS-- . .. ...: . ::::.. :.:. .. .:. .:. :::: ::: . .. ::.. : XP_011 YEAQDVGSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD GDVWEVLILMDFCRGGQVVNLMNQRLQTG-FTENEVLQIFCDTCEAVARLHQCKTPIIHR :.. : :.: ..:.: :.:..... . : .. . ::.:: .::.:: ..:. : ::::: XP_011 GQA-EFLLLTELCKG-QLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD DLKVENILLHDRGHYVLCDFGSATNKFQNPQ----TEGVNAVEDEIKKYTTLSYRAPEMV ::::::.:: ..: ::::::::. . :. .. ::.:: . :: ::.::.. XP_011 DLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEII 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD NLYSGKIITTKADIWALGCLLYKLCYFTLPFGE-SQVAICDGNFTIPDNSRYSQDMHCLI .:::. : : :::::::.:: ::. :: . ... : .:...:: .. .: :: XP_011 DLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLI 240 250 260 270 280 290 300 310 320 330 340 pF1KSD RYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQ-NSPIPAKLPEPVKASEAAAKKTQP : ::. .:..: .: .: . :.. ::. .::: : . . :. .. : XP_011 RAMLQVNPEERLSIAEVVH----QLQEIAAARNVNPKSPITELLEQNGGYGSATLSRGPP 300 310 320 330 340 350 360 370 380 390 400 pF1KSD KARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQP XP_011 PPVGPAGSGYSGGLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDL 350 360 370 380 390 400 >>XP_011511727 (OMIM: 602052) PREDICTED: cyclin-G-associ (1355 aa) initn: 621 init1: 213 opt: 666 Z-score: 238.7 bits: 55.9 E(85289): 1.5e-06 Smith-Waterman score: 666; 37.8% identity (67.4% similar) in 344 aa overlap (17-349:13-348) 10 20 30 40 50 60 pF1KSD MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIV : :: ::... . : ..:.. .:. .. : .::::::::.: XP_011 MSLLQSALDFLAGPGSLGGASGRDQ--SDFVGQTVELGELRLRVRRVLAEGGFAFV 10 20 30 40 50 70 80 90 100 110 pF1KSD FLVR-TSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDS-SINNVSS-- . .. ...: . ::::.. :.:. .. .:. .:. :::: ::: . .. ::.. : XP_011 YEAQDVGSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD GDVWEVLILMDFCRGGQVVNLMNQRLQTG-FTENEVLQIFCDTCEAVARLHQCKTPIIHR :.. : :.: ..:.: :.:..... . : .. . ::.:: .::.:: ..:. : ::::: XP_011 GQA-EFLLLTELCKG-QLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD DLKVENILLHDRGHYVLCDFGSATNKFQNPQ----TEGVNAVEDEIKKYTTLSYRAPEMV ::::::.:: ..: ::::::::. . :. .. ::.:: . :: ::.::.. XP_011 DLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEII 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD NLYSGKIITTKADIWALGCLLYKLCYFTLPFGE-SQVAICDGNFTIPDNSRYSQDMHCLI .:::. : : :::::::.:: ::. :: . ... : .:...:: .. .: :: XP_011 DLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLI 240 250 260 270 280 290 300 310 320 330 340 pF1KSD RYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQ-NSPIPAKLPEPVKASEAAAKKTQP : ::. .:..: .: .: . :.. ::. .::: : . . :. .. : XP_011 RAMLQVNPEERLSIAEVVH----QLQEIAAARNVNPKSPITELLEQNGGYGSATLSRGPP 300 310 320 330 340 350 360 370 380 390 400 pF1KSD KARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQP XP_011 PPVGPAGSGYSGGLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDL 350 360 370 380 390 400 >>XP_011511731 (OMIM: 602052) PREDICTED: cyclin-G-associ (1293 aa) initn: 487 init1: 213 opt: 536 Z-score: 197.2 bits: 48.2 E(85289): 0.0003 Smith-Waterman score: 536; 37.8% identity (65.5% similar) in 267 aa overlap (92-349:25-286) 70 80 90 100 110 120 pF1KSD LVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVW- :... :::: ::: . ... . .:. XP_011 MDFGVAVVSAQNCGHGYVRSPLTRQLQKKLSGHPNIVQFCSAASIGKEESDTGQ 10 20 30 40 50 130 140 150 160 170 pF1KSD -EVLILMDFCRGGQVVNLMNQRLQTG-FTENEVLQIFCDTCEAVARLHQCKTPIIHRDLK : :.: ..:.: :.:..... . : .. . ::.:: .::.:: ..:. : :::::::: XP_011 AEFLLLTELCKG-QLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHRDLK 60 70 80 90 100 110 180 190 200 210 220 230 pF1KSD VENILLHDRGHYVLCDFGSATNKFQNPQ----TEGVNAVEDEIKKYTTLSYRAPEMVNLY :::.:: ..: ::::::::. . :. .. ::.:: . :: ::.::...:: XP_011 VENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEIIDLY 120 130 140 150 160 170 240 250 260 270 280 290 pF1KSD SGKIITTKADIWALGCLLYKLCYFTLPFGE-SQVAICDGNFTIPDNSRYSQDMHCLIRYM :. : : :::::::.:: ::. :: . ... : .:...:: .. .: ::: : XP_011 SNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLIRAM 180 190 200 210 220 230 300 310 320 330 340 350 pF1KSD LEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQ-NSPIPAKLPEPVKASEAAAKKTQPKAR :. .:..: .: .: . :.. ::. .::: : . . :. .. : XP_011 LQVNPEERLSIAEVVH----QLQEIAAARNVNPKSPITELLEQNGGYGSATLSRGPPPPV 240 250 260 270 280 360 370 380 390 400 410 pF1KSD LTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLL XP_011 GPAGSGYSGGLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDLDIS 290 300 310 320 330 340 863 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:43:50 2016 done: Thu Nov 3 04:43:52 2016 Total Scan time: 13.810 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]