FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1052, 1455 aa
1>>>pF1KSDA1052 1455 - 1455 aa - 1455 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.3687+/-0.000499; mu= -23.4010+/- 0.031
mean_var=673.2301+/-143.016, 0's: 0 Z-trim(122.9): 309 B-trim: 0 in 0/58
Lambda= 0.049430
statistics sampled from 41311 (41663) to 41311 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.488), width: 16
Scan time: 19.480
The best scores are: opt bits E(85289)
NP_001258862 (OMIM: 614845,614848) centrosomal pro (1455) 9430 689.0 6.8e-197
XP_005271514 (OMIM: 614845,614848) PREDICTED: cent (1455) 9430 689.0 6.8e-197
XP_005271513 (OMIM: 614845,614848) PREDICTED: cent (1460) 9360 684.1 2.2e-195
NP_055771 (OMIM: 614845,614848) centrosomal protei (1460) 9360 684.1 2.2e-195
XP_006718851 (OMIM: 614845,614848) PREDICTED: cent (2025) 8496 622.6 9.8e-177
XP_005271510 (OMIM: 614845,614848) PREDICTED: cent (2022) 8455 619.6 7.5e-176
XP_006718857 (OMIM: 614845,614848) PREDICTED: cent (1434) 7669 563.5 4.3e-159
XP_016872861 (OMIM: 614845,614848) PREDICTED: cent (1996) 7669 563.6 5.5e-159
XP_016872871 (OMIM: 614845,614848) PREDICTED: cent (1454) 6334 468.3 2e-130
XP_016872870 (OMIM: 614845,614848) PREDICTED: cent (1454) 6334 468.3 2e-130
XP_016872858 (OMIM: 614845,614848) PREDICTED: cent (2034) 6329 468.0 3.3e-130
XP_016872859 (OMIM: 614845,614848) PREDICTED: cent (2033) 6312 466.8 7.6e-130
XP_016872874 (OMIM: 614845,614848) PREDICTED: cent (1367) 6300 465.8 1e-129
XP_016872872 (OMIM: 614845,614848) PREDICTED: cent (1434) 6300 465.8 1e-129
XP_016872873 (OMIM: 614845,614848) PREDICTED: cent (1434) 6300 465.8 1e-129
XP_016872860 (OMIM: 614845,614848) PREDICTED: cent (2016) 6305 466.3 1.1e-129
XP_016872869 (OMIM: 614845,614848) PREDICTED: cent (1480) 6300 465.8 1.1e-129
XP_016872868 (OMIM: 614845,614848) PREDICTED: cent (1480) 6300 465.8 1.1e-129
XP_016872866 (OMIM: 614845,614848) PREDICTED: cent (1960) 6300 465.9 1.3e-129
XP_016872864 (OMIM: 614845,614848) PREDICTED: cent (1996) 6300 465.9 1.3e-129
XP_016872863 (OMIM: 614845,614848) PREDICTED: cent (1996) 6300 465.9 1.3e-129
XP_016872862 (OMIM: 614845,614848) PREDICTED: cent (1996) 6300 465.9 1.3e-129
XP_016872855 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129
XP_011540976 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129
XP_016872854 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129
XP_016872856 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129
XP_016872853 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129
XP_016872857 (OMIM: 614845,614848) PREDICTED: cent (2041) 6283 464.7 3.2e-129
XP_016872865 (OMIM: 614845,614848) PREDICTED: cent (1993) 5665 420.7 5.8e-116
XP_016872875 (OMIM: 614845,614848) PREDICTED: cent (1339) 5643 419.0 1.3e-115
XP_016872867 (OMIM: 614845,614848) PREDICTED: cent (1923) 5133 382.7 1.5e-104
XP_011540992 (OMIM: 614845,614848) PREDICTED: cent ( 792) 968 85.4 1.9e-15
NP_115627 (OMIM: 611205) coiled-coil domain-contai (1476) 407 45.6 0.0034
XP_006718582 (OMIM: 611205) PREDICTED: coiled-coil (1560) 407 45.6 0.0036
XP_005245422 (OMIM: 609473) PREDICTED: cingulin is (1203) 403 45.2 0.0036
NP_065821 (OMIM: 609473) cingulin [Homo sapiens] (1203) 403 45.2 0.0036
NP_958783 (OMIM: 131950,226670,226730,601282,61213 (4515) 403 45.7 0.0098
XP_005251041 (OMIM: 131950,226670,226730,601282,61 (4520) 403 45.7 0.0098
XP_005251040 (OMIM: 131950,226670,226730,601282,61 (4524) 403 45.7 0.0098
XP_011515433 (OMIM: 131950,226670,226730,601282,61 (4524) 403 45.7 0.0098
NP_958781 (OMIM: 131950,226670,226730,601282,61213 (4525) 403 45.7 0.0098
XP_006716652 (OMIM: 131950,226670,226730,601282,61 (4529) 403 45.7 0.0098
XP_006716653 (OMIM: 131950,226670,226730,601282,61 (4529) 403 45.7 0.0098
XP_005251039 (OMIM: 131950,226670,226730,601282,61 (4530) 403 45.7 0.0098
NP_958780 (OMIM: 131950,226670,226730,601282,61213 (4533) 403 45.7 0.0098
XP_005251038 (OMIM: 131950,226670,226730,601282,61 (4538) 403 45.7 0.0099
NP_958784 (OMIM: 131950,226670,226730,601282,61213 (4547) 403 45.7 0.0099
NP_958786 (OMIM: 131950,226670,226730,601282,61213 (4547) 403 45.7 0.0099
NP_958785 (OMIM: 131950,226670,226730,601282,61213 (4551) 403 45.7 0.0099
XP_005251037 (OMIM: 131950,226670,226730,601282,61 (4552) 403 45.7 0.0099
>>NP_001258862 (OMIM: 614845,614848) centrosomal protein (1455 aa)
initn: 9430 init1: 9430 opt: 9430 Z-score: 3655.8 bits: 689.0 E(85289): 6.8e-197
Smith-Waterman score: 9430; 100.0% identity (100.0% similar) in 1455 aa overlap (1-1455:1-1455)
10 20 30 40 50 60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL
1390 1400 1410 1420 1430 1440
1450
pF1KSD QLGLDEHNRVKVYRF
:::::::::::::::
NP_001 QLGLDEHNRVKVYRF
1450
>>XP_005271514 (OMIM: 614845,614848) PREDICTED: centroso (1455 aa)
initn: 9430 init1: 9430 opt: 9430 Z-score: 3655.8 bits: 689.0 E(85289): 6.8e-197
Smith-Waterman score: 9430; 100.0% identity (100.0% similar) in 1455 aa overlap (1-1455:1-1455)
10 20 30 40 50 60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL
1390 1400 1410 1420 1430 1440
1450
pF1KSD QLGLDEHNRVKVYRF
:::::::::::::::
XP_005 QLGLDEHNRVKVYRF
1450
>>XP_005271513 (OMIM: 614845,614848) PREDICTED: centroso (1460 aa)
initn: 6313 init1: 4930 opt: 9360 Z-score: 3628.8 bits: 684.1 E(85289): 2.2e-195
Smith-Waterman score: 9360; 99.2% identity (99.2% similar) in 1463 aa overlap (1-1455:1-1460)
10 20 30 40 50 60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_005 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER---LSPPLPH
430 440 450 460 470
490 500 510 520 530 540
pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
600 610 620 630 640 650
670 680 690 700 710 720
pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
780 790 800 810 820 830
850 860 870 880 890 900
pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
840 850 860 870 880 890
910 920 930 940 950 960
pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250
pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPH--------LDSTPSLT
:::::::::::::::::::::::::::::::::::::::::::: .:::::::
XP_005 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLT
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
pF1KSD SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
pF1KSD LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
1320 1330 1340 1350 1360 1370
1380 1390 1400 1410 1420 1430
pF1KSD LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
1380 1390 1400 1410 1420 1430
1440 1450
pF1KSD PKATLSLLQLGLDEHNRVKVYRF
:::::::::::::::::::::::
XP_005 PKATLSLLQLGLDEHNRVKVYRF
1440 1450 1460
>>NP_055771 (OMIM: 614845,614848) centrosomal protein of (1460 aa)
initn: 6313 init1: 4930 opt: 9360 Z-score: 3628.8 bits: 684.1 E(85289): 2.2e-195
Smith-Waterman score: 9360; 99.2% identity (99.2% similar) in 1463 aa overlap (1-1455:1-1460)
10 20 30 40 50 60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_055 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER---LSPPLPH
430 440 450 460 470
490 500 510 520 530 540
pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
600 610 620 630 640 650
670 680 690 700 710 720
pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
780 790 800 810 820 830
850 860 870 880 890 900
pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
840 850 860 870 880 890
910 920 930 940 950 960
pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250
pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPH--------LDSTPSLT
:::::::::::::::::::::::::::::::::::::::::::: .:::::::
NP_055 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLT
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
pF1KSD SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
pF1KSD LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
1320 1330 1340 1350 1360 1370
1380 1390 1400 1410 1420 1430
pF1KSD LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
1380 1390 1400 1410 1420 1430
1440 1450
pF1KSD PKATLSLLQLGLDEHNRVKVYRF
:::::::::::::::::::::::
NP_055 PKATLSLLQLGLDEHNRVKVYRF
1440 1450 1460
>>XP_006718851 (OMIM: 614845,614848) PREDICTED: centroso (2025 aa)
initn: 9399 init1: 7125 opt: 8496 Z-score: 3293.9 bits: 622.6 E(85289): 9.8e-177
Smith-Waterman score: 8496; 99.3% identity (99.4% similar) in 1332 aa overlap (132-1455:694-2025)
110 120 130 140 150 160
pF1KSD KLSTSGAIKKKKKKKEKKDKKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
::::::::::::::::::::::::::::::
XP_006 SSSTLRQGLVQQSSSRGLTTEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
670 680 690 700 710 720
170 180 190 200 210 220
pF1KSD RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
730 740 750 760 770 780
230 240 250 260 270 280
pF1KSD DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP
790 800 810 820 830 840
290 300 310 320 330 340
pF1KSD CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
850 860 870 880 890 900
350 360 370 380 390 400
pF1KSD ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
910 920 930 940 950 960
410 420 430 440 450 460
pF1KSD ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
970 980 990 1000 1010 1020
470 480 490 500 510 520
pF1KSD KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
1030 1040 1050 1060 1070 1080
530 540 550 560 570 580
pF1KSD SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
1090 1100 1110 1120 1130 1140
590 600 610 620 630 640
pF1KSD EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
1150 1160 1170 1180 1190 1200
650 660 670 680 690 700
pF1KSD QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
1210 1220 1230 1240 1250 1260
710 720 730 740 750 760
pF1KSD LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
1270 1280 1290 1300 1310 1320
770 780 790 800 810 820
pF1KSD RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
1330 1340 1350 1360 1370 1380
830 840 850 860 870 880
pF1KSD HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
1390 1400 1410 1420 1430 1440
890 900 910 920 930 940
pF1KSD ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
1450 1460 1470 1480 1490 1500
950 960 970 980 990 1000
pF1KSD KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
1510 1520 1530 1540 1550 1560
1010 1020 1030 1040 1050 1060
pF1KSD EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
1570 1580 1590 1600 1610 1620
1070 1080 1090 1100 1110 1120
pF1KSD PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
1630 1640 1650 1660 1670 1680
1130 1140 1150 1160 1170 1180
pF1KSD QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
1690 1700 1710 1720 1730 1740
1190 1200 1210 1220 1230 1240
pF1KSD MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
1750 1760 1770 1780 1790 1800
1250 1260 1270 1280 1290
pF1KSD PPH--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
::: .::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
1810 1820 1830 1840 1850 1860
1300 1310 1320 1330 1340 1350
pF1KSD AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
1870 1880 1890 1900 1910 1920
1360 1370 1380 1390 1400 1410
pF1KSD KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
1930 1940 1950 1960 1970 1980
1420 1430 1440 1450
pF1KSD WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
::::::::::::::::::::::::::::::::::::::::::
XP_006 WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
1990 2000 2010 2020
>--
initn: 1003 init1: 905 opt: 976 Z-score: 395.7 bits: 86.3 E(85289): 2.7e-15
Smith-Waterman score: 1001; 38.0% identity (56.4% similar) in 731 aa overlap (1-626:1-693)
10 20 30 40 50 60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
70 80 90 100 110 120
130 140 150
pF1KSD KKDRDPPKSSL------------ALGSSLAPVHVPLGGLAPL---------------RG-
::::::::::: .. ::.: .: ::: : .:
XP_006 KKDRDPPKSSLETQPEEGLLPPSSFLCSLSPPSAP--GLADLDLDQEMQAISEGSYNKGK
130 140 150 160 170
160 170 180 190
pF1KSD ----LVDTP---PSAL-RGSQSVSLG--SSVES---------GR---QLGELMLPSQGLK
: ::: .:: : : .: : :.... :: : . . .:::.
XP_006 SPGMLGDTPWRFMGALPRKLQPLSKGQPSQIHQVFADMEKILGRAPAQCRRELGDQQGLE
180 190 200 210 220 230
200 210 220 230
pF1KSD T--SAYTKGLLGSIYEDKTALSL------LGL------GEETNEEDEEESDNQ-SVHSS-
.: : :: . : . :: : : .: :: :: ::::.
XP_006 KLQKATEKIYLGFSDPETEELEMRSRQQKLGTPAPQNTGLLQNMQDVVESRNQASVHSKL
240 250 260 270 280 290
240 250 260 270 280
pF1KSD SEPLRNLHL-------DIGAL-----GGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPC
:: ...: : ... : ::: . . . :.:::. ::.: ..: :
XP_006 SEAIKGLPLKGEQHSHSLAKLSPTGPGGD-KGQSPIPMSSPEEEP--SLSSCSSGHMLPA
300 310 320 330 340 350
290 300 310 320
pF1KSD KPS------SPGADSSLSSAVGKGRQ-GSGAR----PGLPEKEENE---KSEPKICRNLV
. : :: : : ... :.: . ::: : ::: .. .. :. : :.
XP_006 RKSKLLLDSSPTEDLSWQGVPGEGGSIGSGRRRREPPGLWMEQVSKLVNKDIPGSCK---
360 370 380 390 400 410
330 340 350 360 370 380
pF1KSD TPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEL--
...:. : :: .. :. . : . : :..: . : .:. : :
XP_006 --ETEPSDPEALGASAEDLPQGLLLIPPE-TLASEPAQNPLLGRAPEEPPASEKRQALGS
420 430 440 450 460
390 400 410 420 430 440
pF1KSD -EISEHMKEPQLSD-SIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPL
:. . ..:.:: .. :. .: . : .. :: :::: . . :
XP_006 AELPYKDQKPSLSGPDLESSSSSSSN------SNLASHLG-----SPVLDEV---NNFPW
470 480 490 500 510
450 460 470 480 490 500
pF1KSD GIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPL-PHEERAQSPPRSLATEEEPPQGPEG
... :. ...: ......:: : ...:: : :: . ::: . . :. :
XP_006 NLQ----SSRGSEEGMAQSDSGL--RDQHFSPFLDPHMSHMQSPDEEQSESEDYS---ED
520 530 540 550 560
510 520 530 540 550 560
pF1KSD QPEWKEAEELGEDSAASLSLQLSLQREQAP---SPPAACEKGKEQHSQAEELGPGQEEAE
: ... .. . : .: : . .. : : ..: . :. .. : :..::
XP_006 QRFYQHILQMVKISRWPEGLGLPESMQDMPCRHSASTVCCMAAESSRMSSE---GEHEAI
570 580 590 600 610 620
570 580 590 600 610
pF1KSD DPEEKVA--VSPTPPV--SPEVRSTEPVAPPEQLSEAALKAMEEAVAQ-VLEQDQRHLLE
:. . .: : . :. . : : : ..: .. .. : ...:.. . :
XP_006 RVMERDSRFLSWEPELLEHPQEVALAP-AWQEASQQAHFQPSSSTLRQGLVQQSSSRGLT
630 640 650 660 670 680
620 630 640 650 660 670
pF1KSD SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW
.. :::.: .
XP_006 TEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
690 700 710 720 730 740
>>XP_005271510 (OMIM: 614845,614848) PREDICTED: centroso (2022 aa)
initn: 7204 init1: 4930 opt: 8455 Z-score: 3278.1 bits: 619.6 E(85289): 7.5e-176
Smith-Waterman score: 8455; 99.1% identity (99.2% similar) in 1332 aa overlap (132-1455:694-2022)
110 120 130 140 150 160
pF1KSD KLSTSGAIKKKKKKKEKKDKKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
::::::::::::::::::::::::::::::
XP_005 SSSTLRQGLVQQSSSRGLTTEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
670 680 690 700 710 720
170 180 190 200 210 220
pF1KSD RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
730 740 750 760 770 780
230 240 250 260 270 280
pF1KSD DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP
790 800 810 820 830 840
290 300 310 320 330 340
pF1KSD CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
850 860 870 880 890 900
350 360 370 380 390 400
pF1KSD ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
910 920 930 940 950 960
410 420 430 440 450 460
pF1KSD ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
970 980 990 1000 1010 1020
470 480 490 500 510 520
pF1KSD KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQSKGLEE---RLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
1030 1040 1050 1060 1070 1080
530 540 550 560 570 580
pF1KSD SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
1090 1100 1110 1120 1130 1140
590 600 610 620 630 640
pF1KSD EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
1150 1160 1170 1180 1190 1200
650 660 670 680 690 700
pF1KSD QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
1210 1220 1230 1240 1250 1260
710 720 730 740 750 760
pF1KSD LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
1270 1280 1290 1300 1310 1320
770 780 790 800 810 820
pF1KSD RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
1330 1340 1350 1360 1370 1380
830 840 850 860 870 880
pF1KSD HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
1390 1400 1410 1420 1430 1440
890 900 910 920 930 940
pF1KSD ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
1450 1460 1470 1480 1490 1500
950 960 970 980 990 1000
pF1KSD KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
1510 1520 1530 1540 1550 1560
1010 1020 1030 1040 1050 1060
pF1KSD EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
1570 1580 1590 1600 1610 1620
1070 1080 1090 1100 1110 1120
pF1KSD PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
1630 1640 1650 1660 1670 1680
1130 1140 1150 1160 1170 1180
pF1KSD QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
1690 1700 1710 1720 1730 1740
1190 1200 1210 1220 1230 1240
pF1KSD MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
1750 1760 1770 1780 1790 1800
1250 1260 1270 1280 1290
pF1KSD PPH--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
::: .::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
1810 1820 1830 1840 1850 1860
1300 1310 1320 1330 1340 1350
pF1KSD AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
1870 1880 1890 1900 1910 1920
1360 1370 1380 1390 1400 1410
pF1KSD KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
1930 1940 1950 1960 1970 1980
1420 1430 1440 1450
pF1KSD WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
::::::::::::::::::::::::::::::::::::::::::
XP_005 WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
1990 2000 2010 2020
>--
initn: 1003 init1: 905 opt: 976 Z-score: 395.7 bits: 86.3 E(85289): 2.7e-15
Smith-Waterman score: 1001; 38.0% identity (56.4% similar) in 731 aa overlap (1-626:1-693)
10 20 30 40 50 60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
70 80 90 100 110 120
130 140 150
pF1KSD KKDRDPPKSSL------------ALGSSLAPVHVPLGGLAPL---------------RG-
::::::::::: .. ::.: .: ::: : .:
XP_005 KKDRDPPKSSLETQPEEGLLPPSSFLCSLSPPSAP--GLADLDLDQEMQAISEGSYNKGK
130 140 150 160 170
160 170 180 190
pF1KSD ----LVDTP---PSAL-RGSQSVSLG--SSVES---------GR---QLGELMLPSQGLK
: ::: .:: : : .: : :.... :: : . . .:::.
XP_005 SPGMLGDTPWRFMGALPRKLQPLSKGQPSQIHQVFADMEKILGRAPAQCRRELGDQQGLE
180 190 200 210 220 230
200 210 220 230
pF1KSD T--SAYTKGLLGSIYEDKTALSL------LGL------GEETNEEDEEESDNQ-SVHSS-
.: : :: . : . :: : : .: :: :: ::::.
XP_005 KLQKATEKIYLGFSDPETEELEMRSRQQKLGTPAPQNTGLLQNMQDVVESRNQASVHSKL
240 250 260 270 280 290
240 250 260 270 280
pF1KSD SEPLRNLHL-------DIGAL-----GGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPC
:: ...: : ... : ::: . . . :.:::. ::.: ..: :
XP_005 SEAIKGLPLKGEQHSHSLAKLSPTGPGGD-KGQSPIPMSSPEEEP--SLSSCSSGHMLPA
300 310 320 330 340 350
290 300 310 320
pF1KSD KPS------SPGADSSLSSAVGKGRQ-GSGAR----PGLPEKEENE---KSEPKICRNLV
. : :: : : ... :.: . ::: : ::: .. .. :. : :.
XP_005 RKSKLLLDSSPTEDLSWQGVPGEGGSIGSGRRRREPPGLWMEQVSKLVNKDIPGSCK---
360 370 380 390 400 410
330 340 350 360 370 380
pF1KSD TPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEL--
...:. : :: .. :. . : . : :..: . : .:. : :
XP_005 --ETEPSDPEALGASAEDLPQGLLLIPPE-TLASEPAQNPLLGRAPEEPPASEKRQALGS
420 430 440 450 460
390 400 410 420 430 440
pF1KSD -EISEHMKEPQLSD-SIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPL
:. . ..:.:: .. :. .: . : .. :: :::: . . :
XP_005 AELPYKDQKPSLSGPDLESSSSSSSN------SNLASHLG-----SPVLDEV---NNFPW
470 480 490 500 510
450 460 470 480 490 500
pF1KSD GIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPL-PHEERAQSPPRSLATEEEPPQGPEG
... :. ...: ......:: : ...:: : :: . ::: . . :. :
XP_005 NLQ----SSRGSEEGMAQSDSGL--RDQHFSPFLDPHMSHMQSPDEEQSESEDYS---ED
520 530 540 550 560
510 520 530 540 550 560
pF1KSD QPEWKEAEELGEDSAASLSLQLSLQREQAP---SPPAACEKGKEQHSQAEELGPGQEEAE
: ... .. . : .: : . .. : : ..: . :. .. : :..::
XP_005 QRFYQHILQMVKISRWPEGLGLPESMQDMPCRHSASTVCCMAAESSRMSSE---GEHEAI
570 580 590 600 610 620
570 580 590 600 610
pF1KSD DPEEKVA--VSPTPPV--SPEVRSTEPVAPPEQLSEAALKAMEEAVAQ-VLEQDQRHLLE
:. . .: : . :. . : : : ..: .. .. : ...:.. . :
XP_005 RVMERDSRFLSWEPELLEHPQEVALAP-AWQEASQQAHFQPSSSTLRQGLVQQSSSRGLT
630 640 650 660 670 680
620 630 640 650 660 670
pF1KSD SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW
.. :::.: .
XP_005 TEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
690 700 710 720 730 740
>>XP_006718857 (OMIM: 614845,614848) PREDICTED: centroso (1434 aa)
initn: 7831 init1: 4930 opt: 7669 Z-score: 2977.2 bits: 563.5 E(85289): 4.3e-159
Smith-Waterman score: 9125; 97.4% identity (97.5% similar) in 1463 aa overlap (1-1455:1-1434)
10 20 30 40 50 60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQ-----------
190 200 210 220
250 260 270 280 290 300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
:::::::::::::::::::::::::::::::::::::::::::::
XP_006 ---------------ESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
230 240 250 260 270
310 320 330 340 350 360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
340 350 360 370 380 390
430 440 450 460 470 480
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_006 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER---LSPPLPH
400 410 420 430 440 450
490 500 510 520 530 540
pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
460 470 480 490 500 510
550 560 570 580 590 600
pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
520 530 540 550 560 570
610 620 630 640 650 660
pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
580 590 600 610 620 630
670 680 690 700 710 720
pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
640 650 660 670 680 690
730 740 750 760 770 780
pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
700 710 720 730 740 750
790 800 810 820 830 840
pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
760 770 780 790 800 810
850 860 870 880 890 900
pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
820 830 840 850 860 870
910 920 930 940 950 960
pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250
pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPH--------LDSTPSLT
:::::::::::::::::::::::::::::::::::::::::::: .:::::::
XP_006 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLT
1180 1190 1200 1210 1220 1230
1260 1270 1280 1290 1300 1310
pF1KSD SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
1240 1250 1260 1270 1280 1290
1320 1330 1340 1350 1360 1370
pF1KSD LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
1300 1310 1320 1330 1340 1350
1380 1390 1400 1410 1420 1430
pF1KSD LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
1360 1370 1380 1390 1400 1410
1440 1450
pF1KSD PKATLSLLQLGLDEHNRVKVYRF
:::::::::::::::::::::::
XP_006 PKATLSLLQLGLDEHNRVKVYRF
1420 1430
>>XP_016872861 (OMIM: 614845,614848) PREDICTED: centroso (1996 aa)
initn: 7817 init1: 4930 opt: 7669 Z-score: 2975.3 bits: 563.6 E(85289): 5.5e-159
Smith-Waterman score: 8220; 97.1% identity (97.2% similar) in 1332 aa overlap (132-1455:694-1996)
110 120 130 140 150 160
pF1KSD KLSTSGAIKKKKKKKEKKDKKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
::::::::::::::::::::::::::::::
XP_016 SSSTLRQGLVQQSSSRGLTTEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
670 680 690 700 710 720
170 180 190 200 210 220
pF1KSD RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
730 740 750 760 770 780
230 240 250 260 270 280
pF1KSD DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP
:::::::: ::::::::::::::::::::::::::
XP_016 DEEESDNQ--------------------------ESLRTSQPEEKKDVSLDSDAAGPPTP
790 800 810
290 300 310 320 330 340
pF1KSD CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
820 830 840 850 860 870
350 360 370 380 390 400
pF1KSD ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
880 890 900 910 920 930
410 420 430 440 450 460
pF1KSD ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
940 950 960 970 980 990
470 480 490 500 510 520
pF1KSD KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQSKGLEE---RLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
1000 1010 1020 1030 1040 1050
530 540 550 560 570 580
pF1KSD SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
1060 1070 1080 1090 1100 1110
590 600 610 620 630 640
pF1KSD EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
1120 1130 1140 1150 1160 1170
650 660 670 680 690 700
pF1KSD QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
1180 1190 1200 1210 1220 1230
710 720 730 740 750 760
pF1KSD LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
1240 1250 1260 1270 1280 1290
770 780 790 800 810 820
pF1KSD RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
1300 1310 1320 1330 1340 1350
830 840 850 860 870 880
pF1KSD HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
1360 1370 1380 1390 1400 1410
890 900 910 920 930 940
pF1KSD ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
1420 1430 1440 1450 1460 1470
950 960 970 980 990 1000
pF1KSD KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
1480 1490 1500 1510 1520 1530
1010 1020 1030 1040 1050 1060
pF1KSD EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
1540 1550 1560 1570 1580 1590
1070 1080 1090 1100 1110 1120
pF1KSD PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
1600 1610 1620 1630 1640 1650
1130 1140 1150 1160 1170 1180
pF1KSD QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
1660 1670 1680 1690 1700 1710
1190 1200 1210 1220 1230 1240
pF1KSD MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
1720 1730 1740 1750 1760 1770
1250 1260 1270 1280 1290
pF1KSD PPH--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
::: .::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
1780 1790 1800 1810 1820 1830
1300 1310 1320 1330 1340 1350
pF1KSD AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
1840 1850 1860 1870 1880 1890
1360 1370 1380 1390 1400 1410
pF1KSD KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
1900 1910 1920 1930 1940 1950
1420 1430 1440 1450
pF1KSD WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
::::::::::::::::::::::::::::::::::::::::::
XP_016 WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
1960 1970 1980 1990
>--
initn: 1003 init1: 905 opt: 976 Z-score: 395.8 bits: 86.3 E(85289): 2.6e-15
Smith-Waterman score: 1001; 38.0% identity (56.4% similar) in 731 aa overlap (1-626:1-693)
10 20 30 40 50 60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
70 80 90 100 110 120
130 140 150
pF1KSD KKDRDPPKSSL------------ALGSSLAPVHVPLGGLAPL---------------RG-
::::::::::: .. ::.: .: ::: : .:
XP_016 KKDRDPPKSSLETQPEEGLLPPSSFLCSLSPPSAP--GLADLDLDQEMQAISEGSYNKGK
130 140 150 160 170
160 170 180 190
pF1KSD ----LVDTP---PSAL-RGSQSVSLG--SSVES---------GR---QLGELMLPSQGLK
: ::: .:: : : .: : :.... :: : . . .:::.
XP_016 SPGMLGDTPWRFMGALPRKLQPLSKGQPSQIHQVFADMEKILGRAPAQCRRELGDQQGLE
180 190 200 210 220 230
200 210 220 230
pF1KSD T--SAYTKGLLGSIYEDKTALSL------LGL------GEETNEEDEEESDNQ-SVHSS-
.: : :: . : . :: : : .: :: :: ::::.
XP_016 KLQKATEKIYLGFSDPETEELEMRSRQQKLGTPAPQNTGLLQNMQDVVESRNQASVHSKL
240 250 260 270 280 290
240 250 260 270 280
pF1KSD SEPLRNLHL-------DIGAL-----GGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPC
:: ...: : ... : ::: . . . :.:::. ::.: ..: :
XP_016 SEAIKGLPLKGEQHSHSLAKLSPTGPGGD-KGQSPIPMSSPEEEP--SLSSCSSGHMLPA
300 310 320 330 340 350
290 300 310 320
pF1KSD KPS------SPGADSSLSSAVGKGRQ-GSGAR----PGLPEKEENE---KSEPKICRNLV
. : :: : : ... :.: . ::: : ::: .. .. :. : :.
XP_016 RKSKLLLDSSPTEDLSWQGVPGEGGSIGSGRRRREPPGLWMEQVSKLVNKDIPGSCK---
360 370 380 390 400 410
330 340 350 360 370 380
pF1KSD TPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEL--
...:. : :: .. :. . : . : :..: . : .:. : :
XP_016 --ETEPSDPEALGASAEDLPQGLLLIPPE-TLASEPAQNPLLGRAPEEPPASEKRQALGS
420 430 440 450 460
390 400 410 420 430 440
pF1KSD -EISEHMKEPQLSD-SIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPL
:. . ..:.:: .. :. .: . : .. :: :::: . . :
XP_016 AELPYKDQKPSLSGPDLESSSSSSSN------SNLASHLG-----SPVLDEV---NNFPW
470 480 490 500 510
450 460 470 480 490 500
pF1KSD GIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPL-PHEERAQSPPRSLATEEEPPQGPEG
... :. ...: ......:: : ...:: : :: . ::: . . :. :
XP_016 NLQ----SSRGSEEGMAQSDSGL--RDQHFSPFLDPHMSHMQSPDEEQSESEDYS---ED
520 530 540 550 560
510 520 530 540 550 560
pF1KSD QPEWKEAEELGEDSAASLSLQLSLQREQAP---SPPAACEKGKEQHSQAEELGPGQEEAE
: ... .. . : .: : . .. : : ..: . :. .. : :..::
XP_016 QRFYQHILQMVKISRWPEGLGLPESMQDMPCRHSASTVCCMAAESSRMSSE---GEHEAI
570 580 590 600 610 620
570 580 590 600 610
pF1KSD DPEEKVA--VSPTPPV--SPEVRSTEPVAPPEQLSEAALKAMEEAVAQ-VLEQDQRHLLE
:. . .: : . :. . : : : ..: .. .. : ...:.. . :
XP_016 RVMERDSRFLSWEPELLEHPQEVALAP-AWQEASQQAHFQPSSSTLRQGLVQQSSSRGLT
630 640 650 660 670 680
620 630 640 650 660 670
pF1KSD SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW
.. :::.: .
XP_016 TEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
690 700 710 720 730 740
>>XP_016872871 (OMIM: 614845,614848) PREDICTED: centroso (1454 aa)
initn: 7810 init1: 4909 opt: 6334 Z-score: 2462.6 bits: 468.3 E(85289): 2e-130
Smith-Waterman score: 9093; 96.3% identity (96.4% similar) in 1480 aa overlap (1-1455:1-1454)
10 20 30 40 50 60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQ-----------
190 200 210 220
250 260 270 280 290 300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 ---------------ESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
230 240 250 260 270
310 320 330 340 350 360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
340 350 360 370 380 390
430 440 450 460 470
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER----------
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEESSLPALQMEGP
400 410 420 430 440 450
480 490 500 510 520
pF1KSD -------YHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSAALPGLTRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL
460 470 480 490 500 510
530 540 550 560 570 580
pF1KSD QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP
520 530 540 550 560 570
590 600 610 620 630 640
pF1KSD VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK
580 590 600 610 620 630
650 660 670 680 690 700
pF1KSD EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR
640 650 660 670 680 690
710 720 730 740 750 760
pF1KSD EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK
700 710 720 730 740 750
770 780 790 800 810 820
pF1KSD EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ
760 770 780 790 800 810
830 840 850 860 870 880
pF1KSD KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL
820 830 840 850 860 870
890 900 910 920 930 940
pF1KSD LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA
880 890 900 910 920 930
950 960 970 980 990 1000
pF1KSD RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI
940 950 960 970 980 990
1010 1020 1030 1040 1050 1060
pF1KSD LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD
1000 1010 1020 1030 1040 1050
1070 1080 1090 1100 1110 1120
pF1KSD LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ
1060 1070 1080 1090 1100 1110
1130 1140 1150 1160 1170 1180
pF1KSD TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR
1120 1130 1140 1150 1160 1170
1190 1200 1210 1220 1230 1240
pF1KSD KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP
1180 1190 1200 1210 1220 1230
1250 1260 1270 1280 1290
pF1KSD H--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ
: .::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ
1240 1250 1260 1270 1280 1290
1300 1310 1320 1330 1340 1350
pF1KSD LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW
1300 1310 1320 1330 1340 1350
1360 1370 1380 1390 1400 1410
pF1KSD RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL
1360 1370 1380 1390 1400 1410
1420 1430 1440 1450
pF1KSD ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
::::::::::::::::::::::::::::::::::::::::
XP_016 ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
1420 1430 1440 1450
>>XP_016872870 (OMIM: 614845,614848) PREDICTED: centroso (1454 aa)
initn: 7810 init1: 4909 opt: 6334 Z-score: 2462.6 bits: 468.3 E(85289): 2e-130
Smith-Waterman score: 9093; 96.3% identity (96.4% similar) in 1480 aa overlap (1-1455:1-1454)
10 20 30 40 50 60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQ-----------
190 200 210 220
250 260 270 280 290 300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 ---------------ESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
230 240 250 260 270
310 320 330 340 350 360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
340 350 360 370 380 390
430 440 450 460 470
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER----------
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEESSLPALQMEGP
400 410 420 430 440 450
480 490 500 510 520
pF1KSD -------YHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSAALPGLTRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL
460 470 480 490 500 510
530 540 550 560 570 580
pF1KSD QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP
520 530 540 550 560 570
590 600 610 620 630 640
pF1KSD VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK
580 590 600 610 620 630
650 660 670 680 690 700
pF1KSD EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR
640 650 660 670 680 690
710 720 730 740 750 760
pF1KSD EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK
700 710 720 730 740 750
770 780 790 800 810 820
pF1KSD EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ
760 770 780 790 800 810
830 840 850 860 870 880
pF1KSD KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL
820 830 840 850 860 870
890 900 910 920 930 940
pF1KSD LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA
880 890 900 910 920 930
950 960 970 980 990 1000
pF1KSD RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI
940 950 960 970 980 990
1010 1020 1030 1040 1050 1060
pF1KSD LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD
1000 1010 1020 1030 1040 1050
1070 1080 1090 1100 1110 1120
pF1KSD LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ
1060 1070 1080 1090 1100 1110
1130 1140 1150 1160 1170 1180
pF1KSD TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR
1120 1130 1140 1150 1160 1170
1190 1200 1210 1220 1230 1240
pF1KSD KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP
1180 1190 1200 1210 1220 1230
1250 1260 1270 1280 1290
pF1KSD H--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ
: .::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ
1240 1250 1260 1270 1280 1290
1300 1310 1320 1330 1340 1350
pF1KSD LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW
1300 1310 1320 1330 1340 1350
1360 1370 1380 1390 1400 1410
pF1KSD RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL
1360 1370 1380 1390 1400 1410
1420 1430 1440 1450
pF1KSD ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
::::::::::::::::::::::::::::::::::::::::
XP_016 ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
1420 1430 1440 1450
1455 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 04:46:18 2016 done: Thu Nov 3 04:46:20 2016
Total Scan time: 19.480 Total Display time: 0.830
Function used was FASTA [36.3.4 Apr, 2011]