FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1052, 1455 aa 1>>>pF1KSDA1052 1455 - 1455 aa - 1455 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.3687+/-0.000499; mu= -23.4010+/- 0.031 mean_var=673.2301+/-143.016, 0's: 0 Z-trim(122.9): 309 B-trim: 0 in 0/58 Lambda= 0.049430 statistics sampled from 41311 (41663) to 41311 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.488), width: 16 Scan time: 19.480 The best scores are: opt bits E(85289) NP_001258862 (OMIM: 614845,614848) centrosomal pro (1455) 9430 689.0 6.8e-197 XP_005271514 (OMIM: 614845,614848) PREDICTED: cent (1455) 9430 689.0 6.8e-197 XP_005271513 (OMIM: 614845,614848) PREDICTED: cent (1460) 9360 684.1 2.2e-195 NP_055771 (OMIM: 614845,614848) centrosomal protei (1460) 9360 684.1 2.2e-195 XP_006718851 (OMIM: 614845,614848) PREDICTED: cent (2025) 8496 622.6 9.8e-177 XP_005271510 (OMIM: 614845,614848) PREDICTED: cent (2022) 8455 619.6 7.5e-176 XP_006718857 (OMIM: 614845,614848) PREDICTED: cent (1434) 7669 563.5 4.3e-159 XP_016872861 (OMIM: 614845,614848) PREDICTED: cent (1996) 7669 563.6 5.5e-159 XP_016872871 (OMIM: 614845,614848) PREDICTED: cent (1454) 6334 468.3 2e-130 XP_016872870 (OMIM: 614845,614848) PREDICTED: cent (1454) 6334 468.3 2e-130 XP_016872858 (OMIM: 614845,614848) PREDICTED: cent (2034) 6329 468.0 3.3e-130 XP_016872859 (OMIM: 614845,614848) PREDICTED: cent (2033) 6312 466.8 7.6e-130 XP_016872874 (OMIM: 614845,614848) PREDICTED: cent (1367) 6300 465.8 1e-129 XP_016872872 (OMIM: 614845,614848) PREDICTED: cent (1434) 6300 465.8 1e-129 XP_016872873 (OMIM: 614845,614848) PREDICTED: cent (1434) 6300 465.8 1e-129 XP_016872860 (OMIM: 614845,614848) PREDICTED: cent (2016) 6305 466.3 1.1e-129 XP_016872869 (OMIM: 614845,614848) PREDICTED: cent (1480) 6300 465.8 1.1e-129 XP_016872868 (OMIM: 614845,614848) PREDICTED: cent (1480) 6300 465.8 1.1e-129 XP_016872866 (OMIM: 614845,614848) PREDICTED: cent (1960) 6300 465.9 1.3e-129 XP_016872864 (OMIM: 614845,614848) PREDICTED: cent (1996) 6300 465.9 1.3e-129 XP_016872863 (OMIM: 614845,614848) PREDICTED: cent (1996) 6300 465.9 1.3e-129 XP_016872862 (OMIM: 614845,614848) PREDICTED: cent (1996) 6300 465.9 1.3e-129 XP_016872855 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129 XP_011540976 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129 XP_016872854 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129 XP_016872856 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129 XP_016872853 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129 XP_016872857 (OMIM: 614845,614848) PREDICTED: cent (2041) 6283 464.7 3.2e-129 XP_016872865 (OMIM: 614845,614848) PREDICTED: cent (1993) 5665 420.7 5.8e-116 XP_016872875 (OMIM: 614845,614848) PREDICTED: cent (1339) 5643 419.0 1.3e-115 XP_016872867 (OMIM: 614845,614848) PREDICTED: cent (1923) 5133 382.7 1.5e-104 XP_011540992 (OMIM: 614845,614848) PREDICTED: cent ( 792) 968 85.4 1.9e-15 NP_115627 (OMIM: 611205) coiled-coil domain-contai (1476) 407 45.6 0.0034 XP_006718582 (OMIM: 611205) PREDICTED: coiled-coil (1560) 407 45.6 0.0036 XP_005245422 (OMIM: 609473) PREDICTED: cingulin is (1203) 403 45.2 0.0036 NP_065821 (OMIM: 609473) cingulin [Homo sapiens] (1203) 403 45.2 0.0036 NP_958783 (OMIM: 131950,226670,226730,601282,61213 (4515) 403 45.7 0.0098 XP_005251041 (OMIM: 131950,226670,226730,601282,61 (4520) 403 45.7 0.0098 XP_005251040 (OMIM: 131950,226670,226730,601282,61 (4524) 403 45.7 0.0098 XP_011515433 (OMIM: 131950,226670,226730,601282,61 (4524) 403 45.7 0.0098 NP_958781 (OMIM: 131950,226670,226730,601282,61213 (4525) 403 45.7 0.0098 XP_006716652 (OMIM: 131950,226670,226730,601282,61 (4529) 403 45.7 0.0098 XP_006716653 (OMIM: 131950,226670,226730,601282,61 (4529) 403 45.7 0.0098 XP_005251039 (OMIM: 131950,226670,226730,601282,61 (4530) 403 45.7 0.0098 NP_958780 (OMIM: 131950,226670,226730,601282,61213 (4533) 403 45.7 0.0098 XP_005251038 (OMIM: 131950,226670,226730,601282,61 (4538) 403 45.7 0.0099 NP_958784 (OMIM: 131950,226670,226730,601282,61213 (4547) 403 45.7 0.0099 NP_958786 (OMIM: 131950,226670,226730,601282,61213 (4547) 403 45.7 0.0099 NP_958785 (OMIM: 131950,226670,226730,601282,61213 (4551) 403 45.7 0.0099 XP_005251037 (OMIM: 131950,226670,226730,601282,61 (4552) 403 45.7 0.0099 >>NP_001258862 (OMIM: 614845,614848) centrosomal protein (1455 aa) initn: 9430 init1: 9430 opt: 9430 Z-score: 3655.8 bits: 689.0 E(85289): 6.8e-197 Smith-Waterman score: 9430; 100.0% identity (100.0% similar) in 1455 aa overlap (1-1455:1-1455) 10 20 30 40 50 60 pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL 1390 1400 1410 1420 1430 1440 1450 pF1KSD QLGLDEHNRVKVYRF ::::::::::::::: NP_001 QLGLDEHNRVKVYRF 1450 >>XP_005271514 (OMIM: 614845,614848) PREDICTED: centroso (1455 aa) initn: 9430 init1: 9430 opt: 9430 Z-score: 3655.8 bits: 689.0 E(85289): 6.8e-197 Smith-Waterman score: 9430; 100.0% identity (100.0% similar) in 1455 aa overlap (1-1455:1-1455) 10 20 30 40 50 60 pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KSD HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KSD SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KSD SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL 1390 1400 1410 1420 1430 1440 1450 pF1KSD QLGLDEHNRVKVYRF ::::::::::::::: XP_005 QLGLDEHNRVKVYRF 1450 >>XP_005271513 (OMIM: 614845,614848) PREDICTED: centroso (1460 aa) initn: 6313 init1: 4930 opt: 9360 Z-score: 3628.8 bits: 684.1 E(85289): 2.2e-195 Smith-Waterman score: 9360; 99.2% identity (99.2% similar) in 1463 aa overlap (1-1455:1-1460) 10 20 30 40 50 60 pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_005 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER---LSPPLPH 430 440 450 460 470 490 500 510 520 530 540 pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE 480 490 500 510 520 530 550 560 570 580 590 600 pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE 540 550 560 570 580 590 610 620 630 640 650 660 pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE 600 610 620 630 640 650 670 680 690 700 710 720 pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK 660 670 680 690 700 710 730 740 750 760 770 780 pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR 780 790 800 810 820 830 850 860 870 880 890 900 pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER 840 850 860 870 880 890 910 920 930 940 950 960 pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPH--------LDSTPSLT :::::::::::::::::::::::::::::::::::::::::::: .::::::: XP_005 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLT 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KSD SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KSD LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KSD LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK 1380 1390 1400 1410 1420 1430 1440 1450 pF1KSD PKATLSLLQLGLDEHNRVKVYRF ::::::::::::::::::::::: XP_005 PKATLSLLQLGLDEHNRVKVYRF 1440 1450 1460 >>NP_055771 (OMIM: 614845,614848) centrosomal protein of (1460 aa) initn: 6313 init1: 4930 opt: 9360 Z-score: 3628.8 bits: 684.1 E(85289): 2.2e-195 Smith-Waterman score: 9360; 99.2% identity (99.2% similar) in 1463 aa overlap (1-1455:1-1460) 10 20 30 40 50 60 pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: NP_055 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER---LSPPLPH 430 440 450 460 470 490 500 510 520 530 540 pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE 480 490 500 510 520 530 550 560 570 580 590 600 pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE 540 550 560 570 580 590 610 620 630 640 650 660 pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE 600 610 620 630 640 650 670 680 690 700 710 720 pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK 660 670 680 690 700 710 730 740 750 760 770 780 pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR 780 790 800 810 820 830 850 860 870 880 890 900 pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER 840 850 860 870 880 890 910 920 930 940 950 960 pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE 1020 1030 1040 1050 1060 1070 1090 1100 1110 1120 1130 1140 pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH 1080 1090 1100 1110 1120 1130 1150 1160 1170 1180 1190 1200 pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE 1140 1150 1160 1170 1180 1190 1210 1220 1230 1240 1250 pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPH--------LDSTPSLT :::::::::::::::::::::::::::::::::::::::::::: .::::::: NP_055 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLT 1200 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KSD SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 pF1KSD LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KSD LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK 1380 1390 1400 1410 1420 1430 1440 1450 pF1KSD PKATLSLLQLGLDEHNRVKVYRF ::::::::::::::::::::::: NP_055 PKATLSLLQLGLDEHNRVKVYRF 1440 1450 1460 >>XP_006718851 (OMIM: 614845,614848) PREDICTED: centroso (2025 aa) initn: 9399 init1: 7125 opt: 8496 Z-score: 3293.9 bits: 622.6 E(85289): 9.8e-177 Smith-Waterman score: 8496; 99.3% identity (99.4% similar) in 1332 aa overlap (132-1455:694-2025) 110 120 130 140 150 160 pF1KSD KLSTSGAIKKKKKKKEKKDKKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSAL :::::::::::::::::::::::::::::: XP_006 SSSTLRQGLVQQSSSRGLTTEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSAL 670 680 690 700 710 720 170 180 190 200 210 220 pF1KSD RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE 730 740 750 760 770 780 230 240 250 260 270 280 pF1KSD DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP 790 800 810 820 830 840 290 300 310 320 330 340 pF1KSD CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK 850 860 870 880 890 900 350 360 370 380 390 400 pF1KSD ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI 910 920 930 940 950 960 410 420 430 440 450 460 pF1KSD ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS 970 980 990 1000 1010 1020 470 480 490 500 510 520 pF1KSD KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL 1030 1040 1050 1060 1070 1080 530 540 550 560 570 580 pF1KSD SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST 1090 1100 1110 1120 1130 1140 590 600 610 620 630 640 pF1KSD EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ 1150 1160 1170 1180 1190 1200 650 660 670 680 690 700 pF1KSD QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK 1210 1220 1230 1240 1250 1260 710 720 730 740 750 760 pF1KSD LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE 1270 1280 1290 1300 1310 1320 770 780 790 800 810 820 pF1KSD RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV 1330 1340 1350 1360 1370 1380 830 840 850 860 870 880 pF1KSD HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA 1390 1400 1410 1420 1430 1440 890 900 910 920 930 940 pF1KSD ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV 1450 1460 1470 1480 1490 1500 950 960 970 980 990 1000 pF1KSD KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR 1510 1520 1530 1540 1550 1560 1010 1020 1030 1040 1050 1060 pF1KSD EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE 1570 1580 1590 1600 1610 1620 1070 1080 1090 1100 1110 1120 pF1KSD PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV 1630 1640 1650 1660 1670 1680 1130 1140 1150 1160 1170 1180 pF1KSD QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA 1690 1700 1710 1720 1730 1740 1190 1200 1210 1220 1230 1240 pF1KSD MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS 1750 1760 1770 1780 1790 1800 1250 1260 1270 1280 1290 pF1KSD PPH--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP ::: .:::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP 1810 1820 1830 1840 1850 1860 1300 1310 1320 1330 1340 1350 pF1KSD AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE 1870 1880 1890 1900 1910 1920 1360 1370 1380 1390 1400 1410 pF1KSD KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR 1930 1940 1950 1960 1970 1980 1420 1430 1440 1450 pF1KSD WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF :::::::::::::::::::::::::::::::::::::::::: XP_006 WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF 1990 2000 2010 2020 >-- initn: 1003 init1: 905 opt: 976 Z-score: 395.7 bits: 86.3 E(85289): 2.7e-15 Smith-Waterman score: 1001; 38.0% identity (56.4% similar) in 731 aa overlap (1-626:1-693) 10 20 30 40 50 60 pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD 70 80 90 100 110 120 130 140 150 pF1KSD KKDRDPPKSSL------------ALGSSLAPVHVPLGGLAPL---------------RG- ::::::::::: .. ::.: .: ::: : .: XP_006 KKDRDPPKSSLETQPEEGLLPPSSFLCSLSPPSAP--GLADLDLDQEMQAISEGSYNKGK 130 140 150 160 170 160 170 180 190 pF1KSD ----LVDTP---PSAL-RGSQSVSLG--SSVES---------GR---QLGELMLPSQGLK : ::: .:: : : .: : :.... :: : . . .:::. XP_006 SPGMLGDTPWRFMGALPRKLQPLSKGQPSQIHQVFADMEKILGRAPAQCRRELGDQQGLE 180 190 200 210 220 230 200 210 220 230 pF1KSD T--SAYTKGLLGSIYEDKTALSL------LGL------GEETNEEDEEESDNQ-SVHSS- .: : :: . : . :: : : .: :: :: ::::. XP_006 KLQKATEKIYLGFSDPETEELEMRSRQQKLGTPAPQNTGLLQNMQDVVESRNQASVHSKL 240 250 260 270 280 290 240 250 260 270 280 pF1KSD SEPLRNLHL-------DIGAL-----GGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPC :: ...: : ... : ::: . . . :.:::. ::.: ..: : XP_006 SEAIKGLPLKGEQHSHSLAKLSPTGPGGD-KGQSPIPMSSPEEEP--SLSSCSSGHMLPA 300 310 320 330 340 350 290 300 310 320 pF1KSD KPS------SPGADSSLSSAVGKGRQ-GSGAR----PGLPEKEENE---KSEPKICRNLV . : :: : : ... :.: . ::: : ::: .. .. :. : :. XP_006 RKSKLLLDSSPTEDLSWQGVPGEGGSIGSGRRRREPPGLWMEQVSKLVNKDIPGSCK--- 360 370 380 390 400 410 330 340 350 360 370 380 pF1KSD TPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEL-- ...:. : :: .. :. . : . : :..: . : .:. : : XP_006 --ETEPSDPEALGASAEDLPQGLLLIPPE-TLASEPAQNPLLGRAPEEPPASEKRQALGS 420 430 440 450 460 390 400 410 420 430 440 pF1KSD -EISEHMKEPQLSD-SIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPL :. . ..:.:: .. :. .: . : .. :: :::: . . : XP_006 AELPYKDQKPSLSGPDLESSSSSSSN------SNLASHLG-----SPVLDEV---NNFPW 470 480 490 500 510 450 460 470 480 490 500 pF1KSD GIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPL-PHEERAQSPPRSLATEEEPPQGPEG ... :. ...: ......:: : ...:: : :: . ::: . . :. : XP_006 NLQ----SSRGSEEGMAQSDSGL--RDQHFSPFLDPHMSHMQSPDEEQSESEDYS---ED 520 530 540 550 560 510 520 530 540 550 560 pF1KSD QPEWKEAEELGEDSAASLSLQLSLQREQAP---SPPAACEKGKEQHSQAEELGPGQEEAE : ... .. . : .: : . .. : : ..: . :. .. : :..:: XP_006 QRFYQHILQMVKISRWPEGLGLPESMQDMPCRHSASTVCCMAAESSRMSSE---GEHEAI 570 580 590 600 610 620 570 580 590 600 610 pF1KSD DPEEKVA--VSPTPPV--SPEVRSTEPVAPPEQLSEAALKAMEEAVAQ-VLEQDQRHLLE :. . .: : . :. . : : : ..: .. .. : ...:.. . : XP_006 RVMERDSRFLSWEPELLEHPQEVALAP-AWQEASQQAHFQPSSSTLRQGLVQQSSSRGLT 630 640 650 660 670 680 620 630 640 650 660 670 pF1KSD SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW .. :::.: . XP_006 TEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG 690 700 710 720 730 740 >>XP_005271510 (OMIM: 614845,614848) PREDICTED: centroso (2022 aa) initn: 7204 init1: 4930 opt: 8455 Z-score: 3278.1 bits: 619.6 E(85289): 7.5e-176 Smith-Waterman score: 8455; 99.1% identity (99.2% similar) in 1332 aa overlap (132-1455:694-2022) 110 120 130 140 150 160 pF1KSD KLSTSGAIKKKKKKKEKKDKKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSAL :::::::::::::::::::::::::::::: XP_005 SSSTLRQGLVQQSSSRGLTTEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSAL 670 680 690 700 710 720 170 180 190 200 210 220 pF1KSD RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE 730 740 750 760 770 780 230 240 250 260 270 280 pF1KSD DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP 790 800 810 820 830 840 290 300 310 320 330 340 pF1KSD CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK 850 860 870 880 890 900 350 360 370 380 390 400 pF1KSD ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI 910 920 930 940 950 960 410 420 430 440 450 460 pF1KSD ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS 970 980 990 1000 1010 1020 470 480 490 500 510 520 pF1KSD KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQSKGLEE---RLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL 1030 1040 1050 1060 1070 1080 530 540 550 560 570 580 pF1KSD SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST 1090 1100 1110 1120 1130 1140 590 600 610 620 630 640 pF1KSD EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ 1150 1160 1170 1180 1190 1200 650 660 670 680 690 700 pF1KSD QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK 1210 1220 1230 1240 1250 1260 710 720 730 740 750 760 pF1KSD LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE 1270 1280 1290 1300 1310 1320 770 780 790 800 810 820 pF1KSD RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV 1330 1340 1350 1360 1370 1380 830 840 850 860 870 880 pF1KSD HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA 1390 1400 1410 1420 1430 1440 890 900 910 920 930 940 pF1KSD ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV 1450 1460 1470 1480 1490 1500 950 960 970 980 990 1000 pF1KSD KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR 1510 1520 1530 1540 1550 1560 1010 1020 1030 1040 1050 1060 pF1KSD EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE 1570 1580 1590 1600 1610 1620 1070 1080 1090 1100 1110 1120 pF1KSD PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV 1630 1640 1650 1660 1670 1680 1130 1140 1150 1160 1170 1180 pF1KSD QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA 1690 1700 1710 1720 1730 1740 1190 1200 1210 1220 1230 1240 pF1KSD MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS 1750 1760 1770 1780 1790 1800 1250 1260 1270 1280 1290 pF1KSD PPH--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP ::: .:::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP 1810 1820 1830 1840 1850 1860 1300 1310 1320 1330 1340 1350 pF1KSD AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE 1870 1880 1890 1900 1910 1920 1360 1370 1380 1390 1400 1410 pF1KSD KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR 1930 1940 1950 1960 1970 1980 1420 1430 1440 1450 pF1KSD WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF :::::::::::::::::::::::::::::::::::::::::: XP_005 WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF 1990 2000 2010 2020 >-- initn: 1003 init1: 905 opt: 976 Z-score: 395.7 bits: 86.3 E(85289): 2.7e-15 Smith-Waterman score: 1001; 38.0% identity (56.4% similar) in 731 aa overlap (1-626:1-693) 10 20 30 40 50 60 pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD 70 80 90 100 110 120 130 140 150 pF1KSD KKDRDPPKSSL------------ALGSSLAPVHVPLGGLAPL---------------RG- ::::::::::: .. ::.: .: ::: : .: XP_005 KKDRDPPKSSLETQPEEGLLPPSSFLCSLSPPSAP--GLADLDLDQEMQAISEGSYNKGK 130 140 150 160 170 160 170 180 190 pF1KSD ----LVDTP---PSAL-RGSQSVSLG--SSVES---------GR---QLGELMLPSQGLK : ::: .:: : : .: : :.... :: : . . .:::. XP_005 SPGMLGDTPWRFMGALPRKLQPLSKGQPSQIHQVFADMEKILGRAPAQCRRELGDQQGLE 180 190 200 210 220 230 200 210 220 230 pF1KSD T--SAYTKGLLGSIYEDKTALSL------LGL------GEETNEEDEEESDNQ-SVHSS- .: : :: . : . :: : : .: :: :: ::::. XP_005 KLQKATEKIYLGFSDPETEELEMRSRQQKLGTPAPQNTGLLQNMQDVVESRNQASVHSKL 240 250 260 270 280 290 240 250 260 270 280 pF1KSD SEPLRNLHL-------DIGAL-----GGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPC :: ...: : ... : ::: . . . :.:::. ::.: ..: : XP_005 SEAIKGLPLKGEQHSHSLAKLSPTGPGGD-KGQSPIPMSSPEEEP--SLSSCSSGHMLPA 300 310 320 330 340 350 290 300 310 320 pF1KSD KPS------SPGADSSLSSAVGKGRQ-GSGAR----PGLPEKEENE---KSEPKICRNLV . : :: : : ... :.: . ::: : ::: .. .. :. : :. XP_005 RKSKLLLDSSPTEDLSWQGVPGEGGSIGSGRRRREPPGLWMEQVSKLVNKDIPGSCK--- 360 370 380 390 400 410 330 340 350 360 370 380 pF1KSD TPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEL-- ...:. : :: .. :. . : . : :..: . : .:. : : XP_005 --ETEPSDPEALGASAEDLPQGLLLIPPE-TLASEPAQNPLLGRAPEEPPASEKRQALGS 420 430 440 450 460 390 400 410 420 430 440 pF1KSD -EISEHMKEPQLSD-SIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPL :. . ..:.:: .. :. .: . : .. :: :::: . . : XP_005 AELPYKDQKPSLSGPDLESSSSSSSN------SNLASHLG-----SPVLDEV---NNFPW 470 480 490 500 510 450 460 470 480 490 500 pF1KSD GIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPL-PHEERAQSPPRSLATEEEPPQGPEG ... :. ...: ......:: : ...:: : :: . ::: . . :. : XP_005 NLQ----SSRGSEEGMAQSDSGL--RDQHFSPFLDPHMSHMQSPDEEQSESEDYS---ED 520 530 540 550 560 510 520 530 540 550 560 pF1KSD QPEWKEAEELGEDSAASLSLQLSLQREQAP---SPPAACEKGKEQHSQAEELGPGQEEAE : ... .. . : .: : . .. : : ..: . :. .. : :..:: XP_005 QRFYQHILQMVKISRWPEGLGLPESMQDMPCRHSASTVCCMAAESSRMSSE---GEHEAI 570 580 590 600 610 620 570 580 590 600 610 pF1KSD DPEEKVA--VSPTPPV--SPEVRSTEPVAPPEQLSEAALKAMEEAVAQ-VLEQDQRHLLE :. . .: : . :. . : : : ..: .. .. : ...:.. . : XP_005 RVMERDSRFLSWEPELLEHPQEVALAP-AWQEASQQAHFQPSSSTLRQGLVQQSSSRGLT 630 640 650 660 670 680 620 630 640 650 660 670 pF1KSD SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW .. :::.: . XP_005 TEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG 690 700 710 720 730 740 >>XP_006718857 (OMIM: 614845,614848) PREDICTED: centroso (1434 aa) initn: 7831 init1: 4930 opt: 7669 Z-score: 2977.2 bits: 563.5 E(85289): 4.3e-159 Smith-Waterman score: 9125; 97.4% identity (97.5% similar) in 1463 aa overlap (1-1455:1-1434) 10 20 30 40 50 60 pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQ----------- 190 200 210 220 250 260 270 280 290 300 pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG ::::::::::::::::::::::::::::::::::::::::::::: XP_006 ---------------ESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG 230 240 250 260 270 310 320 330 340 350 360 pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR 280 290 300 310 320 330 370 380 390 400 410 420 pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS 340 350 360 370 380 390 430 440 450 460 470 480 pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH :::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_006 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER---LSPPLPH 400 410 420 430 440 450 490 500 510 520 530 540 pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE 460 470 480 490 500 510 550 560 570 580 590 600 pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE 520 530 540 550 560 570 610 620 630 640 650 660 pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE 580 590 600 610 620 630 670 680 690 700 710 720 pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK 640 650 660 670 680 690 730 740 750 760 770 780 pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL 700 710 720 730 740 750 790 800 810 820 830 840 pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR 760 770 780 790 800 810 850 860 870 880 890 900 pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER 820 830 840 850 860 870 910 920 930 940 950 960 pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ 880 890 900 910 920 930 970 980 990 1000 1010 1020 pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL 940 950 960 970 980 990 1030 1040 1050 1060 1070 1080 pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE 1000 1010 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPH--------LDSTPSLT :::::::::::::::::::::::::::::::::::::::::::: .::::::: XP_006 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLT 1180 1190 1200 1210 1220 1230 1260 1270 1280 1290 1300 1310 pF1KSD SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS 1240 1250 1260 1270 1280 1290 1320 1330 1340 1350 1360 1370 pF1KSD LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP 1300 1310 1320 1330 1340 1350 1380 1390 1400 1410 1420 1430 pF1KSD LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK 1360 1370 1380 1390 1400 1410 1440 1450 pF1KSD PKATLSLLQLGLDEHNRVKVYRF ::::::::::::::::::::::: XP_006 PKATLSLLQLGLDEHNRVKVYRF 1420 1430 >>XP_016872861 (OMIM: 614845,614848) PREDICTED: centroso (1996 aa) initn: 7817 init1: 4930 opt: 7669 Z-score: 2975.3 bits: 563.6 E(85289): 5.5e-159 Smith-Waterman score: 8220; 97.1% identity (97.2% similar) in 1332 aa overlap (132-1455:694-1996) 110 120 130 140 150 160 pF1KSD KLSTSGAIKKKKKKKEKKDKKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSAL :::::::::::::::::::::::::::::: XP_016 SSSTLRQGLVQQSSSRGLTTEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSAL 670 680 690 700 710 720 170 180 190 200 210 220 pF1KSD RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE 730 740 750 760 770 780 230 240 250 260 270 280 pF1KSD DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP :::::::: :::::::::::::::::::::::::: XP_016 DEEESDNQ--------------------------ESLRTSQPEEKKDVSLDSDAAGPPTP 790 800 810 290 300 310 320 330 340 pF1KSD CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK 820 830 840 850 860 870 350 360 370 380 390 400 pF1KSD ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI 880 890 900 910 920 930 410 420 430 440 450 460 pF1KSD ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS 940 950 960 970 980 990 470 480 490 500 510 520 pF1KSD KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQSKGLEE---RLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL 1000 1010 1020 1030 1040 1050 530 540 550 560 570 580 pF1KSD SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST 1060 1070 1080 1090 1100 1110 590 600 610 620 630 640 pF1KSD EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ 1120 1130 1140 1150 1160 1170 650 660 670 680 690 700 pF1KSD QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK 1180 1190 1200 1210 1220 1230 710 720 730 740 750 760 pF1KSD LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE 1240 1250 1260 1270 1280 1290 770 780 790 800 810 820 pF1KSD RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV 1300 1310 1320 1330 1340 1350 830 840 850 860 870 880 pF1KSD HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA 1360 1370 1380 1390 1400 1410 890 900 910 920 930 940 pF1KSD ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV 1420 1430 1440 1450 1460 1470 950 960 970 980 990 1000 pF1KSD KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR 1480 1490 1500 1510 1520 1530 1010 1020 1030 1040 1050 1060 pF1KSD EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE 1540 1550 1560 1570 1580 1590 1070 1080 1090 1100 1110 1120 pF1KSD PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV 1600 1610 1620 1630 1640 1650 1130 1140 1150 1160 1170 1180 pF1KSD QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA 1660 1670 1680 1690 1700 1710 1190 1200 1210 1220 1230 1240 pF1KSD MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS 1720 1730 1740 1750 1760 1770 1250 1260 1270 1280 1290 pF1KSD PPH--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP ::: .:::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP 1780 1790 1800 1810 1820 1830 1300 1310 1320 1330 1340 1350 pF1KSD AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE 1840 1850 1860 1870 1880 1890 1360 1370 1380 1390 1400 1410 pF1KSD KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR 1900 1910 1920 1930 1940 1950 1420 1430 1440 1450 pF1KSD WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF :::::::::::::::::::::::::::::::::::::::::: XP_016 WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF 1960 1970 1980 1990 >-- initn: 1003 init1: 905 opt: 976 Z-score: 395.8 bits: 86.3 E(85289): 2.6e-15 Smith-Waterman score: 1001; 38.0% identity (56.4% similar) in 731 aa overlap (1-626:1-693) 10 20 30 40 50 60 pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD 70 80 90 100 110 120 130 140 150 pF1KSD KKDRDPPKSSL------------ALGSSLAPVHVPLGGLAPL---------------RG- ::::::::::: .. ::.: .: ::: : .: XP_016 KKDRDPPKSSLETQPEEGLLPPSSFLCSLSPPSAP--GLADLDLDQEMQAISEGSYNKGK 130 140 150 160 170 160 170 180 190 pF1KSD ----LVDTP---PSAL-RGSQSVSLG--SSVES---------GR---QLGELMLPSQGLK : ::: .:: : : .: : :.... :: : . . .:::. XP_016 SPGMLGDTPWRFMGALPRKLQPLSKGQPSQIHQVFADMEKILGRAPAQCRRELGDQQGLE 180 190 200 210 220 230 200 210 220 230 pF1KSD T--SAYTKGLLGSIYEDKTALSL------LGL------GEETNEEDEEESDNQ-SVHSS- .: : :: . : . :: : : .: :: :: ::::. XP_016 KLQKATEKIYLGFSDPETEELEMRSRQQKLGTPAPQNTGLLQNMQDVVESRNQASVHSKL 240 250 260 270 280 290 240 250 260 270 280 pF1KSD SEPLRNLHL-------DIGAL-----GGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPC :: ...: : ... : ::: . . . :.:::. ::.: ..: : XP_016 SEAIKGLPLKGEQHSHSLAKLSPTGPGGD-KGQSPIPMSSPEEEP--SLSSCSSGHMLPA 300 310 320 330 340 350 290 300 310 320 pF1KSD KPS------SPGADSSLSSAVGKGRQ-GSGAR----PGLPEKEENE---KSEPKICRNLV . : :: : : ... :.: . ::: : ::: .. .. :. : :. XP_016 RKSKLLLDSSPTEDLSWQGVPGEGGSIGSGRRRREPPGLWMEQVSKLVNKDIPGSCK--- 360 370 380 390 400 410 330 340 350 360 370 380 pF1KSD TPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEL-- ...:. : :: .. :. . : . : :..: . : .:. : : XP_016 --ETEPSDPEALGASAEDLPQGLLLIPPE-TLASEPAQNPLLGRAPEEPPASEKRQALGS 420 430 440 450 460 390 400 410 420 430 440 pF1KSD -EISEHMKEPQLSD-SIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPL :. . ..:.:: .. :. .: . : .. :: :::: . . : XP_016 AELPYKDQKPSLSGPDLESSSSSSSN------SNLASHLG-----SPVLDEV---NNFPW 470 480 490 500 510 450 460 470 480 490 500 pF1KSD GIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPL-PHEERAQSPPRSLATEEEPPQGPEG ... :. ...: ......:: : ...:: : :: . ::: . . :. : XP_016 NLQ----SSRGSEEGMAQSDSGL--RDQHFSPFLDPHMSHMQSPDEEQSESEDYS---ED 520 530 540 550 560 510 520 530 540 550 560 pF1KSD QPEWKEAEELGEDSAASLSLQLSLQREQAP---SPPAACEKGKEQHSQAEELGPGQEEAE : ... .. . : .: : . .. : : ..: . :. .. : :..:: XP_016 QRFYQHILQMVKISRWPEGLGLPESMQDMPCRHSASTVCCMAAESSRMSSE---GEHEAI 570 580 590 600 610 620 570 580 590 600 610 pF1KSD DPEEKVA--VSPTPPV--SPEVRSTEPVAPPEQLSEAALKAMEEAVAQ-VLEQDQRHLLE :. . .: : . :. . : : : ..: .. .. : ...:.. . : XP_016 RVMERDSRFLSWEPELLEHPQEVALAP-AWQEASQQAHFQPSSSTLRQGLVQQSSSRGLT 630 640 650 660 670 680 620 630 640 650 660 670 pF1KSD SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW .. :::.: . XP_016 TEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG 690 700 710 720 730 740 >>XP_016872871 (OMIM: 614845,614848) PREDICTED: centroso (1454 aa) initn: 7810 init1: 4909 opt: 6334 Z-score: 2462.6 bits: 468.3 E(85289): 2e-130 Smith-Waterman score: 9093; 96.3% identity (96.4% similar) in 1480 aa overlap (1-1455:1-1454) 10 20 30 40 50 60 pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQ----------- 190 200 210 220 250 260 270 280 290 300 pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG ::::::::::::::::::::::::::::::::::::::::::::: XP_016 ---------------ESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG 230 240 250 260 270 310 320 330 340 350 360 pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR 280 290 300 310 320 330 370 380 390 400 410 420 pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS 340 350 360 370 380 390 430 440 450 460 470 pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER---------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEESSLPALQMEGP 400 410 420 430 440 450 480 490 500 510 520 pF1KSD -------YHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSAALPGLTRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL 460 470 480 490 500 510 530 540 550 560 570 580 pF1KSD QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP 520 530 540 550 560 570 590 600 610 620 630 640 pF1KSD VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK 580 590 600 610 620 630 650 660 670 680 690 700 pF1KSD EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR 640 650 660 670 680 690 710 720 730 740 750 760 pF1KSD EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK 700 710 720 730 740 750 770 780 790 800 810 820 pF1KSD EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ 760 770 780 790 800 810 830 840 850 860 870 880 pF1KSD KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL 820 830 840 850 860 870 890 900 910 920 930 940 pF1KSD LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA 880 890 900 910 920 930 950 960 970 980 990 1000 pF1KSD RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI 940 950 960 970 980 990 1010 1020 1030 1040 1050 1060 pF1KSD LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD 1000 1010 1020 1030 1040 1050 1070 1080 1090 1100 1110 1120 pF1KSD LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ 1060 1070 1080 1090 1100 1110 1130 1140 1150 1160 1170 1180 pF1KSD TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR 1120 1130 1140 1150 1160 1170 1190 1200 1210 1220 1230 1240 pF1KSD KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP 1180 1190 1200 1210 1220 1230 1250 1260 1270 1280 1290 pF1KSD H--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ : .:::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ 1240 1250 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW 1300 1310 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 pF1KSD RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL 1360 1370 1380 1390 1400 1410 1420 1430 1440 1450 pF1KSD ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF :::::::::::::::::::::::::::::::::::::::: XP_016 ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF 1420 1430 1440 1450 >>XP_016872870 (OMIM: 614845,614848) PREDICTED: centroso (1454 aa) initn: 7810 init1: 4909 opt: 6334 Z-score: 2462.6 bits: 468.3 E(85289): 2e-130 Smith-Waterman score: 9093; 96.3% identity (96.4% similar) in 1480 aa overlap (1-1455:1-1454) 10 20 30 40 50 60 pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQ----------- 190 200 210 220 250 260 270 280 290 300 pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG ::::::::::::::::::::::::::::::::::::::::::::: XP_016 ---------------ESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG 230 240 250 260 270 310 320 330 340 350 360 pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR 280 290 300 310 320 330 370 380 390 400 410 420 pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS 340 350 360 370 380 390 430 440 450 460 470 pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER---------- ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEESSLPALQMEGP 400 410 420 430 440 450 480 490 500 510 520 pF1KSD -------YHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSAALPGLTRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL 460 470 480 490 500 510 530 540 550 560 570 580 pF1KSD QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP 520 530 540 550 560 570 590 600 610 620 630 640 pF1KSD VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK 580 590 600 610 620 630 650 660 670 680 690 700 pF1KSD EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR 640 650 660 670 680 690 710 720 730 740 750 760 pF1KSD EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK 700 710 720 730 740 750 770 780 790 800 810 820 pF1KSD EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ 760 770 780 790 800 810 830 840 850 860 870 880 pF1KSD KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL 820 830 840 850 860 870 890 900 910 920 930 940 pF1KSD LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA 880 890 900 910 920 930 950 960 970 980 990 1000 pF1KSD RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI 940 950 960 970 980 990 1010 1020 1030 1040 1050 1060 pF1KSD LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD 1000 1010 1020 1030 1040 1050 1070 1080 1090 1100 1110 1120 pF1KSD LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ 1060 1070 1080 1090 1100 1110 1130 1140 1150 1160 1170 1180 pF1KSD TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR 1120 1130 1140 1150 1160 1170 1190 1200 1210 1220 1230 1240 pF1KSD KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP 1180 1190 1200 1210 1220 1230 1250 1260 1270 1280 1290 pF1KSD H--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ : .:::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ 1240 1250 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KSD LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW 1300 1310 1320 1330 1340 1350 1360 1370 1380 1390 1400 1410 pF1KSD RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL 1360 1370 1380 1390 1400 1410 1420 1430 1440 1450 pF1KSD ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF :::::::::::::::::::::::::::::::::::::::: XP_016 ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF 1420 1430 1440 1450 1455 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:46:18 2016 done: Thu Nov 3 04:46:20 2016 Total Scan time: 19.480 Total Display time: 0.830 Function used was FASTA [36.3.4 Apr, 2011]