Result of FASTA (omim) for pF1KSDA1052
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1052, 1455 aa
  1>>>pF1KSDA1052 1455 - 1455 aa - 1455 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 15.3687+/-0.000499; mu= -23.4010+/- 0.031
 mean_var=673.2301+/-143.016, 0's: 0 Z-trim(122.9): 309  B-trim: 0 in 0/58
 Lambda= 0.049430
 statistics sampled from 41311 (41663) to 41311 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.488), width:  16
 Scan time: 19.480

The best scores are:                                      opt bits E(85289)
NP_001258862 (OMIM: 614845,614848) centrosomal pro (1455) 9430 689.0 6.8e-197
XP_005271514 (OMIM: 614845,614848) PREDICTED: cent (1455) 9430 689.0 6.8e-197
XP_005271513 (OMIM: 614845,614848) PREDICTED: cent (1460) 9360 684.1 2.2e-195
NP_055771 (OMIM: 614845,614848) centrosomal protei (1460) 9360 684.1 2.2e-195
XP_006718851 (OMIM: 614845,614848) PREDICTED: cent (2025) 8496 622.6 9.8e-177
XP_005271510 (OMIM: 614845,614848) PREDICTED: cent (2022) 8455 619.6 7.5e-176
XP_006718857 (OMIM: 614845,614848) PREDICTED: cent (1434) 7669 563.5 4.3e-159
XP_016872861 (OMIM: 614845,614848) PREDICTED: cent (1996) 7669 563.6 5.5e-159
XP_016872871 (OMIM: 614845,614848) PREDICTED: cent (1454) 6334 468.3  2e-130
XP_016872870 (OMIM: 614845,614848) PREDICTED: cent (1454) 6334 468.3  2e-130
XP_016872858 (OMIM: 614845,614848) PREDICTED: cent (2034) 6329 468.0 3.3e-130
XP_016872859 (OMIM: 614845,614848) PREDICTED: cent (2033) 6312 466.8 7.6e-130
XP_016872874 (OMIM: 614845,614848) PREDICTED: cent (1367) 6300 465.8  1e-129
XP_016872872 (OMIM: 614845,614848) PREDICTED: cent (1434) 6300 465.8  1e-129
XP_016872873 (OMIM: 614845,614848) PREDICTED: cent (1434) 6300 465.8  1e-129
XP_016872860 (OMIM: 614845,614848) PREDICTED: cent (2016) 6305 466.3 1.1e-129
XP_016872869 (OMIM: 614845,614848) PREDICTED: cent (1480) 6300 465.8 1.1e-129
XP_016872868 (OMIM: 614845,614848) PREDICTED: cent (1480) 6300 465.8 1.1e-129
XP_016872866 (OMIM: 614845,614848) PREDICTED: cent (1960) 6300 465.9 1.3e-129
XP_016872864 (OMIM: 614845,614848) PREDICTED: cent (1996) 6300 465.9 1.3e-129
XP_016872863 (OMIM: 614845,614848) PREDICTED: cent (1996) 6300 465.9 1.3e-129
XP_016872862 (OMIM: 614845,614848) PREDICTED: cent (1996) 6300 465.9 1.3e-129
XP_016872855 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129
XP_011540976 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129
XP_016872854 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129
XP_016872856 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129
XP_016872853 (OMIM: 614845,614848) PREDICTED: cent (2042) 6300 466.0 1.4e-129
XP_016872857 (OMIM: 614845,614848) PREDICTED: cent (2041) 6283 464.7 3.2e-129
XP_016872865 (OMIM: 614845,614848) PREDICTED: cent (1993) 5665 420.7 5.8e-116
XP_016872875 (OMIM: 614845,614848) PREDICTED: cent (1339) 5643 419.0 1.3e-115
XP_016872867 (OMIM: 614845,614848) PREDICTED: cent (1923) 5133 382.7 1.5e-104
XP_011540992 (OMIM: 614845,614848) PREDICTED: cent ( 792)  968 85.4 1.9e-15
NP_115627 (OMIM: 611205) coiled-coil domain-contai (1476)  407 45.6  0.0034
XP_006718582 (OMIM: 611205) PREDICTED: coiled-coil (1560)  407 45.6  0.0036
XP_005245422 (OMIM: 609473) PREDICTED: cingulin is (1203)  403 45.2  0.0036
NP_065821 (OMIM: 609473) cingulin [Homo sapiens]   (1203)  403 45.2  0.0036
NP_958783 (OMIM: 131950,226670,226730,601282,61213 (4515)  403 45.7  0.0098
XP_005251041 (OMIM: 131950,226670,226730,601282,61 (4520)  403 45.7  0.0098
XP_005251040 (OMIM: 131950,226670,226730,601282,61 (4524)  403 45.7  0.0098
XP_011515433 (OMIM: 131950,226670,226730,601282,61 (4524)  403 45.7  0.0098
NP_958781 (OMIM: 131950,226670,226730,601282,61213 (4525)  403 45.7  0.0098
XP_006716652 (OMIM: 131950,226670,226730,601282,61 (4529)  403 45.7  0.0098
XP_006716653 (OMIM: 131950,226670,226730,601282,61 (4529)  403 45.7  0.0098
XP_005251039 (OMIM: 131950,226670,226730,601282,61 (4530)  403 45.7  0.0098
NP_958780 (OMIM: 131950,226670,226730,601282,61213 (4533)  403 45.7  0.0098
XP_005251038 (OMIM: 131950,226670,226730,601282,61 (4538)  403 45.7  0.0099
NP_958784 (OMIM: 131950,226670,226730,601282,61213 (4547)  403 45.7  0.0099
NP_958786 (OMIM: 131950,226670,226730,601282,61213 (4547)  403 45.7  0.0099
NP_958785 (OMIM: 131950,226670,226730,601282,61213 (4551)  403 45.7  0.0099
XP_005251037 (OMIM: 131950,226670,226730,601282,61 (4552)  403 45.7  0.0099


>>NP_001258862 (OMIM: 614845,614848) centrosomal protein  (1455 aa)
 initn: 9430 init1: 9430 opt: 9430  Z-score: 3655.8  bits: 689.0 E(85289): 6.8e-197
Smith-Waterman score: 9430; 100.0% identity (100.0% similar) in 1455 aa overlap (1-1455:1-1455)

               10        20        30        40        50        60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KSD SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KSD SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL
             1390      1400      1410      1420      1430      1440

             1450     
pF1KSD QLGLDEHNRVKVYRF
       :::::::::::::::
NP_001 QLGLDEHNRVKVYRF
             1450     

>>XP_005271514 (OMIM: 614845,614848) PREDICTED: centroso  (1455 aa)
 initn: 9430 init1: 9430 opt: 9430  Z-score: 3655.8  bits: 689.0 E(85289): 6.8e-197
Smith-Waterman score: 9430; 100.0% identity (100.0% similar) in 1455 aa overlap (1-1455:1-1455)

               10        20        30        40        50        60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHLDSTPSLTSRKIHGLS
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGSLARFSALS
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KSD SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTPLESRLGYM
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KSD SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPKPKATLSLL
             1390      1400      1410      1420      1430      1440

             1450     
pF1KSD QLGLDEHNRVKVYRF
       :::::::::::::::
XP_005 QLGLDEHNRVKVYRF
             1450     

>>XP_005271513 (OMIM: 614845,614848) PREDICTED: centroso  (1460 aa)
 initn: 6313 init1: 4930 opt: 9360  Z-score: 3628.8  bits: 684.1 E(85289): 2.2e-195
Smith-Waterman score: 9360; 99.2% identity (99.2% similar) in 1463 aa overlap (1-1455:1-1460)

               10        20        30        40        50        60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::   :::::::
XP_005 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER---LSPPLPH
              430       440       450       460       470          

              490       500       510       520       530       540
pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
       480       490       500       510       520       530       

              550       560       570       580       590       600
pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
       540       550       560       570       580       590       

              610       620       630       640       650       660
pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
       600       610       620       630       640       650       

              670       680       690       700       710       720
pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
       660       670       680       690       700       710       

              730       740       750       760       770       780
pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
       720       730       740       750       760       770       

              790       800       810       820       830       840
pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
       780       790       800       810       820       830       

              850       860       870       880       890       900
pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
       840       850       860       870       880       890       

              910       920       930       940       950       960
pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
       900       910       920       930       940       950       

              970       980       990      1000      1010      1020
pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
       960       970       980       990      1000      1010       

             1030      1040      1050      1060      1070      1080
pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
      1020      1030      1040      1050      1060      1070       

             1090      1100      1110      1120      1130      1140
pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
      1080      1090      1100      1110      1120      1130       

             1150      1160      1170      1180      1190      1200
pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
      1140      1150      1160      1170      1180      1190       

             1210      1220      1230      1240              1250  
pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPH--------LDSTPSLT
       ::::::::::::::::::::::::::::::::::::::::::::        .:::::::
XP_005 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLT
      1200      1210      1220      1230      1240      1250       

           1260      1270      1280      1290      1300      1310  
pF1KSD SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
      1260      1270      1280      1290      1300      1310       

           1320      1330      1340      1350      1360      1370  
pF1KSD LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
      1320      1330      1340      1350      1360      1370       

           1380      1390      1400      1410      1420      1430  
pF1KSD LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
      1380      1390      1400      1410      1420      1430       

           1440      1450     
pF1KSD PKATLSLLQLGLDEHNRVKVYRF
       :::::::::::::::::::::::
XP_005 PKATLSLLQLGLDEHNRVKVYRF
      1440      1450      1460

>>NP_055771 (OMIM: 614845,614848) centrosomal protein of  (1460 aa)
 initn: 6313 init1: 4930 opt: 9360  Z-score: 3628.8  bits: 684.1 E(85289): 2.2e-195
Smith-Waterman score: 9360; 99.2% identity (99.2% similar) in 1463 aa overlap (1-1455:1-1460)

               10        20        30        40        50        60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::   :::::::
NP_055 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER---LSPPLPH
              430       440       450       460       470          

              490       500       510       520       530       540
pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
       480       490       500       510       520       530       

              550       560       570       580       590       600
pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
       540       550       560       570       580       590       

              610       620       630       640       650       660
pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
       600       610       620       630       640       650       

              670       680       690       700       710       720
pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
       660       670       680       690       700       710       

              730       740       750       760       770       780
pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
       720       730       740       750       760       770       

              790       800       810       820       830       840
pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
       780       790       800       810       820       830       

              850       860       870       880       890       900
pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
       840       850       860       870       880       890       

              910       920       930       940       950       960
pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
       900       910       920       930       940       950       

              970       980       990      1000      1010      1020
pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
       960       970       980       990      1000      1010       

             1030      1040      1050      1060      1070      1080
pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
      1020      1030      1040      1050      1060      1070       

             1090      1100      1110      1120      1130      1140
pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
      1080      1090      1100      1110      1120      1130       

             1150      1160      1170      1180      1190      1200
pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
      1140      1150      1160      1170      1180      1190       

             1210      1220      1230      1240              1250  
pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPH--------LDSTPSLT
       ::::::::::::::::::::::::::::::::::::::::::::        .:::::::
NP_055 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLT
      1200      1210      1220      1230      1240      1250       

           1260      1270      1280      1290      1300      1310  
pF1KSD SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
      1260      1270      1280      1290      1300      1310       

           1320      1330      1340      1350      1360      1370  
pF1KSD LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
      1320      1330      1340      1350      1360      1370       

           1380      1390      1400      1410      1420      1430  
pF1KSD LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
      1380      1390      1400      1410      1420      1430       

           1440      1450     
pF1KSD PKATLSLLQLGLDEHNRVKVYRF
       :::::::::::::::::::::::
NP_055 PKATLSLLQLGLDEHNRVKVYRF
      1440      1450      1460

>>XP_006718851 (OMIM: 614845,614848) PREDICTED: centroso  (2025 aa)
 initn: 9399 init1: 7125 opt: 8496  Z-score: 3293.9  bits: 622.6 E(85289): 9.8e-177
Smith-Waterman score: 8496; 99.3% identity (99.4% similar) in 1332 aa overlap (132-1455:694-2025)

             110       120       130       140       150       160 
pF1KSD KLSTSGAIKKKKKKKEKKDKKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
                                     ::::::::::::::::::::::::::::::
XP_006 SSSTLRQGLVQQSSSRGLTTEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
           670       680       690       700       710       720   

             170       180       190       200       210       220 
pF1KSD RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
           730       740       750       760       770       780   

             230       240       250       260       270       280 
pF1KSD DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP
           790       800       810       820       830       840   

             290       300       310       320       330       340 
pF1KSD CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
           850       860       870       880       890       900   

             350       360       370       380       390       400 
pF1KSD ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
           910       920       930       940       950       960   

             410       420       430       440       450       460 
pF1KSD ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
           970       980       990      1000      1010      1020   

             470       480       490       500       510       520 
pF1KSD KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
          1030      1040      1050      1060      1070      1080   

             530       540       550       560       570       580 
pF1KSD SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
          1090      1100      1110      1120      1130      1140   

             590       600       610       620       630       640 
pF1KSD EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
          1150      1160      1170      1180      1190      1200   

             650       660       670       680       690       700 
pF1KSD QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
          1210      1220      1230      1240      1250      1260   

             710       720       730       740       750       760 
pF1KSD LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
          1270      1280      1290      1300      1310      1320   

             770       780       790       800       810       820 
pF1KSD RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
          1330      1340      1350      1360      1370      1380   

             830       840       850       860       870       880 
pF1KSD HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
          1390      1400      1410      1420      1430      1440   

             890       900       910       920       930       940 
pF1KSD ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
          1450      1460      1470      1480      1490      1500   

             950       960       970       980       990      1000 
pF1KSD KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
          1510      1520      1530      1540      1550      1560   

            1010      1020      1030      1040      1050      1060 
pF1KSD EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
          1570      1580      1590      1600      1610      1620   

            1070      1080      1090      1100      1110      1120 
pF1KSD PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
          1630      1640      1650      1660      1670      1680   

            1130      1140      1150      1160      1170      1180 
pF1KSD QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
          1690      1700      1710      1720      1730      1740   

            1190      1200      1210      1220      1230      1240 
pF1KSD MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
          1750      1760      1770      1780      1790      1800   

                    1250      1260      1270      1280      1290   
pF1KSD PPH--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
       :::        .::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
          1810      1820      1830      1840      1850      1860   

          1300      1310      1320      1330      1340      1350   
pF1KSD AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
          1870      1880      1890      1900      1910      1920   

          1360      1370      1380      1390      1400      1410   
pF1KSD KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
          1930      1940      1950      1960      1970      1980   

          1420      1430      1440      1450     
pF1KSD WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
       ::::::::::::::::::::::::::::::::::::::::::
XP_006 WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
          1990      2000      2010      2020     

>--
 initn: 1003 init1: 905 opt: 976  Z-score: 395.7  bits: 86.3 E(85289): 2.7e-15
Smith-Waterman score: 1001; 38.0% identity (56.4% similar) in 731 aa overlap (1-626:1-693)

               10        20        30        40        50        60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
               70        80        90       100       110       120

              130                   140       150                  
pF1KSD KKDRDPPKSSL------------ALGSSLAPVHVPLGGLAPL---------------RG-
       :::::::::::            ..  ::.:  .:  ::: :               .: 
XP_006 KKDRDPPKSSLETQPEEGLLPPSSFLCSLSPPSAP--GLADLDLDQEMQAISEGSYNKGK
              130       140       150         160       170        

                   160        170                     180       190
pF1KSD ----LVDTP---PSAL-RGSQSVSLG--SSVES---------GR---QLGELMLPSQGLK
           : :::    .:: :  : .: :  :....         ::   :  . .  .:::.
XP_006 SPGMLGDTPWRFMGALPRKLQPLSKGQPSQIHQVFADMEKILGRAPAQCRRELGDQQGLE
      180       190       200       210       220       230        

                200       210                   220        230     
pF1KSD T--SAYTKGLLGSIYEDKTALSL------LGL------GEETNEEDEEESDNQ-SVHSS-
          .:  :  ::    .   : .      ::       :   : .:  :: :: ::::. 
XP_006 KLQKATEKIYLGFSDPETEELEMRSRQQKLGTPAPQNTGLLQNMQDVVESRNQASVHSKL
      240       250       260       270       280       290        

          240                   250       260       270       280  
pF1KSD SEPLRNLHL-------DIGAL-----GGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPC
       :: ...: :       ... :     ::: . .  .  :.:::.   ::.: ..:   : 
XP_006 SEAIKGLPLKGEQHSHSLAKLSPTGPGGD-KGQSPIPMSSPEEEP--SLSSCSSGHMLPA
      300       310       320        330       340         350     

                  290       300            310          320        
pF1KSD KPS------SPGADSSLSSAVGKGRQ-GSGAR----PGLPEKEENE---KSEPKICRNLV
       . :      ::  : : ... :.: . ::: :    :::  .. ..   :. :  :.   
XP_006 RKSKLLLDSSPTEDLSWQGVPGEGGSIGSGRRRREPPGLWMEQVSKLVNKDIPGSCK---
         360       370       380       390       400       410     

      330       340       350       360       370       380        
pF1KSD TPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEL--
         ...:.  :   :: .. :.  .    : .   : :..:    .  :  .:.  : :  
XP_006 --ETEPSDPEALGASAEDLPQGLLLIPPE-TLASEPAQNPLLGRAPEEPPASEKRQALGS
              420       430        440       450       460         

         390        400       410       420       430       440    
pF1KSD -EISEHMKEPQLSD-SIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPL
        :.  . ..:.::  .. :. .:  .      : .. ::      ::::  .    . : 
XP_006 AELPYKDQKPSLSGPDLESSSSSSSN------SNLASHLG-----SPVLDEV---NNFPW
     470       480       490             500            510        

          450       460       470        480       490       500   
pF1KSD GIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPL-PHEERAQSPPRSLATEEEPPQGPEG
       ...    :. ...: ......::  : ...:: : ::  . ::: .  .  :.     : 
XP_006 NLQ----SSRGSEEGMAQSDSGL--RDQHFSPFLDPHMSHMQSPDEEQSESEDYS---ED
             520       530         540       550       560         

           510       520       530          540       550       560
pF1KSD QPEWKEAEELGEDSAASLSLQLSLQREQAP---SPPAACEKGKEQHSQAEELGPGQEEAE
       :  ...  .. . :    .: :  . .. :   :  ..:  . :.  .. :   :..:: 
XP_006 QRFYQHILQMVKISRWPEGLGLPESMQDMPCRHSASTVCCMAAESSRMSSE---GEHEAI
        570       580       590       600       610          620   

                570         580       590       600        610     
pF1KSD DPEEKVA--VSPTPPV--SPEVRSTEPVAPPEQLSEAALKAMEEAVAQ-VLEQDQRHLLE
          :. .  .:  : .   :.  .  : :  :  ..: ..    .. : ...:.. . : 
XP_006 RVMERDSRFLSWEPELLEHPQEVALAP-AWQEASQQAHFQPSSSTLRQGLVQQSSSRGLT
           630       640       650        660       670       680  

         620       630       640       650       660       670     
pF1KSD SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW
       ..  :::.: .                                                 
XP_006 TEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
            690       700       710       720       730       740  

>>XP_005271510 (OMIM: 614845,614848) PREDICTED: centroso  (2022 aa)
 initn: 7204 init1: 4930 opt: 8455  Z-score: 3278.1  bits: 619.6 E(85289): 7.5e-176
Smith-Waterman score: 8455; 99.1% identity (99.2% similar) in 1332 aa overlap (132-1455:694-2022)

             110       120       130       140       150       160 
pF1KSD KLSTSGAIKKKKKKKEKKDKKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
                                     ::::::::::::::::::::::::::::::
XP_005 SSSTLRQGLVQQSSSRGLTTEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
           670       680       690       700       710       720   

             170       180       190       200       210       220 
pF1KSD RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
           730       740       750       760       770       780   

             230       240       250       260       270       280 
pF1KSD DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP
           790       800       810       820       830       840   

             290       300       310       320       330       340 
pF1KSD CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
           850       860       870       880       890       900   

             350       360       370       380       390       400 
pF1KSD ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
           910       920       930       940       950       960   

             410       420       430       440       450       460 
pF1KSD ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
           970       980       990      1000      1010      1020   

             470       480       490       500       510       520 
pF1KSD KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
       ::::::::   :::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQSKGLEE---RLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
          1030         1040      1050      1060      1070      1080

             530       540       550       560       570       580 
pF1KSD SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
             1090      1100      1110      1120      1130      1140

             590       600       610       620       630       640 
pF1KSD EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
             1150      1160      1170      1180      1190      1200

             650       660       670       680       690       700 
pF1KSD QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
             1210      1220      1230      1240      1250      1260

             710       720       730       740       750       760 
pF1KSD LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
             1270      1280      1290      1300      1310      1320

             770       780       790       800       810       820 
pF1KSD RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
             1330      1340      1350      1360      1370      1380

             830       840       850       860       870       880 
pF1KSD HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
             1390      1400      1410      1420      1430      1440

             890       900       910       920       930       940 
pF1KSD ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
             1450      1460      1470      1480      1490      1500

             950       960       970       980       990      1000 
pF1KSD KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
             1510      1520      1530      1540      1550      1560

            1010      1020      1030      1040      1050      1060 
pF1KSD EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
             1570      1580      1590      1600      1610      1620

            1070      1080      1090      1100      1110      1120 
pF1KSD PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
             1630      1640      1650      1660      1670      1680

            1130      1140      1150      1160      1170      1180 
pF1KSD QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
             1690      1700      1710      1720      1730      1740

            1190      1200      1210      1220      1230      1240 
pF1KSD MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
             1750      1760      1770      1780      1790      1800

                    1250      1260      1270      1280      1290   
pF1KSD PPH--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
       :::        .::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
             1810      1820      1830      1840      1850      1860

          1300      1310      1320      1330      1340      1350   
pF1KSD AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
             1870      1880      1890      1900      1910      1920

          1360      1370      1380      1390      1400      1410   
pF1KSD KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
             1930      1940      1950      1960      1970      1980

          1420      1430      1440      1450     
pF1KSD WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
       ::::::::::::::::::::::::::::::::::::::::::
XP_005 WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
             1990      2000      2010      2020  

>--
 initn: 1003 init1: 905 opt: 976  Z-score: 395.7  bits: 86.3 E(85289): 2.7e-15
Smith-Waterman score: 1001; 38.0% identity (56.4% similar) in 731 aa overlap (1-626:1-693)

               10        20        30        40        50        60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
               70        80        90       100       110       120

              130                   140       150                  
pF1KSD KKDRDPPKSSL------------ALGSSLAPVHVPLGGLAPL---------------RG-
       :::::::::::            ..  ::.:  .:  ::: :               .: 
XP_005 KKDRDPPKSSLETQPEEGLLPPSSFLCSLSPPSAP--GLADLDLDQEMQAISEGSYNKGK
              130       140       150         160       170        

                   160        170                     180       190
pF1KSD ----LVDTP---PSAL-RGSQSVSLG--SSVES---------GR---QLGELMLPSQGLK
           : :::    .:: :  : .: :  :....         ::   :  . .  .:::.
XP_005 SPGMLGDTPWRFMGALPRKLQPLSKGQPSQIHQVFADMEKILGRAPAQCRRELGDQQGLE
      180       190       200       210       220       230        

                200       210                   220        230     
pF1KSD T--SAYTKGLLGSIYEDKTALSL------LGL------GEETNEEDEEESDNQ-SVHSS-
          .:  :  ::    .   : .      ::       :   : .:  :: :: ::::. 
XP_005 KLQKATEKIYLGFSDPETEELEMRSRQQKLGTPAPQNTGLLQNMQDVVESRNQASVHSKL
      240       250       260       270       280       290        

          240                   250       260       270       280  
pF1KSD SEPLRNLHL-------DIGAL-----GGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPC
       :: ...: :       ... :     ::: . .  .  :.:::.   ::.: ..:   : 
XP_005 SEAIKGLPLKGEQHSHSLAKLSPTGPGGD-KGQSPIPMSSPEEEP--SLSSCSSGHMLPA
      300       310       320        330       340         350     

                  290       300            310          320        
pF1KSD KPS------SPGADSSLSSAVGKGRQ-GSGAR----PGLPEKEENE---KSEPKICRNLV
       . :      ::  : : ... :.: . ::: :    :::  .. ..   :. :  :.   
XP_005 RKSKLLLDSSPTEDLSWQGVPGEGGSIGSGRRRREPPGLWMEQVSKLVNKDIPGSCK---
         360       370       380       390       400       410     

      330       340       350       360       370       380        
pF1KSD TPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEL--
         ...:.  :   :: .. :.  .    : .   : :..:    .  :  .:.  : :  
XP_005 --ETEPSDPEALGASAEDLPQGLLLIPPE-TLASEPAQNPLLGRAPEEPPASEKRQALGS
              420       430        440       450       460         

         390        400       410       420       430       440    
pF1KSD -EISEHMKEPQLSD-SIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPL
        :.  . ..:.::  .. :. .:  .      : .. ::      ::::  .    . : 
XP_005 AELPYKDQKPSLSGPDLESSSSSSSN------SNLASHLG-----SPVLDEV---NNFPW
     470       480       490             500            510        

          450       460       470        480       490       500   
pF1KSD GIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPL-PHEERAQSPPRSLATEEEPPQGPEG
       ...    :. ...: ......::  : ...:: : ::  . ::: .  .  :.     : 
XP_005 NLQ----SSRGSEEGMAQSDSGL--RDQHFSPFLDPHMSHMQSPDEEQSESEDYS---ED
             520       530         540       550       560         

           510       520       530          540       550       560
pF1KSD QPEWKEAEELGEDSAASLSLQLSLQREQAP---SPPAACEKGKEQHSQAEELGPGQEEAE
       :  ...  .. . :    .: :  . .. :   :  ..:  . :.  .. :   :..:: 
XP_005 QRFYQHILQMVKISRWPEGLGLPESMQDMPCRHSASTVCCMAAESSRMSSE---GEHEAI
        570       580       590       600       610          620   

                570         580       590       600        610     
pF1KSD DPEEKVA--VSPTPPV--SPEVRSTEPVAPPEQLSEAALKAMEEAVAQ-VLEQDQRHLLE
          :. .  .:  : .   :.  .  : :  :  ..: ..    .. : ...:.. . : 
XP_005 RVMERDSRFLSWEPELLEHPQEVALAP-AWQEASQQAHFQPSSSTLRQGLVQQSSSRGLT
           630       640       650        660       670       680  

         620       630       640       650       660       670     
pF1KSD SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW
       ..  :::.: .                                                 
XP_005 TEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
            690       700       710       720       730       740  

>>XP_006718857 (OMIM: 614845,614848) PREDICTED: centroso  (1434 aa)
 initn: 7831 init1: 4930 opt: 7669  Z-score: 2977.2  bits: 563.5 E(85289): 4.3e-159
Smith-Waterman score: 9125; 97.4% identity (97.5% similar) in 1463 aa overlap (1-1455:1-1434)

               10        20        30        40        50        60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_006 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQ-----------
              190       200       210       220                    

              250       260       270       280       290       300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
                      :::::::::::::::::::::::::::::::::::::::::::::
XP_006 ---------------ESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
                    230       240       250       260       270    

              310       320       330       340       350       360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
          280       290       300       310       320       330    

              370       380       390       400       410       420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
          340       350       360       370       380       390    

              430       440       450       460       470       480
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPLPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::   :::::::
XP_006 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER---LSPPLPH
          400       410       420       430       440          450 

              490       500       510       520       530       540
pF1KSD EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACE
             460       470       480       490       500       510 

              550       560       570       580       590       600
pF1KSD KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEE
             520       530       540       550       560       570 

              610       620       630       640       650       660
pF1KSD AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEE
             580       590       600       610       620       630 

              670       680       690       700       710       720
pF1KSD EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQK
             640       650       660       670       680       690 

              730       740       750       760       770       780
pF1KSD NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVATLEKEHSAELERL
             700       710       720       730       740       750 

              790       800       810       820       830       840
pF1KSD CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLR
             760       770       780       790       800       810 

              850       860       870       880       890       900
pF1KSD EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHER
             820       830       840       850       860       870 

              910       920       930       940       950       960
pF1KSD ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQ
             880       890       900       910       920       930 

              970       980       990      1000      1010      1020
pF1KSD QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVDL
             940       950       960       970       980       990 

             1030      1040      1050      1060      1070      1080
pF1KSD LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKE
            1000      1010      1020      1030      1040      1050 

             1090      1100      1110      1120      1130      1140
pF1KSD VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQH
            1060      1070      1080      1090      1100      1110 

             1150      1160      1170      1180      1190      1200
pF1KSD WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKKKEEKLNQLE
            1120      1130      1140      1150      1160      1170 

             1210      1220      1230      1240              1250  
pF1KSD SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPH--------LDSTPSLT
       ::::::::::::::::::::::::::::::::::::::::::::        .:::::::
XP_006 SSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPPHREWWRQQRIDSTPSLT
            1180      1190      1200      1210      1220      1230 

           1260      1270      1280      1290      1300      1310  
pF1KSD SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQLPPRDPKSTPTPTYYGS
            1240      1250      1260      1270      1280      1290 

           1320      1330      1340      1350      1360      1370  
pF1KSD LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKWRKYFPSGIPLLSNSPTP
            1300      1310      1320      1330      1340      1350 

           1380      1390      1400      1410      1420      1430  
pF1KSD LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWLERVKNDPRLPLFSSTPK
            1360      1370      1380      1390      1400      1410 

           1440      1450     
pF1KSD PKATLSLLQLGLDEHNRVKVYRF
       :::::::::::::::::::::::
XP_006 PKATLSLLQLGLDEHNRVKVYRF
            1420      1430    

>>XP_016872861 (OMIM: 614845,614848) PREDICTED: centroso  (1996 aa)
 initn: 7817 init1: 4930 opt: 7669  Z-score: 2975.3  bits: 563.6 E(85289): 5.5e-159
Smith-Waterman score: 8220; 97.1% identity (97.2% similar) in 1332 aa overlap (132-1455:694-1996)

             110       120       130       140       150       160 
pF1KSD KLSTSGAIKKKKKKKEKKDKKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
                                     ::::::::::::::::::::::::::::::
XP_016 SSSTLRQGLVQQSSSRGLTTEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSAL
           670       680       690       700       710       720   

             170       180       190       200       210       220 
pF1KSD RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGSQSVSLGSSVESGRQLGELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEE
           730       740       750       760       770       780   

             230       240       250       260       270       280 
pF1KSD DEEESDNQSVHSSSEPLRNLHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTP
       ::::::::                          ::::::::::::::::::::::::::
XP_016 DEEESDNQ--------------------------ESLRTSQPEEKKDVSLDSDAAGPPTP
           790                                 800       810       

             290       300       310       320       330       340 
pF1KSD CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAK
       820       830       840       850       860       870       

             350       360       370       380       390       400 
pF1KSD ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSI
       880       890       900       910       920       930       

             410       420       430       440       450       460 
pF1KSD ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQS
       940       950       960       970       980       990       

             470       480       490       500       510       520 
pF1KSD KQSKGLEERYHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
       ::::::::   :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQSKGLEE---RLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASL
      1000         1010      1020      1030      1040      1050    

             530       540       550       560       570       580 
pF1KSD SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRST
         1060      1070      1080      1090      1100      1110    

             590       600       610       620       630       640 
pF1KSD EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQ
         1120      1130      1140      1150      1160      1170    

             650       660       670       680       690       700 
pF1KSD QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQK
         1180      1190      1200      1210      1220      1230    

             710       720       730       740       750       760 
pF1KSD LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGE
         1240      1250      1260      1270      1280      1290    

             770       780       790       800       810       820 
pF1KSD RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRV
         1300      1310      1320      1330      1340      1350    

             830       840       850       860       870       880 
pF1KSD HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRA
         1360      1370      1380      1390      1400      1410    

             890       900       910       920       930       940 
pF1KSD ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDV
         1420      1430      1440      1450      1460      1470    

             950       960       970       980       990      1000 
pF1KSD KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLR
         1480      1490      1500      1510      1520      1530    

            1010      1020      1030      1040      1050      1060 
pF1KSD EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFE
         1540      1550      1560      1570      1580      1590    

            1070      1080      1090      1100      1110      1120 
pF1KSD PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLV
         1600      1610      1620      1630      1640      1650    

            1130      1140      1150      1160      1170      1180 
pF1KSD QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQTRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSA
         1660      1670      1680      1690      1700      1710    

            1190      1200      1210      1220      1230      1240 
pF1KSD MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRKGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFS
         1720      1730      1740      1750      1760      1770    

                    1250      1260      1270      1280      1290   
pF1KSD PPH--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
       :::        .::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPHREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMP
         1780      1790      1800      1810      1820      1830    

          1300      1310      1320      1330      1340      1350   
pF1KSD AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQLPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLE
         1840      1850      1860      1870      1880      1890    

          1360      1370      1380      1390      1400      1410   
pF1KSD KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KWRKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRR
         1900      1910      1920      1930      1940      1950    

          1420      1430      1440      1450     
pF1KSD WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
       ::::::::::::::::::::::::::::::::::::::::::
XP_016 WLERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
         1960      1970      1980      1990      

>--
 initn: 1003 init1: 905 opt: 976  Z-score: 395.8  bits: 86.3 E(85289): 2.6e-15
Smith-Waterman score: 1001; 38.0% identity (56.4% similar) in 731 aa overlap (1-626:1-693)

               10        20        30        40        50        60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
               70        80        90       100       110       120

              130                   140       150                  
pF1KSD KKDRDPPKSSL------------ALGSSLAPVHVPLGGLAPL---------------RG-
       :::::::::::            ..  ::.:  .:  ::: :               .: 
XP_016 KKDRDPPKSSLETQPEEGLLPPSSFLCSLSPPSAP--GLADLDLDQEMQAISEGSYNKGK
              130       140       150         160       170        

                   160        170                     180       190
pF1KSD ----LVDTP---PSAL-RGSQSVSLG--SSVES---------GR---QLGELMLPSQGLK
           : :::    .:: :  : .: :  :....         ::   :  . .  .:::.
XP_016 SPGMLGDTPWRFMGALPRKLQPLSKGQPSQIHQVFADMEKILGRAPAQCRRELGDQQGLE
      180       190       200       210       220       230        

                200       210                   220        230     
pF1KSD T--SAYTKGLLGSIYEDKTALSL------LGL------GEETNEEDEEESDNQ-SVHSS-
          .:  :  ::    .   : .      ::       :   : .:  :: :: ::::. 
XP_016 KLQKATEKIYLGFSDPETEELEMRSRQQKLGTPAPQNTGLLQNMQDVVESRNQASVHSKL
      240       250       260       270       280       290        

          240                   250       260       270       280  
pF1KSD SEPLRNLHL-------DIGAL-----GGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPC
       :: ...: :       ... :     ::: . .  .  :.:::.   ::.: ..:   : 
XP_016 SEAIKGLPLKGEQHSHSLAKLSPTGPGGD-KGQSPIPMSSPEEEP--SLSSCSSGHMLPA
      300       310       320        330       340         350     

                  290       300            310          320        
pF1KSD KPS------SPGADSSLSSAVGKGRQ-GSGAR----PGLPEKEENE---KSEPKICRNLV
       . :      ::  : : ... :.: . ::: :    :::  .. ..   :. :  :.   
XP_016 RKSKLLLDSSPTEDLSWQGVPGEGGSIGSGRRRREPPGLWMEQVSKLVNKDIPGSCK---
         360       370       380       390       400       410     

      330       340       350       360       370       380        
pF1KSD TPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQEL--
         ...:.  :   :: .. :.  .    : .   : :..:    .  :  .:.  : :  
XP_016 --ETEPSDPEALGASAEDLPQGLLLIPPE-TLASEPAQNPLLGRAPEEPPASEKRQALGS
              420       430        440       450       460         

         390        400       410       420       430       440    
pF1KSD -EISEHMKEPQLSD-SIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGGACRQAQQPL
        :.  . ..:.::  .. :. .:  .      : .. ::      ::::  .    . : 
XP_016 AELPYKDQKPSLSGPDLESSSSSSSN------SNLASHLG-----SPVLDEV---NNFPW
     470       480       490             500            510        

          450       460       470        480       490       500   
pF1KSD GIEDKDDSQSSQDELQSKQSKGLEERYHRLSPPL-PHEERAQSPPRSLATEEEPPQGPEG
       ...    :. ...: ......::  : ...:: : ::  . ::: .  .  :.     : 
XP_016 NLQ----SSRGSEEGMAQSDSGL--RDQHFSPFLDPHMSHMQSPDEEQSESEDYS---ED
             520       530         540       550       560         

           510       520       530          540       550       560
pF1KSD QPEWKEAEELGEDSAASLSLQLSLQREQAP---SPPAACEKGKEQHSQAEELGPGQEEAE
       :  ...  .. . :    .: :  . .. :   :  ..:  . :.  .. :   :..:: 
XP_016 QRFYQHILQMVKISRWPEGLGLPESMQDMPCRHSASTVCCMAAESSRMSSE---GEHEAI
        570       580       590       600       610          620   

                570         580       590       600        610     
pF1KSD DPEEKVA--VSPTPPV--SPEVRSTEPVAPPEQLSEAALKAMEEAVAQ-VLEQDQRHLLE
          :. .  .:  : .   :.  .  : :  :  ..: ..    .. : ...:.. . : 
XP_016 RVMERDSRFLSWEPELLEHPQEVALAP-AWQEASQQAHFQPSSSTLRQGLVQQSSSRGLT
           630       640       650        660       670       680  

         620       630       640       650       660       670     
pF1KSD SKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSW
       ..  :::.: .                                                 
XP_016 TEPGKMQHLNQALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
            690       700       710       720       730       740  

>>XP_016872871 (OMIM: 614845,614848) PREDICTED: centroso  (1454 aa)
 initn: 7810 init1: 4909 opt: 6334  Z-score: 2462.6  bits: 468.3 E(85289): 2e-130
Smith-Waterman score: 9093; 96.3% identity (96.4% similar) in 1480 aa overlap (1-1455:1-1454)

               10        20        30        40        50        60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_016 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQ-----------
              190       200       210       220                    

              250       260       270       280       290       300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
                      :::::::::::::::::::::::::::::::::::::::::::::
XP_016 ---------------ESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
                    230       240       250       260       270    

              310       320       330       340       350       360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
          280       290       300       310       320       330    

              370       380       390       400       410       420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
          340       350       360       370       380       390    

              430       440       450       460       470          
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER----------
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_016 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEESSLPALQMEGP
          400       410       420       430       440       450    

                     480       490       500       510       520   
pF1KSD -------YHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL
                :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSAALPGLTRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL
          460       470       480       490       500       510    

           530       540       550       560       570       580   
pF1KSD QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP
          520       530       540       550       560       570    

           590       600       610       620       630       640   
pF1KSD VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK
          580       590       600       610       620       630    

           650       660       670       680       690       700   
pF1KSD EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR
          640       650       660       670       680       690    

           710       720       730       740       750       760   
pF1KSD EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK
          700       710       720       730       740       750    

           770       780       790       800       810       820   
pF1KSD EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ
          760       770       780       790       800       810    

           830       840       850       860       870       880   
pF1KSD KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL
          820       830       840       850       860       870    

           890       900       910       920       930       940   
pF1KSD LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA
          880       890       900       910       920       930    

           950       960       970       980       990      1000   
pF1KSD RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI
          940       950       960       970       980       990    

          1010      1020      1030      1040      1050      1060   
pF1KSD LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD
         1000      1010      1020      1030      1040      1050    

          1070      1080      1090      1100      1110      1120   
pF1KSD LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ
         1060      1070      1080      1090      1100      1110    

          1130      1140      1150      1160      1170      1180   
pF1KSD TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR
         1120      1130      1140      1150      1160      1170    

          1190      1200      1210      1220      1230      1240   
pF1KSD KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP
         1180      1190      1200      1210      1220      1230    

                  1250      1260      1270      1280      1290     
pF1KSD H--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ
       :        .::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ
         1240      1250      1260      1270      1280      1290    

        1300      1310      1320      1330      1340      1350     
pF1KSD LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW
         1300      1310      1320      1330      1340      1350    

        1360      1370      1380      1390      1400      1410     
pF1KSD RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL
         1360      1370      1380      1390      1400      1410    

        1420      1430      1440      1450     
pF1KSD ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
       ::::::::::::::::::::::::::::::::::::::::
XP_016 ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
         1420      1430      1440      1450    

>>XP_016872870 (OMIM: 614845,614848) PREDICTED: centroso  (1454 aa)
 initn: 7810 init1: 4909 opt: 6334  Z-score: 2462.6  bits: 468.3 E(85289): 2e-130
Smith-Waterman score: 9093; 96.3% identity (96.4% similar) in 1480 aa overlap (1-1455:1-1454)

               10        20        30        40        50        60
pF1KSD MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGRPLRIGDQLVLEEDYDETYIPSEQEILEFAREIGIDPIKEPELMWLAREGIVAPLPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWKPCQDITGDIYYFNFANGQSMWDHPCDEHYRSLVIQERAKLSTSGAIKKKKKKKEKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDRDPPKSSLALGSSLAPVHVPLGGLAPLRGLVDTPPSALRGSQSVSLGSSVESGRQLG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQSVHSSSEPLRN
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_016 ELMLPSQGLKTSAYTKGLLGSIYEDKTALSLLGLGEETNEEDEEESDNQ-----------
              190       200       210       220                    

              250       260       270       280       290       300
pF1KSD LHLDIGALGGDFEYEESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
                      :::::::::::::::::::::::::::::::::::::::::::::
XP_016 ---------------ESLRTSQPEEKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKG
                    230       240       250       260       270    

              310       320       330       340       350       360
pF1KSD RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQGSGARPGLPEKEENEKSEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSR
          280       290       300       310       320       330    

              370       380       390       400       410       420
pF1KSD REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REEAAKEPKKKASALEEGSSDASQELEISEHMKEPQLSDSIASDPKSFHGLDFGFRSRIS
          340       350       360       370       380       390    

              430       440       450       460       470          
pF1KSD EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEER----------
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_016 EHLLDVDVLSPVLGGACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEESSLPALQMEGP
          400       410       420       430       440       450    

                     480       490       500       510       520   
pF1KSD -------YHRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL
                :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSAALPGLTRLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKEAEELGEDSAASLSL
          460       470       480       490       500       510    

           530       540       550       560       570       580   
pF1KSD QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEP
          520       530       540       550       560       570    

           590       600       610       620       630       640   
pF1KSD VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAPPEQLSEAALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQK
          580       590       600       610       620       630    

           650       660       670       680       690       700   
pF1KSD EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR
          640       650       660       670       680       690    

           710       720       730       740       750       760   
pF1KSD EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK
          700       710       720       730       740       750    

           770       780       790       800       810       820   
pF1KSD EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ
          760       770       780       790       800       810    

           830       840       850       860       870       880   
pF1KSD KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL
          820       830       840       850       860       870    

           890       900       910       920       930       940   
pF1KSD LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETRAKDVKA
          880       890       900       910       920       930    

           950       960       970       980       990      1000   
pF1KSD RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSNQQLREI
          940       950       960       970       980       990    

          1010      1020      1030      1040      1050      1060   
pF1KSD LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPD
         1000      1010      1020      1030      1040      1050    

          1070      1080      1090      1100      1110      1120   
pF1KSD LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQ
         1060      1070      1080      1090      1100      1110    

          1130      1140      1150      1160      1170      1180   
pF1KSD TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSMRRRQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMR
         1120      1130      1140      1150      1160      1170    

          1190      1200      1210      1220      1230      1240   
pF1KSD KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGHNLLKKKEEKLNQLESSLWEEASDEGTLGGSPTKKAVTFDLSDMDSLSSESSESFSPP
         1180      1190      1200      1210      1220      1230    

                  1250      1260      1270      1280      1290     
pF1KSD H--------LDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ
       :        .::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HREWWRQQRIDSTPSLTSRKIHGLSHSLRQISSQLSSVLSILDSLNPQSPPPLLASMPAQ
         1240      1250      1260      1270      1280      1290    

        1300      1310      1320      1330      1340      1350     
pF1KSD LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPPRDPKSTPTPTYYGSLARFSALSSATPTSTQWAWDSGQGPRLPSSVAQTVDDFLLEKW
         1300      1310      1320      1330      1340      1350    

        1360      1370      1380      1390      1400      1410     
pF1KSD RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKYFPSGIPLLSNSPTPLESRLGYMSASEQLRLLQHSHSQVPEAGSTTFQGIIEANRRWL
         1360      1370      1380      1390      1400      1410    

        1420      1430      1440      1450     
pF1KSD ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
       ::::::::::::::::::::::::::::::::::::::::
XP_016 ERVKNDPRLPLFSSTPKPKATLSLLQLGLDEHNRVKVYRF
         1420      1430      1440      1450    




1455 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 04:46:18 2016 done: Thu Nov  3 04:46:20 2016
 Total Scan time: 19.480 Total Display time:  0.830

Function used was FASTA [36.3.4 Apr, 2011]
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