Result of FASTA (omim) for
pF1KSDA1075
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1075, 1409 aa
1>>>pF1KSDA1075 1409 - 1409 aa - 1409 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.2637+/-0.000466; mu= -10.9356+/- 0.029
mean_var=601.6501+/-130.310, 0's: 0 Z-trim(124.1): 207 B-trim: 3700 in 2/59
Lambda= 0.052288
statistics sampled from 45003 (45260) to 45003 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.531), width: 16
Scan time: 20.550
The best scores are: opt bits E(85289)
NP_736610 (OMIM: 607717) tensin-2 isoform 2 [Homo (1409) 9880 761.5 9.6e-219
NP_056134 (OMIM: 607717) tensin-2 isoform 1 [Homo (1419) 9743 751.2 1.2e-215
XP_011536381 (OMIM: 607717) PREDICTED: tensin-2 is (1403) 9725 749.8 3.2e-215
NP_938072 (OMIM: 607717) tensin-2 isoform 3 [Homo (1285) 9048 698.7 7e-200
XP_016874578 (OMIM: 607717) PREDICTED: tensin-2 is (1412) 6694 521.2 2.1e-146
XP_006719366 (OMIM: 607717) PREDICTED: tensin-2 is (1418) 6694 521.2 2.2e-146
XP_016874577 (OMIM: 607717) PREDICTED: tensin-2 is (1418) 6694 521.2 2.2e-146
XP_006719365 (OMIM: 607717) PREDICTED: tensin-2 is (1428) 6694 521.2 2.2e-146
XP_016868027 (OMIM: 606825) PREDICTED: tensin-3 is (1559) 1639 139.9 1.4e-31
XP_011513780 (OMIM: 606825) PREDICTED: tensin-3 is (1534) 1637 139.8 1.6e-31
XP_011513779 (OMIM: 606825) PREDICTED: tensin-3 is (1548) 1637 139.8 1.6e-31
XP_011513778 (OMIM: 606825) PREDICTED: tensin-3 is (1561) 1637 139.8 1.6e-31
XP_011513781 (OMIM: 606825) PREDICTED: tensin-3 is (1488) 1615 138.1 4.8e-31
XP_016868026 (OMIM: 606825) PREDICTED: tensin-3 is (1548) 1612 137.9 5.8e-31
NP_072174 (OMIM: 600076) tensin-1 isoform 1 [Homo (1735) 1595 136.6 1.5e-30
XP_016868028 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 1589 136.1 1.8e-30
XP_011513783 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 1589 136.1 1.8e-30
XP_011513784 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 1589 136.1 1.8e-30
NP_073585 (OMIM: 606825) tensin-3 [Homo sapiens] (1445) 1589 136.1 1.8e-30
XP_011513785 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 1589 136.1 1.8e-30
XP_011513782 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 1589 136.1 1.8e-30
XP_016860297 (OMIM: 600076) PREDICTED: tensin-1 is (1727) 1591 136.3 1.9e-30
XP_011510025 (OMIM: 600076) PREDICTED: tensin-1 is (1714) 1590 136.3 2e-30
NP_001294952 (OMIM: 600076) tensin-1 isoform 3 [Ho (1714) 1590 136.3 2e-30
NP_001294951 (OMIM: 600076) tensin-1 isoform 2 [Ho (1721) 1589 136.2 2.1e-30
XP_016860300 (OMIM: 600076) PREDICTED: tensin-1 is (1808) 1569 134.7 6.1e-30
XP_016860301 (OMIM: 600076) PREDICTED: tensin-1 is (1808) 1569 134.7 6.1e-30
XP_016860291 (OMIM: 600076) PREDICTED: tensin-1 is (1880) 1559 134.0 1.1e-29
XP_016860294 (OMIM: 600076) PREDICTED: tensin-1 is (1824) 1489 128.7 4e-28
XP_016860305 (OMIM: 600076) PREDICTED: tensin-1 is ( 926) 1462 126.3 1e-27
XP_011510030 (OMIM: 600076) PREDICTED: tensin-1 is ( 846) 1460 126.1 1.1e-27
XP_016860306 (OMIM: 600076) PREDICTED: tensin-1 is ( 911) 1451 125.5 1.8e-27
XP_016860304 (OMIM: 600076) PREDICTED: tensin-1 is (1352) 1456 126.1 1.8e-27
XP_016860303 (OMIM: 600076) PREDICTED: tensin-1 is (1352) 1456 126.1 1.8e-27
XP_016860302 (OMIM: 600076) PREDICTED: tensin-1 is (1518) 1456 126.1 2e-27
XP_016860296 (OMIM: 600076) PREDICTED: tensin-1 is (1802) 1440 125.0 5.2e-27
XP_016860295 (OMIM: 600076) PREDICTED: tensin-1 is (1815) 1440 125.0 5.2e-27
XP_011510017 (OMIM: 600076) PREDICTED: tensin-1 is (1831) 1440 125.0 5.2e-27
XP_011510015 (OMIM: 600076) PREDICTED: tensin-1 is (1839) 1440 125.0 5.3e-27
XP_011510014 (OMIM: 600076) PREDICTED: tensin-1 is (1844) 1440 125.0 5.3e-27
XP_016860293 (OMIM: 600076) PREDICTED: tensin-1 is (1852) 1440 125.0 5.3e-27
XP_016860292 (OMIM: 600076) PREDICTED: tensin-1 is (1867) 1440 125.0 5.3e-27
XP_016860290 (OMIM: 600076) PREDICTED: tensin-1 is (1895) 1440 125.0 5.4e-27
XP_016860299 (OMIM: 600076) PREDICTED: tensin-1 is (1896) 1440 125.0 5.4e-27
XP_016860298 (OMIM: 600076) PREDICTED: tensin-1 is (1896) 1440 125.0 5.4e-27
XP_011513786 (OMIM: 606825) PREDICTED: tensin-3 is (1002) 1329 116.3 1.1e-24
NP_116254 (OMIM: 608385) tensin-4 precursor [Homo ( 715) 1072 96.8 6.2e-19
XP_005257801 (OMIM: 608385) PREDICTED: tensin-4 is ( 714) 1069 96.6 7.3e-19
XP_016880726 (OMIM: 608385) PREDICTED: tensin-4 is ( 672) 629 63.4 6.8e-09
XP_016880725 (OMIM: 608385) PREDICTED: tensin-4 is ( 689) 536 56.4 9e-07
>>NP_736610 (OMIM: 607717) tensin-2 isoform 2 [Homo sapi (1409 aa)
initn: 9880 init1: 9880 opt: 9880 Z-score: 4048.1 bits: 761.5 E(85289): 9.6e-219
Smith-Waterman score: 9880; 99.9% identity (99.9% similar) in 1409 aa overlap (1-1409:1-1409)
10 20 30 40 50 60
pF1KSD MKSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 MKSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 RVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 LDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 KRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD IVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 IVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 PLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 KGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD VFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 VFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD LDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 LDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYRE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 PCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 PATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD AGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 AGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 PGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPEL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD PSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 PSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 RGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD GPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 GPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFW
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD YKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 YKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD HFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRILSKDPLEETPEAPVP
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_736 HFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD TNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 TNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD QGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_736 QGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENV
1330 1340 1350 1360 1370 1380
1390 1400
pF1KSD CHLFAELDPDQPAGAIVTFITKVLLGQRK
:::::::::::::::::::::::::::::
NP_736 CHLFAELDPDQPAGAIVTFITKVLLGQRK
1390 1400
>>NP_056134 (OMIM: 607717) tensin-2 isoform 1 [Homo sapi (1419 aa)
initn: 9739 init1: 9739 opt: 9743 Z-score: 3992.3 bits: 751.2 E(85289): 1.2e-215
Smith-Waterman score: 9743; 99.1% identity (99.4% similar) in 1402 aa overlap (12-1409:18-1419)
10 20 30 40 50
pF1KSD MKSSGPVERLLRALG---RRDSS-RAASRPRKAEPHSFREKVFRKKPPVCAVCK
.::: :..: : : .:::::::::::::::::::::::::
NP_056 MDGGGVCVGRGDLLSSPQALGQLLRKESRPRRAMKPRKAEPHSFREKVFRKKPPVCAVCK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD VTIDGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VTIDGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD QRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD DKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD CKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD LSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD CISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD RFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD LTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD PPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSR
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD HCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEG
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD LYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD REAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 REAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSY
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD TMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGS
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD ISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTL
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD PRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVS
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KSD QAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLP
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KSD GLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQ
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KSD PPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNV
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KSD KFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPW
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KSD KGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRILSKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_056 KGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDP
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KSD LEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPT
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KSD PAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVA
1330 1340 1350 1360 1370 1380
1380 1390 1400
pF1KSD KKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
:::::::::::::::::::::::::::::::::::::::
NP_056 KKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
1390 1400 1410
>>XP_011536381 (OMIM: 607717) PREDICTED: tensin-2 isofor (1403 aa)
initn: 9725 init1: 9725 opt: 9725 Z-score: 3985.0 bits: 749.8 E(85289): 3.2e-215
Smith-Waterman score: 9725; 99.9% identity (99.9% similar) in 1384 aa overlap (26-1409:20-1403)
10 20 30 40 50 60
pF1KSD MKSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSC
:::::::::::::::::::::::::::::::::::
XP_011 MSLARPGWPSAHPLSPRLFPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSC
10 20 30 40 50
70 80 90 100 110 120
pF1KSD RVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD LDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD KRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD IVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD PLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD KGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEF
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD VFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDG
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQE
480 490 500 510 520 530
550 560 570 580 590 600
pF1KSD LDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYRE
540 550 560 570 580 590
610 620 630 640 650 660
pF1KSD PCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGK
600 610 620 630 640 650
670 680 690 700 710 720
pF1KSD PATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KSD AGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGH
720 730 740 750 760 770
790 800 810 820 830 840
pF1KSD PGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQ
780 790 800 810 820 830
850 860 870 880 890 900
pF1KSD SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCS
840 850 860 870 880 890
910 920 930 940 950 960
pF1KSD ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPEL
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KSD PSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGP
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KSD RGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLP
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KSD GPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFW
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KSD YKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVR
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KSD HFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRILSKDPLEETPEAPVP
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_011 HFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVP
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KSD TNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSA
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KSD QGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENV
1320 1330 1340 1350 1360 1370
1390 1400
pF1KSD CHLFAELDPDQPAGAIVTFITKVLLGQRK
:::::::::::::::::::::::::::::
XP_011 CHLFAELDPDQPAGAIVTFITKVLLGQRK
1380 1390 1400
>>NP_938072 (OMIM: 607717) tensin-2 isoform 3 [Homo sapi (1285 aa)
initn: 9048 init1: 9048 opt: 9048 Z-score: 3709.5 bits: 698.7 E(85289): 7e-200
Smith-Waterman score: 9048; 99.9% identity (99.9% similar) in 1285 aa overlap (125-1409:1-1285)
100 110 120 130 140 150
pF1KSD RRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRH
::::::::::::::::::::::::::::::
NP_938 MERRWDLDLTYVTERILAAAFPARPDEQRH
10 20 30
160 170 180 190 200 210
pF1KSD RGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 RGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKA
40 50 60 70 80 90
220 230 240 250 260 270
pF1KSD METWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 METWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVAT
100 110 120 130 140 150
280 290 300 310 320 330
pF1KSD ELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLV
160 170 180 190 200 210
340 350 360 370 380 390
pF1KSD YTSGVYHIAGPGPQQLCISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 YTSGVYHIAGPGPQQLCISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGP
220 230 240 250 260 270
400 410 420 430 440 450
pF1KSD QLTFPKDQLDEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 QLTFPKDQLDEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWD
280 290 300 310 320 330
460 470 480 490 500 510
pF1KSD SYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSG
340 350 360 370 380 390
520 530 540 550 560 570
pF1KSD HSSTLTTEPAAESPGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HSSTLTTEPAAESPGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGG
400 410 420 430 440 450
580 590 600 610 620 630
pF1KSD GPHLGVYPGHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GPHLGVYPGHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYA
460 470 480 490 500 510
640 650 660 670 680 690
pF1KSD EASMEKRRLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 EASMEKRRLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACE
520 530 540 550 560 570
700 710 720 730 740 750
pF1KSD EKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 EKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSC
580 590 600 610 620 630
760 770 780 790 800 810
pF1KSD LKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGE
640 650 660 670 680 690
820 830 840 850 860 870
pF1KSD GRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAES
700 710 720 730 740 750
880 890 900 910 920 930
pF1KSD LEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTS
760 770 780 790 800 810
940 950 960 970 980 990
pF1KSD APTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 APTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGG
820 830 840 850 860 870
1000 1010 1020 1030 1040 1050
pF1KSD HSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPT
880 890 900 910 920 930
1060 1070 1080 1090 1100 1110
pF1KSD PAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDN
940 950 960 970 980 990
1120 1130 1140 1150 1160 1170
pF1KSD VPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAY
1000 1010 1020 1030 1040 1050
1180 1190 1200 1210 1220 1230
pF1KSD GLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSI
1060 1070 1080 1090 1100 1110
1240 1250 1260 1270 1280 1290
pF1KSD SPISLPCCLRILSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQA
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQA
1120 1130 1140 1150 1160 1170
1300 1310 1320 1330 1340 1350
pF1KSD VARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRR
1180 1190 1200 1210 1220 1230
1360 1370 1380 1390 1400
pF1KSD WTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 WTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
1240 1250 1260 1270 1280
>>XP_016874578 (OMIM: 607717) PREDICTED: tensin-2 isofor (1412 aa)
initn: 6684 init1: 6684 opt: 6694 Z-score: 2749.2 bits: 521.2 E(85289): 2.1e-146
Smith-Waterman score: 9697; 99.3% identity (99.3% similar) in 1393 aa overlap (26-1409:20-1412)
10 20 30 40 50 60
pF1KSD MKSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSC
:::::::::::::::::::::::::::::::::::
XP_016 MSLARPGWPSAHPLSPRLFPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSC
10 20 30 40 50
70 80 90 100 110 120
pF1KSD RVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD LDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD KRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD IVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD PLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD KGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEF
360 370 380 390 400 410
430 440 450 460 470
pF1KSD VFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDG---------SL
::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 VFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGAQAACRVGGSL
420 430 440 450 460 470
480 490 500 510 520 530
pF1KSD THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP
480 490 500 510 520 530
540 550 560 570 580 590
pF1KSD PPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRH
540 550 560 570 580 590
600 610 620 630 640 650
pF1KSD CSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGL
600 610 620 630 640 650
660 670 680 690 700 710
pF1KSD YPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLER
660 670 680 690 700 710
720 730 740 750 760 770
pF1KSD EAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYT
720 730 740 750 760 770
780 790 800 810 820 830
pF1KSD MCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSI
780 790 800 810 820 830
840 850 860 870 880 890
pF1KSD SPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLP
840 850 860 870 880 890
900 910 920 930 940 950
pF1KSD RSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQ
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KSD AGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPG
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KSD LRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQP
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
pF1KSD PLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVK
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
pF1KSD FVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWK
1140 1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
pF1KSD GDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRILSKDPL
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 GDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPL
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
pF1KSD EETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTP
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
pF1KSD AVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAK
1320 1330 1340 1350 1360 1370
1380 1390 1400
pF1KSD KPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
::::::::::::::::::::::::::::::::::::::
XP_016 KPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
1380 1390 1400 1410
>>XP_006719366 (OMIM: 607717) PREDICTED: tensin-2 isofor (1418 aa)
initn: 6684 init1: 6684 opt: 6694 Z-score: 2749.2 bits: 521.2 E(85289): 2.2e-146
Smith-Waterman score: 9852; 99.3% identity (99.3% similar) in 1418 aa overlap (1-1409:1-1418)
10 20 30 40 50 60
pF1KSD MKSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD RVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD IVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD PLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEF
370 380 390 400 410 420
430 440 450 460 470
pF1KSD VFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDG---------SL
::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_006 VFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGAQAACRVGGSL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 THTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD PPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRH
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD CSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD YPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLER
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD EAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYT
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD MCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSI
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD SPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD RSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQ
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KSD AGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPG
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KSD LRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQP
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KSD PLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVK
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KSD FVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWK
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KSD GDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRILSKDPL
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_006 GDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPL
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KSD EETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTP
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KSD AVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAK
1330 1340 1350 1360 1370 1380
1380 1390 1400
pF1KSD KPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
::::::::::::::::::::::::::::::::::::::
XP_006 KPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
1390 1400 1410
>>XP_016874577 (OMIM: 607717) PREDICTED: tensin-2 isofor (1418 aa)
initn: 6684 init1: 6684 opt: 6694 Z-score: 2749.2 bits: 521.2 E(85289): 2.2e-146
Smith-Waterman score: 9699; 98.9% identity (99.0% similar) in 1401 aa overlap (21-1409:18-1418)
10 20 30 40 50
pF1KSD MKSSGPVERLLRALGRRDSSRAASRP---RKAEPHSFREKVFRKKPPVCAVCKVTIDGTG
: :.:: :::::::::::::::::::::::::::::::
XP_016 MGWPGGSPCCCPAPPRPRPAGRPPQPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTG
10 20 30 40 50
60 70 80 90 100 110
pF1KSD VSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD SFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD LSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KSD LGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD NSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPA
300 310 320 330 340 350
360 370 380 390 400 410
pF1KSD LLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQAS
360 370 380 390 400 410
420 430 440 450 460
pF1KSD VEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDG--------
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGAQAACRVG
420 430 440 450 460 470
470 480 490 500 510 520
pF1KSD -SLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESP
480 490 500 510 520 530
530 540 550 560 570 580
pF1KSD GRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGL
540 550 560 570 580 590
590 600 610 620 630 640
pF1KSD SRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLS
600 610 620 630 640 650
650 660 670 680 690 700
pF1KSD EGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLR
660 670 680 690 700 710
710 720 730 740 750 760
pF1KSD LEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGC
720 730 740 750 760 770
770 780 790 800 810 820
pF1KSD SYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRA
780 790 800 810 820 830
830 840 850 860 870 880
pF1KSD GSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHS
840 850 860 870 880 890
890 900 910 920 930 940
pF1KSD TLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPP
900 910 920 930 940 950
950 960 970 980 990 1000
pF1KSD VSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTT
960 970 980 990 1000 1010
1010 1020 1030 1040 1050 1060
pF1KSD LPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGL
1020 1030 1040 1050 1060 1070
1070 1080 1090 1100 1110 1120
pF1KSD SQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQS
1080 1090 1100 1110 1120 1130
1130 1140 1150 1160 1170 1180
pF1KSD NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQ
1140 1150 1160 1170 1180 1190
1190 1200 1210 1220 1230 1240
pF1KSD PWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRILSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 PWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSK
1200 1210 1220 1230 1240 1250
1250 1260 1270 1280 1290 1300
pF1KSD DPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPR
1260 1270 1280 1290 1300 1310
1310 1320 1330 1340 1350 1360
pF1KSD PTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGF
1320 1330 1340 1350 1360 1370
1370 1380 1390 1400
pF1KSD VAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
:::::::::::::::::::::::::::::::::::::::::
XP_016 VAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
1380 1390 1400 1410
>>XP_006719365 (OMIM: 607717) PREDICTED: tensin-2 isofor (1428 aa)
initn: 6684 init1: 6684 opt: 6694 Z-score: 2749.2 bits: 521.2 E(85289): 2.2e-146
Smith-Waterman score: 9715; 98.5% identity (98.8% similar) in 1411 aa overlap (12-1409:18-1428)
10 20 30 40 50
pF1KSD MKSSGPVERLLRALG---RRDSS-RAASRPRKAEPHSFREKVFRKKPPVCAVCK
.::: :..: : : .:::::::::::::::::::::::::
XP_006 MDGGGVCVGRGDLLSSPQALGQLLRKESRPRRAMKPRKAEPHSFREKVFRKKPPVCAVCK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD VTIDGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTIDGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD QRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD DKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD CKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD LSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD CISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDE
370 380 390 400 410 420
420 430 440 450 460
pF1KSD RFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDG-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGA
430 440 450 460 470 480
470 480 490 500 510 520
pF1KSD --------SLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QAACRVGGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTT
490 500 510 520 530 540
530 540 550 560 570 580
pF1KSD EPAAESPGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EPAAESPGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVY
550 560 570 580 590 600
590 600 610 620 630 640
pF1KSD PGHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKR
610 620 630 640 650 660
650 660 670 680 690 700
pF1KSD RLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPT
670 680 690 700 710 720
710 720 730 740 750 760
pF1KSD AALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAG
730 740 750 760 770 780
770 780 790 800 810 820
pF1KSD EEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSP
790 800 810 820 830 840
830 840 850 860 870 880
pF1KSD GAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KSD EGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLS
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KSD PGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASP
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KSD RSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAA
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KSD SYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEP
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KSD PTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVA
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KSD TPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPC
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KSD CLRILSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSA
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSA
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KSD ALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGT
1330 1340 1350 1360 1370 1380
1370 1380 1390 1400
pF1KSD TSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
1390 1400 1410 1420
>>XP_016868027 (OMIM: 606825) PREDICTED: tensin-3 isofor (1559 aa)
initn: 3012 init1: 1286 opt: 1639 Z-score: 687.8 bits: 139.9 E(85289): 1.4e-31
Smith-Waterman score: 2570; 37.8% identity (58.8% similar) in 1449 aa overlap (24-1281:20-1430)
10 20 30 40 50
pF1KSD MKSSGPVERLLRALGRRDSSRAASRPRKAEP-------HSFREKVFRKKPPVCAVCKVTI
:: :. .: :.:..:.: :: ::.::: :
XP_016 MRLRALTPGPPGGFARGTRSRRRRRQPEELTSSLHAFKNKAF-KKSKVCGVCKQII
10 20 30 40 50
60 70 80 90 100 110
pF1KSD DGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRS
:: :.:::.:: . :.::::::. : :..: . :: ::. .:. : :.
XP_016 DGQGISCRACKYSCHKKCEAKVVIPCG----VQVRLEQAP-------GSS-TLSSSLCRD
60 70 80 90 100
120 130 140 150 160 170
pF1KSD TLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKY
: :.: ::. :::::.::::.:..::: .:. . .:.:....:.::: :.:
XP_016 KPLRPVILSPTMEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNY
110 120 130 140 150 160
180 190 200 210 220 230
pF1KSD LLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKG
:..::::::.:::.::::..: ::::::::::::.:.::::.:.::... :::::..:.:
XP_016 LVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KSD NKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSG
.::..::..:.:::....::.::::: ..:.:: .:::.. .::::.::....::::::
XP_016 GKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSG
230 240 250 260 270 280
300 310 320 330 340 350
pF1KSD SIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCIS
:..::.::::::.:.. : :. : .::::.::.:: :::::.:... .:...::
XP_016 SVKMNASPLFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIV
290 300 310 320 330 340
360 370 380 390 400 410
pF1KSD LEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFP
.::: :::::::: :::: :.. : ..::.:::: ...: :.: :..::.: :.:::
XP_016 IEPAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFP
350 360 370 380 390 400
420 430 440 450 460 470
pF1KSD FQASVEFVFSSSPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLT
..::.:::..::::.:: :: .: ::::::.: .:::::::. :.:: .
XP_016 DYGKVELVFSATPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENL------SADGEVL
410 420 430 440 450
480 490 500 510 520
pF1KSD HTRGPLDGSPYAQVQRPPRQTPPAPS-PEPPPP---P-----MLSVSSDSGHSS-TLTTE
::.::.::: ::.:.. . : :. :. : : ::::::::::. . :.
XP_016 HTQGPVDGSLYAKVRKKSSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTD
460 470 480 490 500 510
530 540 550
pF1KSD PAAE--SPG-RPPPTAAERQELDRLLGGCGVASGG-----------RGAG----------
. : .:: : .: :. :::.::.: :. . : . .:
XP_016 KTEERLAPGTRRGLSAQEKAELDQLLSGFGLEDPGSSLKEMTDARSKYSGTRHVVPAQVH
520 530 540 550 560 570
560 570 580 590
pF1KSD ---------RETAILDDEEQP--------TVGG-----GP---HLGVYPGHRPGLSRHCS
::: ::::: .: ..: :: ::: . :. :..
XP_016 VNGDAALKDRETDILDDE-MPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCHKS--SQNSL
580 590 600 610 620 630
600 610 620 630
pF1KSD CRQGY-----REPCG--VPNGGYYRPEGTLERRRLAYGGYEGS-PQ-------------G
.:. ..: : ::. : .: ::.: ..:. : . :: .
XP_016 LSDGFGSNVGEDPQGTLVPDLGLGM-DGPYERER-TFGSREPKQPQPLLRKPSVSAQMQA
640 650 660 670 680 690
640 650 660 670 680
pF1KSD YAEASMEKRRLCRS---LSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYP
:...:. . :. . : . :. . . . : :. .. .: .: : :
XP_016 YGQSSYSTQTWVRQQQMVVAHQYSFAPD----GEARLVSRCPADNPGLVQAQPRVP-LTP
700 710 720 730 740
690 700 710 720 730
pF1KSD CPACEEKLALPTAALYGLR-------------LEREAGEGWASEAGKPLLHPVRPGHP--
. ..:. .. : . : :. .. :: : :: :
XP_016 TRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTL
750 760 770 780 790 800
740 750 760 770 780
pF1KSD --------LPLLLPACGHHHAPMPDY-SCLKPPKAGEEGHEGCSYTMCPEGRYGHPGY-P
: :. :.: . . : : . .. . . .: : :
XP_016 DIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGP
810 820 830 840 850 860
790 800 810 820 830 840
pF1KSD ALVTYSYGGAVPSYCPAYGRVPH-SCGSPGEGRGYPSPGAHSP--RAG-SISPGSPPYPQ
. .: :... . : ::. . : :. . : : .. .:: . .:. ::.:.
XP_016 SRATGRQGSSAEQ--PLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPS
870 880 890 900 910 920
850 860 870 880 890
pF1KSD SRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTL---PRSPRDA
.. . : . :.. :. . ::: : : ...: : :: .
XP_016 PADVKETMTPGYPQDLDIIDGRILSSKESMCSTPAFPVS-PETPYVKTALRHPPFSPPEP
930 940 950 960 970 980
900 910 920 930 940
pF1KSD PCS--ASSELSG------PSTPLH----TSSPVQGKESTRRQDTRSPTS-----APTQRL
: : ::.. .: : : : . ::. : . : :. : : : . .
XP_016 PLSSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTI
990 1000 1010 1020 1030 1040
950 960 970 980
pF1KSD S---PGEALPPVSQAGTGKAPELPS------GSG-PE--PLAP--------SPVSPTFPP
: ::. :.: . :. ::: : ::. ::: :::
XP_016 SSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPP
1050 1060 1070 1080 1090 1100
990 1000 1010 1020 1030
pF1KSD S---SPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPL-----
: .: .: : . :. .: : .. :. :: : ::. :. :
XP_016 SELQAPFH-SHELSLAEPPDSLAP--PSSQAFLGFGTAPV-GSGLPPEEDLGALLANSHG
1110 1120 1130 1140 1150 1160
1040 1050 1060 1070
pF1KSD -TPVPSQMPWLVASPEPPQSSPTPAF----PLAASYDTNGLS--------QPPLPEKRHL
.:.:: .: :.:. .. . : : .:. . ::. :::::::..
XP_016 ASPTPS-IP-LTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRA
1170 1180 1190 1200 1210
1080 1090 1100 1110 1120 1130
pF1KSD PGPGQQPGPWGPEQA--SSPARGISHHVTFAPLLSD----NVPQTPEPPTQ-ESQSNVKF
.. : .: .. ::: : . . : .: : . .: : . .. :::
XP_016 SEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDSPGDKLVIVKF
1220 1230 1240 1250 1260 1270
1140 1150 1160 1170 1180 1190
pF1KSD VQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWK-
:::::::::: .::.::::.::::.::.:..::::::.::::::.::::::::. .
XP_016 VQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAMKVATPPPSVLQLNK
1280 1290 1300 1310 1320 1330
1200 1210 1220 1230 1240
pF1KSD --GDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRILSKD
:: ...:::::::: ::::..::: .:::::::.::: ::::.:..::: : : .:
XP_016 KAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERD
1340 1350 1360 1370 1380 1390
1250 1260 1270 1280 1290 1300
pF1KSD PLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRP
:::: :. : ..::.::.:::::.: ::
XP_016 PLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAIQKALSITLVQEPPP
1400 1410 1420 1430 1440 1450
1310 1320 1330 1340 1350 1360
pF1KSD TPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFV
XP_016 VSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQDRKWIKDGPSSKVFGFVA
1460 1470 1480 1490 1500 1510
>--
initn: 608 init1: 348 opt: 574 Z-score: 253.7 bits: 59.6 E(85289): 2.2e-07
Smith-Waterman score: 574; 66.9% identity (83.5% similar) in 127 aa overlap (1283-1409:1432-1557)
1260 1270 1280 1290 1300 1310
pF1KSD ETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPA
::: ::::: ::. .: : .: : :. .
XP_016 EIAESSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAIQKALSITLVQEPPPVST
1410 1420 1430 1440 1450 1460
1320 1330 1340 1350 1360 1370
pF1KSD VVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKK
::::::::::::::::::::::::::::::. : . :::::.: . :: .::.:::::.:
XP_016 VVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQDRKWIK-DGPSSKVFGFVARK
1470 1480 1490 1500 1510 1520
1380 1390 1400
pF1KSD PGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
:: .:::::::: ::.:::.:::.:..::..:. :
XP_016 QGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKV
1530 1540 1550
>>XP_011513780 (OMIM: 606825) PREDICTED: tensin-3 isofor (1534 aa)
initn: 3012 init1: 1286 opt: 1637 Z-score: 687.1 bits: 139.8 E(85289): 1.6e-31
Smith-Waterman score: 2565; 37.9% identity (59.1% similar) in 1434 aa overlap (32-1281:10-1405)
10 20 30 40 50 60
pF1KSD KSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSCR
:.:..:.: :: ::.::: ::: :.:::
XP_011 MPEELTSSLHAFKNKAF-KKSKVCGVCKQIIDGQGISCR
10 20 30
70 80 90 100 110 120
pF1KSD VCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSL
.:: . :.::::::. : :..: . :: ::. .:. : :. : :
XP_011 ACKYSCHKKCEAKVVIPCG----VQVRLEQAP-------GSS-TLSSSLCRDKPLRPVIL
40 50 60 70 80
130 140 150 160 170 180
pF1KSD DPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEK
.: ::. :::::.::::.:..::: .:. . .:.:....:.::: :.::..:::::
XP_011 SPTMEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEK
90 100 110 120 130 140
190 200 210 220 230 240
pF1KSD RHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVI
:.:::.::::..: ::::::::::::.:.::::.:.::... :::::..:.:.::..::.
XP_011 RYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVV
150 160 170 180 190 200
250 260 270 280 290 300
pF1KSD VSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSP
.:.:::....::.::::: ..:.:: .:::.. .::::.::....:::::::..::.::
XP_011 ISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASP
210 220 230 240 250 260
310 320 330 340 350 360
pF1KSD LFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLK
::::.:.. : :. : .::::.::.:: :::::.:... .:...:: .::: :::
XP_011 LFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLK
270 280 290 300 310 320
370 380 390 400 410 420
pF1KSD GDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFV
::::: :::: :.. : ..::.:::: ...: :.: :..::.: :.::: ..::.:
XP_011 GDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELV
330 340 350 360 370 380
430 440 450 460 470 480
pF1KSD FSSSPEKIKGSTP-RNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDG
::..::::.:: :: .: ::::::.: .:::::::. :.:: . ::.::.::
XP_011 FSATPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENL------SADGEVLHTQGPVDG
390 400 410 420 430 440
490 500 510 520
pF1KSD SPYAQVQRPPRQTPPAPS-PEPPPP---P-----MLSVSSDSGHSS-TLTTEPAAE--SP
: ::.:.. . : :. :. : : ::::::::::. . :. . : .:
XP_011 SLYAKVRKKSSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAP
450 460 470 480 490 500
530 540 550
pF1KSD G-RPPPTAAERQELDRLLGGCGVASGG-----------RGAG------------------
: : .: :. :::.::.: :. . : . .:
XP_011 GTRRGLSAQEKAELDQLLSGFGLEDPGSSLKEMTDARSKYSGTRHVVPAQVHVNGDAALK
510 520 530 540 550 560
560 570 580 590
pF1KSD -RETAILDDEEQP--------TVGG-----GP---HLGVYPGHRPGLSRHCSCRQGY---
::: ::::: .: ..: :: ::: . :. :.. .:.
XP_011 DRETDILDDE-MPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCHKS--SQNSLLSDGFGSN
570 580 590 600 610
600 610 620 630 640
pF1KSD --REPCG--VPNGGYYRPEGTLERRRLAYGGYEGS-PQ-------------GYAEASMEK
..: : ::. : .: ::.: ..:. : . :: .:...:.
XP_011 VGEDPQGTLVPDLGLGM-DGPYERER-TFGSREPKQPQPLLRKPSVSAQMQAYGQSSYST
620 630 640 650 660 670
650 660 670 680 690
pF1KSD RRLCRS---LSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKL
. :. . : . :. :. . . : :. .. .: .: : : . ..
XP_011 QTWVRQQQMVVAHQYSFAPD-GE---ARLVSRCPADNPGLVQAQPRVP-LTPTRGTSSRV
680 690 700 710 720 730
700 710 720 730
pF1KSD ALPTAALYGLR-------------LEREAGEGWASEAGKPLLHPVRPGHP----------
:. .. : . : :. .. :: : :: :
XP_011 AVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQ
740 750 760 770 780 790
740 750 760 770 780 790
pF1KSD LPLLLPACGHHHAPMPDY-SCLKPPKAGEEGHEGCSYTMCPEGRYGHPGY-PALVTYSYG
: :. :.: . . : : . .. . . .: : :. .: :
XP_011 LNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQG
800 810 820 830 840 850
800 810 820 830 840
pF1KSD GAVPSYCPAYGRVPH-SCGSPGEGRGYPSPGAHSP--RAG-SISPGSPPYPQSRKLSYEI
... . : ::. . : :. . : : .. .:: . .:. ::.:. .. .
XP_011 SSAEQ--PLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETM
860 870 880 890 900
850 860 870 880 890 900
pF1KSD PTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTL---PRSPRDAPCS--ASS
: . :.. :. . ::: : : ...: : :: . : : ::.
XP_011 TPGYPQDLDIIDGRILSSKESMCSTPAFPVS-PETPYVKTALRHPPFSPPEPPLSSPASQ
910 920 930 940 950 960
910 920 930 940
pF1KSD ELSG------PSTPLH----TSSPVQGKESTRRQDTRSPTS-----APTQRLS---PGEA
. .: : : : . ::. : . : :. : : : . .: ::.
XP_011 HKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQR
970 980 990 1000 1010 1020
950 960 970 980
pF1KSD LPPVSQAGTGKAPELPS------GSG-PE--PLAP--------SPVSPTFPPS---SPSD
:.: . :. ::: : ::. ::: :::: .:
XP_011 RESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFH
1030 1040 1050 1060 1070 1080
990 1000 1010 1020 1030
pF1KSD WPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPL------TPVPSQM
.: : . :. .: : .. :. :: : ::. :. : .:.:: .
XP_011 -SHELSLAEPPDSLAP--PSSQAFLGFGTAPV-GSGLPPEEDLGALLANSHGASPTPS-I
1090 1100 1110 1120 1130 1140
1040 1050 1060 1070 1080
pF1KSD PWLVASPEPPQSSPTPAF----PLAASYDTNGLS--------QPPLPEKRHLPGPGQQPG
: :.:. .. . : : .:. . ::. :::::::.. .. :
XP_011 P-LTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLG
1150 1160 1170 1180 1190 1200
1090 1100 1110 1120 1130 1140
pF1KSD PWGPEQA--SSPARGISHHVTFAPLLSD----NVPQTPEPPTQ-ESQSNVKFVQDTSKFW
.: .. ::: : . . : .: : . .: : . .. :::::::::::
XP_011 SVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDSPGDKLVIVKFVQDTSKFW
1210 1220 1230 1240 1250 1260
1150 1160 1170 1180 1190
pF1KSD YKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWK---GDPVEQ
:: .::.::::.::::.::.:..::::::.::::::.::::::::. . :: ...
XP_011 YKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAMKVATPPPSVLQLNKKAGDLANE
1270 1280 1290 1300 1310 1320
1200 1210 1220 1230 1240 1250
pF1KSD LVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRILSKDPLEETPEA
:::::::: ::::..::: .:::::::.::: ::::.:..::: : : .::::: :.
XP_011 LVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAES
1330 1340 1350 1360 1370 1380
1260 1270 1280 1290 1300 1310
pF1KSD PVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFK
: ..::.::.:::::.: ::
XP_011 SPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAIQKALSITLVQEPPPVSTVVHFK
1390 1400 1410 1420 1430 1440
>--
initn: 608 init1: 348 opt: 574 Z-score: 253.7 bits: 59.6 E(85289): 2.1e-07
Smith-Waterman score: 574; 66.9% identity (83.5% similar) in 127 aa overlap (1283-1409:1407-1532)
1260 1270 1280 1290 1300 1310
pF1KSD ETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPA
::: ::::: ::. .: : .: : :. .
XP_011 EIAESSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAIQKALSITLVQEPPPVST
1380 1390 1400 1410 1420 1430
1320 1330 1340 1350 1360 1370
pF1KSD VVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKK
::::::::::::::::::::::::::::::. : . :::::.: . :: .::.:::::.:
XP_011 VVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQDRKWIK-DGPSSKVFGFVARK
1440 1450 1460 1470 1480 1490
1380 1390 1400
pF1KSD PGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK
:: .:::::::: ::.:::.:::.:..::..:. :
XP_011 QGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKV
1500 1510 1520 1530
1409 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 04:53:52 2016 done: Thu Nov 3 04:53:55 2016
Total Scan time: 20.550 Total Display time: 0.660
Function used was FASTA [36.3.4 Apr, 2011]