Result of FASTA (ccds) for
pF1KSDA1088
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1088, 1400 aa
1>>>pF1KSDA1088 1400 - 1400 aa - 1400 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1406+/-0.000979; mu= 12.2260+/- 0.059
mean_var=192.8594+/-38.996, 0's: 0 Z-trim(112.3): 20 B-trim: 121 in 1/52
Lambda= 0.092354
statistics sampled from 13068 (13083) to 13068 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.402), width: 16
Scan time: 6.210
The best scores are: opt bits E(32554)
CCDS63331.1 RTEL1 gene_id:51750|Hs108|chr20 (1300) 8886 1197.5 0
CCDS13531.1 RTEL1 gene_id:51750|Hs108|chr20 (1219) 8253 1113.1 0
CCDS13530.3 RTEL1 gene_id:51750|Hs108|chr20 (1243) 7372 995.8 0
CCDS74751.1 RTEL1 gene_id:51750|Hs108|chr20 ( 996) 6748 912.5 0
CCDS11631.1 BRIP1 gene_id:83990|Hs108|chr17 (1249) 940 138.8 9.6e-32
CCDS58224.1 DDX11 gene_id:1663|Hs108|chr12 ( 880) 547 86.3 4.3e-16
CCDS41767.1 DDX11 gene_id:1663|Hs108|chr12 ( 906) 547 86.3 4.4e-16
CCDS33049.1 ERCC2 gene_id:2068|Hs108|chr19 ( 760) 517 82.2 6.1e-15
>>CCDS63331.1 RTEL1 gene_id:51750|Hs108|chr20 (1300 aa)
initn: 9059 init1: 8886 opt: 8886 Z-score: 6404.9 bits: 1197.5 E(32554): 0
Smith-Waterman score: 8886; 99.8% identity (100.0% similar) in 1300 aa overlap (1-1300:1-1300)
10 20 30 40 50 60
pF1KSD MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 QVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 KSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 DLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 ADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 TKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD YKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 YKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 TLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD LGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 LGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD TISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 TISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKM
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD QFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 QFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD RAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 RAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD GPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 GPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEH
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD SEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 SEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD VAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 VAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD KQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 KQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD HLNQGRPHLSPRPPPTGDPGSHPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLL
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
CCDS63 HLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD AALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 AALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPY
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD GPSQSSGPPHGPAASEWGEPHGRDIAGQQATGAPGGPLSAGCVCQGCGAEDVVPFQCPAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 GPSQSSGPPHGPAASEWGEPHGRDIAGQQATGAPGGPLSAGCVCQGCGAEDVVPFQCPAC
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD DFQRCQACWQRHLQASRMCPACHTASRKQSVMQVFWPEPHKDHEGAGGARPVAAVPGVGA
:::::::::::::::::::::::::::::::::::::::.
CCDS63 DFQRCQACWQRHLQASRMCPACHTASRKQSVMQVFWPEPQ
1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KSD ACPAAGAGCTRSGRNTHLPLAGRRDRGAAGVRPVPPRHLCAAAVPPRQPHDVWPVSTAPL
>>CCDS13531.1 RTEL1 gene_id:51750|Hs108|chr20 (1219 aa)
initn: 8253 init1: 8253 opt: 8253 Z-score: 5949.5 bits: 1113.1 E(32554): 0
Smith-Waterman score: 8253; 99.9% identity (100.0% similar) in 1218 aa overlap (1-1218:1-1218)
10 20 30 40 50 60
pF1KSD MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 ADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 TKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD YKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 TLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD LGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD TISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 TISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKM
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD QFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD RAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD GPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEH
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD SEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFM
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD VAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD KQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD HLNQGRPHLSPRPPPTGDPGSHPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLL
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
CCDS13 HLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD AALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 AALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPY
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDA
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD GPSQSSGPPHGPAASEWGEPHGRDIAGQQATGAPGGPLSAGCVCQGCGAEDVVPFQCPAC
::::::::::::::::::
CCDS13 GPSQSSGPPHGPAASEWGL
1210
>>CCDS13530.3 RTEL1 gene_id:51750|Hs108|chr20 (1243 aa)
initn: 7372 init1: 7372 opt: 7372 Z-score: 5315.0 bits: 995.8 E(32554): 0
Smith-Waterman score: 8195; 98.0% identity (98.1% similar) in 1242 aa overlap (1-1218:1-1242)
10 20 30 40 50 60
pF1KSD MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 EHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLT
70 80 90 100 110 120
130 140 150
pF1KSD QVINELRNTSYR------------------------PKVCVLGSREQLCIHPEVKKQESN
:::::::::::: ::::::::::::::::::::::::
CCDS13 QVINELRNTSYRSRCRATLWVLETAPPRPTVLSPTRPKVCVLGSREQLCIHPEVKKQESN
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD HLQIHLCRKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 HLQIHLCRKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLK
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD QQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD DVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD DDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADII
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD QIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYW
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD CFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 CFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVV
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD PRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRAR
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD DLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDT
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD NGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIG
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD RVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTM
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD PAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSL
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD CVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 CVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRK
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD KIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLG
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD PLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQRAQPVLDP
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KSD TGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSHPQWGSGVPRAGKQG
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
CCDS13 TGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVPRAGKQG
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KSD QHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRF
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KSD SMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGK
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KSD TQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGEPHGRDIAGQQATGAPGG
::::::::::::::::::::::::::::::::::::::::::
CCDS13 TQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGL
1210 1220 1230 1240
1240 1250 1260 1270 1280 1290
pF1KSD PLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQASRMCPACHTASRKQSVMQVFW
>>CCDS74751.1 RTEL1 gene_id:51750|Hs108|chr20 (996 aa)
initn: 6748 init1: 6748 opt: 6748 Z-score: 4866.9 bits: 912.5 E(32554): 0
Smith-Waterman score: 6748; 99.9% identity (100.0% similar) in 995 aa overlap (224-1218:1-995)
200 210 220 230 240 250
pF1KSD IEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAH
::::::::::::::::::::::::::::::
CCDS74 MPYNYLLDAKSRRAHNIDLKGTVVIFDEAH
10 20 30
260 270 280 290 300 310
pF1KSD NVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 NVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELE
40 50 60 70 80 90
320 330 340 350 360 370
pF1KSD DIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 DIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQII
100 110 120 130 140 150
380 390 400 410 420 430
pF1KSD QHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 QHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDAGHRR
160 170 180 190 200 210
440 450 460 470 480 490
pF1KSD TAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQ
220 230 240 250 260 270
500 510 520 530 540 550
pF1KSD IPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 IPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVP
280 290 300 310 320 330
560 570 580 590 600 610
pF1KSD YGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 YGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPG
340 350 360 370 380 390
620 630 640 650 660 670
pF1KSD STGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 STGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAG
400 410 420 430 440 450
680 690 700 710 720 730
pF1KSD GQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 GQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVR
460 470 480 490 500 510
740 750 760 770 780 790
pF1KSD VYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLD
520 530 540 550 560 570
800 810 820 830 840 850
pF1KSD LHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEHSEQRAGSPGEEQA
580 590 600 610 620 630
860 870 880 890 900 910
pF1KSD HSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 HSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQANFA
640 650 660 670 680 690
920 930 940 950 960 970
pF1KSD TFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTG
700 710 720 730 740 750
980 990 1000 1010 1020 1030
pF1KSD RGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRP
760 770 780 790 800 810
1040 1050 1060 1070 1080 1090
pF1KSD PPTGDPGSHPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLD
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PPTGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLD
820 830 840 850 860 870
1100 1110 1120 1130 1140 1150
pF1KSD KVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 KVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERL
880 890 900 910 920 930
1160 1170 1180 1190 1200 1210
pF1KSD AVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 AVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPA
940 950 960 970 980 990
1220 1230 1240 1250 1260 1270
pF1KSD ASEWGEPHGRDIAGQQATGAPGGPLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHL
:::::
CCDS74 ASEWGL
>>CCDS11631.1 BRIP1 gene_id:83990|Hs108|chr17 (1249 aa)
initn: 1248 init1: 301 opt: 940 Z-score: 683.4 bits: 138.8 E(32554): 9.6e-32
Smith-Waterman score: 1155; 32.1% identity (61.9% similar) in 761 aa overlap (104-831:241-957)
80 90 100 110 120 130
pF1KSD ERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRP
. :::: ...:::.:..:. ::: :.:
CCDS11 PGHCSRCCCSTKQGNSQESSNTIKKDHTGKSKIPKIYFGTRTHKQIAQITRELRRTAYSG
220 230 240 250 260 270
140 150 160 170 180
pF1KSD -KVCVLGSREQLCIHPEVKKQ-ESNHLQIHLCRKKVASRSCHFYNNVEEKSLEQELAS--
. .:.::.. :.:::: . . :. ..: : ..::.::..:.. : .. : .
CCDS11 VPMTILSSRDHTCVHPEVVGNFNRNEKCMELLDGK-NGKSCYFYHGVHKISDQHTLQTFQ
280 290 300 310 320
190 200 210 220 230 240
pF1KSD ---PILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTV
:::.::. :.: ..:::: .:.: :.::::: ::::::::. :.. ...:: :
CCDS11 GMCKAWDIEELVSLGKKLKACPYYTARELIQDADIIFCPYNYLLDAQIRESMDLNLKEQV
330 340 350 360 370 380
250 260 270 280 290 300
pF1KSD VIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQGEPHPEFSA-----
::.:::::.: .::::...: .: . : .:...... . .. ::
CCDS11 VILDEAHNIEDCARESASYSVTEVQLRFARDELDSMVNNNIRK-KDHEPLRAVCCSLINW
390 400 410 420 430 440
310 320 330 340 350
pF1KSD -DSPSPGL-NMELEDIAKL----KMILLRLEGAIDAVELP---GDDSGVTKPGSYIFELF
.. . : . . :. :. .:.: . .: .. .: : :.: . : ..
CCDS11 LEANAEYLVERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIY
450 460 470 480 490 500
360 370 380 390 400
pF1KSD A-----EAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEG
. :. . . .: .: .....: . . :.. :.: :: ..: ..
CCDS11 GKEEAREVPVISASTQIMLKGLFMVLDYLFRQNSRFADD---YKIA--IQQTYSWT-NQI
510 520 530 540 550 560
410 420 430 440 450 460
pF1KSD SPGSPAGLGALQSYKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHEL
. .. :: .: . : .:. :. ::.. ::..::..:. .. .
CCDS11 DISDKNGLLVLPKNK---------KRSRQK------TAVH----VLNFWCLNPAVAFSD-
570 580 590 600
470 480 490 500 510 520
pF1KSD VRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSS
. :....::::::.:..::. :. . : . :: ::: . :.:::.. :: : .: .
CCDS11 INGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQVWVGTIGSGPKGRNLCA
610 620 630 640 650 660
530 540 550 560 570 580
pF1KSD AFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKP
.:. . : . .: : .. ..: :.: :.::: ..:: : : . : ...: .:
CCDS11 TFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKT
670 680 690 700 710 720
590 600 610 620 630 640
pF1KSD LFVEPRS--KGSFSETISAYYARVAAPG-STGATFLAVCRGKASEGLDFSDTNGRGVIVT
..:::.. : .:.: ...:: . : . :: ..::::::.:::::::: :.:.::.
CCDS11 VIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITI
730 740 750 760 770 780
650 660 670 680 690 700
pF1KSD GLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQD
:.:.: : .: :: :. :. . : .: :..::. :: ::.:::.:: ::::.:
CCDS11 GIPFPNVKDLQVELKRQYNDHHSKLRG----LLPGRQWYEIQAYRALNQALGRCIRHRND
790 800 810 820 830
710 720 730 740 750 760
pF1KSD YGAVFLCDHRFAFADAR--AQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPR
.::..: : :: .: . : .::: ... ...: .....:.: . .... .
CCDS11 WGALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNV----
840 850 860 870 880 890
770 780 790 800 810 820
pF1KSD ATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAG-DPESSLCVEYE
:.. . ... .: : . . : : :. : :: . :...::.
CCDS11 ----SIKDRTNIQDNESTLEVTSLKYSTSPYL----LEAASHLSPENFVEDEAKICVQEL
900 910 920 930 940
830 840 850 860 870 880
pF1KSD QEP-VPARQRPRGLLAALEHSEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRL
: : . ... :
CCDS11 QCPKIITKNSPLPSSIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRVSWSSFN
950 960 970 980 990 1000
>>CCDS58224.1 DDX11 gene_id:1663|Hs108|chr12 (880 aa)
initn: 903 init1: 209 opt: 547 Z-score: 402.4 bits: 86.3 E(32554): 4.3e-16
Smith-Waterman score: 826; 27.8% identity (56.9% similar) in 698 aa overlap (106-750:200-874)
80 90 100 110 120 130
pF1KSD AQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRPKV
: :: : :::::::.: ..:.... . :
CCDS58 ELVLAEYESDEEKKVASRVDEDEDDLEEEHITKIYYCSRTHSQLAQFVHEVKKSPFGKDV
170 180 190 200 210 220
140 150 160 170
pF1KSD CV--LGSREQLCIHPEVKKQESNHLQIHLC---------------------RKKVASRSC
. ::::..::.. .::. : .: : :.. . .:
CCDS58 RLVSLGSRQNLCVNEDVKSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAAC
230 240 250 260 270 280
180 190 200 210 220 230
pF1KSD HFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDA
:::. . :..: . . :.:.:. :.. :.:::: :: :... .::..:: :
CCDS58 PFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHA
290 300 310 320 330 340
240 250 260 270 280 290
pF1KSD KSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQ
.:.: .: :. :::.:::::. : .:. .. ....:
CCDS58 ATRQAAGIRLQDQVVIIDEAHNLI--------------DTITGMHSVE------VSGSQL
350 360 370 380
300 310 320 330 340
pF1KSD GEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDA----VELPGDDSGVTKPGSY-
. : .. : .. ... ::.:: :: . . .. . ..... :.
CCDS58 CQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGTEL
390 400 410 420 430 440
350 360 370 380 390 400
pF1KSD --IFELFAEAQIT----FQT-KGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVF
: ... ..:: :.. . : . ... . .. : :. .. ::: . :..
CCDS58 KTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGAVFSSREQPKLAGFQQFLQ
450 460 470 480 490 500
410 420 430 440 450
pF1KSD SVDP--SEG--SPGSPAGLGALQ--SYKVHIHPDAGHRRTA-QRSDAWSTTAARKRGKVL
:..: .:. .:.. . ..:. : .::. . :: : . . . . ..:
CCDS58 SLQPRTTEALAAPADESQASTLRPASPLMHIQGFLAALTTANQDGRVILSRQGSLSQSTL
510 520 530 540 550 560
460 470 480 490 500
pF1KSD SYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEM------QIPFPVCLENPHIID
.. ..:. . ..:.. :......::. :::.: .. . : . :.:
CCDS58 KFLLLNPAVHFAQVVKE-CRAVVIAGGTMQPVSDFRQQLLACAGVEAERVVEFSCGHVIP
570 580 590 600 610 620
510 520 530 540 550 560
pF1KSD KHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVME
.: :. : .. : .:..: . .. .:. : :. ::: :.. ::::: ..
CCDS58 PDNILPLVICSGISNQPLEFTFQKRELPQMMDEVGRILCNLCGVVPGGVVCFFPSYEYLR
630 640 650 660 670 680
570 580 590 600 610 620
pF1KSD KSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGS-----TGATFLAV
. :. : .. : : .: ::.: . ... :: . : :. ::: .:.:
CCDS58 QVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSRCIQACGQERGQVTGALLLSV
690 700 710 720 730 740
630 640 650 660 670 680
pF1KSD CRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEW
:: :::..:::. :: :...:.:.: . .. :: .::. . : :: :.
CCDS58 VGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPR--APGQAPPGKAL
750 760 770 780 790 800
690 700 710 720 730 740
pF1KSD YRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVI
.. .::::.:::.:::..:...: : :.:.: . :.::.:.: .:.: .:: .:
CCDS58 VENLCMKAVNQSIGRAIRHQKDFASVVLLDQRYARPPVLAKLPAWIRARVEVKATFGPAI
810 820 830 840 850 860
750 760 770 780 790 800
pF1KSD RDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQR
: .: :
CCDS58 AAVQKFHREKSASS
870 880
>>CCDS41767.1 DDX11 gene_id:1663|Hs108|chr12 (906 aa)
initn: 964 init1: 209 opt: 547 Z-score: 402.3 bits: 86.3 E(32554): 4.4e-16
Smith-Waterman score: 826; 27.8% identity (56.9% similar) in 698 aa overlap (106-750:226-900)
80 90 100 110 120 130
pF1KSD AQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRPKV
: :: : :::::::.: ..:.... . :
CCDS41 ELVLAEYESDEEKKVASRVDEDEDDLEEEHITKIYYCSRTHSQLAQFVHEVKKSPFGKDV
200 210 220 230 240 250
140 150 160 170
pF1KSD CV--LGSREQLCIHPEVKKQESNHLQIHLC---------------------RKKVASRSC
. ::::..::.. .::. : .: : :.. . .:
CCDS41 RLVSLGSRQNLCVNEDVKSLGSVQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAAC
260 270 280 290 300 310
180 190 200 210 220 230
pF1KSD HFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDA
:::. . :..: . . :.:.:. :.. :.:::: :: :... .::..:: :
CCDS41 PFYNHEQMGLLRDEALAEVKDMEQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHA
320 330 340 350 360 370
240 250 260 270 280 290
pF1KSD KSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVIDQVLEEQTKAAQQ
.:.: .: :. :::.:::::. : .:. .. ....:
CCDS41 ATRQAAGIRLQDQVVIIDEAHNLI--------------DTITGMHSVE------VSGSQL
380 390 400 410
300 310 320 330 340
pF1KSD GEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDA----VELPGDDSGVTKPGSY-
. : .. : .. ... ::.:: :: . . .. . ..... :.
CCDS41 CQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAVLGGNIKQNPNTQSLSQTGTEL
420 430 440 450 460 470
350 360 370 380 390 400
pF1KSD --IFELFAEAQIT----FQT-KGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVF
: ... ..:: :.. . : . ... . .. : :. .. ::: . :..
CCDS41 KTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTERYGAVFSSREQPKLAGFQQFLQ
480 490 500 510 520 530
410 420 430 440 450
pF1KSD SVDP--SEG--SPGSPAGLGALQ--SYKVHIHPDAGHRRTA-QRSDAWSTTAARKRGKVL
:..: .:. .:.. . ..:. : .::. . :: : . . . . ..:
CCDS41 SLQPRTTEALAAPADESQASTLRPASPLMHIQGFLAALTTANQDGRVILSRQGSLSQSTL
540 550 560 570 580 590
460 470 480 490 500
pF1KSD SYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEM------QIPFPVCLENPHIID
.. ..:. . ..:.. :......::. :::.: .. . : . :.:
CCDS41 KFLLLNPAVHFAQVVKE-CRAVVIAGGTMQPVSDFRQQLLACAGVEAERVVEFSCGHVIP
600 610 620 630 640 650
510 520 530 540 550 560
pF1KSD KHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVME
.: :. : .. : .:..: . .. .:. : :. ::: :.. ::::: ..
CCDS41 PDNILPLVICSGISNQPLEFTFQKRELPQMMDEVGRILCNLCGVVPGGVVCFFPSYEYLR
660 670 680 690 700 710
570 580 590 600 610 620
pF1KSD KSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGS-----TGATFLAV
. :. : .. : : .: ::.: . ... :: . : :. ::: .:.:
CCDS41 QVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQVLLAYSRCIQACGQERGQVTGALLLSV
720 730 740 750 760 770
630 640 650 660 670 680
pF1KSD CRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEW
:: :::..:::. :: :...:.:.: . .. :: .::. . : :: :.
CCDS41 VGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAELQEKMAYLDQTLPR--APGQAPPGKAL
780 790 800 810 820 830
690 700 710 720 730 740
pF1KSD YRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVI
.. .::::.:::.:::..:...: : :.:.: . :.::.:.: .:.: .:: .:
CCDS41 VENLCMKAVNQSIGRAIRHQKDFASVVLLDQRYARPPVLAKLPAWIRARVEVKATFGPAI
840 850 860 870 880 890
750 760 770 780 790 800
pF1KSD RDVAQFFRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQR
: .: :
CCDS41 AAVQKFHREKSASS
900
>>CCDS33049.1 ERCC2 gene_id:2068|Hs108|chr19 (760 aa)
initn: 790 init1: 154 opt: 517 Z-score: 381.7 bits: 82.2 E(32554): 6.1e-15
Smith-Waterman score: 729; 26.0% identity (53.5% similar) in 792 aa overlap (3-762:2-730)
10 20 30 40 50
pF1KSD MPKIVLNGVTVDFPFQP-YKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAW
:. ..:. : ::.. : : :: .. . :. : .:.:: :.:::::. :: .:.
CCDS33 MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAY
10 20 30 40 50
60 70 80 90 100 110
pF1KSD REHLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQL
.:: .: .. :.:: ::: ..
CCDS33 --------------QRA----YP---------------------LEVTKLIYCSRTVPEI
60 70 80
120 130 140 150 160
pF1KSD TQVINELRN--TSYRP----KVCVLG----SREQLCIHPEVKKQESNHLQIHLCRKKVAS
.::.:::. . :. :. :: ::..::::::: . .. :.. .::
CCDS33 EKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTAS
90 100 110 120 130 140
170 180 190 200 210
pF1KSD --RS----------CHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQ
:. :.::.. . .. : : . : ...:: : .. :::.:.:
CCDS33 YVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSIL
150 160 170 180 190 200
220 230 240 250 260 270
pF1KSD QADIIFMPYNYLLDAKSRRAHNIDL-KGTVVIFDEAHNVEKMCEESASFDLTPHDLASGL
.:... . :.:::: : . .: . .::.::::::....: .: : .:: . :
CCDS33 HANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQ
210 220 230 240 250 260
280 290 300 310 320 330
pF1KSD DVIDQVLEEQTKAAQQGEPHPEFSADSPSPGL---NMELEDIAKLKMILLRLEGAIDAVE
.. . . . . : . . :: . : :.: .: : .::
CCDS33 GNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAV-
270 280 290 300 310
340 350 360 370 380 390
pF1KSD LPGDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGL--QK
::. . . ... .:. .. .... . .: ... :: :. . . . ..
CCDS33 -PGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAER
320 330 340 350 360 370
400 410 420 430 440 450
pF1KSD LADIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDA-GHRRTAQRSDAWSTTAARKRG
: .... . .: .. :: : : .. . . : : . : . : : .
CCDS33 LRSLLHTLEITDLADFSP-----LTLLANFATLVSTYAKGFTIIIEPFDDRTPTIA---N
380 390 400 410 420 430
460 470 480 490 500
pF1KSD KVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLEN-PHIIDKH
.: . :.. . ... : . .:.:.:::::.:.. . ... :: . . . .
CCDS33 PILHFSCMDASLAIKP-VFERFQSVIITSGTLSPLDIYPKILDF-HPVTMATFTMTLARV
440 450 460 470 480
510 520 530 540 550 560
pF1KSD QIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFFPSYPVMEKS
. .. :: : . .:: :. : . . . :. : ... ::: :.. :: :: ::..
CCDS33 CLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMEST
490 500 510 520 530 540
570 580 590 600 610 620
pF1KSD LEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASE
. : . . .... : ::.: .. . : .. : : .. :: .:.: :::.::
CCDS33 VASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQE--ACENGRGAILLSVARGKVSE
550 560 570 580 590 600
630 640 650 660 670 680
pF1KSD GLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQF-LSGQEWYRQQAS
:.:: ::.::. :.:: .. . ....: . :: . ... .:
CCDS33 GIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRD---------QFQIRENDFLTFDAM
610 620 630 640 650
690 700 710 720 730 740
pF1KSD RAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQF
: . : .::.:: . ::: . . :.::: .: :..:: :.. :. . :.. .. . .:
CCDS33 RHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHL-TDANLNLTVDEGVQV
660 670 680 690 700 710
750 760 770 780 790 800
pF1KSD FRVAERTMPAPAPRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPA
. : : : :
CCDS33 AKYFLRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL
720 730 740 750 760
1400 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 04:56:30 2016 done: Thu Nov 3 04:56:31 2016
Total Scan time: 6.210 Total Display time: 0.440
Function used was FASTA [36.3.4 Apr, 2011]