Result of FASTA (omim) for
pF1KSDA1099
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1099, 804 aa
1>>>pF1KSDA1099 804 - 804 aa - 804 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.3823+/-0.000477; mu= 7.3785+/- 0.030
mean_var=236.3706+/-47.364, 0's: 0 Z-trim(117.6): 257 B-trim: 1058 in 2/56
Lambda= 0.083421
statistics sampled from 29342 (29659) to 29342 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.348), width: 16
Scan time: 14.070
The best scores are: opt bits E(85289)
NP_055729 (OMIM: 608651) arf-GAP with GTPase, ANK ( 804) 5290 650.7 7.4e-186
XP_005246116 (OMIM: 608651) PREDICTED: arf-GAP wit ( 808) 5272 648.5 3.3e-185
XP_011508851 (OMIM: 608651) PREDICTED: arf-GAP wit (1073) 4932 607.7 8.4e-173
XP_011508850 (OMIM: 608651) PREDICTED: arf-GAP wit (1098) 2896 362.7 4.9e-99
NP_001032208 (OMIM: 608651) arf-GAP with GTPase, A ( 857) 2877 360.3 2e-98
XP_006712298 (OMIM: 608651) PREDICTED: arf-GAP wit ( 882) 2877 360.3 2.1e-98
XP_006712297 (OMIM: 608651) PREDICTED: arf-GAP wit ( 886) 2859 358.1 9.3e-98
XP_006712300 (OMIM: 608651) PREDICTED: arf-GAP wit (1147) 2537 319.5 5.2e-86
XP_006712302 (OMIM: 608651) PREDICTED: arf-GAP wit (1151) 2519 317.3 2.3e-85
XP_011508849 (OMIM: 608651) PREDICTED: arf-GAP wit (1126) 2424 305.9 6.3e-82
NP_001231817 (OMIM: 608651) arf-GAP with GTPase, A ( 405) 2269 286.8 1.3e-76
XP_016867221 (OMIM: 616813) PREDICTED: arf-GAP wit ( 630) 2086 265.0 7.4e-70
XP_016858771 (OMIM: 608651) PREDICTED: arf-GAP wit (1106) 2074 263.8 3e-69
NP_001036000 (OMIM: 616813) arf-GAP with GTPase, A ( 396) 1759 225.4 3.8e-58
XP_005250000 (OMIM: 616813) PREDICTED: arf-GAP wit ( 565) 1602 206.7 2.4e-52
XP_011514082 (OMIM: 616813) PREDICTED: arf-GAP wit ( 683) 1602 206.8 2.7e-52
NP_114152 (OMIM: 616813) arf-GAP with GTPase, ANK ( 911) 1602 206.9 3.3e-52
NP_001295233 (OMIM: 616813) arf-GAP with GTPase, A ( 343) 1515 196.0 2.4e-49
NP_001295234 (OMIM: 616813) arf-GAP with GTPase, A ( 576) 1504 194.9 8.5e-49
XP_016867224 (OMIM: 616813) PREDICTED: arf-GAP wit ( 462) 1429 185.8 3.8e-46
XP_016867222 (OMIM: 616813) PREDICTED: arf-GAP wit ( 527) 1429 185.8 4.2e-46
NP_001268229 (OMIM: 616813) arf-GAP with GTPase, A ( 580) 1429 185.9 4.5e-46
XP_016867223 (OMIM: 616813) PREDICTED: arf-GAP wit ( 580) 1429 185.9 4.5e-46
NP_055585 (OMIM: 605476) arf-GAP with GTPase, ANK ( 836) 1381 180.2 3.2e-44
XP_005268682 (OMIM: 605476) PREDICTED: arf-GAP wit (1172) 1381 180.4 4e-44
XP_005268683 (OMIM: 605476) PREDICTED: arf-GAP wit ( 856) 1304 171.0 2e-41
NP_001116244 (OMIM: 605476) arf-GAP with GTPase, A (1192) 1304 171.1 2.5e-41
XP_016874261 (OMIM: 605476) PREDICTED: arf-GAP wit (1192) 1304 171.1 2.5e-41
XP_016868958 (OMIM: 605953) PREDICTED: arf-GAP wit (1072) 433 66.3 8.3e-10
XP_016868957 (OMIM: 605953) PREDICTED: arf-GAP wit (1073) 433 66.3 8.3e-10
XP_006716629 (OMIM: 605953) PREDICTED: arf-GAP wit (1075) 433 66.3 8.3e-10
XP_006716628 (OMIM: 605953) PREDICTED: arf-GAP wit (1076) 433 66.3 8.3e-10
XP_016868956 (OMIM: 605953) PREDICTED: arf-GAP wit (1087) 433 66.3 8.4e-10
NP_001234925 (OMIM: 605953) arf-GAP with SH3 domai (1122) 433 66.3 8.6e-10
XP_006716627 (OMIM: 605953) PREDICTED: arf-GAP wit (1125) 433 66.3 8.6e-10
XP_011515355 (OMIM: 605953) PREDICTED: arf-GAP wit (1125) 433 66.3 8.6e-10
NP_060952 (OMIM: 605953) arf-GAP with SH3 domain, (1129) 433 66.3 8.6e-10
XP_006716626 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 433 66.3 8.6e-10
XP_011515354 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 433 66.3 8.6e-10
XP_005250982 (OMIM: 605953) PREDICTED: arf-GAP wit (1132) 433 66.3 8.6e-10
XP_011510907 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 410 63.4 4.5e-09
XP_011510906 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 410 63.4 4.5e-09
XP_011510908 (OMIM: 607766) PREDICTED: arf-GAP wit ( 776) 410 63.4 4.5e-09
NP_036419 (OMIM: 607766) arf-GAP with coiled-coil, ( 778) 410 63.4 4.5e-09
XP_006713620 (OMIM: 607766) PREDICTED: arf-GAP wit ( 785) 410 63.4 4.6e-09
XP_016861538 (OMIM: 607766) PREDICTED: arf-GAP wit ( 806) 410 63.4 4.6e-09
XP_016861537 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 410 63.4 4.7e-09
XP_011510905 (OMIM: 607766) PREDICTED: arf-GAP wit ( 813) 410 63.4 4.7e-09
XP_011510904 (OMIM: 607766) PREDICTED: arf-GAP wit ( 820) 410 63.4 4.7e-09
XP_016861536 (OMIM: 607766) PREDICTED: arf-GAP wit ( 841) 410 63.4 4.8e-09
>>NP_055729 (OMIM: 608651) arf-GAP with GTPase, ANK repe (804 aa)
initn: 5290 init1: 5290 opt: 5290 Z-score: 3457.8 bits: 650.7 E(85289): 7.4e-186
Smith-Waterman score: 5290; 99.8% identity (99.9% similar) in 804 aa overlap (1-804:1-804)
10 20 30 40 50 60
pF1KSD MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSISQKELRIDVPPT
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_055 GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SSPKTNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSPKTNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD STSNFKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 STSNFKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD CESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD LGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIR
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_055 LGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTAL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD HLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVL
730 740 750 760 770 780
790 800
pF1KSD MATPNLSRRNNNRNNSSGRVPTII
::::::::::::::::::::::::
NP_055 MATPNLSRRNNNRNNSSGRVPTII
790 800
>>XP_005246116 (OMIM: 608651) PREDICTED: arf-GAP with GT (808 aa)
initn: 4641 init1: 4641 opt: 5272 Z-score: 3446.0 bits: 648.5 E(85289): 3.3e-185
Smith-Waterman score: 5272; 99.3% identity (99.4% similar) in 808 aa overlap (1-804:1-808)
10 20 30 40 50 60
pF1KSD MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
10 20 30 40 50 60
70 80 90 100 110
pF1KSD QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPE----GGRFKKEIVVDGQ
::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_005 QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEDMDAGGRFKKEIVVDGQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD SYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD GTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD QLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSISQKELRID
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_005 QLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRID
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD VPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD SGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD CAPISSPKTNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CAPISSPKTNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKH
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD RRKKSTSNFKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRKKSTSNFKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD SLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSG
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD IHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKE
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_005 IHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKE
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD RWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDG
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD RTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE
730 740 750 760 770 780
780 790 800
pF1KSD RFVLMATPNLSRRNNNRNNSSGRVPTII
::::::::::::::::::::::::::::
XP_005 RFVLMATPNLSRRNNNRNNSSGRVPTII
790 800
>>XP_011508851 (OMIM: 608651) PREDICTED: arf-GAP with GT (1073 aa)
initn: 4641 init1: 4641 opt: 4932 Z-score: 3223.3 bits: 607.7 E(85289): 8.4e-173
Smith-Waterman score: 4932; 99.2% identity (99.3% similar) in 754 aa overlap (55-804:320-1073)
30 40 50 60 70 80
pF1KSD PNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGK
::::::::::::::::::::::::::::::
XP_011 SRPRGYFSLRRAPAEAHSSSAESIDGSPRRDAFVNSQEWTLSRSVPELKVGIVGNLASGK
290 300 310 320 330 340
90 100 110 120 130 140
pF1KSD SALVHRYLTGTYVQEESPE----GGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAV
::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_011 SALVHRYLTGTYVQEESPEDMDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAV
350 360 370 380 390 400
150 160 170 180 190 200
pF1KSD IFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSN
410 420 430 440 450 460
210 220 230 240 250 260
pF1KSD DLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQV
470 480 490 500 510 520
270 280 290 300 310 320
pF1KSD SAVHISQTSNGGGSLSDYSSSVPSTPSISQKELRIDVPPTANTPTPVRKQSKRRSNLFTS
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 SAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTS
530 540 550 560 570 580
330 340 350 360 370 380
pF1KSD RKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTY
590 600 610 620 630 640
390 400 410 420 430 440
pF1KSD HPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPN
650 660 670 680 690 700
450 460 470 480 490 500
pF1KSD SDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQEEN
710 720 730 740 750 760
510 520 530 540 550 560
pF1KSD FEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQ
770 780 790 800 810 820
570 580 590 600 610 620
pF1KSD SIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
XP_011 SIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVEL
830 840 850 860 870 880
630 640 650 660 670 680
pF1KSD IKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLG
890 900 910 920 930 940
690 700 710 720 730 740
pF1KSD QHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGV
950 960 970 980 990 1000
750 760 770 780 790 800
pF1KSD DVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSGRV
1010 1020 1030 1040 1050 1060
pF1KSD PTII
::::
XP_011 PTII
1070
>>XP_011508850 (OMIM: 608651) PREDICTED: arf-GAP with GT (1098 aa)
initn: 2589 init1: 2589 opt: 2896 Z-score: 1898.9 bits: 362.7 E(85289): 4.9e-99
Smith-Waterman score: 4872; 96.0% identity (96.1% similar) in 779 aa overlap (55-804:320-1098)
30 40 50 60 70 80
pF1KSD PNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGK
::::::::::::::::::::::::::::::
XP_011 SRPRGYFSLRRAPAEAHSSSAESIDGSPRRDAFVNSQEWTLSRSVPELKVGIVGNLASGK
290 300 310 320 330 340
90 100 110 120 130 140
pF1KSD SALVHRYLTGTYVQEESPE----GGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAV
::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_011 SALVHRYLTGTYVQEESPEDMDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAV
350 360 370 380 390 400
150 160 170 180 190 200
pF1KSD IFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSN
410 420 430 440 450 460
210 220 230 240 250 260
pF1KSD DLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQV
470 480 490 500 510 520
270 280 290 300 310 320
pF1KSD SAVHISQTSNGGGSLSDYSSSVPSTPSISQKELRIDVPPTANTPTPVRKQSKRRSNLFTS
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 SAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTS
530 540 550 560 570 580
330 340 350 360 370 380
pF1KSD RKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTY
590 600 610 620 630 640
390 400 410 420 430 440
pF1KSD HPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPN
650 660 670 680 690 700
450 460 470 480 490
pF1KSD SDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAE-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEAKRKA
710 720 730 740 750 760
500 510 520 530
pF1KSD --------------------EQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQIL
::::::::::::::::::::::::::::::::::::::::
XP_011 WKLNRVGSLRNIYSSSTNTEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQIL
770 780 790 800 810 820
540 550 560 570 580 590
pF1KSD ASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECS
830 840 850 860 870 880
600 610 620 630 640 650
pF1KSD GIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEK
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_011 GIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEK
890 900 910 920 930 940
660 670 680 690 700 710
pF1KSD ERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGD
950 960 970 980 990 1000
720 730 740 750 760 770
pF1KSD GRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPD
1010 1020 1030 1040 1050 1060
780 790 800
pF1KSD ERFVLMATPNLSRRNNNRNNSSGRVPTII
:::::::::::::::::::::::::::::
XP_011 ERFVLMATPNLSRRNNNRNNSSGRVPTII
1070 1080 1090
>>NP_001032208 (OMIM: 608651) arf-GAP with GTPase, ANK r (857 aa)
initn: 2901 init1: 2872 opt: 2877 Z-score: 1887.9 bits: 360.3 E(85289): 2e-98
Smith-Waterman score: 5036; 93.4% identity (93.5% similar) in 836 aa overlap (1-783:1-836)
10 20 30 40 50 60
pF1KSD MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSISQKELRIDVPPT
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_001 GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI
370 380 390 400 410 420
430 440
pF1KSD SSPKTNGLSKDMSSLHISPNS---------------------------------------
:::::::::::::::::::::
NP_001 SSPKTNGLSKDMSSLHISPNSGNVTSASGSQMASGISLVSFNSRPDGMHQRSYSVSSADQ
430 440 450 460 470 480
450 460 470 480
pF1KSD --------------DTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKA
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSEATVIANSAISSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKA
490 500 510 520 530 540
490 500 510 520 530 540
pF1KSD DGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNK
550 560 570 580 590 600
550 560 570 580 590 600
pF1KSD SRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSR
610 620 630 640 650 660
610 620 630 640 650 660
pF1KSD VRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKL
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKL
670 680 690 700 710 720
670 680 690 700 710 720
pF1KSD FLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKG
730 740 750 760 770 780
730 740 750 760 770 780
pF1KSD NVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLS
790 800 810 820 830 840
790 800
pF1KSD RRNNNRNNSSGRVPTII
NP_001 RRNNNRNNSSGRVPTII
850
>>XP_006712298 (OMIM: 608651) PREDICTED: arf-GAP with GT (882 aa)
initn: 4923 init1: 2872 opt: 2877 Z-score: 1887.8 bits: 360.3 E(85289): 2.1e-98
Smith-Waterman score: 4805; 90.4% identity (90.6% similar) in 836 aa overlap (1-758:1-836)
10 20 30 40 50 60
pF1KSD MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSISQKELRIDVPPT
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_006 GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI
370 380 390 400 410 420
430 440
pF1KSD SSPKTNGLSKDMSSLHISPNS---------------------------------------
:::::::::::::::::::::
XP_006 SSPKTNGLSKDMSSLHISPNSGNVTSASGSQMASGISLVSFNSRPDGMHQRSYSVSSADQ
430 440 450 460 470 480
450 460 470 480
pF1KSD --------------DTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKA
::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WSEATVIANSAISSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKA
490 500 510 520 530 540
490 500 510 520
pF1KSD DGLSGTAE-------------------------EQEENFEFIIVSLTGQTWHFEATTYEE
:::::::: :::::::::::::::::::::::::::
XP_006 DGLSGTAEAKRKAWKLNRVGSLRNIYSSSTNTEEQEENFEFIIVSLTGQTWHFEATTYEE
550 560 570 580 590 600
530 540 550 560 570 580
pF1KSD RDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWA
610 620 630 640 650 660
590 600 610 620 630 640
pF1KSD SLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQG
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
XP_006 SLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQG
670 680 690 700 710 720
650 660 670 680 690 700
pF1KSD RTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHG
730 740 750 760 770 780
710 720 730 740 750 760
pF1KSD SRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQ
790 800 810 820 830 840
770 780 790 800
pF1KSD ECIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSGRVPTII
XP_006 ECIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSGRVPTII
850 860 870 880
>--
initn: 309 init1: 309 opt: 309 Z-score: 217.4 bits: 51.3 E(85289): 2.3e-05
Smith-Waterman score: 309; 100.0% identity (100.0% similar) in 46 aa overlap (759-804:837-882)
730 740 750 760 770 780
pF1KSD VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSR
::::::::::::::::::::::::::::::
XP_006 VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSR
810 820 830 840 850 860
790 800
pF1KSD RNNNRNNSSGRVPTII
::::::::::::::::
XP_006 RNNNRNNSSGRVPTII
870 880
>>XP_006712297 (OMIM: 608651) PREDICTED: arf-GAP with GT (886 aa)
initn: 4274 init1: 2223 opt: 2859 Z-score: 1876.0 bits: 358.1 E(85289): 9.3e-98
Smith-Waterman score: 4787; 90.0% identity (90.1% similar) in 840 aa overlap (1-758:1-840)
10 20 30 40 50 60
pF1KSD MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
10 20 30 40 50 60
70 80 90 100 110
pF1KSD QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPE----GGRFKKEIVVDGQ
::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_006 QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEDMDAGGRFKKEIVVDGQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD SYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD GTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD QLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSISQKELRID
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_006 QLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRID
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD VPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD SGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSA
370 380 390 400 410 420
420 430 440
pF1KSD CAPISSPKTNGLSKDMSSLHISPNS-----------------------------------
:::::::::::::::::::::::::
XP_006 CAPISSPKTNGLSKDMSSLHISPNSGNVTSASGSQMASGISLVSFNSRPDGMHQRSYSVS
430 440 450 460 470 480
450 460 470 480
pF1KSD ------------------DTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTS
::::::::::::::::::::::::::::::::::::::::::
XP_006 SADQWSEATVIANSAISSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTS
490 500 510 520 530 540
490 500 510
pF1KSD NFKADGLSGTAE-------------------------EQEENFEFIIVSLTGQTWHFEAT
:::::::::::: :::::::::::::::::::::::
XP_006 NFKADGLSGTAEAKRKAWKLNRVGSLRNIYSSSTNTEEQEENFEFIIVSLTGQTWHFEAT
550 560 570 580 590 600
520 530 540 550 560 570
pF1KSD TYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQN
610 620 630 640 650 660
580 590 600 610 620 630
pF1KSD PNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEE
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
XP_006 PNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEE
670 680 690 700 710 720
640 650 660 670 680 690
pF1KSD SSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILL
730 740 750 760 770 780
700 710 720 730 740 750
pF1KSD LAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQ
790 800 810 820 830 840
760 770 780 790 800
pF1KSD ASSQECIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSGRVPTII
XP_006 ASSQECIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSGRVPTII
850 860 870 880
>--
initn: 309 init1: 309 opt: 309 Z-score: 217.4 bits: 51.3 E(85289): 2.3e-05
Smith-Waterman score: 309; 100.0% identity (100.0% similar) in 46 aa overlap (759-804:841-886)
730 740 750 760 770 780
pF1KSD VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSR
::::::::::::::::::::::::::::::
XP_006 VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSR
820 830 840 850 860 870
790 800
pF1KSD RNNNRNNSSGRVPTII
::::::::::::::::
XP_006 RNNNRNNSSGRVPTII
880
>>XP_006712300 (OMIM: 608651) PREDICTED: arf-GAP with GT (1147 aa)
initn: 4583 init1: 2532 opt: 2537 Z-score: 1665.2 bits: 319.5 E(85289): 5.2e-86
Smith-Waterman score: 4465; 89.8% identity (89.9% similar) in 782 aa overlap (55-758:320-1101)
30 40 50 60 70 80
pF1KSD PNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGK
::::::::::::::::::::::::::::::
XP_006 SRPRGYFSLRRAPAEAHSSSAESIDGSPRRDAFVNSQEWTLSRSVPELKVGIVGNLASGK
290 300 310 320 330 340
90 100 110 120 130 140
pF1KSD SALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVF
350 360 370 380 390 400
150 160 170 180 190 200
pF1KSD SLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKR
410 420 430 440 450 460
210 220 230 240 250 260
pF1KSD CTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVH
470 480 490 500 510 520
270 280 290 300 310 320
pF1KSD ISQTSNGGGSLSDYSSSVPSTPSISQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGS
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
XP_006 ISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGS
530 540 550 560 570 580
330 340 350 360 370 380
pF1KSD DPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSL
590 600 610 620 630 640
390 400 410 420 430 440
pF1KSD HDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNS---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGNV
650 660 670 680 690 700
450
pF1KSD --------------------------------------------------DTGLGDSVCS
::::::::::
XP_006 TSASGSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSAISSDTGLGDSVCS
710 720 730 740 750 760
460 470 480 490
pF1KSD SPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAE----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEAKRKAWKLNRVGSLRN
770 780 790 800 810 820
500 510 520 530 540
pF1KSD ---------EQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKN
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IYSSSTNTEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKN
830 840 850 860 870 880
550 560 570 580 590 600
pF1KSD KSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLS
890 900 910 920 930 940
610 620 630 640 650 660
pF1KSD RVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQK
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQK
950 960 970 980 990 1000
670 680 690 700 710 720
pF1KSD LFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRK
1010 1020 1030 1040 1050 1060
730 740 750 760 770 780
pF1KSD GNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNL
::::::::::::::::::::::::::::::::
XP_006 GNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNL
1070 1080 1090 1100 1110 1120
790 800
pF1KSD SRRNNNRNNSSGRVPTII
XP_006 SRRNNNRNNSSGRVPTII
1130 1140
>--
initn: 309 init1: 309 opt: 309 Z-score: 216.0 bits: 51.4 E(85289): 2.7e-05
Smith-Waterman score: 309; 100.0% identity (100.0% similar) in 46 aa overlap (759-804:1102-1147)
730 740 750 760 770 780
pF1KSD VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSR
::::::::::::::::::::::::::::::
XP_006 VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSR
1080 1090 1100 1110 1120 1130
790 800
pF1KSD RNNNRNNSSGRVPTII
::::::::::::::::
XP_006 RNNNRNNSSGRVPTII
1140
>>XP_006712302 (OMIM: 608651) PREDICTED: arf-GAP with GT (1151 aa)
initn: 4274 init1: 2223 opt: 2519 Z-score: 1653.5 bits: 317.3 E(85289): 2.3e-85
Smith-Waterman score: 4447; 89.3% identity (89.4% similar) in 786 aa overlap (55-758:320-1105)
30 40 50 60 70 80
pF1KSD PNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGK
::::::::::::::::::::::::::::::
XP_006 SRPRGYFSLRRAPAEAHSSSAESIDGSPRRDAFVNSQEWTLSRSVPELKVGIVGNLASGK
290 300 310 320 330 340
90 100 110 120 130 140
pF1KSD SALVHRYLTGTYVQEESPE----GGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAV
::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_006 SALVHRYLTGTYVQEESPEDMDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAV
350 360 370 380 390 400
150 160 170 180 190 200
pF1KSD IFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSN
410 420 430 440 450 460
210 220 230 240 250 260
pF1KSD DLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQV
470 480 490 500 510 520
270 280 290 300 310 320
pF1KSD SAVHISQTSNGGGSLSDYSSSVPSTPSISQKELRIDVPPTANTPTPVRKQSKRRSNLFTS
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_006 SAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTS
530 540 550 560 570 580
330 340 350 360 370 380
pF1KSD RKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTY
590 600 610 620 630 640
390 400 410 420 430 440
pF1KSD HPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPN
650 660 670 680 690 700
pF1KSD S-----------------------------------------------------DTGLGD
: ::::::
XP_006 SGNVTSASGSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSAISSDTGLGD
710 720 730 740 750 760
450 460 470 480 490
pF1KSD SVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAE------------
::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEAKRKAWKLNRVG
770 780 790 800 810 820
500 510 520 530 540
pF1KSD -------------EQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCE
:::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLRNIYSSSTNTEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCE
830 840 850 860 870 880
550 560 570 580 590 600
pF1KSD SSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLG
890 900 910 920 930 940
610 620 630 640 650 660
pF1KSD THLSRVRSLDLDDWPIELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAK
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
XP_006 THLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAK
950 960 970 980 990 1000
670 680 690 700 710 720
pF1KSD YEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHL
1010 1020 1030 1040 1050 1060
730 740 750 760 770 780
pF1KSD ACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMA
::::::::::::::::::::::::::::::::::::
XP_006 ACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMA
1070 1080 1090 1100 1110 1120
790 800
pF1KSD TPNLSRRNNNRNNSSGRVPTII
XP_006 TPNLSRRNNNRNNSSGRVPTII
1130 1140 1150
>--
initn: 309 init1: 309 opt: 309 Z-score: 216.0 bits: 51.4 E(85289): 2.7e-05
Smith-Waterman score: 309; 100.0% identity (100.0% similar) in 46 aa overlap (759-804:1106-1151)
730 740 750 760 770 780
pF1KSD VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSR
::::::::::::::::::::::::::::::
XP_006 VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSR
1080 1090 1100 1110 1120 1130
790 800
pF1KSD RNNNRNNSSGRVPTII
::::::::::::::::
XP_006 RNNNRNNSSGRVPTII
1140 1150
>>XP_011508849 (OMIM: 608651) PREDICTED: arf-GAP with GT (1126 aa)
initn: 2723 init1: 2424 opt: 2424 Z-score: 1591.8 bits: 305.9 E(85289): 6.3e-82
Smith-Waterman score: 4816; 92.7% identity (92.8% similar) in 807 aa overlap (55-804:320-1126)
30 40 50 60 70 80
pF1KSD PNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGK
::::::::::::::::::::::::::::::
XP_011 SRPRGYFSLRRAPAEAHSSSAESIDGSPRRDAFVNSQEWTLSRSVPELKVGIVGNLASGK
290 300 310 320 330 340
90 100 110 120 130 140
pF1KSD SALVHRYLTGTYVQEESPE----GGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAV
::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_011 SALVHRYLTGTYVQEESPEDMDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAV
350 360 370 380 390 400
150 160 170 180 190 200
pF1KSD IFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSN
410 420 430 440 450 460
210 220 230 240 250 260
pF1KSD DLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQV
470 480 490 500 510 520
270 280 290 300 310 320
pF1KSD SAVHISQTSNGGGSLSDYSSSVPSTPSISQKELRIDVPPTANTPTPVRKQSKRRSNLFTS
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 SAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTS
530 540 550 560 570 580
330 340 350 360 370 380
pF1KSD RKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTY
590 600 610 620 630 640
390 400 410 420 430 440
pF1KSD HPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPN
650 660 670 680 690 700
pF1KSD S-----------------------------------------------------DTGLGD
: ::::::
XP_011 SGNVTSASGSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSAISSDTGLGD
710 720 730 740 750 760
450 460 470 480 490 500
pF1KSD SVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQEENFEFIIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQEENFEFIIVS
770 780 790 800 810 820
510 520 530 540 550 560
pF1KSD LTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRG
830 840 850 860 870 880
570 580 590 600 610 620
pF1KSD NSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSI
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_011 NSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSI
890 900 910 920 930 940
630 640 650 660 670 680
pF1KSD GNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRAT
950 960 970 980 990 1000
690 700 710 720 730 740
pF1KSD ADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDA
1010 1020 1030 1040 1050 1060
750 760 770 780 790 800
pF1KSD HGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSGRVPTII
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSGRVPTII
1070 1080 1090 1100 1110 1120
804 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:02:02 2016 done: Thu Nov 3 05:02:04 2016
Total Scan time: 14.070 Total Display time: 0.300
Function used was FASTA [36.3.4 Apr, 2011]