FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1125, 1186 aa 1>>>pF1KSDA1125 1186 - 1186 aa - 1186 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.5593+/-0.00116; mu= -5.6798+/- 0.070 mean_var=349.5093+/-70.195, 0's: 0 Z-trim(112.5): 68 B-trim: 0 in 0/52 Lambda= 0.068603 statistics sampled from 13172 (13220) to 13172 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.406), width: 16 Scan time: 5.960 The best scores are: opt bits E(32554) CCDS63300.1 ZMYND8 gene_id:23613|Hs108|chr20 (1214) 7609 768.1 0 CCDS63306.1 ZMYND8 gene_id:23613|Hs108|chr20 (1234) 7609 768.1 0 CCDS74738.1 ZMYND8 gene_id:23613|Hs108|chr20 (1186) 7358 743.3 8.2e-214 CCDS13404.1 ZMYND8 gene_id:23613|Hs108|chr20 (1160) 5583 567.6 6.2e-161 CCDS63301.1 ZMYND8 gene_id:23613|Hs108|chr20 (1168) 5583 567.6 6.2e-161 CCDS13405.1 ZMYND8 gene_id:23613|Hs108|chr20 (1188) 5583 567.6 6.3e-161 CCDS46613.1 ZMYND8 gene_id:23613|Hs108|chr20 (1135) 5042 514.0 8e-145 CCDS63305.1 ZMYND8 gene_id:23613|Hs108|chr20 (1136) 5016 511.5 4.8e-144 CCDS63304.1 ZMYND8 gene_id:23613|Hs108|chr20 (1054) 4573 467.6 7.1e-131 CCDS63303.1 ZMYND8 gene_id:23613|Hs108|chr20 (1134) 4307 441.3 6.3e-123 >>CCDS63300.1 ZMYND8 gene_id:23613|Hs108|chr20 (1214 aa) initn: 7877 init1: 7600 opt: 7609 Z-score: 4086.2 bits: 768.1 E(32554): 0 Smith-Waterman score: 7823; 97.7% identity (97.7% similar) in 1214 aa overlap (1-1186:1-1214) 10 20 30 40 50 60 pF1KSD MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 QHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 GQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD NYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 NYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 GRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD TGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 GAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGED 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD HSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 HSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD TSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKMQRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKMQRQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPSTSTITLVTSTQSSPLVTSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 QQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPSTSTITLVTSTQSSPLVTSSG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEI 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD RRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 RRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVD 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD ETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 ETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQG 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KSD S----------------DH------------SRSNKSSWSSSDEKRGSTRSDHNTSTSTK : :: ::::::::::::::::::::::::::::: CCDS63 SVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1150 1160 1170 1180 1190 1200 1180 pF1KSD SLLPKESRLDTFWD :::::::::::::: CCDS63 SLLPKESRLDTFWD 1210 >>CCDS63306.1 ZMYND8 gene_id:23613|Hs108|chr20 (1234 aa) initn: 7877 init1: 7600 opt: 7609 Z-score: 4086.1 bits: 768.1 E(32554): 0 Smith-Waterman score: 7823; 97.7% identity (97.7% similar) in 1214 aa overlap (1-1186:21-1234) 10 20 30 40 pF1KSD MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS :::::::::::::::::::::::::::::::::::::::: CCDS63 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 70 80 90 100 110 120 110 120 130 140 150 160 pF1KSD LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 130 140 150 160 170 180 170 180 190 200 210 220 pF1KSD AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 190 200 210 220 230 240 230 240 250 260 270 280 pF1KSD LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KSD VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KSD SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 430 440 450 460 470 480 470 480 490 500 510 520 pF1KSD ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 490 500 510 520 530 540 530 540 550 560 570 580 pF1KSD DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 610 620 630 640 650 660 650 660 670 680 690 700 pF1KSD PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 670 680 690 700 710 720 710 720 730 740 750 760 pF1KSD VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 730 740 750 760 770 780 770 780 790 800 810 820 pF1KSD PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 790 800 810 820 830 840 830 840 850 860 870 880 pF1KSD SSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPS 850 860 870 880 890 900 890 900 910 920 930 940 pF1KSD TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KSD MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KSD DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KSD SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST 1090 1100 1110 1120 1130 1140 1130 1140 1150 pF1KSD LDLSGSRETPSSILLGSNQGS----------------DH------------SRSNKSSWS ::::::::::::::::::::: :: ::::::::: CCDS63 LDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWS 1150 1160 1170 1180 1190 1200 1160 1170 1180 pF1KSD SSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD :::::::::::::::::::::::::::::::::: CCDS63 SSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1210 1220 1230 >>CCDS74738.1 ZMYND8 gene_id:23613|Hs108|chr20 (1186 aa) initn: 7339 init1: 7339 opt: 7358 Z-score: 3952.1 bits: 743.3 E(32554): 8.2e-214 Smith-Waterman score: 7661; 97.9% identity (97.9% similar) in 1186 aa overlap (1-1186:26-1186) 10 20 30 pF1KSD MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQ ::::::::::::::::::::::::::::::::::: CCDS74 MFSSLQKSFNLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQ 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD DTSTSPIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCH ::::::::::::::::::::::: :::::::::::: CCDS74 DTSTSPIKKKKKPGLLNSNNKEQ-------------------------DGRNDFYCWVCH 70 80 90 100 110 120 130 140 150 pF1KSD REGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 REGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLS 100 110 120 130 140 150 160 170 180 190 200 210 pF1KSD YLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 YLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLA 160 170 180 190 200 210 220 230 240 250 260 270 pF1KSD DAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCS 220 230 240 250 260 270 280 290 300 310 320 330 pF1KSD NPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 NPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKT 280 290 300 310 320 330 340 350 360 370 380 390 pF1KSD KSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQE 340 350 360 370 380 390 400 410 420 430 440 450 pF1KSD KVKLNFDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KVKLNFDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKAT 400 410 420 430 440 450 460 470 480 490 500 510 pF1KSD SSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSI 460 470 480 490 500 510 520 530 540 550 560 570 pF1KSD LNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINE 520 530 540 550 560 570 580 590 600 610 620 630 pF1KSD ISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKK 580 590 600 610 620 630 640 650 660 670 680 690 pF1KSD PKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDE 640 650 660 670 680 690 700 710 720 730 740 750 pF1KSD TDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 TDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSH 700 710 720 730 740 750 760 770 780 790 800 810 pF1KSD SPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ 760 770 780 790 800 810 820 830 840 850 860 870 pF1KSD RVVWNSSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 RVVWNSSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEI 820 830 840 850 860 870 880 890 900 910 920 930 pF1KSD TQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 TQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMD 880 890 900 910 920 930 940 950 960 970 980 990 pF1KSD AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQS 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 pF1KSD LEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHW 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 pF1KSD PEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSK 1060 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 pF1KSD ESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLL 1120 1130 1140 1150 1160 1170 1180 pF1KSD PKESRLDTFWD ::::::::::: CCDS74 PKESRLDTFWD 1180 >>CCDS13404.1 ZMYND8 gene_id:23613|Hs108|chr20 (1160 aa) initn: 7567 init1: 5557 opt: 5583 Z-score: 3002.8 bits: 567.6 E(32554): 6.2e-161 Smith-Waterman score: 7479; 96.0% identity (96.1% similar) in 1186 aa overlap (1-1186:21-1160) 10 20 30 40 pF1KSD MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS :::::::::::::::::::::::::::::::::::::::: CCDS13 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 70 80 90 100 110 120 110 120 130 140 150 160 pF1KSD LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 130 140 150 160 170 180 170 180 190 200 210 220 pF1KSD AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 190 200 210 220 230 240 230 240 250 260 270 280 pF1KSD LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KSD VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KSD SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 430 440 450 460 470 480 470 480 490 500 510 520 pF1KSD ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 490 500 510 520 530 540 530 540 550 560 570 580 pF1KSD DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 610 620 630 640 650 660 650 660 670 680 690 700 pF1KSD PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 670 680 690 700 710 720 710 720 730 740 750 760 pF1KSD VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 730 740 750 760 770 780 770 780 790 800 810 820 pF1KSD PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 790 800 810 820 830 840 830 840 850 860 870 880 pF1KSD SSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPS ::. ::::::::::: CCDS13 SST----------------------------------------------VQQKEITQSPS 850 890 900 910 920 930 940 pF1KSD TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT 860 870 880 890 900 910 950 960 970 980 990 1000 pF1KSD MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER 920 930 940 950 960 970 1010 1020 1030 1040 1050 1060 pF1KSD DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK 980 990 1000 1010 1020 1030 1070 1080 1090 1100 1110 1120 pF1KSD SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST 1040 1050 1060 1070 1080 1090 1130 1140 1150 1160 1170 1180 pF1KSD LDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESR 1100 1110 1120 1130 1140 1150 pF1KSD LDTFWD :::::: CCDS13 LDTFWD 1160 >>CCDS63301.1 ZMYND8 gene_id:23613|Hs108|chr20 (1168 aa) initn: 7545 init1: 5557 opt: 5583 Z-score: 3002.7 bits: 567.6 E(32554): 6.2e-161 Smith-Waterman score: 7403; 93.8% identity (93.9% similar) in 1214 aa overlap (1-1186:1-1168) 10 20 30 40 50 60 pF1KSD MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQSE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 QHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 GQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVF 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD NYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 NYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 GRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD TGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD EYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADP 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD GAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 GAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGED 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD HSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 HSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD TSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKMQRQ ::::::::::::::::::::::::::::::::::::::::::. CCDS63 TSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSST----------------- 790 800 810 820 850 860 870 880 890 900 pF1KSD QQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPSTSTITLVTSTQSSPLVTSSG ::::::::::::::::::::::::::::::: CCDS63 -----------------------------VQQKEITQSPSTSTITLVTSTQSSPLVTSSG 830 840 850 910 920 930 940 950 960 pF1KSD SMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEI 860 870 880 890 900 910 970 980 990 1000 1010 1020 pF1KSD RRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 RRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVD 920 930 940 950 960 970 1030 1040 1050 1060 1070 1080 pF1KSD ETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 ETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTE 980 990 1000 1010 1020 1030 1090 1100 1110 1120 1130 1140 pF1KSD TLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQG 1040 1050 1060 1070 1080 1090 1150 1160 1170 pF1KSD S----------------DH------------SRSNKSSWSSSDEKRGSTRSDHNTSTSTK : :: ::::::::::::::::::::::::::::: CCDS63 SVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1100 1110 1120 1130 1140 1150 1180 pF1KSD SLLPKESRLDTFWD :::::::::::::: CCDS63 SLLPKESRLDTFWD 1160 >>CCDS13405.1 ZMYND8 gene_id:23613|Hs108|chr20 (1188 aa) initn: 7545 init1: 5557 opt: 5583 Z-score: 3002.6 bits: 567.6 E(32554): 6.3e-161 Smith-Waterman score: 7403; 93.8% identity (93.9% similar) in 1214 aa overlap (1-1186:21-1188) 10 20 30 40 pF1KSD MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS :::::::::::::::::::::::::::::::::::::::: CCDS13 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 70 80 90 100 110 120 110 120 130 140 150 160 pF1KSD LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 130 140 150 160 170 180 170 180 190 200 210 220 pF1KSD AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 190 200 210 220 230 240 230 240 250 260 270 280 pF1KSD LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 250 260 270 280 290 300 290 300 310 320 330 340 pF1KSD VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KSD SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 370 380 390 400 410 420 410 420 430 440 450 460 pF1KSD FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 430 440 450 460 470 480 470 480 490 500 510 520 pF1KSD ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 490 500 510 520 530 540 530 540 550 560 570 580 pF1KSD DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 610 620 630 640 650 660 650 660 670 680 690 700 pF1KSD PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 670 680 690 700 710 720 710 720 730 740 750 760 pF1KSD VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 730 740 750 760 770 780 770 780 790 800 810 820 pF1KSD PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 790 800 810 820 830 840 830 840 850 860 870 880 pF1KSD SSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPS ::. ::::::::::: CCDS13 SST----------------------------------------------VQQKEITQSPS 850 890 900 910 920 930 940 pF1KSD TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT 860 870 880 890 900 910 950 960 970 980 990 1000 pF1KSD MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER 920 930 940 950 960 970 1010 1020 1030 1040 1050 1060 pF1KSD DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK 980 990 1000 1010 1020 1030 1070 1080 1090 1100 1110 1120 pF1KSD SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST 1040 1050 1060 1070 1080 1090 1130 1140 1150 pF1KSD LDLSGSRETPSSILLGSNQGS----------------DH------------SRSNKSSWS ::::::::::::::::::::: :: ::::::::: CCDS13 LDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWS 1100 1110 1120 1130 1140 1150 1160 1170 1180 pF1KSD SSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD :::::::::::::::::::::::::::::::::: CCDS13 SSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1160 1170 1180 >>CCDS46613.1 ZMYND8 gene_id:23613|Hs108|chr20 (1135 aa) initn: 7007 init1: 4997 opt: 5042 Z-score: 2713.5 bits: 514.0 E(32554): 8e-145 Smith-Waterman score: 7241; 93.9% identity (94.0% similar) in 1186 aa overlap (1-1186:21-1135) 10 20 30 40 pF1KSD MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS :::::::::::::::::::::::::::::::::::::::: CCDS46 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV :::::::::::::::::: ::::::::::::::::: CCDS46 PIKKKKKPGLLNSNNKEQ-------------------------DGRNDFYCWVCHREGQV 70 80 90 110 120 130 140 150 160 pF1KSD LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 100 110 120 130 140 150 170 180 190 200 210 220 pF1KSD AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 160 170 180 190 200 210 230 240 250 260 270 280 pF1KSD LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 220 230 240 250 260 270 290 300 310 320 330 340 pF1KSD VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 280 290 300 310 320 330 350 360 370 380 390 400 pF1KSD SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 340 350 360 370 380 390 410 420 430 440 450 460 pF1KSD FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 400 410 420 430 440 450 470 480 490 500 510 520 pF1KSD ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 460 470 480 490 500 510 530 540 550 560 570 580 pF1KSD DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 520 530 540 550 560 570 590 600 610 620 630 640 pF1KSD YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 580 590 600 610 620 630 650 660 670 680 690 700 pF1KSD PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 640 650 660 670 680 690 710 720 730 740 750 760 pF1KSD VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 700 710 720 730 740 750 770 780 790 800 810 820 pF1KSD PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 760 770 780 790 800 810 830 840 850 860 870 880 pF1KSD SSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPS ::. ::::::::::: CCDS46 SST----------------------------------------------VQQKEITQSPS 820 890 900 910 920 930 940 pF1KSD TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT 830 840 850 860 870 880 950 960 970 980 990 1000 pF1KSD MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER 890 900 910 920 930 940 1010 1020 1030 1040 1050 1060 pF1KSD DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK 950 960 970 980 990 1000 1070 1080 1090 1100 1110 1120 pF1KSD SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST 1010 1020 1030 1040 1050 1060 1130 1140 1150 1160 1170 1180 pF1KSD LDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESR 1070 1080 1090 1100 1110 1120 pF1KSD LDTFWD :::::: CCDS46 LDTFWD 1130 >>CCDS63305.1 ZMYND8 gene_id:23613|Hs108|chr20 (1136 aa) initn: 6506 init1: 4997 opt: 5016 Z-score: 2699.6 bits: 511.5 E(32554): 4.8e-144 Smith-Waterman score: 6937; 89.5% identity (89.6% similar) in 1214 aa overlap (1-1186:21-1136) 10 20 30 40 pF1KSD MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS :::::::::::::::::::::::::::::::::::::::: CCDS63 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV :::::::::::::::::: ::::::::::::::::: CCDS63 PIKKKKKPGLLNSNNKEQ-------------------------DGRNDFYCWVCHREGQV 70 80 90 110 120 130 140 150 160 pF1KSD LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 100 110 120 130 140 150 170 180 190 200 210 220 pF1KSD AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 160 170 180 190 200 210 230 240 250 260 270 280 pF1KSD LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 220 230 240 250 260 270 290 300 310 320 330 340 pF1KSD VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 280 290 300 310 320 330 350 360 370 380 390 400 pF1KSD SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 340 350 360 370 380 390 410 420 430 440 450 460 pF1KSD FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 400 410 420 430 440 450 470 480 490 500 510 520 pF1KSD ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 460 470 480 490 500 510 530 540 550 560 570 580 pF1KSD DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 520 530 540 550 560 570 590 600 610 620 630 640 pF1KSD YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 580 590 600 610 620 630 650 660 670 680 690 700 pF1KSD PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 640 650 660 670 680 690 710 720 730 740 750 760 pF1KSD VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 700 710 720 730 740 750 770 780 790 800 810 820 pF1KSD PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 760 770 780 790 800 810 830 840 850 860 870 880 pF1KSD SSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPS ::. ::::::::::: CCDS63 SST----------------------------------------------VQQKEITQSPS 820 890 900 910 920 930 940 pF1KSD TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSK-------- 830 840 850 860 870 880 950 960 970 980 990 1000 pF1KSD MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER ::::::::::::::::::::::::::::::::::::::::: CCDS63 -------------------IRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER 890 900 910 920 1010 1020 1030 1040 1050 1060 pF1KSD DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK 930 940 950 960 970 980 1070 1080 1090 1100 1110 1120 pF1KSD SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST 990 1000 1010 1020 1030 1040 1130 1140 1150 pF1KSD LDLSGSRETPSSILLGSNQGS----------------DH------------SRSNKSSWS ::::::::::::::::::::: :: ::::::::: CCDS63 LDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYPAQKYHSRSNKSSWS 1050 1060 1070 1080 1090 1100 1160 1170 1180 pF1KSD SSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD :::::::::::::::::::::::::::::::::: CCDS63 SSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1110 1120 1130 >>CCDS63304.1 ZMYND8 gene_id:23613|Hs108|chr20 (1054 aa) initn: 4505 init1: 4505 opt: 4573 Z-score: 2463.1 bits: 467.6 E(32554): 7.1e-131 Smith-Waterman score: 6575; 87.2% identity (87.2% similar) in 1186 aa overlap (1-1186:21-1054) 10 20 30 40 pF1KSD MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS :::::::::::::::::::::::::::::::::::::::: CCDS63 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV :::::::::::::::::: ::::::::::::::::: CCDS63 PIKKKKKPGLLNSNNKEQ-------------------------DGRNDFYCWVCHREGQV 70 80 90 110 120 130 140 150 160 pF1KSD LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 100 110 120 130 140 150 170 180 190 200 210 220 pF1KSD AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 160 170 180 190 200 210 230 240 250 260 270 280 pF1KSD LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 220 230 240 250 260 270 290 300 310 320 330 340 pF1KSD VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 280 290 300 310 320 330 350 360 370 380 390 400 pF1KSD SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 340 350 360 370 380 390 410 420 430 440 450 460 pF1KSD FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 400 410 420 430 440 450 470 480 490 500 510 520 pF1KSD ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 460 470 480 490 500 510 530 540 550 560 570 580 pF1KSD DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 520 530 540 550 560 570 590 600 610 620 630 640 pF1KSD YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 580 590 600 610 620 630 650 660 670 680 690 700 pF1KSD PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 640 650 660 670 680 690 710 720 730 740 750 760 pF1KSD VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET ::::::::::::::::::::::::::::::::::::::::: CCDS63 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQD------------------- 700 710 720 730 770 780 790 800 810 820 pF1KSD PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN CCDS63 ------------------------------------------------------------ 830 840 850 860 870 880 pF1KSD SSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPS :::::::::::: CCDS63 ------------------------------------------------AVQQKEITQSPS 740 890 900 910 920 930 940 pF1KSD TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT 750 760 770 780 790 800 950 960 970 980 990 1000 pF1KSD MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER 810 820 830 840 850 860 1010 1020 1030 1040 1050 1060 pF1KSD DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK 870 880 890 900 910 920 1070 1080 1090 1100 1110 1120 pF1KSD SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST 930 940 950 960 970 980 1130 1140 1150 1160 1170 1180 pF1KSD LDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESR 990 1000 1010 1020 1030 1040 pF1KSD LDTFWD :::::: CCDS63 LDTFWD 1050 >>CCDS63303.1 ZMYND8 gene_id:23613|Hs108|chr20 (1134 aa) initn: 4679 init1: 4304 opt: 4307 Z-score: 2320.4 bits: 441.3 E(32554): 6.3e-123 Smith-Waterman score: 7267; 93.9% identity (93.9% similar) in 1186 aa overlap (1-1186:21-1134) 10 20 30 40 pF1KSD MDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS :::::::::::::::::::::::::::::::::::::::: CCDS63 MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV :::::::::::::::::: ::::::::::::::::: CCDS63 PIKKKKKPGLLNSNNKEQ-------------------------DGRNDFYCWVCHREGQV 70 80 90 110 120 130 140 150 160 pF1KSD LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 100 110 120 130 140 150 170 180 190 200 210 220 pF1KSD AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 160 170 180 190 200 210 230 240 250 260 270 280 pF1KSD LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 220 230 240 250 260 270 290 300 310 320 330 340 pF1KSD VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 280 290 300 310 320 330 350 360 370 380 390 400 pF1KSD SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 340 350 360 370 380 390 410 420 430 440 450 460 pF1KSD FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 400 410 420 430 440 450 470 480 490 500 510 520 pF1KSD ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL ::::::::::::: CCDS63 ASEESMDFLDKST----------------------------------------------- 460 530 540 550 560 570 580 pF1KSD DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 470 480 490 500 510 520 590 600 610 620 630 640 pF1KSD YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 530 540 550 560 570 580 650 660 670 680 690 700 pF1KSD PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 590 600 610 620 630 640 710 720 730 740 750 760 pF1KSD VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 650 660 670 680 690 700 770 780 790 800 810 820 pF1KSD PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 710 720 730 740 750 760 830 840 850 860 870 880 pF1KSD SSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPS 770 780 790 800 810 820 890 900 910 920 930 940 pF1KSD TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGT 830 840 850 860 870 880 950 960 970 980 990 1000 pF1KSD MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQER 890 900 910 920 930 940 1010 1020 1030 1040 1050 1060 pF1KSD DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 DRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMK 950 960 970 980 990 1000 1070 1080 1090 1100 1110 1120 pF1KSD SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGST 1010 1020 1030 1040 1050 1060 1130 1140 1150 1160 1170 1180 pF1KSD LDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESR 1070 1080 1090 1100 1110 1120 pF1KSD LDTFWD :::::: CCDS63 LDTFWD 1130 1186 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:03:44 2016 done: Thu Nov 3 05:03:45 2016 Total Scan time: 5.960 Total Display time: 0.690 Function used was FASTA [36.3.4 Apr, 2011]