Result of FASTA (ccds) for
pF1KSDA1135
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1135, 756 aa
1>>>pF1KSDA1135 756 - 756 aa - 756 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2501+/-0.000768; mu= 13.2673+/- 0.047
mean_var=143.0651+/-28.471, 0's: 0 Z-trim(113.0): 9 B-trim: 7 in 1/53
Lambda= 0.107228
statistics sampled from 13706 (13713) to 13706 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.421), width: 16
Scan time: 4.780
The best scores are: opt bits E(32554)
CCDS45829.1 SPIRE1 gene_id:56907|Hs108|chr18 ( 756) 5039 791.2 0
CCDS32790.2 SPIRE1 gene_id:56907|Hs108|chr18 ( 742) 2688 427.5 3.6e-119
CCDS45830.1 SPIRE1 gene_id:56907|Hs108|chr18 ( 622) 2315 369.8 7.4e-102
CCDS32516.1 SPIRE2 gene_id:84501|Hs108|chr16 ( 714) 1555 252.3 2e-66
>>CCDS45829.1 SPIRE1 gene_id:56907|Hs108|chr18 (756 aa)
initn: 5039 init1: 5039 opt: 5039 Z-score: 4218.3 bits: 791.2 E(32554): 0
Smith-Waterman score: 5039; 100.0% identity (100.0% similar) in 756 aa overlap (1-756:1-756)
10 20 30 40 50 60
pF1KSD MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
670 680 690 700 710 720
730 740 750
pF1KSD VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
::::::::::::::::::::::::::::::::::::
CCDS45 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
730 740 750
>>CCDS32790.2 SPIRE1 gene_id:56907|Hs108|chr18 (742 aa)
initn: 4935 init1: 2647 opt: 2688 Z-score: 2252.9 bits: 427.5 E(32554): 3.6e-119
Smith-Waterman score: 4911; 98.1% identity (98.1% similar) in 756 aa overlap (1-756:1-742)
10 20 30 40 50 60
pF1KSD MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
:::::::::::::::::::::::::::::::::::: ::::::::::
CCDS32 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL--------------DVTTPESTKN
370 380 390 400
430 440 450 460 470 480
pF1KSD LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
650 660 670 680 690 700
730 740 750
pF1KSD VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
::::::::::::::::::::::::::::::::::::
CCDS32 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
710 720 730 740
>>CCDS45830.1 SPIRE1 gene_id:56907|Hs108|chr18 (622 aa)
initn: 4100 init1: 2302 opt: 2315 Z-score: 1942.1 bits: 369.8 E(32554): 7.4e-102
Smith-Waterman score: 4076; 97.8% identity (97.8% similar) in 636 aa overlap (121-756:1-622)
100 110 120 130 140 150
pF1KSD WRDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIESLGIIIYKALDYGLKENEERELS
::::::::::::::::::::::::::::::
CCDS45 METEVIESLGIIIYKALDYGLKENEERELS
10 20 30
160 170 180 190 200 210
pF1KSD PPLEQLIDHMANTVEADGSNDEGYEAAEEGLGDEDEKRKISAIRSYRDVMKLCAAHLPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 PPLEQLIDHMANTVEADGSNDEGYEAAEEGLGDEDEKRKISAIRSYRDVMKLCAAHLPTE
40 50 60 70 80 90
220 230 240 250 260 270
pF1KSD SDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESSTDLEELKNADWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESSTDLEELKNADWA
100 110 120 130 140 150
280 290 300 310 320 330
pF1KSD RFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 RFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIP
160 170 180 190 200 210
340 350 360 370 380 390
pF1KSD PRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 PRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEE
220 230 240 250 260 270
400 410 420 430 440 450
pF1KSD IRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQR
:::::: ::::::::::::::::::::::::::::::::::::::::
CCDS45 IRRSRL--------------DVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQR
280 290 300 310
460 470 480 490 500 510
pF1KSD KKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTP
320 330 340 350 360 370
520 530 540 550 560 570
pF1KSD QPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVECLALTVEEVMHIRQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVECLALTVEEVMHIRQVL
380 390 400 410 420 430
580 590 600 610 620 630
pF1KSD VKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCKKMRLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCKKMRLPS
440 450 460 470 480 490
640 650 660 670 680 690
pF1KSD KPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPK
500 510 520 530 540 550
700 710 720 730 740 750
pF1KSD ELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSPGPSEYCPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSPGPSEYCPSE
560 570 580 590 600 610
pF1KSD RTISEI
::::::
CCDS45 RTISEI
620
>>CCDS32516.1 SPIRE2 gene_id:84501|Hs108|chr16 (714 aa)
initn: 1598 init1: 644 opt: 1555 Z-score: 1305.9 bits: 252.3 E(32554): 2e-66
Smith-Waterman score: 1747; 43.3% identity (67.1% similar) in 748 aa overlap (27-738:5-705)
10 20 30 40 50
pF1KSD MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGS-RDA---LSLEEILRLYNQPINEE
:. ::::.:. : :::::.:. :.::.:::
CCDS32 MARAGSCGGAAAGAGRPEPWELSLEEVLKAYEQPLNEE
10 20 30
60 70 80 90 100 110
pF1KSD QAWAVCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLG
::::::.: : .::.. : .:.:..... . ::.: . .:.:: .. :.
CCDS32 QAWAVCFQGCRGLRGS-----PGRRLRDTGDLLLRGDGSV--GAREPEAAEPATMVVPLA
40 50 60 70 80 90
120 130 140 150 160 170
pF1KSD YSQCMETEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEA
: :.....:::. ::.:::.:: :.::::::: ::.::: ::: . :.: : :
CCDS32 SS---EAQTVQSLGFAIYRALDWGLDESEERELSPQLERLIDLMAN----NDSEDSGCGA
100 110 120 130 140
180 190 200 210 220 230
pF1KSD AEEGLGDEDEKRKIS----AIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELH
:.:: : .:... ..:.. ..:.::::.: : ::::::::::.::.::.
CCDS32 ADEGYGGPEEEEEAEGVPRSVRTFAQAMRLCAARLTDPRGAQAHYQAVCRALFVETLELR
150 160 170 180 190 200
240 250 260 270 280 290
pF1KSD TFLTKIKSAKENLKKIQEMEKSDESS-TDLEELKNADWARFWVQVMRDLRNGVKLKKVQE
.::.... ::: :.:..: : :. ..:. : ..::::.:::.::.:: :::::::::
CCDS32 AFLARVREAKEMLQKLREDEPHLETPRAELDSLGHTDWARLWVQLMRELRRGVKLKKVQE
210 220 230 240 250 260
300 310 320 330 340 350
pF1KSD RQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPL
...:::: :.::::.::::.::: . : ::::::.::::::.::.:::.:::::::::::
CCDS32 QEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPL
270 280 290 300 310 320
360 370 380 390 400 410
pF1KSD NPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSD
. :: :.:.: ::. :::::.:::::: ::.:::: : : : .. : :.
CCDS32 KQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPV-----RGEGWAARGFG-SLPCILNA
330 340 350 360 370
420 430 440 450 460 470
pF1KSD VTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDS-SESEEE
. .. . .. :....: : : : : : ::.::::::.. . ::::
CCDS32 CSGDAKSTSCINLSVTDAG--------G---SAQRPRPRV-LLKAPTLAEMEEMNTSEEE
380 390 400 410 420
480 490 500 510 520
pF1KSD TLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRR----H----
. . . . :: :. . .. :.. . : :.: : .::. : :
CCDS32 ESPCGEVTLKRDRSFSEHDL---AQLRSEVASGLQ-SATHPPGGTEPPRPRAGSAHVWRP
430 440 450 460 470 480
530 540 550 560
pF1KSD -SIEKET-PTNVRQFLPP---SRQSS-----RSLE--------EFCYPVECLALTVEEVM
: .. : :..: . : .: :: :. :: .::: :::::::::
CCDS32 GSRDQGTCPASVSDPSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEEVM
490 500 510 520 530 540
570 580 590 600 610 620
pF1KSD HIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCK
.:.::::::.::. : :.....:::::.: :::.. : .:.: .: :::: ::..:
CCDS32 DVRRVLVKAEMEKFLQNKELFSSLKKGKICCCCRAK-FPLFSWPPSCLFCKRAVCTSCSI
550 560 570 580 590 600
630 640 650 660 670 680
pF1KSD KMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDE
::..::: .. .:...:: . :: :.:. :.. :.: . . .: :
CCDS32 KMKMPSKKFGHIPVYTLGFESPQR---------VSAAKTAPIQRRDIFQSLQGPQWQSVE
610 620 630 640 650
690 700 710 720 730 740
pF1KSD ELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSPGPS
: ::. . .:: .: .:..... :::.:. . : : .:.:::.:.
CCDS32 E-AFPHIYSHGCVLKDVCSECTSFVADVVRSSRKSVDVLNTTPRRSRQTQSLYIPNTRTL
660 670 680 690 700 710
750
pF1KSD EYCPSERTISEI
CCDS32 DFK
756 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:07:25 2016 done: Thu Nov 3 05:07:25 2016
Total Scan time: 4.780 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]