Result of FASTA (omim) for
pF1KSDA1135
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1135, 756 aa
1>>>pF1KSDA1135 756 - 756 aa - 756 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0368+/-0.00032; mu= 8.4616+/- 0.020
mean_var=153.9558+/-30.739, 0's: 0 Z-trim(120.4): 19 B-trim: 329 in 1/58
Lambda= 0.103366
statistics sampled from 35599 (35618) to 35599 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.418), width: 16
Scan time: 13.380
The best scores are: opt bits E(85289)
NP_001122098 (OMIM: 609216) protein spire homolog ( 756) 5039 763.5 0
XP_011524003 (OMIM: 609216) PREDICTED: protein spi ( 814) 3602 549.2 2.5e-155
XP_011524005 (OMIM: 609216) PREDICTED: protein spi ( 484) 3099 474.0 6.2e-133
XP_011524004 (OMIM: 609216) PREDICTED: protein spi ( 694) 2767 424.6 6.7e-118
NP_064533 (OMIM: 609216) protein spire homolog 1 i ( 742) 2688 412.9 2.5e-114
XP_005258179 (OMIM: 609216) PREDICTED: protein spi ( 800) 2684 412.3 4e-114
NP_001122099 (OMIM: 609216) protein spire homolog ( 622) 2315 357.2 1.2e-97
NP_115827 (OMIM: 609217) protein spire homolog 2 [ ( 714) 1555 243.9 1.8e-63
XP_011521681 (OMIM: 609217) PREDICTED: protein spi ( 661) 1519 238.5 6.8e-62
XP_016879269 (OMIM: 609217) PREDICTED: protein spi ( 629) 1517 238.2 8.1e-62
XP_016879268 (OMIM: 609217) PREDICTED: protein spi ( 629) 1517 238.2 8.1e-62
XP_011521682 (OMIM: 609217) PREDICTED: protein spi ( 642) 1511 237.3 1.5e-61
XP_011521683 (OMIM: 609217) PREDICTED: protein spi ( 642) 1511 237.3 1.5e-61
XP_011521686 (OMIM: 609217) PREDICTED: protein spi ( 593) 1344 212.4 4.5e-54
XP_016879270 (OMIM: 609217) PREDICTED: protein spi ( 595) 1137 181.5 8.8e-45
XP_011521687 (OMIM: 609217) PREDICTED: protein spi ( 441) 1093 174.9 6.5e-43
>>NP_001122098 (OMIM: 609216) protein spire homolog 1 is (756 aa)
initn: 5039 init1: 5039 opt: 5039 Z-score: 4068.2 bits: 763.5 E(85289): 0
Smith-Waterman score: 5039; 100.0% identity (100.0% similar) in 756 aa overlap (1-756:1-756)
10 20 30 40 50 60
pF1KSD MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
670 680 690 700 710 720
730 740 750
pF1KSD VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
::::::::::::::::::::::::::::::::::::
NP_001 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
730 740 750
>>XP_011524003 (OMIM: 609216) PREDICTED: protein spire h (814 aa)
initn: 3602 init1: 3602 opt: 3602 Z-score: 2909.6 bits: 549.2 E(85289): 2.5e-155
Smith-Waterman score: 4736; 92.6% identity (92.6% similar) in 788 aa overlap (1-730:1-788)
10 20 30 40 50 60
pF1KSD MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
490 500 510 520 530 540
pF1KSD QSSRSL------------------------------------------------------
::::::
XP_011 QSSRSLVPRITSVWPRTPFRPLFSTIQTASLLSSHPFEAAMFGVAGAMYYLCERAFTSRW
550 560 570 580 590 600
550 560 570 580 590 600
pF1KSD ----EEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSSKEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRF
610 620 630 640 650 660
610 620 630 640 650 660
pF1KSD SFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAH
670 680 690 700 710 720
670 680 690 700 710 720
pF1KSD HRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVL
730 740 750 760 770 780
730 740 750
pF1KSD ANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
::::::::
XP_011 ANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
790 800 810
>>XP_011524005 (OMIM: 609216) PREDICTED: protein spire h (484 aa)
initn: 3149 init1: 3099 opt: 3099 Z-score: 2507.6 bits: 474.0 E(85289): 6.2e-133
Smith-Waterman score: 3099; 97.5% identity (99.0% similar) in 482 aa overlap (1-482:1-482)
10 20 30 40 50 60
pF1KSD MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
::::::::::::::::::::::::::::::::::::::::::::::::. .: ....
XP_011 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEKCSLTQTSAPYC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
.:
XP_011 MSGI
>>XP_011524004 (OMIM: 609216) PREDICTED: protein spire h (694 aa)
initn: 2767 init1: 2767 opt: 2767 Z-score: 2237.6 bits: 424.6 E(85289): 6.7e-118
Smith-Waterman score: 3901; 91.3% identity (91.3% similar) in 668 aa overlap (121-730:1-668)
100 110 120 130 140 150
pF1KSD WRDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIESLGIIIYKALDYGLKENEERELS
::::::::::::::::::::::::::::::
XP_011 METEVIESLGIIIYKALDYGLKENEERELS
10 20 30
160 170 180 190 200 210
pF1KSD PPLEQLIDHMANTVEADGSNDEGYEAAEEGLGDEDEKRKISAIRSYRDVMKLCAAHLPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPLEQLIDHMANTVEADGSNDEGYEAAEEGLGDEDEKRKISAIRSYRDVMKLCAAHLPTE
40 50 60 70 80 90
220 230 240 250 260 270
pF1KSD SDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESSTDLEELKNADWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESSTDLEELKNADWA
100 110 120 130 140 150
280 290 300 310 320 330
pF1KSD RFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIP
160 170 180 190 200 210
340 350 360 370 380 390
pF1KSD PRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEE
220 230 240 250 260 270
400 410 420 430 440 450
pF1KSD IRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQR
280 290 300 310 320 330
460 470 480 490 500 510
pF1KSD KKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTP
340 350 360 370 380 390
520 530 540
pF1KSD QPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSL------------------------
::::::::::::::::::::::::::::::::::::
XP_011 QPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLVPRITSVWPRTPFRPLFSTIQTAS
400 410 420 430 440 450
550 560 570
pF1KSD ----------------------------------EEFCYPVECLALTVEEVMHIRQVLVK
::::::::::::::::::::::::::
XP_011 LLSSHPFEAAMFGVAGAMYYLCERAFTSRWKSSKEEFCYPVECLALTVEEVMHIRQVLVK
460 470 480 490 500 510
580 590 600 610 620 630
pF1KSD AELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKP
520 530 540 550 560 570
640 650 660 670 680 690
pF1KSD YSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPKEL
580 590 600 610 620 630
700 710 720 730 740 750
pF1KSD MEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSPGPSEYCPSERT
::::::::::::::::::::::::::::::::::::::
XP_011 MEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSPGPSEYCPSERT
640 650 660 670 680 690
pF1KSD ISEI
XP_011 ISEI
>>NP_064533 (OMIM: 609216) protein spire homolog 1 isofo (742 aa)
initn: 4935 init1: 2647 opt: 2688 Z-score: 2173.5 bits: 412.9 E(85289): 2.5e-114
Smith-Waterman score: 4911; 98.1% identity (98.1% similar) in 756 aa overlap (1-756:1-742)
10 20 30 40 50 60
pF1KSD MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
:::::::::::::::::::::::::::::::::::: ::::::::::
NP_064 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL--------------DVTTPESTKN
370 380 390 400
430 440 450 460 470 480
pF1KSD LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
650 660 670 680 690 700
730 740 750
pF1KSD VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
::::::::::::::::::::::::::::::::::::
NP_064 VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
710 720 730 740
>>XP_005258179 (OMIM: 609216) PREDICTED: protein spire h (800 aa)
initn: 4072 init1: 2647 opt: 2684 Z-score: 2169.8 bits: 412.3 E(85289): 4e-114
Smith-Waterman score: 4704; 91.0% identity (91.0% similar) in 802 aa overlap (1-744:1-788)
10 20 30 40 50 60
pF1KSD MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
:::::::::::::::::::::::::::::::::::: ::::::::::
XP_005 PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRL--------------DVTTPESTKN
370 380 390 400
430 440 450 460 470 480
pF1KSD LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
470 480 490 500 510 520
pF1KSD QSSRSL------------------------------------------------------
::::::
XP_005 QSSRSLVPRITSVWPRTPFRPLFSTIQTASLLSSHPFEAAMFGVAGAMYYLCERAFTSRW
530 540 550 560 570 580
550 560 570 580 590 600
pF1KSD ----EEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSSKEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRF
590 600 610 620 630 640
610 620 630 640 650 660
pF1KSD SFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAH
650 660 670 680 690 700
670 680 690 700 710 720
pF1KSD HRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVL
710 720 730 740 750 760
730 740 750
pF1KSD ANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
::::::::::::::::::::::
XP_005 ANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
770 780 790 800
>>NP_001122099 (OMIM: 609216) protein spire homolog 1 is (622 aa)
initn: 4100 init1: 2302 opt: 2315 Z-score: 1874.1 bits: 357.2 E(85289): 1.2e-97
Smith-Waterman score: 4076; 97.8% identity (97.8% similar) in 636 aa overlap (121-756:1-622)
100 110 120 130 140 150
pF1KSD WRDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIESLGIIIYKALDYGLKENEERELS
::::::::::::::::::::::::::::::
NP_001 METEVIESLGIIIYKALDYGLKENEERELS
10 20 30
160 170 180 190 200 210
pF1KSD PPLEQLIDHMANTVEADGSNDEGYEAAEEGLGDEDEKRKISAIRSYRDVMKLCAAHLPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLEQLIDHMANTVEADGSNDEGYEAAEEGLGDEDEKRKISAIRSYRDVMKLCAAHLPTE
40 50 60 70 80 90
220 230 240 250 260 270
pF1KSD SDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESSTDLEELKNADWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESSTDLEELKNADWA
100 110 120 130 140 150
280 290 300 310 320 330
pF1KSD RFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIP
160 170 180 190 200 210
340 350 360 370 380 390
pF1KSD PRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEE
220 230 240 250 260 270
400 410 420 430 440 450
pF1KSD IRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQR
:::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 IRRSRL--------------DVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQR
280 290 300 310
460 470 480 490 500 510
pF1KSD KKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLLRAPTLAELDSSESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTP
320 330 340 350 360 370
520 530 540 550 560 570
pF1KSD QPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVECLALTVEEVMHIRQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPERRQPPQRRHSIEKETPTNVRQFLPPSRQSSRSLEEFCYPVECLALTVEEVMHIRQVL
380 390 400 410 420 430
580 590 600 610 620 630
pF1KSD VKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCKKMRLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCKKMRLPS
440 450 460 470 480 490
640 650 660 670 680 690
pF1KSD KPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPK
500 510 520 530 540 550
700 710 720 730 740 750
pF1KSD ELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSPGPSEYCPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSPGPSEYCPSE
560 570 580 590 600 610
pF1KSD RTISEI
::::::
NP_001 RTISEI
620
>>NP_115827 (OMIM: 609217) protein spire homolog 2 [Homo (714 aa)
initn: 1598 init1: 644 opt: 1555 Z-score: 1260.7 bits: 243.9 E(85289): 1.8e-63
Smith-Waterman score: 1747; 43.3% identity (67.1% similar) in 748 aa overlap (27-738:5-705)
10 20 30 40 50
pF1KSD MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGS-RDA---LSLEEILRLYNQPINEE
:. ::::.:. : :::::.:. :.::.:::
NP_115 MARAGSCGGAAAGAGRPEPWELSLEEVLKAYEQPLNEE
10 20 30
60 70 80 90 100 110
pF1KSD QAWAVCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLG
::::::.: : .::.. : .:.:..... . ::.: . .:.:: .. :.
NP_115 QAWAVCFQGCRGLRGS-----PGRRLRDTGDLLLRGDGSV--GAREPEAAEPATMVVPLA
40 50 60 70 80 90
120 130 140 150 160 170
pF1KSD YSQCMETEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEA
: :.....:::. ::.:::.:: :.::::::: ::.::: ::: . :.: : :
NP_115 SS---EAQTVQSLGFAIYRALDWGLDESEERELSPQLERLIDLMAN----NDSEDSGCGA
100 110 120 130 140
180 190 200 210 220 230
pF1KSD AEEGLGDEDEKRKIS----AIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELH
:.:: : .:... ..:.. ..:.::::.: : ::::::::::.::.::.
NP_115 ADEGYGGPEEEEEAEGVPRSVRTFAQAMRLCAARLTDPRGAQAHYQAVCRALFVETLELR
150 160 170 180 190 200
240 250 260 270 280 290
pF1KSD TFLTKIKSAKENLKKIQEMEKSDESS-TDLEELKNADWARFWVQVMRDLRNGVKLKKVQE
.::.... ::: :.:..: : :. ..:. : ..::::.:::.::.:: :::::::::
NP_115 AFLARVREAKEMLQKLREDEPHLETPRAELDSLGHTDWARLWVQLMRELRRGVKLKKVQE
210 220 230 240 250 260
300 310 320 330 340 350
pF1KSD RQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPL
...:::: :.::::.::::.::: . : ::::::.::::::.::.:::.:::::::::::
NP_115 QEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPL
270 280 290 300 310 320
360 370 380 390 400 410
pF1KSD NPVSARKLKPTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSD
. :: :.:.: ::. :::::.:::::: ::.:::: : : : .. : :.
NP_115 KQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPV-----RGEGWAARGFG-SLPCILNA
330 340 350 360 370
420 430 440 450 460 470
pF1KSD VTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDS-SESEEE
. .. . .. :....: : : : : : ::.::::::.. . ::::
NP_115 CSGDAKSTSCINLSVTDAG--------G---SAQRPRPRV-LLKAPTLAEMEEMNTSEEE
380 390 400 410 420
480 490 500 510 520
pF1KSD TLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRR----H----
. . . . :: :. . .. :.. . : :.: : .::. : :
NP_115 ESPCGEVTLKRDRSFSEHDL---AQLRSEVASGLQ-SATHPPGGTEPPRPRAGSAHVWRP
430 440 450 460 470 480
530 540 550 560
pF1KSD -SIEKET-PTNVRQFLPP---SRQSS-----RSLE--------EFCYPVECLALTVEEVM
: .. : :..: . : .: :: :. :: .::: :::::::::
NP_115 GSRDQGTCPASVSDPSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEEVM
490 500 510 520 530 540
570 580 590 600 610 620
pF1KSD HIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCK
.:.::::::.::. : :.....:::::.: :::.. : .:.: .: :::: ::..:
NP_115 DVRRVLVKAEMEKFLQNKELFSSLKKGKICCCCRAK-FPLFSWPPSCLFCKRAVCTSCSI
550 560 570 580 590 600
630 640 650 660 670 680
pF1KSD KMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDE
::..::: .. .:...:: . :: :.:. :.. :.: . . .: :
NP_115 KMKMPSKKFGHIPVYTLGFESPQR---------VSAAKTAPIQRRDIFQSLQGPQWQSVE
610 620 630 640 650
690 700 710 720 730 740
pF1KSD ELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSPGPS
: ::. . .:: .: .:..... :::.:. . : : .:.:::.:.
NP_115 E-AFPHIYSHGCVLKDVCSECTSFVADVVRSSRKSVDVLNTTPRRSRQTQSLYIPNTRTL
660 670 680 690 700 710
750
pF1KSD EYCPSERTISEI
NP_115 DFK
>>XP_011521681 (OMIM: 609217) PREDICTED: protein spire h (661 aa)
initn: 1454 init1: 644 opt: 1519 Z-score: 1232.1 bits: 238.5 E(85289): 6.8e-62
Smith-Waterman score: 1557; 42.5% identity (66.4% similar) in 663 aa overlap (107-738:29-652)
80 90 100 110 120 130
pF1KSD QPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIESLGIIIYKA
:: .. :. : :.....:::. ::.:
XP_011 MQCIQTVEIREKTMKMAGGKRYVKYSNKEPATMVVPLASS---EAQTVQSLGFAIYRA
10 20 30 40 50
140 150 160 170 180 190
pF1KSD LDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEGLGDEDEKRKIS----A
::.:: :.::::::: ::.::: ::: . :.: : ::.:: : .:... .
XP_011 LDWGLDESEERELSPQLERLIDLMAN----NDSEDSGCGAADEGYGGPEEEEEAEGVPRS
60 70 80 90 100 110
200 210 220 230 240 250
pF1KSD IRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEME
.:.. ..:.::::.: : ::::::::::.::.::..::.... ::: :.:..: :
XP_011 VRTFAQAMRLCAARLTDPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLREDE
120 130 140 150 160 170
260 270 280 290 300 310
pF1KSD KSDESS-TDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMD
:. ..:. : ..::::.:::.::.:: :::::::::...:::: :.::::.::::.
XP_011 PHLETPRAELDSLGHTDWARLWVQLMRELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQ
180 190 200 210 220 230
320 330 340 350 360 370
pF1KSD DIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHE
::: . : ::::::.::::::.::.:::.:::::::::::. :: :.:.: ::. :::::
XP_011 DIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPKQRSLHE
240 250 260 270 280 290
380 390 400 410 420 430
pF1KSD RILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVESSMVNGGL
.:::::: ::.:::: : : : .. : :. . .. . .. :....:
XP_011 KILEEIKQERRLRPV-----RGEGWAARGFG-SLPCILNACSGDAKSTSCINLSVTDAG-
300 310 320 330 340
440 450 460 470 480
pF1KSD TSQTKENGLSTSQQVPAQRKKLLRAPTLAELD---SSESEEE-----TLHKSTSSSSVSP
: : : : ::.::::::.. .:: :: ::... : : .
XP_011 ----------GSAQRPRPRV-LLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDL
350 360 370 380 390
490 500 510 520 530
pF1KSD SFPEEPVLEAVSTRKKPPKFLPISSTPQPERR-----QPPQRRHSIEKETPTNVRQFLPP
. . : .... .:: . :.:. .: .: .. . .. . :
XP_011 AQLRSEVASGLQSATHPPG---GTEPPRPRAGSAHVWRPGSRDQGTCPASVSDPSHPLLS
400 410 420 430 440 450
540 550 560 570 580
pF1KSD SRQSS-----RSLE--------EFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIY
.: :: :. :: .::: ::::::::: .:.::::::.::. : :...
XP_011 NRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEEVMDVRRVLVKAEMEKFLQNKELF
460 470 480 490 500 510
590 600 610 620 630 640
pF1KSD TALKKGKLCFCCRTRRFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSA
..:::::.: :::.. : .:.: .: :::: ::..: ::..::: .. .:...:: .
XP_011 SSLKKGKICCCCRAK-FPLFSWPPSCLFCKRAVCTSCSIKMKMPSKKFGHIPVYTLGFES
520 530 540 550 560
650 660 670 680 690 700
pF1KSD LQRGESSMRSEKPSTAHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDC
:: :.:. :.. :.: . . .: :: ::. . .:: .:
XP_011 PQR---------VSAAKTAPIQRRDIFQSLQGPQWQSVEE-AFPHIYSHGCVLKDVCSEC
570 580 590 600 610
710 720 730 740 750
pF1KSD KKFISEIISSSRRSLVLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
.:..... :::.:. . : : .:.:::.:.
XP_011 TSFVADVVRSSRKSVDVLNTTPRRSRQTQSLYIPNTRTLDFK
620 630 640 650 660
>>XP_016879269 (OMIM: 609217) PREDICTED: protein spire h (629 aa)
initn: 1454 init1: 644 opt: 1517 Z-score: 1230.9 bits: 238.2 E(85289): 8.1e-62
Smith-Waterman score: 1555; 43.8% identity (67.2% similar) in 649 aa overlap (122-738:9-620)
100 110 120 130 140 150
pF1KSD RDGAVTLAPAADDAGEPPPVAGKLGYSQCMETEVIESLGIIIYKALDYGLKENEERELSP
:.....:::. ::.:::.:: :.:::::::
XP_016 MVVPLASSEAQTVQSLGFAIYRALDWGLDESEERELSP
10 20 30
160 170 180 190 200
pF1KSD PLEQLIDHMANTVEADGSNDEGYEAAEEGLGDEDEKRKIS----AIRSYRDVMKLCAAHL
::.::: ::: . :.: : ::.:: : .:... ..:.. ..:.::::.:
XP_016 QLERLIDLMAN----NDSEDSGCGAADEGYGGPEEEEEAEGVPRSVRTFAQAMRLCAARL
40 50 60 70 80 90
210 220 230 240 250 260
pF1KSD PTESDAPNHYQAVCRALFAETMELHTFLTKIKSAKENLKKIQEMEKSDESS-TDLEELKN
: ::::::::::.::.::..::.... ::: :.:..: : :. ..:. : .
XP_016 TDPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLREDEPHLETPRAELDSLGH
100 110 120 130 140 150
270 280 290 300 310 320
pF1KSD ADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIEYQLTPYEMLMDDIRCKRYTLRKVMVN
.::::.:::.::.:: :::::::::...:::: :.::::.::::.::: . : ::::::.
XP_016 TDWARLWVQLMRELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVD
160 170 180 190 200 210
330 340 350 360 370 380
pF1KSD GDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLKPTPPRPRSLHERILEEIKAERKLRPV
::::::.::.:::.:::::::::::. :: :.:.: ::. :::::.:::::: ::.::::
XP_016 GDIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPV
220 230 240 250 260 270
390 400 410 420 430 440
pF1KSD SPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQV
: : : .. : :. . .. . .. :....: : : :
XP_016 RGEG-----WAARGFG-SLPCILNACSGDAKSTSCINLSVTDAG--------G---SAQR
280 290 300 310
450 460 470 480 490 500
pF1KSD PAQRKKLLRAPTLAELDS-SESEEETLHKSTSSSSVSPSFPEEPVLEAVSTRKKPPKFLP
: : ::.::::::.. . :::: . . . . :: :. . .. :.. . :
XP_016 PRPRV-LLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSEH---DLAQLRSEVASGLQ
320 330 340 350 360 370
510 520 530 540
pF1KSD ISSTPQPERRQPPQRR----H-----SIEKET-PTNVRQFLPP---SRQSS-----RSLE
:.: : .::. : : : .. : :..: . : .: :: :.
XP_016 -SATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASVSDPSHPLLSNRGSSGDRPEASMT
380 390 400 410 420 430
550 560 570 580 590
pF1KSD --------EFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRT
:: .::: ::::::::: .:.::::::.::. : :.....:::::.: :::.
XP_016 PDAKHLWLEFSHPVESLALTVEEVMDVRRVLVKAEMEKFLQNKELFSSLKKGKICCCCRA
440 450 460 470 480 490
600 610 620 630 640 650
pF1KSD RRFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPS
. : .:.: .: :::: ::..: ::..::: .. .:...:: . :: :
XP_016 K-FPLFSWPPSCLFCKRAVCTSCSIKMKMPSKKFGHIPVYTLGFESPQR---------VS
500 510 520 530 540
660 670 680 690 700 710
pF1KSD TAHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRS
.:. :.. :.: . . .: :: ::. . .:: .: .:..... :::.:
XP_016 AAKTAPIQRRDIFQSLQGPQWQSVEE-AFPHIYSHGCVLKDVCSECTSFVADVVRSSRKS
550 560 570 580 590 600
720 730 740 750
pF1KSD LVLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI
. . : : .:.:::.:.
XP_016 VDVLNTTPRRSRQTQSLYIPNTRTLDFK
610 620
756 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:07:26 2016 done: Thu Nov 3 05:07:28 2016
Total Scan time: 13.380 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]