FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1142, 438 aa 1>>>pF1KSDA1142 438 - 438 aa - 438 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.2414+/-0.000498; mu= -16.5996+/- 0.031 mean_var=638.0566+/-133.320, 0's: 0 Z-trim(123.1): 1682 B-trim: 0 in 0/62 Lambda= 0.050774 statistics sampled from 40119 (42355) to 40119 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.497), width: 16 Scan time: 9.730 The best scores are: opt bits E(85289) NP_001014834 (OMIM: 605451) serine/threonine-prote ( 438) 2972 232.4 1.8e-60 XP_011524622 (OMIM: 605451) PREDICTED: serine/thre ( 438) 2972 232.4 1.8e-60 NP_001014835 (OMIM: 605451) serine/threonine-prote ( 438) 2972 232.4 1.8e-60 XP_011524619 (OMIM: 605451) PREDICTED: serine/thre ( 591) 2503 198.2 4.8e-50 XP_011524621 (OMIM: 605451) PREDICTED: serine/thre ( 591) 2503 198.2 4.8e-50 XP_011524618 (OMIM: 605451) PREDICTED: serine/thre ( 591) 2503 198.2 4.8e-50 NP_001014832 (OMIM: 605451) serine/threonine-prote ( 591) 2503 198.2 4.8e-50 XP_011524620 (OMIM: 605451) PREDICTED: serine/thre ( 591) 2503 198.2 4.8e-50 NP_005875 (OMIM: 605451) serine/threonine-protein ( 591) 2503 198.2 4.8e-50 NP_001014831 (OMIM: 605451) serine/threonine-prote ( 591) 2503 198.2 4.8e-50 XP_016883453 (OMIM: 608038) PREDICTED: serine/thre ( 719) 1730 141.7 6.1e-33 XP_016883450 (OMIM: 608038) PREDICTED: serine/thre ( 719) 1730 141.7 6.1e-33 XP_016883452 (OMIM: 608038) PREDICTED: serine/thre ( 719) 1730 141.7 6.1e-33 NP_065074 (OMIM: 608038) serine/threonine-protein ( 719) 1730 141.7 6.1e-33 XP_016883449 (OMIM: 608038) PREDICTED: serine/thre ( 719) 1730 141.7 6.1e-33 NP_817127 (OMIM: 608038) serine/threonine-protein ( 719) 1730 141.7 6.1e-33 XP_016883454 (OMIM: 608038) PREDICTED: serine/thre ( 719) 1730 141.7 6.1e-33 XP_016883451 (OMIM: 608038) PREDICTED: serine/thre ( 719) 1730 141.7 6.1e-33 NP_064553 (OMIM: 608110) serine/threonine-protein ( 681) 1537 127.5 1.1e-28 NP_001263646 (OMIM: 608110) serine/threonine-prote ( 681) 1537 127.5 1.1e-28 NP_001263647 (OMIM: 608110) serine/threonine-prote ( 636) 1099 95.4 4.6e-19 NP_002568 (OMIM: 605022) serine/threonine-protein ( 524) 1088 94.5 7e-19 XP_016861990 (OMIM: 605022) PREDICTED: serine/thre ( 524) 1088 94.5 7e-19 XP_011511172 (OMIM: 605022) PREDICTED: serine/thre ( 524) 1088 94.5 7e-19 NP_001311261 (OMIM: 300142,300558) serine/threonin ( 544) 1085 94.3 8.4e-19 NP_001311263 (OMIM: 300142,300558) serine/threonin ( 544) 1085 94.3 8.4e-19 NP_001311255 (OMIM: 300142,300558) serine/threonin ( 544) 1085 94.3 8.4e-19 XP_016885050 (OMIM: 300142,300558) PREDICTED: seri ( 544) 1085 94.3 8.4e-19 NP_001311260 (OMIM: 300142,300558) serine/threonin ( 544) 1085 94.3 8.4e-19 NP_001311259 (OMIM: 300142,300558) serine/threonin ( 544) 1085 94.3 8.4e-19 NP_001121639 (OMIM: 300142,300558) serine/threonin ( 544) 1085 94.3 8.4e-19 NP_002569 (OMIM: 300142,300558) serine/threonine-p ( 544) 1085 94.3 8.4e-19 NP_001121638 (OMIM: 300142,300558) serine/threonin ( 544) 1085 94.3 8.4e-19 NP_001311254 (OMIM: 300142,300558) serine/threonin ( 544) 1085 94.3 8.4e-19 NP_001311257 (OMIM: 300142,300558) serine/threonin ( 559) 1085 94.3 8.5e-19 XP_016885046 (OMIM: 300142,300558) PREDICTED: seri ( 559) 1085 94.3 8.5e-19 NP_001311262 (OMIM: 300142,300558) serine/threonin ( 559) 1085 94.3 8.5e-19 NP_001311256 (OMIM: 300142,300558) serine/threonin ( 559) 1085 94.3 8.5e-19 NP_001311258 (OMIM: 300142,300558) serine/threonin ( 559) 1085 94.3 8.5e-19 NP_001121645 (OMIM: 300142,300558) serine/threonin ( 559) 1085 94.3 8.5e-19 NP_001121644 (OMIM: 300142,300558) serine/threonin ( 565) 1085 94.3 8.6e-19 XP_016885052 (OMIM: 300142,300558) PREDICTED: seri ( 580) 1085 94.3 8.8e-19 NP_001121640 (OMIM: 300142,300558) serine/threonin ( 580) 1085 94.3 8.8e-19 XP_016873337 (OMIM: 602590) PREDICTED: serine/thre ( 545) 1073 93.4 1.5e-18 XP_016873336 (OMIM: 602590) PREDICTED: serine/thre ( 545) 1073 93.4 1.5e-18 XP_016873339 (OMIM: 602590) PREDICTED: serine/thre ( 545) 1073 93.4 1.5e-18 XP_016873335 (OMIM: 602590) PREDICTED: serine/thre ( 545) 1073 93.4 1.5e-18 XP_016873338 (OMIM: 602590) PREDICTED: serine/thre ( 545) 1073 93.4 1.5e-18 NP_002567 (OMIM: 602590) serine/threonine-protein ( 545) 1073 93.4 1.5e-18 XP_016885051 (OMIM: 300142,300558) PREDICTED: seri ( 533) 1022 89.7 2e-17 >>NP_001014834 (OMIM: 605451) serine/threonine-protein k (438 aa) initn: 2972 init1: 2972 opt: 2972 Z-score: 1206.7 bits: 232.4 E(85289): 1.8e-60 Smith-Waterman score: 2972; 100.0% identity (100.0% similar) in 438 aa overlap (1-438:1-438) 10 20 30 40 50 60 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAPSPGVLGPHASEPQLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAPSPGVLGPHASEPQLAP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLA 370 380 390 400 410 420 430 pF1KSD KAGPPASIVPLMRQNRTR :::::::::::::::::: NP_001 KAGPPASIVPLMRQNRTR 430 >>XP_011524622 (OMIM: 605451) PREDICTED: serine/threonin (438 aa) initn: 2972 init1: 2972 opt: 2972 Z-score: 1206.7 bits: 232.4 E(85289): 1.8e-60 Smith-Waterman score: 2972; 100.0% identity (100.0% similar) in 438 aa overlap (1-438:1-438) 10 20 30 40 50 60 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAPSPGVLGPHASEPQLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAPSPGVLGPHASEPQLAP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLA 370 380 390 400 410 420 430 pF1KSD KAGPPASIVPLMRQNRTR :::::::::::::::::: XP_011 KAGPPASIVPLMRQNRTR 430 >>NP_001014835 (OMIM: 605451) serine/threonine-protein k (438 aa) initn: 2972 init1: 2972 opt: 2972 Z-score: 1206.7 bits: 232.4 E(85289): 1.8e-60 Smith-Waterman score: 2972; 100.0% identity (100.0% similar) in 438 aa overlap (1-438:1-438) 10 20 30 40 50 60 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAPSPGVLGPHASEPQLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAPSPGVLGPHASEPQLAP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD IVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD VMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD VKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD PYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLA 370 380 390 400 410 420 430 pF1KSD KAGPPASIVPLMRQNRTR :::::::::::::::::: NP_001 KAGPPASIVPLMRQNRTR 430 >>XP_011524619 (OMIM: 605451) PREDICTED: serine/threonin (591 aa) initn: 2499 init1: 2499 opt: 2503 Z-score: 1019.5 bits: 198.2 E(85289): 4.8e-50 Smith-Waterman score: 2503; 90.3% identity (92.7% similar) in 424 aa overlap (15-438:173-591) 10 20 30 40 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE :. ..: .: : . .:: : . XP_011 EAGGGSGDRRRAGPEKRPKSSREGSGGPQESSRDKRPLSGPDVGTPQPAGLA----SGAK 150 160 170 180 190 50 60 70 80 90 100 pF1KSD ESARRPKPLVDPACITSIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP .: :: : . :: .:::::::::::::::::::::::::::::::::::: XP_011 LAAGRPFNTYPRADTDHPSRGA-QGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP 200 210 220 230 240 250 110 120 130 140 150 160 pF1KSD SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP 260 270 280 290 300 310 170 180 190 200 210 220 pF1KSD RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 320 330 340 350 360 370 230 240 250 260 270 280 pF1KSD VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 380 390 400 410 420 430 290 300 310 320 330 340 pF1KSD HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 440 450 460 470 480 490 350 360 370 380 390 400 pF1KSD IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP 500 510 520 530 540 550 410 420 430 pF1KSD AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR :::::::::::::::::::::::::::::::::: XP_011 AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 560 570 580 590 >-- initn: 522 init1: 475 opt: 493 Z-score: 223.7 bits: 51.0 E(85289): 1e-05 Smith-Waterman score: 493; 59.3% identity (72.9% similar) in 140 aa overlap (1-137:1-135) 10 20 30 40 50 60 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT 10 20 30 40 50 60 70 80 90 100 110 pF1KSD SIQPGAPKGEPHDVAPNGPSAGGLAIPQS---SSSSSRPPTRARGAPSPGVLGPHASEPQ :::::::: . . .: . :.:.. . . : .: . : .: : . .: . . XP_011 SIQPGAPKTIVR--GSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPA---RARQEN 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEG : . .: . :: : : XP_011 GMPEEPATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSSREGSGGPQESSR 120 130 140 150 160 170 >>XP_011524621 (OMIM: 605451) PREDICTED: serine/threonin (591 aa) initn: 2499 init1: 2499 opt: 2503 Z-score: 1019.5 bits: 198.2 E(85289): 4.8e-50 Smith-Waterman score: 2503; 90.3% identity (92.7% similar) in 424 aa overlap (15-438:173-591) 10 20 30 40 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE :. ..: .: : . .:: : . XP_011 EAGGGSGDRRRAGPEKRPKSSREGSGGPQESSRDKRPLSGPDVGTPQPAGLA----SGAK 150 160 170 180 190 50 60 70 80 90 100 pF1KSD ESARRPKPLVDPACITSIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP .: :: : . :: .:::::::::::::::::::::::::::::::::::: XP_011 LAAGRPFNTYPRADTDHPSRGA-QGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP 200 210 220 230 240 250 110 120 130 140 150 160 pF1KSD SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP 260 270 280 290 300 310 170 180 190 200 210 220 pF1KSD RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 320 330 340 350 360 370 230 240 250 260 270 280 pF1KSD VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 380 390 400 410 420 430 290 300 310 320 330 340 pF1KSD HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 440 450 460 470 480 490 350 360 370 380 390 400 pF1KSD IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP 500 510 520 530 540 550 410 420 430 pF1KSD AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR :::::::::::::::::::::::::::::::::: XP_011 AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 560 570 580 590 >-- initn: 522 init1: 475 opt: 493 Z-score: 223.7 bits: 51.0 E(85289): 1e-05 Smith-Waterman score: 493; 59.3% identity (72.9% similar) in 140 aa overlap (1-137:1-135) 10 20 30 40 50 60 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT 10 20 30 40 50 60 70 80 90 100 110 pF1KSD SIQPGAPKGEPHDVAPNGPSAGGLAIPQS---SSSSSRPPTRARGAPSPGVLGPHASEPQ :::::::: . . .: . :.:.. . . : .: . : .: : . .: . . XP_011 SIQPGAPKTIVR--GSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPA---RARQEN 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEG : . .: . :: : : XP_011 GMPEEPATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSSREGSGGPQESSR 120 130 140 150 160 170 >>XP_011524618 (OMIM: 605451) PREDICTED: serine/threonin (591 aa) initn: 2499 init1: 2499 opt: 2503 Z-score: 1019.5 bits: 198.2 E(85289): 4.8e-50 Smith-Waterman score: 2503; 90.3% identity (92.7% similar) in 424 aa overlap (15-438:173-591) 10 20 30 40 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE :. ..: .: : . .:: : . XP_011 EAGGGSGDRRRAGPEKRPKSSREGSGGPQESSRDKRPLSGPDVGTPQPAGLA----SGAK 150 160 170 180 190 50 60 70 80 90 100 pF1KSD ESARRPKPLVDPACITSIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP .: :: : . :: .:::::::::::::::::::::::::::::::::::: XP_011 LAAGRPFNTYPRADTDHPSRGA-QGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP 200 210 220 230 240 250 110 120 130 140 150 160 pF1KSD SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP 260 270 280 290 300 310 170 180 190 200 210 220 pF1KSD RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 320 330 340 350 360 370 230 240 250 260 270 280 pF1KSD VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 380 390 400 410 420 430 290 300 310 320 330 340 pF1KSD HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 440 450 460 470 480 490 350 360 370 380 390 400 pF1KSD IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP 500 510 520 530 540 550 410 420 430 pF1KSD AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR :::::::::::::::::::::::::::::::::: XP_011 AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 560 570 580 590 >-- initn: 522 init1: 475 opt: 493 Z-score: 223.7 bits: 51.0 E(85289): 1e-05 Smith-Waterman score: 493; 59.3% identity (72.9% similar) in 140 aa overlap (1-137:1-135) 10 20 30 40 50 60 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT 10 20 30 40 50 60 70 80 90 100 110 pF1KSD SIQPGAPKGEPHDVAPNGPSAGGLAIPQS---SSSSSRPPTRARGAPSPGVLGPHASEPQ :::::::: . . .: . :.:.. . . : .: . : .: : . .: . . XP_011 SIQPGAPKTIVR--GSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPA---RARQEN 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEG : . .: . :: : : XP_011 GMPEEPATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSSREGSGGPQESSR 120 130 140 150 160 170 >>NP_001014832 (OMIM: 605451) serine/threonine-protein k (591 aa) initn: 2499 init1: 2499 opt: 2503 Z-score: 1019.5 bits: 198.2 E(85289): 4.8e-50 Smith-Waterman score: 2503; 90.3% identity (92.7% similar) in 424 aa overlap (15-438:173-591) 10 20 30 40 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE :. ..: .: : . .:: : . NP_001 EAGGGSGDRRRAGPEKRPKSSREGSGGPQESSRDKRPLSGPDVGTPQPAGLA----SGAK 150 160 170 180 190 50 60 70 80 90 100 pF1KSD ESARRPKPLVDPACITSIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP .: :: : . :: .:::::::::::::::::::::::::::::::::::: NP_001 LAAGRPFNTYPRADTDHPSRGA-QGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP 200 210 220 230 240 250 110 120 130 140 150 160 pF1KSD SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP 260 270 280 290 300 310 170 180 190 200 210 220 pF1KSD RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 320 330 340 350 360 370 230 240 250 260 270 280 pF1KSD VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 380 390 400 410 420 430 290 300 310 320 330 340 pF1KSD HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 440 450 460 470 480 490 350 360 370 380 390 400 pF1KSD IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP 500 510 520 530 540 550 410 420 430 pF1KSD AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR :::::::::::::::::::::::::::::::::: NP_001 AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 560 570 580 590 >-- initn: 522 init1: 475 opt: 493 Z-score: 223.7 bits: 51.0 E(85289): 1e-05 Smith-Waterman score: 493; 59.3% identity (72.9% similar) in 140 aa overlap (1-137:1-135) 10 20 30 40 50 60 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT 10 20 30 40 50 60 70 80 90 100 110 pF1KSD SIQPGAPKGEPHDVAPNGPSAGGLAIPQS---SSSSSRPPTRARGAPSPGVLGPHASEPQ :::::::: . . .: . :.:.. . . : .: . : .: : . .: . . NP_001 SIQPGAPKTIVR--GSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPA---RARQEN 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEG : . .: . :: : : NP_001 GMPEEPATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSSREGSGGPQESSR 120 130 140 150 160 170 >>XP_011524620 (OMIM: 605451) PREDICTED: serine/threonin (591 aa) initn: 2499 init1: 2499 opt: 2503 Z-score: 1019.5 bits: 198.2 E(85289): 4.8e-50 Smith-Waterman score: 2503; 90.3% identity (92.7% similar) in 424 aa overlap (15-438:173-591) 10 20 30 40 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE :. ..: .: : . .:: : . XP_011 EAGGGSGDRRRAGPEKRPKSSREGSGGPQESSRDKRPLSGPDVGTPQPAGLA----SGAK 150 160 170 180 190 50 60 70 80 90 100 pF1KSD ESARRPKPLVDPACITSIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP .: :: : . :: .:::::::::::::::::::::::::::::::::::: XP_011 LAAGRPFNTYPRADTDHPSRGA-QGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP 200 210 220 230 240 250 110 120 130 140 150 160 pF1KSD SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP 260 270 280 290 300 310 170 180 190 200 210 220 pF1KSD RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 320 330 340 350 360 370 230 240 250 260 270 280 pF1KSD VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 380 390 400 410 420 430 290 300 310 320 330 340 pF1KSD HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 440 450 460 470 480 490 350 360 370 380 390 400 pF1KSD IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP 500 510 520 530 540 550 410 420 430 pF1KSD AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR :::::::::::::::::::::::::::::::::: XP_011 AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 560 570 580 590 >-- initn: 522 init1: 475 opt: 493 Z-score: 223.7 bits: 51.0 E(85289): 1e-05 Smith-Waterman score: 493; 59.3% identity (72.9% similar) in 140 aa overlap (1-137:1-135) 10 20 30 40 50 60 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT 10 20 30 40 50 60 70 80 90 100 110 pF1KSD SIQPGAPKGEPHDVAPNGPSAGGLAIPQS---SSSSSRPPTRARGAPSPGVLGPHASEPQ :::::::: . . .: . :.:.. . . : .: . : .: : . .: . . XP_011 SIQPGAPKTIVR--GSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPA---RARQEN 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEG : . .: . :: : : XP_011 GMPEEPATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSSREGSGGPQESSR 120 130 140 150 160 170 >>NP_005875 (OMIM: 605451) serine/threonine-protein kina (591 aa) initn: 2499 init1: 2499 opt: 2503 Z-score: 1019.5 bits: 198.2 E(85289): 4.8e-50 Smith-Waterman score: 2503; 90.3% identity (92.7% similar) in 424 aa overlap (15-438:173-591) 10 20 30 40 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE :. ..: .: : . .:: : . NP_005 EAGGGSGDRRRAGPEKRPKSSREGSGGPQESSRDKRPLSGPDVGTPQPAGLA----SGAK 150 160 170 180 190 50 60 70 80 90 100 pF1KSD ESARRPKPLVDPACITSIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP .: :: : . :: .:::::::::::::::::::::::::::::::::::: NP_005 LAAGRPFNTYPRADTDHPSRGA-QGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP 200 210 220 230 240 250 110 120 130 140 150 160 pF1KSD SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP 260 270 280 290 300 310 170 180 190 200 210 220 pF1KSD RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 320 330 340 350 360 370 230 240 250 260 270 280 pF1KSD VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 380 390 400 410 420 430 290 300 310 320 330 340 pF1KSD HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 440 450 460 470 480 490 350 360 370 380 390 400 pF1KSD IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP 500 510 520 530 540 550 410 420 430 pF1KSD AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR :::::::::::::::::::::::::::::::::: NP_005 AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 560 570 580 590 >-- initn: 522 init1: 475 opt: 493 Z-score: 223.7 bits: 51.0 E(85289): 1e-05 Smith-Waterman score: 493; 59.3% identity (72.9% similar) in 140 aa overlap (1-137:1-135) 10 20 30 40 50 60 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT 10 20 30 40 50 60 70 80 90 100 110 pF1KSD SIQPGAPKGEPHDVAPNGPSAGGLAIPQS---SSSSSRPPTRARGAPSPGVLGPHASEPQ :::::::: . . .: . :.:.. . . : .: . : .: : . .: . . NP_005 SIQPGAPKTIVR--GSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPA---RARQEN 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEG : . .: . :: : : NP_005 GMPEEPATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSSREGSGGPQESSR 120 130 140 150 160 170 >>NP_001014831 (OMIM: 605451) serine/threonine-protein k (591 aa) initn: 2499 init1: 2499 opt: 2503 Z-score: 1019.5 bits: 198.2 E(85289): 4.8e-50 Smith-Waterman score: 2503; 90.3% identity (92.7% similar) in 424 aa overlap (15-438:173-591) 10 20 30 40 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE :. ..: .: : . .:: : . NP_001 EAGGGSGDRRRAGPEKRPKSSREGSGGPQESSRDKRPLSGPDVGTPQPAGLA----SGAK 150 160 170 180 190 50 60 70 80 90 100 pF1KSD ESARRPKPLVDPACITSIQPGAPKGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP .: :: : . :: .:::::::::::::::::::::::::::::::::::: NP_001 LAAGRPFNTYPRADTDHPSRGA-QGEPHDVAPNGPSAGGLAIPQSSSSSSRPPTRARGAP 200 210 220 230 240 250 110 120 130 140 150 160 pF1KSD SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDP 260 270 280 290 300 310 170 180 190 200 210 220 pF1KSD RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 320 330 340 350 360 370 230 240 250 260 270 280 pF1KSD VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 380 390 400 410 420 430 290 300 310 320 330 340 pF1KSD HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 440 450 460 470 480 490 350 360 370 380 390 400 pF1KSD IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDP 500 510 520 530 540 550 410 420 430 pF1KSD AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR :::::::::::::::::::::::::::::::::: NP_001 AQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 560 570 580 590 >-- initn: 522 init1: 475 opt: 493 Z-score: 223.7 bits: 51.0 E(85289): 1e-05 Smith-Waterman score: 493; 59.3% identity (72.9% similar) in 140 aa overlap (1-137:1-135) 10 20 30 40 50 60 pF1KSD MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT 10 20 30 40 50 60 70 80 90 100 110 pF1KSD SIQPGAPKGEPHDVAPNGPSAGGLAIPQS---SSSSSRPPTRARGAPSPGVLGPHASEPQ :::::::: . . .: . :.:.. . . : .: . : .: : . .: . . NP_001 SIQPGAPKTIVR--GSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPA---RARQEN 70 80 90 100 110 120 130 140 150 160 170 pF1KSD LAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEG : . .: . :: : : NP_001 GMPEEPATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSSREGSGGPQESSR 120 130 140 150 160 170 438 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:08:43 2016 done: Thu Nov 3 05:08:45 2016 Total Scan time: 9.730 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]