FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1158, 215 aa 1>>>pF1KSDA1158 215 - 215 aa - 215 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2754+/-0.000988; mu= 14.2498+/- 0.059 mean_var=81.8437+/-16.643, 0's: 0 Z-trim(105.3): 56 B-trim: 0 in 0/51 Lambda= 0.141769 statistics sampled from 8293 (8338) to 8293 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.256), width: 16 Scan time: 2.030 The best scores are: opt bits E(32554) CCDS8442.1 SCN3B gene_id:55800|Hs108|chr11 ( 215) 1430 302.1 1.8e-82 CCDS12441.1 SCN1B gene_id:6324|Hs108|chr19 ( 218) 604 133.1 1.3e-31 CCDS46047.1 SCN1B gene_id:6324|Hs108|chr19 ( 268) 337 78.6 4.1e-15 >>CCDS8442.1 SCN3B gene_id:55800|Hs108|chr11 (215 aa) initn: 1430 init1: 1430 opt: 1430 Z-score: 1594.2 bits: 302.1 E(32554): 1.8e-82 Smith-Waterman score: 1430; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215) 10 20 30 40 50 60 pF1KSD MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 EWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD NVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS84 NVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIYC 130 140 150 160 170 180 190 200 210 pF1KSD YRKVSKAEEAAQENASDYLAIPSENKENSAVPVEE ::::::::::::::::::::::::::::::::::: CCDS84 YRKVSKAEEAAQENASDYLAIPSENKENSAVPVEE 190 200 210 >>CCDS12441.1 SCN1B gene_id:6324|Hs108|chr19 (218 aa) initn: 553 init1: 313 opt: 604 Z-score: 681.1 bits: 133.1 E(32554): 1.3e-31 Smith-Waterman score: 604; 49.5% identity (72.9% similar) in 214 aa overlap (10-215:5-218) 10 20 30 40 50 60 pF1KSD MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVV :: .: :: :::: :::::: : .:. :::: .: :..: : . CCDS12 MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFT 10 20 30 40 50 70 80 90 100 110 pF1KSD EWFYRPEGGKDFL-IYEYRNGHQEVESP--FQGRLQWNGS---KDLQDVSITVLNVTLND :: .: .: ..:. : .:.: ..: :.::. :::: :::::.:: . ::: : CCDS12 EWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD SGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLL :: : :.: : . :: .. ..... : ..:...:..:..:.:::::::.:.: ::.::. CCDS12 SGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLV 120 130 140 150 160 170 180 190 200 210 pF1KSD IEMIYCYRKVSKAEE-AAQENASDYLAIPSENKEN-SAVPVEE ::::::.:.. : : :::::::.:::: ::.::: ..: : : CCDS12 AEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE 180 190 200 210 >>CCDS46047.1 SCN1B gene_id:6324|Hs108|chr19 (268 aa) initn: 342 init1: 177 opt: 337 Z-score: 384.8 bits: 78.6 E(32554): 4.1e-15 Smith-Waterman score: 337; 43.2% identity (66.2% similar) in 148 aa overlap (10-151:5-151) 10 20 30 40 50 60 pF1KSD MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVV :: .: :: :::: :::::: : .:. :::: .: :..: : . CCDS46 MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFT 10 20 30 40 50 70 80 90 100 110 pF1KSD EWFYRPEGGKDFL-IYEYRNGHQEVESP--FQGRLQWNGS---KDLQDVSITVLNVTLND :: .: .: ..:. : .:.: ..: :.::. :::: :::::.:: . ::: : CCDS46 EWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD SGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLL :: : :.: : . :: .. ..... : ..:... :: CCDS46 SGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDK-GESGAACPFTVTHRRARWRDRWQAV 120 130 140 150 160 170 180 190 200 210 pF1KSD IEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSAVPVEE CCDS46 DRTGWLCAWPANRPQQRAEGEGSSPSCPLQLWPLFLSSPRRGQSMPVPHRRSGYRTQLCH 180 190 200 210 220 230 215 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:11:03 2016 done: Thu Nov 3 05:11:03 2016 Total Scan time: 2.030 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]