Result of FASTA (omim) for
pF1KSDA1171
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1171, 559 aa
1>>>pF1KSDA1171 559 - 559 aa - 559 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3660+/-0.00037; mu= 13.1937+/- 0.023
mean_var=80.5059+/-16.138, 0's: 0 Z-trim(114.8): 136 B-trim: 867 in 1/52
Lambda= 0.142942
statistics sampled from 24744 (24885) to 24744 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.292), width: 16
Scan time: 10.140
The best scores are: opt bits E(85289)
NP_001186036 (OMIM: 613577,614617,616044) TBC1 dom ( 559) 3805 794.5 0
XP_016878982 (OMIM: 613577,614617,616044) PREDICTE ( 559) 3805 794.5 0
XP_016878984 (OMIM: 613577,614617,616044) PREDICTE ( 553) 3752 783.6 0
NP_065756 (OMIM: 613577,614617,616044) TBC1 domain ( 553) 3752 783.6 0
XP_016878983 (OMIM: 613577,614617,616044) PREDICTE ( 553) 3752 783.6 0
XP_011517145 (OMIM: 609871) PREDICTED: TBC1 domain ( 468) 204 51.9 5.4e-06
NP_001254501 (OMIM: 609871) TBC1 domain family mem ( 468) 204 51.9 5.4e-06
XP_016870388 (OMIM: 609871) PREDICTED: TBC1 domain ( 483) 204 51.9 5.5e-06
NP_001254500 (OMIM: 609871) TBC1 domain family mem ( 928) 204 52.0 1e-05
NP_114143 (OMIM: 610020) TBC1 domain family member ( 508) 195 50.0 2.1e-05
NP_001191169 (OMIM: 610020) TBC1 domain family mem ( 515) 195 50.0 2.1e-05
NP_001185464 (OMIM: 605609) oxidation resistance p ( 216) 187 48.3 3e-05
NP_001185463 (OMIM: 605609) oxidation resistance p ( 243) 187 48.3 3.4e-05
NP_056342 (OMIM: 613620) TBC1 domain family member ( 808) 192 49.5 4.9e-05
XP_016869089 (OMIM: 605609) PREDICTED: oxidation r ( 607) 187 48.4 7.7e-05
XP_016869088 (OMIM: 605609) PREDICTED: oxidation r ( 607) 187 48.4 7.7e-05
XP_016869085 (OMIM: 605609) PREDICTED: oxidation r ( 634) 187 48.4 8e-05
XP_016869084 (OMIM: 605609) PREDICTED: oxidation r ( 634) 187 48.4 8e-05
XP_016869087 (OMIM: 605609) PREDICTED: oxidation r ( 634) 187 48.4 8e-05
XP_016869086 (OMIM: 605609) PREDICTED: oxidation r ( 634) 187 48.4 8e-05
XP_016869083 (OMIM: 605609) PREDICTED: oxidation r ( 758) 187 48.4 9.5e-05
XP_016869082 (OMIM: 605609) PREDICTED: oxidation r ( 785) 187 48.4 9.8e-05
XP_016869081 (OMIM: 605609) PREDICTED: oxidation r ( 803) 187 48.4 0.0001
XP_016869080 (OMIM: 605609) PREDICTED: oxidation r ( 804) 187 48.4 0.0001
XP_016869079 (OMIM: 605609) PREDICTED: oxidation r ( 806) 187 48.4 0.0001
XP_011544091 (OMIM: 613620) PREDICTED: TBC1 domain ( 703) 186 48.2 0.0001
NP_851999 (OMIM: 605609) oxidation resistance prot ( 839) 187 48.5 0.0001
NP_060472 (OMIM: 605609) oxidation resistance prot ( 846) 187 48.5 0.0001
XP_006716658 (OMIM: 605609) PREDICTED: oxidation r ( 847) 187 48.5 0.0001
XP_016869078 (OMIM: 605609) PREDICTED: oxidation r ( 866) 187 48.5 0.00011
NP_001185462 (OMIM: 605609) oxidation resistance p ( 873) 187 48.5 0.00011
NP_001185461 (OMIM: 605609) oxidation resistance p ( 874) 187 48.5 0.00011
NP_001186551 (OMIM: 609752) nuclear receptor coact ( 219) 175 45.8 0.00017
XP_006718606 (OMIM: 610831) PREDICTED: carabin iso ( 345) 172 45.2 0.00039
XP_006718604 (OMIM: 610831) PREDICTED: carabin iso ( 345) 172 45.2 0.00039
XP_006718605 (OMIM: 610831) PREDICTED: carabin iso ( 345) 172 45.2 0.00039
XP_011543303 (OMIM: 610831) PREDICTED: carabin iso ( 345) 172 45.2 0.00039
XP_006718607 (OMIM: 610831) PREDICTED: carabin iso ( 345) 172 45.2 0.00039
NP_001186550 (OMIM: 609752) nuclear receptor coact ( 827) 175 46.0 0.00057
XP_006718602 (OMIM: 610831) PREDICTED: carabin iso ( 446) 171 45.1 0.00057
NP_940919 (OMIM: 610831) carabin isoform 1 [Homo s ( 446) 171 45.1 0.00057
XP_006718603 (OMIM: 610831) PREDICTED: carabin iso ( 446) 171 45.1 0.00057
XP_006718601 (OMIM: 610831) PREDICTED: carabin iso ( 446) 171 45.1 0.00057
XP_016865762 (OMIM: 609752) PREDICTED: nuclear rec ( 931) 175 46.0 0.00063
XP_016865763 (OMIM: 609752) PREDICTED: nuclear rec ( 931) 175 46.0 0.00063
XP_016865760 (OMIM: 609752) PREDICTED: nuclear rec ( 931) 175 46.0 0.00063
NP_001116314 (OMIM: 609752) nuclear receptor coact ( 931) 175 46.0 0.00063
XP_016865759 (OMIM: 609752) PREDICTED: nuclear rec ( 931) 175 46.0 0.00063
XP_016865761 (OMIM: 609752) PREDICTED: nuclear rec ( 931) 175 46.0 0.00063
NP_001186548 (OMIM: 609752) nuclear receptor coact ( 942) 175 46.0 0.00064
>>NP_001186036 (OMIM: 613577,614617,616044) TBC1 domain (559 aa)
initn: 3805 init1: 3805 opt: 3805 Z-score: 4240.7 bits: 794.5 E(85289): 0
Smith-Waterman score: 3805; 99.8% identity (100.0% similar) in 559 aa overlap (1-559:1-559)
10 20 30 40 50 60
pF1KSD MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLLSRKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
NP_001 YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLFSRKEI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD QLLQMANEKALKQKGITVKQKSVSLSKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLQMANEKALKQKGITVKQKSVSLSKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD FALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD KLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD PFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCS
490 500 510 520 530 540
550
pF1KSD ENFLIAAVEAWGFQDPDTQ
:::::::::::::::::::
NP_001 ENFLIAAVEAWGFQDPDTQ
550
>>XP_016878982 (OMIM: 613577,614617,616044) PREDICTED: T (559 aa)
initn: 3805 init1: 3805 opt: 3805 Z-score: 4240.7 bits: 794.5 E(85289): 0
Smith-Waterman score: 3805; 99.8% identity (100.0% similar) in 559 aa overlap (1-559:1-559)
10 20 30 40 50 60
pF1KSD MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLLSRKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_016 YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLFSRKEI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD QLLQMANEKALKQKGITVKQKSVSLSKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLQMANEKALKQKGITVKQKSVSLSKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD FALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD KLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD PFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCS
490 500 510 520 530 540
550
pF1KSD ENFLIAAVEAWGFQDPDTQ
:::::::::::::::::::
XP_016 ENFLIAAVEAWGFQDPDTQ
550
>>XP_016878984 (OMIM: 613577,614617,616044) PREDICTED: T (553 aa)
initn: 2150 init1: 2150 opt: 3752 Z-score: 4181.8 bits: 783.6 E(85289): 0
Smith-Waterman score: 3752; 98.7% identity (98.9% similar) in 559 aa overlap (1-559:1-553)
10 20 30 40 50 60
pF1KSD MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLLSRKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_016 YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLFSRKEI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD QLLQMANEKALKQKGITVKQKSVSLSKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPER
::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_016 QLLQMANEKALKQKGITVKQK------RQFVHLAVHAENFRSEIVSVREMRDIWSWVPER
310 320 330 340 350
370 380 390 400 410 420
pF1KSD FALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD KLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD PFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCS
480 490 500 510 520 530
550
pF1KSD ENFLIAAVEAWGFQDPDTQ
:::::::::::::::::::
XP_016 ENFLIAAVEAWGFQDPDTQ
540 550
>>NP_065756 (OMIM: 613577,614617,616044) TBC1 domain fam (553 aa)
initn: 2150 init1: 2150 opt: 3752 Z-score: 4181.8 bits: 783.6 E(85289): 0
Smith-Waterman score: 3752; 98.7% identity (98.9% similar) in 559 aa overlap (1-559:1-553)
10 20 30 40 50 60
pF1KSD MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLLSRKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
NP_065 YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLFSRKEI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD QLLQMANEKALKQKGITVKQKSVSLSKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPER
::::::::::::::::::::: :::::::::::::::::::::::::::::::::
NP_065 QLLQMANEKALKQKGITVKQK------RQFVHLAVHAENFRSEIVSVREMRDIWSWVPER
310 320 330 340 350
370 380 390 400 410 420
pF1KSD FALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD KLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD PFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCS
480 490 500 510 520 530
550
pF1KSD ENFLIAAVEAWGFQDPDTQ
:::::::::::::::::::
NP_065 ENFLIAAVEAWGFQDPDTQ
540 550
>>XP_016878983 (OMIM: 613577,614617,616044) PREDICTED: T (553 aa)
initn: 2150 init1: 2150 opt: 3752 Z-score: 4181.8 bits: 783.6 E(85289): 0
Smith-Waterman score: 3752; 98.7% identity (98.9% similar) in 559 aa overlap (1-559:1-553)
10 20 30 40 50 60
pF1KSD MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQSHALRGKVYQRLIR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACNDPGRRLIDQSFLAFESSC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTFGDLVNKYCQAAHKLMVAVSEDVLQVYADWQRWLFGELPLCYFARVFDVFLVEGYKVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLLSRKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_016 YRVALAILKFFHKVRAGQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLFSRKEI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD QLLQMANEKALKQKGITVKQKSVSLSKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPER
::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_016 QLLQMANEKALKQKGITVKQK------RQFVHLAVHAENFRSEIVSVREMRDIWSWVPER
310 320 330 340 350
370 380 390 400 410 420
pF1KSD FALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLLLIKTTQKEVCGAYLSTDWSERNKFGG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD KLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRLS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD PFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQALYIDGDLNRGRTSHCDTFNNQPLCS
480 490 500 510 520 530
550
pF1KSD ENFLIAAVEAWGFQDPDTQ
:::::::::::::::::::
XP_016 ENFLIAAVEAWGFQDPDTQ
540 550
>>XP_011517145 (OMIM: 609871) PREDICTED: TBC1 domain fam (468 aa)
initn: 127 init1: 100 opt: 204 Z-score: 228.6 bits: 51.9 E(85289): 5.4e-06
Smith-Waterman score: 208; 25.7% identity (54.6% similar) in 339 aa overlap (17-343:147-461)
10 20 30 40
pF1KSD MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQ
::. :: :. ::::: : : .
XP_011 KLLAKIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSA-------ELKQLLRAGV-PR
120 130 140 150 160
50 60 70 80 90 100
pF1KSD SHALRGKVYQRLIRDIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSY--
: : .:.. :.. . :: . :...... ... . . :. : :.
XP_011 EH--RPRVWRWLVHLRVQHLHTP--GCYQELLSRGQAREHPAARQI-ELDLNRTFPNNKH
170 180 190 200 210 220
110 120 130 140 150 160
pF1KSD --CLNARGEGAVRKILLCLANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACN
: .. .:..:: .. : : :..: .: ..:. : .: : :.
XP_011 FTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETI
230 240 250 260 270 280
170 180 190 200 210
pF1KSD DPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSE---DVLQVYADWQRWLFGE
:. . .. : . . .. ::.. . .::. ... :. : .: .:..
XP_011 MPADYYCN-TLTASQVDQRVLQDLLS---EKLPRLMAHLGQHHVDLSLVTFNWFLVVFAD
290 300 310 320 330
220 230 240 250 260 270
pF1KSD -LPLCYFARVFDVFLVEGYKVLYRVALAILKFFHK--VRAGQPLESDSVKQDIRTFVRDI
: . ::.:.:: :: ::..: ::::.:. .: .: . :: . : .: :.. :
XP_011 SLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLE---IYQYLRFFTKTI
340 350 360 370 380 390
280 290 300 310 320 330
pF1KSD AKTVSPEKLLEKAFA-IRLLSRKEIQLLQMANEKALKQKGITVKQ-KSVSLSKRQFVHLA
... .::.. :: . . :... :.:.... :. . ..: :. : .: . :
XP_011 SNS---RKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLKAEYLERRASRRRA
400 410 420 430 440 450
340 350 360 370 380 390
pF1KSD VHAENFRSEIVSVREMRDIWSWVPERFALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLL
: .:. ::
XP_011 V-SEGCASEDEVEGEA
460
>>NP_001254501 (OMIM: 609871) TBC1 domain family member (468 aa)
initn: 127 init1: 100 opt: 204 Z-score: 228.6 bits: 51.9 E(85289): 5.4e-06
Smith-Waterman score: 208; 25.7% identity (54.6% similar) in 339 aa overlap (17-343:147-461)
10 20 30 40
pF1KSD MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQ
::. :: :. ::::: : : .
NP_001 KLLAKIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSA-------ELKQLLRAGV-PR
120 130 140 150 160
50 60 70 80 90 100
pF1KSD SHALRGKVYQRLIRDIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSY--
: : .:.. :.. . :: . :...... ... . . :. : :.
NP_001 EH--RPRVWRWLVHLRVQHLHTP--GCYQELLSRGQAREHPAARQI-ELDLNRTFPNNKH
170 180 190 200 210 220
110 120 130 140 150 160
pF1KSD --CLNARGEGAVRKILLCLANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACN
: .. .:..:: .. : : :..: .: ..:. : .: : :.
NP_001 FTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETI
230 240 250 260 270 280
170 180 190 200 210
pF1KSD DPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSE---DVLQVYADWQRWLFGE
:. . .. : . . .. ::.. . .::. ... :. : .: .:..
NP_001 MPADYYCN-TLTASQVDQRVLQDLLS---EKLPRLMAHLGQHHVDLSLVTFNWFLVVFAD
290 300 310 320 330
220 230 240 250 260 270
pF1KSD -LPLCYFARVFDVFLVEGYKVLYRVALAILKFFHK--VRAGQPLESDSVKQDIRTFVRDI
: . ::.:.:: :: ::..: ::::.:. .: .: . :: . : .: :.. :
NP_001 SLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLE---IYQYLRFFTKTI
340 350 360 370 380 390
280 290 300 310 320 330
pF1KSD AKTVSPEKLLEKAFA-IRLLSRKEIQLLQMANEKALKQKGITVKQ-KSVSLSKRQFVHLA
... .::.. :: . . :... :.:.... :. . ..: :. : .: . :
NP_001 SNS---RKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLKAEYLERRASRRRA
400 410 420 430 440 450
340 350 360 370 380 390
pF1KSD VHAENFRSEIVSVREMRDIWSWVPERFALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLL
: .:. ::
NP_001 V-SEGCASEDEVEGEA
460
>>XP_016870388 (OMIM: 609871) PREDICTED: TBC1 domain fam (483 aa)
initn: 127 init1: 100 opt: 204 Z-score: 228.4 bits: 51.9 E(85289): 5.5e-06
Smith-Waterman score: 208; 25.7% identity (54.6% similar) in 339 aa overlap (17-343:162-476)
10 20 30 40
pF1KSD MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQ
::. :: :. ::::: : : .
XP_016 KLLAKIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSA-------ELKQLLRAGV-PR
140 150 160 170 180
50 60 70 80 90 100
pF1KSD SHALRGKVYQRLIRDIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSY--
: : .:.. :.. . :: . :...... ... . . :. : :.
XP_016 EH--RPRVWRWLVHLRVQHLHTP--GCYQELLSRGQAREHPAARQI-ELDLNRTFPNNKH
190 200 210 220 230
110 120 130 140 150 160
pF1KSD --CLNARGEGAVRKILLCLANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACN
: .. .:..:: .. : : :..: .: ..:. : .: : :.
XP_016 FTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETI
240 250 260 270 280 290
170 180 190 200 210
pF1KSD DPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSE---DVLQVYADWQRWLFGE
:. . .. : . . .. ::.. . .::. ... :. : .: .:..
XP_016 MPADYYCN-TLTASQVDQRVLQDLLS---EKLPRLMAHLGQHHVDLSLVTFNWFLVVFAD
300 310 320 330 340 350
220 230 240 250 260 270
pF1KSD -LPLCYFARVFDVFLVEGYKVLYRVALAILKFFHK--VRAGQPLESDSVKQDIRTFVRDI
: . ::.:.:: :: ::..: ::::.:. .: .: . :: . : .: :.. :
XP_016 SLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLE---IYQYLRFFTKTI
360 370 380 390 400 410
280 290 300 310 320 330
pF1KSD AKTVSPEKLLEKAFA-IRLLSRKEIQLLQMANEKALKQKGITVKQ-KSVSLSKRQFVHLA
... .::.. :: . . :... :.:.... :. . ..: :. : .: . :
XP_016 SNS---RKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLKAEYLERRASRRRA
420 430 440 450 460
340 350 360 370 380 390
pF1KSD VHAENFRSEIVSVREMRDIWSWVPERFALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLL
: .:. ::
XP_016 V-SEGCASEDEVEGEA
470 480
>>NP_001254500 (OMIM: 609871) TBC1 domain family member (928 aa)
initn: 100 init1: 100 opt: 204 Z-score: 223.8 bits: 52.0 E(85289): 1e-05
Smith-Waterman score: 208; 25.7% identity (54.6% similar) in 339 aa overlap (17-343:607-921)
10 20 30 40
pF1KSD MDSPGYNCFVDKDKMDAAIQDLGPKELSCTELQELKQLARQGYWAQ
::. :: :. ::::: : : .
NP_001 KLLAKIQALESRSHHLLGLEAVDRPLRERWAALGDLVPSA-------ELKQLLRAGV-PR
580 590 600 610 620
50 60 70 80 90 100
pF1KSD SHALRGKVYQRLIRDIPCRTVTPDASVYSDIVGKIVGKHSSSCLPLPEFVDNTQVPSY--
: : .:.. :.. . :: . :...... ... . . :. : :.
NP_001 EH--RPRVWRWLVHLRVQHLHTP--GCYQELLSRGQAREHPAARQI-ELDLNRTFPNNKH
630 640 650 660 670 680
110 120 130 140 150 160
pF1KSD --CLNARGEGAVRKILLCLANQFPDISFCPALPAVVALLLHYSIDEAECFEKACRILACN
: .. .:..:: .. : : :..: .: ..:. : .: : :.
NP_001 FTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLEEEESAFWCLVAIVETI
690 700 710 720 730 740
170 180 190 200 210
pF1KSD DPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKLMVAVSE---DVLQVYADWQRWLFGE
:. . .. : . . .. ::.. . .::. ... :. : .: .:..
NP_001 MPADYYCN-TLTASQVDQRVLQDLLS---EKLPRLMAHLGQHHVDLSLVTFNWFLVVFAD
750 760 770 780 790
220 230 240 250 260 270
pF1KSD -LPLCYFARVFDVFLVEGYKVLYRVALAILKFFHK--VRAGQPLESDSVKQDIRTFVRDI
: . ::.:.:: :: ::..: ::::.:. .: .: . :: . : .: :.. :
NP_001 SLISNILLRVWDAFLYEGTKVVFRYALAIFKYNEKEILRLQNGLE---IYQYLRFFTKTI
800 810 820 830 840 850
280 290 300 310 320 330
pF1KSD AKTVSPEKLLEKAFA-IRLLSRKEIQLLQMANEKALKQKGITVKQ-KSVSLSKRQFVHLA
... .::.. :: . . :... :.:.... :. . ..: :. : .: . :
NP_001 SNS---RKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQLKAEYLERRASRRRA
860 870 880 890 900 910
340 350 360 370 380 390
pF1KSD VHAENFRSEIVSVREMRDIWSWVPERFALCQPLLLFSSLQHGYSLARFYFQCEGHEPTLL
: .:. ::
NP_001 V-SEGCASEDEVEGEA
920
>>NP_114143 (OMIM: 610020) TBC1 domain family member 10A (508 aa)
initn: 96 init1: 96 opt: 195 Z-score: 218.0 bits: 50.0 E(85289): 2.1e-05
Smith-Waterman score: 195; 24.0% identity (58.2% similar) in 208 aa overlap (110-314:175-370)
80 90 100 110 120 130
pF1KSD KIVGKHSSSCLPLPEFVDNTQVPSYCLNARGEGAVRKILLCLANQFPDISFCPAL-PAVV
:. . ..: . :. ..: : : ..
NP_114 PGDPKWLDVIERDLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAA
150 160 170 180 190 200
140 150 160 170 180 190
pF1KSD ALLLHYSIDEAE-CFEKACRILACNDPGRRLIDQSFLAFESSCMTFGDLVNKYCQAAHKL
.::.:. ..: :. . :. :: .... :.. . . .:..: .:::
NP_114 VLLMHMPAEQAFWCLVQICEKYL---PGYY--SEKLEAIQLDGEILFSLLQKVSPVAHKH
210 220 230 240 250
200 210 220 230 240 250
pF1KSD MVAVSEDVLQVYADWQRWLFGE-LPLCYFARVFDVFLVEGYKVLYRVALAILKFFHKVRA
. . : : ...: :.. :: ::.:.:. :: :...::.:..:: : .
NP_114 LSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK--HAL--
260 270 280 290 300 310
260 270 280 290 300 310
pF1KSD GQPLESDSVKQDIRTFVRDIAKTVSPEKLLEKAFAIRLLSRKEIQLLQMANEKALKQKGI
:.: . . . . .:. : ...:: :....:: .. . . . :. :. .. .
NP_114 GSPEKVKACQGQYETIER--LRSLSP-KIMQEAFLVQEVVELPVTERQIEREHLIQLRRW
320 330 340 350 360 370
320 330 340 350 360 370
pF1KSD TVKQKSVSLSKRQFVHLAVHAENFRSEIVSVREMRDIWSWVPERFALCQPLLLFSSLQHG
NP_114 QETRGELQCRSPPRLHGAKAILDAEPGPRPALQPSPSIRLPLDAPLPGSKAKPKPPKQAQ
380 390 400 410 420 430
559 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:12:58 2016 done: Thu Nov 3 05:13:00 2016
Total Scan time: 10.140 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]