FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1184, 385 aa 1>>>pF1KSDA1184 385 - 385 aa - 385 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5585+/-0.000624; mu= 15.9568+/- 0.038 mean_var=67.0140+/-13.341, 0's: 0 Z-trim(111.3): 12 B-trim: 0 in 0/51 Lambda= 0.156672 statistics sampled from 12287 (12298) to 12287 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.378), width: 16 Scan time: 3.000 The best scores are: opt bits E(32554) CCDS2411.1 PNKD gene_id:25953|Hs108|chr2 ( 385) 2625 601.7 3.7e-172 CCDS2413.1 PNKD gene_id:25953|Hs108|chr2 ( 361) 2114 486.1 2.1e-137 CCDS32366.1 HAGH gene_id:3029|Hs108|chr16 ( 260) 647 154.5 1e-37 CCDS10447.2 HAGH gene_id:3029|Hs108|chr16 ( 308) 647 154.5 1.2e-37 CCDS32354.1 HAGHL gene_id:84264|Hs108|chr16 ( 282) 585 140.5 1.8e-33 CCDS42816.1 PNKD gene_id:25953|Hs108|chr2 ( 142) 519 125.5 3.1e-29 CCDS12622.1 ETHE1 gene_id:23474|Hs108|chr19 ( 254) 278 71.1 1.3e-12 CCDS66900.1 HAGH gene_id:3029|Hs108|chr16 ( 236) 274 70.2 2.2e-12 >>CCDS2411.1 PNKD gene_id:25953|Hs108|chr2 (385 aa) initn: 2625 init1: 2625 opt: 2625 Z-score: 3204.3 bits: 601.7 E(32554): 3.7e-172 Smith-Waterman score: 2625; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385) 10 20 30 40 50 60 pF1KSD MAAVVAATALKGRGARNARVLRGILAGATANKASHNRTRALQSHSSPEGKEEPEPLSPEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 MAAVVAATALKGRGARNARVLRGILAGATANKASHNRTRALQSHSSPEGKEEPEPLSPEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EYIPRKRGKNPMKAVGLAWYSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 EYIPRKRGKNPMKAVGLAWYSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD VLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAILCTHKHWDHSGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 VLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAILCTHKHWDHSGG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 NRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD EPYKGPSCLFSGDLLFLSGCGRTFEGNAETMLSSLDTVLGLGDDTLLWPGHEYAEENLGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 EPYKGPSCLFSGDLLFLSGCGRTFEGNAETMLSSLDTVLGLGDDTLLWPGHEYAEENLGF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AGVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLALQEALGPGPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 AGVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLALQEALGPGPGP 310 320 330 340 350 360 370 380 pF1KSD TGDDDYSRAQLLEELRRLKDMHKSK ::::::::::::::::::::::::: CCDS24 TGDDDYSRAQLLEELRRLKDMHKSK 370 380 >>CCDS2413.1 PNKD gene_id:25953|Hs108|chr2 (361 aa) initn: 2148 init1: 2114 opt: 2114 Z-score: 2580.5 bits: 486.1 E(32554): 2.1e-137 Smith-Waterman score: 2114; 100.0% identity (100.0% similar) in 306 aa overlap (80-385:56-361) 50 60 70 80 90 100 pF1KSD KEEPEPLSPELEYIPRKRGKNPMKAVGLAWYSLYTRTWLGYLFYRQQLRRARNRYPKGHS :::::::::::::::::::::::::::::: CCDS24 LLVSPRGCRARRGLRGLLMAHSQRLLFRIGYSLYTRTWLGYLFYRQQLRRARNRYPKGHS 30 40 50 60 70 80 110 120 130 140 150 160 pF1KSD KTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 KTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAIL 90 100 110 120 130 140 170 180 190 200 210 220 pF1KSD CTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 CTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGH 150 160 170 180 190 200 230 240 250 260 270 280 pF1KSD TQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGNAETMLSSLDTVLGLGDDTLLWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 TQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGNAETMLSSLDTVLGLGDDTLLWP 210 220 230 240 250 260 290 300 310 320 330 340 pF1KSD GHEYAEENLGFAGVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 GHEYAEENLGFAGVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLA 270 280 290 300 310 320 350 360 370 380 pF1KSD LQEALGPGPGPTGDDDYSRAQLLEELRRLKDMHKSK :::::::::::::::::::::::::::::::::::: CCDS24 LQEALGPGPGPTGDDDYSRAQLLEELRRLKDMHKSK 330 340 350 360 >>CCDS32366.1 HAGH gene_id:3029|Hs108|chr16 (260 aa) initn: 550 init1: 324 opt: 647 Z-score: 790.7 bits: 154.5 E(32554): 1e-37 Smith-Waterman score: 648; 40.6% identity (69.2% similar) in 266 aa overlap (119-383:1-256) 90 100 110 120 130 140 pF1KSD GYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDP .:: .:.:.::: ::.:: ... :. ::: CCDS32 MKVEVLPALTDNYMYLVIDDETKEAAIVDP 10 20 30 150 160 170 180 190 200 pF1KSD SDPRAVQASIEKEGVTLVAILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPL .:. : . .:.:: :...: ::.::::.:::. : . . .:::. .: : ::: . CCDS32 VQPQKVVDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLESGLKVYGG-DDRIGALTHKI 40 50 60 70 80 210 220 230 240 250 260 pF1KSD CHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGNA : ....:: :... :::: ::.::. :... . : .:.:: ::..:::. .::.: CCDS32 THLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGDTLFVAGCGKFYEGTA 90 100 110 120 130 140 270 280 290 300 310 320 pF1KSD ETMLSSLDTVLG-LGDDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQRQRLERKG . : ..: ::: : :: .. ::::. .:: :: ::: : : ..:. :.... . CCDS32 DEMCKALLEVLGRLPPDTRVYCGHEYTINNLKFARHVEPGNAAIREKLAWAKEKYSIGEP 150 160 170 180 190 200 330 340 350 360 370 380 pF1KSD TCPSTLGEERSYNPFLRTHCLALQEALGPGPGPTGDDDYSRAQLLEELRRLKDMHKSK : ::::.:: .::::.:.. ..:. .:. : . .. .:: ::. : CCDS32 TVPSTLAEEFTYNPFMRVREKTVQQH-------AGETDP--VTTMRAVRREKDQFKMPRD 210 220 230 240 250 260 >>CCDS10447.2 HAGH gene_id:3029|Hs108|chr16 (308 aa) initn: 550 init1: 324 opt: 647 Z-score: 789.5 bits: 154.5 E(32554): 1.2e-37 Smith-Waterman score: 648; 40.6% identity (69.2% similar) in 266 aa overlap (119-383:49-304) 90 100 110 120 130 140 pF1KSD GYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDP .:: .:.:.::: ::.:: ... :. ::: CCDS10 ACARRGLGPALLGVFCHTDLRKNLTVDEGTMKVEVLPALTDNYMYLVIDDETKEAAIVDP 20 30 40 50 60 70 150 160 170 180 190 200 pF1KSD SDPRAVQASIEKEGVTLVAILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPL .:. : . .:.:: :...: ::.::::.:::. : . . .:::. .: : ::: . CCDS10 VQPQKVVDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLESGLKVYGG-DDRIGALTHKI 80 90 100 110 120 130 210 220 230 240 250 260 pF1KSD CHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGNA : ....:: :... :::: ::.::. :... . : .:.:: ::..:::. .::.: CCDS10 THLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGDTLFVAGCGKFYEGTA 140 150 160 170 180 190 270 280 290 300 310 320 pF1KSD ETMLSSLDTVLG-LGDDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQRQRLERKG . : ..: ::: : :: .. ::::. .:: :: ::: : : ..:. :.... . CCDS10 DEMCKALLEVLGRLPPDTRVYCGHEYTINNLKFARHVEPGNAAIREKLAWAKEKYSIGEP 200 210 220 230 240 250 330 340 350 360 370 380 pF1KSD TCPSTLGEERSYNPFLRTHCLALQEALGPGPGPTGDDDYSRAQLLEELRRLKDMHKSK : ::::.:: .::::.:.. ..:. .:. : . .. .:: ::. : CCDS10 TVPSTLAEEFTYNPFMRVREKTVQQH-------AGETDP--VTTMRAVRREKDQFKMPRD 260 270 280 290 300 >>CCDS32354.1 HAGHL gene_id:84264|Hs108|chr16 (282 aa) initn: 582 init1: 373 opt: 585 Z-score: 714.4 bits: 140.5 E(32554): 1.8e-33 Smith-Waterman score: 585; 43.8% identity (65.9% similar) in 226 aa overlap (119-344:1-225) 90 100 110 120 130 140 pF1KSD GYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDP .:: :::: ::: ::.:. .. ::::: CCDS32 MKVKVIPVLEDNYMYLVIEELTREAVAVDV 10 20 30 150 160 170 180 190 200 pF1KSD SDPRAVQASIEKEGVTLVAILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPL . :. . . .:::.:.:.: ::.::::. :: .:.: . : :. .. : ::. : CCDS32 AVPKRLLEIVGREGVSLTAVLTTHHHWDHARGNPELARLRPGLAVLGA-DERIFSLTRRL 40 50 60 70 80 210 220 230 240 250 260 pF1KSD CHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGNA : . . : ...: : ::::: ::. :.: . : ::::: : ..::: .::.: CCDS32 AHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDDCPDPPALFSGDALSVAGCGSCLEGSA 90 100 110 120 130 140 270 280 290 300 310 320 pF1KSD ETMLSSLDTVLGLGDDTLLWPGHEYAEENLGFAGVVEPENLARERKMQWVQRQRLERKGT . : .:: . : .: .. :::.. :: :: ::: : . :..:.... . : CCDS32 QQMYQSLAELGTLPPETKVFCGHEHTLSNLEFAQKVEPCNDHVRAKLSWAKKRDEDDVPT 150 160 170 180 190 200 330 340 350 360 370 380 pF1KSD CPSTLGEERSYNPFLRTHCLALQEALGPGPGPTGDDDYSRAQLLEELRRLKDMHKSK :::::::: :::::: CCDS32 VPSTLGEERLYNPFLRVAEEPVRKFTGKAVPADVLEALCKERARFEQAGEPRQPQARALL 210 220 230 240 250 260 >>CCDS42816.1 PNKD gene_id:25953|Hs108|chr2 (142 aa) initn: 511 init1: 511 opt: 519 Z-score: 638.4 bits: 125.5 E(32554): 3.1e-29 Smith-Waterman score: 519; 72.6% identity (83.8% similar) in 117 aa overlap (1-117:1-115) 10 20 30 40 50 60 pF1KSD MAAVVAATALKGRGARNARVLRGILAGATANKASHNRTRALQSHSSPEGKEEPEPLSPEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MAAVVAATALKGRGARNARVLRGILAGATANKASHNRTRALQSHSSPEGKEEPEPLSPEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EYIPRKRGKNPMKAVGLAWYSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVK ::::::::::::::::::: . : ... .... . : . : .. . :: : CCDS42 EYIPRKRGKNPMKAVGLAWAIGFPCGILLFILTKREVDKDRVKQMK--ARQNMRLSNTGE 70 80 90 100 110 130 140 150 160 170 180 pF1KSD VLPIPVLSDNYSYLIIDTQAQLAVAVDPSDPRAVQASIEKEGVTLVAILCTHKHWDHSGG CCDS42 YESQRFRASSQSAPSPDVGSGVQT 120 130 140 >>CCDS12622.1 ETHE1 gene_id:23474|Hs108|chr19 (254 aa) initn: 297 init1: 73 opt: 278 Z-score: 340.1 bits: 71.1 E(32554): 1.3e-12 Smith-Waterman score: 278; 31.2% identity (55.8% similar) in 224 aa overlap (97-313:6-214) 70 80 90 100 110 120 pF1KSD RGKNPMKAVGLAWYSLYTRTWLGYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPV :: :: . . .. : :. . . :: CCDS12 MAEAVLRVARRQLSQRGGSGAPILL---RQMFEPV 10 20 30 130 140 150 160 170 180 pF1KSD LSDNYSYLIIDTQAQLAVAVDP---SDPRAVQASIEKEGVTLVAILCTHKHWDHSGGNRD : ...::. : ... :: .:: . :: .: :.. :. :. . :: : :: :. CCDS12 -SCTFTYLLGDRESREAVLIDPVLETAPRDAQL-IKELGLRLLYAVNTHCHADHITGSGL 40 50 60 70 80 90 190 200 210 220 230 240 pF1KSD LSRRHRDCRVYGSPQDGIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPY : :. : .: : . : . ::. ... :.:::: : ....:. . CCDS12 LRSLLPGCQSVISRLSGAQADLH-IEDGDSIRFGRFALETRASPGHTPGCVTFVLNDH-- 100 110 120 130 140 250 260 270 280 290 300 pF1KSD KGPSCLFSGDLLFLSGCGRT-FE-GNAETMLSSL-DTVLGLGDDTLLWPGHEYAEENLGF : :.:: :.. ::::: :. : :.:. :. . .. : : :..:.:.: :: CCDS12 ---SMAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYH----GF 150 160 170 180 190 200 310 320 330 340 350 pF1KSD A-GVVEPENLARERKMQWVQRQRLERKGTCPSTLGEERSYNPFLRTHCLALQEALGPGPG . ..:: : : CCDS12 TVSTVEEERTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFAVPANMRCGVQTPTA 210 220 230 240 250 >>CCDS66900.1 HAGH gene_id:3029|Hs108|chr16 (236 aa) initn: 265 init1: 246 opt: 274 Z-score: 335.7 bits: 70.2 E(32554): 2.2e-12 Smith-Waterman score: 274; 42.9% identity (73.5% similar) in 98 aa overlap (119-216:49-145) 90 100 110 120 130 140 pF1KSD GYLFYRQQLRRARNRYPKGHSKTQPRLFNGVKVLPIPVLSDNYSYLIIDTQAQLAVAVDP .:: .:.:.::: ::.:: ... :. ::: CCDS66 ACARRGLGPALLGVFCHTDLRKNLTVDEGTMKVEVLPALTDNYMYLVIDDETKEAAIVDP 20 30 40 50 60 70 150 160 170 180 190 200 pF1KSD SDPRAVQASIEKEGVTLVAILCTHKHWDHSGGNRDLSRRHRDCRVYGSPQDGIPYLTHPL .:. : . .:.:: :...: ::.::::.:::. : . . .:::. .: : ::: . CCDS66 VQPQKVVDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLESGLKVYGG-DDRIGALTHKI 80 90 100 110 120 130 210 220 230 240 250 260 pF1KSD CHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRTFEGNA : ....: CCDS66 THLSTLQVTPCLWLAAGSSMKGLRMRCVKLCWRSWAGSPRTQESTVATSTPSTTSSLHAT 140 150 160 170 180 190 385 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:13:34 2016 done: Thu Nov 3 05:13:35 2016 Total Scan time: 3.000 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]