FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1186, 403 aa 1>>>pF1KSDA1186 403 - 403 aa - 403 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4537+/-0.000367; mu= 15.9623+/- 0.023 mean_var=66.7893+/-13.412, 0's: 0 Z-trim(113.3): 45 B-trim: 267 in 1/51 Lambda= 0.156935 statistics sampled from 22516 (22561) to 22516 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.265), width: 16 Scan time: 8.550 The best scores are: opt bits E(85289) NP_036561 (OMIM: 607558) SEC14-like protein 2 isof ( 403) 2761 634.2 1.7e-181 NP_203740 (OMIM: 607558) SEC14-like protein 2 isof ( 392) 2485 571.7 1.1e-162 NP_001278861 (OMIM: 607558) SEC14-like protein 2 i ( 349) 2398 551.9 8.5e-157 NP_777635 (OMIM: 612824) SEC14-like protein 3 isof ( 400) 2224 512.6 6.9e-145 NP_777637 (OMIM: 612825) SEC14-like protein 4 isof ( 406) 2063 476.1 6.6e-134 XP_011528430 (OMIM: 612824) PREDICTED: SEC14-like ( 412) 2060 475.4 1.1e-133 XP_016884276 (OMIM: 612825) PREDICTED: SEC14-like ( 465) 1982 457.8 2.4e-128 NP_001154840 (OMIM: 612825) SEC14-like protein 4 i ( 360) 1870 432.4 8.4e-121 NP_001244311 (OMIM: 612824) SEC14-like protein 3 i ( 341) 1858 429.7 5.3e-120 NP_001244308 (OMIM: 612824) SEC14-like protein 3 i ( 341) 1858 429.7 5.3e-120 NP_001191133 (OMIM: 607558) SEC14-like protein 2 i ( 320) 1801 416.8 3.9e-116 XP_016884278 (OMIM: 612825) PREDICTED: SEC14-like ( 352) 1757 406.8 4.2e-113 XP_006724298 (OMIM: 612825) PREDICTED: SEC14-like ( 352) 1757 406.8 4.2e-113 XP_016884280 (OMIM: 612825) PREDICTED: SEC14-like ( 352) 1757 406.8 4.2e-113 NP_001244307 (OMIM: 612824) SEC14-like protein 3 i ( 323) 1756 406.6 4.5e-113 XP_011528466 (OMIM: 612825) PREDICTED: SEC14-like ( 391) 1735 401.9 1.4e-111 XP_016884277 (OMIM: 612825) PREDICTED: SEC14-like ( 437) 949 223.9 5.9e-58 XP_016884279 (OMIM: 612825) PREDICTED: SEC14-like ( 247) 825 195.7 1e-49 NP_001137473 (OMIM: 601504) SEC14-like protein 1 i ( 681) 633 152.5 3e-36 NP_002994 (OMIM: 601504) SEC14-like protein 1 isof ( 715) 633 152.5 3.1e-36 NP_001137471 (OMIM: 601504) SEC14-like protein 1 i ( 715) 633 152.5 3.1e-36 NP_001137470 (OMIM: 601504) SEC14-like protein 1 i ( 715) 633 152.5 3.1e-36 NP_001191339 (OMIM: 601504) SEC14-like protein 1 i ( 715) 633 152.5 3.1e-36 NP_001034662 (OMIM: 601504) SEC14-like protein 1 i ( 719) 633 152.5 3.1e-36 NP_001191337 (OMIM: 601504) SEC14-like protein 1 i ( 719) 633 152.5 3.1e-36 NP_000361 (OMIM: 277460,600415) alpha-tocopherol t ( 278) 238 62.8 1.2e-09 NP_001010852 (OMIM: 616945) clavesin-2 [Homo sapie ( 327) 229 60.8 5.4e-09 XP_016865755 (OMIM: 616945) PREDICTED: clavesin-2 ( 327) 229 60.8 5.4e-09 NP_775790 (OMIM: 611292) clavesin-1 [Homo sapiens] ( 354) 217 58.1 3.8e-08 XP_016868631 (OMIM: 611292) PREDICTED: clavesin-1 ( 354) 217 58.1 3.8e-08 XP_016868630 (OMIM: 611292) PREDICTED: clavesin-1 ( 354) 217 58.1 3.8e-08 XP_006716531 (OMIM: 277460,600415) PREDICTED: alph ( 162) 181 49.8 5.6e-06 NP_000317 (OMIM: 136880,180090,607475,607476) reti ( 317) 150 43.0 0.0013 XP_011520172 (OMIM: 136880,180090,607475,607476) P ( 317) 150 43.0 0.0013 XP_016877949 (OMIM: 136880,180090,607475,607476) P ( 326) 150 43.0 0.0013 XP_006713397 (OMIM: 607182,610019) PREDICTED: FYVE (1478) 157 44.9 0.0016 XP_006713396 (OMIM: 607182,610019) PREDICTED: FYVE (1478) 157 44.9 0.0016 XP_011532413 (OMIM: 607182,610019) PREDICTED: FYVE (1478) 157 44.9 0.0016 NP_078789 (OMIM: 607182,610019) FYVE and coiled-co (1478) 157 44.9 0.0016 >>NP_036561 (OMIM: 607558) SEC14-like protein 2 isoform (403 aa) initn: 2761 init1: 2761 opt: 2761 Z-score: 3379.2 bits: 634.2 E(85289): 1.7e-181 Smith-Waterman score: 2761; 100.0% identity (100.0% similar) in 403 aa overlap (1-403:1-403) 10 20 30 40 50 60 pF1KSD MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 NYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CVLRWQFMSDGADVGFGIFLKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 CVLRWQFMSDGADVGFGIFLKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGI 310 320 330 340 350 360 370 380 390 400 pF1KSD YVLRFDNTYSFIHAKKVNFTVEVLLPDKASEEKMKQLGAGTPK ::::::::::::::::::::::::::::::::::::::::::: NP_036 YVLRFDNTYSFIHAKKVNFTVEVLLPDKASEEKMKQLGAGTPK 370 380 390 400 >>NP_203740 (OMIM: 607558) SEC14-like protein 2 isoform (392 aa) initn: 2485 init1: 2485 opt: 2485 Z-score: 3041.7 bits: 571.7 E(85289): 1.1e-162 Smith-Waterman score: 2485; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360) 10 20 30 40 50 60 pF1KSD MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 EFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 NYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CVLRWQFMSDGADVGFGIFLKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 CVLRWQFMSDGADVGFGIFLKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGI 310 320 330 340 350 360 370 380 390 400 pF1KSD YVLRFDNTYSFIHAKKVNFTVEVLLPDKASEEKMKQLGAGTPK NP_203 CKYLCLGNALKPHVQLSACEVPLPPWIFGSEC 370 380 390 >>NP_001278861 (OMIM: 607558) SEC14-like protein 2 isofo (349 aa) initn: 2398 init1: 2398 opt: 2398 Z-score: 2936.0 bits: 551.9 E(85289): 8.5e-157 Smith-Waterman score: 2398; 100.0% identity (100.0% similar) in 349 aa overlap (55-403:1-349) 30 40 50 60 70 80 pF1KSD DVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDNIISWQPPEVIQQYL :::::::::::::::::::::::::::::: NP_001 MLRKHVEFRKQKDIDNIISWQPPEVIQQYL 10 20 30 90 100 110 120 130 140 pF1KSD SGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGR 40 50 60 70 80 90 150 160 170 180 190 200 pF1KSD KVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KSD IKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVEYGGTMTDPDGNPKCKSKINYGGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVEYGGTMTDPDGNPKCKSKINYGGDI 160 170 180 190 200 210 270 280 290 300 310 320 pF1KSD PRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPGCVLRWQFMSDGADVGFGIFLKTKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPGCVLRWQFMSDGADVGFGIFLKTKM 220 230 240 250 260 270 330 340 350 360 370 380 pF1KSD GERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNTYSFIHAKKVNFTVEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNTYSFIHAKKVNFTVEVL 280 290 300 310 320 330 390 400 pF1KSD LPDKASEEKMKQLGAGTPK ::::::::::::::::::: NP_001 LPDKASEEKMKQLGAGTPK 340 >>NP_777635 (OMIM: 612824) SEC14-like protein 3 isoform (400 aa) initn: 2217 init1: 2217 opt: 2224 Z-score: 2722.2 bits: 512.6 E(85289): 6.9e-145 Smith-Waterman score: 2224; 77.3% identity (93.7% similar) in 397 aa overlap (1-397:1-397) 10 20 30 40 50 60 pF1KSD MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHV ::::::::::.: :.::::::::::::::::::::::::::::::.::::::::.:::.. NP_777 MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKYM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL :::: :::.:..::::::::.:. ::.:::: :::::::::::::: ::::::..:::: NP_777 EFRKTMDIDHILDWQPPEVIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEE :.::::.:: .:.:: :: .::.:.:::..:.:::::::::.::: ::.: ::. ..:: NP_777 LKTKMRDCERILHECDLQTERLGKKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE ::::::: ...::: :::::.:::.:::::::::.::.::: :::: ::: :::...:.. NP_777 NYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLGNNWKEGLLKLISPEELPAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPG .:::.::::::::: .::::::.::...::::::: ::::::::.::::::::::::::: NP_777 FGGTLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQINRGSSHQVEYEILFPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CVLRWQFMSDGADVGFGIFLKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGI ::::::: :::::.:::.::::::::::::::::.:::.::::.:.:::::.::::. :. NP_777 CVLRWQFSSDGADIGFGVFLKTKMGERQRAGEMTDVLPSQRYNAHMVPEDGNLTCSEAGV 310 320 330 340 350 360 370 380 390 400 pF1KSD YVLRFDNTYSFIHAKKVNFTVEVLLPDKASEEKMKQLGAGTPK :::::::::::.:::::.:::::::::.. .. :.: NP_777 YVLRFDNTYSFVHAKKVSFTVEVLLPDEGMQKYDKELTPV 370 380 390 400 >>NP_777637 (OMIM: 612825) SEC14-like protein 4 isoform (406 aa) initn: 2084 init1: 2063 opt: 2063 Z-score: 2525.1 bits: 476.1 E(85289): 6.6e-134 Smith-Waterman score: 2063; 70.4% identity (89.6% similar) in 402 aa overlap (1-402:1-402) 10 20 30 40 50 60 pF1KSD MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHV ::.:::::::.:.::::.::::.::.:: ::: ::::::::::::.::::::: :::.:. NP_777 MSSRVGDLSPQQQEALARFRENLQDLLPILPNADDYFLLRWLRARNFDLQKSEDMLRRHM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL :::::.:.:::..:::::::: : :::.:::: .::::...::: :: ::::.::::::. NP_777 EFRKQQDLDNIVTWQPPEVIQLYDSGGLCGYDYEGCPVYFNIIGSLDPKGLLLSASKQDM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEE .: ... :::::.:: :: :::::.: ...: :::.::::::::::.: .:. ..: NP_777 IRKRIKVCELLLHECELQTQKLGRKIEMALMVFDMEGLSLKHLWKPAVEVYQQFFSILEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE ::::::: :.:..::::::::.::.: :.::.::.::..:: :::. : : :::::.::: NP_777 NYPETLKNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVILGDNWKQELTKFISPDQLPVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPG .::::::::::::: .::::::..:..::. .::. ::::. ...:::: ::: :::::: NP_777 FGGTMTDPDGNPKCLTKINYGGEVPKSYYLCEQVRLQYEHTRSVGRGSSLQVENEILFPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CVLRWQFMSDGADVGFGIFLKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGI ::::::: :::.:.:::.::::::::.: : :::::::.::::.:.:::::.::: . :. NP_777 CVLRWQFASDGGDIGFGVFLKTKMGEQQSAREMTEVLPSQRYNAHMVPEDGSLTCLQAGV 310 320 330 340 350 360 370 380 390 400 pF1KSD YVLRFDNTYSFIHAKKVNFTVEVLLPDKASEEKMKQLGAGTPK :::::::::: .::::...::::::::::::: ...: : : NP_777 YVLRFDNTYSRMHAKKLSYTVEVLLPDKASEETLQSLKAMRPSPTQ 370 380 390 400 >>XP_011528430 (OMIM: 612824) PREDICTED: SEC14-like prot (412 aa) initn: 2060 init1: 2060 opt: 2060 Z-score: 2521.3 bits: 475.4 E(85289): 1.1e-133 Smith-Waterman score: 2060; 77.9% identity (93.9% similar) in 362 aa overlap (1-362:1-362) 10 20 30 40 50 60 pF1KSD MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHV ::::::::::.: :.::::::::::::::::::::::::::::::.::::::::.:::.. XP_011 MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKYM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL :::: :::.:..::::::::.:. ::.:::: :::::::::::::: ::::::..:::: XP_011 EFRKTMDIDHILDWQPPEVIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEE :.::::.:: .:.:: :: .::.:.:::..:.:::::::::.::: ::.: ::. ..:: XP_011 LKTKMRDCERILHECDLQTERLGKKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE ::::::: ...::: :::::.:::.:::::::::.::.::: :::: ::: :::...:.. XP_011 NYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLGNNWKEGLLKLISPEELPAQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPG .:::.::::::::: .::::::.::...::::::: ::::::::.::::::::::::::: XP_011 FGGTLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQINRGSSHQVEYEILFPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CVLRWQFMSDGADVGFGIFLKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGI ::::::: :::::.:::.::::::::::::::::.:::.::::.:.:::::.::::. :. XP_011 CVLRWQFSSDGADIGFGVFLKTKMGERQRAGEMTDVLPSQRYNAHMVPEDGNLTCSEAGV 310 320 330 340 350 360 370 380 390 400 pF1KSD YVLRFDNTYSFIHAKKVNFTVEVLLPDKASEEKMKQLGAGTPK :: XP_011 YVESESGKSCCHLPVIICSHELQNSHSNSQVMAYQMVRKCKLSRPLPLPASN 370 380 390 400 410 >>XP_016884276 (OMIM: 612825) PREDICTED: SEC14-like prot (465 aa) initn: 1991 init1: 1969 opt: 1982 Z-score: 2425.1 bits: 457.8 E(85289): 2.4e-128 Smith-Waterman score: 1982; 69.0% identity (88.3% similar) in 393 aa overlap (10-402:69-461) 10 20 30 pF1KSD MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLL : . . :.::::.::.:: ::: :::::: XP_016 PAWSSGGVDWWMMWEGLGAGLVAPEVMRAPPTIRSSSAQFRENLQDLLPILPNADDYFLL 40 50 60 70 80 90 40 50 60 70 80 90 pF1KSD RWLRARSFDLQKSEAMLRKHVEFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVW ::::::.::::::: :::.:.:::::.:.:::..:::::::: : :::.:::: .::::. XP_016 RWLRARNFDLQKSEDMLRRHMEFRKQQDLDNIVTWQPPEVIQLYDSGGLCGYDYEGCPVY 100 110 120 130 140 150 100 110 120 130 140 150 pF1KSD YDIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLG ..::: :: ::::.::::::..: ... :::::.:: :: :::::.: ...: :::. XP_016 FNIIGSLDPKGLLLSASKQDMIRKRIKVCELLLHECELQTQKLGRKIEMALMVFDMEGLS 160 170 180 190 200 210 160 170 180 190 200 210 pF1KSD LKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMV ::::::::::.: .:. ..: ::::::: :.:..::::::::.::.: :.::.::.::.. XP_016 LKHLWKPAVEVYQQFFSILEANYPETLKNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVI 220 230 240 250 260 270 220 230 240 250 260 270 pF1KSD LGANWKEVLLKHISPDQVPVEYGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYE :: :::. : : :::::.:::.::::::::::::: .::::::..:..::. .::. ::: XP_016 LGDNWKQELTKFISPDQLPVEFGGTMTDPDGNPKCLTKINYGGEVPKSYYLCEQVRLQYE 280 290 300 310 320 330 280 290 300 310 320 330 pF1KSD HSVQISRGSSHQVEYEILFPGCVLRWQFMSDGADVGFGIFLKTKMGERQRAGEMTEVLPN :. ...:::: ::: ::::::::::::: :::.:.:::.::::::::.: : :::::::. XP_016 HTRSVGRGSSLQVENEILFPGCVLRWQFASDGGDIGFGVFLKTKMGEQQSAREMTEVLPS 340 350 360 370 380 390 340 350 360 370 380 390 pF1KSD QRYNSHLVPEDGTLTCSDPGIYVLRFDNTYSFIHAKKVNFTVEVLLPDKASEEKMKQLGA ::::.:.:::::.::: . :.:::::::::: .::::...::::::::::::: ...: : XP_016 QRYNAHMVPEDGSLTCLQAGVYVLRFDNTYSRMHAKKLSYTVEVLLPDKASEETLQSLKA 400 410 420 430 440 450 400 pF1KSD GTPK : XP_016 MRPSPTQ 460 >>NP_001154840 (OMIM: 612825) SEC14-like protein 4 isofo (360 aa) initn: 1891 init1: 1870 opt: 1870 Z-score: 2289.7 bits: 432.4 E(85289): 8.4e-121 Smith-Waterman score: 1870; 70.3% identity (89.7% similar) in 360 aa overlap (1-360:1-360) 10 20 30 40 50 60 pF1KSD MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHV ::.:::::::.:.::::.::::.::.:: ::: ::::::::::::.::::::: :::.:. NP_001 MSSRVGDLSPQQQEALARFRENLQDLLPILPNADDYFLLRWLRARNFDLQKSEDMLRRHM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EFRKQKDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDL :::::.:.:::..:::::::: : :::.:::: .::::...::: :: ::::.::::::. NP_001 EFRKQQDLDNIVTWQPPEVIQLYDSGGLCGYDYEGCPVYFNIIGSLDPKGLLLSASKQDM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LRTKMRECELLLQECAHQTTKLGRKVETITIIYDCEGLGLKHLWKPAVEAYGEFLCMFEE .: ... :::::.:: :: :::::.: ...: :::.::::::::::.: .:. ..: NP_001 IRKRIKVCELLLHECELQTQKLGRKIEMALMVFDMEGLSLKHLWKPAVEVYQQFFSILEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRKKIMVLGANWKEVLLKHISPDQVPVE ::::::: :.:..::::::::.::.: :.::.::.::..:: :::. : : :::::.::: NP_001 NYPETLKNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVILGDNWKQELTKFISPDQLPVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD YGGTMTDPDGNPKCKSKINYGGDIPRKYYVRDQVKQQYEHSVQISRGSSHQVEYEILFPG .::::::::::::: .::::::..:..::. .::. ::::. ...:::: ::: :::::: NP_001 FGGTMTDPDGNPKCLTKINYGGEVPKSYYLCEQVRLQYEHTRSVGRGSSLQVENEILFPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CVLRWQFMSDGADVGFGIFLKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGI ::::::: :::.:.:::.::::::::.: : :::::::.::::.:.:::::.::: . :. NP_001 CVLRWQFASDGGDIGFGVFLKTKMGEQQSAREMTEVLPSQRYNAHMVPEDGSLTCLQAGV 310 320 330 340 350 360 370 380 390 400 pF1KSD YVLRFDNTYSFIHAKKVNFTVEVLLPDKASEEKMKQLGAGTPK >>NP_001244311 (OMIM: 612824) SEC14-like protein 3 isofo (341 aa) initn: 1850 init1: 1850 opt: 1858 Z-score: 2275.4 bits: 429.7 E(85289): 5.3e-120 Smith-Waterman score: 1858; 75.1% identity (92.9% similar) in 338 aa overlap (60-397:1-338) 30 40 50 60 70 80 pF1KSD LPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDNIISWQPPEVIQQYLSGGMC .:::: :::.:..::::::::.:. ::.: NP_001 MEFRKTMDIDHILDWQPPEVIQKYMPGGLC 10 20 30 90 100 110 120 130 140 pF1KSD GYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETI ::: :::::::::::::: ::::::..:::::.::::.:: .:.:: :: .::.:.::: NP_001 GYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERILHECDLQTERLGKKIETI 40 50 60 70 80 90 150 160 170 180 190 200 pF1KSD TIIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFL ..:.:::::::::.::: ::.: ::. ..::::::::: ...::: :::::.:::.:::: NP_001 VMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KSD SEDTRKKIMVLGANWKEVLLKHISPDQVPVEYGGTMTDPDGNPKCKSKINYGGDIPRKYY :::::.::.::: :::: ::: :::...:...:::.::::::::: .::::::.::...: NP_001 SEDTRRKIIVLGNNWKEGLLKLISPEELPAQFGGTLTDPDGNPKCLTKINYGGEIPKSMY 160 170 180 190 200 210 270 280 290 300 310 320 pF1KSD VRDQVKQQYEHSVQISRGSSHQVEYEILFPGCVLRWQFMSDGADVGFGIFLKTKMGERQR :::::: ::::::::.:::::::::::::::::::::: :::::.:::.::::::::::: NP_001 VRDQVKTQYEHSVQINRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTKMGERQR 220 230 240 250 260 270 330 340 350 360 370 380 pF1KSD AGEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNTYSFIHAKKVNFTVEVLLPDKA :::::.:::.::::.:.:::::.::::. :.:::::::::::.:::::.:::::::::.. NP_001 AGEMTDVLPSQRYNAHMVPEDGNLTCSEAGVYVLRFDNTYSFVHAKKVSFTVEVLLPDEG 280 290 300 310 320 330 390 400 pF1KSD SEEKMKQLGAGTPK .. :.: NP_001 MQKYDKELTPV 340 >>NP_001244308 (OMIM: 612824) SEC14-like protein 3 isofo (341 aa) initn: 1850 init1: 1850 opt: 1858 Z-score: 2275.4 bits: 429.7 E(85289): 5.3e-120 Smith-Waterman score: 1858; 75.1% identity (92.9% similar) in 338 aa overlap (60-397:1-338) 30 40 50 60 70 80 pF1KSD LPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDNIISWQPPEVIQQYLSGGMC .:::: :::.:..::::::::.:. ::.: NP_001 MEFRKTMDIDHILDWQPPEVIQKYMPGGLC 10 20 30 90 100 110 120 130 140 pF1KSD GYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECELLLQECAHQTTKLGRKVETI ::: :::::::::::::: ::::::..:::::.::::.:: .:.:: :: .::.:.::: NP_001 GYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERILHECDLQTERLGKKIETI 40 50 60 70 80 90 150 160 170 180 190 200 pF1KSD TIIYDCEGLGLKHLWKPAVEAYGEFLCMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFL ..:.:::::::::.::: ::.: ::. ..::::::::: ...::: :::::.:::.:::: NP_001 VMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFL 100 110 120 130 140 150 210 220 230 240 250 260 pF1KSD SEDTRKKIMVLGANWKEVLLKHISPDQVPVEYGGTMTDPDGNPKCKSKINYGGDIPRKYY :::::.::.::: :::: ::: :::...:...:::.::::::::: .::::::.::...: NP_001 SEDTRRKIIVLGNNWKEGLLKLISPEELPAQFGGTLTDPDGNPKCLTKINYGGEIPKSMY 160 170 180 190 200 210 270 280 290 300 310 320 pF1KSD VRDQVKQQYEHSVQISRGSSHQVEYEILFPGCVLRWQFMSDGADVGFGIFLKTKMGERQR :::::: ::::::::.:::::::::::::::::::::: :::::.:::.::::::::::: NP_001 VRDQVKTQYEHSVQINRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTKMGERQR 220 230 240 250 260 270 330 340 350 360 370 380 pF1KSD AGEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNTYSFIHAKKVNFTVEVLLPDKA :::::.:::.::::.:.:::::.::::. :.:::::::::::.:::::.:::::::::.. NP_001 AGEMTDVLPSQRYNAHMVPEDGNLTCSEAGVYVLRFDNTYSFVHAKKVSFTVEVLLPDEG 280 290 300 310 320 330 390 400 pF1KSD SEEKMKQLGAGTPK .. :.: NP_001 MQKYDKELTPV 340 403 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:14:46 2016 done: Thu Nov 3 05:14:47 2016 Total Scan time: 8.550 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]