FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1194, 557 aa
1>>>pF1KSDA1194 557 - 557 aa - 557 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5274+/-0.000507; mu= 17.2094+/- 0.031
mean_var=107.8243+/-24.082, 0's: 0 Z-trim(111.3): 249 B-trim: 896 in 1/48
Lambda= 0.123514
statistics sampled from 19486 (19837) to 19486 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.233), width: 16
Scan time: 10.240
The best scores are: opt bits E(85289)
XP_011532908 (OMIM: 608951) PREDICTED: CCR4-NOT tr ( 557) 3712 673.3 5.3e-193
XP_005266010 (OMIM: 608951) PREDICTED: CCR4-NOT tr ( 557) 3712 673.3 5.3e-193
XP_011532909 (OMIM: 608951) PREDICTED: CCR4-NOT tr ( 557) 3712 673.3 5.3e-193
NP_001290170 (OMIM: 608951) CCR4-NOT transcription ( 557) 3712 673.3 5.3e-193
XP_011532907 (OMIM: 608951) PREDICTED: CCR4-NOT tr ( 552) 3660 664.1 3.3e-190
XP_016865159 (OMIM: 608951) PREDICTED: CCR4-NOT tr ( 462) 3097 563.7 4.6e-160
XP_016865160 (OMIM: 608951) PREDICTED: CCR4-NOT tr ( 462) 3097 563.7 4.6e-160
XP_016865161 (OMIM: 608951) PREDICTED: CCR4-NOT tr ( 428) 2763 504.1 3.6e-142
NP_689937 (OMIM: 179555) ras suppressor protein 1 ( 224) 238 53.9 6.4e-07
NP_036557 (OMIM: 179555) ras suppressor protein 1 ( 277) 238 54.0 7.4e-07
NP_036250 (OMIM: 608468) nocturnin [Homo sapiens] ( 431) 233 53.3 1.9e-06
NP_060979 (OMIM: 614854) leucine-rich repeat-conta ( 307) 225 51.7 4e-06
XP_016866486 (OMIM: 608195) PREDICTED: leucine-ric ( 331) 225 51.7 4.2e-06
XP_011513029 (OMIM: 608195) PREDICTED: leucine-ric ( 465) 225 51.9 5.3e-06
XP_011513028 (OMIM: 608195) PREDICTED: leucine-ric ( 524) 225 52.0 5.7e-06
NP_060684 (OMIM: 608195) leucine-rich repeat-conta ( 524) 225 52.0 5.7e-06
NP_062540 (OMIM: 608360,613506) volume-regulated a ( 810) 219 51.1 1.6e-05
XP_006717249 (OMIM: 608360,613506) PREDICTED: volu ( 810) 219 51.1 1.6e-05
XP_011517167 (OMIM: 608360,613506) PREDICTED: volu ( 810) 219 51.1 1.6e-05
NP_001120717 (OMIM: 608360,613506) volume-regulate ( 810) 219 51.1 1.6e-05
XP_011517165 (OMIM: 608360,613506) PREDICTED: volu ( 810) 219 51.1 1.6e-05
XP_011517166 (OMIM: 608360,613506) PREDICTED: volu ( 810) 219 51.1 1.6e-05
XP_005252153 (OMIM: 608360,613506) PREDICTED: volu ( 810) 219 51.1 1.6e-05
XP_005252152 (OMIM: 608360,613506) PREDICTED: volu ( 810) 219 51.1 1.6e-05
NP_001120716 (OMIM: 608360,613506) volume-regulate ( 810) 219 51.1 1.6e-05
XP_016857091 (OMIM: 612890) PREDICTED: volume-regu ( 858) 215 50.4 2.8e-05
NP_060573 (OMIM: 612890) volume-regulated anion ch ( 858) 215 50.4 2.8e-05
XP_016857088 (OMIM: 612890) PREDICTED: volume-regu ( 858) 215 50.4 2.8e-05
XP_016857090 (OMIM: 612890) PREDICTED: volume-regu ( 858) 215 50.4 2.8e-05
XP_011539991 (OMIM: 612890) PREDICTED: volume-regu ( 858) 215 50.4 2.8e-05
NP_001127951 (OMIM: 612890) volume-regulated anion ( 858) 215 50.4 2.8e-05
XP_016857089 (OMIM: 612890) PREDICTED: volume-regu ( 858) 215 50.4 2.8e-05
NP_056171 (OMIM: 607733) protein scribble homolog (1630) 217 51.0 3.3e-05
NP_874365 (OMIM: 607733) protein scribble homolog (1655) 217 51.1 3.4e-05
XP_005252609 (OMIM: 179555) PREDICTED: ras suppres ( 277) 206 48.3 3.9e-05
XP_016862666 (OMIM: 607180) PREDICTED: leucine-ric ( 258) 205 48.1 4.2e-05
XP_011532412 (OMIM: 607180) PREDICTED: leucine-ric ( 371) 205 48.2 5.3e-05
NP_078788 (OMIM: 607180) leucine-rich repeat-conta ( 371) 205 48.2 5.3e-05
NP_001275932 (OMIM: 611066) PH domain leucine-rich (1256) 210 49.7 6.6e-05
NP_055835 (OMIM: 611066) PH domain leucine-rich re (1323) 210 49.7 6.9e-05
NP_001255968 (OMIM: 602775,607721) leucine-rich re ( 536) 204 48.2 7.8e-05
XP_016872192 (OMIM: 602775,607721) PREDICTED: leuc ( 582) 204 48.3 8.2e-05
XP_016872191 (OMIM: 602775,607721) PREDICTED: leuc ( 582) 204 48.3 8.2e-05
NP_001311266 (OMIM: 602775,607721) leucine-rich re ( 582) 204 48.3 8.2e-05
NP_031399 (OMIM: 602775,607721) leucine-rich repea ( 582) 204 48.3 8.2e-05
XP_016872193 (OMIM: 602775,607721) PREDICTED: leuc ( 582) 204 48.3 8.2e-05
NP_001311265 (OMIM: 602775,607721) leucine-rich re ( 582) 204 48.3 8.2e-05
XP_006717379 (OMIM: 610933,614436) PREDICTED: E3 u ( 690) 201 47.8 0.00013
NP_001177652 (OMIM: 610933,614436) E3 ubiquitin-pr ( 696) 201 47.8 0.00013
NP_612370 (OMIM: 610933,614436) E3 ubiquitin-prote ( 723) 201 47.8 0.00014
>>XP_011532908 (OMIM: 608951) PREDICTED: CCR4-NOT transc (557 aa)
initn: 3712 init1: 3712 opt: 3712 Z-score: 3585.9 bits: 673.3 E(85289): 5.3e-193
Smith-Waterman score: 3712; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:1-557)
10 20 30 40 50 60
pF1KSD MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD VVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLEL
490 500 510 520 530 540
550
pF1KSD LLPFLPQVNGIHLPGRR
:::::::::::::::::
XP_011 LLPFLPQVNGIHLPGRR
550
>>XP_005266010 (OMIM: 608951) PREDICTED: CCR4-NOT transc (557 aa)
initn: 3712 init1: 3712 opt: 3712 Z-score: 3585.9 bits: 673.3 E(85289): 5.3e-193
Smith-Waterman score: 3712; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:1-557)
10 20 30 40 50 60
pF1KSD MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD VVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLEL
490 500 510 520 530 540
550
pF1KSD LLPFLPQVNGIHLPGRR
:::::::::::::::::
XP_005 LLPFLPQVNGIHLPGRR
550
>>XP_011532909 (OMIM: 608951) PREDICTED: CCR4-NOT transc (557 aa)
initn: 3712 init1: 3712 opt: 3712 Z-score: 3585.9 bits: 673.3 E(85289): 5.3e-193
Smith-Waterman score: 3712; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:1-557)
10 20 30 40 50 60
pF1KSD MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD VVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLEL
490 500 510 520 530 540
550
pF1KSD LLPFLPQVNGIHLPGRR
:::::::::::::::::
XP_011 LLPFLPQVNGIHLPGRR
550
>>NP_001290170 (OMIM: 608951) CCR4-NOT transcription com (557 aa)
initn: 3712 init1: 3712 opt: 3712 Z-score: 3585.9 bits: 673.3 E(85289): 5.3e-193
Smith-Waterman score: 3712; 100.0% identity (100.0% similar) in 557 aa overlap (1-557:1-557)
10 20 30 40 50 60
pF1KSD MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD VVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD NYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLEL
490 500 510 520 530 540
550
pF1KSD LLPFLPQVNGIHLPGRR
:::::::::::::::::
NP_001 LLPFLPQVNGIHLPGRR
550
>>XP_011532907 (OMIM: 608951) PREDICTED: CCR4-NOT transc (552 aa)
initn: 2757 init1: 2660 opt: 3660 Z-score: 3535.9 bits: 664.1 E(85289): 3.3e-190
Smith-Waterman score: 3660; 98.9% identity (99.1% similar) in 557 aa overlap (1-557:1-552)
10 20 30 40 50 60
pF1KSD MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEP
:::::::::::::::::::::::::::::::::::::: .::::::::::::::::
XP_011 QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLS-----VTTEQPPPRSWIMLQEP
130 140 150 160 170
190 200 210 220 230 240
pF1KSD DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KSD EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KSD HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KSD VVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYT
420 430 440 450 460 470
490 500 510 520 530 540
pF1KSD NYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLEL
480 490 500 510 520 530
550
pF1KSD LLPFLPQVNGIHLPGRR
:::::::::::::::::
XP_011 LLPFLPQVNGIHLPGRR
540 550
>>XP_016865159 (OMIM: 608951) PREDICTED: CCR4-NOT transc (462 aa)
initn: 3097 init1: 3097 opt: 3097 Z-score: 2994.7 bits: 563.7 E(85289): 4.6e-160
Smith-Waterman score: 3097; 100.0% identity (100.0% similar) in 462 aa overlap (96-557:1-462)
70 80 90 100 110 120
pF1KSD IPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTL
::::::::::::::::::::::::::::::
XP_016 MVSLRELHLNNNLLRVLPFELGKLFQLQTL
10 20 30
130 140 150 160 170 180
pF1KSD GLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEPDRTRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEPDRTRP
40 50 60 70 80 90
190 200 210 220 230 240
pF1KSD TALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETEQ
100 110 120 130 140 150
250 260 270 280 290 300
pF1KSD YYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQL
160 170 180 190 200 210
310 320 330 340 350 360
pF1KSD AMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANAHMHWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANAHMHWD
220 230 240 250 260 270
370 380 390 400 410 420
pF1KSD PEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSGVVEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSGVVEYL
280 290 300 310 320 330
430 440 450 460 470 480
pF1KSD STGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYTNYTFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYTNYTFD
340 350 360 370 380 390
490 500 510 520 530 540
pF1KSD FKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFL
400 410 420 430 440 450
550
pF1KSD PQVNGIHLPGRR
::::::::::::
XP_016 PQVNGIHLPGRR
460
>>XP_016865160 (OMIM: 608951) PREDICTED: CCR4-NOT transc (462 aa)
initn: 3097 init1: 3097 opt: 3097 Z-score: 2994.7 bits: 563.7 E(85289): 4.6e-160
Smith-Waterman score: 3097; 100.0% identity (100.0% similar) in 462 aa overlap (96-557:1-462)
70 80 90 100 110 120
pF1KSD IPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTL
::::::::::::::::::::::::::::::
XP_016 MVSLRELHLNNNLLRVLPFELGKLFQLQTL
10 20 30
130 140 150 160 170 180
pF1KSD GLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEPDRTRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEPDRTRP
40 50 60 70 80 90
190 200 210 220 230 240
pF1KSD TALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETEQ
100 110 120 130 140 150
250 260 270 280 290 300
pF1KSD YYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQL
160 170 180 190 200 210
310 320 330 340 350 360
pF1KSD AMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANAHMHWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANAHMHWD
220 230 240 250 260 270
370 380 390 400 410 420
pF1KSD PEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSGVVEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSGVVEYL
280 290 300 310 320 330
430 440 450 460 470 480
pF1KSD STGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYTNYTFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYTNYTFD
340 350 360 370 380 390
490 500 510 520 530 540
pF1KSD FKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFL
400 410 420 430 440 450
550
pF1KSD PQVNGIHLPGRR
::::::::::::
XP_016 PQVNGIHLPGRR
460
>>XP_016865161 (OMIM: 608951) PREDICTED: CCR4-NOT transc (428 aa)
initn: 2763 init1: 2763 opt: 2763 Z-score: 2673.4 bits: 504.1 E(85289): 3.6e-142
Smith-Waterman score: 2763; 100.0% identity (100.0% similar) in 420 aa overlap (1-420:1-420)
10 20 30 40 50 60
pF1KSD MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD VVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYT
XP_016 YNRLHFLF
>>NP_689937 (OMIM: 179555) ras suppressor protein 1 isof (224 aa)
initn: 323 init1: 219 opt: 238 Z-score: 245.2 bits: 53.9 E(85289): 6.4e-07
Smith-Waterman score: 238; 36.2% identity (68.1% similar) in 138 aa overlap (42-172:72-205)
20 30 40 50 60 70
pF1KSD RRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSDNSLSRIPSDIA
:: .... :: : ::.::::.. .: ::.
NP_689 MNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG
50 60 70 80 90 100
80 90 100 110 120
pF1KSD KLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKL---FQLQTLGLK
:: .: :.: .: . ::: :.:....:.:::...: : ::: :::.: : :.. .
NP_689 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQVFKAE
110 120 130 140 150 160
130 140 150 160 170 180
pF1KSD GNPLTQDILNLYQEPDGTRRLLNYLLDN----LSGTAKRITTEQPPPRSWIMLQEPDRTR
.:: . : . .: :. ....:. .. : : ... .. ::.
NP_689 NNPWVTPIADQFQL--GVSHVFEYIRSETYKYLYG--RHMQANPEPPKKNNDKSKKISRK
170 180 190 200 210
190 200 210 220 230 240
pF1KSD PTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETE
NP_689 PLAAKNR
220
>>NP_036557 (OMIM: 179555) ras suppressor protein 1 isof (277 aa)
initn: 376 init1: 219 opt: 238 Z-score: 244.1 bits: 54.0 E(85289): 7.4e-07
Smith-Waterman score: 238; 36.2% identity (68.1% similar) in 138 aa overlap (42-172:125-258)
20 30 40 50 60 70
pF1KSD RRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSDNSLSRIPSDIA
:: .... :: : ::.::::.. .: ::.
NP_036 MNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG
100 110 120 130 140 150
80 90 100 110 120
pF1KSD KLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKL---FQLQTLGLK
:: .: :.: .: . ::: :.:....:.:::...: : ::: :::.: : :.. .
NP_036 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQVFKAE
160 170 180 190 200 210
130 140 150 160 170 180
pF1KSD GNPLTQDILNLYQEPDGTRRLLNYLLDN----LSGTAKRITTEQPPPRSWIMLQEPDRTR
.:: . : . .: :. ....:. .. : : ... .. ::.
NP_036 NNPWVTPIADQFQL--GVSHVFEYIRSETYKYLYG--RHMQANPEPPKKNNDKSKKISRK
220 230 240 250 260 270
190 200 210 220 230 240
pF1KSD PTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETE
NP_036 PLAAKNR
>--
initn: 193 init1: 171 opt: 202 Z-score: 209.4 bits: 47.6 E(85289): 6.3e-05
Smith-Waterman score: 202; 38.2% identity (76.4% similar) in 89 aa overlap (47-135:36-124)
20 30 40 50 60 70
pF1KSD IMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNL
:..:.:.: : :: :.:. .: .::.:.::
NP_036 KKLVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNL
10 20 30 40 50 60
80 90 100 110 120 130
pF1KSD VYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLGLKGNPLTQDI
:.. .:.:. ::...... .:..:.:. : : .:: .:.: :..: : : :...
NP_036 EVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENS
70 80 90 100 110 120
140 150 160 170 180 190
pF1KSD LNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEPDRTRPTALFSVMCYNV
NP_036 LPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKEL
130 140 150 160 170 180
557 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:17:52 2016 done: Thu Nov 3 05:17:54 2016
Total Scan time: 10.240 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]