FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1195, 709 aa 1>>>pF1KSDA1195 709 - 709 aa - 709 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8400+/-0.00096; mu= 17.6346+/- 0.058 mean_var=83.1706+/-16.413, 0's: 0 Z-trim(105.9): 25 B-trim: 41 in 1/51 Lambda= 0.140634 statistics sampled from 8667 (8675) to 8667 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.635), E-opt: 0.2 (0.266), width: 16 Scan time: 3.840 The best scores are: opt bits E(32554) CCDS33835.1 FBXO40 gene_id:51725|Hs108|chr3 ( 709) 4838 991.9 0 CCDS5208.1 FBXO30 gene_id:84085|Hs108|chr6 ( 745) 601 132.3 2.6e-30 >>CCDS33835.1 FBXO40 gene_id:51725|Hs108|chr3 (709 aa) initn: 4838 init1: 4838 opt: 4838 Z-score: 5303.9 bits: 991.9 E(32554): 0 Smith-Waterman score: 4838; 100.0% identity (100.0% similar) in 709 aa overlap (1-709:1-709) 10 20 30 40 50 60 pF1KSD MGKARRSPPGHHRHCEGCFNRHCHIPVEPNTSCLVISCHLLCGATFHMCKEAEHQLLCPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MGKARRSPPGHHRHCEGCFNRHCHIPVEPNTSCLVISCHLLCGATFHMCKEAEHQLLCPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD EQVPCLNSEYGCPLSMSRHKLAKHLQVCPASVVCCSMEWNRWPNVDSETTLHENIMKETP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 EQVPCLNSEYGCPLSMSRHKLAKHLQVCPASVVCCSMEWNRWPNVDSETTLHENIMKETP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD SEECLDTALALQDQKVLFRSLKMVELFPETREATEEEPTMNGETSVEEMGGAVGGVDIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SEECLDTALALQDQKVLFRSLKMVELFPETREATEEEPTMNGETSVEEMGGAVGGVDIGL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VPHGLSATNGEMAELSQEEREVLAKTKEGMDLVKFGQWENIFSKEHAASALTNSSASCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VPHGLSATNGEMAELSQEEREVLAKTKEGMDLVKFGQWENIFSKEHAASALTNSSASCES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KNKNDSEKEQISSGHNMVEGEGAPKKKEPQENQKQQDVRTAMETTGLAPWQDGVLERLKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KNKNDSEKEQISSGHNMVEGEGAPKKKEPQENQKQQDVRTAMETTGLAPWQDGVLERLKT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD AVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGKLEAQEVKTVYTFKVPVSYCGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 AVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGKLEAQEVKTVYTFKVPVSYCGKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD ARLGDAMLSCKPSEHKAVDTSDLGITVEDLPKSDLIKTTLQCALERELKGHVISESRSID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 ARLGDAMLSCKPSEHKAVDTSDLGITVEDLPKSDLIKTTLQCALERELKGHVISESRSID 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GLFMDFATQTYNFEPEQFSSGTVLADLTAATPGGLHVELHSECVTRRHNKSSSAFTFTCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GLFMDFATQTYNFEPEQFSSGTVLADLTAATPGGLHVELHSECVTRRHNKSSSAFTFTCN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD KFFRRDEFPLHFKNVHTDIQSCLNGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KFFRRDEFPLHFKNVHTDIQSCLNGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD KTFAIKPEVAPELSEGRKNNHLLGHGGKSQNSLTSLPLEILKYIAGFLDSVSLAQLSQVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KTFAIKPEVAPELSEGRKNNHLLGHGGKSQNSLTSLPLEILKYIAGFLDSVSLAQLSQVS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VLMRNICATLLQERGMVLLQWKKKRYSHGGTSWRVHREIWQFSSLFSKIKSWEFNEVTSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VLMRNICATLLQERGMVLLQWKKKRYSHGGTSWRVHREIWQFSSLFSKIKSWEFNEVTSM 610 620 630 640 650 660 670 680 690 700 pF1KSD SEHLKSCPFNIVEHKTDPILLTSMCQPREQARESLVSTFRIRPRGRYVS ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 SEHLKSCPFNIVEHKTDPILLTSMCQPREQARESLVSTFRIRPRGRYVS 670 680 690 700 >>CCDS5208.1 FBXO30 gene_id:84085|Hs108|chr6 (745 aa) initn: 1544 init1: 578 opt: 601 Z-score: 657.6 bits: 132.3 E(32554): 2.6e-30 Smith-Waterman score: 1462; 35.6% identity (65.4% similar) in 739 aa overlap (11-693:6-733) 10 20 30 40 50 60 pF1KSD MGKARRSPPGHHRHCEGCFNRHCHIPVEPNTSCLVISCHLLCGATFHMCKEAEHQLLCPL .: :: .: .:.: ::. :: .:.: :.:::.:: :: ::.::::. CCDS52 MEEELQHSHCVNCVSRRCMTRPEPGISCDLIGCPLVCGAVFHSCKADEHRLLCPF 10 20 30 40 50 70 80 90 100 110 120 pF1KSD EQVPCLNSEYGCPLSMSRHKLAKHLQVCPASVVCCSMEWNRWPNVDSETTLHENIMKETP :.::::::..:::..:.:.:.:.::..::::::::.::::::: .. .::. ... CCDS52 ERVPCLNSDFGCPFTMARNKVAEHLEMCPASVVCCTMEWNRWPVSYADRKSYENLSRDVD 60 70 80 90 100 110 130 140 150 160 170 pF1KSD SEECLDTALALQDQKVLFRSLKMVELFPE-TREATEEEPTMNGETSVEEMGGAVGGVDI- :: :::::::..:..:::.. .. . : .... . .. ..:: :. : : :.. CCDS52 EVAQLDMALALQDQRMLLESLKVATMMSKATDKVSKPREQISVKSSVPEIPHANGLVSVD 120 130 140 150 160 170 180 190 200 210 pF1KSD ----GLVPHGLSATNGEMAE----LSQEEREV-------------LAKTKEGMDLVKFGQ : . .. :. .: :. :.. ...:... .. . CCDS52 EESYGALYQATVETTRSLAAALDILNTATRDIGMLNTSVPNDMDEQQNARESLEDQNLKD 180 190 200 210 220 230 220 230 240 250 260 pF1KSD WENIFSKEHAASAL-----TNSSASCESKNKNDSEKEQISSGHNMVE-GEGAPKK----K .... .: .: . ::..:. :.....: . .:... .: : . . CCDS52 QDHLYEEEIGAVGGIDYNDTNQNAQSEQNGSSDLLCDLNTSSYDTSALCNGFPLENICTQ 240 250 260 270 280 290 270 280 290 300 310 320 pF1KSD EPQENQKQQ-DVRTAMETTG-LAPWQDGVLERLKT-AVDAKDYNMY---LVHNGRMLIHF ..::. . : . . :.: . .::. . .. :: :. .. . :: .. CCDS52 VIDQNQNLHGDSKQSNLTNGDCVASSDGTSKPSSSLAVAAQLREIIPSSALPNGT--VQH 300 310 320 330 340 350 330 340 350 360 370 380 pF1KSD GQMPACTPKERDFVYGKLEAQEVKTVYTFKVPVSYCGKRARLGDAMLSCKPSEHKAVDTS :: : .. . :.. .::.: ... :. . :... : ::.: :::::: CCDS52 ILMPD-DEGEGELCWKKVDLGDVKNVDVLS--FSHAPSFNFLSNSCWS-KPKEDKAVDTS 360 370 380 390 400 390 400 410 420 430 pF1KSD DLGITVED---LPKSDLIKTTLQCALERELKGHVISESRSIDGLFMDFATQTYNFEPEQF :: .. :: : ::: ..: : :. ::.:: : .: .:::... . CCDS52 DLEVA-EDPMGLQGIDLITAALLFCLGDSPGGRGISDSRMADIYHIDVGTQTFSLPSAIL 410 420 430 440 450 460 440 450 460 470 480 pF1KSD SSGTVLADLTAAT-----------PGG---LHVELHSECVTRRHNKSSSAFTFTCNKFFR ...:.......:. :. : ..: :::.: . :. : :::.:...:: CCDS52 ATSTMVGEIASASACDHANPQLSNPSPFQTLGLDLVLECVARYQPKQRSMFTFVCGQLFR 470 480 490 500 510 520 490 500 510 520 530 540 pF1KSD RDEFPLHFKNVHTDIQSCLNGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQELKTFA : :: :::::: ::.. ::::...:::::: :::. : .: : : ::.:....:..:. CCDS52 RKEFSSHFKNVHGDIHAGLNGWMEQRCPLAYYGCTYSQRRFCPSIQGAKIIHDRHLRSFG 530 540 550 560 570 580 550 560 570 580 590 600 pF1KSD IKPEVAPELSEGRKNNHLLGHGGKSQNSLTSLPLEILKYIAGFLDSVSLAQLSQVSVLMR ..: :. : : .: : : .. :.:::.:.:..::::::. :: ::: :: ::: CCDS52 VQPCVSTVLVEPARNCVL----GLHNDHLSSLPFEVLQHIAGFLDGFSLCQLSCVSKLMR 590 600 610 620 630 640 610 620 630 640 650 660 pF1KSD NICATLLQERGMVLLQWKKKRYSHGGTSWRVHREIWQFSSLFSKIKSWEFNEVTSMSEHL ..:..::: ::::.::: :..: .:..::......:.::. : ... :.: .. ::..:: CCDS52 DVCGSLLQSRGMVILQWGKRKYPEGNSSWQIKEKVWRFSTAFCSVNEWKFADILSMADHL 650 660 670 680 690 700 670 680 690 700 pF1KSD KSCPFNIVEHKTDPILLTSMCQPREQARESLVSTFRIRPRGRYVS :.: .:.::.. . : : :: :: ..: CCDS52 KKCSYNVVEKREEAIPLPCMCVTRELTKEGRSLRSVLKPVL 710 720 730 740 709 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:18:34 2016 done: Thu Nov 3 05:18:35 2016 Total Scan time: 3.840 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]