Result of FASTA (omim) for
pF1KSDA1214
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1214, 396 aa
1>>>pF1KSDA1214 396 - 396 aa - 396 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7613+/-0.000367; mu= 15.7270+/- 0.023
mean_var=110.2542+/-22.559, 0's: 0 Z-trim(115.6): 252 B-trim: 131 in 1/52
Lambda= 0.122145
statistics sampled from 25836 (26132) to 25836 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.306), width: 16
Scan time: 8.300
The best scores are: opt bits E(85289)
NP_078815 (OMIM: 300439) E3 ubiquitin-protein liga ( 402) 451 90.4 8.1e-18
NP_919445 (OMIM: 300439) E3 ubiquitin-protein liga ( 428) 451 90.5 8.5e-18
NP_001307294 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 283 60.7 5.6e-09
NP_001307292 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 283 60.7 5.6e-09
NP_001307291 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 283 60.7 5.6e-09
NP_001307293 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 283 60.7 5.6e-09
XP_016879916 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 350) 283 60.8 6e-09
NP_001307285 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 283 60.8 6e-09
NP_001307290 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 283 60.8 6e-09
NP_001307286 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 283 60.8 6e-09
NP_056343 (OMIM: 610431) E3 ubiquitin-protein liga ( 350) 283 60.8 6e-09
NP_001307287 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 283 60.8 6e-09
NP_001307289 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 283 60.8 6e-09
NP_001307288 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 283 60.8 6e-09
NP_115549 (OMIM: 612062) E3 ubiquitin-protein liga ( 836) 264 57.8 1.1e-07
XP_011528739 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 264 57.8 1.1e-07
XP_011528740 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 264 57.8 1.1e-07
XP_011528738 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 264 57.8 1.1e-07
XP_016884479 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 264 57.8 1.1e-07
XP_011528737 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 264 57.8 1.1e-07
XP_016861149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 250) 257 56.0 1.1e-07
XP_016861147 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 257 56.1 1.2e-07
XP_005247149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 257 56.1 1.2e-07
XP_011510678 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 257 56.1 1.2e-07
XP_016861146 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 257 56.1 1.2e-07
XP_016861145 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 257 56.1 1.2e-07
XP_016861148 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 257 56.1 1.2e-07
NP_001193927 (OMIM: 612062) E3 ubiquitin-protein l ( 936) 264 57.8 1.2e-07
XP_016861150 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 193) 254 55.4 1.4e-07
NP_009213 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 257 56.2 1.5e-07
XP_011510675 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 257 56.2 1.5e-07
NP_899237 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 257 56.2 1.5e-07
XP_016861144 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 257 56.2 1.5e-07
XP_011510676 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 257 56.2 1.5e-07
XP_016861143 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 257 56.2 1.5e-07
XP_016879917 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 227) 242 53.4 6.6e-07
XP_016869786 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402) 214 48.7 3e-05
XP_016869785 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402) 214 48.7 3e-05
NP_919309 (OMIM: 612488) E3 ubiquitin-protein liga ( 432) 214 48.7 3.2e-05
XP_005251423 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 214 48.7 3.2e-05
XP_016869784 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 214 48.7 3.2e-05
XP_005251425 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 214 48.7 3.2e-05
XP_006716784 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 214 48.7 3.2e-05
XP_011516014 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 214 48.7 3.2e-05
XP_011516015 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 214 48.7 3.2e-05
NP_919313 (OMIM: 612488) E3 ubiquitin-protein liga ( 432) 214 48.7 3.2e-05
XP_005251424 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432) 214 48.7 3.2e-05
NP_919311 (OMIM: 612488) E3 ubiquitin-protein liga ( 432) 214 48.7 3.2e-05
XP_016869783 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 444) 214 48.7 3.2e-05
NP_001292474 (OMIM: 612482,617108) E3 ubiquitin-pr ( 656) 216 49.2 3.3e-05
>>NP_078815 (OMIM: 300439) E3 ubiquitin-protein ligase R (402 aa)
initn: 750 init1: 429 opt: 451 Z-score: 440.9 bits: 90.4 E(85289): 8.1e-18
Smith-Waterman score: 715; 39.4% identity (58.5% similar) in 386 aa overlap (17-360:11-363)
10 20 30 40 50
pF1KSD MAMSLIQACCSLALSTWLLS-FCFVHLLCLDFTVAEKEEWYTAFVNITYAEPAPDPGAGA
::: : :. . .:.. .:.:..:: . . . :
NP_078 MNQENRSSFFWLLVIFTFLLKITASFSM-------SAYVTVTYYNETSNYTA--
10 20 30 40
60 70 80 90 100 110
pF1KSD AGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDPNTKFAAPTRGKNWIA
: ::: :: :: .: : :: . .. ::: ::.:. : :::
NP_078 ---------IETCECGVYGLASPVANAMG-VVGIPKNNNYQACDHNTEFSNTK--KPWIA
50 60 70 80 90
120 130 140 150 160 170
pF1KSD LIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNTNETITMPHAGVEDIVAIMIPEPKGKEI
:: .::::. .::..: .::.::::.:. . :.:: : . :. ::::::: . :: .:
NP_078 LIERGNCTFSEKIQTAGRRNADAVVIYNAPETGNQTIQMANFGAVDIVAIMIGNLKGTKI
100 110 120 130 140 150
180 190 200
pF1KSD VSLLERNITVTMYITIGTRN---LQKY-------------------------RRLGDA--
.. ..:.: ::: : .: .. ...: ::: .:
NP_078 LQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARA
160 170 180 190 200 210
210 220 230 240 250
pF1KSD -----------AKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILPCRHLF
:::::..::.::.:.:::: : :.:::::: :::::.:::: : :.:
NP_078 QSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIF
220 230 240 250 260 270
260 270 280 290 300 310
pF1KSD HKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGPPTNQITGASDT
::.:::::::.:::::::: .::::::: ... : :: : .:.:......
NP_078 HKTCVDPWLLEHRTCPMCKCDILKALGIEVDVE-------DGSVSLQVPVSNEISNSASS
280 290 300 310 320
320 330 340 350 360 370
pF1KSD TVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSDSDISLIMAMEV
.: . . : .. :: :: : : : :..: :
NP_078 --HEEDNRSETASSGYAS---VQGTDEPPLEEHVQSTNESLQLVNHEANSVAVDVIPHVD
330 340 350 360 370 380
380 390
pF1KSD GLSDVELSTDQDCEEVKS
NP_078 NPTFEEDETPNQETAVREIKS
390 400
>>NP_919445 (OMIM: 300439) E3 ubiquitin-protein ligase R (428 aa)
initn: 744 init1: 429 opt: 451 Z-score: 440.5 bits: 90.5 E(85289): 8.5e-18
Smith-Waterman score: 695; 38.3% identity (59.4% similar) in 392 aa overlap (18-360:20-389)
10 20 30 40 50
pF1KSD MAMSLIQACCSLALSTWLLSFCFVHLLCLDFTVAEKEE--WYTAFVNITYAEPAPDPG
::..::. : . .. : : ::..:... :
NP_919 MGPPPGAGVSCRGGCGFSRLLAWCFLLALSPQAPGSRGAEAVW-TAYLNVSWRVPHT---
10 20 30 40 50
60 70 80 90 100 110
pF1KSD AGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDPNTKFAAPTR-GK
: . : .: : ::. :: . . : .: .. ::.:.:.:..:: :.
NP_919 ------GVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD ----NWIALIPKGN-CTYRDKIRNAFLQNASAVVIFNVGSNTNETITMPHAGVEDIVAIM
.:.::: .:. ::. :::. :. ..::..:::: .. ::.: : : :. ::::::
NP_919 TVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIM
120 130 140 150 160 170
180 190 200
pF1KSD IPEPKGKEIVSLLERNITVTMYITIGTRN---LQKY------------------------
: . :: .:.. ..:.: ::: : .: .. ...:
NP_919 IGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYS
180 190 200 210 220 230
210 220 230 240
pF1KSD -RRLGDA-------------AKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVV
::: .: :::::..::.::.:.:::: : :.:::::: :::::.:
NP_919 ARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLV
240 250 260 270 280 290
250 260 270 280 290 300
pF1KSD RILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGPPT
::: : :.:::.:::::::.:::::::: .::::::: ... : :: : .
NP_919 RILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVE-------DGSVSLQVPVS
300 310 320 330 340
310 320 330 340 350 360
pF1KSD NQITGASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSDSD
:.:...... .: . . : .. :: :: : : : :..: :
NP_919 NEISNSASS--HEEDNRSETASSGYAS---VQGTDEPPLEEHVQSTNESLQLVNHEANSV
350 360 370 380 390
370 380 390
pF1KSD ISLIMAMEVGLSDVELSTDQDCEEVKS
NP_919 AVDVIPHVDNPTFEEDETPNQETAVREIKS
400 410 420
>>NP_001307294 (OMIM: 610431) E3 ubiquitin-protein ligas (315 aa)
initn: 312 init1: 168 opt: 283 Z-score: 282.2 bits: 60.7 E(85289): 5.6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:10-292)
50 60 70 80 90 100
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
.: .. .: .: :: ::.:
NP_001 MDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
10 20 30
110 120 130 140 150
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
::. :. .:::. . .:.. :. :: . .:.:. ::.:: ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
40 50 60 70 80 90
160 170 180 190
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
: .: . . : . :... : :: ... . . .. . .:. .:
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
100 110 120 130 140 150
200 210 220 230 240 250
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
.: .:. .:: .. ..: :.. : : . ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
160 170 180 190 200 210
260 270 280 290 300
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
: : .:. :::::: . : :::.::. . .. : . : .. . ::. : : :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
220 230 240 250 260
310 320 330 340 350 360
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
.. : .:. :. : .: ::
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
270 280 290 300 310
>>NP_001307292 (OMIM: 610431) E3 ubiquitin-protein ligas (315 aa)
initn: 312 init1: 168 opt: 283 Z-score: 282.2 bits: 60.7 E(85289): 5.6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:10-292)
50 60 70 80 90 100
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
.: .. .: .: :: ::.:
NP_001 MDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
10 20 30
110 120 130 140 150
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
::. :. .:::. . .:.. :. :: . .:.:. ::.:: ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
40 50 60 70 80 90
160 170 180 190
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
: .: . . : . :... : :: ... . . .. . .:. .:
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
100 110 120 130 140 150
200 210 220 230 240 250
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
.: .:. .:: .. ..: :.. : : . ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
160 170 180 190 200 210
260 270 280 290 300
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
: : .:. :::::: . : :::.::. . .. : . : .. . ::. : : :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
220 230 240 250 260
310 320 330 340 350 360
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
.. : .:. :. : .: ::
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
270 280 290 300 310
>>NP_001307291 (OMIM: 610431) E3 ubiquitin-protein ligas (315 aa)
initn: 312 init1: 168 opt: 283 Z-score: 282.2 bits: 60.7 E(85289): 5.6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:10-292)
50 60 70 80 90 100
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
.: .. .: .: :: ::.:
NP_001 MDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
10 20 30
110 120 130 140 150
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
::. :. .:::. . .:.. :. :: . .:.:. ::.:: ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
40 50 60 70 80 90
160 170 180 190
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
: .: . . : . :... : :: ... . . .. . .:. .:
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
100 110 120 130 140 150
200 210 220 230 240 250
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
.: .:. .:: .. ..: :.. : : . ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
160 170 180 190 200 210
260 270 280 290 300
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
: : .:. :::::: . : :::.::. . .. : . : .. . ::. : : :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
220 230 240 250 260
310 320 330 340 350 360
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
.. : .:. :. : .: ::
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
270 280 290 300 310
>>NP_001307293 (OMIM: 610431) E3 ubiquitin-protein ligas (315 aa)
initn: 312 init1: 168 opt: 283 Z-score: 282.2 bits: 60.7 E(85289): 5.6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:10-292)
50 60 70 80 90 100
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
.: .. .: .: :: ::.:
NP_001 MDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
10 20 30
110 120 130 140 150
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
::. :. .:::. . .:.. :. :: . .:.:. ::.:: ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
40 50 60 70 80 90
160 170 180 190
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
: .: . . : . :... : :: ... . . .. . .:. .:
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
100 110 120 130 140 150
200 210 220 230 240 250
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
.: .:. .:: .. ..: :.. : : . ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
160 170 180 190 200 210
260 270 280 290 300
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
: : .:. :::::: . : :::.::. . .. : . : .. . ::. : : :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
220 230 240 250 260
310 320 330 340 350 360
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
.. : .:. :. : .: ::
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
270 280 290 300 310
>>XP_016879916 (OMIM: 610431) PREDICTED: E3 ubiquitin-pr (350 aa)
initn: 290 init1: 168 opt: 283 Z-score: 281.6 bits: 60.8 E(85289): 6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:45-327)
50 60 70 80 90 100
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
.: .. .: .: :: ::.:
XP_016 VLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
20 30 40 50 60 70
110 120 130 140 150
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
::. :. .:::. . .:.. :. :: . .:.:. ::.:: ..
XP_016 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
80 90 100 110 120 130
160 170 180 190
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
: .: . . : . :... : :: ... . . .. . .:. .:
XP_016 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
140 150 160 170 180 190
200 210 220 230 240 250
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
.: .:. .:: .. ..: :.. : : . ...: ::.:.. :. .: .:.::
XP_016 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
200 210 220 230 240
260 270 280 290 300
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
: : .:. :::::: . : :::.::. . .. : . : .. . ::. : : :.
XP_016 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
.. : .:. :. : .: ::
XP_016 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
310 320 330 340 350
>>NP_001307285 (OMIM: 610431) E3 ubiquitin-protein ligas (350 aa)
initn: 290 init1: 168 opt: 283 Z-score: 281.6 bits: 60.8 E(85289): 6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:45-327)
50 60 70 80 90 100
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
.: .. .: .: :: ::.:
NP_001 VLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
20 30 40 50 60 70
110 120 130 140 150
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
::. :. .:::. . .:.. :. :: . .:.:. ::.:: ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
80 90 100 110 120 130
160 170 180 190
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
: .: . . : . :... : :: ... . . .. . .:. .:
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
140 150 160 170 180 190
200 210 220 230 240 250
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
.: .:. .:: .. ..: :.. : : . ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
200 210 220 230 240
260 270 280 290 300
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
: : .:. :::::: . : :::.::. . .. : . : .. . ::. : : :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
.. : .:. :. : .: ::
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
310 320 330 340 350
>>NP_001307290 (OMIM: 610431) E3 ubiquitin-protein ligas (350 aa)
initn: 290 init1: 168 opt: 283 Z-score: 281.6 bits: 60.8 E(85289): 6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:45-327)
50 60 70 80 90 100
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
.: .. .: .: :: ::.:
NP_001 VLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
20 30 40 50 60 70
110 120 130 140 150
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
::. :. .:::. . .:.. :. :: . .:.:. ::.:: ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
80 90 100 110 120 130
160 170 180 190
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
: .: . . : . :... : :: ... . . .. . .:. .:
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
140 150 160 170 180 190
200 210 220 230 240 250
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
.: .:. .:: .. ..: :.. : : . ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
200 210 220 230 240
260 270 280 290 300
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
: : .:. :::::: . : :::.::. . .. : . : .. . ::. : : :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
.. : .:. :. : .: ::
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
310 320 330 340 350
>>NP_001307286 (OMIM: 610431) E3 ubiquitin-protein ligas (350 aa)
initn: 290 init1: 168 opt: 283 Z-score: 281.6 bits: 60.8 E(85289): 6e-09
Smith-Waterman score: 331; 27.0% identity (54.6% similar) in 293 aa overlap (77-330:45-327)
50 60 70 80 90 100
pF1KSD TYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDP-N
.: .. .: .: :: ::.:
NP_001 VLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV---EAHPDNACSPIA
20 30 40 50 60 70
110 120 130 140 150
pF1KSD TKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNT-----------NE
::. :. .:::. . .:.. :. :: . .:.:. ::.:: ..
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQ
80 90 100 110 120 130
160 170 180 190
pF1KSD TITMPHAGV-----EDIVAIMIPEPKGKEIVSLLERNITVTMYIT-----IG--------
: .: . . : . :... : :: ... . . .. . .:. .:
NP_001 QIWIPSVFIGERSSEYLRALFVYE-KGARVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGA
140 150 160 170 180 190
200 210 220 230 240 250
pF1KSD ---TRNLQKYRRLGDAAKKAISKLQIRTIKKGDKETESDFDNCAVCIEGYKPNDVVRILP
.: .:. .:: .. ..: :.. : : . ...: ::.:.. :. .: .:.::
NP_001 VMIARCIQHRKRL---QRNRLTKEQLKQIPTHDYQKGDQYDVCAICLDEYEDGDKLRVLP
200 210 220 230 240
260 270 280 290 300
pF1KSD CRHLFHKSCVDPWLLDHR-TCPMCKMNILKALGIPPNADCMDDLPTDFEGSLGGP---PT
: : .:. :::::: . : :::.::. . .. : . : .. . ::. : : :.
NP_001 CAHAYHSRCVDPWLTQTRKTCPICKQPVHRG---PGDEDQEEETQGQEEGDEGEPRDHPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD NQITG--ASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEGDVIFTTNSEQEPAVSSD
.. : .:. :. : .: ::
NP_001 SERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
310 320 330 340 350
396 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:24:13 2016 done: Thu Nov 3 05:24:15 2016
Total Scan time: 8.300 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]