FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1217, 1264 aa 1>>>pF1KSDA1217 1264 - 1264 aa - 1264 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.0645+/-0.00105; mu= -11.1491+/- 0.064 mean_var=409.5988+/-83.933, 0's: 0 Z-trim(115.4): 21 B-trim: 0 in 0/53 Lambda= 0.063372 statistics sampled from 15922 (15943) to 15922 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.49), width: 16 Scan time: 4.090 The best scores are: opt bits E(32554) CCDS41496.1 KIAA1217 gene_id:56243|Hs108|chr10 (1264) 8330 776.5 0 CCDS31165.1 KIAA1217 gene_id:56243|Hs108|chr10 (1943) 6987 653.9 1.2e-186 CCDS60505.1 KIAA1217 gene_id:56243|Hs108|chr10 ( 866) 3832 365.2 4.1e-100 CCDS60501.1 KIAA1217 gene_id:56243|Hs108|chr10 (1349) 3664 350.0 2.5e-95 CCDS60504.1 KIAA1217 gene_id:56243|Hs108|chr10 ( 932) 3571 341.4 6.6e-93 CCDS60502.1 KIAA1217 gene_id:56243|Hs108|chr10 (1374) 3264 313.4 2.6e-84 CCDS45660.1 SRCIN1 gene_id:80725|Hs108|chr17 (1183) 1228 127.2 2.5e-28 >>CCDS41496.1 KIAA1217 gene_id:56243|Hs108|chr10 (1264 aa) initn: 8330 init1: 8330 opt: 8330 Z-score: 4130.9 bits: 776.5 E(32554): 0 Smith-Waterman score: 8330; 100.0% identity (100.0% similar) in 1264 aa overlap (1-1264:1-1264) 10 20 30 40 50 60 pF1KSD MQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTRSPKLSHSPQPPSLGDPVEHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MQTSEMDRKREAFLEHLKQKYPHHASAIMGHQERLRDQTRSPKLSHSPQPPSLGDPVEHL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD SETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SETSADSLEAMSEGDAPTPFSRGSRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD PNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PNEITSADTIRALFVSAFPQQLTMKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD VYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 VYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD HSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRDVKPDEDMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 HSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRDVKPDEDMS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD PDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRETR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTATIPKDRETR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD ERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMKTTANRNHTDSAGTPHVSGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 ERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMKTTANRNHTDSAGTPHVSGGK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD MLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELLRAMMKK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD AELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVEDLKKDST 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD AASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLKEEPHKL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD DSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAAHTSG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD QPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVASSPAVP 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 QEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKRQNLD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD HYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 HYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQTRATKYP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD AEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMSAKNRPG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KSD TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KSD GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KSD PQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTA 1210 1220 1230 1240 1250 1260 pF1KSD KETS :::: CCDS41 KETS >>CCDS31165.1 KIAA1217 gene_id:56243|Hs108|chr10 (1943 aa) initn: 6971 init1: 6971 opt: 6987 Z-score: 3464.5 bits: 653.9 E(32554): 1.2e-186 Smith-Waterman score: 6996; 89.1% identity (93.6% similar) in 1224 aa overlap (1-1205:81-1298) 10 20 30 pF1KSD MQTSEMDRKREAFLEHLKQKYPHHASAIMG :::::::::::::::::::::::::::::: CCDS31 NSRGSVSKSSRNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMG 60 70 80 90 100 110 40 50 60 70 80 90 pF1KSD HQERLRDQTRSPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HQERLRDQTRSPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASL 120 130 140 150 160 170 100 110 120 130 140 150 pF1KSD PVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESP 180 190 200 210 220 230 160 170 180 190 200 210 pF1KSD SVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYA 240 250 260 270 280 290 220 230 240 250 260 270 pF1KSD RGDGPGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 RGDGPGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 300 310 320 330 340 350 280 290 300 310 320 330 pF1KSD ISSLPVSRPISPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ISSLPVSRPISPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSH 360 370 380 390 400 410 340 350 360 370 380 390 pF1KSD GGHPLDVPDHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GGHPLDVPDHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKT 420 430 440 450 460 470 400 410 420 430 440 450 pF1KSD PPASPHRVSDLRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PPASPHRVSDLRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGL 480 490 500 510 520 530 460 470 480 490 500 510 pF1KSD SSLVDLGPPLMEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SSLVDLGPPLMEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYS 540 550 560 570 580 590 520 530 540 550 560 570 pF1KSD KDASSEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KDASSEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMR 600 610 620 630 640 650 580 590 600 610 620 630 pF1KSD RSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 RSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQE 660 670 680 690 700 710 640 650 660 670 680 690 pF1KSD RQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 RQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKG 720 730 740 750 760 770 700 710 720 730 740 750 pF1KSD EFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTD 780 790 800 810 820 830 760 770 780 790 800 810 pF1KSD AAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 AAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSS 840 850 860 870 880 890 820 830 840 850 860 870 pF1KSD PVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFI 900 910 920 930 940 950 880 890 900 910 920 930 pF1KSD EEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 EEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPA 960 970 980 990 1000 1010 940 950 960 970 980 990 pF1KSD TGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDV 1020 1030 1040 1050 1060 1070 1000 1010 1020 1030 1040 1050 pF1KSD VYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEG 1080 1090 1100 1110 1120 1130 1060 1070 1080 1090 1100 pF1KSD DKIMAELQGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSK---LQDPRQYRQA---NGSA ::::::::. . . : : : ... .:. :. :... :.. .. . .. CCDS31 DKIMAELQAFQ---KCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDV 1140 1150 1160 1170 1180 1110 1120 1130 1140 1150 pF1KSD KKSGGDFKPTSPSLPASKIP--ALSPSS------GKSSSLPSSSGDSSNLPNPPATKPSI .:: ... ..:.. .:. :. ::. : .:. :... .:. . : . CCDS31 RKSDVEYE-NGPQMEFQKVTTGAVRPSDPPKWERGMENSI-SDASRTSEYKTEIIMKENS 1190 1200 1210 1220 1230 1240 1160 1170 1180 1190 1200 1210 pF1KSD ASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLT-HTGKGHHLS---FS-PQSQNGRAPPP :: .: .: .:..: : .. : . .:: ..: .: :...: CCDS31 ISN-MSLLRDSRNYSQETVPKASFGFSGISPLEDEINKGSKISGLQYSIPDTENQTLNYG 1250 1260 1270 1280 1290 1300 1220 1230 1240 1250 1260 pF1KSD LSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS CCDS31 KTKEMEKQNTDKCHVSSHTRLTESSVHDFKTEDQEVITTDFGQVVLRPKEARHANVNPNE 1310 1320 1330 1340 1350 1360 >-- initn: 1451 init1: 1362 opt: 1362 Z-score: 685.2 bits: 139.6 E(32554): 7.6e-32 Smith-Waterman score: 1373; 50.2% identity (67.5% similar) in 520 aa overlap (756-1264:1472-1943) 730 740 750 760 770 780 pF1KSD RVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEEAA---HTSGQP . : ::. : . . ... ....: CCDS31 PVIIIFDEPMDIRSAYKRLSTIFEECDEELERMMMEEKIEEEEEEENGDSVVQNNNTSQM 1450 1460 1470 1480 1490 1500 790 800 810 820 830 pF1KSD FHSTGAPGDAKSEVVPLSGMMVR-HAQSSPVVIQPSQHSVALLNPAQ--NLPHVASSPAV :. :::. .. :..:. ..: .. . . . .: .. .. :: : . CCDS31 SHKKVAPGNLRT------GQQVETKSQPHSLATETRNPGGQEMNRTELNKFSHVDSPNSE 1510 1520 1530 1540 1550 840 850 860 870 880 890 pF1KSD PQEATSTLQMSQAPQSP---QIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEEKR . .: .. ..:.. ..: . : . :. ... :. : . . :.. . CCDS31 CKGEDATDDQFESPKKKFKFKFPKKQLAALTQAIRTGTKTGKKTLQVVVYEEEEEDGTLK 1560 1570 1580 1590 1600 1610 900 910 920 930 940 950 pF1KSD QNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPP--ATGPLPRGDAPVDKVELSEDSPNSE : : ..:.:: . . . ... :.: .:.:. : : .. . :: : CCDS31 Q---HKEAKRFEIARSQPEDTPENTVRRQEQPSIESTSPISRTDEIRKNTYRTLDS--LE 1620 1630 1640 1650 1660 1670 960 970 980 990 1000 1010 pF1KSD QDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQT : ...: . : : .. ...: : : ... ...:.: : CCDS31 QTIKQLENTISEMSPKA-----LVDTSCSSNR--DSV-------ASSSHIAQEASPRPLL 1680 1690 1700 1710 1020 1030 1040 1050 1060 1070 pF1KSD RATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVPMS : : :.. :: :.:. .:::::::::::::::: CCDS31 ----VPDEGPTAL---EPPTSIPSASR----------------KGSSGAPQTSRMPVPMS 1720 1730 1740 1750 1080 1090 1100 1110 1120 1130 pF1KSD AKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 AKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGKSS 1760 1770 1780 1790 1800 1810 1140 1150 1160 1170 1180 1190 pF1KSD SLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKG 1820 1830 1840 1850 1860 1870 1200 1210 1220 1230 1240 1250 pF1KSD HHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 HHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNGSSSK 1880 1890 1900 1910 1920 1930 1260 pF1KSD ATPSTAKETS :::::::::: CCDS31 ATPSTAKETS 1940 >>CCDS60505.1 KIAA1217 gene_id:56243|Hs108|chr10 (866 aa) initn: 3796 init1: 3796 opt: 3832 Z-score: 1910.8 bits: 365.2 E(32554): 4.1e-100 Smith-Waterman score: 5635; 96.1% identity (96.1% similar) in 897 aa overlap (203-1099:1-862) 180 190 200 210 220 230 pF1KSD IQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPN :::::::::::::::::::::::::::::: CCDS60 MQRELVYARGDGPGAPRPGSTAHPPHAIPN 10 20 30 240 250 260 270 280 290 pF1KSD SPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRD 40 50 60 70 80 90 300 310 320 330 340 350 pF1KSD VKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSA 100 110 120 130 140 150 360 370 380 390 400 410 pF1KSD SAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNA 160 170 180 190 200 210 420 430 440 450 460 470 pF1KSD HGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 HGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTAT 220 230 240 250 260 270 480 490 500 510 520 530 pF1KSD IPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMKTTANRNHTDSAG ::::::: :::::::::::::::::: CCDS60 IPKDRET-----------------------------------SEKMMKTTANRNHTDSAG 280 290 540 550 560 570 580 590 pF1KSD TPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQE 300 310 320 330 340 350 600 610 620 630 640 650 pF1KSD LLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFV 360 370 380 390 400 410 660 670 680 690 700 710 pF1KSD EDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRF 420 430 440 450 460 470 720 730 740 750 760 770 pF1KSD LKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQ 480 490 500 510 520 530 780 790 800 810 820 830 pF1KSD EEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPH 540 550 560 570 580 590 840 850 860 870 880 890 pF1KSD VASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKW 600 610 620 630 640 650 900 910 920 930 940 950 pF1KSD EEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPN 660 670 680 690 700 710 960 970 980 990 1000 1010 pF1KSD SEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSP 720 730 740 750 760 770 1020 1030 1040 1050 1060 1070 pF1KSD QTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 QTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQGSSGAPQTSRMPVP 780 790 800 810 820 830 1080 1090 1100 1110 1120 1130 pF1KSD MSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSSGK ::::::::::::::::::::::::::: CCDS60 MSAKNRPGTLDKPGKQSKLQDPRQYRQVVLP 840 850 860 >>CCDS60501.1 KIAA1217 gene_id:56243|Hs108|chr10 (1349 aa) initn: 4716 init1: 3512 opt: 3664 Z-score: 1825.0 bits: 350.0 E(32554): 2.5e-95 Smith-Waterman score: 7899; 94.2% identity (94.2% similar) in 1296 aa overlap (1-1256:81-1341) 10 20 30 pF1KSD MQTSEMDRKREAFLEHLKQKYPHHASAIMG :::::::::::::::::::::::::::::: CCDS60 NSRGSVSKSSRNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMG 60 70 80 90 100 110 40 50 60 70 80 90 pF1KSD HQERLRDQTRSPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 HQERLRDQTRSPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASL 120 130 140 150 160 170 100 110 120 130 140 150 pF1KSD PVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESP 180 190 200 210 220 230 160 170 180 190 200 210 pF1KSD SVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYA 240 250 260 270 280 290 220 230 240 250 260 270 pF1KSD RGDGPGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RGDGPGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 300 310 320 330 340 350 280 290 300 310 320 330 pF1KSD ISSLPVSRPISPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 ISSLPVSRPISPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSH 360 370 380 390 400 410 340 350 360 370 380 390 pF1KSD GGHPLDVPDHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GGHPLDVPDHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKT 420 430 440 450 460 470 400 410 420 430 440 450 pF1KSD PPASPHRVSDLRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PPASPHRVSDLRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGL 480 490 500 510 520 530 460 470 480 490 500 510 pF1KSD SSLVDLGPPLMEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYS ::::::::::::::::::::::::::::: CCDS60 SSLVDLGPPLMEKQVFAYSTATIPKDRET------------------------------- 540 550 520 530 540 550 560 570 pF1KSD KDASSEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 ----SEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMR 560 570 580 590 600 610 580 590 600 610 620 630 pF1KSD RSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQE 620 630 640 650 660 670 640 650 660 670 680 690 pF1KSD RQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKG 680 690 700 710 720 730 700 710 720 730 740 750 pF1KSD EFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTD 740 750 760 770 780 790 760 770 780 790 800 810 pF1KSD AAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 AAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSS 800 810 820 830 840 850 820 830 840 850 860 870 pF1KSD PVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFI 860 870 880 890 900 910 880 890 900 910 920 930 pF1KSD EEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPA 920 930 940 950 960 970 940 950 960 970 980 990 pF1KSD TGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDV 980 990 1000 1010 1020 1030 1000 1010 1020 1030 1040 1050 pF1KSD VYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEG 1040 1050 1060 1070 1080 1090 1060 1070 pF1KSD DKIMAELQ----------------------------------------GSSGAPQTSRMP :::::::: :::::::::::: CCDS60 DKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKKGSSGAPQTSRMP 1100 1110 1120 1130 1140 1150 1080 1090 1100 1110 1120 1130 pF1KSD VPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPALSPSS 1160 1170 1180 1190 1200 1210 1140 1150 1160 1170 1180 1190 pF1KSD GKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTH 1220 1230 1240 1250 1260 1270 1200 1210 1220 1230 1240 1250 pF1KSD TGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSVSLNQGAKGTRTIHTPSLTSYKAQNG 1280 1290 1300 1310 1320 1330 1260 pF1KSD SSSKATPSTAKETS :::::: CCDS60 SSSKATPSTAKETS 1340 >>CCDS60504.1 KIAA1217 gene_id:56243|Hs108|chr10 (932 aa) initn: 3512 init1: 3512 opt: 3571 Z-score: 1781.4 bits: 341.4 E(32554): 6.6e-93 Smith-Waterman score: 5493; 89.5% identity (89.5% similar) in 963 aa overlap (203-1099:1-928) 180 190 200 210 220 230 pF1KSD IQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYARGDGPGAPRPGSTAHPPHAIPN :::::::::::::::::::::::::::::: CCDS60 MQRELVYARGDGPGAPRPGSTAHPPHAIPN 10 20 30 240 250 260 270 280 290 pF1KSD SPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDRISSLPVSRPISPSPSAILERRD 40 50 60 70 80 90 300 310 320 330 340 350 pF1KSD VKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSA 100 110 120 130 140 150 360 370 380 390 400 410 pF1KSD SAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNA 160 170 180 190 200 210 420 430 440 450 460 470 pF1KSD HGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 HGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGLSSLVDLGPPLMEKQVFAYSTAT 220 230 240 250 260 270 480 490 500 510 520 530 pF1KSD IPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYSKDASSEKMMKTTANRNHTDSAG ::::::: :::::::::::::::::: CCDS60 IPKDRET-----------------------------------SEKMMKTTANRNHTDSAG 280 290 540 550 560 570 580 590 pF1KSD TPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQE 300 310 320 330 340 350 600 610 620 630 640 650 pF1KSD LLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFV 360 370 380 390 400 410 660 670 680 690 700 710 pF1KSD EDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRF 420 430 440 450 460 470 720 730 740 750 760 770 pF1KSD LKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 LKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQ 480 490 500 510 520 530 780 790 800 810 820 830 pF1KSD EEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPH 540 550 560 570 580 590 840 850 860 870 880 890 pF1KSD VASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKW 600 610 620 630 640 650 900 910 920 930 940 950 pF1KSD EEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPATGPLPRGDAPVDKVELSEDSPN 660 670 680 690 700 710 960 970 980 990 1000 1010 pF1KSD SEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVYTGRKENITAKASSEDAGPSP 720 730 740 750 760 770 1020 1030 1040 1050 pF1KSD QTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQ-------------- :::::::::::::::::::::::::::::::::::::::::::::: CCDS60 QTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQAFQKCSFMDVNSNS 780 790 800 810 820 830 1060 pF1KSD ----------------------------------------------------GSSGAPQT :::::::: CCDS60 HAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKSDVEYENGPQMEFQKGSSGAPQT 840 850 860 870 880 890 1070 1080 1090 1100 1110 1120 pF1KSD SRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSAKKSGGDFKPTSPSLPASKIPAL ::::::::::::::::::::::::::::::::: CCDS60 SRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQVVLP 900 910 920 930 1130 1140 1150 1160 1170 1180 pF1KSD SPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQTGPPAHSASLIPSVSNGSLKFQ >>CCDS60502.1 KIAA1217 gene_id:56243|Hs108|chr10 (1374 aa) initn: 4657 init1: 3262 opt: 3264 Z-score: 1627.2 bits: 313.4 E(32554): 2.6e-84 Smith-Waterman score: 7876; 92.3% identity (92.3% similar) in 1330 aa overlap (1-1264:81-1374) 10 20 30 pF1KSD MQTSEMDRKREAFLEHLKQKYPHHASAIMG :::::::::::::::::::::::::::::: CCDS60 NSRGSVSKSSRNIPRRHTLGGPRSSKEILGMQTSEMDRKREAFLEHLKQKYPHHASAIMG 60 70 80 90 100 110 40 50 60 70 80 90 pF1KSD HQERLRDQTRSPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 HQERLRDQTRSPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRGSRTRASL 120 130 140 150 160 170 100 110 120 130 140 150 pF1KSD PVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLTMKMLESP 180 190 200 210 220 230 160 170 180 190 200 210 pF1KSD SVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRMQRELVYA 240 250 260 270 280 290 220 230 240 250 260 270 pF1KSD RGDGPGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RGDGPGAPRPGSTAHPPHAIPNSPPSTPVPHSMPPSPSRIPYGGTRSMVVPGNATIPRDR 300 310 320 330 340 350 280 290 300 310 320 330 pF1KSD ISSLPVSRPISPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 ISSLPVSRPISPSPSAILERRDVKPDEDMSGKNIAMYRNEGFYADPYLYHEGRMSIASSH 360 370 380 390 400 410 340 350 360 370 380 390 pF1KSD GGHPLDVPDHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 GGHPLDVPDHIIAYHRTAIRSASAYCNPSMQAEMHMEQSLYRQKSRKYPDSHLPTLGSKT 420 430 440 450 460 470 400 410 420 430 440 450 pF1KSD PPASPHRVSDLRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PPASPHRVSDLRMIDMHAHYNAHGPPHTMQPDRASPSRQAFKKEPGTLVYIEKPRSAAGL 480 490 500 510 520 530 460 470 480 490 500 510 pF1KSD SSLVDLGPPLMEKQVFAYSTATIPKDRETRERMQAMEKQIASLTGLVQSALFKGPITSYS ::::::::::::::::::::::::::::: CCDS60 SSLVDLGPPLMEKQVFAYSTATIPKDRET------------------------------- 540 550 520 530 540 550 560 570 pF1KSD KDASSEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 ----SEKMMKTTANRNHTDSAGTPHVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMR 560 570 580 590 600 610 580 590 600 610 620 630 pF1KSD RSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RSVAELRLQLQQMRQLQLQNQELLRAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQE 620 630 640 650 660 670 640 650 660 670 680 690 pF1KSD RQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 RQKYLHEEEKIVKKLCELEDFVEDLKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKG 680 690 700 710 720 730 700 710 720 730 740 750 pF1KSD EFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EFPTLQNKMRAILRIEVEAVRFLKEEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTD 740 750 760 770 780 790 760 770 780 790 800 810 pF1KSD AAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 AAQAAQYMAMEKATAAEVLKSQEEAAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSS 800 810 820 830 840 850 820 830 840 850 860 870 pF1KSD PVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PVVIQPSQHSVALLNPAQNLPHVASSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFI 860 870 880 890 900 910 880 890 900 910 920 930 pF1KSD EEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 EEIHSVSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLLEEAQANIMKSIPNLEMPPA 920 930 940 950 960 970 940 950 960 970 980 990 pF1KSD TGPLPRGDAPVDKVELSEDSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDV ::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::: CCDS60 TGPLPRGDAPVDKVELS-DSPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDV 980 990 1000 1010 1020 1030 1000 1010 1020 1030 1040 1050 pF1KSD VYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VYTGRKENITAKASSEDAGPSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEG 1040 1050 1060 1070 1080 1090 pF1KSD DKIMAELQ---------------------------------------------------- :::::::: CCDS60 DKIMAELQAFQKCSFMDVNSNSHAEPSRADSHVKDTRSGATVPPKEKKNLEFFHEDVRKS 1100 1110 1120 1130 1140 1150 1060 1070 1080 1090 1100 pF1KSD --------------GSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSA :::::::::::::::::::::::::::::::::::::::::::::: CCDS60 DVEYENGPQMEFQKGSSGAPQTSRMPVPMSAKNRPGTLDKPGKQSKLQDPRQYRQANGSA 1160 1170 1180 1190 1200 1210 1110 1120 1130 1140 1150 1160 pF1KSD KKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 KKSGGDFKPTSPSLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQ 1220 1230 1240 1250 1260 1270 1170 1180 1190 1200 1210 1220 pF1KSD TGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 TGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASS 1280 1290 1300 1310 1320 1330 1230 1240 1250 1260 pF1KSD VSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS :::::::::::::::::::::::::::::::::::::::: CCDS60 VSLNQGAKGTRTIHTPSLTSYKAQNGSSSKATPSTAKETS 1340 1350 1360 1370 >>CCDS45660.1 SRCIN1 gene_id:80725|Hs108|chr17 (1183 aa) initn: 1921 init1: 651 opt: 1228 Z-score: 622.2 bits: 127.2 E(32554): 2.5e-28 Smith-Waterman score: 2316; 38.6% identity (64.9% similar) in 1201 aa overlap (1-1136:71-1181) 10 20 30 pF1KSD MQTSEMDRKREAFLEHLKQKYPHHASAIMG .: .. ::::.::..:::.:::.:: :. : CCDS45 GRRFSNVGLVHTSERRHTVIAAQSLEALSGLQKADADRKRDAFMDHLKSKYPQHALALRG 50 60 70 80 90 100 40 50 60 70 80 pF1KSD HQERLRDQ-------TRSPKLSHSPQPPSLGDPVEHLSETSADSLEAMSEGDAPTPFSRG .:.:.:.: ::: . ... :: .:.: . .:: .::.:::.:::.. : ::: CCDS45 QQDRMREQPNYWSFKTRSSRHTQGAQP-GLADQAAKLSYASAESLETMSEAELPLGFSRM 110 120 130 140 150 90 100 110 120 130 140 pF1KSD SRTRASLPVVRSTNQTKERSLGVLYLQYGDETKQLRMPNEITSADTIRALFVSAFPQQLT .: : :::. ::..::: :: :::.::.:.::..... .:..: ::..::.. :::.:: CCDS45 NRFRQSLPLSRSASQTKLRSPGVLFLQFGEETRRVHITHEVSSLDTLHALIAHMFPQKLT 160 170 180 190 200 210 150 160 170 180 190 200 pF1KSD MKMLESPSVAIYIKDESRNVYYELNDVRNIQDRSLLKVYNKDPAHAFNHTPKTMNGDMRM : ::.::..:: ::::.:::.:::.:::.:::::..:.: :.: .: . :::.: CCDS45 MGMLKSPNTAILIKDEARNVFYELEDVRDIQDRSIIKIYRKEPLYAAFPGSHLTNGDLR- 220 230 240 250 260 270 210 220 230 240 250 pF1KSD QRELVYARGDGPGAPRPGSTAHPPHAIPNSPPSTPVPHSMP-------PSPSRIPYGGTR ::.::: .. . : .. . :: .::: .: ..: :: ::. :.: : CCDS45 -REMVYASRESSPTRRLNNLSPAPHLASGSPPPG-LPSGLPSGLQSGSPSRSRLSYAGGR 280 290 300 310 320 330 260 270 280 290 300 310 pF1KSD SMVVPGNATIP----RDRISSLPVSRPISPSPSAILERRDVKPDEDMSGK--NIAMYRNE :. : : .:... :... .::::::::::::::::::...: .... ..: CCDS45 P---PSYAGSPVHHAAERLGGAPAAQGVSPSPSAILERRDVKPDEDLASKAGGMVLVKGE 340 350 360 370 380 390 320 330 340 350 360 pF1KSD GFYADPY-LYHEGRMSIASSHGGHPLDVPDHIIAYHRTAIRSASAYCNPSMQAEMHMEQS :.::::: : ::::.:.:.. .: :. : :.: ..:: :.: ..:.. .:.: CCDS45 GLYADPYGLLHEGRLSLAAA-AGDPFAYPGAGGLYKRGSVRSLSTYSAAALQSD--LEDS 400 410 420 430 440 450 370 380 390 400 410 420 pF1KSD LYRQKSRKYPDSHLPTLGSKTPPASPHRVSDLRMIDMHAHYNAHGPPHTMQ---PDRASP ::. . : . : . ::.::....:. : .. :::. :.:.:: CCDS45 LYKAAGGGGP-LYGDGYGFRLPPSSPQKLADVA-----APPGGPPPPHSPYSGPPSRGSP 460 470 480 490 500 430 440 450 460 470 pF1KSD SRQAFKKEPGTL-VYIEKP----RSAAGLSSL----VDLGPPLMEKQVFAYSTATIPKDR ::.:.:. :. :. :.: :::.. :. .: : :... ... . :: CCDS45 VRQSFRKDSGSSSVFAESPGGKTRSAGSASTAGAPPSELFPGPGERSLVGFGPPVPAKDT 510 520 530 540 550 560 480 490 500 510 520 530 pF1KSD ETRERMQAMEKQIASLTGLVQSALFKG--PITSYSK-DASSEKMMKTTANRNHTDSAGTP ::::::.:::::::::::::::::..: : : : ..:. .. . :.:. CCDS45 ETRERMEAMEKQIASLTGLVQSALLRGSEPETPSEKIEGSNGAATPSAPCGSGGRSSGAT 570 580 590 600 610 620 540 550 560 570 580 590 pF1KSD HVSGGKMLSALESTVPPSQPPPVGTSAIHMSLLEMRRSVAELRLQLQQMRQLQLQNQELL ::: :: :..: .:: :. ... : .. :...:: ::::.:.::::::: . CCDS45 PVSGPPPPSA--SSTPAGQPTAVSRLQMQLHLRGLQNSASDLRGQLQQLRKLQLQNQESV 630 640 650 660 670 680 600 610 620 630 640 650 pF1KSD RAMMKKAELEISGKVMETMKRLEDPVQRQRVLVEQERQKYLHEEEKIVKKLCELEDFVED ::..:..: :.: .: :. .: :::.::::.:::.:: .::..:: :...: .:: :: CCDS45 RALLKRTEAELSMRVSEAARRQEDPLQRQRTLVEEERLRYLNDEELITQQLNDLEKSVEK 690 700 710 720 730 740 660 670 680 690 700 710 pF1KSD LKKDSTAASRLVTLKDVEDGAFLLRQVGEAVATLKGEFPTLQNKMRAILRIEVEAVRFLK ...: . ::: ..:. :..:.:.::... ::..:: ::.:::..::.:::::.::: CCDS45 IQRDVSHNHRLVPGPELEEKALVLKQLGETLTELKAHFPGLQSKMRVVLRVEVEAVKFLK 750 760 770 780 790 800 720 730 740 750 760 770 pF1KSD EEPHKLDSLLKRVRSMTDVLTMLRRHVTDGLLKGTDAAQAAQYMAMEKATAAEVLKSQEE :::..::.:::: :..::.:...::.: .:. . : :: CCDS45 EEPQRLDGLLKRCRGVTDTLAQIRRQVDEGVWPPPNN-----------------LLSQSP 810 820 830 840 780 790 800 810 820 830 pF1KSD AAHTSGQPFHSTGAPGDAKSEVVPLSGMMVRHAQSSPVVIQPSQHSVALLNPAQNLPHVA :. :... . :. : :: : :: : CCDS45 KKVTAETDFNKS-----VDFEMPP-----------------PS--------PPLNL-HEL 850 860 870 840 850 860 870 880 890 pF1KSD SSPAVPQEATSTLQMSQAPQSPQIPMNGSAMQSLFIEEIHSVSAKNRAVSIEKAEKKWEE :.:: :..: : .:. ..: .:: ..:::.: ::. ::: CCDS45 SGPA---EGASLT-----------PKGGNPTKGLDTPGKRSV---DKAVSVEAAERDWEE 880 890 900 910 900 910 920 930 940 pF1KSD KRQNLDHYNGKEFEKLLEEAQANIMKSIPNLE-----MP-PATGP------LPRGDAPVD :: : .:..:....::::.::...:.::.:. : :: : :.:. . CCDS45 KRAALTQYSAKDINRLLEETQAELLKAIPDLDCASKAHPGPAPTPDHKPPKAPHGQKAAP 920 930 940 950 960 970 950 960 970 980 990 pF1KSD KVELSEDSPNSEQDLEKLGGKSPP--PPPPPPRRSYLPGSGLTTTRSGDVVYTGRKEN-I ..: : ..: . . ..: :::::::::. . ::::::.:.:: :..:.. . CCDS45 RTEPSGRRGSDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLTTTRTGEVVVTSKKDSAF 980 990 1000 1010 1020 1030 1000 1010 1020 1030 1040 1050 pF1KSD TAKASSEDAG-PSPQTRATKYPAEEPASAWTPSPPPVTTSSSKDEEEEEEEGDKIMAELQ :: ::. .::.. . .: : : ::. .:. :::..: :.:.:::. CCDS45 IKKAESEELEVQKPQVKLRRAVSE---VARPASTPPIMASAIKDEDDE----DRIIAELE 1040 1050 1060 1070 1080 1090 1060 1070 1080 1090 1100 1110 pF1KSD GSSGAPQTSRMPVP-----MSAKNRPGTLDKP--GKQ-SKLQDPRQYRQANGSAKKSGGD ...:. .. .: .:... :. :: ::: .. . . .::. .:. .:. CCDS45 SGGGSVPPMKVVTPGASRLKAAQGQAGSPDKSKHGKQRAEYMRIQAQQQATKPSKEMSGS 1100 1110 1120 1130 1140 1150 1120 1130 1140 1150 1160 pF1KSD FKPTSP-----SLPASKIPALSPSSGKSSSLPSSSGDSSNLPNPPATKPSIASNPLSPQT . .:: : ..::.:. ....::. CCDS45 NETSSPVSEKPSASRTSIPVLTSFGARNSSISF 1160 1170 1180 1170 1180 1190 1200 1210 1220 pF1KSD GPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFSSSPPSPASSV 1264 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:25:39 2016 done: Thu Nov 3 05:25:40 2016 Total Scan time: 4.090 Total Display time: 0.380 Function used was FASTA [36.3.4 Apr, 2011]