FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1227, 1066 aa 1>>>pF1KSDA1227 1066 - 1066 aa - 1066 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.4060+/-0.00118; mu= -8.0189+/- 0.070 mean_var=611.3377+/-159.605, 0's: 0 Z-trim(114.1): 50 B-trim: 804 in 1/53 Lambda= 0.051872 statistics sampled from 14654 (14695) to 14654 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.451), width: 16 Scan time: 5.610 The best scores are: opt bits E(32554) CCDS13678.1 ZBTB21 gene_id:49854|Hs108|chr21 (1066) 7189 554.2 5.4e-157 CCDS42934.1 ZBTB21 gene_id:49854|Hs108|chr21 ( 865) 3529 280.2 1.3e-74 >>CCDS13678.1 ZBTB21 gene_id:49854|Hs108|chr21 (1066 aa) initn: 7189 init1: 7189 opt: 7189 Z-score: 2932.0 bits: 554.2 E(32554): 5.4e-157 Smith-Waterman score: 7189; 100.0% identity (100.0% similar) in 1066 aa overlap (1-1066:1-1066) 10 20 30 40 50 60 pF1KSD MEGLLHYINPAHAISLLSALNEERLKGQLCDVLLIVGDQKFRAHKNVLAASSEYFQSLFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MEGLLHYINPAHAISLLSALNEERLKGQLCDVLLIVGDQKFRAHKNVLAASSEYFQSLFT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NKENESQTVFQLDFCEPDAFDNVLNYIYSSSLFVEKSSLAAVQELGYSLGISFLTNIVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NKENESQTVFQLDFCEPDAFDNVLNYIYSSSLFVEKSSLAAVQELGYSLGISFLTNIVSK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TPQAPFPTCPNRKKVFVEDDENSSQKRSVIVCQSRNEAQGKTVSQNQPDVSHTSRPSPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TPQAPFPTCPNRKKVFVEDDENSSQKRSVIVCQSRNEAQGKTVSQNQPDVSHTSRPSPSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AVKANTNKPHVPKPIEPLHNLSLTEKSWPKDSSVVYAKSLEHSGSLDDPNRISLVKRNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 AVKANTNKPHVPKPIEPLHNLSLTEKSWPKDSSVVYAKSLEHSGSLDDPNRISLVKRNAV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LPSKPLQDREAMDDKPGVSGQLPKGKALELALKRPRPPVLSVCSSSETPYLLKETNKGNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LPSKPLQDREAMDDKPGVSGQLPKGKALELALKRPRPPVLSVCSSSETPYLLKETNKGNG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QGEDRNLLYYSKLGLVIPSSGSGSGNQSIDRSGPLVKSLLRRSLSMDSQVPVYSPSIDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QGEDRNLLYYSKLGLVIPSSGSGSGNQSIDRSGPLVKSLLRRSLSMDSQVPVYSPSIDLK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SSQGSSSVSSDAPGNVLCALSQKSSLKDCSEKTALDDRPQVLQPHRLRSFSASQSTDREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SSQGSSSVSSDAPGNVLCALSQKSSLKDCSEKTALDDRPQVLQPHRLRSFSASQSTDREG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASPVTEVRIKTEPSSPLSDPSDIIRVTVGDAATTAAASSSSVTRDLSLKTEDDQKDMSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 ASPVTEVRIKTEPSSPLSDPSDIIRVTVGDAATTAAASSSSVTRDLSLKTEDDQKDMSRL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD PAKRRFQADRRLPFKKLKVNEHGSPVSEDNFEEGSSPTLLDADFPDSDLNKDEFGELEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PAKRRFQADRRLPFKKLKVNEHGSPVSEDNFEEGSSPTLLDADFPDSDLNKDEFGELEGT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RPNKKFKCKHCLKIFRSTAGLHRHVNMYHNPEKPYACDICHKRFHTNFKVWTHCQTQHGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 RPNKKFKCKHCLKIFRSTAGLHRHVNMYHNPEKPYACDICHKRFHTNFKVWTHCQTQHGI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD VKNPSPASSSHAVLDEKFQRKLIDIVREREIKKALIIKLRRGKPGFQGQSSSQAQQVIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VKNPSPASSSHAVLDEKFQRKLIDIVREREIKKALIIKLRRGKPGFQGQSSSQAQQVIKR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD NLRSRAKGAYICTYCGKAYRFLSQFKQHIKMHPGEKPLGVNKVAKPKEHAPLASPVENKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NLRSRAKGAYICTYCGKAYRFLSQFKQHIKMHPGEKPLGVNKVAKPKEHAPLASPVENKE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD VYQCRLCNAKLSSLLEQGSHERLCRNAAVCPYCSLRFFSPELKQEHESKCEYKKLTCLEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VYQCRLCNAKLSSLLEQGSHERLCRNAAVCPYCSLRFFSPELKQEHESKCEYKKLTCLEC 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD MRTFKSSFSIWRHQVEVHNQNNMAPTENFSLPVLDHNGDVTGSSRPQSQPEPNKVNHIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MRTFKSSFSIWRHQVEVHNQNNMAPTENFSLPVLDHNGDVTGSSRPQSQPEPNKVNHIVT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD TKDDNVFSDSSEQVNFDSEDSSCLPEDLSLSKQLKIQVKEEPVEEAEEEAPEASTAPKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TKDDNVFSDSSEQVNFDSEDSSCLPEDLSLSKQLKIQVKEEPVEEAEEEAPEASTAPKEA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD GPSKEASLWPCEKCGKMFTVHKQLERHQELLCSVKPFICHVCNKAFRTNFRLWSHFQSHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GPSKEASLWPCEKCGKMFTVHKQLERHQELLCSVKPFICHVCNKAFRTNFRLWSHFQSHM 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SQASEESAHKESEVCPVPTNSPSPPPLPPPPPLPKIQPLEPDSPTGLSENPTPATEKLFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SQASEESAHKESEVCPVPTNSPSPPPLPPPPPLPKIQPLEPDSPTGLSENPTPATEKLFV 970 980 990 1000 1010 1020 1030 1040 1050 1060 pF1KSD PQESDTLFYHAPPLSAITFKRQFMCKLCHRTFKTAFSLWSHEQTHN :::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PQESDTLFYHAPPLSAITFKRQFMCKLCHRTFKTAFSLWSHEQTHN 1030 1040 1050 1060 >>CCDS42934.1 ZBTB21 gene_id:49854|Hs108|chr21 (865 aa) initn: 3530 init1: 3465 opt: 3529 Z-score: 1452.8 bits: 280.2 E(32554): 1.3e-74 Smith-Waterman score: 5383; 81.1% identity (81.1% similar) in 1066 aa overlap (1-1066:1-865) 10 20 30 40 50 60 pF1KSD MEGLLHYINPAHAISLLSALNEERLKGQLCDVLLIVGDQKFRAHKNVLAASSEYFQSLFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MEGLLHYINPAHAISLLSALNEERLKGQLCDVLLIVGDQKFRAHKNVLAASSEYFQSLFT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD NKENESQTVFQLDFCEPDAFDNVLNYIYSSSLFVEKSSLAAVQELGYSLGISFLTNIVSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 NKENESQTVFQLDFCEPDAFDNVLNYIYSSSLFVEKSSLAAVQELGYSLGISFLTNIVSK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD TPQAPFPTCPNRKKVFVEDDENSSQKRSVIVCQSRNEAQGKTVSQNQPDVSHTSRPSPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TPQAPFPTCPNRKKVFVEDDENSSQKRSVIVCQSRNEAQGKTVSQNQPDVSHTSRPSPSI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD AVKANTNKPHVPKPIEPLHNLSLTEKSWPKDSSVVYAKSLEHSGSLDDPNRISLVKRNAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 AVKANTNKPHVPKPIEPLHNLSLTEKSWPKDSSVVYAKSLEHSGSLDDPNRISLVKRNAV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LPSKPLQDREAMDDKPGVSGQLPKGKALELALKRPRPPVLSVCSSSETPYLLKETNKGNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LPSKPLQDREAMDDKPGVSGQLPKGKALELALKRPRPPVLSVCSSSETPYLLKETNKGNG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD QGEDRNLLYYSKLGLVIPSSGSGSGNQSIDRSGPLVKSLLRRSLSMDSQVPVYSPSIDLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 QGEDRNLLYYSKLGLVIPSSGSGSGNQSIDRSGPLVKSLLRRSLSMDSQVPVYSPSIDLK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SSQGSSSVSSDAPGNVLCALSQKSSLKDCSEKTALDDRPQVLQPHRLRSFSASQSTDREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SSQGSSSVSSDAPGNVLCALSQKSSLKDCSEKTALDDRPQVLQPHRLRSFSASQSTDREG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ASPVTEVRIKTEPSSPLSDPSDIIRVTVGDAATTAAASSSSVTRDLSLKTEDDQKDMSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ASPVTEVRIKTEPSSPLSDPSDIIRVTVGDAATTAAASSSSVTRDLSLKTEDDQKDMSRL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD PAKRRFQADRRLPFKKLKVNEHGSPVSEDNFEEGSSPTLLDADFPDSDLNKDEFGELEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PAKRRFQADRRLPFKKLKVNEHGSPVSEDNFEEGSSPTLLDADFPDSDLNKDEF------ 490 500 510 520 530 550 560 570 580 590 600 pF1KSD RPNKKFKCKHCLKIFRSTAGLHRHVNMYHNPEKPYACDICHKRFHTNFKVWTHCQTQHGI CCDS42 ------------------------------------------------------------ 610 620 630 640 650 660 pF1KSD VKNPSPASSSHAVLDEKFQRKLIDIVREREIKKALIIKLRRGKPGFQGQSSSQAQQVIKR CCDS42 ------------------------------------------------------------ 670 680 690 700 710 720 pF1KSD NLRSRAKGAYICTYCGKAYRFLSQFKQHIKMHPGEKPLGVNKVAKPKEHAPLASPVENKE CCDS42 ------------------------------------------------------------ 730 740 750 760 770 780 pF1KSD VYQCRLCNAKLSSLLEQGSHERLCRNAAVCPYCSLRFFSPELKQEHESKCEYKKLTCLEC ::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ---------------EQGSHERLCRNAAVCPYCSLRFFSPELKQEHESKCEYKKLTCLEC 540 550 560 570 790 800 810 820 830 840 pF1KSD MRTFKSSFSIWRHQVEVHNQNNMAPTENFSLPVLDHNGDVTGSSRPQSQPEPNKVNHIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MRTFKSSFSIWRHQVEVHNQNNMAPTENFSLPVLDHNGDVTGSSRPQSQPEPNKVNHIVT 580 590 600 610 620 630 850 860 870 880 890 900 pF1KSD TKDDNVFSDSSEQVNFDSEDSSCLPEDLSLSKQLKIQVKEEPVEEAEEEAPEASTAPKEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TKDDNVFSDSSEQVNFDSEDSSCLPEDLSLSKQLKIQVKEEPVEEAEEEAPEASTAPKEA 640 650 660 670 680 690 910 920 930 940 950 960 pF1KSD GPSKEASLWPCEKCGKMFTVHKQLERHQELLCSVKPFICHVCNKAFRTNFRLWSHFQSHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GPSKEASLWPCEKCGKMFTVHKQLERHQELLCSVKPFICHVCNKAFRTNFRLWSHFQSHM 700 710 720 730 740 750 970 980 990 1000 1010 1020 pF1KSD SQASEESAHKESEVCPVPTNSPSPPPLPPPPPLPKIQPLEPDSPTGLSENPTPATEKLFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SQASEESAHKESEVCPVPTNSPSPPPLPPPPPLPKIQPLEPDSPTGLSENPTPATEKLFV 760 770 780 790 800 810 1030 1040 1050 1060 pF1KSD PQESDTLFYHAPPLSAITFKRQFMCKLCHRTFKTAFSLWSHEQTHN :::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PQESDTLFYHAPPLSAITFKRQFMCKLCHRTFKTAFSLWSHEQTHN 820 830 840 850 860 1066 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:28:39 2016 done: Thu Nov 3 05:28:40 2016 Total Scan time: 5.610 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]