Result of FASTA (omim) for
pF1KSDA1234
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1234, 719 aa
1>>>pF1KSDA1234 719 - 719 aa - 719 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9984+/-0.000378; mu= 3.4634+/- 0.023
mean_var=246.5519+/-52.805, 0's: 0 Z-trim(120.8): 52 B-trim: 450 in 1/55
Lambda= 0.081681
statistics sampled from 36554 (36617) to 36554 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.756), E-opt: 0.2 (0.429), width: 16
Scan time: 13.330
The best scores are: opt bits E(85289)
NP_065782 (OMIM: 606517) aryl hydrocarbon receptor ( 719) 5037 607.2 7.2e-173
NP_001229341 (OMIM: 606517) aryl hydrocarbon recep ( 701) 3273 399.3 2.6e-110
NP_001612 (OMIM: 600253) aryl hydrocarbon receptor ( 848) 840 112.7 6.2e-24
XP_016882332 (OMIM: 603346) PREDICTED: neuronal PA ( 582) 327 52.1 7.4e-06
XP_016882330 (OMIM: 603346) PREDICTED: neuronal PA ( 651) 325 51.9 9.4e-06
XP_011525309 (OMIM: 603346) PREDICTED: neuronal PA ( 411) 318 50.9 1.2e-05
XP_011525308 (OMIM: 603346) PREDICTED: neuronal PA ( 411) 318 50.9 1.2e-05
XP_011525304 (OMIM: 603346) PREDICTED: neuronal PA ( 454) 318 50.9 1.3e-05
XP_006723294 (OMIM: 603346) PREDICTED: neuronal PA ( 410) 317 50.8 1.3e-05
XP_016882331 (OMIM: 603346) PREDICTED: neuronal PA ( 650) 320 51.3 1.4e-05
XP_011525301 (OMIM: 603346) PREDICTED: neuronal PA ( 580) 318 51.0 1.5e-05
XP_011525299 (OMIM: 603346) PREDICTED: neuronal PA ( 591) 318 51.0 1.6e-05
NP_002508 (OMIM: 603346) neuronal PAS domain-conta ( 590) 317 50.9 1.7e-05
XP_011525303 (OMIM: 603346) PREDICTED: neuronal PA ( 483) 315 50.6 1.7e-05
XP_016883931 (OMIM: 600892) PREDICTED: single-mind ( 327) 299 48.6 4.8e-05
NP_033664 (OMIM: 600892) single-minded homolog 2 s ( 570) 299 48.8 7.2e-05
NP_005060 (OMIM: 600892) single-minded homolog 2 l ( 667) 299 48.9 8e-05
XP_011534374 (OMIM: 601665,603128) PREDICTED: sing ( 481) 272 45.5 0.00057
NP_005059 (OMIM: 601665,603128) single-minded homo ( 766) 272 45.7 0.00081
XP_005267157 (OMIM: 601665,603128) PREDICTED: sing ( 766) 272 45.7 0.00081
XP_016866686 (OMIM: 601665,603128) PREDICTED: sing ( 766) 272 45.7 0.00081
>>NP_065782 (OMIM: 606517) aryl hydrocarbon receptor rep (719 aa)
initn: 5037 init1: 5037 opt: 5037 Z-score: 3224.6 bits: 607.2 E(85289): 7.2e-173
Smith-Waterman score: 5037; 99.9% identity (99.9% similar) in 719 aa overlap (1-719:1-719)
10 20 30 40 50 60
pF1KSD MPRTMIPPGECTYAGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MPRTMIPPGECTYAGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLEGRLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 IISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLEGRLLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD PPQVVFGQAPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFL
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PPQVVFGQPPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ARGSQAWQLRLCCPEPLMTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ARGSQAWQLRLCCPEPLMTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD AEMKMRSALLRAKPRADTAATADAKVKATTSLCESELHGKPNYSAGRSSRESGVLVLREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AEMKMRSALLRAKPRADTAATADAKVKATTSLCESELHGKPNYSAGRSSRESGVLVLREQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGDREEEQHRMLSRASGVTGRRETPGPTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGDREEEQHRMLSRASGVTGRRETPGPTK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PLPWTAGKHSEDGARPRLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNSPISHPPSPSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PLPWTAGKHSEDGARPRLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNSPISHPPSPSPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD AYSSRTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYPMEDMKLQGVPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AYSSRTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYPMEDMKLQGVPMP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD PGDLCGPTLLLDVSIKMEKDSGCEGAADGCVPSQVWLGASDRSHPATFPTRMHLKTEPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PGDLCGPTLLLDVSIKMEKDSGCEGAADGCVPSQVWLGASDRSHPATFPTRMHLKTEPDS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD RQQVYISHLGHGVRGAQPHGRATAGRSRELTPFHPAHCACLEPTDGLPQSEPPHQLCARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RQQVYISHLGHGVRGAQPHGRATAGRSRELTPFHPAHCACLEPTDGLPQSEPPHQLCARG
610 620 630 640 650 660
670 680 690 700 710
pF1KSD RGEQSCTCRAAEAAPVVKREPLDSPQWATHSQGMVPGMLPKSALATLVPPQASGCTFLP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RGEQSCTCRAAEAAPVVKREPLDSPQWATHSQGMVPGMLPKSALATLVPPQASGCTFLP
670 680 690 700 710
>>NP_001229341 (OMIM: 606517) aryl hydrocarbon receptor (701 aa)
initn: 3273 init1: 3273 opt: 3273 Z-score: 2101.3 bits: 399.3 E(85289): 2.6e-110
Smith-Waterman score: 4851; 97.4% identity (97.4% similar) in 719 aa overlap (1-719:1-701)
10 20 30 40 50 60
pF1KSD MPRTMIPPGECTYAGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRTMIPPGECTYAGRKRRRPLQKQRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPPD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD IISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLEGRLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLAGSAVLEGRLLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD PPQVVFGQAPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFL
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPQVVFGQPPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLLDSTSGFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ARGSQAWQLRLCCPEPLMTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSA
::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------TMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSA
250 260 270 280
310 320 330 340 350 360
pF1KSD AEMKMRSALLRAKPRADTAATADAKVKATTSLCESELHGKPNYSAGRSSRESGVLVLREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEMKMRSALLRAKPRADTAATADAKVKATTSLCESELHGKPNYSAGRSSRESGVLVLREQ
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD TDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGDREEEQHRMLSRASGVTGRRETPGPTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGDREEEQHRMLSRASGVTGRRETPGPTK
350 360 370 380 390 400
430 440 450 460 470 480
pF1KSD PLPWTAGKHSEDGARPRLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNSPISHPPSPSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLPWTAGKHSEDGARPRLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNSPISHPPSPSPS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD AYSSRTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYPMEDMKLQGVPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYSSRTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYPMEDMKLQGVPMP
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD PGDLCGPTLLLDVSIKMEKDSGCEGAADGCVPSQVWLGASDRSHPATFPTRMHLKTEPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGDLCGPTLLLDVSIKMEKDSGCEGAADGCVPSQVWLGASDRSHPATFPTRMHLKTEPDS
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD RQQVYISHLGHGVRGAQPHGRATAGRSRELTPFHPAHCACLEPTDGLPQSEPPHQLCARG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQQVYISHLGHGVRGAQPHGRATAGRSRELTPFHPAHCACLEPTDGLPQSEPPHQLCARG
590 600 610 620 630 640
670 680 690 700 710
pF1KSD RGEQSCTCRAAEAAPVVKREPLDSPQWATHSQGMVPGMLPKSALATLVPPQASGCTFLP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGEQSCTCRAAEAAPVVKREPLDSPQWATHSQGMVPGMLPKSALATLVPPQASGCTFLP
650 660 670 680 690 700
>>NP_001612 (OMIM: 600253) aryl hydrocarbon receptor [Ho (848 aa)
initn: 1089 init1: 608 opt: 840 Z-score: 550.7 bits: 112.7 E(85289): 6.2e-24
Smith-Waterman score: 1026; 42.1% identity (62.9% similar) in 475 aa overlap (12-448:9-456)
10 20 30 40 50
pF1KSD MPRTMIPPGECTYAGRKRRRPLQKQRPAVGAE--KSNPSKRHRDRLNAELDHLASLLPFP
:::.::::.:.:: . :: :::::::::::::.:::.::::::::
NP_001 MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFP
10 20 30 40 50
60 70 80 90 100 110
pF1KSD PDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPGDSCPLA----GSAVL
:.:.::::::::::::::::.::::.:. ..: . .: :.: : : .
NP_001 QDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQ----DNCRAANFREGLNLQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KSD EGRLLLESLNGFALVVSAEGTIFYASATIVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQ
::..::..::::.:::.... .::::.:: :::::.:.::.::..:. ::..:: .: ::
NP_001 EGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD LHWAMDPPQVVF-GQAPPLETGDDAILGRLLRAQEWGTGTPTEYSAFLTRCFICRVRCLL
::::..: : . ::. :: : . . . : : : .. ::::::.::::
NP_001 LHWALNPSQCTESGQGIEEATG----LPQTVVCYN-PDQIPPENSPLMERCFICRLRCLL
180 190 200 210 220
240 250 260 270 280 290
pF1KSD DSTSGFLARGSQAWQLRLCCPEPLMTMQFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAA
:..::::: :.::::::.: :::::. .:..:::.:.:: ::.
NP_001 DNSSGFLA------------------MNFQGKLKYLHGQKKKGKDGSILPPQLALFAIAT
230 240 250 260 270
300 310 320 330 340
pF1KSD PVLLPSAAEMKMRSALLRAKPRAD-TAATADAKVKATTSLCESELHGKPN----------
:. :: :.. .. ..:.: . : : ::: . . . :.:: . .
NP_001 PLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGRIVLGYTEAELCTRGSGYQFIHAADM
280 290 300 310 320 330
350 360 370 380 390
pF1KSD -YSAGRSSR-----ESGVLVLREQTDAGRWAQVPARAPCLCLRGGPDLVLDPKGGSGDRE
: : : :::..:.: : .::. : . : : : :: .. . :.:
NP_001 LYCAESHIRMIKTGESGMIVFRLLTKNNRWTWVQSNARLLYKNGRPDYIIVTQRPLTDEE
340 350 360 370 380 390
400 410 420 430 440
pF1KSD EEQHR---------MLSRASGVTGRRETPGPT--KPLPWTA--GKHSEDGARPR-LQPSK
.: :.. . .: . .: :. ::: . : ..:.: :. ..
NP_001 GTEHLRKRNTKLPFMFTTGEAVLYEATNPFPAIMDPLPLRTKNGTSGKDSATTSTLSKDS
400 410 420 430 440 450
450 460 470 480 490 500
pF1KSD NDPPSLRPMPRGSCLPCPCVQGTFRNSPISHPPSPSPSAYSSRTSRPMRDVGEDQVHPPL
.: ::
NP_001 LNPSSLLAAMMQQDESIYLYPASSTSSTAPFENNFFNESMNECRNWQDNTAPMGNDTILK
460 470 480 490 500 510
>>XP_016882332 (OMIM: 603346) PREDICTED: neuronal PAS do (582 aa)
initn: 291 init1: 150 opt: 327 Z-score: 226.2 bits: 52.1 E(85289): 7.4e-06
Smith-Waterman score: 349; 25.6% identity (50.3% similar) in 587 aa overlap (1-541:29-564)
10 20 30
pF1KSD MPRTMI--PPGECTYAGRKRRRPLQKQRPAVG
.: :. : : : : :: .:.:
XP_016 MAAPYPGSGGGSEVKCVGGRGASVPWDFLPGLMVKAPSGPCLQAQRK-----EKSR----
10 20 30 40 50
40 50 60 70 80 90
pF1KSD AEKSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQ
: .. .: . : :. .::.:::.: : :.::: :..::::.:::.. : .
XP_016 ----NAARSRRGKENLEFFELAKLLPLPGAISSQLDKASIVRLSVTYLRLRRFAALGAPP
60 70 80 90 100
100 110 120 130 140
pF1KSD SSRQPAAGAPS---PGDSCPLAG-SAVLEGRL---LLESLNGFALVVSAEGTIFYASATI
. . ::: :. :: : : : :.: .: .:.::.::..... :: ..: : :.
XP_016 WGLR-AAGPPAGLAPGRRGPAALVSEVFEQHLGGHILQSLDGFVFALNQEGKFLYISETV
110 120 130 140 150 160
150 160 170 180 190 200
pF1KSD VDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQAPPLETGDDAILGRL
:::. :... ....:::: :... .:: : .:: ..... . :
XP_016 SIYLGLSQVEMTGSSVFDYIHPGDHSEVLEQLGLRTPTPG---PPTPPSVSSSSSSSSSL
170 180 190 200 210 220
210 220 230 240 250 260
pF1KSD LRAQEW-GTGTPTEYSAFLT-RCFICRVRCLLDSTSGFLARGSQAWQLRLCCPEPLMTMQ
. : .. : . :... : :. :.. : . :. ...: :. ..
XP_016 ADTPEIEASLTKVPPSSLVQERSFFVRMKSTL-TKRGLHVKASGYKQV----------IH
230 240 250 260 270
270 280 290 300
pF1KSD FQGKLK------FLFGQK-KKAP------SGAMLPPRLSLFCIAAPVLLPSAAEMKMRSA
:.:. .:. :: : :. :::: . .: . .
XP_016 VTGRLRAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPS
280 290 300 310 320 330
310 320 330 340 350 360
pF1KSD LLRAKPRADTAATADA-KVKATTSLCESELHGKPNYSAGRSSRESGVLVLREQTDAGRWA
: .. . . :: ... . ::..:: :. . ..: : :: . ..
XP_016 ELVGRSCYQFVHGQDATRIRQSHVDCETHLH-PPSLPTTPQTRASHSLV--PGSPSSGLP
340 350 360 370 380
370 380 390 400
pF1KSD QVPARAPCLCLRGGPDLV------LDPKGGSGDREEEQ---HRMLSRASG---------V
:: :: : : . :. .: :. . . .: :.::.: :
XP_016 TVPPAAPT--APGTPFSIGRAARRLSDASGLLDKGQVMTGYYRWLQRAGGFVWLQSVATV
390 400 410 420 430 440
410 420 430 440 450 460
pF1KSD TGRRETPGPTKPLPWTAG--KHSEDGARPRLQPSKNDPPSLRPMPRGSCLPCPCVQGTFR
.: ..:: . : :.. ...: : : . . : :. .: : : ..: .
XP_016 AGSGKSPGEHHVL-WVSHVLSQAEGGQTP--LDAFQLPASVACEEASSPGPEP-TDG--K
450 460 470 480 490 500
470 480 490 500 510 520
pF1KSD NSPISHPPSPSPSAYSSRTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFA-TRG
. .: . : ..::. .: : ..::: . :. .:.... .::
XP_016 TEGWGHTQALSIFLFQSRS---LRRKGS--------RLPQRRTRPPRPRANASKWSPARG
510 520 530 540 550
530 540 550 560 570 580
pF1KSD YPMEDMKLQGVPMPPGDLCGPTLLLDVSIKMEKDSGCEGAADGCVPSQVWLGASDRSHPA
: . . .. .::
XP_016 KP-KAPRTVATRIPPATRPHRGPSSPLSSGQGS
560 570 580
>>XP_016882330 (OMIM: 603346) PREDICTED: neuronal PAS do (651 aa)
initn: 304 init1: 150 opt: 325 Z-score: 224.2 bits: 51.9 E(85289): 9.4e-06
Smith-Waterman score: 353; 26.0% identity (48.7% similar) in 599 aa overlap (1-550:29-585)
10 20 30
pF1KSD MPRTMI--PPGECTYAGRKRRRPLQKQRPAVG
.: :. : : : : :: .:.:
XP_016 MAAPYPGSGGGSEVKCVGGRGASVPWDFLPGLMVKAPSGPCLQAQRK-----EKSR----
10 20 30 40 50
40 50 60 70 80
pF1KSD AEKSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQV-VQE
: .. .: . : :. .::.:::.: : :.::: :..::::.:::.. : . .
XP_016 ----NAARSRRGKENLEFFELAKLLPLPGAISSQLDKASIVRLSVTYLRLRRFAALGAPP
60 70 80 90 100
90 100 110 120 130 140
pF1KSD QSSRQPAAGAPS---PGDSCPLAG-SAVLEGRL---LLESLNGFALVVSAEGTIFYASAT
. : ::: :. :: : : : :.: .: .:.::.::..... :: ..: : :
XP_016 WGLR--AAGPPAGLAPGRRGPAALVSEVFEQHLGGHILQSLDGFVFALNQEGKFLYISET
110 120 130 140 150 160
150 160 170 180 190 200
pF1KSD IVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQAPPLETGDDAILGR
. :::. :... ....:::: :... .:: : .:: ..... .
XP_016 VSIYLGLSQVEMTGSSVFDYIHPGDHSEVLEQLGLRTPTPG---PPTPPSVSSSSSSSSS
170 180 190 200 210 220
210 220 230 240 250 260
pF1KSD LLRAQEW-GTGTPTEYSAFLT-RCFICRVRCLLDSTSGFLARGSQAWQLRLCCPEPLMTM
: . : .. : . :... : :. :.. : . :. ...: :. . .
XP_016 LADTPEIEASLTKVPPSSLVQERSFFVRMKSTL-TKRGLHVKASGYKQVIHVTGR--LRA
230 240 250 260 270
270 280 290 300 310
pF1KSD QFQGKLKFLFGQKKKAP------SGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKP
. : : : :: : :. :::: . .: . . : ..
XP_016 HALG-LVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRS
280 290 300 310 320 330
320 330 340 350 360 370
pF1KSD RADTAATADA-KVKATTSLCESELHGKPNYSAGRSSRESGVLVLREQTDAGRWAQVPARA
. . :: ... . ::..:: :. . ..: : :: . .. :: :
XP_016 CYQFVHGQDATRIRQSHVDCETHLH-PPSLPTTPQTRASHSLV--PGSPSSGLPTVPPAA
340 350 360 370 380 390
380 390 400 410
pF1KSD PCLCLRGGPDLV------LDPKGGSGDREEEQ---HRMLSRASG---------VTGRRET
: : : . :. .: :. . . .: :.::.: :.: ..
XP_016 PT--APGTPFSIGRAARRLSDASGLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKS
400 410 420 430 440 450
420 430 440 450 460
pF1KSD PGPTKPLPWTAG--KHSEDGARP----RLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNS
:: . : :.. ...: : : .: : . : :. . : : ..: . .
XP_016 PGEHHVL-WVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTE-PEPPTEGK-QAA
460 470 480 490 500 510
470 480 490 500 510 520
pF1KSD PISHPPSPSPSAY-----SSRTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFAT
: . . . . : .. .: :... : : : :.:
XP_016 PAENEAPQTQGKRIKVEPGPRETKGSEDSGDED---PSSH-PAT------PRPEFTSVIR
520 530 540 550 560
530 540 550 560 570 580
pF1KSD RGYPMED-MKLQGVPMPPGDLCGPTLLLDVSIKMEKDSGCEGAADGCVPSQVWLGASDRS
: .: .. :. :::: ::::
XP_016 AGVLKQDPVRPWGLA-PPGDP-PPTLLHAGFLPPVVRGLCTPGTIRYGPAELGLVYPHLQ
570 580 590 600 610
>>XP_011525309 (OMIM: 603346) PREDICTED: neuronal PAS do (411 aa)
initn: 290 init1: 150 opt: 318 Z-score: 222.4 bits: 50.9 E(85289): 1.2e-05
Smith-Waterman score: 318; 31.4% identity (58.2% similar) in 261 aa overlap (1-249:29-270)
10 20 30
pF1KSD MPRTMI--PPGECTYAGRKRRRPLQKQRPAVG
.: :. : : : : :: .:.:
XP_011 MAAPYPGSGGGSEVKCVGGRGASVPWDFLPGLMVKAPSGPCLQAQRK-----EKSR----
10 20 30 40 50
40 50 60 70 80
pF1KSD AEKSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQV-VQE
: .. .: . : :. .::.:::.: : :.::: :..::::.:::.. : . .
XP_011 ----NAARSRRGKENLEFFELAKLLPLPGAISSQLDKASIVRLSVTYLRLRRFAALGAPP
60 70 80 90 100
90 100 110 120 130 140
pF1KSD QSSRQPAAGAPS---PGDSCPLAG-SAVLEGRL---LLESLNGFALVVSAEGTIFYASAT
. : ::: :. :: : : : :.: .: .:.::.::..... :: ..: : :
XP_011 WGLR--AAGPPAGLAPGRRGPAALVSEVFEQHLGGHILQSLDGFVFALNQEGKFLYISET
110 120 130 140 150 160
150 160 170 180 190 200
pF1KSD IVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQAPPLETGDDAILGR
. :::. :... ....:::: :... .:: : .:: ..... .
XP_011 VSIYLGLSQVEMTGSSVFDYIHPGDHSEVLEQLGLRTPTPG---PPTPPSVSSSSSSSSS
170 180 190 200 210 220
210 220 230 240 250 260
pF1KSD LLRAQEW-GTGTPTEYSAFLT-RCFICRVRCLLDSTSGFLARGSQAWQLRLCCPEPLMTM
: . : .. : . :... : :. :.. : . :. ...: :.
XP_011 LADTPEIEASLTKVPPSSLVQERSFFVRMKSTL-TKRGLHVKASGYKQVIHVTGRLRAHA
230 240 250 260 270 280
270 280 290 300 310 320
pF1KSD QFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRADTAA
XP_011 LGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQ
290 300 310 320 330 340
>>XP_011525308 (OMIM: 603346) PREDICTED: neuronal PAS do (411 aa)
initn: 290 init1: 150 opt: 318 Z-score: 222.4 bits: 50.9 E(85289): 1.2e-05
Smith-Waterman score: 318; 31.4% identity (58.2% similar) in 261 aa overlap (1-249:29-270)
10 20 30
pF1KSD MPRTMI--PPGECTYAGRKRRRPLQKQRPAVG
.: :. : : : : :: .:.:
XP_011 MAAPYPGSGGGSEVKCVGGRGASVPWDFLPGLMVKAPSGPCLQAQRK-----EKSR----
10 20 30 40 50
40 50 60 70 80
pF1KSD AEKSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQV-VQE
: .. .: . : :. .::.:::.: : :.::: :..::::.:::.. : . .
XP_011 ----NAARSRRGKENLEFFELAKLLPLPGAISSQLDKASIVRLSVTYLRLRRFAALGAPP
60 70 80 90 100
90 100 110 120 130 140
pF1KSD QSSRQPAAGAPS---PGDSCPLAG-SAVLEGRL---LLESLNGFALVVSAEGTIFYASAT
. : ::: :. :: : : : :.: .: .:.::.::..... :: ..: : :
XP_011 WGLR--AAGPPAGLAPGRRGPAALVSEVFEQHLGGHILQSLDGFVFALNQEGKFLYISET
110 120 130 140 150 160
150 160 170 180 190 200
pF1KSD IVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQAPPLETGDDAILGR
. :::. :... ....:::: :... .:: : .:: ..... .
XP_011 VSIYLGLSQVEMTGSSVFDYIHPGDHSEVLEQLGLRTPTPG---PPTPPSVSSSSSSSSS
170 180 190 200 210 220
210 220 230 240 250 260
pF1KSD LLRAQEW-GTGTPTEYSAFLT-RCFICRVRCLLDSTSGFLARGSQAWQLRLCCPEPLMTM
: . : .. : . :... : :. :.. : . :. ...: :.
XP_011 LADTPEIEASLTKVPPSSLVQERSFFVRMKSTL-TKRGLHVKASGYKQVIHVTGRLRAHA
230 240 250 260 270 280
270 280 290 300 310 320
pF1KSD QFQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRADTAA
XP_011 LGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQ
290 300 310 320 330 340
>>XP_011525304 (OMIM: 603346) PREDICTED: neuronal PAS do (454 aa)
initn: 264 init1: 150 opt: 318 Z-score: 221.8 bits: 50.9 E(85289): 1.3e-05
Smith-Waterman score: 344; 27.0% identity (51.0% similar) in 486 aa overlap (1-465:29-454)
10 20 30
pF1KSD MPRTMI--PPGECTYAGRKRRRPLQKQRPAVG
.: :. : : : : :: .:.:
XP_011 MAAPYPGSGGGSEVKCVGGRGASVPWDFLPGLMVKAPSGPCLQAQRK-----EKSR----
10 20 30 40 50
40 50 60 70 80 90
pF1KSD AEKSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQ
: .. .: . : :. .::.:::.: : :.::: :..::::.:::.. : .
XP_011 ----NAARSRRGKENLEFFELAKLLPLPGAISSQLDKASIVRLSVTYLRLRRFAALGAPP
60 70 80 90 100
100 110 120 130 140
pF1KSD SSRQPAAGAPS---PGDSCPLAG-SAVLEGRL---LLESLNGFALVVSAEGTIFYASATI
. . ::: :. :: : : : :.: .: .:.::.::..... :: ..: : :.
XP_011 WGLR-AAGPPAGLAPGRRGPAALVSEVFEQHLGGHILQSLDGFVFALNQEGKFLYISETV
110 120 130 140 150 160
150 160 170 180 190 200
pF1KSD VDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQAPPLETGDDAILGRL
:::. :... ....:::: :... .:: : .:: ..... . :
XP_011 SIYLGLSQVEMTGSSVFDYIHPGDHSEVLEQLGLRTPTPG---PPTPPSVSSSSSSSSSL
170 180 190 200 210 220
210 220 230 240 250 260
pF1KSD LRAQEW-GTGTPTEYSAFLT-RCFICRVRCLLDSTSGFLARGSQAWQLRLCCPEPLMTMQ
. : .. : . :... : :. :.. : . :. ...: :. ..
XP_011 ADTPEIEASLTKVPPSSLVQERSFFVRMKSTL-TKRGLHVKASGYKQV----------IH
230 240 250 260 270
270 280 290 300 310 320
pF1KSD FQGKLK-FLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRADTAA
:.:. .: . : ::: ::. ::. ... .. . .
XP_011 VTGRLRAHALGL---VALGHTLPP--------APL-----AELPLHGHMIVFRLSLGLTI
280 290 300 310
330 340 350 360 370
pF1KSD TA-DAKVKATTSLCESELHGKPNYS--AGRSS---RESGVLVLREQTDAGRWAQVPAR-A
: ...:. .: ::: :. :. :... :.: : . ... .:.
XP_011 LACESRVSDHMDLGPSELVGRSCYQFVHGQDATRIRQSHV---DSKPRVAKLLWMPSSFQ
320 330 340 350 360 370
380 390 400 410 420 430
pF1KSD PCLCLRGGPDLVLDPKGGSGDREEEQHRMLSRASGVTGRRETPGPTKPLPWTAGKHSEDG
: .: : .: : : : : : .. .:.: : .: .:.: :
XP_011 PAWPVRRHP-----ARGQS-----PQSRSLRRKGSRLPQRRTR-PPRPRA-NASKWSPAR
380 390 400 410 420
440 450 460 470 480 490
pF1KSD ARPRLQPSKND--PPSLRPMPRGSCLPCPCVQGTFRNSPISHPPSPSPSAYSSRTSRPMR
..:. . ::. :: :: : ::.
XP_011 GKPKAPRTVATRIPPATRPH-RGPSSPLSSGQGS
430 440 450
500 510 520 530 540 550
pF1KSD DVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFATRGYPMEDMKLQGVPMPPGDLCGPTLLL
>>XP_006723294 (OMIM: 603346) PREDICTED: neuronal PAS do (410 aa)
initn: 291 init1: 151 opt: 317 Z-score: 221.8 bits: 50.8 E(85289): 1.3e-05
Smith-Waterman score: 317; 31.4% identity (58.4% similar) in 255 aa overlap (1-244:29-265)
10 20 30
pF1KSD MPRTMI--PPGECTYAGRKRRRPLQKQRPAVG
.: :. : : : : :: .:.:
XP_006 MAAPYPGSGGGSEVKCVGGRGASVPWDFLPGLMVKAPSGPCLQAQRK-----EKSR----
10 20 30 40 50
40 50 60 70 80 90
pF1KSD AEKSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQVVQEQ
: .. .: . : :. .::.:::.: : :.::: :..::::.:::.. : .
XP_006 ----NAARSRRGKENLEFFELAKLLPLPGAISSQLDKASIVRLSVTYLRLRRFAALGAPP
60 70 80 90 100
100 110 120 130 140
pF1KSD SSRQPAAGAPS---PGDSCPLAG-SAVLEGRL---LLESLNGFALVVSAEGTIFYASATI
. . ::: :. :: : : : :.: .: .:.::.::..... :: ..: : :.
XP_006 WGLR-AAGPPAGLAPGRRGPAALVSEVFEQHLGGHILQSLDGFVFALNQEGKFLYISETV
110 120 130 140 150 160
150 160 170 180 190 200
pF1KSD VDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQAPPLETGDDAILGRL
:::. :... ....:::: :... .:: : .:: ..... . :
XP_006 SIYLGLSQVEMTGSSVFDYIHPGDHSEVLEQLGLRTPTPG---PPTPPSVSSSSSSSSSL
170 180 190 200 210 220
210 220 230 240 250 260
pF1KSD LRAQEW-GTGTPTEYSAFLT-RCFICRVRCLLDSTSGFLARGSQAWQLRLCCPEPLMTMQ
. : .. : . :... : :. :.. : . :. ...:
XP_006 ADTPEIEASLTKVPPSSLVQERSFFVRMKSTL-TKRGLHVKASGYKVIHVTGRLRAHALG
230 240 250 260 270 280
270 280 290 300 310 320
pF1KSD FQGKLKFLFGQKKKAPSGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKPRADTAAT
XP_006 LVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRSCYQFV
290 300 310 320 330 340
>>XP_016882331 (OMIM: 603346) PREDICTED: neuronal PAS do (650 aa)
initn: 305 init1: 151 opt: 320 Z-score: 221.1 bits: 51.3 E(85289): 1.4e-05
Smith-Waterman score: 348; 25.9% identity (48.6% similar) in 599 aa overlap (1-550:29-584)
10 20 30
pF1KSD MPRTMI--PPGECTYAGRKRRRPLQKQRPAVG
.: :. : : : : :: .:.:
XP_016 MAAPYPGSGGGSEVKCVGGRGASVPWDFLPGLMVKAPSGPCLQAQRK-----EKSR----
10 20 30 40 50
40 50 60 70 80
pF1KSD AEKSNPSKRHRDRLNAELDHLASLLPFPPDIISKLDKLSVLRLSVSYLRVKSFFQV-VQE
: .. .: . : :. .::.:::.: : :.::: :..::::.:::.. : . .
XP_016 ----NAARSRRGKENLEFFELAKLLPLPGAISSQLDKASIVRLSVTYLRLRRFAALGAPP
60 70 80 90 100
90 100 110 120 130 140
pF1KSD QSSRQPAAGAPS---PGDSCPLAG-SAVLEGRL---LLESLNGFALVVSAEGTIFYASAT
. : ::: :. :: : : : :.: .: .:.::.::..... :: ..: : :
XP_016 WGLR--AAGPPAGLAPGRRGPAALVSEVFEQHLGGHILQSLDGFVFALNQEGKFLYISET
110 120 130 140 150 160
150 160 170 180 190 200
pF1KSD IVDYLGFHQTDVMHQNIYDYIHVDDRQDFCRQLHWAMDPPQVVFGQAPPLETGDDAILGR
. :::. :... ....:::: :... .:: : .:: ..... .
XP_016 VSIYLGLSQVEMTGSSVFDYIHPGDHSEVLEQLGLRTPTPG---PPTPPSVSSSSSSSSS
170 180 190 200 210 220
210 220 230 240 250 260
pF1KSD LLRAQEW-GTGTPTEYSAFLT-RCFICRVRCLLDSTSGFLARGSQAWQLRLCCPEPLMTM
: . : .. : . :... : :. :.. : . :. ...: .. .
XP_016 LADTPEIEASLTKVPPSSLVQERSFFVRMKSTL-TKRGLHVKASG---YKVIHVTGRLRA
230 240 250 260 270
270 280 290 300 310
pF1KSD QFQGKLKFLFGQKKKAP------SGAMLPPRLSLFCIAAPVLLPSAAEMKMRSALLRAKP
. : : : :: : :. :::: . .: . . : ..
XP_016 HALG-LVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELVGRS
280 290 300 310 320 330
320 330 340 350 360 370
pF1KSD RADTAATADA-KVKATTSLCESELHGKPNYSAGRSSRESGVLVLREQTDAGRWAQVPARA
. . :: ... . ::..:: :. . ..: : :: . .. :: :
XP_016 CYQFVHGQDATRIRQSHVDCETHLH-PPSLPTTPQTRASHSLV--PGSPSSGLPTVPPAA
340 350 360 370 380 390
380 390 400 410
pF1KSD PCLCLRGGPDLV------LDPKGGSGDREEEQ---HRMLSRASG---------VTGRRET
: : : . :. .: :. . . .: :.::.: :.: ..
XP_016 PT--APGTPFSIGRAARRLSDASGLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKS
400 410 420 430 440 450
420 430 440 450 460
pF1KSD PGPTKPLPWTAG--KHSEDGARP----RLQPSKNDPPSLRPMPRGSCLPCPCVQGTFRNS
:: . : :.. ...: : : .: : . : :. . : : ..: . .
XP_016 PGEHHVL-WVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTE-PEPPTEGK-QAA
460 470 480 490 500
470 480 490 500 510 520
pF1KSD PISHPPSPSPSAY-----SSRTSRPMRDVGEDQVHPPLCHFPQRSLQHQLPQPGAQRFAT
: . . . . : .. .: :... : : : :.:
XP_016 PAENEAPQTQGKRIKVEPGPRETKGSEDSGDED---PSSH-PAT------PRPEFTSVIR
510 520 530 540 550
530 540 550 560 570 580
pF1KSD RGYPMED-MKLQGVPMPPGDLCGPTLLLDVSIKMEKDSGCEGAADGCVPSQVWLGASDRS
: .: .. :. :::: ::::
XP_016 AGVLKQDPVRPWGLA-PPGDP-PPTLLHAGFLPPVVRGLCTPGTIRYGPAELGLVYPHLQ
560 570 580 590 600 610
719 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:30:00 2016 done: Thu Nov 3 05:30:02 2016
Total Scan time: 13.330 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]