FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1244, 1839 aa 1>>>pF1KSDA1244 1839 - 1839 aa - 1839 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1683+/- 0.001; mu= 20.3440+/- 0.060 mean_var=87.8621+/-17.284, 0's: 0 Z-trim(105.5): 18 B-trim: 0 in 0/52 Lambda= 0.136828 statistics sampled from 8449 (8453) to 8449 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.26), width: 16 Scan time: 7.010 The best scores are: opt bits E(32554) CCDS5189.2 ARFGEF3 gene_id:57221|Hs108|chr6 (2177) 12271 2433.6 0 >>CCDS5189.2 ARFGEF3 gene_id:57221|Hs108|chr6 (2177 aa) initn: 12271 init1: 12271 opt: 12271 Z-score: 13079.4 bits: 2433.6 E(32554): 0 Smith-Waterman score: 12271; 100.0% identity (100.0% similar) in 1839 aa overlap (1-1839:339-2177) 10 20 30 pF1KSD MKPVLQSLYHRVLLYPPPQHRVEAIKIMKE :::::::::::::::::::::::::::::: CCDS51 CTAPALSGPVARTIYYIAAELVRLVGSVDSMKPVLQSLYHRVLLYPPPQHRVEAIKIMKE 310 320 330 340 350 360 40 50 60 70 80 90 pF1KSD ILGSPQRLCDLAGPSSTESESRKRSISKRKSHLDLLKLIMDGMTEACIKGGIEACYAAVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 ILGSPQRLCDLAGPSSTESESRKRSISKRKSHLDLLKLIMDGMTEACIKGGIEACYAAVS 370 380 390 400 410 420 100 110 120 130 140 150 pF1KSD CVCTLLGALDELSQGKGLSEGQVQLLLLRLEELKDGAEWSRDSMEINEADFRWQRRVLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 CVCTLLGALDELSQGKGLSEGQVQLLLLRLEELKDGAEWSRDSMEINEADFRWQRRVLSS 430 440 450 460 470 480 160 170 180 190 200 210 pF1KSD EHTPWESGNERSLDISISVTTDTGQTTLEGELGQTTPEDHSGNHKNSLKSPAIPEGKETL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 EHTPWESGNERSLDISISVTTDTGQTTLEGELGQTTPEDHSGNHKNSLKSPAIPEGKETL 490 500 510 520 530 540 220 230 240 250 260 270 pF1KSD SKVLETEAVDQPDVVQRSHTVPYPDITNFLSVDCRTRSYGSRYSESNFSVDDQDLSRTEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 SKVLETEAVDQPDVVQRSHTVPYPDITNFLSVDCRTRSYGSRYSESNFSVDDQDLSRTEF 550 560 570 580 590 600 280 290 300 310 320 330 pF1KSD DSCDQYSMAAEKDSGRSDVSDIGSDNCSLADEEQTPRDCLGHRSLRTAALSLKLLKNQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 DSCDQYSMAAEKDSGRSDVSDIGSDNCSLADEEQTPRDCLGHRSLRTAALSLKLLKNQEA 610 620 630 640 650 660 340 350 360 370 380 390 pF1KSD DQHSARLFIQSLEGLLPRLLSLSNVEEVDTALQNFASTFCSGMMHSPGFDGNSSLSFQML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 DQHSARLFIQSLEGLLPRLLSLSNVEEVDTALQNFASTFCSGMMHSPGFDGNSSLSFQML 670 680 690 700 710 720 400 410 420 430 440 450 pF1KSD MNADSLYTAAHCALLLNLKLSHGDYYRKRPTLAPGVMKDFMKQVQTSGVLMVFSQAWIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 MNADSLYTAAHCALLLNLKLSHGDYYRKRPTLAPGVMKDFMKQVQTSGVLMVFSQAWIEE 730 740 750 760 770 780 460 470 480 490 500 510 pF1KSD LYHQVLDRNMLGEAGYWGSPEDNSLPLITMLTDIDGLESSAIGGQLMASAATESPFAQSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 LYHQVLDRNMLGEAGYWGSPEDNSLPLITMLTDIDGLESSAIGGQLMASAATESPFAQSR 790 800 810 820 830 840 520 530 540 550 560 570 pF1KSD RIDDSTVAGVAFARYILVGCWKNLIDTLSTPLTGRMAGSSKGLAFILGAEGIKEQNQKER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 RIDDSTVAGVAFARYILVGCWKNLIDTLSTPLTGRMAGSSKGLAFILGAEGIKEQNQKER 850 860 870 880 890 900 580 590 600 610 620 630 pF1KSD DAICMSLDGLRKAARLSCALGVAANCASALAQMAAASCVQEEKEEREAQEPSDAITQVKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 DAICMSLDGLRKAARLSCALGVAANCASALAQMAAASCVQEEKEEREAQEPSDAITQVKL 910 920 930 940 950 960 640 650 660 670 680 690 pF1KSD KVEQKLEQIGKVQGVWLHTAHVLCMEAILSVGLEMGSHNPDCWPHVFRVCEYVGTLEHNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 KVEQKLEQIGKVQGVWLHTAHVLCMEAILSVGLEMGSHNPDCWPHVFRVCEYVGTLEHNH 970 980 990 1000 1010 1020 700 710 720 730 740 750 pF1KSD FSDGASQPPLTISQPQKATGSAGLLGDPECEGSPPEHSPEQGRSLSTAPVVQPLSIQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 FSDGASQPPLTISQPQKATGSAGLLGDPECEGSPPEHSPEQGRSLSTAPVVQPLSIQDLV 1030 1040 1050 1060 1070 1080 760 770 780 790 800 810 pF1KSD REGSRGRASDFRGGSLMSGSSAAKVVLTLSTQADRLFEDATDKLNLMALGGFLYQLKKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 REGSRGRASDFRGGSLMSGSSAAKVVLTLSTQADRLFEDATDKLNLMALGGFLYQLKKAS 1090 1100 1110 1120 1130 1140 820 830 840 850 860 870 pF1KSD QSQLFHSVTDTVDYSLAMPGEVKSTQDRKSALHLFRLGNAMLRIVRSKARPLLHVMRCWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 QSQLFHSVTDTVDYSLAMPGEVKSTQDRKSALHLFRLGNAMLRIVRSKARPLLHVMRCWS 1150 1160 1170 1180 1190 1200 880 890 900 910 920 930 pF1KSD LVAPHLVEAACHKERHVSQKAVSFIHDILTEVLTDWNEPPHFHFNEALFRPFERIMQLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 LVAPHLVEAACHKERHVSQKAVSFIHDILTEVLTDWNEPPHFHFNEALFRPFERIMQLEL 1210 1220 1230 1240 1250 1260 940 950 960 970 980 990 pF1KSD CDEDVQDQVVTSIGELVEVCSTQIQSGWRPLFSALETVHGGNKSEMKEYLVGDYSMGKGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 CDEDVQDQVVTSIGELVEVCSTQIQSGWRPLFSALETVHGGNKSEMKEYLVGDYSMGKGQ 1270 1280 1290 1300 1310 1320 1000 1010 1020 1030 1040 1050 pF1KSD APVFDVFEAFLNTDNIQVFANAATSYIMCLMKFVKGLGEVDCKEIGDCAPAPGAPSTDLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 APVFDVFEAFLNTDNIQVFANAATSYIMCLMKFVKGLGEVDCKEIGDCAPAPGAPSTDLC 1330 1340 1350 1360 1370 1380 1060 1070 1080 1090 1100 1110 pF1KSD LPALDYLRRCSQLLAKIYKMPLKPIFLSGRLAGLPRRLQEQSASSEDGIESVLSDFDDDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 LPALDYLRRCSQLLAKIYKMPLKPIFLSGRLAGLPRRLQEQSASSEDGIESVLSDFDDDT 1390 1400 1410 1420 1430 1440 1120 1130 1140 1150 1160 1170 pF1KSD GLIEVWIILLEQLTAAVSNCPRQHQPPTLDLLFELLRDVTKTPGPGFGIYAVVHLLLPVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 GLIEVWIILLEQLTAAVSNCPRQHQPPTLDLLFELLRDVTKTPGPGFGIYAVVHLLLPVM 1450 1460 1470 1480 1490 1500 1180 1190 1200 1210 1220 1230 pF1KSD SVWLRRSHKDHSYWDMASANFKHAIGLSCELVVEHIQSFLHSDIRYESMINTMLKDLFEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 SVWLRRSHKDHSYWDMASANFKHAIGLSCELVVEHIQSFLHSDIRYESMINTMLKDLFEL 1510 1520 1530 1540 1550 1560 1240 1250 1260 1270 1280 1290 pF1KSD LVACVAKPTETISRVGCSCIRYVLVTAGPVFTEEMWRLACCALQDAFSATLKPVKDLLGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 LVACVAKPTETISRVGCSCIRYVLVTAGPVFTEEMWRLACCALQDAFSATLKPVKDLLGC 1570 1580 1590 1600 1610 1620 1300 1310 1320 1330 1340 1350 pF1KSD FHSGTESFSGEGCQVRVAAPSSSPSAEAEYWRIRAMAQQVFMLDTQCSPKTPNNFDHAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 FHSGTESFSGEGCQVRVAAPSSSPSAEAEYWRIRAMAQQVFMLDTQCSPKTPNNFDHAQS 1630 1640 1650 1660 1670 1680 1360 1370 1380 1390 1400 1410 pF1KSD CQLIIELPPDEKPNGHTKKSVSFREIVVSLLSHQVLLQNLYDILLEEFVKGPSPGEEKTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 CQLIIELPPDEKPNGHTKKSVSFREIVVSLLSHQVLLQNLYDILLEEFVKGPSPGEEKTI 1690 1700 1710 1720 1730 1740 1420 1430 1440 1450 1460 1470 pF1KSD QVPEAKLAGFLRYISMQNLAVIFDLLLDSYRTAREFDTSPGLKCLLKKVSGIGGAANLYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 QVPEAKLAGFLRYISMQNLAVIFDLLLDSYRTAREFDTSPGLKCLLKKVSGIGGAANLYR 1750 1760 1770 1780 1790 1800 1480 1490 1500 1510 1520 1530 pF1KSD QSAMSFNIYFHALVCAVLTNQETITAEQVKKVLFEDDERSTDSSQQCSSEDEDIFEETAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 QSAMSFNIYFHALVCAVLTNQETITAEQVKKVLFEDDERSTDSSQQCSSEDEDIFEETAQ 1810 1820 1830 1840 1850 1860 1540 1550 1560 1570 1580 1590 pF1KSD VSPPRGKEKRQWRARMPLLSVQPVSNADWVWLVKRLHKLCMELCNNYIQMHLDLENCMEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 VSPPRGKEKRQWRARMPLLSVQPVSNADWVWLVKRLHKLCMELCNNYIQMHLDLENCMEE 1870 1880 1890 1900 1910 1920 1600 1610 1620 1630 1640 1650 pF1KSD PPIFKGDPFFILPSFQSESSTPSTGGFSGKETPSEDDRSQSREHMGESLSLKAGGGDLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 PPIFKGDPFFILPSFQSESSTPSTGGFSGKETPSEDDRSQSREHMGESLSLKAGGGDLLL 1930 1940 1950 1960 1970 1980 1660 1670 1680 1690 1700 1710 pF1KSD PPSPKVEKKDPSRKKEWWENAGNKIYTMAADKTISKLMTEYKKRKQQHNLSAFPKEVKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 PPSPKVEKKDPSRKKEWWENAGNKIYTMAADKTISKLMTEYKKRKQQHNLSAFPKEVKVE 1990 2000 2010 2020 2030 2040 1720 1730 1740 1750 1760 1770 pF1KSD KKGEPLGPRGQDSPLLQRPQHLMDQGQMRHSFSAGPELLRQDKRPRSGSTGSSLSVSVRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 KKGEPLGPRGQDSPLLQRPQHLMDQGQMRHSFSAGPELLRQDKRPRSGSTGSSLSVSVRD 2050 2060 2070 2080 2090 2100 1780 1790 1800 1810 1820 1830 pF1KSD AEAQIQAWTNMVLTVLNQIQILPDQTFTALQPAVFPCISQLTCHVTDIRVRQAVREWLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 AEAQIQAWTNMVLTVLNQIQILPDQTFTALQPAVFPCISQLTCHVTDIRVRQAVREWLGR 2110 2120 2130 2140 2150 2160 pF1KSD VGRVYDIIV ::::::::: CCDS51 VGRVYDIIV 2170 1839 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:31:39 2016 done: Thu Nov 3 05:31:40 2016 Total Scan time: 7.010 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]