FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1247, 870 aa 1>>>pF1KSDA1247 870 - 870 aa - 870 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2471+/-0.0004; mu= 16.2905+/- 0.025 mean_var=86.6760+/-17.112, 0's: 0 Z-trim(113.0): 103 B-trim: 81 in 2/53 Lambda= 0.137760 statistics sampled from 21986 (22090) to 21986 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.259), width: 16 Scan time: 12.290 The best scores are: opt bits E(85289) XP_005260515 (OMIM: 610013) PREDICTED: extracellul ( 870) 6069 1216.9 0 XP_006723893 (OMIM: 610013) PREDICTED: extracellul ( 870) 6069 1216.9 0 NP_061325 (OMIM: 610013) extracellular sulfatase S ( 870) 6069 1216.9 0 NP_001155313 (OMIM: 610013) extracellular sulfatas ( 870) 6069 1216.9 0 XP_016883444 (OMIM: 610013) PREDICTED: extracellul ( 870) 6069 1216.9 0 XP_011527216 (OMIM: 610013) PREDICTED: extracellul ( 871) 6057 1214.5 0 XP_006723890 (OMIM: 610013) PREDICTED: extracellul ( 871) 6057 1214.5 0 XP_006723892 (OMIM: 610013) PREDICTED: extracellul ( 871) 6057 1214.5 0 XP_006723891 (OMIM: 610013) PREDICTED: extracellul ( 871) 6057 1214.5 0 XP_011527215 (OMIM: 610013) PREDICTED: extracellul ( 871) 6057 1214.5 0 NP_940998 (OMIM: 610013) extracellular sulfatase S ( 867) 6034 1209.9 0 XP_011527218 (OMIM: 610013) PREDICTED: extracellul ( 852) 5864 1176.1 0 XP_011527217 (OMIM: 610013) PREDICTED: extracellul ( 853) 5852 1173.7 0 XP_011515797 (OMIM: 610012) PREDICTED: extracellul ( 790) 2774 562.0 4e-159 XP_016868739 (OMIM: 610012) PREDICTED: extracellul ( 790) 2774 562.0 4e-159 NP_001121678 (OMIM: 610012) extracellular sulfatas ( 871) 2774 562.0 4.3e-159 NP_001121677 (OMIM: 610012) extracellular sulfatas ( 871) 2774 562.0 4.3e-159 NP_055985 (OMIM: 610012) extracellular sulfatase S ( 871) 2774 562.0 4.3e-159 NP_001121676 (OMIM: 610012) extracellular sulfatas ( 871) 2774 562.0 4.3e-159 XP_011515796 (OMIM: 610012) PREDICTED: extracellul (1122) 2774 562.0 5.4e-159 XP_006716503 (OMIM: 610012) PREDICTED: extracellul (1122) 2774 562.0 5.4e-159 XP_006716501 (OMIM: 610012) PREDICTED: extracellul (1122) 2774 562.0 5.4e-159 XP_006716502 (OMIM: 610012) PREDICTED: extracellul (1122) 2774 562.0 5.4e-159 XP_006716505 (OMIM: 610012) PREDICTED: extracellul ( 630) 1421 293.0 2.9e-78 XP_006716504 (OMIM: 610012) PREDICTED: extracellul ( 881) 1421 293.1 3.9e-78 NP_002067 (OMIM: 252940,607664) N-acetylglucosamin ( 552) 1044 218.1 9.3e-56 NP_937793 (OMIM: 610011) arylsulfatase K precursor ( 536) 329 76.0 5.4e-13 XP_005271961 (OMIM: 610011) PREDICTED: arylsulfata ( 377) 196 49.5 3.6e-05 NP_006114 (OMIM: 300823,309900) iduronate 2-sulfat ( 343) 171 44.5 0.001 XP_006721842 (OMIM: 610008) PREDICTED: arylsulfata ( 329) 168 43.9 0.0015 NP_000193 (OMIM: 300823,309900) iduronate 2-sulfat ( 550) 171 44.6 0.0016 XP_005257229 (OMIM: 610008) PREDICTED: arylsulfata ( 344) 168 43.9 0.0016 XP_016879857 (OMIM: 610008) PREDICTED: arylsulfata ( 413) 168 43.9 0.0019 XP_011522847 (OMIM: 610008) PREDICTED: arylsulfata ( 413) 168 43.9 0.0019 XP_011522845 (OMIM: 610008) PREDICTED: arylsulfata ( 427) 168 43.9 0.0019 XP_011522846 (OMIM: 610008) PREDICTED: arylsulfata ( 427) 168 43.9 0.0019 XP_016879855 (OMIM: 610008) PREDICTED: arylsulfata ( 461) 168 43.9 0.002 XP_016879856 (OMIM: 610008) PREDICTED: arylsulfata ( 461) 168 43.9 0.002 NP_001012301 (OMIM: 610009) arylsulfatase I precur ( 569) 169 44.2 0.0021 XP_011522844 (OMIM: 610008) PREDICTED: arylsulfata ( 488) 168 43.9 0.0021 XP_011522843 (OMIM: 610008) PREDICTED: arylsulfata ( 488) 168 43.9 0.0021 NP_055775 (OMIM: 610008) arylsulfatase G [Homo sap ( 525) 168 44.0 0.0023 XP_016879852 (OMIM: 610008) PREDICTED: arylsulfata ( 525) 168 44.0 0.0023 XP_005257227 (OMIM: 610008) PREDICTED: arylsulfata ( 525) 168 44.0 0.0023 XP_016879853 (OMIM: 610008) PREDICTED: arylsulfata ( 525) 168 44.0 0.0023 XP_016879851 (OMIM: 610008) PREDICTED: arylsulfata ( 525) 168 44.0 0.0023 NP_001254656 (OMIM: 610008) arylsulfatase G [Homo ( 525) 168 44.0 0.0023 XP_016879850 (OMIM: 610008) PREDICTED: arylsulfata ( 525) 168 44.0 0.0023 XP_016879854 (OMIM: 610008) PREDICTED: arylsulfata ( 525) 168 44.0 0.0023 XP_011522842 (OMIM: 610008) PREDICTED: arylsulfata ( 551) 168 44.0 0.0024 >>XP_005260515 (OMIM: 610013) PREDICTED: extracellular s (870 aa) initn: 6069 init1: 6069 opt: 6069 Z-score: 6516.4 bits: 1216.9 E(85289): 0 Smith-Waterman score: 6069; 99.9% identity (100.0% similar) in 870 aa overlap (1-870:1-870) 10 20 30 40 50 60 pF1KSD MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MQVMNKTRRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_005 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 790 800 810 820 830 840 850 860 870 pF1KSD QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG :::::::::::::::::::::::::::::: XP_005 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 850 860 870 >>XP_006723893 (OMIM: 610013) PREDICTED: extracellular s (870 aa) initn: 6069 init1: 6069 opt: 6069 Z-score: 6516.4 bits: 1216.9 E(85289): 0 Smith-Waterman score: 6069; 99.9% identity (100.0% similar) in 870 aa overlap (1-870:1-870) 10 20 30 40 50 60 pF1KSD MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MQVMNKTRRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_006 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 790 800 810 820 830 840 850 860 870 pF1KSD QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG :::::::::::::::::::::::::::::: XP_006 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 850 860 870 >>NP_061325 (OMIM: 610013) extracellular sulfatase Sulf- (870 aa) initn: 6069 init1: 6069 opt: 6069 Z-score: 6516.4 bits: 1216.9 E(85289): 0 Smith-Waterman score: 6069; 99.9% identity (100.0% similar) in 870 aa overlap (1-870:1-870) 10 20 30 40 50 60 pF1KSD MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MQVMNKTRRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_061 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 790 800 810 820 830 840 850 860 870 pF1KSD QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG :::::::::::::::::::::::::::::: NP_061 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 850 860 870 >>NP_001155313 (OMIM: 610013) extracellular sulfatase Su (870 aa) initn: 6069 init1: 6069 opt: 6069 Z-score: 6516.4 bits: 1216.9 E(85289): 0 Smith-Waterman score: 6069; 99.9% identity (100.0% similar) in 870 aa overlap (1-870:1-870) 10 20 30 40 50 60 pF1KSD MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MQVMNKTRRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_001 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 790 800 810 820 830 840 850 860 870 pF1KSD QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG :::::::::::::::::::::::::::::: NP_001 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 850 860 870 >>XP_016883444 (OMIM: 610013) PREDICTED: extracellular s (870 aa) initn: 6069 init1: 6069 opt: 6069 Z-score: 6516.4 bits: 1216.9 E(85289): 0 Smith-Waterman score: 6069; 99.9% identity (100.0% similar) in 870 aa overlap (1-870:1-870) 10 20 30 40 50 60 pF1KSD MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MQVMNKTRRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_016 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEEC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTC 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYE 790 800 810 820 830 840 850 860 870 pF1KSD QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG :::::::::::::::::::::::::::::: XP_016 QYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 850 860 870 >>XP_011527216 (OMIM: 610013) PREDICTED: extracellular s (871 aa) initn: 4139 init1: 4139 opt: 6057 Z-score: 6503.5 bits: 1214.5 E(85289): 0 Smith-Waterman score: 6057; 99.8% identity (99.9% similar) in 871 aa overlap (1-870:1-871) 10 20 30 40 50 60 pF1KSD MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MQVMNKTRRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_011 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 550 560 570 580 590 600 610 620 630 640 650 pF1KSD HR-CYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEE :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD CDCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CDCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDT 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD CSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFL 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD EYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSY 790 800 810 820 830 840 840 850 860 870 pF1KSD EQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG ::::::::::::::::::::::::::::::: XP_011 EQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 850 860 870 >>XP_006723890 (OMIM: 610013) PREDICTED: extracellular s (871 aa) initn: 4139 init1: 4139 opt: 6057 Z-score: 6503.5 bits: 1214.5 E(85289): 0 Smith-Waterman score: 6057; 99.8% identity (99.9% similar) in 871 aa overlap (1-870:1-871) 10 20 30 40 50 60 pF1KSD MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MQVMNKTRRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_006 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 550 560 570 580 590 600 610 620 630 640 650 pF1KSD HR-CYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEE :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HRRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD CDCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CDCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDT 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD CSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFL 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD EYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSY 790 800 810 820 830 840 840 850 860 870 pF1KSD EQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG ::::::::::::::::::::::::::::::: XP_006 EQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 850 860 870 >>XP_006723892 (OMIM: 610013) PREDICTED: extracellular s (871 aa) initn: 4139 init1: 4139 opt: 6057 Z-score: 6503.5 bits: 1214.5 E(85289): 0 Smith-Waterman score: 6057; 99.8% identity (99.9% similar) in 871 aa overlap (1-870:1-871) 10 20 30 40 50 60 pF1KSD MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MQVMNKTRRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_006 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 550 560 570 580 590 600 610 620 630 640 650 pF1KSD HR-CYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEE :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HRRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD CDCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CDCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDT 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD CSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFL 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD EYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSY 790 800 810 820 830 840 840 850 860 870 pF1KSD EQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG ::::::::::::::::::::::::::::::: XP_006 EQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 850 860 870 >>XP_006723891 (OMIM: 610013) PREDICTED: extracellular s (871 aa) initn: 4139 init1: 4139 opt: 6057 Z-score: 6503.5 bits: 1214.5 E(85289): 0 Smith-Waterman score: 6057; 99.8% identity (99.9% similar) in 871 aa overlap (1-870:1-871) 10 20 30 40 50 60 pF1KSD MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MQVMNKTRRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_006 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 550 560 570 580 590 600 610 620 630 640 650 pF1KSD HR-CYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEE :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HRRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD CDCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CDCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDT 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD CSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFL 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD EYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSY 790 800 810 820 830 840 840 850 860 870 pF1KSD EQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG ::::::::::::::::::::::::::::::: XP_006 EQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 850 860 870 >>XP_011527215 (OMIM: 610013) PREDICTED: extracellular s (871 aa) initn: 4139 init1: 4139 opt: 6057 Z-score: 6503.5 bits: 1214.5 E(85289): 0 Smith-Waterman score: 6057; 99.8% identity (99.9% similar) in 871 aa overlap (1-870:1-871) 10 20 30 40 50 60 pF1KSD MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGPPSLVLCLLSATVFSLLGGSSAFLSHHRLKGRFQRDRRNIRPNIILVLTDDQDVELGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD MQVMNKTRRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_011 MQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKHGSDYSKDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYNM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGCLNPHIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNIDLAPTILDIAGLDIPADMDGKSILKLLDTERPVNRFHLKKKMRVWRDSFLVERGKLL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKRDNDKVDAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDATGKLKLHKCKGP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRLGGSRALSNLVPKYYGQGSEACTCDSGDYKLSLAGRRKKLFKKKYKASYVRSRSIRSV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIEVDGRVYHVGLGDAAQPRNLTKRHWPGAPEDQDDKDGGDFSGTGGLPDYSAANPIKVT 550 560 570 580 590 600 610 620 630 640 650 pF1KSD HR-CYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEE :: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD CDCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CDCHKISYHTQHKGRLKHRGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDT 670 680 690 700 710 720 720 730 740 750 760 770 pF1KSD CSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSMPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFL 730 740 750 760 770 780 780 790 800 810 820 830 pF1KSD EYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSY 790 800 810 820 830 840 840 850 860 870 pF1KSD EQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG ::::::::::::::::::::::::::::::: XP_011 EQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG 850 860 870 870 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:33:06 2016 done: Thu Nov 3 05:33:08 2016 Total Scan time: 12.290 Total Display time: 0.380 Function used was FASTA [36.3.4 Apr, 2011]