FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1258, 454 aa 1>>>pF1KSDA1258 454 - 454 aa - 454 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3367+/-0.000492; mu= 16.9581+/- 0.030 mean_var=62.2263+/-12.630, 0's: 0 Z-trim(108.0): 42 B-trim: 506 in 2/46 Lambda= 0.162588 statistics sampled from 16038 (16075) to 16038 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.542), E-opt: 0.2 (0.188), width: 16 Scan time: 7.380 The best scores are: opt bits E(85289) NP_004284 (OMIM: 139260) guanine deaminase isoform ( 454) 2984 709.2 5.7e-204 XP_005252374 (OMIM: 139260) PREDICTED: guanine dea ( 471) 2984 709.2 5.9e-204 XP_016870825 (OMIM: 139260) PREDICTED: guanine dea ( 471) 2984 709.2 5.9e-204 NP_001229434 (OMIM: 139260) guanine deaminase isof ( 471) 2984 709.2 5.9e-204 XP_016870826 (OMIM: 139260) PREDICTED: guanine dea ( 460) 2842 675.9 6.1e-194 XP_016870828 (OMIM: 139260) PREDICTED: guanine dea ( 412) 2679 637.6 1.8e-182 XP_011517522 (OMIM: 139260) PREDICTED: guanine dea ( 429) 2679 637.6 1.9e-182 NP_001229436 (OMIM: 139260) guanine deaminase isof ( 380) 2454 584.8 1.3e-166 NP_001229435 (OMIM: 139260) guanine deaminase isof ( 380) 2454 584.8 1.3e-166 XP_011517523 (OMIM: 139260) PREDICTED: guanine dea ( 397) 2454 584.9 1.3e-166 XP_016870827 (OMIM: 139260) PREDICTED: guanine dea ( 449) 2092 500.0 5.4e-141 XP_011517521 (OMIM: 139260) PREDICTED: guanine dea ( 467) 2092 500.0 5.6e-141 XP_011517520 (OMIM: 139260) PREDICTED: guanine dea ( 469) 2092 500.0 5.7e-141 XP_011517519 (OMIM: 139260) PREDICTED: guanine dea ( 492) 2092 500.0 5.9e-141 XP_011517516 (OMIM: 139260) PREDICTED: guanine dea ( 509) 2092 500.0 6.1e-141 XP_011517524 (OMIM: 139260) PREDICTED: guanine dea ( 509) 2092 500.0 6.1e-141 XP_016870822 (OMIM: 139260) PREDICTED: guanine dea ( 509) 2092 500.0 6.1e-141 XP_011517515 (OMIM: 139260) PREDICTED: guanine dea ( 509) 2092 500.0 6.1e-141 XP_016870823 (OMIM: 139260) PREDICTED: guanine dea ( 498) 1950 466.7 6.3e-131 XP_016870824 (OMIM: 139260) PREDICTED: guanine dea ( 498) 1950 466.7 6.3e-131 XP_011517518 (OMIM: 139260) PREDICTED: guanine dea ( 498) 1950 466.7 6.3e-131 XP_011517517 (OMIM: 139260) PREDICTED: guanine dea ( 498) 1950 466.7 6.3e-131 XP_016870829 (OMIM: 139260) PREDICTED: guanine dea ( 301) 1817 435.4 1e-121 XP_011517525 (OMIM: 139260) PREDICTED: guanine dea ( 301) 1817 435.4 1e-121 >>NP_004284 (OMIM: 139260) guanine deaminase isoform b [ (454 aa) initn: 2984 init1: 2984 opt: 2984 Z-score: 3782.9 bits: 709.2 E(85289): 5.7e-204 Smith-Waterman score: 2984; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KSD MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI 370 380 390 400 410 420 430 440 450 pF1KSD SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV :::::::::::::::::::::::::::::::::: NP_004 SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV 430 440 450 >>XP_005252374 (OMIM: 139260) PREDICTED: guanine deamina (471 aa) initn: 2984 init1: 2984 opt: 2984 Z-score: 3782.7 bits: 709.2 E(85289): 5.9e-204 Smith-Waterman score: 2984; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KSD MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI 370 380 390 400 410 420 430 440 450 pF1KSD SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV :::::::::::::::::::::::::::::::::: XP_005 SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSVKETIHLPASSPHPPPFP 430 440 450 460 470 >>XP_016870825 (OMIM: 139260) PREDICTED: guanine deamina (471 aa) initn: 2984 init1: 2984 opt: 2984 Z-score: 3782.7 bits: 709.2 E(85289): 5.9e-204 Smith-Waterman score: 2984; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KSD MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI 370 380 390 400 410 420 430 440 450 pF1KSD SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV :::::::::::::::::::::::::::::::::: XP_016 SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSVKETIHLPASSPHPPPFP 430 440 450 460 470 >>NP_001229434 (OMIM: 139260) guanine deaminase isoform (471 aa) initn: 2984 init1: 2984 opt: 2984 Z-score: 3782.7 bits: 709.2 E(85289): 5.9e-204 Smith-Waterman score: 2984; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KSD MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI 370 380 390 400 410 420 430 440 450 pF1KSD SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV :::::::::::::::::::::::::::::::::: NP_001 SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSVKETIHLPASSPHPPPFP 430 440 450 460 470 >>XP_016870826 (OMIM: 139260) PREDICTED: guanine deamina (460 aa) initn: 2842 init1: 2842 opt: 2842 Z-score: 3602.8 bits: 675.9 E(85289): 6.1e-194 Smith-Waterman score: 2842; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KSD MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI 370 380 390 400 410 420 430 440 450 pF1KSD SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV :::::::::::: XP_016 SEAVIQKFLYLGKKQFTYQPPHPILHHFLNVPWYFQRNTL 430 440 450 460 >>XP_016870828 (OMIM: 139260) PREDICTED: guanine deamina (412 aa) initn: 2679 init1: 2679 opt: 2679 Z-score: 3396.9 bits: 637.6 E(85289): 1.8e-182 Smith-Waterman score: 2679; 99.8% identity (100.0% similar) in 412 aa overlap (43-454:1-412) 20 30 40 50 60 70 pF1KSD FRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCFKPCEIRELSHHE .::::::::::::::::::::::::::::: XP_016 MFLEEASQQEKLAKEWCFKPCEIRELSHHE 10 20 30 80 90 100 110 120 130 pF1KSD FFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFAEEVYTRVVRRTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFAEEVYTRVVRRTL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KSD KNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYKETTEESIKETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYKETTEESIKETE 100 110 120 130 140 150 200 210 220 230 240 250 pF1KSD RFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVK 160 170 180 190 200 210 260 270 280 290 300 310 pF1KSD NLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGF 220 230 240 250 260 270 320 330 340 350 360 370 pF1KSD LNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLA 280 290 300 310 320 330 380 390 400 410 420 430 pF1KSD TLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQKFLYLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQKFLYLG 340 350 360 370 380 390 440 450 pF1KSD DDRNIEEVYVGGKQVVPFSSSV :::::::::::::::::::::: XP_016 DDRNIEEVYVGGKQVVPFSSSV 400 410 >>XP_011517522 (OMIM: 139260) PREDICTED: guanine deamina (429 aa) initn: 2679 init1: 2679 opt: 2679 Z-score: 3396.6 bits: 637.6 E(85289): 1.9e-182 Smith-Waterman score: 2679; 99.8% identity (100.0% similar) in 412 aa overlap (43-454:1-412) 20 30 40 50 60 70 pF1KSD FRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCFKPCEIRELSHHE .::::::::::::::::::::::::::::: XP_011 MFLEEASQQEKLAKEWCFKPCEIRELSHHE 10 20 30 80 90 100 110 120 130 pF1KSD FFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFAEEVYTRVVRRTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFAEEVYTRVVRRTL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KSD KNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYKETTEESIKETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYKETTEESIKETE 100 110 120 130 140 150 200 210 220 230 240 250 pF1KSD RFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSHISENRDEVEAVK 160 170 180 190 200 210 260 270 280 290 300 310 pF1KSD NLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGF 220 230 240 250 260 270 320 330 340 350 360 370 pF1KSD LNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLA 280 290 300 310 320 330 380 390 400 410 420 430 pF1KSD TLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQKFLYLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQKFLYLG 340 350 360 370 380 390 440 450 pF1KSD DDRNIEEVYVGGKQVVPFSSSV :::::::::::::::::::::: XP_011 DDRNIEEVYVGGKQVVPFSSSVKETIHLPASSPHPPPFP 400 410 420 >>NP_001229436 (OMIM: 139260) guanine deaminase isoform (380 aa) initn: 2454 init1: 2454 opt: 2454 Z-score: 3112.2 bits: 584.8 E(85289): 1.3e-166 Smith-Waterman score: 2454; 100.0% identity (100.0% similar) in 380 aa overlap (75-454:1-380) 50 60 70 80 90 100 pF1KSD LEEASQQEKLAKEWCFKPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLT :::::::::::::::::::::::::::::: NP_001 MPGLVDTHIHASQYSFAGSSIDLPLLEWLT 10 20 30 110 120 130 140 150 160 pF1KSD KYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRA 40 50 60 70 80 90 170 180 190 200 210 220 pF1KSD FVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KSD ELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLS 160 170 180 190 200 210 290 300 310 320 330 340 pF1KSD AEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIR 220 230 240 250 260 270 350 360 370 380 390 400 pF1KSD RAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKA 280 290 300 310 320 330 410 420 430 440 450 pF1KSD SDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV 340 350 360 370 380 >>NP_001229435 (OMIM: 139260) guanine deaminase isoform (380 aa) initn: 2454 init1: 2454 opt: 2454 Z-score: 3112.2 bits: 584.8 E(85289): 1.3e-166 Smith-Waterman score: 2454; 100.0% identity (100.0% similar) in 380 aa overlap (75-454:1-380) 50 60 70 80 90 100 pF1KSD LEEASQQEKLAKEWCFKPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLT :::::::::::::::::::::::::::::: NP_001 MPGLVDTHIHASQYSFAGSSIDLPLLEWLT 10 20 30 110 120 130 140 150 160 pF1KSD KYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRA 40 50 60 70 80 90 170 180 190 200 210 220 pF1KSD FVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KSD ELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLS 160 170 180 190 200 210 290 300 310 320 330 340 pF1KSD AEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIR 220 230 240 250 260 270 350 360 370 380 390 400 pF1KSD RAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKA 280 290 300 310 320 330 410 420 430 440 450 pF1KSD SDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV 340 350 360 370 380 >>XP_011517523 (OMIM: 139260) PREDICTED: guanine deamina (397 aa) initn: 2454 init1: 2454 opt: 2454 Z-score: 3111.9 bits: 584.9 E(85289): 1.3e-166 Smith-Waterman score: 2454; 100.0% identity (100.0% similar) in 380 aa overlap (75-454:1-380) 50 60 70 80 90 100 pF1KSD LEEASQQEKLAKEWCFKPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLT :::::::::::::::::::::::::::::: XP_011 MPGLVDTHIHASQYSFAGSSIDLPLLEWLT 10 20 30 110 120 130 140 150 160 pF1KSD KYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRA 40 50 60 70 80 90 170 180 190 200 210 220 pF1KSD FVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVGKVCMDLNDTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMG 100 110 120 130 140 150 230 240 250 260 270 280 pF1KSD ELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELGNIAKTRDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLS 160 170 180 190 200 210 290 300 310 320 330 340 pF1KSD AEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIR 220 230 240 250 260 270 350 360 370 380 390 400 pF1KSD RAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKA 280 290 300 310 320 330 410 420 430 440 450 pF1KSD SDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSVKETIHLPASS 340 350 360 370 380 390 XP_011 PHPPPFP 454 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:36:13 2016 done: Thu Nov 3 05:36:14 2016 Total Scan time: 7.380 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]