FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1264, 719 aa 1>>>pF1KSDA1264 719 - 719 aa - 719 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.2424+/-0.000547; mu= -14.3445+/- 0.033 mean_var=550.6603+/-121.780, 0's: 0 Z-trim(118.4): 1904 B-trim: 33 in 1/55 Lambda= 0.054655 statistics sampled from 28877 (31412) to 28877 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.368), width: 16 Scan time: 13.390 The best scores are: opt bits E(85289) XP_016883451 (OMIM: 608038) PREDICTED: serine/thre ( 719) 4871 400.1 1.6e-110 NP_817127 (OMIM: 608038) serine/threonine-protein ( 719) 4871 400.1 1.6e-110 XP_016883453 (OMIM: 608038) PREDICTED: serine/thre ( 719) 4871 400.1 1.6e-110 XP_016883452 (OMIM: 608038) PREDICTED: serine/thre ( 719) 4871 400.1 1.6e-110 XP_016883454 (OMIM: 608038) PREDICTED: serine/thre ( 719) 4871 400.1 1.6e-110 NP_065074 (OMIM: 608038) serine/threonine-protein ( 719) 4871 400.1 1.6e-110 XP_016883450 (OMIM: 608038) PREDICTED: serine/thre ( 719) 4871 400.1 1.6e-110 XP_016883449 (OMIM: 608038) PREDICTED: serine/thre ( 719) 4871 400.1 1.6e-110 XP_011524622 (OMIM: 605451) PREDICTED: serine/thre ( 438) 1730 152.2 4.1e-36 NP_001014834 (OMIM: 605451) serine/threonine-prote ( 438) 1730 152.2 4.1e-36 NP_001014835 (OMIM: 605451) serine/threonine-prote ( 438) 1730 152.2 4.1e-36 NP_001014832 (OMIM: 605451) serine/threonine-prote ( 591) 1726 152.0 6.2e-36 NP_001014831 (OMIM: 605451) serine/threonine-prote ( 591) 1726 152.0 6.2e-36 XP_011524618 (OMIM: 605451) PREDICTED: serine/thre ( 591) 1726 152.0 6.2e-36 XP_011524621 (OMIM: 605451) PREDICTED: serine/thre ( 591) 1726 152.0 6.2e-36 XP_011524619 (OMIM: 605451) PREDICTED: serine/thre ( 591) 1726 152.0 6.2e-36 NP_005875 (OMIM: 605451) serine/threonine-protein ( 591) 1726 152.0 6.2e-36 XP_011524620 (OMIM: 605451) PREDICTED: serine/thre ( 591) 1726 152.0 6.2e-36 NP_064553 (OMIM: 608110) serine/threonine-protein ( 681) 1542 137.6 1.6e-31 NP_001263646 (OMIM: 608110) serine/threonine-prote ( 681) 1542 137.6 1.6e-31 NP_001263647 (OMIM: 608110) serine/threonine-prote ( 636) 1082 101.3 1.3e-20 XP_016873338 (OMIM: 602590) PREDICTED: serine/thre ( 545) 1065 99.9 2.9e-20 XP_016873335 (OMIM: 602590) PREDICTED: serine/thre ( 545) 1065 99.9 2.9e-20 XP_016873339 (OMIM: 602590) PREDICTED: serine/thre ( 545) 1065 99.9 2.9e-20 NP_002567 (OMIM: 602590) serine/threonine-protein ( 545) 1065 99.9 2.9e-20 XP_016873337 (OMIM: 602590) PREDICTED: serine/thre ( 545) 1065 99.9 2.9e-20 XP_016873336 (OMIM: 602590) PREDICTED: serine/thre ( 545) 1065 99.9 2.9e-20 NP_001121638 (OMIM: 300142,300558) serine/threonin ( 544) 1064 99.8 3e-20 NP_001311260 (OMIM: 300142,300558) serine/threonin ( 544) 1064 99.8 3e-20 NP_001311259 (OMIM: 300142,300558) serine/threonin ( 544) 1064 99.8 3e-20 NP_001311254 (OMIM: 300142,300558) serine/threonin ( 544) 1064 99.8 3e-20 XP_016885050 (OMIM: 300142,300558) PREDICTED: seri ( 544) 1064 99.8 3e-20 NP_001311263 (OMIM: 300142,300558) serine/threonin ( 544) 1064 99.8 3e-20 NP_001311261 (OMIM: 300142,300558) serine/threonin ( 544) 1064 99.8 3e-20 NP_001121639 (OMIM: 300142,300558) serine/threonin ( 544) 1064 99.8 3e-20 NP_001311255 (OMIM: 300142,300558) serine/threonin ( 544) 1064 99.8 3e-20 NP_002569 (OMIM: 300142,300558) serine/threonine-p ( 544) 1064 99.8 3e-20 NP_001121645 (OMIM: 300142,300558) serine/threonin ( 559) 1064 99.8 3.1e-20 NP_001311257 (OMIM: 300142,300558) serine/threonin ( 559) 1064 99.8 3.1e-20 NP_001311256 (OMIM: 300142,300558) serine/threonin ( 559) 1064 99.8 3.1e-20 XP_016885046 (OMIM: 300142,300558) PREDICTED: seri ( 559) 1064 99.8 3.1e-20 NP_001311258 (OMIM: 300142,300558) serine/threonin ( 559) 1064 99.8 3.1e-20 NP_001311262 (OMIM: 300142,300558) serine/threonin ( 559) 1064 99.8 3.1e-20 NP_001121644 (OMIM: 300142,300558) serine/threonin ( 565) 1064 99.8 3.1e-20 XP_016885052 (OMIM: 300142,300558) PREDICTED: seri ( 580) 1064 99.8 3.2e-20 NP_001121640 (OMIM: 300142,300558) serine/threonin ( 580) 1064 99.8 3.2e-20 NP_002568 (OMIM: 605022) serine/threonine-protein ( 524) 1031 97.2 1.8e-19 XP_016861990 (OMIM: 605022) PREDICTED: serine/thre ( 524) 1031 97.2 1.8e-19 XP_011511172 (OMIM: 605022) PREDICTED: serine/thre ( 524) 1031 97.2 1.8e-19 XP_011543385 (OMIM: 602590) PREDICTED: serine/thre ( 553) 1005 95.2 7.7e-19 >>XP_016883451 (OMIM: 608038) PREDICTED: serine/threonin (719 aa) initn: 4871 init1: 4871 opt: 4871 Z-score: 2105.3 bits: 400.1 E(85289): 1.6e-110 Smith-Waterman score: 4871; 100.0% identity (100.0% similar) in 719 aa overlap (1-719:1-719) 10 20 30 40 50 60 pF1KSD MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP 610 620 630 640 650 660 670 680 690 700 710 pF1KSD PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH 670 680 690 700 710 >>NP_817127 (OMIM: 608038) serine/threonine-protein kina (719 aa) initn: 4871 init1: 4871 opt: 4871 Z-score: 2105.3 bits: 400.1 E(85289): 1.6e-110 Smith-Waterman score: 4871; 100.0% identity (100.0% similar) in 719 aa overlap (1-719:1-719) 10 20 30 40 50 60 pF1KSD MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP 610 620 630 640 650 660 670 680 690 700 710 pF1KSD PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_817 PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH 670 680 690 700 710 >>XP_016883453 (OMIM: 608038) PREDICTED: serine/threonin (719 aa) initn: 4871 init1: 4871 opt: 4871 Z-score: 2105.3 bits: 400.1 E(85289): 1.6e-110 Smith-Waterman score: 4871; 100.0% identity (100.0% similar) in 719 aa overlap (1-719:1-719) 10 20 30 40 50 60 pF1KSD MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP 610 620 630 640 650 660 670 680 690 700 710 pF1KSD PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH 670 680 690 700 710 >>XP_016883452 (OMIM: 608038) PREDICTED: serine/threonin (719 aa) initn: 4871 init1: 4871 opt: 4871 Z-score: 2105.3 bits: 400.1 E(85289): 1.6e-110 Smith-Waterman score: 4871; 100.0% identity (100.0% similar) in 719 aa overlap (1-719:1-719) 10 20 30 40 50 60 pF1KSD MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP 610 620 630 640 650 660 670 680 690 700 710 pF1KSD PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH 670 680 690 700 710 >>XP_016883454 (OMIM: 608038) PREDICTED: serine/threonin (719 aa) initn: 4871 init1: 4871 opt: 4871 Z-score: 2105.3 bits: 400.1 E(85289): 1.6e-110 Smith-Waterman score: 4871; 100.0% identity (100.0% similar) in 719 aa overlap (1-719:1-719) 10 20 30 40 50 60 pF1KSD MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP 610 620 630 640 650 660 670 680 690 700 710 pF1KSD PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH 670 680 690 700 710 >>NP_065074 (OMIM: 608038) serine/threonine-protein kina (719 aa) initn: 4871 init1: 4871 opt: 4871 Z-score: 2105.3 bits: 400.1 E(85289): 1.6e-110 Smith-Waterman score: 4871; 100.0% identity (100.0% similar) in 719 aa overlap (1-719:1-719) 10 20 30 40 50 60 pF1KSD MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP 610 620 630 640 650 660 670 680 690 700 710 pF1KSD PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH 670 680 690 700 710 >>XP_016883450 (OMIM: 608038) PREDICTED: serine/threonin (719 aa) initn: 4871 init1: 4871 opt: 4871 Z-score: 2105.3 bits: 400.1 E(85289): 1.6e-110 Smith-Waterman score: 4871; 100.0% identity (100.0% similar) in 719 aa overlap (1-719:1-719) 10 20 30 40 50 60 pF1KSD MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP 610 620 630 640 650 660 670 680 690 700 710 pF1KSD PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH 670 680 690 700 710 >>XP_016883449 (OMIM: 608038) PREDICTED: serine/threonin (719 aa) initn: 4871 init1: 4871 opt: 4871 Z-score: 2105.3 bits: 400.1 E(85289): 1.6e-110 Smith-Waterman score: 4871; 100.0% identity (100.0% similar) in 719 aa overlap (1-719:1-719) 10 20 30 40 50 60 pF1KSD MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSHGPGHA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EENGFITFSQYSSESDTTADYTTEKYREKSLYGDDLDPYYRGSHAAKQNGHVMKMKHGEA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYSEVKPLKSDFARFSADYHSHLDSLSKPSEYSDLKWEYQRASSSSPLDYSFQFTPSRTA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTSGCSKESLAYSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSKSGYSSSSHQYPSGYHKATLYHHPSLQSSSQYISTASYLSSLSLSSSTYPPPSWGSSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRM 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP 610 620 630 640 650 660 670 680 690 700 710 pF1KSD PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH 670 680 690 700 710 >>XP_011524622 (OMIM: 605451) PREDICTED: serine/threonin (438 aa) initn: 2085 init1: 1681 opt: 1730 Z-score: 769.4 bits: 152.2 E(85289): 4.1e-36 Smith-Waterman score: 1732; 65.6% identity (77.4% similar) in 425 aa overlap (302-717:23-436) 280 290 300 310 320 330 pF1KSD YLNQTSPQPTMRQRSRSGSGLQEPMMPFGASAFKTHPQGHSYNSYTYPRLSEPTMCIPKV ..: : : . . : : . :: XP_011 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKP 10 20 30 40 50 340 350 360 370 380 pF1KSD DYDRAQMVL----SPPLSGSDTYPRGPAK----LPQSQSKSGYSSSSHQYPSGYHKATLY : : .. .: :. : ::. .::: :::: . :. . : XP_011 LVDPACITSIQPGAPKGEPHDVAPNGPSAGGLAIPQS------SSSSSRPPTRARGA--- 60 70 80 90 100 390 400 410 420 430 440 pF1KSD HHPSLQSSSQYISTASYLS-SLSLSSSTYPPPSWGSSSDQQPSRVSHEQFRAALQLVVSP :: . . : . . . .. . : : : ...:.:::::::::::::::.: XP_011 --PSPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDP 110 120 130 140 150 160 450 460 470 480 490 500 pF1KSD GDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYH :::: :: ::::::::::::::::: . .:: :::::::::::::::::::::::::::. XP_011 GDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQ 170 180 190 200 210 220 510 520 530 540 550 560 pF1KSD HDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIATVCLSVLRALSYLHNQ :.:::.::.:::::::::::::::::::::::::::::::::::.:::.::.::: :: : XP_011 HENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQ 230 240 250 260 270 280 570 580 590 600 610 620 pF1KSD GVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGT ::::::::::::::: :::.::::::::::::::::.::::::::::::::.::::::: XP_011 GVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGP 290 300 310 320 330 340 630 640 650 660 670 680 pF1KSD EVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPPRVKDLHKVSSVLRGFLDLMLV ::::::::::::::.::::::::::::.::. :::.::::.:.::::: :.:::: .:: XP_011 EVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLV 350 360 370 380 390 400 690 700 710 pF1KSD REPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH :.:.::::: ::: :::: ::::. ::::::: : XP_011 RDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 410 420 430 >>NP_001014834 (OMIM: 605451) serine/threonine-protein k (438 aa) initn: 2085 init1: 1681 opt: 1730 Z-score: 769.4 bits: 152.2 E(85289): 4.1e-36 Smith-Waterman score: 1732; 65.6% identity (77.4% similar) in 425 aa overlap (302-717:23-436) 280 290 300 310 320 330 pF1KSD YLNQTSPQPTMRQRSRSGSGLQEPMMPFGASAFKTHPQGHSYNSYTYPRLSEPTMCIPKV ..: : : . . : : . :: NP_001 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKP 10 20 30 40 50 340 350 360 370 380 pF1KSD DYDRAQMVL----SPPLSGSDTYPRGPAK----LPQSQSKSGYSSSSHQYPSGYHKATLY : : .. .: :. : ::. .::: :::: . :. . : NP_001 LVDPACITSIQPGAPKGEPHDVAPNGPSAGGLAIPQS------SSSSSRPPTRARGA--- 60 70 80 90 100 390 400 410 420 430 440 pF1KSD HHPSLQSSSQYISTASYLS-SLSLSSSTYPPPSWGSSSDQQPSRVSHEQFRAALQLVVSP :: . . : . . . .. . : : : ...:.:::::::::::::::.: NP_001 --PSPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVSHEQFRAALQLVVDP 110 120 130 140 150 160 450 460 470 480 490 500 pF1KSD GDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYH :::: :: ::::::::::::::::: . .:: :::::::::::::::::::::::::::. NP_001 GDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQ 170 180 190 200 210 220 510 520 530 540 550 560 pF1KSD HDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIATVCLSVLRALSYLHNQ :.:::.::.:::::::::::::::::::::::::::::::::::.:::.::.::: :: : NP_001 HENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQ 230 240 250 260 270 280 570 580 590 600 610 620 pF1KSD GVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVISRLPYGT ::::::::::::::: :::.::::::::::::::::.::::::::::::::.::::::: NP_001 GVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGP 290 300 310 320 330 340 630 640 650 660 670 680 pF1KSD EVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPPRVKDLHKVSSVLRGFLDLMLV ::::::::::::::.::::::::::::.::. :::.::::.:.::::: :.:::: .:: NP_001 EVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLV 350 360 370 380 390 400 690 700 710 pF1KSD REPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH :.:.::::: ::: :::: ::::. ::::::: : NP_001 RDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR 410 420 430 719 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:39:24 2016 done: Thu Nov 3 05:39:26 2016 Total Scan time: 13.390 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]