FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1267, 1105 aa 1>>>pF1KSDA1267 1105 - 1105 aa - 1105 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.9755+/-0.000386; mu= 4.6224+/- 0.024 mean_var=184.2587+/-36.914, 0's: 0 Z-trim(119.1): 47 B-trim: 77 in 1/54 Lambda= 0.094484 statistics sampled from 32657 (32708) to 32657 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.383), width: 16 Scan time: 12.230 The best scores are: opt bits E(85289) NP_056258 (OMIM: 610443,612452) KAT8 regulatory NS (1105) 7251 1001.6 0 XP_006721886 (OMIM: 610443,612452) PREDICTED: KAT8 (1105) 7251 1001.6 0 XP_006721887 (OMIM: 610443,612452) PREDICTED: KAT8 (1105) 7251 1001.6 0 NP_001180395 (OMIM: 610443,612452) KAT8 regulatory (1105) 7251 1001.6 0 XP_011522930 (OMIM: 610443,612452) PREDICTED: KAT8 (1104) 7232 999.0 0 NP_001180394 (OMIM: 610443,612452) KAT8 regulatory (1104) 7232 999.0 0 XP_011522933 (OMIM: 610443,612452) PREDICTED: KAT8 (1041) 4793 666.6 2.2e-190 XP_016879977 (OMIM: 610443,612452) PREDICTED: KAT8 (1041) 4793 666.6 2.2e-190 XP_011522932 (OMIM: 610443,612452) PREDICTED: KAT8 (1042) 4793 666.6 2.2e-190 XP_011522934 (OMIM: 610443,612452) PREDICTED: KAT8 ( 695) 4546 632.8 2.1e-180 XP_011522931 (OMIM: 610443,612452) PREDICTED: KAT8 (1071) 3992 557.4 1.6e-157 XP_016879978 (OMIM: 610443,612452) PREDICTED: KAT8 ( 878) 3033 426.6 3.1e-118 XP_005246391 (OMIM: 613833) PREDICTED: KAT8 regula ( 550) 389 66.1 6.5e-10 XP_006712383 (OMIM: 613833) PREDICTED: KAT8 regula ( 572) 389 66.1 6.8e-10 XP_011509011 (OMIM: 613833) PREDICTED: KAT8 regula ( 614) 389 66.1 7.2e-10 NP_001294905 (OMIM: 613833) KAT8 regulatory NSL co ( 945) 389 66.2 1e-09 XP_005246389 (OMIM: 613833) PREDICTED: KAT8 regula ( 978) 389 66.2 1.1e-09 NP_689732 (OMIM: 613833) KAT8 regulatory NSL compl ( 987) 389 66.2 1.1e-09 XP_005246386 (OMIM: 613833) PREDICTED: KAT8 regula ( 987) 389 66.2 1.1e-09 XP_011509009 (OMIM: 613833) PREDICTED: KAT8 regula ( 987) 389 66.2 1.1e-09 XP_011509008 (OMIM: 613833) PREDICTED: KAT8 regula ( 987) 389 66.2 1.1e-09 XP_005246387 (OMIM: 613833) PREDICTED: KAT8 regula ( 987) 389 66.2 1.1e-09 XP_016858919 (OMIM: 613833) PREDICTED: KAT8 regula ( 987) 389 66.2 1.1e-09 XP_005246385 (OMIM: 613833) PREDICTED: KAT8 regula (1020) 389 66.2 1.1e-09 XP_016858920 (OMIM: 613833) PREDICTED: KAT8 regula ( 514) 350 60.8 2.5e-08 XP_011509012 (OMIM: 613833) PREDICTED: KAT8 regula ( 559) 350 60.8 2.6e-08 >>NP_056258 (OMIM: 610443,612452) KAT8 regulatory NSL co (1105 aa) initn: 7251 init1: 7251 opt: 7251 Z-score: 5349.5 bits: 1001.6 E(85289): 0 Smith-Waterman score: 7251; 99.9% identity (99.9% similar) in 1105 aa overlap (1-1105:1-1105) 10 20 30 40 50 60 pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_056 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP 1030 1040 1050 1060 1070 1080 1090 1100 pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR ::::::::::::::::::::::::: NP_056 TSPPIVPLKSRHLVAAATAQRPTHR 1090 1100 >>XP_006721886 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1105 aa) initn: 7251 init1: 7251 opt: 7251 Z-score: 5349.5 bits: 1001.6 E(85289): 0 Smith-Waterman score: 7251; 99.9% identity (99.9% similar) in 1105 aa overlap (1-1105:1-1105) 10 20 30 40 50 60 pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_006 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP 1030 1040 1050 1060 1070 1080 1090 1100 pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR ::::::::::::::::::::::::: XP_006 TSPPIVPLKSRHLVAAATAQRPTHR 1090 1100 >>XP_006721887 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1105 aa) initn: 7251 init1: 7251 opt: 7251 Z-score: 5349.5 bits: 1001.6 E(85289): 0 Smith-Waterman score: 7251; 99.9% identity (99.9% similar) in 1105 aa overlap (1-1105:1-1105) 10 20 30 40 50 60 pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_006 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP 1030 1040 1050 1060 1070 1080 1090 1100 pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR ::::::::::::::::::::::::: XP_006 TSPPIVPLKSRHLVAAATAQRPTHR 1090 1100 >>NP_001180395 (OMIM: 610443,612452) KAT8 regulatory NSL (1105 aa) initn: 7251 init1: 7251 opt: 7251 Z-score: 5349.5 bits: 1001.6 E(85289): 0 Smith-Waterman score: 7251; 99.9% identity (99.9% similar) in 1105 aa overlap (1-1105:1-1105) 10 20 30 40 50 60 pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_001 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP 1030 1040 1050 1060 1070 1080 1090 1100 pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR ::::::::::::::::::::::::: NP_001 TSPPIVPLKSRHLVAAATAQRPTHR 1090 1100 >>XP_011522930 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1104 aa) initn: 5550 init1: 5550 opt: 7232 Z-score: 5335.5 bits: 999.0 E(85289): 0 Smith-Waterman score: 7232; 99.8% identity (99.8% similar) in 1105 aa overlap (1-1105:1-1104) 10 20 30 40 50 60 pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVTASTSQ-PVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG 850 860 870 880 890 910 920 930 940 950 960 pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_011 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP 1020 1030 1040 1050 1060 1070 1090 1100 pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR ::::::::::::::::::::::::: XP_011 TSPPIVPLKSRHLVAAATAQRPTHR 1080 1090 1100 >>NP_001180394 (OMIM: 610443,612452) KAT8 regulatory NSL (1104 aa) initn: 5550 init1: 5550 opt: 7232 Z-score: 5335.5 bits: 999.0 E(85289): 0 Smith-Waterman score: 7232; 99.8% identity (99.8% similar) in 1105 aa overlap (1-1105:1-1104) 10 20 30 40 50 60 pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVTASTSQ-PVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG 850 860 870 880 890 910 920 930 940 950 960 pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_001 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP 1020 1030 1040 1050 1060 1070 1090 1100 pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR ::::::::::::::::::::::::: NP_001 TSPPIVPLKSRHLVAAATAQRPTHR 1080 1090 1100 >>XP_011522933 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1041 aa) initn: 4793 init1: 4793 opt: 4793 Z-score: 3539.1 bits: 666.6 E(85289): 2.2e-190 Smith-Waterman score: 6649; 94.0% identity (94.1% similar) in 1105 aa overlap (1-1105:1-1041) 10 20 30 40 50 60 pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD :::::::::::::: XP_011 KDRHKLVSSFLTTA---------------------------------------------- 730 790 800 810 820 830 840 pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS .:::::::::::::::::::::::::::::::::::::::::: XP_011 -----------------MLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS 740 750 760 770 850 860 870 880 890 900 pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVTASTSQ-PVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG 780 790 800 810 820 830 910 920 930 940 950 960 pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG 840 850 860 870 880 890 970 980 990 1000 1010 1020 pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_011 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC 900 910 920 930 940 950 1030 1040 1050 1060 1070 1080 pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP 960 970 980 990 1000 1010 1090 1100 pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR ::::::::::::::::::::::::: XP_011 TSPPIVPLKSRHLVAAATAQRPTHR 1020 1030 1040 >>XP_016879977 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1041 aa) initn: 4793 init1: 4793 opt: 4793 Z-score: 3539.1 bits: 666.6 E(85289): 2.2e-190 Smith-Waterman score: 6649; 94.0% identity (94.1% similar) in 1105 aa overlap (1-1105:1-1041) 10 20 30 40 50 60 pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD :::::::::::::: XP_016 KDRHKLVSSFLTTA---------------------------------------------- 730 790 800 810 820 830 840 pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS .:::::::::::::::::::::::::::::::::::::::::: XP_016 -----------------MLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS 740 750 760 770 850 860 870 880 890 900 pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG :::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVTASTSQ-PVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG 780 790 800 810 820 830 910 920 930 940 950 960 pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG 840 850 860 870 880 890 970 980 990 1000 1010 1020 pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_016 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC 900 910 920 930 940 950 1030 1040 1050 1060 1070 1080 pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP 960 970 980 990 1000 1010 1090 1100 pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR ::::::::::::::::::::::::: XP_016 TSPPIVPLKSRHLVAAATAQRPTHR 1020 1030 1040 >>XP_011522932 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1042 aa) initn: 4791 init1: 4791 opt: 4793 Z-score: 3539.1 bits: 666.6 E(85289): 2.2e-190 Smith-Waterman score: 6668; 94.1% identity (94.2% similar) in 1105 aa overlap (1-1105:1-1042) 10 20 30 40 50 60 pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD :::::::::::::: XP_011 KDRHKLVSSFLTTA---------------------------------------------- 730 790 800 810 820 830 840 pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS .:::::::::::::::::::::::::::::::::::::::::: XP_011 -----------------MLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS 740 750 760 770 850 860 870 880 890 900 pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG 780 790 800 810 820 830 910 920 930 940 950 960 pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG 840 850 860 870 880 890 970 980 990 1000 1010 1020 pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: XP_011 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC 900 910 920 930 940 950 1030 1040 1050 1060 1070 1080 pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP 960 970 980 990 1000 1010 1090 1100 pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR ::::::::::::::::::::::::: XP_011 TSPPIVPLKSRHLVAAATAQRPTHR 1020 1030 1040 >>XP_011522934 (OMIM: 610443,612452) PREDICTED: KAT8 reg (695 aa) initn: 4546 init1: 4546 opt: 4546 Z-score: 3359.8 bits: 632.8 E(85289): 2.1e-180 Smith-Waterman score: 4546; 99.9% identity (99.9% similar) in 675 aa overlap (431-1105:21-695) 410 420 430 440 450 460 pF1KSD DVTDSSSGGESDIEEEELTRADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLE :::::::::::::::::::::::::::::: XP_011 MYPWVTTLDGYVKMEKEQMRRRRSEWKWAADRAAIVSRWNWLQAHVSDLE 10 20 30 40 50 470 480 490 500 510 520 pF1KSD YRIRQQTDIYKQIRANKGLIVLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRIRQQTDIYKQIRANKGLIVLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLE 60 70 80 90 100 110 530 540 550 560 570 580 pF1KSD NHGAPIIGHISESLSTKSCGALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NHGAPIIGHISESLSTKSCGALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLV 120 130 140 150 160 170 590 600 610 620 630 640 pF1KSD SSSSDGTCVAARTRPVLSCKKRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSSSDGTCVAARTRPVLSCKKRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGS 180 190 200 210 220 230 650 660 670 680 690 700 pF1KSD INTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 INTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPP 240 250 260 270 280 290 710 720 730 740 750 760 pF1KSD KKLSLKHRAPMPGSLPDSARKDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKLSLKHRAPMPGSLPDSARKDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMV 300 310 320 330 340 350 770 780 790 800 810 820 pF1KSD ERVTAPKAERLLNPPPPVHDPNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERVTAPKAERLLNPPPPVHDPNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHS 360 370 380 390 400 410 830 840 850 860 870 880 pF1KSD PLVRQLSTSSDSPAPASSSSQVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLVRQLSTSSDSPAPASSSSQVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKL 420 430 440 450 460 470 890 900 910 920 930 940 pF1KSD QYKEILTPSWREVDLQSLKGSPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QYKEILTPSWREVDLQSLKGSPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPP 480 490 500 510 520 530 950 960 970 980 990 1000 pF1KSD QRRGSRSYRSSDGRTTPQLGSANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRRGSRSYRSSDGRTTPQLGSANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSA 540 550 560 570 580 590 1010 1020 1030 1040 1050 1060 pF1KSD PLTPVARDTLRHLASEDTRCSTPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERA ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLTPVARDTPRHLASEDTRCSTPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERA 600 610 620 630 640 650 1070 1080 1090 1100 pF1KSD ARCTRRTSGSKTGRETEAAPTSPPIVPLKSRHLVAAATAQRPTHR ::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARCTRRTSGSKTGRETEAAPTSPPIVPLKSRHLVAAATAQRPTHR 660 670 680 690 1105 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:40:49 2016 done: Thu Nov 3 05:40:50 2016 Total Scan time: 12.230 Total Display time: 0.450 Function used was FASTA [36.3.4 Apr, 2011]