FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1267, 1105 aa
1>>>pF1KSDA1267 1105 - 1105 aa - 1105 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9755+/-0.000386; mu= 4.6224+/- 0.024
mean_var=184.2587+/-36.914, 0's: 0 Z-trim(119.1): 47 B-trim: 77 in 1/54
Lambda= 0.094484
statistics sampled from 32657 (32708) to 32657 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.383), width: 16
Scan time: 12.230
The best scores are: opt bits E(85289)
NP_056258 (OMIM: 610443,612452) KAT8 regulatory NS (1105) 7251 1001.6 0
XP_006721886 (OMIM: 610443,612452) PREDICTED: KAT8 (1105) 7251 1001.6 0
XP_006721887 (OMIM: 610443,612452) PREDICTED: KAT8 (1105) 7251 1001.6 0
NP_001180395 (OMIM: 610443,612452) KAT8 regulatory (1105) 7251 1001.6 0
XP_011522930 (OMIM: 610443,612452) PREDICTED: KAT8 (1104) 7232 999.0 0
NP_001180394 (OMIM: 610443,612452) KAT8 regulatory (1104) 7232 999.0 0
XP_011522933 (OMIM: 610443,612452) PREDICTED: KAT8 (1041) 4793 666.6 2.2e-190
XP_016879977 (OMIM: 610443,612452) PREDICTED: KAT8 (1041) 4793 666.6 2.2e-190
XP_011522932 (OMIM: 610443,612452) PREDICTED: KAT8 (1042) 4793 666.6 2.2e-190
XP_011522934 (OMIM: 610443,612452) PREDICTED: KAT8 ( 695) 4546 632.8 2.1e-180
XP_011522931 (OMIM: 610443,612452) PREDICTED: KAT8 (1071) 3992 557.4 1.6e-157
XP_016879978 (OMIM: 610443,612452) PREDICTED: KAT8 ( 878) 3033 426.6 3.1e-118
XP_005246391 (OMIM: 613833) PREDICTED: KAT8 regula ( 550) 389 66.1 6.5e-10
XP_006712383 (OMIM: 613833) PREDICTED: KAT8 regula ( 572) 389 66.1 6.8e-10
XP_011509011 (OMIM: 613833) PREDICTED: KAT8 regula ( 614) 389 66.1 7.2e-10
NP_001294905 (OMIM: 613833) KAT8 regulatory NSL co ( 945) 389 66.2 1e-09
XP_005246389 (OMIM: 613833) PREDICTED: KAT8 regula ( 978) 389 66.2 1.1e-09
NP_689732 (OMIM: 613833) KAT8 regulatory NSL compl ( 987) 389 66.2 1.1e-09
XP_005246386 (OMIM: 613833) PREDICTED: KAT8 regula ( 987) 389 66.2 1.1e-09
XP_011509009 (OMIM: 613833) PREDICTED: KAT8 regula ( 987) 389 66.2 1.1e-09
XP_011509008 (OMIM: 613833) PREDICTED: KAT8 regula ( 987) 389 66.2 1.1e-09
XP_005246387 (OMIM: 613833) PREDICTED: KAT8 regula ( 987) 389 66.2 1.1e-09
XP_016858919 (OMIM: 613833) PREDICTED: KAT8 regula ( 987) 389 66.2 1.1e-09
XP_005246385 (OMIM: 613833) PREDICTED: KAT8 regula (1020) 389 66.2 1.1e-09
XP_016858920 (OMIM: 613833) PREDICTED: KAT8 regula ( 514) 350 60.8 2.5e-08
XP_011509012 (OMIM: 613833) PREDICTED: KAT8 regula ( 559) 350 60.8 2.6e-08
>>NP_056258 (OMIM: 610443,612452) KAT8 regulatory NSL co (1105 aa)
initn: 7251 init1: 7251 opt: 7251 Z-score: 5349.5 bits: 1001.6 E(85289): 0
Smith-Waterman score: 7251; 99.9% identity (99.9% similar) in 1105 aa overlap (1-1105:1-1105)
10 20 30 40 50 60
pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_056 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
1030 1040 1050 1060 1070 1080
1090 1100
pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR
:::::::::::::::::::::::::
NP_056 TSPPIVPLKSRHLVAAATAQRPTHR
1090 1100
>>XP_006721886 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1105 aa)
initn: 7251 init1: 7251 opt: 7251 Z-score: 5349.5 bits: 1001.6 E(85289): 0
Smith-Waterman score: 7251; 99.9% identity (99.9% similar) in 1105 aa overlap (1-1105:1-1105)
10 20 30 40 50 60
pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_006 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
1030 1040 1050 1060 1070 1080
1090 1100
pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR
:::::::::::::::::::::::::
XP_006 TSPPIVPLKSRHLVAAATAQRPTHR
1090 1100
>>XP_006721887 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1105 aa)
initn: 7251 init1: 7251 opt: 7251 Z-score: 5349.5 bits: 1001.6 E(85289): 0
Smith-Waterman score: 7251; 99.9% identity (99.9% similar) in 1105 aa overlap (1-1105:1-1105)
10 20 30 40 50 60
pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_006 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
1030 1040 1050 1060 1070 1080
1090 1100
pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR
:::::::::::::::::::::::::
XP_006 TSPPIVPLKSRHLVAAATAQRPTHR
1090 1100
>>NP_001180395 (OMIM: 610443,612452) KAT8 regulatory NSL (1105 aa)
initn: 7251 init1: 7251 opt: 7251 Z-score: 5349.5 bits: 1001.6 E(85289): 0
Smith-Waterman score: 7251; 99.9% identity (99.9% similar) in 1105 aa overlap (1-1105:1-1105)
10 20 30 40 50 60
pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
1030 1040 1050 1060 1070 1080
1090 1100
pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR
:::::::::::::::::::::::::
NP_001 TSPPIVPLKSRHLVAAATAQRPTHR
1090 1100
>>XP_011522930 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1104 aa)
initn: 5550 init1: 5550 opt: 7232 Z-score: 5335.5 bits: 999.0 E(85289): 0
Smith-Waterman score: 7232; 99.8% identity (99.8% similar) in 1105 aa overlap (1-1105:1-1104)
10 20 30 40 50 60
pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVTASTSQ-PVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
850 860 870 880 890
910 920 930 940 950 960
pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
1020 1030 1040 1050 1060 1070
1090 1100
pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR
:::::::::::::::::::::::::
XP_011 TSPPIVPLKSRHLVAAATAQRPTHR
1080 1090 1100
>>NP_001180394 (OMIM: 610443,612452) KAT8 regulatory NSL (1104 aa)
initn: 5550 init1: 5550 opt: 7232 Z-score: 5335.5 bits: 999.0 E(85289): 0
Smith-Waterman score: 7232; 99.8% identity (99.8% similar) in 1105 aa overlap (1-1105:1-1104)
10 20 30 40 50 60
pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVTASTSQ-PVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
850 860 870 880 890
910 920 930 940 950 960
pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
1020 1030 1040 1050 1060 1070
1090 1100
pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR
:::::::::::::::::::::::::
NP_001 TSPPIVPLKSRHLVAAATAQRPTHR
1080 1090 1100
>>XP_011522933 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1041 aa)
initn: 4793 init1: 4793 opt: 4793 Z-score: 3539.1 bits: 666.6 E(85289): 2.2e-190
Smith-Waterman score: 6649; 94.0% identity (94.1% similar) in 1105 aa overlap (1-1105:1-1041)
10 20 30 40 50 60
pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
::::::::::::::
XP_011 KDRHKLVSSFLTTA----------------------------------------------
730
790 800 810 820 830 840
pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
.::::::::::::::::::::::::::::::::::::::::::
XP_011 -----------------MLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
740 750 760 770
850 860 870 880 890 900
pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVTASTSQ-PVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
780 790 800 810 820 830
910 920 930 940 950 960
pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
840 850 860 870 880 890
970 980 990 1000 1010 1020
pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC
900 910 920 930 940 950
1030 1040 1050 1060 1070 1080
pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
960 970 980 990 1000 1010
1090 1100
pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR
:::::::::::::::::::::::::
XP_011 TSPPIVPLKSRHLVAAATAQRPTHR
1020 1030 1040
>>XP_016879977 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1041 aa)
initn: 4793 init1: 4793 opt: 4793 Z-score: 3539.1 bits: 666.6 E(85289): 2.2e-190
Smith-Waterman score: 6649; 94.0% identity (94.1% similar) in 1105 aa overlap (1-1105:1-1041)
10 20 30 40 50 60
pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
::::::::::::::
XP_016 KDRHKLVSSFLTTA----------------------------------------------
730
790 800 810 820 830 840
pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
.::::::::::::::::::::::::::::::::::::::::::
XP_016 -----------------MLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
740 750 760 770
850 860 870 880 890 900
pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVTASTSQ-PVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
780 790 800 810 820 830
910 920 930 940 950 960
pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
840 850 860 870 880 890
970 980 990 1000 1010 1020
pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC
900 910 920 930 940 950
1030 1040 1050 1060 1070 1080
pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
960 970 980 990 1000 1010
1090 1100
pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR
:::::::::::::::::::::::::
XP_016 TSPPIVPLKSRHLVAAATAQRPTHR
1020 1030 1040
>>XP_011522932 (OMIM: 610443,612452) PREDICTED: KAT8 reg (1042 aa)
initn: 4791 init1: 4791 opt: 4793 Z-score: 3539.1 bits: 666.6 E(85289): 2.2e-190
Smith-Waterman score: 6668; 94.1% identity (94.2% similar) in 1105 aa overlap (1-1105:1-1042)
10 20 30 40 50 60
pF1KSD MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAMAPALTDAAAEAHHIRFKLAPPSSTLSPGSAENNGNANILIAANGTKRKAIAAEDPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAELLGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALTSSALHGGEMGGSESGDLKGGMTNCTLPHRSLDVEHTTLYSNNSTANKSSVNSMEQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALDSDTRITALLRRQADIESRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTSEGLSNFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLSTKSCG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGSINTMPPEIHYEAPLLERLSQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSAR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD KDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHD
::::::::::::::
XP_011 KDRHKLVSSFLTTA----------------------------------------------
730
790 800 810 820 830 840
pF1KSD PNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
.::::::::::::::::::::::::::::::::::::::::::
XP_011 -----------------MLKHHTDMSSSSYLAATHHPPHSPLVRQLSTSSDSPAPASSSS
740 750 760 770
850 860 870 880 890 900
pF1KSD QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG
780 790 800 810 820 830
910 920 930 940 950 960
pF1KSD SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLG
840 850 860 870 880 890
970 980 990 1000 1010 1020
pF1KSD SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTLRHLASEDTRC
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 SANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDTPRHLASEDTRC
900 910 920 930 940 950
1030 1040 1050 1060 1070 1080
pF1KSD STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERAARCTRRTSGSKTGRETEAAP
960 970 980 990 1000 1010
1090 1100
pF1KSD TSPPIVPLKSRHLVAAATAQRPTHR
:::::::::::::::::::::::::
XP_011 TSPPIVPLKSRHLVAAATAQRPTHR
1020 1030 1040
>>XP_011522934 (OMIM: 610443,612452) PREDICTED: KAT8 reg (695 aa)
initn: 4546 init1: 4546 opt: 4546 Z-score: 3359.8 bits: 632.8 E(85289): 2.1e-180
Smith-Waterman score: 4546; 99.9% identity (99.9% similar) in 675 aa overlap (431-1105:21-695)
410 420 430 440 450 460
pF1KSD DVTDSSSGGESDIEEEELTRADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLE
::::::::::::::::::::::::::::::
XP_011 MYPWVTTLDGYVKMEKEQMRRRRSEWKWAADRAAIVSRWNWLQAHVSDLE
10 20 30 40 50
470 480 490 500 510 520
pF1KSD YRIRQQTDIYKQIRANKGLIVLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRIRQQTDIYKQIRANKGLIVLGEVPPPEHTTDLFLPLSSEVKTDHGTDKLIESVSQPLE
60 70 80 90 100 110
530 540 550 560 570 580
pF1KSD NHGAPIIGHISESLSTKSCGALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHGAPIIGHISESLSTKSCGALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLV
120 130 140 150 160 170
590 600 610 620 630 640
pF1KSD SSSSDGTCVAARTRPVLSCKKRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSSDGTCVAARTRPVLSCKKRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPSCALCGSGS
180 190 200 210 220 230
650 660 670 680 690 700
pF1KSD INTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPP
240 250 260 270 280 290
710 720 730 740 750 760
pF1KSD KKLSLKHRAPMPGSLPDSARKDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLSLKHRAPMPGSLPDSARKDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMV
300 310 320 330 340 350
770 780 790 800 810 820
pF1KSD ERVTAPKAERLLNPPPPVHDPNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERVTAPKAERLLNPPPPVHDPNHSKMRLRDHSSERSEVLKHHTDMSSSSYLAATHHPPHS
360 370 380 390 400 410
830 840 850 860 870 880
pF1KSD PLVRQLSTSSDSPAPASSSSQVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLVRQLSTSSDSPAPASSSSQVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKL
420 430 440 450 460 470
890 900 910 920 930 940
pF1KSD QYKEILTPSWREVDLQSLKGSPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYKEILTPSWREVDLQSLKGSPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPP
480 490 500 510 520 530
950 960 970 980 990 1000
pF1KSD QRRGSRSYRSSDGRTTPQLGSANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRRGSRSYRSSDGRTTPQLGSANPSTPQPASPDVSSSHSLSEYSHGQSPRSPISPELHSA
540 550 560 570 580 590
1010 1020 1030 1040 1050 1060
pF1KSD PLTPVARDTLRHLASEDTRCSTPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERA
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLTPVARDTPRHLASEDTRCSTPELGLDEQSVQPWERRTFPLAHSPQAECEDQLDAQERA
600 610 620 630 640 650
1070 1080 1090 1100
pF1KSD ARCTRRTSGSKTGRETEAAPTSPPIVPLKSRHLVAAATAQRPTHR
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARCTRRTSGSKTGRETEAAPTSPPIVPLKSRHLVAAATAQRPTHR
660 670 680 690
1105 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:40:49 2016 done: Thu Nov 3 05:40:50 2016
Total Scan time: 12.230 Total Display time: 0.450
Function used was FASTA [36.3.4 Apr, 2011]