FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1317, 428 aa 1>>>pF1KSDA1317 428 - 428 aa - 428 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0300+/-0.000826; mu= 14.4780+/- 0.050 mean_var=88.8813+/-17.543, 0's: 0 Z-trim(109.3): 36 B-trim: 28 in 1/51 Lambda= 0.136041 statistics sampled from 10782 (10817) to 10782 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.332), width: 16 Scan time: 3.080 The best scores are: opt bits E(32554) CCDS34260.1 KCTD16 gene_id:57528|Hs108|chr5 ( 428) 2943 587.5 8.3e-168 CCDS3467.1 KCTD8 gene_id:386617|Hs108|chr4 ( 473) 1144 234.4 1.8e-61 CCDS9455.1 KCTD12 gene_id:115207|Hs108|chr13 ( 325) 599 127.4 2e-29 CCDS31645.1 KCTD21 gene_id:283219|Hs108|chr11 ( 260) 298 68.3 1e-11 >>CCDS34260.1 KCTD16 gene_id:57528|Hs108|chr5 (428 aa) initn: 2943 init1: 2943 opt: 2943 Z-score: 3126.1 bits: 587.5 E(32554): 8.3e-168 Smith-Waterman score: 2943; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS 370 380 390 400 410 420 pF1KSD ELLRKYHL :::::::: CCDS34 ELLRKYHL >>CCDS3467.1 KCTD8 gene_id:386617|Hs108|chr4 (473 aa) initn: 1681 init1: 652 opt: 1144 Z-score: 1217.3 bits: 234.4 E(32554): 1.8e-61 Smith-Waterman score: 1669; 61.7% identity (78.2% similar) in 441 aa overlap (16-428:35-473) 10 20 30 40 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLIS : .:. :::::::::::::: :.::::.: CCDS34 DTGSGGSTILPISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KSD IPHSLLWKMFSPK--RDTA---NDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHF .: : : .::::. : : ..: .::..:::::::::::::.::::::.:..::.:: CCDS34 VPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHF 70 80 90 100 110 120 110 120 130 140 150 pF1KSD PEKGRLKREAEYFQLPDLVKLLTPDEIKQSP--DEFCHSDFED-ASQGSDTRIC--PPSS ::: :: :::::::: ::::::.: ::. :: :.::.:: .::::. . .. CCDS34 PEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAA 130 140 150 160 170 180 160 170 180 190 200 pF1KSD LLPA--------------DRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLA .:. :.. ::.:.::::: : :..::::::::: ::.:::::.:: CCDS34 AVPSGPGAHGGGGGGGAQDKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALA 190 200 210 220 230 240 210 220 230 240 250 260 pF1KSD KEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSVTASFINQ :::::.:::::::::: ::.::::::::: .::.::: ::: :::::::::: ::.:.:: CCDS34 KEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGTAAFVNQ 250 260 270 280 290 300 270 280 290 300 310 pF1KSD YTDDKIWSSYTEYVFYREPSRW-SPSHCDCCCKNGK-GDKEGESGTSCNDLSTSSCDSQS : :::::::::::.:.: :.. ::.. :. : :: .:::::::.::::::::.: CCDS34 YRDDKIWSSYTEYIFFRPPQKIVSPKQEHEDRKHDKVTDKGSESGTSCNELSTSSCDSHS 310 320 330 340 350 360 320 330 340 350 360 370 pF1KSD EASSPQE--TVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMRRKSDLLRTLTSGSRESN :::.::. . ...: : ::::: ::.::: : . ::.:.:..:: : :::.: CCDS34 EASTPQDNPSSAQQATAHQPNTLTLDRPSKKAPVQWIPPPDKRRNSELFQTLISKSRETN 370 380 390 400 410 420 380 390 400 410 420 pF1KSD MSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQSELLRKYHL .:.:: : ::::.:::..:::::: ::.::: :::::. ::::::.:: : CCDS34 LSKKK--VCEKLSVEEEMKKCIQDFKKIHIPDYFPERKRQWQSELLQKYGL 430 440 450 460 470 >>CCDS9455.1 KCTD12 gene_id:115207|Hs108|chr13 (325 aa) initn: 1086 init1: 515 opt: 599 Z-score: 641.6 bits: 127.4 E(32554): 2e-29 Smith-Waterman score: 1033; 56.0% identity (73.5% similar) in 302 aa overlap (17-279:26-325) 10 20 30 40 50 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLL :: : ::..:::::::::: ::. :..:.: ::: CCDS94 MALADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD WKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAE :.::. .. ..::.:::::::.:::::::::::::::: :.::::.:::..::.:::: CCDS94 WRMFTQQQP--QELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAE 70 80 90 100 110 120 130 140 pF1KSD YFQLPDLVKLL-TPDEIKQSP--------------DEFCHSDF------EDASQGSDTR- ::.::.::. : .:.. .: ::. . : :: :. . CCDS94 YFELPELVRRLGAPQQPGPGPPPSRRGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPT 120 130 140 150 160 170 150 160 170 180 190 pF1KSD ---------------ICPPSSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILV . ::. : ..:. :.::.::::: :.::..::::::::: :: : CCDS94 LELASRSPSGGAAGPLLTPSQSLDGSRRSGYITIGYRGSYTIGRDAQADAKFRRVARITV 180 190 200 210 220 230 200 210 220 230 240 250 pF1KSD CGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSV ::. ::::::::.:::::::::: :::::::.::::. ::.::: ::: :::::::.:. CCDS94 CGKTSLAKEVFGDTLNESRDPDRPPERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTG 240 250 260 270 280 290 260 270 280 290 300 310 pF1KSD TASFINQ--YTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKEGESGTSCNDLST : .: .. ..::::.::::::: :: CCDS94 TCAFASSTDQSEDKIWTSYTEYVFCRE 300 310 320 >>CCDS31645.1 KCTD21 gene_id:283219|Hs108|chr11 (260 aa) initn: 303 init1: 209 opt: 298 Z-score: 323.8 bits: 68.3 E(32554): 1e-11 Smith-Waterman score: 298; 45.8% identity (67.3% similar) in 107 aa overlap (27-133:5-107) 10 20 30 40 50 60 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD . :::::..: : .:: :.: :.: ::: : CCDS31 MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMP 10 20 30 70 80 90 100 110 120 pF1KSD TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK : .::.: :::::: .:::::..:: .. ::. : : : :.:::...:. :.. CCDS31 T----KRDSQGNCFIDRDGKVFRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIE 40 50 60 70 80 90 130 140 150 160 170 180 pF1KSD LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG : :.. : : CCDS31 ALQEKEVELSKAEKNAMLNITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCL 100 110 120 130 140 150 428 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:47:47 2016 done: Thu Nov 3 05:47:47 2016 Total Scan time: 3.080 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]