FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1317, 428 aa 1>>>pF1KSDA1317 428 - 428 aa - 428 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9184+/-0.000338; mu= 15.1569+/- 0.021 mean_var=86.1395+/-17.363, 0's: 0 Z-trim(116.4): 75 B-trim: 1368 in 1/54 Lambda= 0.138189 statistics sampled from 27502 (27580) to 27502 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.323), width: 16 Scan time: 8.720 The best scores are: opt bits E(85289) XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 2943 596.5 4.3e-170 XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 2943 596.5 4.3e-170 XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 2943 596.5 4.3e-170 NP_065819 (OMIM: 613423) BTB/POZ domain-containing ( 428) 2943 596.5 4.3e-170 XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 2943 596.5 4.3e-170 XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 304) 1915 391.5 1.6e-108 XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 286) 1908 390.1 4e-108 NP_612453 (OMIM: 610521) BTB/POZ domain-containing ( 325) 599 129.1 1.6e-29 NP_955751 (OMIM: 607947) potassium channel regulat ( 229) 274 64.2 3.9e-10 NP_775876 (OMIM: 607947) potassium channel regulat ( 272) 274 64.3 4.4e-10 NP_001129677 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 233 56.1 1.2e-07 NP_001245150 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 233 56.1 1.2e-07 NP_945342 (OMIM: 181270,613420) BTB/POZ domain-con ( 257) 233 56.1 1.2e-07 XP_016881197 (OMIM: 181270,613420) PREDICTED: BTB/ ( 257) 233 56.1 1.2e-07 NP_001245151 (OMIM: 181270,613420) BTB/POZ domain- ( 265) 233 56.1 1.3e-07 NP_076981 (OMIM: 615240) BTB/POZ domain-containing ( 234) 227 54.9 2.6e-07 XP_011525600 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 227 54.9 3e-07 NP_001123466 (OMIM: 615240) BTB/POZ domain-contain ( 283) 227 54.9 3e-07 NP_001123467 (OMIM: 615240) BTB/POZ domain-contain ( 283) 227 54.9 3e-07 XP_011525599 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 227 54.9 3e-07 XP_016882772 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 227 54.9 3e-07 NP_001136202 (OMIM: 181270,613420) BTB/POZ domain- ( 865) 233 56.4 3.3e-07 NP_061865 (OMIM: 611285) BTB/POZ domain-containing ( 234) 222 53.9 5.2e-07 NP_001161433 (OMIM: 611725,611726) BTB/POZ domain- ( 288) 214 52.3 1.9e-06 NP_694578 (OMIM: 611725,611726) BTB/POZ domain-con ( 289) 214 52.3 1.9e-06 NP_056168 (OMIM: 613422) BTB/POZ domain-containing ( 263) 196 48.7 2.1e-05 XP_011522877 (OMIM: 613422) PREDICTED: BTB/POZ dom ( 226) 192 47.9 3.2e-05 XP_016878595 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 173) 182 45.8 0.0001 XP_016878594 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 175) 182 45.8 0.0001 NP_001304328 (OMIM: 613421) BTB/POZ domain-contain ( 290) 184 46.4 0.00012 NP_114160 (OMIM: 613421) BTB/POZ domain-containing ( 313) 184 46.4 0.00013 NP_001304324 (OMIM: 613421) BTB/POZ domain-contain ( 314) 184 46.4 0.00013 NP_849194 (OMIM: 608947) BTB/POZ domain-containing ( 329) 182 46.0 0.00017 XP_011544085 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 347) 182 46.0 0.00018 NP_001269615 (OMIM: 616386,616398) BTB/POZ domain- ( 220) 176 44.7 0.00028 NP_001269614 (OMIM: 616386,616398) BTB/POZ domain- ( 225) 176 44.7 0.00029 XP_011528679 (OMIM: 616386,616398) PREDICTED: BTB/ ( 249) 176 44.7 0.00031 NP_066960 (OMIM: 191161) BTB/POZ domain-containing ( 316) 177 45.0 0.00033 NP_078957 (OMIM: 616386,616398) BTB/POZ domain-con ( 297) 176 44.8 0.00036 XP_005261801 (OMIM: 616386,616398) PREDICTED: BTB/ ( 315) 176 44.8 0.00038 NP_001269613 (OMIM: 616386,616398) BTB/POZ domain- ( 321) 176 44.8 0.00039 XP_005261800 (OMIM: 616386,616398) PREDICTED: BTB/ ( 328) 176 44.8 0.00039 XP_016880482 (OMIM: 191161) PREDICTED: BTB/POZ dom ( 391) 177 45.0 0.0004 XP_005261799 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 176 44.8 0.00042 XP_005261798 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 176 44.8 0.00042 XP_011528676 (OMIM: 616386,616398) PREDICTED: BTB/ ( 370) 176 44.8 0.00043 NP_001306223 (OMIM: 613272) BTB/POZ domain-contain ( 813) 174 44.6 0.0011 NP_057205 (OMIM: 613272) BTB/POZ domain-containing ( 815) 174 44.6 0.0011 NP_001002914 (OMIM: 609848) BTB/POZ domain-contain ( 232) 160 41.5 0.0027 >>XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa) initn: 2943 init1: 2943 opt: 2943 Z-score: 3174.8 bits: 596.5 E(85289): 4.3e-170 Smith-Waterman score: 2943; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS 370 380 390 400 410 420 pF1KSD ELLRKYHL :::::::: XP_005 ELLRKYHL >>XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa) initn: 2943 init1: 2943 opt: 2943 Z-score: 3174.8 bits: 596.5 E(85289): 4.3e-170 Smith-Waterman score: 2943; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS 370 380 390 400 410 420 pF1KSD ELLRKYHL :::::::: XP_005 ELLRKYHL >>XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa) initn: 2943 init1: 2943 opt: 2943 Z-score: 3174.8 bits: 596.5 E(85289): 4.3e-170 Smith-Waterman score: 2943; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS 370 380 390 400 410 420 pF1KSD ELLRKYHL :::::::: XP_011 ELLRKYHL >>NP_065819 (OMIM: 613423) BTB/POZ domain-containing pro (428 aa) initn: 2943 init1: 2943 opt: 2943 Z-score: 3174.8 bits: 596.5 E(85289): 4.3e-170 Smith-Waterman score: 2943; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS 370 380 390 400 410 420 pF1KSD ELLRKYHL :::::::: NP_065 ELLRKYHL >>XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ domain- (428 aa) initn: 2943 init1: 2943 opt: 2943 Z-score: 3174.8 bits: 596.5 E(85289): 4.3e-170 Smith-Waterman score: 2943; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428) 10 20 30 40 50 60 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS 370 380 390 400 410 420 pF1KSD ELLRKYHL :::::::: XP_006 ELLRKYHL >>XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ domain- (304 aa) initn: 1915 init1: 1915 opt: 1915 Z-score: 2069.3 bits: 391.5 E(85289): 1.6e-108 Smith-Waterman score: 1915; 100.0% identity (100.0% similar) in 278 aa overlap (1-278:1-278) 10 20 30 40 50 60 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE :::::::::::::::::::::::::::::::::::::: XP_011 SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYRCVLYNINLLYKIRASRGGEGRN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR XP_011 SMIS >>XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ domain- (286 aa) initn: 1908 init1: 1908 opt: 1908 Z-score: 2062.2 bits: 390.1 E(85289): 4e-108 Smith-Waterman score: 1908; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE ::::::::::::::::::::::::::::::::::::: XP_011 SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYPLSTVLIAT 250 260 270 280 310 320 330 340 350 360 pF1KSD GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR >>NP_612453 (OMIM: 610521) BTB/POZ domain-containing pro (325 aa) initn: 1086 init1: 515 opt: 599 Z-score: 651.0 bits: 129.1 E(85289): 1.6e-29 Smith-Waterman score: 1033; 56.0% identity (73.5% similar) in 302 aa overlap (17-279:26-325) 10 20 30 40 50 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLL :: : ::..:::::::::: ::. :..:.: ::: NP_612 MALADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD WKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAE :.::. .. ..::.:::::::.:::::::::::::::: :.::::.:::..::.:::: NP_612 WRMFTQQQP--QELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAE 70 80 90 100 110 120 130 140 pF1KSD YFQLPDLVKLL-TPDEIKQSP--------------DEFCHSDF------EDASQGSDTR- ::.::.::. : .:.. .: ::. . : :: :. . NP_612 YFELPELVRRLGAPQQPGPGPPPSRRGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPT 120 130 140 150 160 170 150 160 170 180 190 pF1KSD ---------------ICPPSSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILV . ::. : ..:. :.::.::::: :.::..::::::::: :: : NP_612 LELASRSPSGGAAGPLLTPSQSLDGSRRSGYITIGYRGSYTIGRDAQADAKFRRVARITV 180 190 200 210 220 230 200 210 220 230 240 250 pF1KSD CGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSV ::. ::::::::.:::::::::: :::::::.::::. ::.::: ::: :::::::.:. NP_612 CGKTSLAKEVFGDTLNESRDPDRPPERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTG 240 250 260 270 280 290 260 270 280 290 300 310 pF1KSD TASFINQ--YTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKEGESGTSCNDLST : .: .. ..::::.::::::: :: NP_612 TCAFASSTDQSEDKIWTSYTEYVFCRE 300 310 320 >>NP_955751 (OMIM: 607947) potassium channel regulatory (229 aa) initn: 277 init1: 171 opt: 274 Z-score: 303.0 bits: 64.2 E(85289): 3.9e-10 Smith-Waterman score: 274; 42.7% identity (69.1% similar) in 110 aa overlap (22-131:2-107) 10 20 30 40 50 60 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD : :.: :::::... :: ::. ..: : : .:. : NP_955 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----D 10 20 30 70 80 90 100 110 120 pF1KSD TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK .. : :..:.:::: :: .:::.:: .:..:: .: . ::.::: ...: .:: NP_955 GRDQEFKMVGGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KSD LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG ::.: .. : NP_955 LLNPYLLQPRPALVEVHFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNF 100 110 120 130 140 150 >>NP_775876 (OMIM: 607947) potassium channel regulatory (272 aa) initn: 298 init1: 171 opt: 274 Z-score: 301.9 bits: 64.3 E(85289): 4.4e-10 Smith-Waterman score: 274; 42.7% identity (69.1% similar) in 110 aa overlap (22-131:2-107) 10 20 30 40 50 60 pF1KSD MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD : :.: :::::... :: ::. ..: : : .:. : NP_775 MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----D 10 20 30 70 80 90 100 110 120 pF1KSD TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK .. : :..:.:::: :: .:::.:: .:..:: .: . ::.::: ...: .:: NP_775 GRDQEFKMVGGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KSD LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG ::.: .. : NP_775 LLNPYLLQPRPALVEVHFLSRNTQAFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNF 100 110 120 130 140 150 428 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:47:48 2016 done: Thu Nov 3 05:47:49 2016 Total Scan time: 8.720 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]