Result of FASTA (omim) for pF1KSDA1345
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1345, 1512 aa
  1>>>pF1KSDA1345 1512 - 1512 aa - 1512 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.0413+/-0.00043; mu= 11.1429+/- 0.027
 mean_var=165.3717+/-31.997, 0's: 0 Z-trim(115.6): 28  B-trim: 0 in 0/56
 Lambda= 0.099734
 statistics sampled from 26209 (26233) to 26209 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.308), width:  16
 Scan time: 18.060

The best scores are:                                      opt bits E(85289)
XP_016863971 (OMIM: 216360,612013,612284,612285) P (1571) 7608 1108.3       0
XP_005248234 (OMIM: 216360,612013,612284,612285) P (1620) 7608 1108.3       0
NP_001073991 (OMIM: 216360,612013,612284,612285) c (1620) 7608 1108.3       0
XP_011512174 (OMIM: 216360,612013,612284,612285) P (1013) 6317 922.4       0
NP_001158192 (OMIM: 216360,612013,612284,612285) c ( 111)  220 44.5 0.00058
XP_011512176 (OMIM: 216360,612013,612284,612285) P ( 111)  220 44.5 0.00058


>>XP_016863971 (OMIM: 216360,612013,612284,612285) PREDI  (1571 aa)
 initn: 7748 init1: 7608 opt: 7608  Z-score: 5920.7  bits: 1108.3 E(85289):    0
Smith-Waterman score: 9800; 96.2% identity (96.2% similar) in 1544 aa overlap (1-1485:1-1544)

               10        20        30        40        50        60
pF1KSD MVSEKSHLGNPQEPVQEEPKTRLLSMTVRRGPRSLPPIPSTSRTGFAEFSMRGRMREKLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVSEKSHLGNPQEPVQEEPKTRLLSMTVRRGPRSLPPIPSTSRTGFAEFSMRGRMREKLQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD AARSKAESALLQEIPTPRPRRLRSPSKKELETEFGTEPGKEVERTQQEVDSQSYSRVKFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARSKAESALLQEIPTPRPRRLRSPSKKELETEFGTEPGKEVERTQQEVDSQSYSRVKFH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD DSARKIKPKPQVPPGFPSAEEAYNFFTFNFDPEPEGSEEKPKARHRAGTNQEEEEGEEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSARKIKPKPQVPPGFPSAEEAYNFFTFNFDPEPEGSEEKPKARHRAGTNQEEEEGEEEE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD PPAQGGGKEMDEEELLNGDDAEDFLLGLDHVADDFVAVRPADYESIHDRLQMEREMLFIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPAQGGGKEMDEEELLNGDDAEDFLLGLDHVADDFVAVRPADYESIHDRLQMEREMLFIP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SRQTVPTYKKLPENVQPRFLEDEGLYTGVRPEVARTNQNIMENRLLMQDPERRWFGDDGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRQTVPTYKKLPENVQPRFLEDEGLYTGVRPEVARTNQNIMENRLLMQDPERRWFGDDGR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD ILALPNPIKPFPSRPPVLTQEQSIKAELETLYKKAVKYVHSSQHVIRSGDPPGNFQLDID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILALPNPIKPFPSRPPVLTQEQSIKAELETLYKKAVKYVHSSQHVIRSGDPPGNFQLDID
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD ISGLIFTHHPCFSREHVLAAKLAQLYDQYLARHQRNKAKFLTDKLQALRNAVQTGLDPEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISGLIFTHHPCFSREHVLAAKLAQLYDQYLARHQRNKAKFLTDKLQALRNAVQTGLDPEK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD PHQSLDTIQKTINEYKSEIRQTRKFRDAEQEKDRTLLKTIIKVWKEMKSLREFQRFTNTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHQSLDTIQKTINEYKSEIRQTRKFRDAEQEKDRTLLKTIIKVWKEMKSLREFQRFTNTP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD LKLVLRKEKADQKADEEAYEAEIQAEISELLEEHTEEYAQKMEEYRTSLQQWKAWRKVQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLVLRKEKADQKADEEAYEAEIQAEISELLEEHTEEYAQKMEEYRTSLQQWKAWRKVQR
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD AKKKKRKQAAEEHPGDEIAEPYPEEDLVKPSPPEPTDRAVIEQEVRERAAQSRRRPWEPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKKKRKQAAEEHPGDEIAEPYPEEDLVKPSPPEPTDRAVIEQEVRERAAQSRRRPWEPT
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD LVPELSLAGSVTPNDQCPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGADFRVHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVPELSLAGSVTPNDQCPRAEVSRREDVKKRSVYLKVLFNNKEVSRTVSRPLGADFRVHF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD GQIFNLQIVNWPESLTLQVYETVGHSSPTLLAEVFLPIPETTVVTGRAPTEEVEFSSNQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQIFNLQIVNWPESLTLQVYETVGHSSPTLLAEVFLPIPETTVVTGRAPTEEVEFSSNQH
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD VTLDHEGVGSGVPFSFEADGSNQLTLMTSGKVSHSVAWAIGENGIPLIPPLSQQNIGFRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLDHEGVGSGVPFSFEADGSNQLTLMTSGKVSHSVAWAIGENGIPLIPPLSQQNIGFRS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD ALKKADAISSIGTSGLTDMKKLAKWAAESKLDPNDPNNAPLMQLISVATSGESYVPDFFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKKADAISSIGTSGLTDMKKLAKWAAESKLDPNDPNNAPLMQLISVATSGESYVPDFFR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD LEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVPVYDREIMEKVFQDYEKRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQLQQEFNFVSDQELNRSKRFRLLHLRSQEVPEFRNYKQVPVYDREIMEKVFQDYEKRL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD RDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFLLADMIVEEEVPNISILGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDRNVIETKEHIDTHRAIVAKYLQQVRESVINRFLIAKQYFLLADMIVEEEVPNISILGL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD SLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSKFQQPSRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLFKLAEQKRPLRPRRKGRKKVTAQNLSDGDIKLLVNIVRAYDIPVRKPAVSKFQQPSRS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD SRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRMFSEKHAASPSTYSPTHNADYPLGQVLVRPFVEVSFQRTVCHTTTAEGPNPSWNEELE
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD LPFRAPNGDYSTASLQSVKDVVFINIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPFRAPNGDYSTASLQSVKDVVFINIFDEVLHDVLEDDRERGSGIHTRIERHWLGCVKMP
             1090      1100      1110      1120      1130      1140

                                                                   
pF1KSD FSTIYFQAR---------------------------------------------------
       :::::::::                                                   
XP_016 FSTIYFQARIDGTFKIDIPPVLLGYSKERNMILERGFDSVRSLSEGSYITLFITIEPQLV
             1150      1160      1170      1180      1190      1200

            1150      1160      1170      1180      1190      1200 
pF1KSD --------FESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNP
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGESIREKFESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNP
             1210      1220      1230      1240      1250      1260

            1210      1220      1230      1240      1250      1260 
pF1KSD PQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHA
             1270      1280      1290      1300      1310      1320

            1270      1280      1290      1300      1310      1320 
pF1KSD VLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKN
             1330      1340      1350      1360      1370      1380

            1330      1340      1350      1360      1370      1380 
pF1KSD VGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQPEELIYQRSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQPEELIYQRSD
             1390      1400      1410      1420      1430      1440

            1390      1400      1410      1420      1430      1440 
pF1KSD KAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAE
             1450      1460      1470      1480      1490      1500

            1450      1460      1470      1480      1490      1500 
pF1KSD LLKQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSV
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_016 LLKQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSV
             1510      1520      1530      1540      1550      1560

            1510  
pF1KSD WIYVASLIRNR
                  
XP_016 WIYVASLIRNR
             1570 

>>XP_005248234 (OMIM: 216360,612013,612284,612285) PREDI  (1620 aa)
 initn: 7748 init1: 7608 opt: 7608  Z-score: 5920.5  bits: 1108.3 E(85289):    0
Smith-Waterman score: 9800; 96.2% identity (96.2% similar) in 1544 aa overlap (1-1485:50-1593)

                                             10        20        30
pF1KSD                               MVSEKSHLGNPQEPVQEEPKTRLLSMTVRR
                                     ::::::::::::::::::::::::::::::
XP_005 EDADMGRQNKNSKVRRQPRKKQPPTAVPKEMVSEKSHLGNPQEPVQEEPKTRLLSMTVRR
      20        30        40        50        60        70         

               40        50        60        70        80        90
pF1KSD GPRSLPPIPSTSRTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRRLRSPSKKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPRSLPPIPSTSRTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRRLRSPSKKEL
      80        90       100       110       120       130         

              100       110       120       130       140       150
pF1KSD ETEFGTEPGKEVERTQQEVDSQSYSRVKFHDSARKIKPKPQVPPGFPSAEEAYNFFTFNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETEFGTEPGKEVERTQQEVDSQSYSRVKFHDSARKIKPKPQVPPGFPSAEEAYNFFTFNF
     140       150       160       170       180       190         

              160       170       180       190       200       210
pF1KSD DPEPEGSEEKPKARHRAGTNQEEEEGEEEEPPAQGGGKEMDEEELLNGDDAEDFLLGLDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPEPEGSEEKPKARHRAGTNQEEEEGEEEEPPAQGGGKEMDEEELLNGDDAEDFLLGLDH
     200       210       220       230       240       250         

              220       230       240       250       260       270
pF1KSD VADDFVAVRPADYESIHDRLQMEREMLFIPSRQTVPTYKKLPENVQPRFLEDEGLYTGVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VADDFVAVRPADYESIHDRLQMEREMLFIPSRQTVPTYKKLPENVQPRFLEDEGLYTGVR
     260       270       280       290       300       310         

              280       290       300       310       320       330
pF1KSD PEVARTNQNIMENRLLMQDPERRWFGDDGRILALPNPIKPFPSRPPVLTQEQSIKAELET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEVARTNQNIMENRLLMQDPERRWFGDDGRILALPNPIKPFPSRPPVLTQEQSIKAELET
     320       330       340       350       360       370         

              340       350       360       370       380       390
pF1KSD LYKKAVKYVHSSQHVIRSGDPPGNFQLDIDISGLIFTHHPCFSREHVLAAKLAQLYDQYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYKKAVKYVHSSQHVIRSGDPPGNFQLDIDISGLIFTHHPCFSREHVLAAKLAQLYDQYL
     380       390       400       410       420       430         

              400       410       420       430       440       450
pF1KSD ARHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQTRKFRDAEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQTRKFRDAEQ
     440       450       460       470       480       490         

              460       470       480       490       500       510
pF1KSD EKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKEKADQKADEEAYEAEIQAEISEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKEKADQKADEEAYEAEIQAEISEL
     500       510       520       530       540       550         

              520       530       540       550       560       570
pF1KSD LEEHTEEYAQKMEEYRTSLQQWKAWRKVQRAKKKKRKQAAEEHPGDEIAEPYPEEDLVKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEEHTEEYAQKMEEYRTSLQQWKAWRKVQRAKKKKRKQAAEEHPGDEIAEPYPEEDLVKP
     560       570       580       590       600       610         

              580       590       600       610       620       630
pF1KSD SPPEPTDRAVIEQEVRERAAQSRRRPWEPTLVPELSLAGSVTPNDQCPRAEVSRREDVKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPPEPTDRAVIEQEVRERAAQSRRRPWEPTLVPELSLAGSVTPNDQCPRAEVSRREDVKK
     620       630       640       650       660       670         

              640       650       660       670       680       690
pF1KSD RSVYLKVLFNNKEVSRTVSRPLGADFRVHFGQIFNLQIVNWPESLTLQVYETVGHSSPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSVYLKVLFNNKEVSRTVSRPLGADFRVHFGQIFNLQIVNWPESLTLQVYETVGHSSPTL
     680       690       700       710       720       730         

              700       710       720       730       740       750
pF1KSD LAEVFLPIPETTVVTGRAPTEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAEVFLPIPETTVVTGRAPTEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSG
     740       750       760       770       780       790         

              760       770       780       790       800       810
pF1KSD KVSHSVAWAIGENGIPLIPPLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVSHSVAWAIGENGIPLIPPLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESK
     800       810       820       830       840       850         

              820       830       840       850       860       870
pF1KSD LDPNDPNNAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDPNDPNNAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQ
     860       870       880       890       900       910         

              880       890       900       910       920       930
pF1KSD EVPEFRNYKQVPVYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVPEFRNYKQVPVYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESV
     920       930       940       950       960       970         

              940       950       960       970       980       990
pF1KSD INRFLIAKQYFLLADMIVEEEVPNISILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INRFLIAKQYFLLADMIVEEEVPNISILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDG
     980       990      1000      1010      1020      1030         

             1000      1010      1020      1030      1040      1050
pF1KSD DIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLV
    1040      1050      1060      1070      1080      1090         

             1060      1070      1080      1090      1100      1110
pF1KSD RPFVEVSFQRTVCHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVFINIFDEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPFVEVSFQRTVCHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVFINIFDEV
    1100      1110      1120      1130      1140      1150         

             1120      1130      1140                              
pF1KSD LHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQAR---------------------
       :::::::::::::::::::::::::::::::::::::::                     
XP_005 LHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARIDGTFKIDIPPVLLGYSKERN
    1160      1170      1180      1190      1200      1210         

                                          1150      1160      1170 
pF1KSD --------------------------------------FESQEDEKLLQATEKFQAECAL
                                             ::::::::::::::::::::::
XP_005 MILERGFDSVRSLSEGSYITLFITIEPQLVPGESIREKFESQEDEKLLQATEKFQAECAL
    1220      1230      1240      1250      1260      1270         

            1180      1190      1200      1210      1220      1230 
pF1KSD KFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLP
    1280      1290      1300      1310      1320      1330         

            1240      1250      1260      1270      1280      1290 
pF1KSD DTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYV
    1340      1350      1360      1370      1380      1390         

            1300      1310      1320      1330      1340      1350 
pF1KSD LTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRP
    1400      1410      1420      1430      1440      1450         

            1360      1370      1380      1390      1400      1410 
pF1KSD KLWKSFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLWKSFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRW
    1460      1470      1480      1490      1500      1510         

            1420      1430      1440      1450      1460      1470 
pF1KSD NRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIDAVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIDAVY
    1520      1530      1540      1550      1560      1570         

            1480      1490      1500      1510  
pF1KSD STGVHNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRNR
       ::::::::::::::                           
XP_005 STGVHNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRNR
    1580      1590      1600      1610      1620

>>NP_001073991 (OMIM: 216360,612013,612284,612285) coile  (1620 aa)
 initn: 7748 init1: 7608 opt: 7608  Z-score: 5920.5  bits: 1108.3 E(85289):    0
Smith-Waterman score: 9800; 96.2% identity (96.2% similar) in 1544 aa overlap (1-1485:50-1593)

                                             10        20        30
pF1KSD                               MVSEKSHLGNPQEPVQEEPKTRLLSMTVRR
                                     ::::::::::::::::::::::::::::::
NP_001 EDADMGRQNKNSKVRRQPRKKQPPTAVPKEMVSEKSHLGNPQEPVQEEPKTRLLSMTVRR
      20        30        40        50        60        70         

               40        50        60        70        80        90
pF1KSD GPRSLPPIPSTSRTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRRLRSPSKKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPRSLPPIPSTSRTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRRLRSPSKKEL
      80        90       100       110       120       130         

              100       110       120       130       140       150
pF1KSD ETEFGTEPGKEVERTQQEVDSQSYSRVKFHDSARKIKPKPQVPPGFPSAEEAYNFFTFNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETEFGTEPGKEVERTQQEVDSQSYSRVKFHDSARKIKPKPQVPPGFPSAEEAYNFFTFNF
     140       150       160       170       180       190         

              160       170       180       190       200       210
pF1KSD DPEPEGSEEKPKARHRAGTNQEEEEGEEEEPPAQGGGKEMDEEELLNGDDAEDFLLGLDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPEPEGSEEKPKARHRAGTNQEEEEGEEEEPPAQGGGKEMDEEELLNGDDAEDFLLGLDH
     200       210       220       230       240       250         

              220       230       240       250       260       270
pF1KSD VADDFVAVRPADYESIHDRLQMEREMLFIPSRQTVPTYKKLPENVQPRFLEDEGLYTGVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VADDFVAVRPADYESIHDRLQMEREMLFIPSRQTVPTYKKLPENVQPRFLEDEGLYTGVR
     260       270       280       290       300       310         

              280       290       300       310       320       330
pF1KSD PEVARTNQNIMENRLLMQDPERRWFGDDGRILALPNPIKPFPSRPPVLTQEQSIKAELET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEVARTNQNIMENRLLMQDPERRWFGDDGRILALPNPIKPFPSRPPVLTQEQSIKAELET
     320       330       340       350       360       370         

              340       350       360       370       380       390
pF1KSD LYKKAVKYVHSSQHVIRSGDPPGNFQLDIDISGLIFTHHPCFSREHVLAAKLAQLYDQYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYKKAVKYVHSSQHVIRSGDPPGNFQLDIDISGLIFTHHPCFSREHVLAAKLAQLYDQYL
     380       390       400       410       420       430         

              400       410       420       430       440       450
pF1KSD ARHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQTRKFRDAEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQTRKFRDAEQ
     440       450       460       470       480       490         

              460       470       480       490       500       510
pF1KSD EKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKEKADQKADEEAYEAEIQAEISEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKEKADQKADEEAYEAEIQAEISEL
     500       510       520       530       540       550         

              520       530       540       550       560       570
pF1KSD LEEHTEEYAQKMEEYRTSLQQWKAWRKVQRAKKKKRKQAAEEHPGDEIAEPYPEEDLVKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEHTEEYAQKMEEYRTSLQQWKAWRKVQRAKKKKRKQAAEEHPGDEIAEPYPEEDLVKP
     560       570       580       590       600       610         

              580       590       600       610       620       630
pF1KSD SPPEPTDRAVIEQEVRERAAQSRRRPWEPTLVPELSLAGSVTPNDQCPRAEVSRREDVKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPPEPTDRAVIEQEVRERAAQSRRRPWEPTLVPELSLAGSVTPNDQCPRAEVSRREDVKK
     620       630       640       650       660       670         

              640       650       660       670       680       690
pF1KSD RSVYLKVLFNNKEVSRTVSRPLGADFRVHFGQIFNLQIVNWPESLTLQVYETVGHSSPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSVYLKVLFNNKEVSRTVSRPLGADFRVHFGQIFNLQIVNWPESLTLQVYETVGHSSPTL
     680       690       700       710       720       730         

              700       710       720       730       740       750
pF1KSD LAEVFLPIPETTVVTGRAPTEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAEVFLPIPETTVVTGRAPTEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSG
     740       750       760       770       780       790         

              760       770       780       790       800       810
pF1KSD KVSHSVAWAIGENGIPLIPPLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVSHSVAWAIGENGIPLIPPLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESK
     800       810       820       830       840       850         

              820       830       840       850       860       870
pF1KSD LDPNDPNNAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDPNDPNNAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQ
     860       870       880       890       900       910         

              880       890       900       910       920       930
pF1KSD EVPEFRNYKQVPVYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVPEFRNYKQVPVYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESV
     920       930       940       950       960       970         

              940       950       960       970       980       990
pF1KSD INRFLIAKQYFLLADMIVEEEVPNISILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INRFLIAKQYFLLADMIVEEEVPNISILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDG
     980       990      1000      1010      1020      1030         

             1000      1010      1020      1030      1040      1050
pF1KSD DIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIKLLVNIVRAYDIPVRKPAVSKFQQPSRSSRMFSEKHAASPSTYSPTHNADYPLGQVLV
    1040      1050      1060      1070      1080      1090         

             1060      1070      1080      1090      1100      1110
pF1KSD RPFVEVSFQRTVCHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVFINIFDEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPFVEVSFQRTVCHTTTAEGPNPSWNEELELPFRAPNGDYSTASLQSVKDVVFINIFDEV
    1100      1110      1120      1130      1140      1150         

             1120      1130      1140                              
pF1KSD LHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQAR---------------------
       :::::::::::::::::::::::::::::::::::::::                     
NP_001 LHDVLEDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARIDGTFKIDIPPVLLGYSKERN
    1160      1170      1180      1190      1200      1210         

                                          1150      1160      1170 
pF1KSD --------------------------------------FESQEDEKLLQATEKFQAECAL
                                             ::::::::::::::::::::::
NP_001 MILERGFDSVRSLSEGSYITLFITIEPQLVPGESIREKFESQEDEKLLQATEKFQAECAL
    1220      1230      1240      1250      1260      1270         

            1180      1190      1200      1210      1220      1230 
pF1KSD KFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFPNRQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLP
    1280      1290      1300      1310      1320      1330         

            1240      1250      1260      1270      1280      1290 
pF1KSD DTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTVSFGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYV
    1340      1350      1360      1370      1380      1390         

            1300      1310      1320      1330      1340      1350 
pF1KSD LTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTWEQGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRP
    1400      1410      1420      1430      1440      1450         

            1360      1370      1380      1390      1400      1410 
pF1KSD KLWKSFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLWKSFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRW
    1460      1470      1480      1490      1500      1510         

            1420      1430      1440      1450      1460      1470 
pF1KSD NRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIDAVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRYCTSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIDAVY
    1520      1530      1540      1550      1560      1570         

            1480      1490      1500      1510  
pF1KSD STGVHNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRNR
       ::::::::::::::                           
NP_001 STGVHNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRNR
    1580      1590      1600      1610      1620

>>XP_011512174 (OMIM: 216360,612013,612284,612285) PREDI  (1013 aa)
 initn: 6545 init1: 6317 opt: 6317  Z-score: 4919.5  bits: 922.4 E(85289):    0
Smith-Waterman score: 6317; 99.7% identity (99.8% similar) in 960 aa overlap (1-960:50-1009)

                                             10        20        30
pF1KSD                               MVSEKSHLGNPQEPVQEEPKTRLLSMTVRR
                                     ::::::::::::::::::::::::::::::
XP_011 EDADMGRQNKNSKVRRQPRKKQPPTAVPKEMVSEKSHLGNPQEPVQEEPKTRLLSMTVRR
      20        30        40        50        60        70         

               40        50        60        70        80        90
pF1KSD GPRSLPPIPSTSRTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRRLRSPSKKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPRSLPPIPSTSRTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRRLRSPSKKEL
      80        90       100       110       120       130         

              100       110       120       130       140       150
pF1KSD ETEFGTEPGKEVERTQQEVDSQSYSRVKFHDSARKIKPKPQVPPGFPSAEEAYNFFTFNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEFGTEPGKEVERTQQEVDSQSYSRVKFHDSARKIKPKPQVPPGFPSAEEAYNFFTFNF
     140       150       160       170       180       190         

              160       170       180       190       200       210
pF1KSD DPEPEGSEEKPKARHRAGTNQEEEEGEEEEPPAQGGGKEMDEEELLNGDDAEDFLLGLDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPEPEGSEEKPKARHRAGTNQEEEEGEEEEPPAQGGGKEMDEEELLNGDDAEDFLLGLDH
     200       210       220       230       240       250         

              220       230       240       250       260       270
pF1KSD VADDFVAVRPADYESIHDRLQMEREMLFIPSRQTVPTYKKLPENVQPRFLEDEGLYTGVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VADDFVAVRPADYESIHDRLQMEREMLFIPSRQTVPTYKKLPENVQPRFLEDEGLYTGVR
     260       270       280       290       300       310         

              280       290       300       310       320       330
pF1KSD PEVARTNQNIMENRLLMQDPERRWFGDDGRILALPNPIKPFPSRPPVLTQEQSIKAELET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEVARTNQNIMENRLLMQDPERRWFGDDGRILALPNPIKPFPSRPPVLTQEQSIKAELET
     320       330       340       350       360       370         

              340       350       360       370       380       390
pF1KSD LYKKAVKYVHSSQHVIRSGDPPGNFQLDIDISGLIFTHHPCFSREHVLAAKLAQLYDQYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYKKAVKYVHSSQHVIRSGDPPGNFQLDIDISGLIFTHHPCFSREHVLAAKLAQLYDQYL
     380       390       400       410       420       430         

              400       410       420       430       440       450
pF1KSD ARHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQTRKFRDAEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARHQRNKAKFLTDKLQALRNAVQTGLDPEKPHQSLDTIQKTINEYKSEIRQTRKFRDAEQ
     440       450       460       470       480       490         

              460       470       480       490       500       510
pF1KSD EKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKEKADQKADEEAYEAEIQAEISEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKDRTLLKTIIKVWKEMKSLREFQRFTNTPLKLVLRKEKADQKADEEAYEAEIQAEISEL
     500       510       520       530       540       550         

              520       530       540       550       560       570
pF1KSD LEEHTEEYAQKMEEYRTSLQQWKAWRKVQRAKKKKRKQAAEEHPGDEIAEPYPEEDLVKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEEHTEEYAQKMEEYRTSLQQWKAWRKVQRAKKKKRKQAAEEHPGDEIAEPYPEEDLVKP
     560       570       580       590       600       610         

              580       590       600       610       620       630
pF1KSD SPPEPTDRAVIEQEVRERAAQSRRRPWEPTLVPELSLAGSVTPNDQCPRAEVSRREDVKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPEPTDRAVIEQEVRERAAQSRRRPWEPTLVPELSLAGSVTPNDQCPRAEVSRREDVKK
     620       630       640       650       660       670         

              640       650       660       670       680       690
pF1KSD RSVYLKVLFNNKEVSRTVSRPLGADFRVHFGQIFNLQIVNWPESLTLQVYETVGHSSPTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSVYLKVLFNNKEVSRTVSRPLGADFRVHFGQIFNLQIVNWPESLTLQVYETVGHSSPTL
     680       690       700       710       720       730         

              700       710       720       730       740       750
pF1KSD LAEVFLPIPETTVVTGRAPTEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAEVFLPIPETTVVTGRAPTEEVEFSSNQHVTLDHEGVGSGVPFSFEADGSNQLTLMTSG
     740       750       760       770       780       790         

              760       770       780       790       800       810
pF1KSD KVSHSVAWAIGENGIPLIPPLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVSHSVAWAIGENGIPLIPPLSQQNIGFRSALKKADAISSIGTSGLTDMKKLAKWAAESK
     800       810       820       830       840       850         

              820       830       840       850       860       870
pF1KSD LDPNDPNNAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDPNDPNNAPLMQLISVATSGESYVPDFFRLEQLQQEFNFVSDQELNRSKRFRLLHLRSQ
     860       870       880       890       900       910         

              880       890       900       910       920       930
pF1KSD EVPEFRNYKQVPVYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVPEFRNYKQVPVYDREIMEKVFQDYEKRLRDRNVIETKEHIDTHRAIVAKYLQQVRESV
     920       930       940       950       960       970         

              940       950       960       970       980       990
pF1KSD INRFLIAKQYFLLADMIVEEEVPNISILGLSLFKLAEQKRPLRPRRKGRKKVTAQNLSDG
       ::::::::::::::::::::::::: .: :                              
XP_011 INRFLIAKQYFLLADMIVEEEVPNIRVLILFCNH                          
     980       990      1000      1010                             

>>NP_001158192 (OMIM: 216360,612013,612284,612285) coile  (111 aa)
 initn: 243 init1: 220 opt: 220  Z-score: 192.2  bits: 44.5 E(85289): 0.00058
Smith-Waterman score: 220; 100.0% identity (100.0% similar) in 33 aa overlap (1-33:50-82)

                                             10        20        30
pF1KSD                               MVSEKSHLGNPQEPVQEEPKTRLLSMTVRR
                                     ::::::::::::::::::::::::::::::
NP_001 EDADMGRQNKNSKVRRQPRKKQPPTAVPKEMVSEKSHLGNPQEPVQEEPKTRLLSMTVRR
      20        30        40        50        60        70         

               40        50        60        70        80        90
pF1KSD GPRSLPPIPSTSRTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRRLRSPSKKEL
       :::                                                         
NP_001 GPRRELVVKKSLGRPGTVTHVCNPSTLEGRGG                            
      80        90       100       110                             

>>XP_011512176 (OMIM: 216360,612013,612284,612285) PREDI  (111 aa)
 initn: 243 init1: 220 opt: 220  Z-score: 192.2  bits: 44.5 E(85289): 0.00058
Smith-Waterman score: 220; 100.0% identity (100.0% similar) in 33 aa overlap (1-33:50-82)

                                             10        20        30
pF1KSD                               MVSEKSHLGNPQEPVQEEPKTRLLSMTVRR
                                     ::::::::::::::::::::::::::::::
XP_011 EDADMGRQNKNSKVRRQPRKKQPPTAVPKEMVSEKSHLGNPQEPVQEEPKTRLLSMTVRR
      20        30        40        50        60        70         

               40        50        60        70        80        90
pF1KSD GPRSLPPIPSTSRTGFAEFSMRGRMREKLQAARSKAESALLQEIPTPRPRRLRSPSKKEL
       :::                                                         
XP_011 GPRRELVVKKSLGRPGTVTHVCNPSTLEGRGG                            
      80        90       100       110                             




1512 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 05:54:50 2016 done: Thu Nov  3 05:54:53 2016
 Total Scan time: 18.060 Total Display time:  0.300

Function used was FASTA [36.3.4 Apr, 2011]
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