FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1363, 408 aa 1>>>pF1KSDA1363 408 - 408 aa - 408 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9990+/-0.000405; mu= 18.3871+/- 0.025 mean_var=61.0105+/-12.539, 0's: 0 Z-trim(111.8): 64 B-trim: 310 in 2/49 Lambda= 0.164200 statistics sampled from 20425 (20488) to 20425 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.24), width: 16 Scan time: 8.170 The best scores are: opt bits E(85289) NP_065843 (OMIM: 613234) neutral cholesterol ester ( 440) 2695 647.2 2.3e-185 NP_001139748 (OMIM: 613234) neutral cholesterol es ( 448) 2664 639.9 3.8e-183 NP_001139750 (OMIM: 613234) neutral cholesterol es ( 275) 1817 439.1 6.3e-123 NP_001139749 (OMIM: 613234) neutral cholesterol es ( 275) 1817 439.1 6.3e-123 NP_001077 (OMIM: 600338) arylacetamide deacetylase ( 399) 1132 276.9 6.1e-74 XP_005247161 (OMIM: 600338) PREDICTED: arylacetami ( 382) 1000 245.6 1.5e-64 XP_005258997 (OMIM: 151750,615980) PREDICTED: horm ( 775) 165 48.0 9.5e-05 XP_006723281 (OMIM: 151750,615980) PREDICTED: horm ( 775) 165 48.0 9.5e-05 XP_016882299 (OMIM: 151750,615980) PREDICTED: horm ( 775) 165 48.0 9.5e-05 XP_005258995 (OMIM: 151750,615980) PREDICTED: horm ( 821) 165 48.0 0.0001 XP_005258996 (OMIM: 151750,615980) PREDICTED: horm ( 838) 165 48.0 0.0001 XP_005258994 (OMIM: 151750,615980) PREDICTED: horm (1000) 165 48.1 0.00012 NP_005348 (OMIM: 151750,615980) hormone-sensitive (1076) 165 48.1 0.00012 >>NP_065843 (OMIM: 613234) neutral cholesterol ester hyd (440 aa) initn: 2695 init1: 2695 opt: 2695 Z-score: 3448.9 bits: 647.2 E(85289): 2.3e-185 Smith-Waterman score: 2695; 99.8% identity (100.0% similar) in 408 aa overlap (1-408:33-440) 10 20 30 pF1KSD MRSSCVLLTALVALATYYVYIPLPGSVSDP :::::::::::::::.:::::::::::::: NP_065 SCRGQKVAGGLRVVSPFPLCQPAGEPSQGKMRSSCVLLTALVALAAYYVYIPLPGSVSDP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD WKLMLLDATFRGAQQVSNLIHYLGLSHHLLALNFIIVSFGKKSAWSSAQVKVTDTDFDGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 WKLMLLDATFRGAQQVSNLIHYLGLSHHLLALNFIIVSFGKKSAWSSAQVKVTDTDFDGV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KSD EVRVFEGPPKPEEPLKRSVVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EVRVFEGPPKPEEPLKRSVVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KSD PKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFTQDASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFTQDASL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KSD KNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDFVQAMIVNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 KNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDFVQAMIVNN 250 260 270 280 290 300 280 290 300 310 320 330 pF1KSD HTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARSAPLIAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 HTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARSAPLIAD 310 320 330 340 350 360 340 350 360 370 380 390 pF1KSD QAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMIFTSWPTNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMIFTSWPTNF 370 380 390 400 410 420 400 pF1KSD SVGIRTRNSYIKWLDQNL :::::::::::::::::: NP_065 SVGIRTRNSYIKWLDQNL 430 440 >>NP_001139748 (OMIM: 613234) neutral cholesterol ester (448 aa) initn: 1891 init1: 1891 opt: 2664 Z-score: 3409.1 bits: 639.9 E(85289): 3.8e-183 Smith-Waterman score: 2664; 97.6% identity (98.1% similar) in 416 aa overlap (1-408:33-448) 10 20 30 pF1KSD MRSSCVLLTALVALATYYVYIPLPGSVSDP :::::::::::::::.:::::::::::::: NP_001 SCRGQKVAGGLRVVSPFPLCQPAGEPSQGKMRSSCVLLTALVALAAYYVYIPLPGSVSDP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KSD WKLMLLDATFRGAQQVSNLIHYLGLSHHLLALNFIIVSFGKKSAWSSAQVKVTDTDFDGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WKLMLLDATFRGAQQVSNLIHYLGLSHHLLALNFIIVSFGKKSAWSSAQVKVTDTDFDGV 70 80 90 100 110 120 100 110 120 130 140 pF1KSD EVRVFEGPPKPEEPLKRSVVYIHGGGWALASA--------KIRYYDELCTAMAEELNAVI :::::::::::::::::::::::::::::::: .::::::::::::::::::: NP_001 EVRVFEGPPKPEEPLKRSVVYIHGGGWALASASASWSPSDEIRYYDELCTAMAEELNAVI 130 140 150 160 170 180 150 160 170 180 190 200 pF1KSD VSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQ 190 200 210 220 230 240 210 220 230 240 250 260 pF1KSD QFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDF 250 260 270 280 290 300 270 280 290 300 310 320 pF1KSD VQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDA 310 320 330 340 350 360 330 340 350 360 370 380 pF1KSD RSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMI 370 380 390 400 410 420 390 400 pF1KSD FTSWPTNFSVGIRTRNSYIKWLDQNL :::::::::::::::::::::::::: NP_001 FTSWPTNFSVGIRTRNSYIKWLDQNL 430 440 >>NP_001139750 (OMIM: 613234) neutral cholesterol ester (275 aa) initn: 1817 init1: 1817 opt: 1817 Z-score: 2327.9 bits: 439.1 E(85289): 6.3e-123 Smith-Waterman score: 1817; 100.0% identity (100.0% similar) in 275 aa overlap (134-408:1-275) 110 120 130 140 150 160 pF1KSD PLKRSVVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVV :::::::::::::::::::::::::::::: NP_001 MAEELNAVIVSIEYRLVPKVYFPEQIHDVV 10 20 30 170 180 190 200 210 220 pF1KSD RATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPV 40 50 60 70 80 90 230 240 250 260 270 280 pF1KSD LQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVR 100 110 120 130 140 150 290 300 310 320 330 340 pF1KSD ARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYIL 160 170 180 190 200 210 350 360 370 380 390 400 pF1KSD TCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKW 220 230 240 250 260 270 pF1KSD LDQNL ::::: NP_001 LDQNL >>NP_001139749 (OMIM: 613234) neutral cholesterol ester (275 aa) initn: 1817 init1: 1817 opt: 1817 Z-score: 2327.9 bits: 439.1 E(85289): 6.3e-123 Smith-Waterman score: 1817; 100.0% identity (100.0% similar) in 275 aa overlap (134-408:1-275) 110 120 130 140 150 160 pF1KSD PLKRSVVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVV :::::::::::::::::::::::::::::: NP_001 MAEELNAVIVSIEYRLVPKVYFPEQIHDVV 10 20 30 170 180 190 200 210 220 pF1KSD RATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPV 40 50 60 70 80 90 230 240 250 260 270 280 pF1KSD LQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVR 100 110 120 130 140 150 290 300 310 320 330 340 pF1KSD ARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYIL 160 170 180 190 200 210 350 360 370 380 390 400 pF1KSD TCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKW 220 230 240 250 260 270 pF1KSD LDQNL ::::: NP_001 LDQNL >>NP_001077 (OMIM: 600338) arylacetamide deacetylase [Ho (399 aa) initn: 1049 init1: 552 opt: 1132 Z-score: 1448.5 bits: 276.9 E(85289): 6.1e-74 Smith-Waterman score: 1132; 43.2% identity (72.5% similar) in 407 aa overlap (2-408:3-399) 10 20 30 40 50 pF1KSD MRSSCVLLTALVALATYYVYIPLPGSVSDPWKLMLLDATFRGAQQVSNLIHYLGLSHHL :.: :: . . .: ::.: ::: .: .::..: ..: .. :....... ::: ::. NP_001 MGRKSLYLLIVGILIA-YYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGL-HHF 10 20 30 40 50 60 70 80 90 100 110 pF1KSD LALNFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRSVVYIHGGGWAL . .. :: . :. .: ::.: :... :::. : . : :.:.. ::::::: . NP_001 MDSFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYV-PKRKSEALRRGLFYIHGGGWCV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KSD ASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYM .:: . :: : :..:.::.:: .:::.:: .:: :..:: : ..::. .:: :: NP_001 GSAALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD VDPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVN :.: :: :::::::::::::. ::. .: ..: :::.:.::::.:: :: . ::::.: : NP_001 VNPERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD TPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKN .: . .::..: .:: . .. .::. .:. . :.. . .::.:::: : :. NP_001 FLFLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPV---ESSHLFKFVNWSSLLPERFIKG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD YKPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAK . . :....... : .::.:.:::.::. :. :: ::..::..:.:::::.::. NP_001 HVYNNPNYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVT 300 310 320 330 340 350 360 370 380 390 400 pF1KSD RLESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKWLDQNL ::...::.:: .: :::::: . : ..... : :.::.:: .:: NP_001 RLRNTGVQVTHNHVEDGFHGAFSFL----GLKISHRLINQYIEWLKENL 360 370 380 390 >>XP_005247161 (OMIM: 600338) PREDICTED: arylacetamide d (382 aa) initn: 1010 init1: 552 opt: 1000 Z-score: 1279.8 bits: 245.6 E(85289): 1.5e-64 Smith-Waterman score: 1071; 42.3% identity (69.5% similar) in 407 aa overlap (2-408:3-382) 10 20 30 40 50 pF1KSD MRSSCVLLTALVALATYYVYIPLPGSVSDPWKLMLLDATFRGAQQVSNLIHYLGLSHHL :.: :: . . .: ::.: ::: .: .::..: ..: .. : XP_005 MGRKSLYLLIVGILIA-YYIYTPLPDNVEEPWRMMWINAHLKTIQ--------------- 10 20 30 40 60 70 80 90 100 110 pF1KSD LALNFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRSVVYIHGGGWAL :... :: . :. .: ::.: :... :::. : . : :.:.. ::::::: . XP_005 ---NLVVGSFDEVPPTSDENVTVTETKFNNILVRVYV-PKRKSEALRRGLFYIHGGGWCV 50 60 70 80 90 100 120 130 140 150 160 170 pF1KSD ASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYM .:: . :: : :..:.::.:: .:::.:: .:: :..:: : ..::. .:: :: XP_005 GSAALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYG 110 120 130 140 150 160 180 190 200 210 220 230 pF1KSD VDPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVN :.: :: :::::::::::::. ::. .: ..: :::.:.::::.:: :: . ::::.: : XP_005 VNPERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSN 170 180 190 200 210 220 240 250 260 270 280 290 pF1KSD TPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKN .: . .::..: .:: . .. .::. .:. . :.. . .::.:::: : :. XP_005 FLFLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPV---ESSHLFKFVNWSSLLPERFIKG 230 240 250 260 270 300 310 320 330 340 350 pF1KSD YKPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAK . . :....... : .::.:.:::.::. :. :: ::..::..:.:::::.::. XP_005 HVYNNPNYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVT 280 290 300 310 320 330 360 370 380 390 400 pF1KSD RLESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKWLDQNL ::...::.:: .: :::::: . : ..... : :.::.:: .:: XP_005 RLRNTGVQVTHNHVEDGFHGAFSFL----GLKISHRLINQYIEWLKENL 340 350 360 370 380 >>XP_005258997 (OMIM: 151750,615980) PREDICTED: hormone- (775 aa) initn: 331 init1: 146 opt: 165 Z-score: 206.2 bits: 48.0 E(85289): 9.5e-05 Smith-Waterman score: 226; 31.1% identity (62.1% similar) in 161 aa overlap (93-250:328-481) 70 80 90 100 110 120 pF1KSD NFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEE-PLKRS-VVYIHGGGWALA : .: :.:.. : .:: .:..::::.. XP_005 GPVLVRLISYDLREGQDSEELSSLIKSNGQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQ 300 310 320 330 340 350 130 140 150 160 170 180 pF1KSD SAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMV .. : .. . :.::.: :.::.: :.:.. ::. ... : . .: .: . XP_005 TS--RSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCAL---LG 360 370 380 390 400 410 190 200 210 220 230 pF1KSD DPG-RICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVN . : :::..:::::::: ... . . ... ..: ::. . .:: .. XP_005 STGERICLAGDSAGGNLCFTVALR-AAAYGVRVPDGIMA-AYPATMLQPAASPSRLLSLM 420 430 440 450 460 470 240 250 260 270 280 290 pF1KSD TPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKN :.:: :. : XP_005 DPLLPLSVLSKCVSAYAGAKTEDHSNSDQKALGMMGLVRRDTALLLRDFRLGASSWLNSF 480 490 500 510 520 530 >-- initn: 206 init1: 146 opt: 165 Z-score: 206.2 bits: 48.0 E(85289): 9.5e-05 Smith-Waterman score: 165; 30.1% identity (65.6% similar) in 93 aa overlap (294-385:638-730) 270 280 290 300 310 320 pF1KSD QAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARI-VQELPQLLDA :.: ....: .. : ... . : . . XP_005 VNFLLPPEDAGEEAEAKNELSPMDRGLGVRAAFPEGFHPRRSSQGATQMPLYSSPIVKNP 610 620 630 640 650 660 330 340 350 360 370 380 pF1KSD RSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMI .::.: ...:. :: ..:..: : . ::..: :.::.. : ::: :: :: . XP_005 FMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLPHGFLT 670 680 690 700 710 720 390 400 pF1KSD FTSWPTNFSVGIRTRNSYIKWLDQNL ... XP_005 LAALCRETRQAAELCVERIRLVLTPPAGAGPSGETGAAGVDGGCGGRH 730 740 750 760 770 >>XP_006723281 (OMIM: 151750,615980) PREDICTED: hormone- (775 aa) initn: 331 init1: 146 opt: 165 Z-score: 206.2 bits: 48.0 E(85289): 9.5e-05 Smith-Waterman score: 226; 31.1% identity (62.1% similar) in 161 aa overlap (93-250:328-481) 70 80 90 100 110 120 pF1KSD NFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEE-PLKRS-VVYIHGGGWALA : .: :.:.. : .:: .:..::::.. XP_006 GPVLVRLISYDLREGQDSEELSSLIKSNGQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQ 300 310 320 330 340 350 130 140 150 160 170 180 pF1KSD SAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMV .. : .. . :.::.: :.::.: :.:.. ::. ... : . .: .: . XP_006 TS--RSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCAL---LG 360 370 380 390 400 410 190 200 210 220 230 pF1KSD DPG-RICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVN . : :::..:::::::: ... . . ... ..: ::. . .:: .. XP_006 STGERICLAGDSAGGNLCFTVALR-AAAYGVRVPDGIMA-AYPATMLQPAASPSRLLSLM 420 430 440 450 460 470 240 250 260 270 280 290 pF1KSD TPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKN :.:: :. : XP_006 DPLLPLSVLSKCVSAYAGAKTEDHSNSDQKALGMMGLVRRDTALLLRDFRLGASSWLNSF 480 490 500 510 520 530 >-- initn: 206 init1: 146 opt: 165 Z-score: 206.2 bits: 48.0 E(85289): 9.5e-05 Smith-Waterman score: 165; 30.1% identity (65.6% similar) in 93 aa overlap (294-385:638-730) 270 280 290 300 310 320 pF1KSD QAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARI-VQELPQLLDA :.: ....: .. : ... . : . . XP_006 VNFLLPPEDAGEEAEAKNELSPMDRGLGVRAAFPEGFHPRRSSQGATQMPLYSSPIVKNP 610 620 630 640 650 660 330 340 350 360 370 380 pF1KSD RSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMI .::.: ...:. :: ..:..: : . ::..: :.::.. : ::: :: :: . XP_006 FMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLPHGFLT 670 680 690 700 710 720 390 400 pF1KSD FTSWPTNFSVGIRTRNSYIKWLDQNL ... XP_006 LAALCRETRQAAELCVERIRLVLTPPAGAGPSGETGAAGVDGGCGGRH 730 740 750 760 770 >>XP_016882299 (OMIM: 151750,615980) PREDICTED: hormone- (775 aa) initn: 331 init1: 146 opt: 165 Z-score: 206.2 bits: 48.0 E(85289): 9.5e-05 Smith-Waterman score: 226; 31.1% identity (62.1% similar) in 161 aa overlap (93-250:328-481) 70 80 90 100 110 120 pF1KSD NFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEE-PLKRS-VVYIHGGGWALA : .: :.:.. : .:: .:..::::.. XP_016 GPVLVRLISYDLREGQDSEELSSLIKSNGQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQ 300 310 320 330 340 350 130 140 150 160 170 180 pF1KSD SAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMV .. : .. . :.::.: :.::.: :.:.. ::. ... : . .: .: . XP_016 TS--RSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCAL---LG 360 370 380 390 400 410 190 200 210 220 230 pF1KSD DPG-RICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVN . : :::..:::::::: ... . . ... ..: ::. . .:: .. XP_016 STGERICLAGDSAGGNLCFTVALR-AAAYGVRVPDGIMA-AYPATMLQPAASPSRLLSLM 420 430 440 450 460 470 240 250 260 270 280 290 pF1KSD TPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKN :.:: :. : XP_016 DPLLPLSVLSKCVSAYAGAKTEDHSNSDQKALGMMGLVRRDTALLLRDFRLGASSWLNSF 480 490 500 510 520 530 >-- initn: 206 init1: 146 opt: 165 Z-score: 206.2 bits: 48.0 E(85289): 9.5e-05 Smith-Waterman score: 165; 30.1% identity (65.6% similar) in 93 aa overlap (294-385:638-730) 270 280 290 300 310 320 pF1KSD QAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARI-VQELPQLLDA :.: ....: .. : ... . : . . XP_016 VNFLLPPEDAGEEAEAKNELSPMDRGLGVRAAFPEGFHPRRSSQGATQMPLYSSPIVKNP 610 620 630 640 650 660 330 340 350 360 370 380 pF1KSD RSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMI .::.: ...:. :: ..:..: : . ::..: :.::.. : ::: :: :: . XP_016 FMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLPHGFLT 670 680 690 700 710 720 390 400 pF1KSD FTSWPTNFSVGIRTRNSYIKWLDQNL ... XP_016 LAALCRETRQAAELCVERIRLVLTPPAGAGPSGETGAAGVDGGCGGRH 730 740 750 760 770 >>XP_005258995 (OMIM: 151750,615980) PREDICTED: hormone- (821 aa) initn: 307 init1: 146 opt: 165 Z-score: 205.9 bits: 48.0 E(85289): 0.0001 Smith-Waterman score: 226; 31.1% identity (62.1% similar) in 161 aa overlap (93-250:374-527) 70 80 90 100 110 120 pF1KSD NFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEE-PLKRS-VVYIHGGGWALA : .: :.:.. : .:: .:..::::.. XP_005 GPVLVRLISYDLREGQDSEELSSLIKSNGQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQ 350 360 370 380 390 400 130 140 150 160 170 180 pF1KSD SAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMV .. : .. . :.::.: :.::.: :.:.. ::. ... : . .: .: . XP_005 TS--RSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCAL---LG 410 420 430 440 450 190 200 210 220 230 pF1KSD DPG-RICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVN . : :::..:::::::: ... . . ... ..: ::. . .:: .. XP_005 STGERICLAGDSAGGNLCFTVALR-AAAYGVRVPDGIMA-AYPATMLQPAASPSRLLSLM 460 470 480 490 500 510 240 250 260 270 280 290 pF1KSD TPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKN :.:: :. : XP_005 DPLLPLSVLSKCVSAYAGAKTEDHSNSDQKALGMMGLVRRDTALLLRDFRLGASSWLNSF 520 530 540 550 560 570 >-- initn: 206 init1: 146 opt: 165 Z-score: 205.9 bits: 48.0 E(85289): 0.0001 Smith-Waterman score: 165; 30.1% identity (65.6% similar) in 93 aa overlap (294-385:684-776) 270 280 290 300 310 320 pF1KSD QAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARI-VQELPQLLDA :.: ....: .. : ... . : . . XP_005 VNFLLPPEDAGEEAEAKNELSPMDRGLGVRAAFPEGFHPRRSSQGATQMPLYSSPIVKNP 660 670 680 690 700 710 330 340 350 360 370 380 pF1KSD RSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFEDGFHGCMI .::.: ...:. :: ..:..: : . ::..: :.::.. : ::: :: :: . XP_005 FMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLPHGFLT 720 730 740 750 760 770 390 400 pF1KSD FTSWPTNFSVGIRTRNSYIKWLDQNL ... XP_005 LAALCRETRQAAELCVERIRLVLTPPAGAGPSGETGAAGVDGGCGGRH 780 790 800 810 820 408 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 05:59:39 2016 done: Thu Nov 3 05:59:40 2016 Total Scan time: 8.170 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]