FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1387, 849 aa 1>>>pF1KSDA1387 849 - 849 aa - 849 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3508+/-0.000419; mu= 10.9620+/- 0.026 mean_var=105.6732+/-21.113, 0's: 0 Z-trim(114.0): 27 B-trim: 267 in 2/52 Lambda= 0.124765 statistics sampled from 23610 (23631) to 23610 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.277), width: 16 Scan time: 12.990 The best scores are: opt bits E(85289) NP_001116436 (OMIM: 610352) serine/threonine-prote ( 849) 5530 1006.6 0 XP_005264499 (OMIM: 610352) PREDICTED: serine/thre ( 842) 5463 994.6 0 XP_005264504 (OMIM: 610352) PREDICTED: serine/thre ( 641) 3544 649.1 1.8e-185 XP_016860026 (OMIM: 610352) PREDICTED: serine/thre ( 544) 3542 648.7 2e-185 XP_016860027 (OMIM: 610352) PREDICTED: serine/thre ( 544) 3542 648.7 2e-185 XP_005264502 (OMIM: 610352) PREDICTED: serine/thre ( 789) 3503 641.8 3.7e-183 XP_005264501 (OMIM: 610352) PREDICTED: serine/thre ( 796) 3503 641.8 3.7e-183 XP_016860021 (OMIM: 610352) PREDICTED: serine/thre ( 634) 3478 637.2 6.8e-182 XP_005264503 (OMIM: 610352) PREDICTED: serine/thre ( 757) 3183 584.2 7.7e-166 NP_065196 (OMIM: 610352) serine/threonine-protein ( 764) 3183 584.2 7.8e-166 XP_016860020 (OMIM: 610352) PREDICTED: serine/thre ( 810) 3183 584.2 8.2e-166 NP_001269779 (OMIM: 610352) serine/threonine-prote ( 817) 3183 584.2 8.3e-166 NP_001271209 (OMIM: 610351) serine/threonine-prote ( 820) 2806 516.3 2.2e-145 XP_005267899 (OMIM: 610351) PREDICTED: serine/thre ( 833) 2350 434.2 1.2e-120 XP_016860028 (OMIM: 610352) PREDICTED: serine/thre ( 512) 2142 396.7 1.4e-109 XP_016860022 (OMIM: 610352) PREDICTED: serine/thre ( 609) 2142 396.8 1.6e-109 XP_016860024 (OMIM: 610352) PREDICTED: serine/thre ( 556) 1685 314.5 8.6e-85 XP_016860025 (OMIM: 610352) PREDICTED: serine/thre ( 549) 1198 226.8 2.1e-58 XP_016860023 (OMIM: 610352) PREDICTED: serine/thre ( 602) 1198 226.8 2.3e-58 XP_016860029 (OMIM: 610352) PREDICTED: serine/thre ( 505) 1196 226.5 2.5e-58 NP_001271210 (OMIM: 610351) serine/threonine-prote ( 594) 1153 218.7 6.1e-56 >>NP_001116436 (OMIM: 610352) serine/threonine-protein p (849 aa) initn: 5530 init1: 5530 opt: 5530 Z-score: 5380.6 bits: 1006.6 E(85289): 0 Smith-Waterman score: 5530; 100.0% identity (100.0% similar) in 849 aa overlap (1-849:1-849) 10 20 30 40 50 60 pF1KSD MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NTSEDKCEKDFFLKHYRYSWSFVCTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTSEDKCEKDFFLKHYRYSWSFVCTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KSD SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 790 800 810 820 830 840 pF1KSD PRKRPRLGS ::::::::: NP_001 PRKRPRLGS >>XP_005264499 (OMIM: 610352) PREDICTED: serine/threonin (842 aa) initn: 4538 init1: 4504 opt: 5463 Z-score: 5315.5 bits: 994.6 E(85289): 0 Smith-Waterman score: 5463; 99.1% identity (99.2% similar) in 849 aa overlap (1-849:1-842) 10 20 30 40 50 60 pF1KSD MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NTSEDKCEKDFFLKHYRYSWSFVCTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_005 NTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED :::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_005 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNS-------NRFRRDAKALEEDEEMWFNED 670 680 690 700 710 730 740 750 760 770 780 pF1KSD EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 720 730 740 750 760 770 790 800 810 820 830 840 pF1KSD SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 780 790 800 810 820 830 pF1KSD PRKRPRLGS ::::::::: XP_005 PRKRPRLGS 840 >>XP_005264504 (OMIM: 610352) PREDICTED: serine/threonin (641 aa) initn: 3544 init1: 3544 opt: 3544 Z-score: 3450.7 bits: 649.1 E(85289): 1.8e-185 Smith-Waterman score: 3768; 75.4% identity (75.5% similar) in 849 aa overlap (1-849:1-641) 10 20 30 40 50 60 pF1KSD MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE ::::::::::::::::::::::::::::::::::::::: XP_005 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQ--------------------- 70 80 90 130 140 150 160 170 180 pF1KSD RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ XP_005 ------------------------------------------------------------ 190 200 210 220 230 240 pF1KSD ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE XP_005 ------------------------------------------------------------ 250 260 270 280 290 300 pF1KSD FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV XP_005 ------------------------------------------------------------ 310 320 330 340 350 360 pF1KSD EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 -------EDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 100 110 120 130 140 150 370 380 390 400 410 420 pF1KSD KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 160 170 180 190 200 210 430 440 450 460 470 480 pF1KSD EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 220 230 240 250 260 270 490 500 510 520 530 540 pF1KSD NTSEDKCEKDFFLKHYRYSWSFVCTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_005 NTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT 280 290 300 310 320 330 550 560 570 580 590 600 pF1KSD AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL 340 350 360 370 380 390 610 620 630 640 650 660 pF1KSD KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 400 410 420 430 440 450 670 680 690 700 710 720 pF1KSD KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED 460 470 480 490 500 510 730 740 750 760 770 780 pF1KSD EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 520 530 540 550 560 570 790 800 810 820 830 840 pF1KSD SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 580 590 600 610 620 630 pF1KSD PRKRPRLGS ::::::::: XP_005 PRKRPRLGS 640 >>XP_016860026 (OMIM: 610352) PREDICTED: serine/threonin (544 aa) initn: 3542 init1: 3542 opt: 3542 Z-score: 3449.9 bits: 648.7 E(85289): 2e-185 Smith-Waterman score: 3542; 99.4% identity (100.0% similar) in 544 aa overlap (306-849:1-544) 280 290 300 310 320 330 pF1KSD ILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVN ..:::::::::::::::::::::::::::: XP_016 MEEDEKFLSEVFAQLTDEATDDDKRRELVN 10 20 30 340 350 360 370 380 390 pF1KSD FFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSP 40 50 60 70 80 90 400 410 420 430 440 450 pF1KSD SMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTN 100 110 120 130 140 150 460 470 480 490 500 510 pF1KSD KTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDFFLKHYRYSWSFVCTPSHSHSHSTP :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: XP_016 KTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTP 160 170 180 190 200 210 520 530 540 550 560 570 pF1KSD SSSISQDNIVGSNKNNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSISQDNIVGSNKNNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRV 220 230 240 250 260 270 580 590 600 610 620 630 pF1KSD LVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSA 280 290 300 310 320 330 640 650 660 670 680 690 pF1KSD VIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPS 340 350 360 370 380 390 700 710 720 730 740 750 pF1KSD ILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAK 400 410 420 430 440 450 760 770 780 790 800 810 pF1KSD ESEDKENLPKRTSPGGFKFTFSHSASAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESEDKENLPKRTSPGGFKFTFSHSASAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVT 460 470 480 490 500 510 820 830 840 pF1KSD ATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS :::::::::::::::::::::::::::::::::: XP_016 ATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS 520 530 540 >>XP_016860027 (OMIM: 610352) PREDICTED: serine/threonin (544 aa) initn: 3542 init1: 3542 opt: 3542 Z-score: 3449.9 bits: 648.7 E(85289): 2e-185 Smith-Waterman score: 3542; 99.4% identity (100.0% similar) in 544 aa overlap (306-849:1-544) 280 290 300 310 320 330 pF1KSD ILPTPSVFEENFLSTLTSFIFFNKVEIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVN ..:::::::::::::::::::::::::::: XP_016 MEEDEKFLSEVFAQLTDEATDDDKRRELVN 10 20 30 340 350 360 370 380 390 pF1KSD FFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFKEFCAFSQTLQPQNRDAFFKTLAKLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSP 40 50 60 70 80 90 400 410 420 430 440 450 pF1KSD SMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMVREFVMQEAQQSDDDILLINVVIEQMICDTDPELGGAVQLMGLLRTLIDPENMLATTN 100 110 120 130 140 150 460 470 480 490 500 510 pF1KSD KTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDFFLKHYRYSWSFVCTPSHSHSHSTP :::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::: XP_016 KTEKSEFLNFFYNHCMHVLTAPLLTNTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTP 160 170 180 190 200 210 520 530 540 550 560 570 pF1KSD SSSISQDNIVGSNKNNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSSISQDNIVGSNKNNTICPDNYQTAQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRV 220 230 240 250 260 270 580 590 600 610 620 630 pF1KSD LVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVLMNSKHTFLALCALRFMRRIIGLKDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSA 280 290 300 310 320 330 640 650 660 670 680 690 pF1KSD VIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIELFEFIRVEDIKSLTAHIVENFYKALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPS 340 350 360 370 380 390 700 710 720 730 740 750 pF1KSD ILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILRSNRFRRDAKALEEDEEMWFNEDEEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAK 400 410 420 430 440 450 760 770 780 790 800 810 pF1KSD ESEDKENLPKRTSPGGFKFTFSHSASAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESEDKENLPKRTSPGGFKFTFSHSASAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVT 460 470 480 490 500 510 820 830 840 pF1KSD ATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS :::::::::::::::::::::::::::::::::: XP_016 ATKGSLVGLVDYPDDEEEDEEEESSPRKRPRLGS 520 530 540 >>XP_005264502 (OMIM: 610352) PREDICTED: serine/threonin (789 aa) initn: 4481 init1: 3503 opt: 3503 Z-score: 3409.3 bits: 641.8 E(85289): 3.7e-183 Smith-Waterman score: 4994; 92.7% identity (92.8% similar) in 849 aa overlap (1-849:1-789) 10 20 30 40 50 60 pF1KSD MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NTSEDKCEKDFFLKHYRYSWSFVCTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT ::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_005 NTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPG---- 490 500 510 520 530 550 560 570 580 590 600 pF1KSD AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL ::::::::::: XP_005 -------------------------------------------------ALRFMRRIIGL 540 610 620 630 640 650 660 pF1KSD KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 550 560 570 580 590 600 670 680 690 700 710 720 pF1KSD KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED :::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_005 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNS-------NRFRRDAKALEEDEEMWFNED 610 620 630 640 650 660 730 740 750 760 770 780 pF1KSD EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 670 680 690 700 710 720 790 800 810 820 830 840 pF1KSD SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 730 740 750 760 770 780 pF1KSD PRKRPRLGS ::::::::: XP_005 PRKRPRLGS >>XP_005264501 (OMIM: 610352) PREDICTED: serine/threonin (796 aa) initn: 5163 init1: 3503 opt: 3503 Z-score: 3409.3 bits: 641.8 E(85289): 3.7e-183 Smith-Waterman score: 5060; 93.5% identity (93.6% similar) in 849 aa overlap (1-849:1-796) 10 20 30 40 50 60 pF1KSD MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NTSEDKCEKDFFLKHYRYSWSFVCTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT ::::::::::::::::::::::.:::::::::::::::::::::::::::::::: XP_005 NTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPG---- 490 500 510 520 530 550 560 570 580 590 600 pF1KSD AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL ::::::::::: XP_005 -------------------------------------------------ALRFMRRIIGL 540 610 620 630 640 650 660 pF1KSD KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 550 560 570 580 590 600 670 680 690 700 710 720 pF1KSD KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED 610 620 630 640 650 660 730 740 750 760 770 780 pF1KSD EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 670 680 690 700 710 720 790 800 810 820 830 840 pF1KSD SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 730 740 750 760 770 780 pF1KSD PRKRPRLGS ::::::::: XP_005 PRKRPRLGS 790 >>XP_016860021 (OMIM: 610352) PREDICTED: serine/threonin (634 aa) initn: 2553 init1: 2519 opt: 3478 Z-score: 3386.6 bits: 637.2 E(85289): 6.8e-182 Smith-Waterman score: 3702; 74.6% identity (74.7% similar) in 849 aa overlap (1-849:1-634) 10 20 30 40 50 60 pF1KSD MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE ::::::::::::::::::::::::::::::::::::::: XP_016 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQ--------------------- 70 80 90 130 140 150 160 170 180 pF1KSD RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ XP_016 ------------------------------------------------------------ 190 200 210 220 230 240 pF1KSD ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE XP_016 ------------------------------------------------------------ 250 260 270 280 290 300 pF1KSD FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV XP_016 ------------------------------------------------------------ 310 320 330 340 350 360 pF1KSD EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -------EDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 100 110 120 130 140 150 370 380 390 400 410 420 pF1KSD KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 160 170 180 190 200 210 430 440 450 460 470 480 pF1KSD EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 220 230 240 250 260 270 490 500 510 520 530 540 pF1KSD NTSEDKCEKDFFLKHYRYSWSFVCTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_016 NTSEDKCEKDFFLKHYRYSWSFICTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT 280 290 300 310 320 330 550 560 570 580 590 600 pF1KSD AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL 340 350 360 370 380 390 610 620 630 640 650 660 pF1KSD KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 400 410 420 430 440 450 670 680 690 700 710 720 pF1KSD KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED :::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_016 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNS-------NRFRRDAKALEEDEEMWFNED 460 470 480 490 500 730 740 750 760 770 780 pF1KSD EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 510 520 530 540 550 560 790 800 810 820 830 840 pF1KSD SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 570 580 590 600 610 620 pF1KSD PRKRPRLGS ::::::::: XP_016 PRKRPRLGS 630 >>XP_005264503 (OMIM: 610352) PREDICTED: serine/threonin (757 aa) initn: 4161 init1: 3183 opt: 3183 Z-score: 3098.3 bits: 584.2 E(85289): 7.7e-166 Smith-Waterman score: 4690; 89.0% identity (89.0% similar) in 849 aa overlap (1-849:1-757) 10 20 30 40 50 60 pF1KSD MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NTSEDKCEKDFFLKHYRYSWSFVCTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT :::::::::: ::::::::::::: XP_005 NTSEDKCEKD--------------------------------NIVGSNKNNTICPG---- 490 500 550 560 570 580 590 600 pF1KSD AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL ::::::::::: XP_005 -------------------------------------------------ALRFMRRIIGL 510 610 620 630 640 650 660 pF1KSD KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 520 530 540 550 560 570 670 680 690 700 710 720 pF1KSD KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED :::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_005 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNS-------NRFRRDAKALEEDEEMWFNED 580 590 600 610 620 730 740 750 760 770 780 pF1KSD EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 630 640 650 660 670 680 790 800 810 820 830 840 pF1KSD SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 690 700 710 720 730 740 pF1KSD PRKRPRLGS ::::::::: XP_005 PRKRPRLGS 750 >>NP_065196 (OMIM: 610352) serine/threonine-protein phos (764 aa) initn: 4843 init1: 3183 opt: 3183 Z-score: 3098.3 bits: 584.2 E(85289): 7.8e-166 Smith-Waterman score: 4756; 89.9% identity (89.9% similar) in 849 aa overlap (1-849:1-764) 10 20 30 40 50 60 pF1KSD MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MSDTRRRVKVYTLNEDRQWDDRGTGHVSSTYVEELKGMSLLVRAESDGSLLLESKINPNT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 AYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVEVTQDLIDESEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RFEEMPETSHLIDLPTCELNKLEEIADLVTSVLSSPIRREKLALALENEGYIKKLLQLFQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ACENLENTEGLHHLYEIIRGILFLNKATLFEVMFSDECIMDVVGCLEYDPALAQPKRHRE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 FLTKTAKFKEVIPITDSELRQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIFFNKV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EIVSMLQEDEKFLSEVFAQLTDEATDDDKRRELVNFFKEFCAFSQTLQPQNRDAFFKTLA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 KLGILPALEIVMGMDDLQVRSAATDIFSYLVEFSPSMVREFVMQEAQQSDDDILLINVVI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EQMICDTDPELGGAVQLMGLLRTLIDPENMLATTNKTEKSEFLNFFYNHCMHVLTAPLLT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD NTSEDKCEKDFFLKHYRYSWSFVCTPSHSHSHSTPSSSISQDNIVGSNKNNTICPDNYQT :::::::::: ::::::::::::: NP_065 NTSEDKCEKD--------------------------------NIVGSNKNNTICPG---- 490 500 550 560 570 580 590 600 pF1KSD AQLLALILELLTFCVEHHTYHIKNYIMNKDLLRRVLVLMNSKHTFLALCALRFMRRIIGL ::::::::::: NP_065 -------------------------------------------------ALRFMRRIIGL 510 610 620 630 640 650 660 pF1KSD KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 KDEFYNRYITKGNLFEPVINALLDNGTRYNLLNSAVIELFEFIRVEDIKSLTAHIVENFY 520 530 540 550 560 570 670 680 690 700 710 720 pF1KSD KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 KALESIEYVQTFKGLKTKYEQEKDRQNQKLNSVPSILRSNRFRRDAKALEEDEEMWFNED 580 590 600 610 620 630 730 740 750 760 770 780 pF1KSD EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EEEEGKAVVAPVEKPKPEDDFPDNYEKFMETKKAKESEDKENLPKRTSPGGFKFTFSHSA 640 650 660 670 680 690 790 800 810 820 830 840 pF1KSD SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SAANGTNSKSVVAQIPPATSNGSSSKTTNLPTSVTATKGSLVGLVDYPDDEEEDEEEESS 700 710 720 730 740 750 pF1KSD PRKRPRLGS ::::::::: NP_065 PRKRPRLGS 760 849 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:04:18 2016 done: Thu Nov 3 06:04:20 2016 Total Scan time: 12.990 Total Display time: 0.270 Function used was FASTA [36.3.4 Apr, 2011]