Result of FASTA (omim) for
pF1KSDA1394
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1394, 966 aa
1>>>pF1KSDA1394 966 - 966 aa - 966 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9367+/-0.000312; mu= 19.0858+/- 0.019
mean_var=92.3188+/-18.536, 0's: 0 Z-trim(118.0): 16 B-trim: 245 in 1/54
Lambda= 0.133484
statistics sampled from 30575 (30590) to 30575 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.359), width: 16
Scan time: 15.000
The best scores are: opt bits E(85289)
XP_016873543 (OMIM: 613368) PREDICTED: carnosine s ( 966) 6607 1283.0 0
NP_001159694 (OMIM: 613368) carnosine synthase 1 i ( 950) 6480 1258.5 0
XP_011543491 (OMIM: 613368) PREDICTED: carnosine s ( 950) 6480 1258.5 0
XP_016873544 (OMIM: 613368) PREDICTED: carnosine s ( 936) 5607 1090.4 0
NP_065862 (OMIM: 613368) carnosine synthase 1 isof ( 827) 5584 1085.9 0
XP_011543493 (OMIM: 613368) PREDICTED: carnosine s ( 577) 3787 739.7 9.8e-213
>>XP_016873543 (OMIM: 613368) PREDICTED: carnosine synth (966 aa)
initn: 6607 init1: 6607 opt: 6607 Z-score: 6872.0 bits: 1283.0 E(85289): 0
Smith-Waterman score: 6607; 100.0% identity (100.0% similar) in 966 aa overlap (1-966:1-966)
10 20 30 40 50 60
pF1KSD MCPLAHPAQDLPLLPSQLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCPLAHPAQDLPLLPSQLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
910 920 930 940 950 960
pF1KSD FLSHFK
::::::
XP_016 FLSHFK
>>NP_001159694 (OMIM: 613368) carnosine synthase 1 isofo (950 aa)
initn: 6480 init1: 6480 opt: 6480 Z-score: 6740.0 bits: 1258.5 E(85289): 0
Smith-Waterman score: 6480; 100.0% identity (100.0% similar) in 949 aa overlap (18-966:2-950)
10 20 30 40 50 60
pF1KSD MCPLAHPAQDLPLLPSQLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
:::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
10 20 30 40
70 80 90 100 110 120
pF1KSD DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
350 360 370 380 390 400
430 440 450 460 470 480
pF1KSD EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
650 660 670 680 690 700
730 740 750 760 770 780
pF1KSD LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
710 720 730 740 750 760
790 800 810 820 830 840
pF1KSD ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
770 780 790 800 810 820
850 860 870 880 890 900
pF1KSD WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
830 840 850 860 870 880
910 920 930 940 950 960
pF1KSD LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
890 900 910 920 930 940
pF1KSD FLSHFK
::::::
NP_001 FLSHFK
950
>>XP_011543491 (OMIM: 613368) PREDICTED: carnosine synth (950 aa)
initn: 6480 init1: 6480 opt: 6480 Z-score: 6740.0 bits: 1258.5 E(85289): 0
Smith-Waterman score: 6480; 100.0% identity (100.0% similar) in 949 aa overlap (18-966:2-950)
10 20 30 40 50 60
pF1KSD MCPLAHPAQDLPLLPSQLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
:::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
10 20 30 40
70 80 90 100 110 120
pF1KSD DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KSD SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
110 120 130 140 150 160
190 200 210 220 230 240
pF1KSD DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
170 180 190 200 210 220
250 260 270 280 290 300
pF1KSD GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
230 240 250 260 270 280
310 320 330 340 350 360
pF1KSD VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KSD PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
350 360 370 380 390 400
430 440 450 460 470 480
pF1KSD EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
410 420 430 440 450 460
490 500 510 520 530 540
pF1KSD ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
470 480 490 500 510 520
550 560 570 580 590 600
pF1KSD GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
530 540 550 560 570 580
610 620 630 640 650 660
pF1KSD ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
590 600 610 620 630 640
670 680 690 700 710 720
pF1KSD PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
650 660 670 680 690 700
730 740 750 760 770 780
pF1KSD LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
710 720 730 740 750 760
790 800 810 820 830 840
pF1KSD ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
770 780 790 800 810 820
850 860 870 880 890 900
pF1KSD WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
830 840 850 860 870 880
910 920 930 940 950 960
pF1KSD LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
890 900 910 920 930 940
pF1KSD FLSHFK
::::::
XP_011 FLSHFK
950
>>XP_016873544 (OMIM: 613368) PREDICTED: carnosine synth (936 aa)
initn: 5607 init1: 5607 opt: 5607 Z-score: 5831.5 bits: 1090.4 E(85289): 0
Smith-Waterman score: 6329; 96.9% identity (96.9% similar) in 966 aa overlap (1-966:1-936)
10 20 30 40 50 60
pF1KSD MCPLAHPAQDLPLLPSQLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCPLAHPAQDLPLLPSQLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTG------------
70 80 90 100
130 140 150 160 170 180
pF1KSD SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
::::::::::::::::::::::::::::::::::::::::::
XP_016 ------------------NMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
110 120 130 140 150
190 200 210 220 230 240
pF1KSD DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KSD VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KSD EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
400 410 420 430 440 450
490 500 510 520 530 540
pF1KSD ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
460 470 480 490 500 510
550 560 570 580 590 600
pF1KSD GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
520 530 540 550 560 570
610 620 630 640 650 660
pF1KSD ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPA
580 590 600 610 620 630
670 680 690 700 710 720
pF1KSD PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRD
640 650 660 670 680 690
730 740 750 760 770 780
pF1KSD LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETA
700 710 720 730 740 750
790 800 810 820 830 840
pF1KSD ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRD
760 770 780 790 800 810
850 860 870 880 890 900
pF1KSD WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQA
820 830 840 850 860 870
910 920 930 940 950 960
pF1KSD LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAH
880 890 900 910 920 930
pF1KSD FLSHFK
::::::
XP_016 FLSHFK
>>NP_065862 (OMIM: 613368) carnosine synthase 1 isoform (827 aa)
initn: 5584 init1: 5584 opt: 5584 Z-score: 5808.3 bits: 1085.9 E(85289): 0
Smith-Waterman score: 5584; 100.0% identity (100.0% similar) in 827 aa overlap (140-966:1-827)
110 120 130 140 150 160
pF1KSD PGAEVTLCVLGSPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAV
::::::::::::::::::::::::::::::
NP_065 MLLCLSPAWLMKVPAPGQPGEAALLVSKAV
10 20 30
170 180 190 200 210 220
pF1KSD SFHPGGLTFLDDFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SFHPGGLTFLDDFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDR
40 50 60 70 80 90
230 240 250 260 270 280
pF1KSD LLTRQLLAQQGGVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LLTRQLLAQQGGVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAF
100 110 120 130 140 150
290 300 310 320 330 340
pF1KSD LRSEALGDILQVAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LRSEALGDILQVAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAV
160 170 180 190 200 210
350 360 370 380 390 400
pF1KSD YPPAQLPCSDGPSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YPPAQLPCSDGPSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTL
220 230 240 250 260 270
410 420 430 440 450 460
pF1KSD EVALAQCGLGEEAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EVALAQCGLGEEAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFA
280 290 300 310 320 330
470 480 490 500 510 520
pF1KSD LTAAGGVLTPVALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LTAAGGVLTPVALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCL
340 350 360 370 380 390
530 540 550 560 570 580
pF1KSD MEGKQLLVVGAGGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MEGKQLLVVGAGGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDE
400 410 420 430 440 450
590 600 610 620 630 640
pF1KSD ENARLLAELVRARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ENARLLAELVRARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLH
460 470 480 490 500 510
650 660 670 680 690 700
pF1KSD LLHHHGPPWPAPSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LLHHHGPPWPAPSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQ
520 530 540 550 560 570
710 720 730 740 750 760
pF1KSD CHEHFSRITRDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CHEHFSRITRDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNG
580 590 600 610 620 630
770 780 790 800 810 820
pF1KSD PTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEI
640 650 660 670 680 690
830 840 850 860 870 880
pF1KSD NPRMGGFYLRDWILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NPRMGGFYLRDWILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQAL
700 710 720 730 740 750
890 900 910 920 930 940
pF1KSD SSTASRETLQALHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSTASRETLQALHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGL
760 770 780 790 800 810
950 960
pF1KSD GIDGPSYPVAHFLSHFK
:::::::::::::::::
NP_065 GIDGPSYPVAHFLSHFK
820
>>XP_011543493 (OMIM: 613368) PREDICTED: carnosine synth (577 aa)
initn: 3787 init1: 3787 opt: 3787 Z-score: 3940.2 bits: 739.7 E(85289): 9.8e-213
Smith-Waterman score: 3787; 100.0% identity (100.0% similar) in 558 aa overlap (1-558:1-558)
10 20 30 40 50 60
pF1KSD MCPLAHPAQDLPLLPSQLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MCPLAHPAQDLPLLPSQLSLDPSGPEWDCPLGSKDLEEEGPWGGGSGLPPTGCFPGSWRQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQVPRTGCPGAEVTLCVLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVR
::::::::::::::::::
XP_011 GGVSKKFVWEAARDYGLQAGVEWRNLGPLQPLPPGFK
550 560 570
966 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 06:07:15 2016 done: Thu Nov 3 06:07:18 2016
Total Scan time: 15.000 Total Display time: 0.210
Function used was FASTA [36.3.4 Apr, 2011]