FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1399, 410 aa 1>>>pF1KSDA1399 410 - 410 aa - 410 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6880+/-0.00082; mu= 5.1109+/- 0.050 mean_var=261.5199+/-52.392, 0's: 0 Z-trim(117.1): 12 B-trim: 0 in 0/53 Lambda= 0.079309 statistics sampled from 17804 (17816) to 17804 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.826), E-opt: 0.2 (0.547), width: 16 Scan time: 3.290 The best scores are: opt bits E(32554) CCDS33376.1 MARCH4 gene_id:57574|Hs108|chr2 ( 410) 3001 355.9 4.1e-98 CCDS31847.1 MARCH9 gene_id:92979|Hs108|chr12 ( 346) 1194 149.0 6.3e-36 CCDS47192.1 MARCH11 gene_id:441061|Hs108|chr5 ( 402) 975 124.0 2.4e-28 >>CCDS33376.1 MARCH4 gene_id:57574|Hs108|chr2 (410 aa) initn: 3001 init1: 3001 opt: 3001 Z-score: 1874.9 bits: 355.9 E(32554): 4.1e-98 Smith-Waterman score: 3001; 100.0% identity (100.0% similar) in 410 aa overlap (1-410:1-410) 10 20 30 40 50 60 pF1KSD MLMPLCGLLWWWWCCCSGWYCYGLCAPAPQMLRHQGLLKCRCRMLFNDLKVFLLRRPPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MLMPLCGLLWWWWCCCSGWYCYGLCAPAPQMLRHQGLLKCRCRMLFNDLKVFLLRRPPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD PLPMHGDPQPPGLAANNTLPALGAGGWAGWRGPREVVGREPPPVPPPPPLPPSSVEDDWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 PLPMHGDPQPPGLAANNTLPALGAGGWAGWRGPREVVGREPPPVPPPPPLPPSSVEDDWG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD GPATEPPASLLSSASSDDFCKEKTEDRYSLGSSLDSGMRTPLCRICFQGPEQGELLSPCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GPATEPPASLLSSASSDDFCKEKTEDRYSLGSSLDSGMRTPLCRICFQGPEQGELLSPCR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD CDGSVKCTHQPCLIKWISERGCWSCELCYYKYHVIAISTKNPLQWQAISLTVIEKVQVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 CDGSVKCTHQPCLIKWISERGCWSCELCYYKYHVIAISTKNPLQWQAISLTVIEKVQVAA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD AILGSLFLIASISWLIWSTFSPSARWQRQDLLFQICYGMYGFMDVVCIGLIIHEGPSVYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 AILGSLFLIASISWLIWSTFSPSARWQRQDLLFQICYGMYGFMDVVCIGLIIHEGPSVYR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD IFKRWQAVNQQWKVLNYDKTKDLEDQKAGGRTNPRTSSSTQANIPSSEEETAGTPAPEQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 IFKRWQAVNQQWKVLNYDKTKDLEDQKAGGRTNPRTSSSTQANIPSSEEETAGTPAPEQG 310 320 330 340 350 360 370 380 390 400 410 pF1KSD PAQAAGHPSGPLSHHHCAYTILHILSHLRPHEQRSPPGSSRELVMRVTTV :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 PAQAAGHPSGPLSHHHCAYTILHILSHLRPHEQRSPPGSSRELVMRVTTV 370 380 390 400 410 >>CCDS31847.1 MARCH9 gene_id:92979|Hs108|chr12 (346 aa) initn: 1393 init1: 1174 opt: 1194 Z-score: 758.5 bits: 149.0 E(32554): 6.3e-36 Smith-Waterman score: 1367; 58.3% identity (70.7% similar) in 386 aa overlap (37-410:1-346) 10 20 30 40 50 60 pF1KSD GLLWWWWCCCSGWYCYGLCAPAPQMLRHQGLLKCRCRMLFNDLKVFLLR---RPPQAPLP .:: : ::..:.::...: :: : : CCDS31 MLKSRLRMFLNELKLLVLTGGGRPRAEPQP 10 20 30 70 80 90 100 110 pF1KSD MHGDPQPPGLAA-NNTLPALGAGGWAGWRG--PRE--VVG-REPPPVPPPPPLPPSSVED : : : . : : . : :: ..: .:: : ::: :: CCDS31 RGGRGGGCGWAPFAGCSTRDGDGDEEEYYGSEPRARGLAGDKEPRAGPLPPPAPP----- 40 50 60 70 80 120 130 140 150 160 170 pF1KSD DWGGPATEPPASLLSSASSDDFCKEKTEDRYSLGSSLDSGMRTPLCRICFQGPEQGELLS ::..: : ::.::::::.::: ::::::::::::::: CCDS31 ------LPPPGAL---------------DALSLSSSLDSGLRTPQCRICFQGPEQGELLS 90 100 110 120 180 190 200 210 220 230 pF1KSD PCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKYHVIAISTKNPLQWQAISLTVIEKVQ ::::::::.::::::::.:::::: :::::::.::.:.:::::::::::::::::::::: CCDS31 PCRCDGSVRCTHQPCLIRWISERGSWSCELCYFKYQVLAISTKNPLQWQAISLTVIEKVQ 130 140 150 160 170 180 240 250 260 270 280 290 pF1KSD VAAAILGSLFLIASISWLIWSTFSPSARWQRQDLLFQICYGMYGFMDVVCIGLIIHEGPS .:: .::::::.:::::::::..::::.:::::::::::::::::::::::::::::: : CCDS31 IAAIVLGSLFLVASISWLIWSSLSPSAKWQRQDLLFQICYGMYGFMDVVCIGLIIHEGSS 190 200 210 220 230 240 300 310 320 330 340 350 pF1KSD VYRIFKRWQAVNQQWKVLNYDKTKDLEDQKAGG---RTNPRTSSSTQANIPSSEEETAGT :::::::::::::::::::::::::. . .:: ...::.: . :.: ..: CCDS31 VYRIFKRWQAVNQQWKVLNYDKTKDIGGDAGGGTAGKSGPRNSRTG----PTS----GAT 250 260 270 280 290 360 370 380 390 400 410 pF1KSD PAPEQGPAQAAGHPSGPLSHHHCAYTILHILSHLRPHEQRSPPGSSRELVMRVTTV : :: . : ..:.:::::.:..::: . :: :.::.::::::: CCDS31 SRP---PAAQRMRTLLP---QRCGYTILHLLGQLRPPDARSSSHSGREVVMRVTTV 300 310 320 330 340 >>CCDS47192.1 MARCH11 gene_id:441061|Hs108|chr5 (402 aa) initn: 1124 init1: 958 opt: 975 Z-score: 622.2 bits: 124.0 E(32554): 2.4e-28 Smith-Waterman score: 1122; 47.2% identity (66.8% similar) in 392 aa overlap (57-410:28-402) 30 40 50 60 70 80 pF1KSD PAPQMLRHQGLLKCRCRMLFNDLKVFLLRRPPQAPLPMHGDPQP-PGLAANNTLPALGAG :: : : :.: : : :: :: : :. CCDS47 MSFEGGHGGSRCRGAESGDAEPPPQPPPPPPPTPPPGEPAPVP--AAPRYLPPLPAS 10 20 30 40 50 90 100 110 120 130 pF1KSD GWAGWR--GPREVVGREPP------PVPPPP-PLPPSSVE-----DDWGGPATEPPASLL . : :: : .:. : .:::: :: :.. : :. :: : :. CCDS47 PETPERAAGPSEPLGEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAA 60 70 80 90 100 110 140 150 160 pF1KSD SSASSDDFCKEKTE-DRYSLGS-----------SLDSG-----------MRTPLCRICFQ ... ... : .: . :. : .:: . :.:.:::: CCDS47 KGGPGESEAGAGGERERRGAGDQPETRSVCSSRSSSSGGGDQRAGHQHQHHQPICKICFQ 120 130 140 150 160 170 170 180 190 200 210 220 pF1KSD GPEQGELLSPCRCDGSVKCTHQPCLIKWISERGCWSCELCYYKYHVIAISTKNPLQWQAI : ::::::.::::::::. ::: ::.::::::: :.:::: :.::::::. :.: :::.: CCDS47 GAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELCCYRYHVIAIKMKQPCQWQSI 180 190 200 210 220 230 230 240 250 260 270 280 pF1KSD SLTVIEKVQVAAAILGSLFLIASISWLIWSTFSPSARWQRQDLLFQICYGMYGFMDVVCI :.:..::::. :.::::::::::..::.::.::: : :::.:.:::::::::::::.::: CCDS47 SITLVEKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDILFQICYGMYGFMDLVCI 240 250 260 270 280 290 290 300 310 320 330 340 pF1KSD GLIIHEGPSVYRIFKRWQAVNQQWKVLNYDKTKDLEDQKAGGRTNPRTSSSTQANIPSSE :::.::: .:::.::::.::: .: ::::::. :.:... : ..:.: .: . CCDS47 GLIVHEGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRG-----ESSTSRTLWLPLTA 300 310 320 330 340 350 350 360 370 380 390 400 pF1KSD EETAGTPAPEQGPAQAAGHPSGPLSHHHCAYTILHILSHLRPHEQRSPPGSSRELVMRVT .. . : : ..: . .:.:..::.....::::. : .:: :.::::: CCDS47 LRNRNLVHPTQL--------TSP--RFQCGYVLLHLFNRMRPHEDLSEDNSSGEVVMRVT 360 370 380 390 400 410 pF1KSD TV .: CCDS47 SV 410 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:08:37 2016 done: Thu Nov 3 06:08:38 2016 Total Scan time: 3.290 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]