FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1437, 810 aa 1>>>pF1KSDA1437 810 - 810 aa - 810 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1089+/-0.000503; mu= 16.3851+/- 0.031 mean_var=102.7767+/-21.900, 0's: 0 Z-trim(110.4): 434 B-trim: 758 in 1/51 Lambda= 0.126511 statistics sampled from 18230 (18739) to 18230 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.57), E-opt: 0.2 (0.22), width: 16 Scan time: 12.370 The best scores are: opt bits E(85289) NP_001120716 (OMIM: 608360,613506) volume-regulate ( 810) 5363 990.7 0 XP_006717249 (OMIM: 608360,613506) PREDICTED: volu ( 810) 5363 990.7 0 NP_062540 (OMIM: 608360,613506) volume-regulated a ( 810) 5363 990.7 0 XP_005252152 (OMIM: 608360,613506) PREDICTED: volu ( 810) 5363 990.7 0 NP_001120717 (OMIM: 608360,613506) volume-regulate ( 810) 5363 990.7 0 XP_011517166 (OMIM: 608360,613506) PREDICTED: volu ( 810) 5363 990.7 0 XP_011517165 (OMIM: 608360,613506) PREDICTED: volu ( 810) 5363 990.7 0 XP_005252153 (OMIM: 608360,613506) PREDICTED: volu ( 810) 5363 990.7 0 XP_011517167 (OMIM: 608360,613506) PREDICTED: volu ( 810) 5363 990.7 0 XP_005270760 (OMIM: 612888) PREDICTED: volume-regu ( 803) 3188 593.7 1e-168 NP_056165 (OMIM: 612888) volume-regulated anion ch ( 803) 3188 593.7 1e-168 XP_011539447 (OMIM: 612888) PREDICTED: volume-regu ( 803) 3188 593.7 1e-168 NP_001127948 (OMIM: 612888) volume-regulated anion ( 803) 3188 593.7 1e-168 XP_011539445 (OMIM: 612888) PREDICTED: volume-regu ( 803) 3188 593.7 1e-168 XP_011539448 (OMIM: 612888) PREDICTED: volume-regu ( 803) 3188 593.7 1e-168 XP_005270758 (OMIM: 612888) PREDICTED: volume-regu ( 803) 3188 593.7 1e-168 XP_005270759 (OMIM: 612888) PREDICTED: volume-regu ( 803) 3188 593.7 1e-168 XP_016856373 (OMIM: 612888) PREDICTED: volume-regu ( 803) 3188 593.7 1e-168 XP_011539446 (OMIM: 612888) PREDICTED: volume-regu ( 803) 3188 593.7 1e-168 XP_016856374 (OMIM: 612888) PREDICTED: volume-regu ( 803) 3188 593.7 1e-168 XP_016856372 (OMIM: 612888) PREDICTED: volume-regu ( 803) 3188 593.7 1e-168 NP_115646 (OMIM: 612889) volume-regulated anion ch ( 803) 3184 593.0 1.7e-168 XP_016857992 (OMIM: 612889) PREDICTED: volume-regu ( 803) 3182 592.6 2.2e-168 XP_011540584 (OMIM: 612889) PREDICTED: volume-regu ( 803) 3182 592.6 2.2e-168 XP_006711023 (OMIM: 612889) PREDICTED: volume-regu ( 808) 3182 592.7 2.2e-168 XP_016856375 (OMIM: 612888) PREDICTED: volume-regu ( 731) 2898 540.8 8.2e-153 XP_011539450 (OMIM: 612888) PREDICTED: volume-regu ( 731) 2898 540.8 8.2e-153 XP_016857091 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2846 531.3 6.6e-150 NP_001127951 (OMIM: 612890) volume-regulated anion ( 858) 2846 531.3 6.6e-150 XP_011539991 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2846 531.3 6.6e-150 XP_016857089 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2846 531.3 6.6e-150 XP_016857090 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2846 531.3 6.6e-150 XP_016857088 (OMIM: 612890) PREDICTED: volume-regu ( 858) 2846 531.3 6.6e-150 NP_060573 (OMIM: 612890) volume-regulated anion ch ( 858) 2846 531.3 6.6e-150 NP_079337 (OMIM: 612891) volume-regulated anion ch ( 796) 2632 492.3 3.6e-138 NP_001255213 (OMIM: 612891) volume-regulated anion ( 796) 2632 492.3 3.6e-138 XP_011526621 (OMIM: 612891) PREDICTED: volume-regu ( 796) 2632 492.3 3.6e-138 XP_016857993 (OMIM: 612889) PREDICTED: volume-regu ( 773) 2587 484.0 1e-135 XP_011540585 (OMIM: 612889) PREDICTED: volume-regu ( 778) 2587 484.0 1e-135 NP_001255214 (OMIM: 612891) volume-regulated anion ( 667) 2429 455.2 4.5e-127 XP_016857384 (OMIM: 614453) PREDICTED: leucine-ric (1255) 403 85.6 1.5e-15 XP_016857383 (OMIM: 614453) PREDICTED: leucine-ric (1438) 403 85.6 1.7e-15 XP_016857382 (OMIM: 614453) PREDICTED: leucine-ric (1472) 403 85.6 1.7e-15 XP_016857381 (OMIM: 614453) PREDICTED: leucine-ric (1490) 403 85.6 1.7e-15 NP_001317564 (OMIM: 614453) leucine-rich repeat-co (1495) 403 85.6 1.7e-15 XP_016857379 (OMIM: 614453) PREDICTED: leucine-ric (1528) 403 85.6 1.7e-15 NP_065845 (OMIM: 614453) leucine-rich repeat-conta (1537) 403 85.6 1.8e-15 XP_016857378 (OMIM: 614453) PREDICTED: leucine-ric (1537) 403 85.6 1.8e-15 XP_016857377 (OMIM: 614453) PREDICTED: leucine-ric (1541) 403 85.6 1.8e-15 XP_016857376 (OMIM: 614453) PREDICTED: leucine-ric (1547) 403 85.7 1.8e-15 >>NP_001120716 (OMIM: 608360,613506) volume-regulated an (810 aa) initn: 5363 init1: 5363 opt: 5363 Z-score: 5295.4 bits: 990.7 E(85289): 0 Smith-Waterman score: 5363; 100.0% identity (100.0% similar) in 810 aa overlap (1-810:1-810) 10 20 30 40 50 60 pF1KSD MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK 730 740 750 760 770 780 790 800 810 pF1KSD RSGLVVEEDLFNTLPPEVKERLWRADKEQA :::::::::::::::::::::::::::::: NP_001 RSGLVVEEDLFNTLPPEVKERLWRADKEQA 790 800 810 >>XP_006717249 (OMIM: 608360,613506) PREDICTED: volume-r (810 aa) initn: 5363 init1: 5363 opt: 5363 Z-score: 5295.4 bits: 990.7 E(85289): 0 Smith-Waterman score: 5363; 100.0% identity (100.0% similar) in 810 aa overlap (1-810:1-810) 10 20 30 40 50 60 pF1KSD MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK 730 740 750 760 770 780 790 800 810 pF1KSD RSGLVVEEDLFNTLPPEVKERLWRADKEQA :::::::::::::::::::::::::::::: XP_006 RSGLVVEEDLFNTLPPEVKERLWRADKEQA 790 800 810 >>NP_062540 (OMIM: 608360,613506) volume-regulated anion (810 aa) initn: 5363 init1: 5363 opt: 5363 Z-score: 5295.4 bits: 990.7 E(85289): 0 Smith-Waterman score: 5363; 100.0% identity (100.0% similar) in 810 aa overlap (1-810:1-810) 10 20 30 40 50 60 pF1KSD MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK 730 740 750 760 770 780 790 800 810 pF1KSD RSGLVVEEDLFNTLPPEVKERLWRADKEQA :::::::::::::::::::::::::::::: NP_062 RSGLVVEEDLFNTLPPEVKERLWRADKEQA 790 800 810 >>XP_005252152 (OMIM: 608360,613506) PREDICTED: volume-r (810 aa) initn: 5363 init1: 5363 opt: 5363 Z-score: 5295.4 bits: 990.7 E(85289): 0 Smith-Waterman score: 5363; 100.0% identity (100.0% similar) in 810 aa overlap (1-810:1-810) 10 20 30 40 50 60 pF1KSD MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK 730 740 750 760 770 780 790 800 810 pF1KSD RSGLVVEEDLFNTLPPEVKERLWRADKEQA :::::::::::::::::::::::::::::: XP_005 RSGLVVEEDLFNTLPPEVKERLWRADKEQA 790 800 810 >>NP_001120717 (OMIM: 608360,613506) volume-regulated an (810 aa) initn: 5363 init1: 5363 opt: 5363 Z-score: 5295.4 bits: 990.7 E(85289): 0 Smith-Waterman score: 5363; 100.0% identity (100.0% similar) in 810 aa overlap (1-810:1-810) 10 20 30 40 50 60 pF1KSD MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK 730 740 750 760 770 780 790 800 810 pF1KSD RSGLVVEEDLFNTLPPEVKERLWRADKEQA :::::::::::::::::::::::::::::: NP_001 RSGLVVEEDLFNTLPPEVKERLWRADKEQA 790 800 810 >>XP_011517166 (OMIM: 608360,613506) PREDICTED: volume-r (810 aa) initn: 5363 init1: 5363 opt: 5363 Z-score: 5295.4 bits: 990.7 E(85289): 0 Smith-Waterman score: 5363; 100.0% identity (100.0% similar) in 810 aa overlap (1-810:1-810) 10 20 30 40 50 60 pF1KSD MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK 730 740 750 760 770 780 790 800 810 pF1KSD RSGLVVEEDLFNTLPPEVKERLWRADKEQA :::::::::::::::::::::::::::::: XP_011 RSGLVVEEDLFNTLPPEVKERLWRADKEQA 790 800 810 >>XP_011517165 (OMIM: 608360,613506) PREDICTED: volume-r (810 aa) initn: 5363 init1: 5363 opt: 5363 Z-score: 5295.4 bits: 990.7 E(85289): 0 Smith-Waterman score: 5363; 100.0% identity (100.0% similar) in 810 aa overlap (1-810:1-810) 10 20 30 40 50 60 pF1KSD MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK 730 740 750 760 770 780 790 800 810 pF1KSD RSGLVVEEDLFNTLPPEVKERLWRADKEQA :::::::::::::::::::::::::::::: XP_011 RSGLVVEEDLFNTLPPEVKERLWRADKEQA 790 800 810 >>XP_005252153 (OMIM: 608360,613506) PREDICTED: volume-r (810 aa) initn: 5363 init1: 5363 opt: 5363 Z-score: 5295.4 bits: 990.7 E(85289): 0 Smith-Waterman score: 5363; 100.0% identity (100.0% similar) in 810 aa overlap (1-810:1-810) 10 20 30 40 50 60 pF1KSD MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK 730 740 750 760 770 780 790 800 810 pF1KSD RSGLVVEEDLFNTLPPEVKERLWRADKEQA :::::::::::::::::::::::::::::: XP_005 RSGLVVEEDLFNTLPPEVKERLWRADKEQA 790 800 810 >>XP_011517167 (OMIM: 608360,613506) PREDICTED: volume-r (810 aa) initn: 5363 init1: 5363 opt: 5363 Z-score: 5295.4 bits: 990.7 E(85289): 0 Smith-Waterman score: 5363; 100.0% identity (100.0% similar) in 810 aa overlap (1-810:1-810) 10 20 30 40 50 60 pF1KSD MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHW 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDIE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREES 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIR 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KSD ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLK 730 740 750 760 770 780 790 800 810 pF1KSD RSGLVVEEDLFNTLPPEVKERLWRADKEQA :::::::::::::::::::::::::::::: XP_011 RSGLVVEEDLFNTLPPEVKERLWRADKEQA 790 800 810 >>XP_005270760 (OMIM: 612888) PREDICTED: volume-regulate (803 aa) initn: 3161 init1: 2464 opt: 3188 Z-score: 3150.0 bits: 593.7 E(85289): 1e-168 Smith-Waterman score: 3188; 59.0% identity (82.8% similar) in 803 aa overlap (1-802:1-796) 10 20 30 40 50 pF1KSD MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMIC-LPCKW :: .:::. .::.: .:.::::::::: ::...::..::..:.::.::....: :::: XP_005 MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KSD VTKDSCNDSFRGWAAPGPEPTYPNSTILPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLH . : . : . :.. : : : :. :: :.::.:.::::::..:: XP_005 EFDNHCAVPWDILKASMNTSSNPGT---PLPL--PLRIQNDLHRQQYSYIDAVCYEKQLH 70 80 90 100 110 120 130 140 150 160 170 pF1KSD WFAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVE ::::.:::::::::::: ::::::...: :::.:::::.:: ::::::::::::::::.: XP_005 WFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVAILHKCFDSPWTTRALSETVAE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KSD ESDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQ .: .:: ... .:: : :... : . .:.. .. ..::::::::: XP_005 QSVRPLKLSK--SKILLSSSGCSADIDSGKQSLPYPQPGLESAGIESPTSSVLDKKEGEQ 180 190 200 210 220 230 240 250 260 270 280 290 pF1KSD AKALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFILIICYTVYYVHNIKFDVDCTVDI :::.:::::.:: :::. ::.::.:..: :.::: :.::: :. :.. .: ...::.::. XP_005 AKAIFEKVKRFRMHVEQKDIIYRVYLKQIIVKVILFVLIITYVPYFLTHITLEIDCSVDV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KSD ESLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREE ...:::. :.:.. :: .::.:::::. :::.::: :.:::::: :::.::::..::. XP_005 QAFTGYKRYQCVYSLAEIFKVLASFYVILVILYGLTSSYSLWWMLRSSLKQYSFEALREK 300 310 320 330 340 350 360 370 380 390 400 410 pF1KSD SSYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQR :.:::::::::::::.::: :::::::::::..::::::::::.:.:::::::..::... XP_005 SNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVEKLKSK 360 370 380 390 400 410 420 430 440 450 460 470 pF1KSD LTKNAQDKLELHLFMLSGIPDTVFDLVELEVLKLELIPDVTIPPSIAQLTGLKELWLYHT :.::::::.:::::::.:.::.::.:.:.:::.:::::.: .: ...::..:::: .::. XP_005 LVKNAQDKIELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPSAVSQLVNLKELRVYHS 420 430 440 450 460 470 480 490 500 510 520 530 pF1KSD AAKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDG . .. ::::::.:::. :..:::.. .:: :.. ::.:.::.:.: . :. . ..: XP_005 SLVVDHPALAFLEENLKILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSTMQLEG 480 490 500 510 520 530 540 550 560 570 580 590 pF1KSD LRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELI ...:: :..: :::.::..::::::. :::::..:::.::.:::.::::.:: :::: XP_005 FQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELI 540 550 560 570 580 590 600 610 620 630 640 650 pF1KSD RCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIG :::::::::::::.::.:.::..:::::.:::::::::. :.:::::.:.::::: ::: XP_005 SCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIAYIPAQIG 600 610 620 630 640 650 660 670 680 690 700 710 pF1KSD NLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANR :.:::.: :..:.::..: ::: : ::.:::::.:.:::.: .: :.::: .:.: : XP_005 ALSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLSNLQYFAVTNNN 660 670 680 690 700 710 720 730 740 750 760 770 pF1KSD IETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLL :: :: ::::.::. : ::.: :..: .::::.:::..:: :: :: :: :: : : XP_005 IEMLPDGLFQCKKLQCLLLGKNSLMNLSPHVGELSNLTHLELIGNYLETLPPELEGCQSL 720 730 740 750 760 770 780 790 800 810 pF1KSD KRSGLVVEEDLFNTLPPEVKERLWRADKEQA ::. :.:::.:.:::: : ::: XP_005 KRNCLIVEENLLNTLPLPVTERLQTCLDKC 780 790 800 810 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 06:16:12 2016 done: Thu Nov 3 06:16:14 2016 Total Scan time: 12.370 Total Display time: 0.330 Function used was FASTA [36.3.4 Apr, 2011]